Amino acid dipepetide frequency for Eucalyptus grandis (Flooded gum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.116AlaAla: 7.116 ± 0.038	1.361AlaCys: 1.361 ± 0.011	3.262AlaAsp: 3.262 ± 0.016	4.241AlaGlu: 4.241 ± 0.021	2.891AlaPhe: 2.891 ± 0.014	4.603AlaGly: 4.603 ± 0.019	1.393AlaHis: 1.393 ± 0.009	3.817AlaIle: 3.817 ± 0.019	3.87AlaLys: 3.87 ± 0.017	7.108AlaLeu: 7.108 ± 0.026	1.874AlaMet: 1.874 ± 0.012	2.615AlaAsn: 2.615 ± 0.012	3.088AlaPro: 3.088 ± 0.017	2.122AlaGln: 2.122 ± 0.014	3.893AlaArg: 3.893 ± 0.019	6.314AlaSer: 6.314 ± 0.021	3.598AlaThr: 3.598 ± 0.016	5.016AlaVal: 5.016 ± 0.02	0.851AlaTrp: 0.851 ± 0.008	1.873AlaTyr: 1.873 ± 0.012	0.0AlaXaa: 0.0 ± 0.0
Cys	1.077CysAla: 1.077 ± 0.011	0.561CysCys: 0.561 ± 0.007	0.907CysAsp: 0.907 ± 0.009	0.951CysGlu: 0.951 ± 0.008	0.953CysPhe: 0.953 ± 0.009	1.527CysGly: 1.527 ± 0.011	0.52CysHis: 0.52 ± 0.006	1.004CysIle: 1.004 ± 0.008	1.095CysLys: 1.095 ± 0.009	2.055CysLeu: 2.055 ± 0.014	0.459CysMet: 0.459 ± 0.005	0.819CysAsn: 0.819 ± 0.008	1.008CysPro: 1.008 ± 0.01	0.641CysGln: 0.641 ± 0.007	1.166CysArg: 1.166 ± 0.009	1.852CysSer: 1.852 ± 0.013	0.889CysThr: 0.889 ± 0.007	1.063CysVal: 1.063 ± 0.008	0.27CysTrp: 0.27 ± 0.004	0.538CysTyr: 0.538 ± 0.005	0.0CysXaa: 0.0 ± 0.0
Asp	3.582AspAla: 3.582 ± 0.015	1.007AspCys: 1.007 ± 0.008	3.383AspAsp: 3.383 ± 0.019	3.712AspGlu: 3.712 ± 0.017	2.373AspPhe: 2.373 ± 0.013	4.07AspGly: 4.07 ± 0.018	1.227AspHis: 1.227 ± 0.009	2.937AspIle: 2.937 ± 0.016	2.49AspLys: 2.49 ± 0.013	5.467AspLeu: 5.467 ± 0.023	1.301AspMet: 1.301 ± 0.009	1.901AspAsn: 1.901 ± 0.011	2.757AspPro: 2.757 ± 0.013	1.701AspGln: 1.701 ± 0.011	2.567AspArg: 2.567 ± 0.014	3.933AspSer: 3.933 ± 0.018	2.013AspThr: 2.013 ± 0.012	3.746AspVal: 3.746 ± 0.016	0.739AspTrp: 0.739 ± 0.007	1.497AspTyr: 1.497 ± 0.01	0.0AspXaa: 0.0 ± 0.0
Glu	4.766GluAla: 4.766 ± 0.022	0.967GluCys: 0.967 ± 0.008	3.828GluAsp: 3.828 ± 0.016	5.888GluGlu: 5.888 ± 0.03	2.368GluPhe: 2.368 ± 0.014	3.944GluGly: 3.944 ± 0.014	1.241GluHis: 1.241 ± 0.01	3.743GluIle: 3.743 ± 0.017	4.313GluLys: 4.313 ± 0.024	6.17GluLeu: 6.17 ± 0.028	1.762GluMet: 1.762 ± 0.01	2.71GluAsn: 2.71 ± 0.014	2.068GluPro: 2.068 ± 0.01	1.999GluGln: 1.999 ± 0.012	3.592GluArg: 3.592 ± 0.019	4.426GluSer: 4.426 ± 0.021	2.751GluThr: 2.751 ± 0.013	4.279GluVal: 4.279 ± 0.016	0.788GluTrp: 0.788 ± 0.006	1.609GluTyr: 1.609 ± 0.01	0.0GluXaa: 0.0 ± 0.0
Phe	2.66PheAla: 2.66 ± 0.014	0.906PheCys: 0.906 ± 0.008	2.319PheAsp: 2.319 ± 0.012	2.224PheGlu: 2.224 ± 0.013	1.995PhePhe: 1.995 ± 0.013	3.245PheGly: 3.245 ± 0.014	1.07PheHis: 1.07 ± 0.009	1.978PheIle: 1.978 ± 0.011	1.989PheLys: 1.989 ± 0.011	4.559PheLeu: 4.559 ± 0.02	0.989PheMet: 0.989 ± 0.008	1.662PheAsn: 1.662 ± 0.011	2.103PhePro: 2.103 ± 0.014	1.446PheGln: 1.446 ± 0.011	2.132PheArg: 2.132 ± 0.011	3.988PheSer: 3.988 ± 0.017	1.989PheThr: 1.989 ± 0.012	2.72PheVal: 2.72 ± 0.013	0.592PheTrp: 0.592 ± 0.006	1.28PheTyr: 1.28 ± 0.009	0.0PheXaa: 0.0 ± 0.0
Gly	4.207GlyAla: 4.207 ± 0.02	1.449GlyCys: 1.449 ± 0.012	3.606GlyAsp: 3.606 ± 0.015	3.869GlyGlu: 3.869 ± 0.017	3.182GlyPhe: 3.182 ± 0.015	5.895GlyGly: 5.895 ± 0.032	1.67GlyHis: 1.67 ± 0.011	3.695GlyIle: 3.695 ± 0.018	4.057GlyLys: 4.057 ± 0.019	6.351GlyLeu: 6.351 ± 0.019	1.607GlyMet: 1.607 ± 0.01	3.239GlyAsn: 3.239 ± 0.019	2.726GlyPro: 2.726 ± 0.015	2.264GlyGln: 2.264 ± 0.014	3.972GlyArg: 3.972 ± 0.019	6.186GlySer: 6.186 ± 0.022	3.389GlyThr: 3.389 ± 0.016	4.351GlyVal: 4.351 ± 0.018	0.978GlyTrp: 0.978 ± 0.008	2.116GlyTyr: 2.116 ± 0.013	0.0GlyXaa: 0.0 ± 0.0
His	1.485HisAla: 1.485 ± 0.009	0.546HisCys: 0.546 ± 0.006	1.141HisAsp: 1.141 ± 0.009	1.335HisGlu: 1.335 ± 0.009	1.066HisPhe: 1.066 ± 0.008	1.841HisGly: 1.841 ± 0.013	0.933HisHis: 0.933 ± 0.011	1.185HisIle: 1.185 ± 0.009	1.107HisLys: 1.107 ± 0.009	2.673HisLeu: 2.673 ± 0.014	0.562HisMet: 0.562 ± 0.006	0.919HisAsn: 0.919 ± 0.008	1.382HisPro: 1.382 ± 0.009	0.94HisGln: 0.94 ± 0.007	1.532HisArg: 1.532 ± 0.01	1.81HisSer: 1.81 ± 0.011	0.863HisThr: 0.863 ± 0.008	1.575HisVal: 1.575 ± 0.009	0.32HisTrp: 0.32 ± 0.004	0.668HisTyr: 0.668 ± 0.006	0.0HisXaa: 0.0 ± 0.0
Ile	3.71IleAla: 3.71 ± 0.014	1.108IleCys: 1.108 ± 0.009	2.79IleAsp: 2.79 ± 0.014	3.095IleGlu: 3.095 ± 0.016	2.286IlePhe: 2.286 ± 0.014	3.684IleGly: 3.684 ± 0.02	1.264IleHis: 1.264 ± 0.008	2.722IleIle: 2.722 ± 0.016	2.759IleLys: 2.759 ± 0.013	5.282IleLeu: 5.282 ± 0.02	1.164IleMet: 1.164 ± 0.009	1.99IleAsn: 1.99 ± 0.013	3.157IlePro: 3.157 ± 0.022	1.838IleGln: 1.838 ± 0.011	2.612IleArg: 2.612 ± 0.012	4.711IleSer: 4.711 ± 0.018	2.471IleThr: 2.471 ± 0.012	3.457IleVal: 3.457 ± 0.016	0.692IleTrp: 0.692 ± 0.006	1.497IleTyr: 1.497 ± 0.01	0.0IleXaa: 0.0 ± 0.0
Lys	3.944LysAla: 3.944 ± 0.019	0.944LysCys: 0.944 ± 0.009	2.97LysAsp: 2.97 ± 0.013	4.164LysGlu: 4.164 ± 0.021	2.101LysPhe: 2.101 ± 0.01	3.516LysGly: 3.516 ± 0.015	1.257LysHis: 1.257 ± 0.01	3.09LysIle: 3.09 ± 0.014	4.112LysLys: 4.112 ± 0.024	6.082LysLeu: 6.082 ± 0.026	1.471LysMet: 1.471 ± 0.01	2.37LysAsn: 2.37 ± 0.014	2.447LysPro: 2.447 ± 0.016	2.042LysGln: 2.042 ± 0.012	3.445LysArg: 3.445 ± 0.018	4.297LysSer: 4.297 ± 0.022	2.463LysThr: 2.463 ± 0.013	3.735LysVal: 3.735 ± 0.015	0.789LysTrp: 0.789 ± 0.007	1.539LysTyr: 1.539 ± 0.011	0.0LysXaa: 0.0 ± 0.0
Leu	7.159LeuAla: 7.159 ± 0.023	1.953LeuCys: 1.953 ± 0.013	5.551LeuAsp: 5.551 ± 0.021	6.588LeuGlu: 6.588 ± 0.031	3.871LeuPhe: 3.871 ± 0.018	6.261LeuGly: 6.261 ± 0.019	2.811LeuHis: 2.811 ± 0.013	4.762LeuIle: 4.762 ± 0.019	6.11LeuLys: 6.11 ± 0.026	10.578LeuLeu: 10.578 ± 0.034	2.28LeuMet: 2.28 ± 0.011	3.948LeuAsn: 3.948 ± 0.02	5.633LeuPro: 5.633 ± 0.022	4.254LeuGln: 4.254 ± 0.019	6.045LeuArg: 6.045 ± 0.025	9.399LeuSer: 9.399 ± 0.04	4.648LeuThr: 4.648 ± 0.02	6.669LeuVal: 6.669 ± 0.022	1.276LeuTrp: 1.276 ± 0.009	2.625LeuTyr: 2.625 ± 0.014	0.0LeuXaa: 0.0 ± 0.0
Met	2.236MetAla: 2.236 ± 0.011	0.325MetCys: 0.325 ± 0.004	1.427MetAsp: 1.427 ± 0.01	1.924MetGlu: 1.924 ± 0.009	0.791MetPhe: 0.791 ± 0.007	1.663MetGly: 1.663 ± 0.011	0.557MetHis: 0.557 ± 0.006	1.218MetIle: 1.218 ± 0.01	1.586MetLys: 1.586 ± 0.01	2.265MetLeu: 2.265 ± 0.014	0.678MetMet: 0.678 ± 0.007	0.982MetAsn: 0.982 ± 0.008	1.117MetPro: 1.117 ± 0.009	0.897MetGln: 0.897 ± 0.009	1.337MetArg: 1.337 ± 0.009	1.825MetSer: 1.825 ± 0.01	1.124MetThr: 1.124 ± 0.009	1.665MetVal: 1.665 ± 0.011	0.293MetTrp: 0.293 ± 0.004	0.577MetTyr: 0.577 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.622AsnAla: 2.622 ± 0.013	0.904AsnCys: 0.904 ± 0.007	1.87AsnAsp: 1.87 ± 0.01	2.272AsnGlu: 2.272 ± 0.013	1.939AsnPhe: 1.939 ± 0.014	3.067AsnGly: 3.067 ± 0.016	0.996AsnHis: 0.996 ± 0.008	2.31AsnIle: 2.31 ± 0.014	2.082AsnLys: 2.082 ± 0.012	5.138AsnLeu: 5.138 ± 0.036	1.05AsnMet: 1.05 ± 0.009	2.03AsnAsn: 2.03 ± 0.016	2.135AsnPro: 2.135 ± 0.012	1.534AsnGln: 1.534 ± 0.011	1.975AsnArg: 1.975 ± 0.012	3.467AsnSer: 3.467 ± 0.018	1.675AsnThr: 1.675 ± 0.011	2.608AsnVal: 2.608 ± 0.012	0.546AsnTrp: 0.546 ± 0.005	1.231AsnTyr: 1.231 ± 0.009	0.0AsnXaa: 0.0 ± 0.0
Pro	3.381ProAla: 3.381 ± 0.017	0.804ProCys: 0.804 ± 0.008	2.597ProAsp: 2.597 ± 0.015	3.278ProGlu: 3.278 ± 0.015	1.963ProPhe: 1.963 ± 0.013	2.938ProGly: 2.938 ± 0.014	1.167ProHis: 1.167 ± 0.009	2.271ProIle: 2.271 ± 0.014	2.61ProLys: 2.61 ± 0.014	4.484ProLeu: 4.484 ± 0.018	1.006ProMet: 1.006 ± 0.008	2.157ProAsn: 2.157 ± 0.013	4.114ProPro: 4.114 ± 0.03	1.777ProGln: 1.777 ± 0.013	2.727ProArg: 2.727 ± 0.014	5.319ProSer: 5.319 ± 0.022	2.45ProThr: 2.45 ± 0.014	3.016ProVal: 3.016 ± 0.015	0.645ProTrp: 0.645 ± 0.007	1.271ProTyr: 1.271 ± 0.009	0.0ProXaa: 0.0 ± 0.0
Gln	2.344GlnAla: 2.344 ± 0.012	0.608GlnCys: 0.608 ± 0.006	1.607GlnAsp: 1.607 ± 0.011	2.295GlnGlu: 2.295 ± 0.012	1.34GlnPhe: 1.34 ± 0.01	2.169GlnGly: 2.169 ± 0.013	0.865GlnHis: 0.865 ± 0.007	1.941GlnIle: 1.941 ± 0.011	2.076GlnLys: 2.076 ± 0.013	3.692GlnLeu: 3.692 ± 0.019	0.95GlnMet: 0.95 ± 0.008	1.564GlnAsn: 1.564 ± 0.011	1.615GlnPro: 1.615 ± 0.014	1.739GlnGln: 1.739 ± 0.024	2.071GlnArg: 2.071 ± 0.012	2.689GlnSer: 2.689 ± 0.013	1.525GlnThr: 1.525 ± 0.011	2.311GlnVal: 2.311 ± 0.012	0.474GlnTrp: 0.474 ± 0.005	0.887GlnTyr: 0.887 ± 0.007	0.0GlnXaa: 0.0 ± 0.0
Arg	3.682ArgAla: 3.682 ± 0.021	1.064ArgCys: 1.064 ± 0.009	2.948ArgAsp: 2.948 ± 0.016	3.679ArgGlu: 3.679 ± 0.018	2.207ArgPhe: 2.207 ± 0.011	3.646ArgGly: 3.646 ± 0.019	1.376ArgHis: 1.376 ± 0.01	2.938ArgIle: 2.938 ± 0.014	3.599ArgLys: 3.599 ± 0.017	5.586ArgLeu: 5.586 ± 0.019	1.421ArgMet: 1.421 ± 0.009	2.425ArgAsn: 2.425 ± 0.013	2.602ArgPro: 2.602 ± 0.014	1.837ArgGln: 1.837 ± 0.011	4.445ArgArg: 4.445 ± 0.022	4.632ArgSer: 4.632 ± 0.023	2.497ArgThr: 2.497 ± 0.011	3.457ArgVal: 3.457 ± 0.013	0.823ArgTrp: 0.823 ± 0.007	1.479ArgTyr: 1.479 ± 0.009	0.0ArgXaa: 0.0 ± 0.0
Ser	5.631SerAla: 5.631 ± 0.022	1.849SerCys: 1.849 ± 0.01	4.137SerAsp: 4.137 ± 0.019	4.511SerGlu: 4.511 ± 0.016	4.03SerPhe: 4.03 ± 0.017	6.095SerGly: 6.095 ± 0.024	1.987SerHis: 1.987 ± 0.013	4.566SerIle: 4.566 ± 0.02	4.467SerLys: 4.467 ± 0.017	9.317SerLeu: 9.317 ± 0.032	2.113SerMet: 2.113 ± 0.011	3.775SerAsn: 3.775 ± 0.018	4.6SerPro: 4.6 ± 0.025	2.798SerGln: 2.798 ± 0.013	4.778SerArg: 4.778 ± 0.023	10.52SerSer: 10.52 ± 0.041	4.361SerThr: 4.361 ± 0.02	5.005SerVal: 5.005 ± 0.018	1.269SerTrp: 1.269 ± 0.009	2.287SerTyr: 2.287 ± 0.012	0.0SerXaa: 0.0 ± 0.0
Thr	3.41ThrAla: 3.41 ± 0.017	0.958ThrCys: 0.958 ± 0.009	2.154ThrAsp: 2.154 ± 0.013	2.586ThrGlu: 2.586 ± 0.013	2.013ThrPhe: 2.013 ± 0.011	3.316ThrGly: 3.316 ± 0.017	0.958ThrHis: 0.958 ± 0.008	2.628ThrIle: 2.628 ± 0.013	2.365ThrLys: 2.365 ± 0.013	4.63ThrLeu: 4.63 ± 0.019	1.149ThrMet: 1.149 ± 0.009	1.932ThrAsn: 1.932 ± 0.011	2.344ThrPro: 2.344 ± 0.015	1.382ThrGln: 1.382 ± 0.009	2.4ThrArg: 2.4 ± 0.012	4.314ThrSer: 4.314 ± 0.017	2.596ThrThr: 2.596 ± 0.013	3.216ThrVal: 3.216 ± 0.015	0.646ThrTrp: 0.646 ± 0.006	1.404ThrTyr: 1.404 ± 0.009	0.0ThrXaa: 0.0 ± 0.0
Val	5.191ValAla: 5.191 ± 0.022	1.13ValCys: 1.13 ± 0.009	3.673ValAsp: 3.673 ± 0.017	4.265ValGlu: 4.265 ± 0.019	2.648ValPhe: 2.648 ± 0.014	4.394ValGly: 4.394 ± 0.017	1.567ValHis: 1.567 ± 0.009	3.336ValIle: 3.336 ± 0.015	3.704ValLys: 3.704 ± 0.016	6.75ValLeu: 6.75 ± 0.021	1.521ValMet: 1.521 ± 0.009	2.498ValAsn: 2.498 ± 0.012	3.292ValPro: 3.292 ± 0.015	2.207ValGln: 2.207 ± 0.01	3.293ValArg: 3.293 ± 0.015	5.144ValSer: 5.144 ± 0.019	3.138ValThr: 3.138 ± 0.014	4.903ValVal: 4.903 ± 0.023	0.805ValTrp: 0.805 ± 0.007	1.997ValTyr: 1.997 ± 0.013	0.0ValXaa: 0.0 ± 0.0
Trp	0.859TrpAla: 0.859 ± 0.008	0.276TrpCys: 0.276 ± 0.004	0.719TrpAsp: 0.719 ± 0.008	0.777TrpGlu: 0.777 ± 0.007	0.568TrpPhe: 0.568 ± 0.006	0.79TrpGly: 0.79 ± 0.007	0.319TrpHis: 0.319 ± 0.004	0.727TrpIle: 0.727 ± 0.006	0.939TrpLys: 0.939 ± 0.009	1.342TrpLeu: 1.342 ± 0.009	0.355TrpMet: 0.355 ± 0.004	0.683TrpAsn: 0.683 ± 0.007	0.525TrpPro: 0.525 ± 0.006	0.466TrpGln: 0.466 ± 0.006	0.902TrpArg: 0.902 ± 0.008	1.064TrpSer: 1.064 ± 0.008	0.684TrpThr: 0.684 ± 0.007	0.866TrpVal: 0.866 ± 0.008	0.254TrpTrp: 0.254 ± 0.004	0.349TrpTyr: 0.349 ± 0.005	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.846TyrAla: 1.846 ± 0.011	0.635TyrCys: 0.635 ± 0.006	1.513TyrAsp: 1.513 ± 0.01	1.558TyrGlu: 1.558 ± 0.01	1.263TyrPhe: 1.263 ± 0.009	2.147TyrGly: 2.147 ± 0.015	0.702TyrHis: 0.702 ± 0.007	1.42TyrIle: 1.42 ± 0.009	1.447TyrLys: 1.447 ± 0.01	2.893TyrLeu: 2.893 ± 0.014	0.777TyrMet: 0.777 ± 0.007	1.234TyrAsn: 1.234 ± 0.009	1.259TyrPro: 1.259 ± 0.011	0.875TyrGln: 0.875 ± 0.007	1.464TyrArg: 1.464 ± 0.01	2.206TyrSer: 2.206 ± 0.012	1.278TyrThr: 1.278 ± 0.01	1.797TyrVal: 1.797 ± 0.012	0.409TyrTrp: 0.409 ± 0.005	0.953TyrTyr: 0.953 ± 0.008	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 44150 proteins (16844312 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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