Amino acid dipepetide frequency for Penicillium stoloniferum virus F

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.18AlaAla: 4.18 ± 1.866
0.0AlaCys: 0.0 ± 0.0
5.225AlaAsp: 5.225 ± 4.204
0.0AlaGlu: 0.0 ± 0.0
6.27AlaPhe: 6.27 ± 3.937
5.225AlaGly: 5.225 ± 2.707
2.09AlaHis: 2.09 ± 0.185
0.0AlaIle: 0.0 ± 0.0
7.315AlaLys: 7.315 ± 0.102
7.315AlaLeu: 7.315 ± 1.394
1.045AlaMet: 1.045 ± 0.656
2.09AlaAsn: 2.09 ± 0.185
1.045AlaPro: 1.045 ± 0.841
4.18AlaGln: 4.18 ± 3.363
8.359AlaArg: 8.359 ± 2.235
8.359AlaSer: 8.359 ± 0.759
2.09AlaThr: 2.09 ± 0.185
4.18AlaVal: 4.18 ± 0.369
1.045AlaTrp: 1.045 ± 0.656
3.135AlaTyr: 3.135 ± 0.472
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.045CysAsp: 1.045 ± 0.656
1.045CysGlu: 1.045 ± 0.656
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
2.09CysAsn: 2.09 ± 1.312
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.045CysSer: 1.045 ± 0.841
1.045CysThr: 1.045 ± 0.656
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.045CysTyr: 1.045 ± 0.656
0.0CysXaa: 0.0 ± 0.0
Asp
7.315AspAla: 7.315 ± 2.891
1.045AspCys: 1.045 ± 0.841
4.18AspAsp: 4.18 ± 0.369
6.27AspGlu: 6.27 ± 0.554
2.09AspPhe: 2.09 ± 1.682
4.18AspGly: 4.18 ± 1.128
3.135AspHis: 3.135 ± 1.025
2.09AspIle: 2.09 ± 0.185
4.18AspLys: 4.18 ± 0.369
5.225AspLeu: 5.225 ± 0.287
2.09AspMet: 2.09 ± 0.44
3.135AspAsn: 3.135 ± 1.025
3.135AspPro: 3.135 ± 0.472
3.135AspGln: 3.135 ± 2.522
5.225AspArg: 5.225 ± 0.287
5.225AspSer: 5.225 ± 1.784
3.135AspThr: 3.135 ± 1.025
6.27AspVal: 6.27 ± 0.943
1.045AspTrp: 1.045 ± 0.656
3.135AspTyr: 3.135 ± 0.472
0.0AspXaa: 0.0 ± 0.0
Glu
3.135GluAla: 3.135 ± 1.969
1.045GluCys: 1.045 ± 0.656
3.135GluAsp: 3.135 ± 1.025
2.09GluGlu: 2.09 ± 1.312
2.09GluPhe: 2.09 ± 1.312
3.135GluGly: 3.135 ± 0.472
2.09GluHis: 2.09 ± 1.312
5.225GluIle: 5.225 ± 0.287
5.225GluLys: 5.225 ± 0.287
5.225GluLeu: 5.225 ± 1.21
1.045GluMet: 1.045 ± 0.656
1.045GluAsn: 1.045 ± 0.841
1.045GluPro: 1.045 ± 0.841
3.135GluGln: 3.135 ± 1.969
3.135GluArg: 3.135 ± 1.969
2.09GluSer: 2.09 ± 1.682
6.27GluThr: 6.27 ± 0.554
4.18GluVal: 4.18 ± 1.128
1.045GluTrp: 1.045 ± 0.656
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
4.18PheAla: 4.18 ± 0.369
0.0PheCys: 0.0 ± 0.0
7.315PheAsp: 7.315 ± 4.593
3.135PheGlu: 3.135 ± 1.025
3.135PhePhe: 3.135 ± 0.472
3.135PheGly: 3.135 ± 1.969
3.135PheHis: 3.135 ± 1.969
1.045PheIle: 1.045 ± 0.656
6.27PheLys: 6.27 ± 2.051
5.225PheLeu: 5.225 ± 3.281
0.0PheMet: 0.0 ± 0.0
1.045PheAsn: 1.045 ± 0.841
6.27PhePro: 6.27 ± 0.554
1.045PheGln: 1.045 ± 0.656
4.18PheArg: 4.18 ± 1.128
6.27PheSer: 6.27 ± 0.554
4.18PheThr: 4.18 ± 2.625
4.18PheVal: 4.18 ± 2.625
1.045PheTrp: 1.045 ± 0.656
2.09PheTyr: 2.09 ± 0.185
0.0PheXaa: 0.0 ± 0.0
Gly
4.18GlyAla: 4.18 ± 1.866
1.045GlyCys: 1.045 ± 0.656
6.27GlyAsp: 6.27 ± 0.554
2.09GlyGlu: 2.09 ± 0.185
5.225GlyPhe: 5.225 ± 3.281
2.09GlyGly: 2.09 ± 1.312
3.135GlyHis: 3.135 ± 1.025
2.09GlyIle: 2.09 ± 0.185
3.135GlyLys: 3.135 ± 1.969
5.225GlyLeu: 5.225 ± 0.287
1.045GlyMet: 1.045 ± 0.841
2.09GlyAsn: 2.09 ± 0.185
1.045GlyPro: 1.045 ± 0.841
0.0GlyGln: 0.0 ± 0.0
2.09GlyArg: 2.09 ± 1.312
3.135GlySer: 3.135 ± 1.969
2.09GlyThr: 2.09 ± 1.682
3.135GlyVal: 3.135 ± 1.025
1.045GlyTrp: 1.045 ± 0.841
4.18GlyTyr: 4.18 ± 1.866
0.0GlyXaa: 0.0 ± 0.0
His
1.045HisAla: 1.045 ± 0.656
0.0HisCys: 0.0 ± 0.0
4.18HisAsp: 4.18 ± 1.128
2.09HisGlu: 2.09 ± 0.185
2.09HisPhe: 2.09 ± 1.312
1.045HisGly: 1.045 ± 0.656
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.045HisLys: 1.045 ± 0.656
1.045HisLeu: 1.045 ± 0.656
3.135HisMet: 3.135 ± 1.025
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
1.045HisArg: 1.045 ± 0.656
2.09HisSer: 2.09 ± 0.185
1.045HisThr: 1.045 ± 0.656
2.09HisVal: 2.09 ± 0.185
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.18IleAla: 4.18 ± 0.369
0.0IleCys: 0.0 ± 0.0
5.225IleAsp: 5.225 ± 0.287
0.0IleGlu: 0.0 ± 0.0
2.09IlePhe: 2.09 ± 1.682
3.135IleGly: 3.135 ± 1.025
0.0IleHis: 0.0 ± 0.0
2.09IleIle: 2.09 ± 0.185
2.09IleLys: 2.09 ± 0.185
1.045IleLeu: 1.045 ± 0.656
2.09IleMet: 2.09 ± 1.312
1.045IleAsn: 1.045 ± 0.841
6.27IlePro: 6.27 ± 0.554
1.045IleGln: 1.045 ± 0.841
0.0IleArg: 0.0 ± 0.0
4.18IleSer: 4.18 ± 0.369
0.0IleThr: 0.0 ± 0.0
1.045IleVal: 1.045 ± 0.656
0.0IleTrp: 0.0 ± 0.0
2.09IleTyr: 2.09 ± 0.185
0.0IleXaa: 0.0 ± 0.0
Lys
6.27LysAla: 6.27 ± 0.554
0.0LysCys: 0.0 ± 0.0
1.045LysAsp: 1.045 ± 0.841
3.135LysGlu: 3.135 ± 0.472
7.315LysPhe: 7.315 ± 1.599
0.0LysGly: 0.0 ± 0.0
0.0LysHis: 0.0 ± 0.0
2.09LysIle: 2.09 ± 0.185
9.404LysLys: 9.404 ± 4.409
7.315LysLeu: 7.315 ± 1.599
1.045LysMet: 1.045 ± 0.841
1.045LysAsn: 1.045 ± 0.656
5.225LysPro: 5.225 ± 0.287
3.135LysGln: 3.135 ± 0.472
4.18LysArg: 4.18 ± 1.866
3.135LysSer: 3.135 ± 0.472
8.359LysThr: 8.359 ± 0.759
6.27LysVal: 6.27 ± 0.943
2.09LysTrp: 2.09 ± 0.185
1.045LysTyr: 1.045 ± 0.656
0.0LysXaa: 0.0 ± 0.0
Leu
6.27LeuAla: 6.27 ± 0.943
0.0LeuCys: 0.0 ± 0.0
8.359LeuAsp: 8.359 ± 0.738
5.225LeuGlu: 5.225 ± 1.784
4.18LeuPhe: 4.18 ± 1.866
9.404LeuGly: 9.404 ± 1.415
2.09LeuHis: 2.09 ± 1.312
2.09LeuIle: 2.09 ± 1.312
7.315LeuLys: 7.315 ± 3.096
5.225LeuLeu: 5.225 ± 1.21
2.09LeuMet: 2.09 ± 0.185
1.045LeuAsn: 1.045 ± 0.841
8.359LeuPro: 8.359 ± 0.738
1.045LeuGln: 1.045 ± 0.841
4.18LeuArg: 4.18 ± 0.369
10.449LeuSer: 10.449 ± 2.071
6.27LeuThr: 6.27 ± 0.554
4.18LeuVal: 4.18 ± 3.363
1.045LeuTrp: 1.045 ± 0.656
4.18LeuTyr: 4.18 ± 0.369
0.0LeuXaa: 0.0 ± 0.0
Met
3.135MetAla: 3.135 ± 0.472
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.045MetGlu: 1.045 ± 0.656
1.045MetPhe: 1.045 ± 0.656
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.045MetIle: 1.045 ± 0.841
2.09MetLys: 2.09 ± 0.185
2.09MetLeu: 2.09 ± 0.185
0.0MetMet: 0.0 ± 0.0
1.045MetAsn: 1.045 ± 0.656
1.045MetPro: 1.045 ± 0.841
1.045MetGln: 1.045 ± 0.656
1.045MetArg: 1.045 ± 0.841
5.225MetSer: 5.225 ± 2.707
1.045MetThr: 1.045 ± 0.656
2.09MetVal: 2.09 ± 0.185
0.0MetTrp: 0.0 ± 0.0
1.045MetTyr: 1.045 ± 0.656
0.0MetXaa: 0.0 ± 0.0
Asn
3.135AsnAla: 3.135 ± 0.472
0.0AsnCys: 0.0 ± 0.0
3.135AsnAsp: 3.135 ± 1.025
1.045AsnGlu: 1.045 ± 0.656
1.045AsnPhe: 1.045 ± 0.656
1.045AsnGly: 1.045 ± 0.656
0.0AsnHis: 0.0 ± 0.0
2.09AsnIle: 2.09 ± 1.682
2.09AsnLys: 2.09 ± 0.185
3.135AsnLeu: 3.135 ± 1.025
0.0AsnMet: 0.0 ± 0.0
0.0AsnAsn: 0.0 ± 0.0
1.045AsnPro: 1.045 ± 0.841
2.09AsnGln: 2.09 ± 1.682
0.0AsnArg: 0.0 ± 0.0
3.135AsnSer: 3.135 ± 2.522
2.09AsnThr: 2.09 ± 0.185
4.18AsnVal: 4.18 ± 1.128
1.045AsnTrp: 1.045 ± 0.656
2.09AsnTyr: 2.09 ± 1.312
0.0AsnXaa: 0.0 ± 0.0
Pro
4.18ProAla: 4.18 ± 1.866
0.0ProCys: 0.0 ± 0.0
5.225ProAsp: 5.225 ± 0.287
4.18ProGlu: 4.18 ± 1.128
7.315ProPhe: 7.315 ± 3.096
3.135ProGly: 3.135 ± 0.472
2.09ProHis: 2.09 ± 0.185
1.045ProIle: 1.045 ± 0.841
2.09ProLys: 2.09 ± 1.682
6.27ProLeu: 6.27 ± 2.051
0.0ProMet: 0.0 ± 0.0
4.18ProAsn: 4.18 ± 1.866
3.135ProPro: 3.135 ± 1.025
3.135ProGln: 3.135 ± 1.025
1.045ProArg: 1.045 ± 0.841
2.09ProSer: 2.09 ± 0.185
0.0ProThr: 0.0 ± 0.0
0.0ProVal: 0.0 ± 0.0
0.0ProTrp: 0.0 ± 0.0
2.09ProTyr: 2.09 ± 1.312
0.0ProXaa: 0.0 ± 0.0
Gln
1.045GlnAla: 1.045 ± 0.841
1.045GlnCys: 1.045 ± 0.656
1.045GlnAsp: 1.045 ± 0.656
0.0GlnGlu: 0.0 ± 0.0
3.135GlnPhe: 3.135 ± 2.522
2.09GlnGly: 2.09 ± 0.185
0.0GlnHis: 0.0 ± 0.0
1.045GlnIle: 1.045 ± 0.656
1.045GlnLys: 1.045 ± 0.656
5.225GlnLeu: 5.225 ± 4.204
1.045GlnMet: 1.045 ± 0.841
1.045GlnAsn: 1.045 ± 0.656
1.045GlnPro: 1.045 ± 0.841
1.045GlnGln: 1.045 ± 0.656
3.135GlnArg: 3.135 ± 0.472
3.135GlnSer: 3.135 ± 1.025
3.135GlnThr: 3.135 ± 1.025
2.09GlnVal: 2.09 ± 0.185
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
2.09ArgAla: 2.09 ± 0.185
0.0ArgCys: 0.0 ± 0.0
2.09ArgAsp: 2.09 ± 0.185
2.09ArgGlu: 2.09 ± 0.185
2.09ArgPhe: 2.09 ± 1.312
3.135ArgGly: 3.135 ± 0.472
1.045ArgHis: 1.045 ± 0.656
3.135ArgIle: 3.135 ± 0.472
3.135ArgLys: 3.135 ± 1.969
8.359ArgLeu: 8.359 ± 2.256
1.045ArgMet: 1.045 ± 0.656
2.09ArgAsn: 2.09 ± 1.682
2.09ArgPro: 2.09 ± 1.682
2.09ArgGln: 2.09 ± 1.682
1.045ArgArg: 1.045 ± 0.656
4.18ArgSer: 4.18 ± 1.128
1.045ArgThr: 1.045 ± 0.656
5.225ArgVal: 5.225 ± 1.21
2.09ArgTrp: 2.09 ± 0.185
4.18ArgTyr: 4.18 ± 0.369
0.0ArgXaa: 0.0 ± 0.0
Ser
5.225SerAla: 5.225 ± 1.21
1.045SerCys: 1.045 ± 0.656
5.225SerAsp: 5.225 ± 2.707
7.315SerGlu: 7.315 ± 0.102
8.359SerPhe: 8.359 ± 0.738
3.135SerGly: 3.135 ± 0.472
1.045SerHis: 1.045 ± 0.656
6.27SerIle: 6.27 ± 2.051
4.18SerLys: 4.18 ± 1.866
6.27SerLeu: 6.27 ± 0.554
5.225SerMet: 5.225 ± 0.287
3.135SerAsn: 3.135 ± 0.472
2.09SerPro: 2.09 ± 0.185
1.045SerGln: 1.045 ± 0.841
4.18SerArg: 4.18 ± 1.128
4.18SerSer: 4.18 ± 0.369
5.225SerThr: 5.225 ± 1.21
4.18SerVal: 4.18 ± 0.369
1.045SerTrp: 1.045 ± 0.656
1.045SerTyr: 1.045 ± 0.656
0.0SerXaa: 0.0 ± 0.0
Thr
4.18ThrAla: 4.18 ± 3.363
0.0ThrCys: 0.0 ± 0.0
5.225ThrAsp: 5.225 ± 1.21
2.09ThrGlu: 2.09 ± 1.312
2.09ThrPhe: 2.09 ± 1.312
2.09ThrGly: 2.09 ± 1.682
0.0ThrHis: 0.0 ± 0.0
3.135ThrIle: 3.135 ± 1.025
4.18ThrLys: 4.18 ± 0.369
6.27ThrLeu: 6.27 ± 2.44
2.09ThrMet: 2.09 ± 1.682
1.045ThrAsn: 1.045 ± 0.656
3.135ThrPro: 3.135 ± 0.472
2.09ThrGln: 2.09 ± 1.312
6.27ThrArg: 6.27 ± 2.44
4.18ThrSer: 4.18 ± 1.866
6.27ThrThr: 6.27 ± 0.554
2.09ThrVal: 2.09 ± 1.682
1.045ThrTrp: 1.045 ± 0.841
2.09ThrTyr: 2.09 ± 1.312
0.0ThrXaa: 0.0 ± 0.0
Val
4.18ValAla: 4.18 ± 1.128
1.045ValCys: 1.045 ± 0.656
3.135ValAsp: 3.135 ± 1.025
8.359ValGlu: 8.359 ± 0.759
5.225ValPhe: 5.225 ± 3.281
4.18ValGly: 4.18 ± 3.363
1.045ValHis: 1.045 ± 0.656
0.0ValIle: 0.0 ± 0.0
4.18ValLys: 4.18 ± 0.369
6.27ValLeu: 6.27 ± 0.554
0.0ValMet: 0.0 ± 0.0
2.09ValAsn: 2.09 ± 0.185
3.135ValPro: 3.135 ± 1.969
0.0ValGln: 0.0 ± 0.0
1.045ValArg: 1.045 ± 0.656
3.135ValSer: 3.135 ± 1.025
5.225ValThr: 5.225 ± 1.21
1.045ValVal: 1.045 ± 0.656
2.09ValTrp: 2.09 ± 0.185
3.135ValTyr: 3.135 ± 1.025
0.0ValXaa: 0.0 ± 0.0
Trp
2.09TrpAla: 2.09 ± 0.185
0.0TrpCys: 0.0 ± 0.0
1.045TrpAsp: 1.045 ± 0.656
1.045TrpGlu: 1.045 ± 0.656
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
1.045TrpIle: 1.045 ± 0.841
0.0TrpLys: 0.0 ± 0.0
2.09TrpLeu: 2.09 ± 1.312
0.0TrpMet: 0.0 ± 0.498
2.09TrpAsn: 2.09 ± 0.185
0.0TrpPro: 0.0 ± 0.0
1.045TrpGln: 1.045 ± 0.841
1.045TrpArg: 1.045 ± 0.841
1.045TrpSer: 1.045 ± 0.656
0.0TrpThr: 0.0 ± 0.0
2.09TrpVal: 2.09 ± 1.312
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.135TyrAla: 3.135 ± 1.025
1.045TyrCys: 1.045 ± 0.656
3.135TyrAsp: 3.135 ± 1.025
3.135TyrGlu: 3.135 ± 0.472
2.09TyrPhe: 2.09 ± 1.312
4.18TyrGly: 4.18 ± 0.369
1.045TyrHis: 1.045 ± 0.656
2.09TyrIle: 2.09 ± 1.312
3.135TyrLys: 3.135 ± 1.969
4.18TyrLeu: 4.18 ± 1.128
0.0TyrMet: 0.0 ± 0.0
1.045TyrAsn: 1.045 ± 0.656
2.09TyrPro: 2.09 ± 1.312
1.045TyrGln: 1.045 ± 0.656
1.045TyrArg: 1.045 ± 0.841
3.135TyrSer: 3.135 ± 2.522
1.045TyrThr: 1.045 ± 0.841
0.0TyrVal: 0.0 ± 0.0
0.0TyrTrp: 0.0 ± 0.0
3.135TyrTyr: 3.135 ± 1.025
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (958 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski