Amino acid dipepetide frequency for Marivirga tractuosa (strain ATCC 23168 / DSM 4126 / NBRC 15989 / NCIMB 1408 / VKM B-1430 / H-43) (Microscilla tractuosa) (Flexibacter tractuosus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.031AlaAla: 4.031 ± 0.084
0.581AlaCys: 0.581 ± 0.025
3.722AlaAsp: 3.722 ± 0.075
4.753AlaGlu: 4.753 ± 0.076
3.395AlaPhe: 3.395 ± 0.056
4.494AlaGly: 4.494 ± 0.074
1.081AlaHis: 1.081 ± 0.028
5.135AlaIle: 5.135 ± 0.072
4.408AlaLys: 4.408 ± 0.074
6.093AlaLeu: 6.093 ± 0.101
1.444AlaMet: 1.444 ± 0.037
3.333AlaAsn: 3.333 ± 0.058
1.945AlaPro: 1.945 ± 0.042
2.56AlaGln: 2.56 ± 0.041
1.98AlaArg: 1.98 ± 0.042
4.109AlaSer: 4.109 ± 0.069
3.189AlaThr: 3.189 ± 0.08
4.05AlaVal: 4.05 ± 0.062
0.607AlaTrp: 0.607 ± 0.021
2.522AlaTyr: 2.522 ± 0.045
0.0AlaXaa: 0.0 ± 0.0
Cys
0.397CysAla: 0.397 ± 0.022
0.085CysCys: 0.085 ± 0.009
0.404CysAsp: 0.404 ± 0.022
0.489CysGlu: 0.489 ± 0.022
0.347CysPhe: 0.347 ± 0.019
0.562CysGly: 0.562 ± 0.024
0.172CysHis: 0.172 ± 0.014
0.468CysIle: 0.468 ± 0.017
0.421CysLys: 0.421 ± 0.018
0.543CysLeu: 0.543 ± 0.022
0.13CysMet: 0.13 ± 0.009
0.346CysAsn: 0.346 ± 0.019
0.32CysPro: 0.32 ± 0.018
0.255CysGln: 0.255 ± 0.015
0.198CysArg: 0.198 ± 0.013
0.5CysSer: 0.5 ± 0.026
0.353CysThr: 0.353 ± 0.02
0.375CysVal: 0.375 ± 0.019
0.068CysTrp: 0.068 ± 0.007
0.24CysTyr: 0.24 ± 0.015
0.0CysXaa: 0.0 ± 0.0
Asp
3.372AspAla: 3.372 ± 0.059
0.385AspCys: 0.385 ± 0.018
2.886AspAsp: 2.886 ± 0.056
4.268AspGlu: 4.268 ± 0.068
3.832AspPhe: 3.832 ± 0.068
3.834AspGly: 3.834 ± 0.1
0.931AspHis: 0.931 ± 0.03
4.435AspIle: 4.435 ± 0.067
4.125AspLys: 4.125 ± 0.067
5.761AspLeu: 5.761 ± 0.082
1.241AspMet: 1.241 ± 0.029
3.001AspAsn: 3.001 ± 0.052
1.942AspPro: 1.942 ± 0.045
2.018AspGln: 2.018 ± 0.041
2.009AspArg: 2.009 ± 0.044
3.642AspSer: 3.642 ± 0.072
2.422AspThr: 2.422 ± 0.056
3.362AspVal: 3.362 ± 0.063
0.774AspTrp: 0.774 ± 0.024
2.853AspTyr: 2.853 ± 0.053
0.0AspXaa: 0.0 ± 0.0
Glu
4.731GluAla: 4.731 ± 0.078
0.339GluCys: 0.339 ± 0.016
4.12GluAsp: 4.12 ± 0.054
6.461GluGlu: 6.461 ± 0.09
3.397GluPhe: 3.397 ± 0.062
4.281GluGly: 4.281 ± 0.061
1.156GluHis: 1.156 ± 0.033
6.155GluIle: 6.155 ± 0.074
6.63GluLys: 6.63 ± 0.107
7.034GluLeu: 7.034 ± 0.086
1.949GluMet: 1.949 ± 0.044
5.305GluAsn: 5.305 ± 0.066
1.767GluPro: 1.767 ± 0.04
2.543GluGln: 2.543 ± 0.046
2.615GluArg: 2.615 ± 0.055
4.202GluSer: 4.202 ± 0.064
3.294GluThr: 3.294 ± 0.054
4.689GluVal: 4.689 ± 0.058
0.792GluTrp: 0.792 ± 0.025
2.707GluTyr: 2.707 ± 0.047
0.0GluXaa: 0.0 ± 0.0
Phe
2.948PheAla: 2.948 ± 0.053
0.381PheCys: 0.381 ± 0.016
3.297PheAsp: 3.297 ± 0.06
3.937PheGlu: 3.937 ± 0.057
2.683PhePhe: 2.683 ± 0.056
3.417PheGly: 3.417 ± 0.057
0.933PheHis: 0.933 ± 0.03
3.964PheIle: 3.964 ± 0.062
3.439PheLys: 3.439 ± 0.061
4.833PheLeu: 4.833 ± 0.081
1.151PheMet: 1.151 ± 0.032
3.318PheAsn: 3.318 ± 0.064
1.786PhePro: 1.786 ± 0.038
2.024PheGln: 2.024 ± 0.048
1.83PheArg: 1.83 ± 0.041
4.198PheSer: 4.198 ± 0.062
3.053PheThr: 3.053 ± 0.064
2.763PheVal: 2.763 ± 0.045
0.604PheTrp: 0.604 ± 0.024
2.345PheTyr: 2.345 ± 0.044
0.0PheXaa: 0.0 ± 0.0
Gly
4.123GlyAla: 4.123 ± 0.065
0.543GlyCys: 0.543 ± 0.036
3.552GlyAsp: 3.552 ± 0.072
4.294GlyGlu: 4.294 ± 0.057
3.653GlyPhe: 3.653 ± 0.057
4.544GlyGly: 4.544 ± 0.085
1.132GlyHis: 1.132 ± 0.032
5.165GlyIle: 5.165 ± 0.076
4.767GlyLys: 4.767 ± 0.075
6.088GlyLeu: 6.088 ± 0.086
1.585GlyMet: 1.585 ± 0.04
3.767GlyAsn: 3.767 ± 0.098
1.379GlyPro: 1.379 ± 0.035
2.116GlyGln: 2.116 ± 0.04
2.243GlyArg: 2.243 ± 0.044
4.169GlySer: 4.169 ± 0.089
3.595GlyThr: 3.595 ± 0.09
4.038GlyVal: 4.038 ± 0.076
0.727GlyTrp: 0.727 ± 0.025
2.685GlyTyr: 2.685 ± 0.05
0.0GlyXaa: 0.0 ± 0.0
His
0.974HisAla: 0.974 ± 0.029
0.157HisCys: 0.157 ± 0.011
0.867HisAsp: 0.867 ± 0.026
1.111HisGlu: 1.111 ± 0.032
1.153HisPhe: 1.153 ± 0.034
1.013HisGly: 1.013 ± 0.032
0.496HisHis: 0.496 ± 0.024
1.342HisIle: 1.342 ± 0.034
1.12HisLys: 1.12 ± 0.03
1.747HisLeu: 1.747 ± 0.037
0.35HisMet: 0.35 ± 0.017
0.869HisAsn: 0.869 ± 0.026
0.921HisPro: 0.921 ± 0.026
0.86HisGln: 0.86 ± 0.027
0.633HisArg: 0.633 ± 0.025
1.088HisSer: 1.088 ± 0.026
0.8HisThr: 0.8 ± 0.026
0.822HisVal: 0.822 ± 0.024
0.216HisTrp: 0.216 ± 0.014
0.841HisTyr: 0.841 ± 0.024
0.0HisXaa: 0.0 ± 0.0
Ile
5.304IleAla: 5.304 ± 0.078
0.618IleCys: 0.618 ± 0.026
4.654IleAsp: 4.654 ± 0.057
5.781IleGlu: 5.781 ± 0.063
3.849IlePhe: 3.849 ± 0.066
5.121IleGly: 5.121 ± 0.076
1.39IleHis: 1.39 ± 0.034
5.951IleIle: 5.951 ± 0.088
5.558IleLys: 5.558 ± 0.083
7.15IleLeu: 7.15 ± 0.103
1.506IleMet: 1.506 ± 0.04
4.714IleAsn: 4.714 ± 0.078
3.21IlePro: 3.21 ± 0.045
2.845IleGln: 2.845 ± 0.047
2.713IleArg: 2.713 ± 0.055
6.193IleSer: 6.193 ± 0.072
4.149IleThr: 4.149 ± 0.073
4.243IleVal: 4.243 ± 0.068
0.748IleTrp: 0.748 ± 0.025
2.96IleTyr: 2.96 ± 0.05
0.0IleXaa: 0.0 ± 0.0
Lys
5.034LysAla: 5.034 ± 0.092
0.332LysCys: 0.332 ± 0.017
4.24LysAsp: 4.24 ± 0.075
6.402LysGlu: 6.402 ± 0.104
2.806LysPhe: 2.806 ± 0.056
4.369LysGly: 4.369 ± 0.067
1.242LysHis: 1.242 ± 0.04
6.011LysIle: 6.011 ± 0.078
6.181LysLys: 6.181 ± 0.09
6.514LysLeu: 6.514 ± 0.097
2.03LysMet: 2.03 ± 0.047
4.573LysAsn: 4.573 ± 0.073
2.356LysPro: 2.356 ± 0.044
2.45LysGln: 2.45 ± 0.056
2.775LysArg: 2.775 ± 0.053
5.027LysSer: 5.027 ± 0.079
3.754LysThr: 3.754 ± 0.052
4.535LysVal: 4.535 ± 0.066
0.819LysTrp: 0.819 ± 0.025
2.758LysTyr: 2.758 ± 0.048
0.0LysXaa: 0.0 ± 0.0
Leu
6.033LeuAla: 6.033 ± 0.08
0.577LeuCys: 0.577 ± 0.021
5.225LeuAsp: 5.225 ± 0.063
6.593LeuGlu: 6.593 ± 0.091
4.823LeuPhe: 4.823 ± 0.075
5.727LeuGly: 5.727 ± 0.071
1.555LeuHis: 1.555 ± 0.036
7.371LeuIle: 7.371 ± 0.107
7.676LeuLys: 7.676 ± 0.116
8.896LeuLeu: 8.896 ± 0.126
2.107LeuMet: 2.107 ± 0.045
5.962LeuAsn: 5.962 ± 0.083
3.485LeuPro: 3.485 ± 0.059
3.223LeuGln: 3.223 ± 0.059
3.264LeuArg: 3.264 ± 0.051
7.303LeuSer: 7.303 ± 0.1
4.684LeuThr: 4.684 ± 0.061
5.345LeuVal: 5.345 ± 0.07
0.886LeuTrp: 0.886 ± 0.031
3.188LeuTyr: 3.188 ± 0.057
0.0LeuXaa: 0.0 ± 0.0
Met
1.718MetAla: 1.718 ± 0.041
0.083MetCys: 0.083 ± 0.008
1.332MetAsp: 1.332 ± 0.029
1.806MetGlu: 1.806 ± 0.039
0.768MetPhe: 0.768 ± 0.031
1.493MetGly: 1.493 ± 0.04
0.437MetHis: 0.437 ± 0.017
1.608MetIle: 1.608 ± 0.041
2.188MetLys: 2.188 ± 0.044
1.9MetLeu: 1.9 ± 0.045
0.717MetMet: 0.717 ± 0.031
1.262MetAsn: 1.262 ± 0.032
0.863MetPro: 0.863 ± 0.026
0.893MetGln: 0.893 ± 0.027
0.958MetArg: 0.958 ± 0.029
1.439MetSer: 1.439 ± 0.033
1.09MetThr: 1.09 ± 0.027
1.368MetVal: 1.368 ± 0.032
0.162MetTrp: 0.162 ± 0.011
0.584MetTyr: 0.584 ± 0.022
0.0MetXaa: 0.0 ± 0.0
Asn
3.603AsnAla: 3.603 ± 0.062
0.437AsnCys: 0.437 ± 0.028
3.175AsnAsp: 3.175 ± 0.059
4.157AsnGlu: 4.157 ± 0.063
3.115AsnPhe: 3.115 ± 0.062
3.882AsnGly: 3.882 ± 0.098
1.048AsnHis: 1.048 ± 0.028
4.719AsnIle: 4.719 ± 0.067
3.948AsnLys: 3.948 ± 0.058
5.619AsnLeu: 5.619 ± 0.077
1.236AsnMet: 1.236 ± 0.032
3.464AsnAsn: 3.464 ± 0.079
2.739AsnPro: 2.739 ± 0.056
2.651AsnGln: 2.651 ± 0.053
2.29AsnArg: 2.29 ± 0.048
4.168AsnSer: 4.168 ± 0.074
3.12AsnThr: 3.12 ± 0.069
3.183AsnVal: 3.183 ± 0.058
0.786AsnTrp: 0.786 ± 0.028
2.734AsnTyr: 2.734 ± 0.052
0.0AsnXaa: 0.0 ± 0.0
Pro
2.053ProAla: 2.053 ± 0.047
0.187ProCys: 0.187 ± 0.013
2.339ProAsp: 2.339 ± 0.048
3.015ProGlu: 3.015 ± 0.051
1.931ProPhe: 1.931 ± 0.037
1.93ProGly: 1.93 ± 0.046
0.594ProHis: 0.594 ± 0.022
2.728ProIle: 2.728 ± 0.044
2.341ProLys: 2.341 ± 0.048
2.899ProLeu: 2.899 ± 0.05
0.668ProMet: 0.668 ± 0.024
2.114ProAsn: 2.114 ± 0.054
0.852ProPro: 0.852 ± 0.029
1.198ProGln: 1.198 ± 0.028
0.87ProArg: 0.87 ± 0.025
2.154ProSer: 2.154 ± 0.039
1.795ProThr: 1.795 ± 0.049
2.24ProVal: 2.24 ± 0.042
0.307ProTrp: 0.307 ± 0.016
1.409ProTyr: 1.409 ± 0.036
0.0ProXaa: 0.0 ± 0.0
Gln
2.283GlnAla: 2.283 ± 0.047
0.157GlnCys: 0.157 ± 0.012
1.943GlnAsp: 1.943 ± 0.042
2.866GlnGlu: 2.866 ± 0.05
1.944GlnPhe: 1.944 ± 0.044
1.83GlnGly: 1.83 ± 0.042
0.65GlnHis: 0.65 ± 0.023
2.776GlnIle: 2.776 ± 0.047
3.136GlnLys: 3.136 ± 0.061
3.736GlnLeu: 3.736 ± 0.069
0.869GlnMet: 0.869 ± 0.026
2.512GlnAsn: 2.512 ± 0.051
1.108GlnPro: 1.108 ± 0.03
1.579GlnGln: 1.579 ± 0.041
1.239GlnArg: 1.239 ± 0.03
2.438GlnSer: 2.438 ± 0.048
1.662GlnThr: 1.662 ± 0.037
2.021GlnVal: 2.021 ± 0.04
0.431GlnTrp: 0.431 ± 0.017
1.535GlnTyr: 1.535 ± 0.034
0.0GlnXaa: 0.0 ± 0.0
Arg
2.018ArgAla: 2.018 ± 0.044
0.159ArgCys: 0.159 ± 0.012
1.861ArgAsp: 1.861 ± 0.038
2.329ArgGlu: 2.329 ± 0.052
1.922ArgPhe: 1.922 ± 0.042
1.907ArgGly: 1.907 ± 0.047
0.582ArgHis: 0.582 ± 0.022
2.951ArgIle: 2.951 ± 0.053
3.005ArgLys: 3.005 ± 0.063
3.333ArgLeu: 3.333 ± 0.062
0.962ArgMet: 0.962 ± 0.026
2.298ArgAsn: 2.298 ± 0.048
1.117ArgPro: 1.117 ± 0.031
1.253ArgGln: 1.253 ± 0.037
1.311ArgArg: 1.311 ± 0.029
2.036ArgSer: 2.036 ± 0.046
1.743ArgThr: 1.743 ± 0.04
2.015ArgVal: 2.015 ± 0.041
0.399ArgTrp: 0.399 ± 0.019
1.54ArgTyr: 1.54 ± 0.035
0.0ArgXaa: 0.0 ± 0.0
Ser
4.272SerAla: 4.272 ± 0.081
0.538SerCys: 0.538 ± 0.022
3.721SerAsp: 3.721 ± 0.061
4.52SerGlu: 4.52 ± 0.066
4.163SerPhe: 4.163 ± 0.064
5.042SerGly: 5.042 ± 0.096
1.115SerHis: 1.115 ± 0.028
5.937SerIle: 5.937 ± 0.074
4.564SerLys: 4.564 ± 0.066
6.612SerLeu: 6.612 ± 0.074
1.451SerMet: 1.451 ± 0.037
4.004SerAsn: 4.004 ± 0.077
2.205SerPro: 2.205 ± 0.046
2.323SerGln: 2.323 ± 0.047
2.194SerArg: 2.194 ± 0.045
4.861SerSer: 4.861 ± 0.096
3.593SerThr: 3.593 ± 0.073
3.993SerVal: 3.993 ± 0.068
0.753SerTrp: 0.753 ± 0.03
2.754SerTyr: 2.754 ± 0.056
0.0SerXaa: 0.0 ± 0.0
Thr
3.676ThrAla: 3.676 ± 0.073
0.3ThrCys: 0.3 ± 0.016
3.069ThrAsp: 3.069 ± 0.059
3.595ThrGlu: 3.595 ± 0.056
2.695ThrPhe: 2.695 ± 0.058
3.803ThrGly: 3.803 ± 0.067
0.869ThrHis: 0.869 ± 0.029
4.165ThrIle: 4.165 ± 0.077
3.026ThrLys: 3.026 ± 0.054
4.666ThrLeu: 4.666 ± 0.072
0.841ThrMet: 0.841 ± 0.028
2.737ThrAsn: 2.737 ± 0.068
1.923ThrPro: 1.923 ± 0.052
1.672ThrGln: 1.672 ± 0.034
1.472ThrArg: 1.472 ± 0.036
3.292ThrSer: 3.292 ± 0.071
2.806ThrThr: 2.806 ± 0.077
3.476ThrVal: 3.476 ± 0.093
0.5ThrTrp: 0.5 ± 0.023
2.089ThrTyr: 2.089 ± 0.051
0.0ThrXaa: 0.0 ± 0.0
Val
3.88ValAla: 3.88 ± 0.067
0.446ValCys: 0.446 ± 0.024
3.488ValAsp: 3.488 ± 0.064
4.263ValGlu: 4.263 ± 0.061
3.26ValPhe: 3.26 ± 0.057
3.716ValGly: 3.716 ± 0.068
0.961ValHis: 0.961 ± 0.03
4.496ValIle: 4.496 ± 0.077
4.223ValLys: 4.223 ± 0.06
5.565ValLeu: 5.565 ± 0.074
1.352ValMet: 1.352 ± 0.041
3.536ValAsn: 3.536 ± 0.061
2.033ValPro: 2.033 ± 0.04
1.867ValGln: 1.867 ± 0.041
2.068ValArg: 2.068 ± 0.043
4.286ValSer: 4.286 ± 0.074
3.025ValThr: 3.025 ± 0.08
3.857ValVal: 3.857 ± 0.061
0.579ValTrp: 0.579 ± 0.023
2.237ValTyr: 2.237 ± 0.04
0.0ValXaa: 0.0 ± 0.0
Trp
0.61TrpAla: 0.61 ± 0.025
0.079TrpCys: 0.079 ± 0.007
0.724TrpAsp: 0.724 ± 0.039
0.785TrpGlu: 0.785 ± 0.029
0.55TrpPhe: 0.55 ± 0.023
0.656TrpGly: 0.656 ± 0.025
0.213TrpHis: 0.213 ± 0.014
0.735TrpIle: 0.735 ± 0.027
0.804TrpLys: 0.804 ± 0.025
1.027TrpLeu: 1.027 ± 0.03
0.323TrpMet: 0.323 ± 0.015
0.681TrpAsn: 0.681 ± 0.027
0.258TrpPro: 0.258 ± 0.014
0.461TrpGln: 0.461 ± 0.018
0.41TrpArg: 0.41 ± 0.018
0.696TrpSer: 0.696 ± 0.023
0.543TrpThr: 0.543 ± 0.025
0.678TrpVal: 0.678 ± 0.024
0.148TrpTrp: 0.148 ± 0.011
0.427TrpTyr: 0.427 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.373TyrAla: 2.373 ± 0.046
0.288TyrCys: 0.288 ± 0.015
2.474TyrAsp: 2.474 ± 0.047
2.74TyrGlu: 2.74 ± 0.052
2.617TyrPhe: 2.617 ± 0.051
2.545TyrGly: 2.545 ± 0.047
0.824TyrHis: 0.824 ± 0.027
2.545TyrIle: 2.545 ± 0.046
2.651TyrLys: 2.651 ± 0.05
3.906TyrLeu: 3.906 ± 0.058
0.757TyrMet: 0.757 ± 0.021
2.281TyrAsn: 2.281 ± 0.053
1.415TyrPro: 1.415 ± 0.033
1.924TyrGln: 1.924 ± 0.04
1.667TyrArg: 1.667 ± 0.039
2.816TyrSer: 2.816 ± 0.051
2.002TyrThr: 2.002 ± 0.054
2.083TyrVal: 2.083 ± 0.037
0.5TyrTrp: 0.5 ± 0.021
1.937TyrTyr: 1.937 ± 0.048
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3748 proteins (1335281 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski