Amino acid dipepetide frequency for Cryphonectria parasitica mycoreovirus 1 (strain 9B21) (CpMYRV-1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.715AlaAla: 3.715 ± 0.622
0.275AlaCys: 0.275 ± 0.177
2.752AlaAsp: 2.752 ± 0.289
2.202AlaGlu: 2.202 ± 0.349
3.715AlaPhe: 3.715 ± 0.571
2.477AlaGly: 2.477 ± 0.939
1.927AlaHis: 1.927 ± 0.438
4.679AlaIle: 4.679 ± 0.505
2.615AlaLys: 2.615 ± 0.712
6.055AlaLeu: 6.055 ± 0.902
2.752AlaMet: 2.752 ± 0.49
2.339AlaAsn: 2.339 ± 0.538
4.541AlaPro: 4.541 ± 0.922
1.927AlaGln: 1.927 ± 0.51
3.44AlaArg: 3.44 ± 0.585
5.504AlaSer: 5.504 ± 1.032
4.816AlaThr: 4.816 ± 0.59
3.44AlaVal: 3.44 ± 0.488
0.55AlaTrp: 0.55 ± 0.26
3.303AlaTyr: 3.303 ± 0.593
0.0AlaXaa: 0.0 ± 0.0
Cys
0.826CysAla: 0.826 ± 0.228
0.275CysCys: 0.275 ± 0.192
1.101CysAsp: 1.101 ± 0.34
0.826CysGlu: 0.826 ± 0.29
0.826CysPhe: 0.826 ± 0.278
0.826CysGly: 0.826 ± 0.393
0.55CysHis: 0.55 ± 0.161
0.275CysIle: 0.275 ± 0.19
0.275CysLys: 0.275 ± 0.248
0.826CysLeu: 0.826 ± 0.288
0.0CysMet: 0.0 ± 0.0
0.55CysAsn: 0.55 ± 0.319
0.963CysPro: 0.963 ± 0.356
0.413CysGln: 0.413 ± 0.189
0.826CysArg: 0.826 ± 0.294
1.101CysSer: 1.101 ± 0.384
0.688CysThr: 0.688 ± 0.278
0.826CysVal: 0.826 ± 0.288
0.138CysTrp: 0.138 ± 0.178
0.275CysTyr: 0.275 ± 0.139
0.0CysXaa: 0.0 ± 0.0
Asp
4.403AspAla: 4.403 ± 0.586
0.688AspCys: 0.688 ± 0.226
3.44AspAsp: 3.44 ± 0.676
2.064AspGlu: 2.064 ± 0.495
2.615AspPhe: 2.615 ± 0.6
2.477AspGly: 2.477 ± 0.356
0.688AspHis: 0.688 ± 0.258
4.403AspIle: 4.403 ± 0.884
1.514AspLys: 1.514 ± 0.313
4.816AspLeu: 4.816 ± 1.036
1.376AspMet: 1.376 ± 0.227
2.339AspAsn: 2.339 ± 0.588
2.615AspPro: 2.615 ± 0.944
2.339AspGln: 2.339 ± 0.642
2.477AspArg: 2.477 ± 0.488
4.816AspSer: 4.816 ± 1.179
2.477AspThr: 2.477 ± 0.548
4.816AspVal: 4.816 ± 0.549
0.826AspTrp: 0.826 ± 0.224
2.89AspTyr: 2.89 ± 0.81
0.0AspXaa: 0.0 ± 0.0
Glu
2.89GluAla: 2.89 ± 0.631
1.101GluCys: 1.101 ± 0.361
2.202GluAsp: 2.202 ± 0.858
0.963GluGlu: 0.963 ± 0.371
1.927GluPhe: 1.927 ± 0.436
1.238GluGly: 1.238 ± 0.453
1.376GluHis: 1.376 ± 0.355
4.128GluIle: 4.128 ± 0.633
1.101GluLys: 1.101 ± 0.439
3.715GluLeu: 3.715 ± 0.754
1.376GluMet: 1.376 ± 0.283
1.101GluAsn: 1.101 ± 0.303
1.789GluPro: 1.789 ± 0.541
2.064GluGln: 2.064 ± 0.501
2.477GluArg: 2.477 ± 0.617
2.752GluSer: 2.752 ± 0.489
2.477GluThr: 2.477 ± 0.538
2.477GluVal: 2.477 ± 0.552
0.413GluTrp: 0.413 ± 0.218
1.927GluTyr: 1.927 ± 0.589
0.0GluXaa: 0.0 ± 0.0
Phe
2.477PheAla: 2.477 ± 0.438
0.826PheCys: 0.826 ± 0.354
3.027PheAsp: 3.027 ± 0.291
1.789PheGlu: 1.789 ± 0.332
1.651PhePhe: 1.651 ± 0.605
3.303PheGly: 3.303 ± 0.644
1.651PheHis: 1.651 ± 0.43
2.064PheIle: 2.064 ± 0.544
0.826PheLys: 0.826 ± 0.333
4.816PheLeu: 4.816 ± 0.649
0.688PheMet: 0.688 ± 0.241
2.615PheAsn: 2.615 ± 0.404
3.027PhePro: 3.027 ± 0.604
1.514PheGln: 1.514 ± 0.315
3.165PheArg: 3.165 ± 0.579
4.541PheSer: 4.541 ± 0.851
2.202PheThr: 2.202 ± 0.672
3.165PheVal: 3.165 ± 0.512
0.138PheTrp: 0.138 ± 0.116
1.651PheTyr: 1.651 ± 0.302
0.0PheXaa: 0.0 ± 0.0
Gly
2.615GlyAla: 2.615 ± 0.707
0.138GlyCys: 0.138 ± 0.116
2.477GlyAsp: 2.477 ± 0.43
1.376GlyGlu: 1.376 ± 0.443
2.339GlyPhe: 2.339 ± 0.771
2.202GlyGly: 2.202 ± 0.473
1.651GlyHis: 1.651 ± 0.498
3.991GlyIle: 3.991 ± 0.617
1.514GlyLys: 1.514 ± 0.506
4.816GlyLeu: 4.816 ± 0.646
2.339GlyMet: 2.339 ± 0.714
2.339GlyAsn: 2.339 ± 0.484
2.064GlyPro: 2.064 ± 0.481
1.376GlyGln: 1.376 ± 0.499
2.339GlyArg: 2.339 ± 0.336
4.266GlySer: 4.266 ± 0.741
3.165GlyThr: 3.165 ± 0.662
5.092GlyVal: 5.092 ± 1.0
0.688GlyTrp: 0.688 ± 0.315
2.202GlyTyr: 2.202 ± 0.481
0.0GlyXaa: 0.0 ± 0.0
His
0.688HisAla: 0.688 ± 0.239
0.275HisCys: 0.275 ± 0.143
2.89HisAsp: 2.89 ± 0.701
0.826HisGlu: 0.826 ± 0.258
1.238HisPhe: 1.238 ± 0.245
2.202HisGly: 2.202 ± 0.631
1.376HisHis: 1.376 ± 0.423
2.339HisIle: 2.339 ± 0.347
0.138HisLys: 0.138 ± 0.116
3.027HisLeu: 3.027 ± 0.655
1.238HisMet: 1.238 ± 0.278
1.514HisAsn: 1.514 ± 0.413
1.927HisPro: 1.927 ± 0.415
0.963HisGln: 0.963 ± 0.384
1.101HisArg: 1.101 ± 0.304
2.752HisSer: 2.752 ± 0.742
2.477HisThr: 2.477 ± 0.529
3.44HisVal: 3.44 ± 0.885
0.413HisTrp: 0.413 ± 0.247
1.789HisTyr: 1.789 ± 0.645
0.0HisXaa: 0.0 ± 0.0
Ile
3.44IleAla: 3.44 ± 0.569
0.413IleCys: 0.413 ± 0.211
5.917IleAsp: 5.917 ± 1.139
3.853IleGlu: 3.853 ± 0.565
3.027IlePhe: 3.027 ± 0.644
3.853IleGly: 3.853 ± 0.595
2.615IleHis: 2.615 ± 0.746
5.504IleIle: 5.504 ± 0.621
2.339IleLys: 2.339 ± 0.622
4.954IleLeu: 4.954 ± 0.875
1.789IleMet: 1.789 ± 0.495
3.578IleAsn: 3.578 ± 0.557
4.816IlePro: 4.816 ± 0.467
3.165IleGln: 3.165 ± 0.672
3.578IleArg: 3.578 ± 0.602
4.679IleSer: 4.679 ± 0.75
5.917IleThr: 5.917 ± 0.771
4.266IleVal: 4.266 ± 0.657
0.413IleTrp: 0.413 ± 0.202
1.651IleTyr: 1.651 ± 0.42
0.0IleXaa: 0.0 ± 0.0
Lys
2.477LysAla: 2.477 ± 0.946
0.688LysCys: 0.688 ± 0.203
1.101LysAsp: 1.101 ± 0.416
0.138LysGlu: 0.138 ± 0.116
1.376LysPhe: 1.376 ± 0.453
1.514LysGly: 1.514 ± 0.776
1.101LysHis: 1.101 ± 0.434
2.064LysIle: 2.064 ± 0.412
1.101LysLys: 1.101 ± 0.37
4.266LysLeu: 4.266 ± 1.001
0.688LysMet: 0.688 ± 0.332
1.789LysAsn: 1.789 ± 0.637
1.651LysPro: 1.651 ± 0.587
1.101LysGln: 1.101 ± 0.372
1.789LysArg: 1.789 ± 0.577
2.339LysSer: 2.339 ± 0.647
2.202LysThr: 2.202 ± 0.633
2.064LysVal: 2.064 ± 0.48
0.413LysTrp: 0.413 ± 0.298
0.963LysTyr: 0.963 ± 0.321
0.0LysXaa: 0.0 ± 0.0
Leu
7.706LeuAla: 7.706 ± 0.941
1.789LeuCys: 1.789 ± 0.575
3.715LeuAsp: 3.715 ± 0.584
4.679LeuGlu: 4.679 ± 0.446
2.89LeuPhe: 2.89 ± 0.55
4.816LeuGly: 4.816 ± 0.732
2.615LeuHis: 2.615 ± 0.551
4.679LeuIle: 4.679 ± 1.11
3.578LeuLys: 3.578 ± 0.989
11.559LeuLeu: 11.559 ± 1.115
1.789LeuMet: 1.789 ± 0.565
4.266LeuAsn: 4.266 ± 0.846
7.431LeuPro: 7.431 ± 1.149
3.303LeuGln: 3.303 ± 0.424
6.88LeuArg: 6.88 ± 0.981
8.669LeuSer: 8.669 ± 0.916
7.293LeuThr: 7.293 ± 1.002
4.403LeuVal: 4.403 ± 0.734
0.413LeuTrp: 0.413 ± 0.32
1.927LeuTyr: 1.927 ± 0.524
0.0LeuXaa: 0.0 ± 0.0
Met
1.514MetAla: 1.514 ± 0.514
0.413MetCys: 0.413 ± 0.224
1.238MetAsp: 1.238 ± 0.319
1.514MetGlu: 1.514 ± 0.543
1.376MetPhe: 1.376 ± 0.464
0.826MetGly: 0.826 ± 0.188
1.238MetHis: 1.238 ± 0.372
2.339MetIle: 2.339 ± 0.657
1.101MetLys: 1.101 ± 0.186
1.376MetLeu: 1.376 ± 0.521
0.963MetMet: 0.963 ± 0.366
0.963MetAsn: 0.963 ± 0.39
0.963MetPro: 0.963 ± 0.36
0.688MetGln: 0.688 ± 0.178
0.963MetArg: 0.963 ± 0.28
2.615MetSer: 2.615 ± 0.678
3.165MetThr: 3.165 ± 0.35
1.514MetVal: 1.514 ± 0.463
0.138MetTrp: 0.138 ± 0.119
1.651MetTyr: 1.651 ± 0.445
0.0MetXaa: 0.0 ± 0.0
Asn
2.89AsnAla: 2.89 ± 0.807
0.688AsnCys: 0.688 ± 0.272
2.339AsnAsp: 2.339 ± 0.814
1.927AsnGlu: 1.927 ± 0.385
1.927AsnPhe: 1.927 ± 0.448
2.752AsnGly: 2.752 ± 0.709
1.514AsnHis: 1.514 ± 0.382
3.165AsnIle: 3.165 ± 0.454
0.963AsnLys: 0.963 ± 0.326
4.679AsnLeu: 4.679 ± 0.999
0.55AsnMet: 0.55 ± 0.328
1.238AsnAsn: 1.238 ± 0.406
3.027AsnPro: 3.027 ± 0.495
1.927AsnGln: 1.927 ± 0.391
1.514AsnArg: 1.514 ± 0.316
3.44AsnSer: 3.44 ± 0.486
3.715AsnThr: 3.715 ± 0.698
4.403AsnVal: 4.403 ± 0.658
0.55AsnTrp: 0.55 ± 0.147
1.238AsnTyr: 1.238 ± 0.42
0.0AsnXaa: 0.0 ± 0.0
Pro
4.816ProAla: 4.816 ± 1.081
0.275ProCys: 0.275 ± 0.232
2.752ProAsp: 2.752 ± 0.4
2.339ProGlu: 2.339 ± 0.623
3.165ProPhe: 3.165 ± 0.583
2.202ProGly: 2.202 ± 0.421
1.376ProHis: 1.376 ± 0.407
3.991ProIle: 3.991 ± 0.699
1.789ProLys: 1.789 ± 0.406
5.78ProLeu: 5.78 ± 0.974
0.963ProMet: 0.963 ± 0.201
2.477ProAsn: 2.477 ± 0.557
4.266ProPro: 4.266 ± 1.693
1.927ProGln: 1.927 ± 0.885
4.266ProArg: 4.266 ± 0.861
6.468ProSer: 6.468 ± 0.917
6.192ProThr: 6.192 ± 1.066
3.991ProVal: 3.991 ± 0.643
0.55ProTrp: 0.55 ± 0.242
3.303ProTyr: 3.303 ± 0.766
0.0ProXaa: 0.0 ± 0.0
Gln
1.789GlnAla: 1.789 ± 0.472
0.413GlnCys: 0.413 ± 0.281
0.963GlnAsp: 0.963 ± 0.35
2.064GlnGlu: 2.064 ± 0.417
1.238GlnPhe: 1.238 ± 0.32
1.101GlnGly: 1.101 ± 0.405
1.514GlnHis: 1.514 ± 0.639
2.064GlnIle: 2.064 ± 0.405
0.963GlnLys: 0.963 ± 0.209
4.266GlnLeu: 4.266 ± 0.8
1.238GlnMet: 1.238 ± 0.497
1.376GlnAsn: 1.376 ± 0.492
2.339GlnPro: 2.339 ± 0.688
1.514GlnGln: 1.514 ± 0.276
1.514GlnArg: 1.514 ± 0.326
3.44GlnSer: 3.44 ± 0.538
3.991GlnThr: 3.991 ± 0.757
1.789GlnVal: 1.789 ± 0.578
0.275GlnTrp: 0.275 ± 0.179
2.202GlnTyr: 2.202 ± 0.323
0.0GlnXaa: 0.0 ± 0.0
Arg
2.339ArgAla: 2.339 ± 0.346
0.688ArgCys: 0.688 ± 0.243
2.752ArgAsp: 2.752 ± 0.809
2.89ArgGlu: 2.89 ± 0.409
2.89ArgPhe: 2.89 ± 0.739
2.477ArgGly: 2.477 ± 0.479
1.927ArgHis: 1.927 ± 0.782
4.266ArgIle: 4.266 ± 0.629
1.651ArgLys: 1.651 ± 0.214
4.541ArgLeu: 4.541 ± 0.875
1.376ArgMet: 1.376 ± 0.462
2.064ArgAsn: 2.064 ± 0.587
3.715ArgPro: 3.715 ± 0.826
1.514ArgGln: 1.514 ± 0.357
2.615ArgArg: 2.615 ± 0.876
3.853ArgSer: 3.853 ± 0.866
4.128ArgThr: 4.128 ± 0.906
6.055ArgVal: 6.055 ± 0.692
0.275ArgTrp: 0.275 ± 0.232
2.615ArgTyr: 2.615 ± 0.418
0.0ArgXaa: 0.0 ± 0.0
Ser
5.78SerAla: 5.78 ± 0.833
0.963SerCys: 0.963 ± 0.437
5.092SerAsp: 5.092 ± 0.939
3.853SerGlu: 3.853 ± 0.661
3.715SerPhe: 3.715 ± 0.666
5.092SerGly: 5.092 ± 0.947
2.339SerHis: 2.339 ± 0.349
5.092SerIle: 5.092 ± 0.833
3.165SerLys: 3.165 ± 0.821
8.945SerLeu: 8.945 ± 1.179
1.789SerMet: 1.789 ± 0.626
4.128SerAsn: 4.128 ± 0.411
4.954SerPro: 4.954 ± 1.138
3.991SerGln: 3.991 ± 0.648
5.78SerArg: 5.78 ± 1.007
7.156SerSer: 7.156 ± 1.081
7.293SerThr: 7.293 ± 0.889
4.679SerVal: 4.679 ± 1.192
0.275SerTrp: 0.275 ± 0.216
4.403SerTyr: 4.403 ± 1.263
0.0SerXaa: 0.0 ± 0.0
Thr
4.816ThrAla: 4.816 ± 0.629
0.826ThrCys: 0.826 ± 0.321
4.403ThrAsp: 4.403 ± 0.88
1.651ThrGlu: 1.651 ± 0.356
3.027ThrPhe: 3.027 ± 0.582
3.853ThrGly: 3.853 ± 0.541
3.44ThrHis: 3.44 ± 0.683
6.605ThrIle: 6.605 ± 1.189
3.027ThrLys: 3.027 ± 0.9
7.018ThrLeu: 7.018 ± 0.77
1.789ThrMet: 1.789 ± 0.642
3.165ThrAsn: 3.165 ± 0.794
4.541ThrPro: 4.541 ± 1.046
2.339ThrGln: 2.339 ± 0.434
3.991ThrArg: 3.991 ± 0.749
8.807ThrSer: 8.807 ± 0.963
6.743ThrThr: 6.743 ± 1.092
5.367ThrVal: 5.367 ± 0.834
0.413ThrTrp: 0.413 ± 0.247
2.615ThrTyr: 2.615 ± 0.327
0.0ThrXaa: 0.0 ± 0.0
Val
3.578ValAla: 3.578 ± 0.429
1.238ValCys: 1.238 ± 0.312
2.202ValAsp: 2.202 ± 0.423
3.027ValGlu: 3.027 ± 0.81
3.578ValPhe: 3.578 ± 0.616
3.715ValGly: 3.715 ± 0.897
2.477ValHis: 2.477 ± 0.424
5.367ValIle: 5.367 ± 0.638
1.651ValLys: 1.651 ± 0.472
4.954ValLeu: 4.954 ± 0.521
1.927ValMet: 1.927 ± 0.472
3.578ValAsn: 3.578 ± 0.782
6.055ValPro: 6.055 ± 1.129
2.615ValGln: 2.615 ± 0.471
3.715ValArg: 3.715 ± 0.586
6.605ValSer: 6.605 ± 1.151
5.504ValThr: 5.504 ± 1.115
5.092ValVal: 5.092 ± 0.744
0.55ValTrp: 0.55 ± 0.256
2.202ValTyr: 2.202 ± 0.318
0.0ValXaa: 0.0 ± 0.0
Trp
0.55TrpAla: 0.55 ± 0.214
0.138TrpCys: 0.138 ± 0.116
0.413TrpAsp: 0.413 ± 0.281
0.0TrpGlu: 0.0 ± 0.0
0.413TrpPhe: 0.413 ± 0.241
0.138TrpGly: 0.138 ± 0.119
0.138TrpHis: 0.138 ± 0.116
0.413TrpIle: 0.413 ± 0.202
0.138TrpLys: 0.138 ± 0.129
0.826TrpLeu: 0.826 ± 0.468
0.55TrpMet: 0.55 ± 0.185
0.413TrpAsn: 0.413 ± 0.171
0.275TrpPro: 0.275 ± 0.138
0.275TrpGln: 0.275 ± 0.155
0.413TrpArg: 0.413 ± 0.233
0.688TrpSer: 0.688 ± 0.23
0.688TrpThr: 0.688 ± 0.292
0.55TrpVal: 0.55 ± 0.364
0.138TrpTrp: 0.138 ± 0.129
0.413TrpTyr: 0.413 ± 0.212
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.715TyrAla: 3.715 ± 0.569
0.275TyrCys: 0.275 ± 0.237
3.303TyrAsp: 3.303 ± 0.638
1.514TyrGlu: 1.514 ± 0.437
2.202TyrPhe: 2.202 ± 0.593
1.927TyrGly: 1.927 ± 0.382
1.101TyrHis: 1.101 ± 0.392
2.339TyrIle: 2.339 ± 0.513
1.376TyrLys: 1.376 ± 0.556
3.165TyrLeu: 3.165 ± 0.592
1.238TyrMet: 1.238 ± 0.315
2.615TyrAsn: 2.615 ± 0.386
1.927TyrPro: 1.927 ± 0.431
1.101TyrGln: 1.101 ± 0.541
1.927TyrArg: 1.927 ± 0.515
3.991TyrSer: 3.991 ± 0.755
3.303TyrThr: 3.303 ± 0.559
2.202TyrVal: 2.202 ± 0.517
0.0TyrTrp: 0.0 ± 0.0
1.376TyrTyr: 1.376 ± 0.51
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 11 proteins (7268 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski