Amino acid dipepetide frequency for Little cherry virus 2

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.952AlaAla: 2.952 ± 0.711
1.054AlaCys: 1.054 ± 0.429
3.163AlaAsp: 3.163 ± 0.343
3.163AlaGlu: 3.163 ± 1.078
2.741AlaPhe: 2.741 ± 0.713
3.795AlaGly: 3.795 ± 0.952
0.633AlaHis: 0.633 ± 0.276
3.373AlaIle: 3.373 ± 0.621
3.163AlaLys: 3.163 ± 0.672
6.114AlaLeu: 6.114 ± 1.328
0.633AlaMet: 0.633 ± 0.317
2.53AlaAsn: 2.53 ± 1.121
1.054AlaPro: 1.054 ± 0.355
1.054AlaGln: 1.054 ± 0.305
3.373AlaArg: 3.373 ± 0.732
2.319AlaSer: 2.319 ± 0.651
3.163AlaThr: 3.163 ± 0.784
4.849AlaVal: 4.849 ± 1.025
0.422AlaTrp: 0.422 ± 0.223
1.265AlaTyr: 1.265 ± 0.643
0.0AlaXaa: 0.0 ± 0.0
Cys
0.633CysAla: 0.633 ± 0.27
0.211CysCys: 0.211 ± 0.247
0.843CysAsp: 0.843 ± 0.515
1.054CysGlu: 1.054 ± 0.292
1.898CysPhe: 1.898 ± 0.423
0.211CysGly: 0.211 ± 0.244
0.211CysHis: 0.211 ± 0.213
1.054CysIle: 1.054 ± 0.288
1.265CysLys: 1.265 ± 0.539
1.265CysLeu: 1.265 ± 0.256
0.633CysMet: 0.633 ± 0.301
0.633CysAsn: 0.633 ± 0.317
0.843CysPro: 0.843 ± 0.406
0.422CysGln: 0.422 ± 0.445
0.843CysArg: 0.843 ± 0.354
4.006CysSer: 4.006 ± 0.738
0.633CysThr: 0.633 ± 0.243
1.476CysVal: 1.476 ± 0.628
0.0CysTrp: 0.0 ± 0.0
1.265CysTyr: 1.265 ± 0.711
0.0CysXaa: 0.0 ± 0.0
Asp
4.006AspAla: 4.006 ± 0.72
1.265AspCys: 1.265 ± 0.528
5.271AspAsp: 5.271 ± 0.966
3.584AspGlu: 3.584 ± 0.738
4.217AspPhe: 4.217 ± 0.807
4.428AspGly: 4.428 ± 0.881
0.422AspHis: 0.422 ± 0.206
4.638AspIle: 4.638 ± 0.729
4.638AspLys: 4.638 ± 0.949
7.379AspLeu: 7.379 ± 1.785
0.843AspMet: 0.843 ± 0.438
2.741AspAsn: 2.741 ± 0.58
2.53AspPro: 2.53 ± 0.904
1.898AspGln: 1.898 ± 0.516
3.163AspArg: 3.163 ± 0.803
4.849AspSer: 4.849 ± 1.651
2.741AspThr: 2.741 ± 0.817
5.482AspVal: 5.482 ± 0.981
0.422AspTrp: 0.422 ± 0.442
1.898AspTyr: 1.898 ± 0.728
0.0AspXaa: 0.0 ± 0.0
Glu
1.898GluAla: 1.898 ± 0.464
1.265GluCys: 1.265 ± 0.358
3.373GluAsp: 3.373 ± 0.878
4.006GluGlu: 4.006 ± 1.431
2.108GluPhe: 2.108 ± 0.818
3.163GluGly: 3.163 ± 0.657
0.633GluHis: 0.633 ± 0.348
3.795GluIle: 3.795 ± 0.88
6.958GluLys: 6.958 ± 2.078
5.06GluLeu: 5.06 ± 1.186
0.422GluMet: 0.422 ± 0.323
4.006GluAsn: 4.006 ± 0.635
1.687GluPro: 1.687 ± 0.535
0.843GluGln: 0.843 ± 0.445
4.006GluArg: 4.006 ± 0.615
5.06GluSer: 5.06 ± 0.916
2.319GluThr: 2.319 ± 0.45
4.638GluVal: 4.638 ± 1.484
0.633GluTrp: 0.633 ± 0.248
2.53GluTyr: 2.53 ± 0.618
0.0GluXaa: 0.0 ± 0.0
Phe
1.898PheAla: 1.898 ± 0.675
1.265PheCys: 1.265 ± 0.643
4.217PheAsp: 4.217 ± 1.422
3.163PheGlu: 3.163 ± 0.83
1.898PhePhe: 1.898 ± 0.763
2.952PheGly: 2.952 ± 0.585
1.054PheHis: 1.054 ± 0.433
2.108PheIle: 2.108 ± 0.664
4.006PheLys: 4.006 ± 0.727
4.849PheLeu: 4.849 ± 0.542
1.265PheMet: 1.265 ± 0.266
2.741PheAsn: 2.741 ± 0.411
1.265PhePro: 1.265 ± 0.447
0.422PheGln: 0.422 ± 0.305
2.741PheArg: 2.741 ± 0.854
6.114PheSer: 6.114 ± 1.043
2.319PheThr: 2.319 ± 0.531
2.741PheVal: 2.741 ± 0.37
0.211PheTrp: 0.211 ± 0.244
1.476PheTyr: 1.476 ± 0.853
0.0PheXaa: 0.0 ± 0.0
Gly
3.163GlyAla: 3.163 ± 1.315
1.054GlyCys: 1.054 ± 0.442
5.482GlyAsp: 5.482 ± 0.55
3.795GlyGlu: 3.795 ± 1.02
2.108GlyPhe: 2.108 ± 0.629
4.428GlyGly: 4.428 ± 1.011
1.054GlyHis: 1.054 ± 0.383
1.476GlyIle: 1.476 ± 0.46
4.849GlyLys: 4.849 ± 2.075
5.271GlyLeu: 5.271 ± 1.239
1.687GlyMet: 1.687 ± 0.607
2.741GlyAsn: 2.741 ± 0.467
1.898GlyPro: 1.898 ± 0.62
1.687GlyGln: 1.687 ± 0.422
3.373GlyArg: 3.373 ± 0.521
4.217GlySer: 4.217 ± 0.928
2.741GlyThr: 2.741 ± 1.253
4.638GlyVal: 4.638 ± 1.228
0.211GlyTrp: 0.211 ± 0.173
1.265GlyTyr: 1.265 ± 0.677
0.0GlyXaa: 0.0 ± 0.0
His
1.687HisAla: 1.687 ± 0.389
1.265HisCys: 1.265 ± 0.327
0.633HisAsp: 0.633 ± 0.277
0.633HisGlu: 0.633 ± 0.315
0.0HisPhe: 0.0 ± 0.0
0.843HisGly: 0.843 ± 0.642
0.422HisHis: 0.422 ± 0.372
0.843HisIle: 0.843 ± 0.323
1.265HisLys: 1.265 ± 0.441
1.054HisLeu: 1.054 ± 0.44
0.422HisMet: 0.422 ± 0.239
0.633HisAsn: 0.633 ± 0.548
0.633HisPro: 0.633 ± 0.319
0.422HisGln: 0.422 ± 0.313
1.054HisArg: 1.054 ± 0.435
1.476HisSer: 1.476 ± 0.497
1.476HisThr: 1.476 ± 0.466
0.843HisVal: 0.843 ± 0.32
0.211HisTrp: 0.211 ± 0.228
0.422HisTyr: 0.422 ± 0.367
0.0HisXaa: 0.0 ± 0.0
Ile
2.319IleAla: 2.319 ± 0.791
0.422IleCys: 0.422 ± 0.237
3.795IleAsp: 3.795 ± 0.988
2.53IleGlu: 2.53 ± 0.906
1.898IlePhe: 1.898 ± 0.703
2.952IleGly: 2.952 ± 0.491
0.633IleHis: 0.633 ± 0.46
1.687IleIle: 1.687 ± 0.319
4.006IleLys: 4.006 ± 0.727
4.638IleLeu: 4.638 ± 1.011
1.054IleMet: 1.054 ± 0.414
3.163IleAsn: 3.163 ± 0.42
2.53IlePro: 2.53 ± 1.066
2.319IleGln: 2.319 ± 0.958
2.741IleArg: 2.741 ± 0.589
4.006IleSer: 4.006 ± 0.948
2.319IleThr: 2.319 ± 0.908
3.373IleVal: 3.373 ± 0.824
1.265IleTrp: 1.265 ± 0.693
1.476IleTyr: 1.476 ± 0.467
0.0IleXaa: 0.0 ± 0.0
Lys
3.795LysAla: 3.795 ± 1.086
1.265LysCys: 1.265 ± 0.498
3.795LysAsp: 3.795 ± 0.711
3.163LysGlu: 3.163 ± 1.033
3.373LysPhe: 3.373 ± 0.328
4.006LysGly: 4.006 ± 0.776
2.108LysHis: 2.108 ± 0.43
4.428LysIle: 4.428 ± 0.944
4.428LysLys: 4.428 ± 1.009
9.277LysLeu: 9.277 ± 1.287
2.108LysMet: 2.108 ± 0.889
2.952LysAsn: 2.952 ± 0.407
3.584LysPro: 3.584 ± 1.024
2.53LysGln: 2.53 ± 0.557
5.903LysArg: 5.903 ± 1.521
3.373LysSer: 3.373 ± 0.775
4.849LysThr: 4.849 ± 1.097
5.06LysVal: 5.06 ± 1.193
0.633LysTrp: 0.633 ± 0.257
2.952LysTyr: 2.952 ± 0.382
0.0LysXaa: 0.0 ± 0.0
Leu
5.271LeuAla: 5.271 ± 0.781
2.108LeuCys: 2.108 ± 0.49
5.903LeuAsp: 5.903 ± 0.853
6.325LeuGlu: 6.325 ± 0.774
4.428LeuPhe: 4.428 ± 0.904
4.428LeuGly: 4.428 ± 0.631
1.265LeuHis: 1.265 ± 0.327
3.795LeuIle: 3.795 ± 0.686
9.066LeuLys: 9.066 ± 1.442
8.644LeuLeu: 8.644 ± 1.693
2.108LeuMet: 2.108 ± 1.032
4.849LeuAsn: 4.849 ± 1.133
5.271LeuPro: 5.271 ± 0.934
2.53LeuGln: 2.53 ± 0.623
4.428LeuArg: 4.428 ± 0.638
10.12LeuSer: 10.12 ± 2.106
6.114LeuThr: 6.114 ± 1.556
8.223LeuVal: 8.223 ± 1.242
0.211LeuTrp: 0.211 ± 0.247
3.163LeuTyr: 3.163 ± 1.766
0.0LeuXaa: 0.0 ± 0.0
Met
1.476MetAla: 1.476 ± 0.626
0.211MetCys: 0.211 ± 0.153
0.633MetAsp: 0.633 ± 0.267
1.054MetGlu: 1.054 ± 0.43
0.211MetPhe: 0.211 ± 0.247
0.843MetGly: 0.843 ± 0.316
0.211MetHis: 0.211 ± 0.153
1.054MetIle: 1.054 ± 0.607
1.054MetLys: 1.054 ± 0.452
1.687MetLeu: 1.687 ± 0.448
0.422MetMet: 0.422 ± 0.222
1.265MetAsn: 1.265 ± 0.381
0.211MetPro: 0.211 ± 0.211
0.0MetGln: 0.0 ± 0.0
1.265MetArg: 1.265 ± 0.298
2.53MetSer: 2.53 ± 1.237
2.53MetThr: 2.53 ± 1.035
2.741MetVal: 2.741 ± 0.679
0.0MetTrp: 0.0 ± 0.0
1.054MetTyr: 1.054 ± 0.585
0.0MetXaa: 0.0 ± 0.0
Asn
2.53AsnAla: 2.53 ± 1.079
0.211AsnCys: 0.211 ± 0.153
1.687AsnAsp: 1.687 ± 0.418
3.163AsnGlu: 3.163 ± 0.589
4.849AsnPhe: 4.849 ± 0.838
2.108AsnGly: 2.108 ± 0.896
0.633AsnHis: 0.633 ± 0.288
2.53AsnIle: 2.53 ± 0.506
5.482AsnLys: 5.482 ± 1.072
5.482AsnLeu: 5.482 ± 0.958
1.265AsnMet: 1.265 ± 0.35
1.898AsnAsn: 1.898 ± 0.376
1.265AsnPro: 1.265 ± 0.773
1.265AsnGln: 1.265 ± 0.425
1.687AsnArg: 1.687 ± 0.634
4.217AsnSer: 4.217 ± 1.332
4.849AsnThr: 4.849 ± 0.894
4.638AsnVal: 4.638 ± 0.782
0.422AsnTrp: 0.422 ± 0.219
1.898AsnTyr: 1.898 ± 0.619
0.0AsnXaa: 0.0 ± 0.0
Pro
2.319ProAla: 2.319 ± 0.652
0.211ProCys: 0.211 ± 0.153
3.163ProAsp: 3.163 ± 0.662
1.687ProGlu: 1.687 ± 0.591
1.687ProPhe: 1.687 ± 0.568
1.265ProGly: 1.265 ± 0.531
0.422ProHis: 0.422 ± 0.223
1.898ProIle: 1.898 ± 0.471
1.898ProLys: 1.898 ± 0.519
2.741ProLeu: 2.741 ± 0.82
0.633ProMet: 0.633 ± 0.328
2.952ProAsn: 2.952 ± 1.303
1.687ProPro: 1.687 ± 0.839
1.054ProGln: 1.054 ± 0.374
0.633ProArg: 0.633 ± 0.38
4.217ProSer: 4.217 ± 0.611
3.373ProThr: 3.373 ± 0.563
2.741ProVal: 2.741 ± 0.828
0.422ProTrp: 0.422 ± 0.305
2.319ProTyr: 2.319 ± 1.115
0.0ProXaa: 0.0 ± 0.0
Gln
1.054GlnAla: 1.054 ± 0.443
1.054GlnCys: 1.054 ± 0.439
1.898GlnAsp: 1.898 ± 0.797
1.054GlnGlu: 1.054 ± 0.442
1.054GlnPhe: 1.054 ± 0.427
1.687GlnGly: 1.687 ± 0.387
0.0GlnHis: 0.0 ± 0.0
1.898GlnIle: 1.898 ± 0.453
1.476GlnLys: 1.476 ± 0.525
1.898GlnLeu: 1.898 ± 0.513
0.422GlnMet: 0.422 ± 0.32
1.687GlnAsn: 1.687 ± 0.589
0.843GlnPro: 0.843 ± 0.471
0.422GlnGln: 0.422 ± 0.222
1.687GlnArg: 1.687 ± 0.594
1.476GlnSer: 1.476 ± 0.878
1.265GlnThr: 1.265 ± 0.289
1.265GlnVal: 1.265 ± 0.368
0.211GlnTrp: 0.211 ± 0.153
0.843GlnTyr: 0.843 ± 0.32
0.0GlnXaa: 0.0 ± 0.0
Arg
1.898ArgAla: 1.898 ± 0.609
1.265ArgCys: 1.265 ± 0.584
3.373ArgAsp: 3.373 ± 1.154
2.319ArgGlu: 2.319 ± 0.713
2.53ArgPhe: 2.53 ± 0.723
4.006ArgGly: 4.006 ± 0.839
1.054ArgHis: 1.054 ± 0.371
2.108ArgIle: 2.108 ± 0.669
2.741ArgLys: 2.741 ± 0.736
5.903ArgLeu: 5.903 ± 1.053
0.422ArgMet: 0.422 ± 0.292
2.952ArgAsn: 2.952 ± 0.426
1.687ArgPro: 1.687 ± 0.573
0.843ArgGln: 0.843 ± 0.364
4.006ArgArg: 4.006 ± 0.838
4.849ArgSer: 4.849 ± 1.387
4.849ArgThr: 4.849 ± 0.768
3.795ArgVal: 3.795 ± 0.949
0.633ArgTrp: 0.633 ± 0.229
1.898ArgTyr: 1.898 ± 0.749
0.0ArgXaa: 0.0 ± 0.0
Ser
5.06SerAla: 5.06 ± 0.991
0.633SerCys: 0.633 ± 0.317
5.903SerAsp: 5.903 ± 1.022
6.325SerGlu: 6.325 ± 1.267
3.584SerPhe: 3.584 ± 0.687
6.114SerGly: 6.114 ± 1.449
1.898SerHis: 1.898 ± 0.434
5.06SerIle: 5.06 ± 1.213
5.903SerLys: 5.903 ± 1.352
8.433SerLeu: 8.433 ± 1.706
1.476SerMet: 1.476 ± 0.364
4.638SerAsn: 4.638 ± 0.655
1.687SerPro: 1.687 ± 0.58
2.741SerGln: 2.741 ± 0.33
4.638SerArg: 4.638 ± 0.591
13.283SerSer: 13.283 ± 1.515
5.06SerThr: 5.06 ± 0.946
6.114SerVal: 6.114 ± 1.892
0.422SerTrp: 0.422 ± 0.239
2.952SerTyr: 2.952 ± 0.774
0.0SerXaa: 0.0 ± 0.0
Thr
2.952ThrAla: 2.952 ± 0.748
0.633ThrCys: 0.633 ± 0.319
2.741ThrAsp: 2.741 ± 0.606
3.584ThrGlu: 3.584 ± 1.229
3.795ThrPhe: 3.795 ± 0.863
1.898ThrGly: 1.898 ± 0.647
1.265ThrHis: 1.265 ± 0.576
3.373ThrIle: 3.373 ± 1.14
4.006ThrLys: 4.006 ± 0.937
5.693ThrLeu: 5.693 ± 1.281
1.476ThrMet: 1.476 ± 0.492
3.795ThrAsn: 3.795 ± 0.861
2.952ThrPro: 2.952 ± 0.728
0.843ThrGln: 0.843 ± 0.29
1.265ThrArg: 1.265 ± 0.513
5.06ThrSer: 5.06 ± 1.467
4.217ThrThr: 4.217 ± 0.815
6.114ThrVal: 6.114 ± 1.208
0.633ThrTrp: 0.633 ± 0.257
3.373ThrTyr: 3.373 ± 0.496
0.0ThrXaa: 0.0 ± 0.0
Val
4.006ValAla: 4.006 ± 0.829
3.373ValCys: 3.373 ± 0.559
5.903ValAsp: 5.903 ± 1.149
3.795ValGlu: 3.795 ± 0.922
3.373ValPhe: 3.373 ± 0.546
4.217ValGly: 4.217 ± 1.027
1.687ValHis: 1.687 ± 0.802
2.319ValIle: 2.319 ± 0.721
4.638ValLys: 4.638 ± 0.528
8.223ValLeu: 8.223 ± 1.91
2.108ValMet: 2.108 ± 0.628
4.006ValAsn: 4.006 ± 0.561
4.217ValPro: 4.217 ± 0.764
1.265ValGln: 1.265 ± 0.289
4.006ValArg: 4.006 ± 0.666
7.168ValSer: 7.168 ± 1.652
3.584ValThr: 3.584 ± 0.661
7.801ValVal: 7.801 ± 1.533
0.633ValTrp: 0.633 ± 0.622
3.163ValTyr: 3.163 ± 0.704
0.0ValXaa: 0.0 ± 0.0
Trp
0.422TrpAla: 0.422 ± 0.239
0.0TrpCys: 0.0 ± 0.0
0.633TrpAsp: 0.633 ± 0.458
0.422TrpGlu: 0.422 ± 0.249
0.843TrpPhe: 0.843 ± 0.254
0.422TrpGly: 0.422 ± 0.422
0.211TrpHis: 0.211 ± 0.153
0.0TrpIle: 0.0 ± 0.0
0.422TrpLys: 0.422 ± 0.365
1.476TrpLeu: 1.476 ± 0.464
0.211TrpMet: 0.211 ± 0.153
0.422TrpAsn: 0.422 ± 0.307
0.0TrpPro: 0.0 ± 0.0
0.211TrpGln: 0.211 ± 0.219
0.422TrpArg: 0.422 ± 0.355
0.843TrpSer: 0.843 ± 0.315
0.0TrpThr: 0.0 ± 0.0
0.211TrpVal: 0.211 ± 0.173
0.211TrpTrp: 0.211 ± 0.223
0.843TrpTyr: 0.843 ± 0.49
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.476TyrAla: 1.476 ± 0.382
0.633TyrCys: 0.633 ± 0.273
4.006TyrAsp: 4.006 ± 1.124
3.584TyrGlu: 3.584 ± 0.534
2.108TyrPhe: 2.108 ± 0.644
3.373TyrGly: 3.373 ± 0.466
0.422TyrHis: 0.422 ± 0.445
1.687TyrIle: 1.687 ± 0.862
2.319TyrLys: 2.319 ± 0.67
3.163TyrLeu: 3.163 ± 0.544
0.633TyrMet: 0.633 ± 0.458
1.476TyrAsn: 1.476 ± 0.814
1.476TyrPro: 1.476 ± 0.883
0.422TyrGln: 0.422 ± 0.365
1.898TyrArg: 1.898 ± 0.526
2.952TyrSer: 2.952 ± 1.077
1.265TyrThr: 1.265 ± 0.308
2.741TyrVal: 2.741 ± 0.503
0.422TyrTrp: 0.422 ± 0.322
0.422TyrTyr: 0.422 ± 0.219
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (4744 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski