Felis catus (Cat) (Felis silvestris catus)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Euther

Average proteome isoelectric point is 6.79

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 40225 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|M3WPP3|M3WPP3_FELCA Spermatogenesis associated 5 like 1 OS=Felis catus OX=9685 GN=SPATA5L1 PE=4 SV=4
MM1 pKa = 7.22EE2 pKa = 5.09AVVLIPYY9 pKa = 9.99VLGLLLLPLLAVVLCVRR26 pKa = 11.84CRR28 pKa = 11.84EE29 pKa = 4.27LPGSYY34 pKa = 10.75DD35 pKa = 3.3NTASDD40 pKa = 3.94SLAPSSIVIKK50 pKa = 10.5RR51 pKa = 11.84PPTLATWTPATSYY64 pKa = 10.76PPVTSYY70 pKa = 11.28PPLSQPDD77 pKa = 4.23LLPIPRR83 pKa = 11.84SPQPPGGSHH92 pKa = 6.82RR93 pKa = 11.84MPSSRR98 pKa = 11.84QDD100 pKa = 2.92SDD102 pKa = 3.47GANSVASYY110 pKa = 10.71EE111 pKa = 4.2NEE113 pKa = 3.86EE114 pKa = 4.31PACEE118 pKa = 5.26DD119 pKa = 3.55DD120 pKa = 6.59DD121 pKa = 4.6EE122 pKa = 6.88DD123 pKa = 5.49EE124 pKa = 4.94EE125 pKa = 4.44EE126 pKa = 4.91DD127 pKa = 4.15YY128 pKa = 11.46PNEE131 pKa = 4.39GYY133 pKa = 11.04LEE135 pKa = 4.18VLPDD139 pKa = 3.57STPATGTAVPPAPAPSNPGLRR160 pKa = 11.84DD161 pKa = 3.14SAFSMEE167 pKa = 4.23SGEE170 pKa = 4.99DD171 pKa = 3.63YY172 pKa = 11.66VNVPEE177 pKa = 4.61SEE179 pKa = 4.19EE180 pKa = 4.19SADD183 pKa = 3.6VSLDD187 pKa = 3.29GSRR190 pKa = 11.84EE191 pKa = 3.96YY192 pKa = 11.72VNVSQEE198 pKa = 4.24LPPVARR204 pKa = 11.84TEE206 pKa = 3.93PAILSSQNDD215 pKa = 3.92DD216 pKa = 4.02EE217 pKa = 5.46EE218 pKa = 5.21EE219 pKa = 4.2GAPDD223 pKa = 3.75YY224 pKa = 11.56EE225 pKa = 4.31NLQGLNN231 pKa = 3.55

Molecular weight: 24.73 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>sp|Q6SA95|FA9_FELCA Coagulation factor IX OS=Felis catus OX=9685 GN=F9 PE=3 SV=1
MM1 pKa = 7.1RR2 pKa = 11.84AKK4 pKa = 9.12WRR6 pKa = 11.84KK7 pKa = 9.1KK8 pKa = 9.32RR9 pKa = 11.84MRR11 pKa = 11.84RR12 pKa = 11.84LKK14 pKa = 10.08RR15 pKa = 11.84KK16 pKa = 8.21RR17 pKa = 11.84RR18 pKa = 11.84KK19 pKa = 8.46MRR21 pKa = 11.84QRR23 pKa = 11.84SKK25 pKa = 11.41

Molecular weight: 3.46 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

19655

20570

40225

24765678

13

27108

615.7

68.5

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.097 ± 0.014

2.194 ± 0.01

4.803 ± 0.008

7.082 ± 0.015

3.589 ± 0.008

6.672 ± 0.016

2.565 ± 0.007

4.301 ± 0.012

5.662 ± 0.015

9.83 ± 0.018

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.093 ± 0.005

3.572 ± 0.01

6.514 ± 0.02

4.726 ± 0.01

5.851 ± 0.012

8.355 ± 0.016

5.269 ± 0.009

6.013 ± 0.012

1.2 ± 0.004

2.61 ± 0.007
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski