Amino acid dipepetide frequency for Mosquito VEM Anellovirus SDBVL B

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.021AlaAla: 8.021 ± 6.862
0.0AlaCys: 0.0 ± 0.0
1.337AlaAsp: 1.337 ± 1.208
2.674AlaGlu: 2.674 ± 2.411
2.674AlaPhe: 2.674 ± 2.411
9.358AlaGly: 9.358 ± 5.262
1.337AlaHis: 1.337 ± 1.208
0.0AlaIle: 0.0 ± 0.0
1.337AlaLys: 1.337 ± 1.208
6.684AlaLeu: 6.684 ± 1.429
0.0AlaMet: 0.0 ± 0.0
1.337AlaAsn: 1.337 ± 0.87
5.348AlaPro: 5.348 ± 1.627
2.674AlaGln: 2.674 ± 0.796
1.337AlaArg: 1.337 ± 0.87
9.358AlaSer: 9.358 ± 5.03
2.674AlaThr: 2.674 ± 2.411
0.0AlaVal: 0.0 ± 0.0
2.674AlaTrp: 2.674 ± 1.741
2.674AlaTyr: 2.674 ± 1.741
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
2.674CysAsp: 2.674 ± 2.411
0.0CysGlu: 0.0 ± 0.0
1.337CysPhe: 1.337 ± 0.87
2.674CysGly: 2.674 ± 2.411
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.337CysLys: 1.337 ± 1.208
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
2.674CysArg: 2.674 ± 0.796
1.337CysSer: 1.337 ± 1.208
2.674CysThr: 2.674 ± 2.411
1.337CysVal: 1.337 ± 1.208
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
5.348AspAla: 5.348 ± 1.627
2.674AspCys: 2.674 ± 2.57
2.674AspAsp: 2.674 ± 0.796
1.337AspGlu: 1.337 ± 2.639
0.0AspPhe: 0.0 ± 0.0
0.0AspGly: 0.0 ± 0.0
1.337AspHis: 1.337 ± 1.208
1.337AspIle: 1.337 ± 0.87
0.0AspLys: 0.0 ± 0.0
4.011AspLeu: 4.011 ± 1.15
0.0AspMet: 0.0 ± 0.0
1.337AspAsn: 1.337 ± 0.87
4.011AspPro: 4.011 ± 2.484
5.348AspGln: 5.348 ± 4.587
2.674AspArg: 2.674 ± 2.411
2.674AspSer: 2.674 ± 2.416
2.674AspThr: 2.674 ± 2.416
1.337AspVal: 1.337 ± 0.87
1.337AspTrp: 1.337 ± 0.87
4.011AspTyr: 4.011 ± 2.484
0.0AspXaa: 0.0 ± 0.0
Glu
2.674GluAla: 2.674 ± 2.57
0.0GluCys: 0.0 ± 0.0
4.011GluAsp: 4.011 ± 5.068
8.021GluGlu: 8.021 ± 7.711
0.0GluPhe: 0.0 ± 0.0
4.011GluGly: 4.011 ± 2.484
4.011GluHis: 4.011 ± 1.15
2.674GluIle: 2.674 ± 0.796
1.337GluLys: 1.337 ± 1.208
5.348GluLeu: 5.348 ± 2.202
1.337GluMet: 1.337 ± 0.87
0.0GluAsn: 0.0 ± 0.0
1.337GluPro: 1.337 ± 1.208
2.674GluGln: 2.674 ± 0.796
1.337GluArg: 1.337 ± 0.87
5.348GluSer: 5.348 ± 4.833
1.337GluThr: 1.337 ± 1.208
1.337GluVal: 1.337 ± 1.208
0.0GluTrp: 0.0 ± 0.0
2.674GluTyr: 2.674 ± 1.741
0.0GluXaa: 0.0 ± 0.0
Phe
2.674PheAla: 2.674 ± 0.796
1.337PheCys: 1.337 ± 2.639
2.674PheAsp: 2.674 ± 0.796
1.337PheGlu: 1.337 ± 0.87
1.337PhePhe: 1.337 ± 0.87
2.674PheGly: 2.674 ± 1.741
0.0PheHis: 0.0 ± 0.0
1.337PheIle: 1.337 ± 1.208
4.011PheLys: 4.011 ± 1.15
0.0PheLeu: 0.0 ± 0.0
0.0PheMet: 0.0 ± 0.0
0.0PheAsn: 0.0 ± 0.0
1.337PhePro: 1.337 ± 1.208
2.674PheGln: 2.674 ± 1.741
1.337PheArg: 1.337 ± 0.87
4.011PheSer: 4.011 ± 1.15
1.337PheThr: 1.337 ± 2.639
4.011PheVal: 4.011 ± 2.611
0.0PheTrp: 0.0 ± 0.0
4.011PheTyr: 4.011 ± 2.611
0.0PheXaa: 0.0 ± 0.0
Gly
8.021GlyAla: 8.021 ± 3.934
0.0GlyCys: 0.0 ± 0.0
8.021GlyAsp: 8.021 ± 4.969
6.684GlyGlu: 6.684 ± 4.494
5.348GlyPhe: 5.348 ± 3.481
9.358GlyGly: 9.358 ± 0.987
1.337GlyHis: 1.337 ± 1.208
1.337GlyIle: 1.337 ± 0.87
2.674GlyLys: 2.674 ± 1.741
5.348GlyLeu: 5.348 ± 1.592
1.337GlyMet: 1.337 ± 1.804
1.337GlyAsn: 1.337 ± 1.208
5.348GlyPro: 5.348 ± 1.627
2.674GlyGln: 2.674 ± 2.411
4.011GlyArg: 4.011 ± 1.15
8.021GlySer: 8.021 ± 0.866
6.684GlyThr: 6.684 ± 1.715
1.337GlyVal: 1.337 ± 0.87
2.674GlyTrp: 2.674 ± 1.741
2.674GlyTyr: 2.674 ± 0.796
0.0GlyXaa: 0.0 ± 0.0
His
1.337HisAla: 1.337 ± 0.87
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
1.337HisGlu: 1.337 ± 1.208
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
2.674HisIle: 2.674 ± 2.416
1.337HisLys: 1.337 ± 1.208
2.674HisLeu: 2.674 ± 2.411
1.337HisMet: 1.337 ± 2.639
0.0HisAsn: 0.0 ± 0.0
4.011HisPro: 4.011 ± 2.611
1.337HisGln: 1.337 ± 1.208
2.674HisArg: 2.674 ± 2.416
2.674HisSer: 2.674 ± 0.796
0.0HisThr: 0.0 ± 0.0
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.337HisTyr: 1.337 ± 0.87
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
1.337IleCys: 1.337 ± 0.87
2.674IleAsp: 2.674 ± 1.741
1.337IleGlu: 1.337 ± 0.87
0.0IlePhe: 0.0 ± 0.0
1.337IleGly: 1.337 ± 1.208
1.337IleHis: 1.337 ± 1.208
2.674IleIle: 2.674 ± 0.796
4.011IleLys: 4.011 ± 1.15
2.674IleLeu: 2.674 ± 2.57
1.337IleMet: 1.337 ± 1.208
2.674IleAsn: 2.674 ± 2.416
1.337IlePro: 1.337 ± 1.208
4.011IleGln: 4.011 ± 3.028
2.674IleArg: 2.674 ± 1.741
0.0IleSer: 0.0 ± 0.0
4.011IleThr: 4.011 ± 2.611
2.674IleVal: 2.674 ± 1.741
0.0IleTrp: 0.0 ± 0.0
1.337IleTyr: 1.337 ± 0.87
0.0IleXaa: 0.0 ± 0.0
Lys
1.337LysAla: 1.337 ± 1.208
0.0LysCys: 0.0 ± 0.0
2.674LysAsp: 2.674 ± 0.796
1.337LysGlu: 1.337 ± 1.208
2.674LysPhe: 2.674 ± 0.796
4.011LysGly: 4.011 ± 1.15
1.337LysHis: 1.337 ± 2.639
0.0LysIle: 0.0 ± 0.0
1.337LysLys: 1.337 ± 0.87
4.011LysLeu: 4.011 ± 2.484
2.674LysMet: 2.674 ± 1.741
1.337LysAsn: 1.337 ± 0.87
4.011LysPro: 4.011 ± 1.15
1.337LysGln: 1.337 ± 0.87
2.674LysArg: 2.674 ± 2.416
4.011LysSer: 4.011 ± 1.852
6.684LysThr: 6.684 ± 2.582
1.337LysVal: 1.337 ± 1.208
4.011LysTrp: 4.011 ± 2.611
1.337LysTyr: 1.337 ± 0.87
0.0LysXaa: 0.0 ± 0.0
Leu
6.684LeuAla: 6.684 ± 1.429
1.337LeuCys: 1.337 ± 2.639
5.348LeuAsp: 5.348 ± 2.202
2.674LeuGlu: 2.674 ± 2.416
4.011LeuPhe: 4.011 ± 1.967
8.021LeuGly: 8.021 ± 4.035
1.337LeuHis: 1.337 ± 1.208
5.348LeuIle: 5.348 ± 1.878
0.0LeuLys: 0.0 ± 0.0
1.337LeuLeu: 1.337 ± 1.208
2.674LeuMet: 2.674 ± 2.411
2.674LeuAsn: 2.674 ± 2.416
1.337LeuPro: 1.337 ± 1.208
2.674LeuGln: 2.674 ± 2.411
4.011LeuArg: 4.011 ± 1.852
4.011LeuSer: 4.011 ± 1.15
4.011LeuThr: 4.011 ± 1.15
2.674LeuVal: 2.674 ± 2.57
0.0LeuTrp: 0.0 ± 0.0
4.011LeuTyr: 4.011 ± 2.611
0.0LeuXaa: 0.0 ± 0.0
Met
4.011MetAla: 4.011 ± 4.98
1.337MetCys: 1.337 ± 0.87
0.0MetAsp: 0.0 ± 0.0
1.337MetGlu: 1.337 ± 0.87
1.337MetPhe: 1.337 ± 0.87
1.337MetGly: 1.337 ± 0.87
1.337MetHis: 1.337 ± 0.87
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
5.348MetLeu: 5.348 ± 2.202
0.0MetMet: 0.0 ± 0.0
1.337MetAsn: 1.337 ± 0.87
4.011MetPro: 4.011 ± 1.852
1.337MetGln: 1.337 ± 0.87
1.337MetArg: 1.337 ± 1.208
0.0MetSer: 0.0 ± 0.0
1.337MetThr: 1.337 ± 1.208
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.674AsnAla: 2.674 ± 1.741
1.337AsnCys: 1.337 ± 0.87
1.337AsnAsp: 1.337 ± 0.87
1.337AsnGlu: 1.337 ± 0.87
0.0AsnPhe: 0.0 ± 0.0
1.337AsnGly: 1.337 ± 1.208
0.0AsnHis: 0.0 ± 0.0
1.337AsnIle: 1.337 ± 2.639
0.0AsnLys: 0.0 ± 0.0
4.011AsnLeu: 4.011 ± 3.625
0.0AsnMet: 0.0 ± 0.0
2.674AsnAsn: 2.674 ± 0.796
5.348AsnPro: 5.348 ± 1.878
2.674AsnGln: 2.674 ± 1.741
2.674AsnArg: 2.674 ± 1.741
1.337AsnSer: 1.337 ± 0.87
1.337AsnThr: 1.337 ± 1.208
1.337AsnVal: 1.337 ± 0.87
1.337AsnTrp: 1.337 ± 1.208
1.337AsnTyr: 1.337 ± 0.87
0.0AsnXaa: 0.0 ± 0.0
Pro
2.674ProAla: 2.674 ± 1.741
0.0ProCys: 0.0 ± 0.0
1.337ProAsp: 1.337 ± 0.87
4.011ProGlu: 4.011 ± 1.852
5.348ProPhe: 5.348 ± 1.878
5.348ProGly: 5.348 ± 1.627
2.674ProHis: 2.674 ± 0.796
2.674ProIle: 2.674 ± 2.416
5.348ProLys: 5.348 ± 1.878
1.337ProLeu: 1.337 ± 1.208
2.674ProMet: 2.674 ± 1.49
4.011ProAsn: 4.011 ± 2.611
6.684ProPro: 6.684 ± 2.582
4.011ProGln: 4.011 ± 2.484
6.684ProArg: 6.684 ± 2.582
4.011ProSer: 4.011 ± 1.15
2.674ProThr: 2.674 ± 2.57
4.011ProVal: 4.011 ± 1.852
2.674ProTrp: 2.674 ± 0.796
1.337ProTyr: 1.337 ± 0.87
0.0ProXaa: 0.0 ± 0.0
Gln
6.684GlnAla: 6.684 ± 1.776
1.337GlnCys: 1.337 ± 1.208
1.337GlnAsp: 1.337 ± 2.639
2.674GlnGlu: 2.674 ± 1.741
1.337GlnPhe: 1.337 ± 1.208
4.011GlnGly: 4.011 ± 1.15
0.0GlnHis: 0.0 ± 0.0
1.337GlnIle: 1.337 ± 0.87
0.0GlnLys: 0.0 ± 0.0
4.011GlnLeu: 4.011 ± 1.967
2.674GlnMet: 2.674 ± 0.796
2.674GlnAsn: 2.674 ± 2.411
9.358GlnPro: 9.358 ± 2.99
0.0GlnGln: 0.0 ± 0.0
2.674GlnArg: 2.674 ± 2.416
4.011GlnSer: 4.011 ± 2.484
4.011GlnThr: 4.011 ± 3.028
1.337GlnVal: 1.337 ± 0.87
6.684GlnTrp: 6.684 ± 3.382
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
1.337ArgAla: 1.337 ± 0.87
1.337ArgCys: 1.337 ± 0.87
1.337ArgAsp: 1.337 ± 0.87
1.337ArgGlu: 1.337 ± 1.208
0.0ArgPhe: 0.0 ± 0.0
6.684ArgGly: 6.684 ± 4.352
0.0ArgHis: 0.0 ± 0.0
1.337ArgIle: 1.337 ± 0.87
9.358ArgLys: 9.358 ± 3.342
4.011ArgLeu: 4.011 ± 1.852
1.337ArgMet: 1.337 ± 1.208
2.674ArgAsn: 2.674 ± 1.741
4.011ArgPro: 4.011 ± 1.15
4.011ArgGln: 4.011 ± 1.852
33.422ArgArg: 33.422 ± 9.171
6.684ArgSer: 6.684 ± 1.776
5.348ArgThr: 5.348 ± 3.024
6.684ArgVal: 6.684 ± 1.776
2.674ArgTrp: 2.674 ± 2.411
2.674ArgTyr: 2.674 ± 1.741
0.0ArgXaa: 0.0 ± 0.0
Ser
4.011SerAla: 4.011 ± 1.15
1.337SerCys: 1.337 ± 1.208
1.337SerAsp: 1.337 ± 1.208
6.684SerGlu: 6.684 ± 4.801
0.0SerPhe: 0.0 ± 0.0
13.369SerGly: 13.369 ± 5.914
2.674SerHis: 2.674 ± 2.411
2.674SerIle: 2.674 ± 1.741
5.348SerLys: 5.348 ± 3.024
2.674SerLeu: 2.674 ± 2.411
1.337SerMet: 1.337 ± 1.208
4.011SerAsn: 4.011 ± 1.15
1.337SerPro: 1.337 ± 1.208
2.674SerGln: 2.674 ± 0.796
4.011SerArg: 4.011 ± 1.15
5.348SerSer: 5.348 ± 4.833
9.358SerThr: 9.358 ± 3.342
0.0SerVal: 0.0 ± 0.0
0.0SerTrp: 0.0 ± 0.0
8.021SerTyr: 8.021 ± 2.388
0.0SerXaa: 0.0 ± 0.0
Thr
2.674ThrAla: 2.674 ± 2.411
1.337ThrCys: 1.337 ± 1.208
4.011ThrAsp: 4.011 ± 3.028
4.011ThrGlu: 4.011 ± 1.852
5.348ThrPhe: 5.348 ± 1.592
6.684ThrGly: 6.684 ± 4.231
4.011ThrHis: 4.011 ± 1.15
4.011ThrIle: 4.011 ± 1.852
4.011ThrLys: 4.011 ± 2.611
1.337ThrLeu: 1.337 ± 1.208
1.337ThrMet: 1.337 ± 0.87
1.337ThrAsn: 1.337 ± 1.208
1.337ThrPro: 1.337 ± 1.208
5.348ThrGln: 5.348 ± 1.592
2.674ThrArg: 2.674 ± 0.796
9.358ThrSer: 9.358 ± 5.222
6.684ThrThr: 6.684 ± 2.582
2.674ThrVal: 2.674 ± 0.796
0.0ThrTrp: 0.0 ± 0.0
1.337ThrTyr: 1.337 ± 1.208
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
1.337ValCys: 1.337 ± 0.87
0.0ValAsp: 0.0 ± 0.0
0.0ValGlu: 0.0 ± 0.0
1.337ValPhe: 1.337 ± 0.87
0.0ValGly: 0.0 ± 0.0
0.0ValHis: 0.0 ± 0.0
2.674ValIle: 2.674 ± 2.57
2.674ValLys: 2.674 ± 2.411
5.348ValLeu: 5.348 ± 3.481
1.337ValMet: 1.337 ± 2.144
1.337ValAsn: 1.337 ± 0.87
4.011ValPro: 4.011 ± 1.15
5.348ValGln: 5.348 ± 1.878
6.684ValArg: 6.684 ± 1.776
1.337ValSer: 1.337 ± 1.208
4.011ValThr: 4.011 ± 1.852
0.0ValVal: 0.0 ± 0.0
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.337TrpAla: 1.337 ± 1.208
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
1.337TrpPhe: 1.337 ± 0.87
1.337TrpGly: 1.337 ± 0.87
0.0TrpHis: 0.0 ± 0.0
2.674TrpIle: 2.674 ± 1.741
2.674TrpLys: 2.674 ± 2.411
2.674TrpLeu: 2.674 ± 2.411
1.337TrpMet: 1.337 ± 0.87
1.337TrpAsn: 1.337 ± 0.87
1.337TrpPro: 1.337 ± 0.87
2.674TrpGln: 2.674 ± 1.741
5.348TrpArg: 5.348 ± 3.481
1.337TrpSer: 1.337 ± 0.87
0.0TrpThr: 0.0 ± 0.0
4.011TrpVal: 4.011 ± 1.15
2.674TrpTrp: 2.674 ± 1.741
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
1.337TyrAsp: 1.337 ± 0.87
1.337TyrGlu: 1.337 ± 0.87
2.674TyrPhe: 2.674 ± 1.741
2.674TyrGly: 2.674 ± 0.796
0.0TyrHis: 0.0 ± 0.0
1.337TyrIle: 1.337 ± 0.87
1.337TyrLys: 1.337 ± 0.87
1.337TyrLeu: 1.337 ± 0.87
1.337TyrMet: 1.337 ± 0.87
1.337TyrAsn: 1.337 ± 0.87
4.011TyrPro: 4.011 ± 1.15
2.674TyrGln: 2.674 ± 0.796
5.348TyrArg: 5.348 ± 3.481
1.337TyrSer: 1.337 ± 1.208
2.674TyrThr: 2.674 ± 0.796
2.674TyrVal: 2.674 ± 2.411
5.348TyrTrp: 5.348 ± 3.481
1.337TyrTyr: 1.337 ± 0.87
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (749 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski