Amino acid dipepetide frequency for Grapevine enamovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.229AlaAla: 3.229 ± 0.814
1.292AlaCys: 1.292 ± 0.355
5.812AlaAsp: 5.812 ± 1.177
5.166AlaGlu: 5.166 ± 0.704
0.969AlaPhe: 0.969 ± 0.641
7.749AlaGly: 7.749 ± 2.933
0.969AlaHis: 0.969 ± 0.345
2.26AlaIle: 2.26 ± 0.487
2.583AlaLys: 2.583 ± 0.531
7.427AlaLeu: 7.427 ± 1.535
2.26AlaMet: 2.26 ± 0.919
1.937AlaAsn: 1.937 ± 0.674
4.843AlaPro: 4.843 ± 0.838
2.26AlaGln: 2.26 ± 0.525
5.812AlaArg: 5.812 ± 0.686
5.489AlaSer: 5.489 ± 1.406
3.229AlaThr: 3.229 ± 0.768
5.812AlaVal: 5.812 ± 1.559
0.0AlaTrp: 0.0 ± 0.0
3.229AlaTyr: 3.229 ± 0.539
0.0AlaXaa: 0.0 ± 0.0
Cys
1.292CysAla: 1.292 ± 0.521
0.0CysCys: 0.0 ± 0.0
0.969CysAsp: 0.969 ± 0.377
1.614CysGlu: 1.614 ± 0.621
0.969CysPhe: 0.969 ± 0.32
3.229CysGly: 3.229 ± 0.538
1.292CysHis: 1.292 ± 0.466
2.26CysIle: 2.26 ± 0.316
0.969CysLys: 0.969 ± 0.345
1.614CysLeu: 1.614 ± 0.494
0.0CysMet: 0.0 ± 0.0
0.323CysAsn: 0.323 ± 0.308
0.646CysPro: 0.646 ± 0.317
0.0CysGln: 0.0 ± 0.0
1.614CysArg: 1.614 ± 0.494
3.552CysSer: 3.552 ± 0.541
0.646CysThr: 0.646 ± 0.312
1.614CysVal: 1.614 ± 0.398
0.646CysTrp: 0.646 ± 0.233
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.583AspAla: 2.583 ± 0.385
0.969AspCys: 0.969 ± 0.447
4.198AspAsp: 4.198 ± 0.838
2.583AspGlu: 2.583 ± 0.891
3.229AspPhe: 3.229 ± 0.949
3.229AspGly: 3.229 ± 1.095
0.323AspHis: 0.323 ± 0.308
2.26AspIle: 2.26 ± 1.192
1.937AspLys: 1.937 ± 0.491
4.521AspLeu: 4.521 ± 1.325
0.969AspMet: 0.969 ± 0.345
0.646AspAsn: 0.646 ± 0.616
0.969AspPro: 0.969 ± 0.32
2.583AspGln: 2.583 ± 0.801
2.906AspArg: 2.906 ± 1.051
5.812AspSer: 5.812 ± 0.867
1.614AspThr: 1.614 ± 0.773
2.906AspVal: 2.906 ± 1.07
1.614AspTrp: 1.614 ± 0.805
4.198AspTyr: 4.198 ± 0.871
0.0AspXaa: 0.0 ± 0.0
Glu
3.875GluAla: 3.875 ± 0.506
0.646GluCys: 0.646 ± 0.432
4.198GluAsp: 4.198 ± 1.152
3.229GluGlu: 3.229 ± 0.823
0.323GluPhe: 0.323 ± 0.216
3.552GluGly: 3.552 ± 1.091
1.292GluHis: 1.292 ± 0.636
1.937GluIle: 1.937 ± 0.632
0.969GluLys: 0.969 ± 0.32
2.906GluLeu: 2.906 ± 1.034
1.292GluMet: 1.292 ± 0.225
1.614GluAsn: 1.614 ± 0.547
5.166GluPro: 5.166 ± 0.845
2.583GluGln: 2.583 ± 0.827
3.229GluArg: 3.229 ± 0.538
6.135GluSer: 6.135 ± 0.419
1.292GluThr: 1.292 ± 0.625
4.521GluVal: 4.521 ± 0.9
0.969GluTrp: 0.969 ± 0.433
1.292GluTyr: 1.292 ± 0.225
0.0GluXaa: 0.0 ± 0.0
Phe
2.26PheAla: 2.26 ± 0.931
0.323PheCys: 0.323 ± 0.216
3.552PheAsp: 3.552 ± 0.648
1.292PheGlu: 1.292 ± 0.466
1.614PhePhe: 1.614 ± 0.283
2.906PheGly: 2.906 ± 0.338
0.969PheHis: 0.969 ± 0.345
0.646PheIle: 0.646 ± 0.233
2.583PheLys: 2.583 ± 1.052
3.875PheLeu: 3.875 ± 0.698
0.969PheMet: 0.969 ± 0.673
0.969PheAsn: 0.969 ± 0.345
2.26PhePro: 2.26 ± 0.505
1.937PheGln: 1.937 ± 0.558
1.937PheArg: 1.937 ± 0.755
3.229PheSer: 3.229 ± 0.622
2.26PheThr: 2.26 ± 0.99
2.26PheVal: 2.26 ± 0.548
1.614PheTrp: 1.614 ± 0.349
0.323PheTyr: 0.323 ± 0.216
0.0PheXaa: 0.0 ± 0.0
Gly
8.072GlyAla: 8.072 ± 1.744
2.583GlyCys: 2.583 ± 0.397
3.229GlyAsp: 3.229 ± 1.434
2.906GlyGlu: 2.906 ± 1.034
5.812GlyPhe: 5.812 ± 1.299
5.166GlyGly: 5.166 ± 1.552
0.969GlyHis: 0.969 ± 0.826
2.26GlyIle: 2.26 ± 0.358
5.489GlyLys: 5.489 ± 0.624
7.104GlyLeu: 7.104 ± 0.854
1.292GlyMet: 1.292 ± 0.225
4.198GlyAsn: 4.198 ± 1.509
3.875GlyPro: 3.875 ± 0.801
2.583GlyGln: 2.583 ± 0.531
3.552GlyArg: 3.552 ± 0.697
7.104GlySer: 7.104 ± 1.063
3.552GlyThr: 3.552 ± 0.907
8.718GlyVal: 8.718 ± 0.658
0.646GlyTrp: 0.646 ± 0.317
1.937GlyTyr: 1.937 ± 0.34
0.0GlyXaa: 0.0 ± 0.0
His
0.323HisAla: 0.323 ± 0.216
1.292HisCys: 1.292 ± 0.466
0.646HisAsp: 0.646 ± 0.616
0.323HisGlu: 0.323 ± 0.216
0.646HisPhe: 0.646 ± 0.233
0.646HisGly: 0.646 ± 0.233
0.969HisHis: 0.969 ± 0.923
1.937HisIle: 1.937 ± 0.335
0.969HisLys: 0.969 ± 0.19
2.906HisLeu: 2.906 ± 0.624
0.323HisMet: 0.323 ± 0.308
0.646HisAsn: 0.646 ± 0.233
0.969HisPro: 0.969 ± 0.32
0.323HisGln: 0.323 ± 0.216
0.323HisArg: 0.323 ± 0.289
1.292HisSer: 1.292 ± 0.526
2.583HisThr: 2.583 ± 0.232
2.583HisVal: 2.583 ± 0.561
0.969HisTrp: 0.969 ± 0.19
1.614HisTyr: 1.614 ± 1.383
0.0HisXaa: 0.0 ± 0.0
Ile
5.489IleAla: 5.489 ± 1.226
2.26IleCys: 2.26 ± 0.889
2.26IleAsp: 2.26 ± 0.358
2.583IleGlu: 2.583 ± 0.819
0.969IlePhe: 0.969 ± 0.345
1.614IleGly: 1.614 ± 0.398
0.969IleHis: 0.969 ± 0.19
0.969IleIle: 0.969 ± 0.592
2.26IleLys: 2.26 ± 0.361
3.875IleLeu: 3.875 ± 1.147
0.969IleMet: 0.969 ± 0.19
1.937IleAsn: 1.937 ± 0.85
1.614IlePro: 1.614 ± 0.221
1.614IleGln: 1.614 ± 0.429
2.906IleArg: 2.906 ± 0.821
2.26IleSer: 2.26 ± 0.8
2.906IleThr: 2.906 ± 0.571
3.229IleVal: 3.229 ± 0.371
0.969IleTrp: 0.969 ± 0.478
0.646IleTyr: 0.646 ± 0.233
0.0IleXaa: 0.0 ± 0.0
Lys
4.198LysAla: 4.198 ± 1.421
0.646LysCys: 0.646 ± 0.432
3.229LysAsp: 3.229 ± 0.884
3.552LysGlu: 3.552 ± 1.104
0.969LysPhe: 0.969 ± 0.502
5.812LysGly: 5.812 ± 0.368
0.646LysHis: 0.646 ± 0.432
1.614LysIle: 1.614 ± 0.569
4.843LysLys: 4.843 ± 2.048
2.906LysLeu: 2.906 ± 0.703
1.614LysMet: 1.614 ± 0.349
0.969LysAsn: 0.969 ± 0.478
5.166LysPro: 5.166 ± 1.088
0.969LysGln: 0.969 ± 0.19
1.614LysArg: 1.614 ± 0.643
4.198LysSer: 4.198 ± 0.506
2.906LysThr: 2.906 ± 0.789
3.875LysVal: 3.875 ± 1.313
1.937LysTrp: 1.937 ± 0.934
0.646LysTyr: 0.646 ± 0.233
0.0LysXaa: 0.0 ± 0.0
Leu
4.843LeuAla: 4.843 ± 0.936
2.906LeuCys: 2.906 ± 0.433
5.489LeuAsp: 5.489 ± 1.132
3.875LeuGlu: 3.875 ± 1.136
3.229LeuPhe: 3.229 ± 0.734
4.521LeuGly: 4.521 ± 1.327
3.552LeuHis: 3.552 ± 1.013
4.521LeuIle: 4.521 ± 0.873
3.229LeuLys: 3.229 ± 0.619
8.072LeuLeu: 8.072 ± 1.164
3.552LeuMet: 3.552 ± 0.795
2.906LeuAsn: 2.906 ± 0.443
6.781LeuPro: 6.781 ± 0.977
3.552LeuGln: 3.552 ± 0.978
4.198LeuArg: 4.198 ± 1.035
4.521LeuSer: 4.521 ± 0.561
7.427LeuThr: 7.427 ± 0.531
3.875LeuVal: 3.875 ± 0.825
0.646LeuTrp: 0.646 ± 0.233
2.906LeuTyr: 2.906 ± 0.443
0.323LeuXaa: 0.323 ± 0.318
Met
1.937MetAla: 1.937 ± 0.27
0.0MetCys: 0.0 ± 0.0
0.969MetAsp: 0.969 ± 0.502
0.969MetGlu: 0.969 ± 0.592
0.969MetPhe: 0.969 ± 0.19
2.583MetGly: 2.583 ± 0.79
0.646MetHis: 0.646 ± 0.233
2.583MetIle: 2.583 ± 0.721
0.323MetLys: 0.323 ± 0.318
2.26MetLeu: 2.26 ± 0.755
0.646MetMet: 0.646 ± 0.233
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.646MetGln: 0.646 ± 0.233
2.26MetArg: 2.26 ± 0.316
2.906MetSer: 2.906 ± 0.81
2.583MetThr: 2.583 ± 0.531
2.906MetVal: 2.906 ± 1.04
1.614MetTrp: 1.614 ± 0.494
0.646MetTyr: 0.646 ± 0.233
0.0MetXaa: 0.0 ± 0.0
Asn
2.583AsnAla: 2.583 ± 1.211
0.969AsnCys: 0.969 ± 0.478
1.292AsnAsp: 1.292 ± 0.225
0.969AsnGlu: 0.969 ± 0.587
1.614AsnPhe: 1.614 ± 0.773
4.521AsnGly: 4.521 ± 0.326
0.0AsnHis: 0.0 ± 0.0
0.323AsnIle: 0.323 ± 0.308
0.969AsnLys: 0.969 ± 0.345
1.614AsnLeu: 1.614 ± 0.349
0.969AsnMet: 0.969 ± 0.345
0.323AsnAsn: 0.323 ± 0.308
2.26AsnPro: 2.26 ± 0.667
2.906AsnGln: 2.906 ± 0.703
2.26AsnArg: 2.26 ± 0.723
4.198AsnSer: 4.198 ± 1.152
1.614AsnThr: 1.614 ± 0.729
0.646AsnVal: 0.646 ± 0.317
1.614AsnTrp: 1.614 ± 0.468
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
5.166ProAla: 5.166 ± 0.748
0.969ProCys: 0.969 ± 0.19
2.906ProAsp: 2.906 ± 0.499
2.906ProGlu: 2.906 ± 0.973
0.969ProPhe: 0.969 ± 0.478
3.875ProGly: 3.875 ± 0.462
2.26ProHis: 2.26 ± 0.361
5.812ProIle: 5.812 ± 1.313
3.552ProLys: 3.552 ± 1.543
3.552ProLeu: 3.552 ± 0.459
2.583ProMet: 2.583 ± 0.317
2.26ProAsn: 2.26 ± 0.506
6.135ProPro: 6.135 ± 2.541
2.26ProGln: 2.26 ± 0.8
5.489ProArg: 5.489 ± 2.594
2.906ProSer: 2.906 ± 0.906
5.166ProThr: 5.166 ± 1.051
2.906ProVal: 2.906 ± 1.47
0.323ProTrp: 0.323 ± 0.318
1.614ProTyr: 1.614 ± 0.895
0.0ProXaa: 0.0 ± 0.0
Gln
1.937GlnAla: 1.937 ± 0.689
0.646GlnCys: 0.646 ± 0.636
0.969GlnAsp: 0.969 ± 0.433
4.198GlnGlu: 4.198 ± 1.775
0.646GlnPhe: 0.646 ± 0.569
4.521GlnGly: 4.521 ± 0.517
0.323GlnHis: 0.323 ± 0.318
1.292GlnIle: 1.292 ± 0.225
3.552GlnLys: 3.552 ± 0.929
0.969GlnLeu: 0.969 ± 0.433
0.646GlnMet: 0.646 ± 0.569
1.614GlnAsn: 1.614 ± 0.494
3.552GlnPro: 3.552 ± 1.277
0.969GlnGln: 0.969 ± 0.19
2.583GlnArg: 2.583 ± 0.833
5.489GlnSer: 5.489 ± 0.586
2.26GlnThr: 2.26 ± 0.513
4.198GlnVal: 4.198 ± 0.725
0.0GlnTrp: 0.0 ± 0.0
0.646GlnTyr: 0.646 ± 0.233
0.0GlnXaa: 0.0 ± 0.0
Arg
4.198ArgAla: 4.198 ± 0.864
0.646ArgCys: 0.646 ± 0.317
1.292ArgAsp: 1.292 ± 0.682
1.292ArgGlu: 1.292 ± 0.526
2.583ArgPhe: 2.583 ± 0.548
5.489ArgGly: 5.489 ± 1.555
1.292ArgHis: 1.292 ± 0.438
2.26ArgIle: 2.26 ± 0.549
2.583ArgLys: 2.583 ± 0.619
5.812ArgLeu: 5.812 ± 1.106
2.583ArgMet: 2.583 ± 1.052
1.937ArgAsn: 1.937 ± 0.51
3.229ArgPro: 3.229 ± 1.615
2.583ArgGln: 2.583 ± 0.989
6.135ArgArg: 6.135 ± 1.589
5.166ArgSer: 5.166 ± 0.856
3.552ArgThr: 3.552 ± 0.918
4.521ArgVal: 4.521 ± 0.89
0.969ArgTrp: 0.969 ± 0.592
1.292ArgTyr: 1.292 ± 0.419
0.0ArgXaa: 0.0 ± 0.0
Ser
7.104SerAla: 7.104 ± 0.813
4.198SerCys: 4.198 ± 0.655
2.583SerAsp: 2.583 ± 0.827
3.875SerGlu: 3.875 ± 1.189
3.552SerPhe: 3.552 ± 0.978
6.458SerGly: 6.458 ± 0.775
2.26SerHis: 2.26 ± 0.641
4.521SerIle: 4.521 ± 1.294
5.812SerLys: 5.812 ± 1.115
6.135SerLeu: 6.135 ± 1.203
1.614SerMet: 1.614 ± 0.384
2.906SerAsn: 2.906 ± 0.571
6.135SerPro: 6.135 ± 1.718
4.521SerGln: 4.521 ± 0.938
5.166SerArg: 5.166 ± 1.423
6.458SerSer: 6.458 ± 1.598
3.552SerThr: 3.552 ± 0.883
3.552SerVal: 3.552 ± 0.673
3.229SerTrp: 3.229 ± 0.424
1.292SerTyr: 1.292 ± 0.225
0.0SerXaa: 0.0 ± 0.0
Thr
1.937ThrAla: 1.937 ± 0.698
0.646ThrCys: 0.646 ± 0.636
2.906ThrAsp: 2.906 ± 1.048
2.583ThrGlu: 2.583 ± 1.175
1.937ThrPhe: 1.937 ± 0.661
4.521ThrGly: 4.521 ± 0.712
0.646ThrHis: 0.646 ± 0.432
1.614ThrIle: 1.614 ± 1.383
1.614ThrLys: 1.614 ± 0.644
5.489ThrLeu: 5.489 ± 0.42
3.229ThrMet: 3.229 ± 0.272
1.292ThrAsn: 1.292 ± 0.524
4.521ThrPro: 4.521 ± 1.253
4.521ThrGln: 4.521 ± 0.763
2.583ThrArg: 2.583 ± 0.827
6.458ThrSer: 6.458 ± 0.508
6.458ThrThr: 6.458 ± 1.137
1.937ThrVal: 1.937 ± 0.381
1.292ThrTrp: 1.292 ± 0.376
2.583ThrTyr: 2.583 ± 0.412
0.0ThrXaa: 0.0 ± 0.0
Val
7.427ValAla: 7.427 ± 0.722
0.969ValCys: 0.969 ± 0.345
2.583ValAsp: 2.583 ± 0.412
2.583ValGlu: 2.583 ± 0.5
2.906ValPhe: 2.906 ± 0.42
5.812ValGly: 5.812 ± 0.699
2.26ValHis: 2.26 ± 0.361
0.969ValIle: 0.969 ± 0.32
3.875ValLys: 3.875 ± 1.613
6.781ValLeu: 6.781 ± 0.917
1.614ValMet: 1.614 ± 0.283
2.906ValAsn: 2.906 ± 1.04
3.229ValPro: 3.229 ± 0.977
2.583ValGln: 2.583 ± 0.711
3.229ValArg: 3.229 ± 0.538
6.135ValSer: 6.135 ± 1.144
3.552ValThr: 3.552 ± 0.714
5.166ValVal: 5.166 ± 2.037
2.906ValTrp: 2.906 ± 1.034
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
2.26TrpAla: 2.26 ± 0.767
0.969TrpCys: 0.969 ± 0.447
0.323TrpAsp: 0.323 ± 0.216
1.614TrpGlu: 1.614 ± 0.283
2.583TrpPhe: 2.583 ± 0.397
1.614TrpGly: 1.614 ± 0.569
0.0TrpHis: 0.0 ± 0.0
0.646TrpIle: 0.646 ± 0.312
1.292TrpLys: 1.292 ± 0.887
3.875TrpLeu: 3.875 ± 1.379
0.0TrpMet: 0.0 ± 0.0
0.323TrpAsn: 0.323 ± 0.216
1.937TrpPro: 1.937 ± 0.402
1.292TrpGln: 1.292 ± 0.225
0.646TrpArg: 0.646 ± 0.233
0.646TrpSer: 0.646 ± 0.432
0.646TrpThr: 0.646 ± 0.312
0.323TrpVal: 0.323 ± 0.216
0.0TrpTrp: 0.0 ± 0.0
0.969TrpTyr: 0.969 ± 0.32
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.614TyrAla: 1.614 ± 0.494
0.323TyrCys: 0.323 ± 0.318
0.646TyrAsp: 0.646 ± 0.616
2.906TyrGlu: 2.906 ± 0.432
1.292TyrPhe: 1.292 ± 0.355
3.229TyrGly: 3.229 ± 0.614
0.646TyrHis: 0.646 ± 0.569
1.614TyrIle: 1.614 ± 0.468
2.906TyrLys: 2.906 ± 0.691
3.229TyrLeu: 3.229 ± 0.627
0.0TyrMet: 0.0 ± 0.0
1.937TyrAsn: 1.937 ± 0.491
0.323TyrPro: 0.323 ± 0.308
0.323TyrGln: 0.323 ± 0.216
0.969TyrArg: 0.969 ± 0.641
1.292TyrSer: 1.292 ± 0.225
0.969TyrThr: 0.969 ± 0.19
1.937TyrVal: 1.937 ± 0.669
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.323XaaTyr: 0.323 ± 0.318
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3098 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski