Macaca mulatta (Rhesus macaque)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Mammalia; Theria; Eutheria; Boreoeutheria; Euarchontoglires;

Average proteome isoelectric point is 6.76

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 44415 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|F7FFL7|F7FFL7_MACMU ADAM metallopeptidase with thrombospondin type 1 motif 15 OS=Macaca mulatta OX=9544 GN=ADAMTS15 PE=4 SV=1
MM1 pKa = 8.28DD2 pKa = 4.65ILFAAILAVPLILGQEE18 pKa = 4.32YY19 pKa = 10.42EE20 pKa = 4.16DD21 pKa = 4.06EE22 pKa = 4.14EE23 pKa = 5.45RR24 pKa = 11.84MGEE27 pKa = 3.93DD28 pKa = 3.06EE29 pKa = 4.79YY30 pKa = 11.7YY31 pKa = 10.43QVVYY35 pKa = 10.06YY36 pKa = 7.57YY37 pKa = 10.19TVTPSYY43 pKa = 11.45DD44 pKa = 3.41DD45 pKa = 4.42FSADD49 pKa = 3.3FTIDD53 pKa = 3.3YY54 pKa = 10.76SIFEE58 pKa = 4.24SEE60 pKa = 4.57DD61 pKa = 3.04RR62 pKa = 11.84LNRR65 pKa = 11.84LDD67 pKa = 4.3KK68 pKa = 10.73DD69 pKa = 3.46TTEE72 pKa = 4.3AVGTTISLEE81 pKa = 4.14TARR84 pKa = 11.84ADD86 pKa = 3.42QPKK89 pKa = 9.33PVTVKK94 pKa = 10.46PVTTEE99 pKa = 3.76PQSPDD104 pKa = 3.21LNDD107 pKa = 3.53AVSSLRR113 pKa = 11.84SPIPLLLSCAFVQAGMYY130 pKa = 9.95FMM132 pKa = 6.19

Molecular weight: 14.89 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A5F8AI17|A0A5F8AI17_MACMU Uncharacterized protein OS=Macaca mulatta OX=9544 PE=4 SV=1
MM1 pKa = 7.12FVNRR5 pKa = 11.84GLFHH9 pKa = 7.66RR10 pKa = 11.84DD11 pKa = 3.04LISWGRR17 pKa = 11.84VYY19 pKa = 10.9CNKK22 pKa = 10.34GLFYY26 pKa = 10.82RR27 pKa = 11.84SLLSWWRR34 pKa = 11.84LNISRR39 pKa = 11.84GLLSWWRR46 pKa = 11.84LNISRR51 pKa = 11.84GLLSWWRR58 pKa = 11.84LNISRR63 pKa = 11.84GLLGWWRR70 pKa = 11.84LNISRR75 pKa = 11.84GLLGWWRR82 pKa = 11.84LNISRR87 pKa = 11.84GLLGWWRR94 pKa = 11.84LNISRR99 pKa = 11.84GLVGWWRR106 pKa = 11.84LNISRR111 pKa = 11.84GLVGWWRR118 pKa = 11.84LNISRR123 pKa = 11.84GLLSLWRR130 pKa = 11.84LNISRR135 pKa = 11.84GLLSLWRR142 pKa = 11.84LNISRR147 pKa = 11.84GLLSWWRR154 pKa = 11.84LNFNRR159 pKa = 11.84GLVSWWRR166 pKa = 11.84LNFSRR171 pKa = 11.84GLLSWWRR178 pKa = 11.84LNISRR183 pKa = 11.84GLLSWWRR190 pKa = 11.84LNFNRR195 pKa = 11.84GLVSWWRR202 pKa = 11.84LNFSRR207 pKa = 11.84GLLSWWRR214 pKa = 11.84LNFSRR219 pKa = 11.84GLLSWWRR226 pKa = 11.84LNFSRR231 pKa = 11.84GLLGWWRR238 pKa = 11.84LNFSRR243 pKa = 11.84GLLGWWRR250 pKa = 11.84LNISRR255 pKa = 11.84GLLSWWRR262 pKa = 11.84LNFNRR267 pKa = 11.84GLVSWWRR274 pKa = 11.84LNFSRR279 pKa = 11.84GLLSWWRR286 pKa = 11.84LNFSRR291 pKa = 11.84GLLSWWRR298 pKa = 11.84LNFSRR303 pKa = 11.84GLLGWWRR310 pKa = 11.84LNFSRR315 pKa = 11.84GLLGWWRR322 pKa = 11.84LNFSRR327 pKa = 11.84GLLGWWRR334 pKa = 11.84LNISRR339 pKa = 11.84GLLGWWRR346 pKa = 11.84LNFSRR351 pKa = 11.84GLVSLWRR358 pKa = 11.84LNFSRR363 pKa = 11.84GLVSWWRR370 pKa = 11.84LNFSRR375 pKa = 11.84GLLGWWRR382 pKa = 11.84LNFSRR387 pKa = 11.84GLLGWWRR394 pKa = 11.84LNFSRR399 pKa = 11.84GLLGWWRR406 pKa = 11.84LNFSRR411 pKa = 11.84SLFCRR416 pKa = 11.84SLCSFF421 pKa = 4.8

Molecular weight: 51.96 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

21893

22522

44415

28520000

16

35478

642.1

71.61

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.857 ± 0.012

2.164 ± 0.009

4.814 ± 0.008

7.23 ± 0.017

3.574 ± 0.008

6.39 ± 0.017

2.626 ± 0.007

4.43 ± 0.012

5.953 ± 0.019

9.854 ± 0.016

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.112 ± 0.005

3.686 ± 0.009

6.286 ± 0.018

4.877 ± 0.012

5.637 ± 0.012

8.493 ± 0.014

5.373 ± 0.012

5.871 ± 0.012

1.205 ± 0.004

2.568 ± 0.006
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski