Mustela putorius furo (European domestic ferret) (Mustela furo)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria;

Average proteome isoelectric point is 6.9

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 20057 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|M3XW37|M3XW37_MUSPF TLE family member 6 subcortical maternal complex member OS=Mustela putorius furo OX=9669 GN=TLE6 PE=3 SV=1
XX1 pKa = 6.1XXXXXXXARR10 pKa = 11.84QCLQRR15 pKa = 11.84ACEE18 pKa = 3.99AEE20 pKa = 4.29GAQFTSVPFGEE31 pKa = 4.59LDD33 pKa = 3.5FGEE36 pKa = 4.54TAVLDD41 pKa = 3.97AFYY44 pKa = 10.65DD45 pKa = 3.6ADD47 pKa = 3.83VAVVDD52 pKa = 4.06MSDD55 pKa = 3.43VSRR58 pKa = 11.84QPSLFYY64 pKa = 10.65HH65 pKa = 6.07LGVRR69 pKa = 11.84EE70 pKa = 4.26SFDD73 pKa = 3.15MANNVILYY81 pKa = 9.92HH82 pKa = 6.36DD83 pKa = 4.2TDD85 pKa = 3.21VDD87 pKa = 3.93TALSLL92 pKa = 3.91

Molecular weight: 9.27 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|M3YEZ9|M3YEZ9_MUSPF Solute carrier family 25 member 48 OS=Mustela putorius furo OX=9669 GN=SLC25A48 PE=3 SV=1
MM1 pKa = 7.63AGAIAKK7 pKa = 8.49PLNNRR12 pKa = 11.84RR13 pKa = 11.84RR14 pKa = 11.84RR15 pKa = 11.84GGEE18 pKa = 3.64GGGGGGRR25 pKa = 11.84RR26 pKa = 11.84RR27 pKa = 11.84RR28 pKa = 11.84RR29 pKa = 11.84RR30 pKa = 11.84RR31 pKa = 11.84KK32 pKa = 8.18RR33 pKa = 11.84RR34 pKa = 11.84KK35 pKa = 7.68GRR37 pKa = 11.84RR38 pKa = 11.84RR39 pKa = 11.84GRR41 pKa = 11.84RR42 pKa = 11.84RR43 pKa = 11.84KK44 pKa = 8.78IQKK47 pKa = 9.63

Molecular weight: 5.52 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

19903

154

20057

10723400

28

34392

534.6

59.47

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.084 ± 0.021

2.26 ± 0.017

4.712 ± 0.012

6.95 ± 0.027

3.694 ± 0.014

6.712 ± 0.027

2.589 ± 0.009

4.301 ± 0.019

5.602 ± 0.024

10.018 ± 0.026

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.105 ± 0.008

3.498 ± 0.012

6.447 ± 0.026

4.67 ± 0.018

5.828 ± 0.016

8.277 ± 0.022

5.263 ± 0.013

6.058 ± 0.018

1.235 ± 0.007

2.635 ± 0.01
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski