Amino acid dipepetide frequency for Brassica cretica (Mustard)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.932AlaAla: 5.932 ± 0.043	1.152AlaCys: 1.152 ± 0.012	2.93AlaAsp: 2.93 ± 0.017	4.251AlaGlu: 4.251 ± 0.026	2.537AlaPhe: 2.537 ± 0.017	3.885AlaGly: 3.885 ± 0.027	1.241AlaHis: 1.241 ± 0.013	3.311AlaIle: 3.311 ± 0.023	3.865AlaLys: 3.865 ± 0.026	6.121AlaLeu: 6.121 ± 0.031	1.757AlaMet: 1.757 ± 0.014	2.375AlaAsn: 2.375 ± 0.014	2.825AlaPro: 2.825 ± 0.022	1.952AlaGln: 1.952 ± 0.015	3.67AlaArg: 3.67 ± 0.024	6.132AlaSer: 6.132 ± 0.028	3.779AlaThr: 3.779 ± 0.02	4.674AlaVal: 4.674 ± 0.024	0.74AlaTrp: 0.74 ± 0.01	1.662AlaTyr: 1.662 ± 0.015	0.0AlaXaa: 0.0 ± 0.0
Cys	0.885CysAla: 0.885 ± 0.009	0.532CysCys: 0.532 ± 0.008	0.905CysAsp: 0.905 ± 0.011	0.891CysGlu: 0.891 ± 0.011	0.986CysPhe: 0.986 ± 0.012	1.41CysGly: 1.41 ± 0.015	0.44CysHis: 0.44 ± 0.007	0.901CysIle: 0.901 ± 0.012	1.058CysLys: 1.058 ± 0.012	1.955CysLeu: 1.955 ± 0.015	0.413CysMet: 0.413 ± 0.007	0.756CysAsn: 0.756 ± 0.01	0.895CysPro: 0.895 ± 0.01	0.527CysGln: 0.527 ± 0.008	1.118CysArg: 1.118 ± 0.013	1.865CysSer: 1.865 ± 0.015	0.818CysThr: 0.818 ± 0.01	1.212CysVal: 1.212 ± 0.012	0.251CysTrp: 0.251 ± 0.006	0.569CysTyr: 0.569 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	3.256AspAla: 3.256 ± 0.021	0.928AspCys: 0.928 ± 0.01	3.755AspAsp: 3.755 ± 0.028	4.317AspGlu: 4.317 ± 0.025	2.304AspPhe: 2.304 ± 0.017	3.757AspGly: 3.757 ± 0.021	1.359AspHis: 1.359 ± 0.014	2.811AspIle: 2.811 ± 0.02	2.718AspLys: 2.718 ± 0.019	5.214AspLeu: 5.214 ± 0.026	1.377AspMet: 1.377 ± 0.013	1.986AspAsn: 1.986 ± 0.017	2.768AspPro: 2.768 ± 0.019	1.825AspGln: 1.825 ± 0.014	2.737AspArg: 2.737 ± 0.022	4.343AspSer: 4.343 ± 0.024	2.432AspThr: 2.432 ± 0.017	3.785AspVal: 3.785 ± 0.023	0.675AspTrp: 0.675 ± 0.008	1.466AspTyr: 1.466 ± 0.014	0.0AspXaa: 0.0 ± 0.0
Glu	5.117GluAla: 5.117 ± 0.028	0.883GluCys: 0.883 ± 0.01	4.257GluAsp: 4.257 ± 0.029	7.192GluGlu: 7.192 ± 0.052	2.391GluPhe: 2.391 ± 0.015	3.67GluGly: 3.67 ± 0.023	1.29GluHis: 1.29 ± 0.013	3.822GluIle: 3.822 ± 0.024	5.009GluLys: 5.009 ± 0.036	5.862GluLeu: 5.862 ± 0.031	1.913GluMet: 1.913 ± 0.015	2.952GluAsn: 2.952 ± 0.021	2.4GluPro: 2.4 ± 0.019	2.079GluGln: 2.079 ± 0.017	3.777GluArg: 3.777 ± 0.027	4.891GluSer: 4.891 ± 0.03	3.859GluThr: 3.859 ± 0.025	4.367GluVal: 4.367 ± 0.026	0.729GluTrp: 0.729 ± 0.01	1.586GluTyr: 1.586 ± 0.013	0.0GluXaa: 0.0 ± 0.0
Phe	2.383PheAla: 2.383 ± 0.02	0.87PheCys: 0.87 ± 0.01	2.306PheAsp: 2.306 ± 0.015	2.276PheGlu: 2.276 ± 0.019	1.962PhePhe: 1.962 ± 0.015	2.927PheGly: 2.927 ± 0.022	1.113PheHis: 1.113 ± 0.012	1.919PheIle: 1.919 ± 0.018	2.072PheLys: 2.072 ± 0.015	4.243PheLeu: 4.243 ± 0.023	0.974PheMet: 0.974 ± 0.011	1.568PheAsn: 1.568 ± 0.015	2.081PhePro: 2.081 ± 0.017	1.46PheGln: 1.46 ± 0.014	2.222PheArg: 2.222 ± 0.018	4.065PheSer: 4.065 ± 0.025	2.165PheThr: 2.165 ± 0.018	2.773PheVal: 2.773 ± 0.018	0.589PheTrp: 0.589 ± 0.008	1.194PheTyr: 1.194 ± 0.013	0.0PheXaa: 0.0 ± 0.0
Gly	3.586GlyAla: 3.586 ± 0.026	1.27GlyCys: 1.27 ± 0.012	3.572GlyAsp: 3.572 ± 0.021	4.052GlyGlu: 4.052 ± 0.025	3.111GlyPhe: 3.111 ± 0.022	5.554GlyGly: 5.554 ± 0.043	1.454GlyHis: 1.454 ± 0.013	3.125GlyIle: 3.125 ± 0.021	3.925GlyLys: 3.925 ± 0.023	5.638GlyLeu: 5.638 ± 0.027	1.456GlyMet: 1.456 ± 0.014	2.829GlyAsn: 2.829 ± 0.022	2.334GlyPro: 2.334 ± 0.019	1.913GlyGln: 1.913 ± 0.015	3.83GlyArg: 3.83 ± 0.021	6.051GlySer: 6.051 ± 0.035	3.206GlyThr: 3.206 ± 0.021	4.309GlyVal: 4.309 ± 0.025	0.829GlyTrp: 0.829 ± 0.01	1.972GlyTyr: 1.972 ± 0.017	0.0GlyXaa: 0.0 ± 0.0
His	1.31HisAla: 1.31 ± 0.013	0.491HisCys: 0.491 ± 0.008	1.127HisAsp: 1.127 ± 0.013	1.318HisGlu: 1.318 ± 0.014	0.917HisPhe: 0.917 ± 0.011	1.665HisGly: 1.665 ± 0.015	1.01HisHis: 1.01 ± 0.015	1.133HisIle: 1.133 ± 0.013	1.144HisLys: 1.144 ± 0.012	2.389HisLeu: 2.389 ± 0.018	0.571HisMet: 0.571 ± 0.008	0.897HisAsn: 0.897 ± 0.011	1.349HisPro: 1.349 ± 0.013	1.087HisGln: 1.087 ± 0.012	1.552HisArg: 1.552 ± 0.015	1.903HisSer: 1.903 ± 0.016	1.013HisThr: 1.013 ± 0.01	1.623HisVal: 1.623 ± 0.015	0.31HisTrp: 0.31 ± 0.006	0.647HisTyr: 0.647 ± 0.008	0.0HisXaa: 0.0 ± 0.0
Ile	3.282IleAla: 3.282 ± 0.019	1.042IleCys: 1.042 ± 0.012	3.157IleAsp: 3.157 ± 0.024	3.008IleGlu: 3.008 ± 0.021	2.047IlePhe: 2.047 ± 0.018	3.102IleGly: 3.102 ± 0.018	1.246IleHis: 1.246 ± 0.013	2.409IleIle: 2.409 ± 0.018	2.71IleLys: 2.71 ± 0.017	4.688IleLeu: 4.688 ± 0.021	1.083IleMet: 1.083 ± 0.01	2.066IleAsn: 2.066 ± 0.016	2.788IlePro: 2.788 ± 0.022	1.822IleGln: 1.822 ± 0.015	2.704IleArg: 2.704 ± 0.017	4.65IleSer: 4.65 ± 0.023	2.604IleThr: 2.604 ± 0.02	3.218IleVal: 3.218 ± 0.021	0.664IleTrp: 0.664 ± 0.008	1.398IleTyr: 1.398 ± 0.013	0.0IleXaa: 0.0 ± 0.0
Lys	4.0LysAla: 4.0 ± 0.026	0.892LysCys: 0.892 ± 0.01	3.18LysAsp: 3.18 ± 0.019	4.815LysGlu: 4.815 ± 0.032	1.989LysPhe: 1.989 ± 0.017	3.397LysGly: 3.397 ± 0.023	1.303LysHis: 1.303 ± 0.011	3.083LysIle: 3.083 ± 0.019	5.079LysLys: 5.079 ± 0.04	5.822LysLeu: 5.822 ± 0.027	1.544LysMet: 1.544 ± 0.016	2.478LysAsn: 2.478 ± 0.02	2.895LysPro: 2.895 ± 0.018	2.166LysGln: 2.166 ± 0.016	3.93LysArg: 3.93 ± 0.026	4.632LysSer: 4.632 ± 0.028	3.272LysThr: 3.272 ± 0.02	3.649LysVal: 3.649 ± 0.021	0.754LysTrp: 0.754 ± 0.01	1.42LysTyr: 1.42 ± 0.012	0.0LysXaa: 0.0 ± 0.0
Leu	6.158LeuAla: 6.158 ± 0.032	1.888LeuCys: 1.888 ± 0.015	4.973LeuAsp: 4.973 ± 0.025	6.33LeuGlu: 6.33 ± 0.033	3.773LeuPhe: 3.773 ± 0.022	5.631LeuGly: 5.631 ± 0.03	2.428LeuHis: 2.428 ± 0.019	4.428LeuIle: 4.428 ± 0.024	5.809LeuLys: 5.809 ± 0.027	9.529LeuLeu: 9.529 ± 0.044	2.281LeuMet: 2.281 ± 0.016	3.631LeuAsn: 3.631 ± 0.02	5.074LeuPro: 5.074 ± 0.028	3.831LeuGln: 3.831 ± 0.027	5.773LeuArg: 5.773 ± 0.026	8.636LeuSer: 8.636 ± 0.045	4.674LeuThr: 4.674 ± 0.025	6.575LeuVal: 6.575 ± 0.031	1.186LeuTrp: 1.186 ± 0.012	2.283LeuTyr: 2.283 ± 0.017	0.0LeuXaa: 0.0 ± 0.0
Met	1.982MetAla: 1.982 ± 0.017	0.361MetCys: 0.361 ± 0.006	1.445MetAsp: 1.445 ± 0.012	2.044MetGlu: 2.044 ± 0.016	0.986MetPhe: 0.986 ± 0.01	1.526MetGly: 1.526 ± 0.014	0.493MetHis: 0.493 ± 0.007	1.293MetIle: 1.293 ± 0.011	1.707MetLys: 1.707 ± 0.015	2.094MetLeu: 2.094 ± 0.016	0.795MetMet: 0.795 ± 0.01	1.03MetAsn: 1.03 ± 0.011	0.96MetPro: 0.96 ± 0.011	0.845MetGln: 0.845 ± 0.01	1.363MetArg: 1.363 ± 0.013	2.038MetSer: 2.038 ± 0.015	1.149MetThr: 1.149 ± 0.011	1.761MetVal: 1.761 ± 0.013	0.286MetTrp: 0.286 ± 0.005	0.597MetTyr: 0.597 ± 0.009	0.0MetXaa: 0.0 ± 0.0
Asn	2.471AsnAla: 2.471 ± 0.017	0.716AsnCys: 0.716 ± 0.01	1.935AsnAsp: 1.935 ± 0.015	2.397AsnGlu: 2.397 ± 0.018	1.587AsnPhe: 1.587 ± 0.015	2.962AsnGly: 2.962 ± 0.02	1.103AsnHis: 1.103 ± 0.012	2.149AsnIle: 2.149 ± 0.016	2.343AsnLys: 2.343 ± 0.016	4.187AsnLeu: 4.187 ± 0.026	1.075AsnMet: 1.075 ± 0.011	2.217AsnAsn: 2.217 ± 0.023	2.371AsnPro: 2.371 ± 0.018	1.718AsnGln: 1.718 ± 0.014	2.195AsnArg: 2.195 ± 0.016	3.402AsnSer: 3.402 ± 0.023	2.033AsnThr: 2.033 ± 0.017	2.649AsnVal: 2.649 ± 0.019	0.514AsnTrp: 0.514 ± 0.007	1.091AsnTyr: 1.091 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	2.946ProAla: 2.946 ± 0.022	0.812ProCys: 0.812 ± 0.01	2.512ProAsp: 2.512 ± 0.018	3.441ProGlu: 3.441 ± 0.023	1.946ProPhe: 1.946 ± 0.018	2.769ProGly: 2.769 ± 0.021	1.127ProHis: 1.127 ± 0.012	2.187ProIle: 2.187 ± 0.014	2.724ProLys: 2.724 ± 0.019	4.392ProLeu: 4.392 ± 0.022	1.07ProMet: 1.07 ± 0.012	2.07ProAsn: 2.07 ± 0.019	4.217ProPro: 4.217 ± 0.056	1.777ProGln: 1.777 ± 0.017	2.863ProArg: 2.863 ± 0.021	5.5ProSer: 5.5 ± 0.031	2.734ProThr: 2.734 ± 0.018	3.276ProVal: 3.276 ± 0.02	0.629ProTrp: 0.629 ± 0.007	1.263ProTyr: 1.263 ± 0.014	0.0ProXaa: 0.0 ± 0.0
Gln	2.259GlnAla: 2.259 ± 0.019	0.534GlnCys: 0.534 ± 0.008	1.677GlnAsp: 1.677 ± 0.012	2.491GlnGlu: 2.491 ± 0.02	1.239GlnPhe: 1.239 ± 0.013	2.082GlnGly: 2.082 ± 0.017	0.884GlnHis: 0.884 ± 0.012	1.823GlnIle: 1.823 ± 0.014	2.071GlnLys: 2.071 ± 0.017	3.159GlnLeu: 3.159 ± 0.022	0.952GlnMet: 0.952 ± 0.01	1.562GlnAsn: 1.562 ± 0.015	1.765GlnPro: 1.765 ± 0.018	1.888GlnGln: 1.888 ± 0.023	2.289GlnArg: 2.289 ± 0.02	2.805GlnSer: 2.805 ± 0.02	1.986GlnThr: 1.986 ± 0.016	2.289GlnVal: 2.289 ± 0.016	0.439GlnTrp: 0.439 ± 0.009	0.82GlnTyr: 0.82 ± 0.01	0.0GlnXaa: 0.0 ± 0.0
Arg	3.456ArgAla: 3.456 ± 0.021	1.145ArgCys: 1.145 ± 0.013	2.972ArgAsp: 2.972 ± 0.021	3.812ArgGlu: 3.812 ± 0.026	2.575ArgPhe: 2.575 ± 0.016	3.6ArgGly: 3.6 ± 0.021	1.391ArgHis: 1.391 ± 0.012	2.907ArgIle: 2.907 ± 0.017	3.852ArgLys: 3.852 ± 0.025	5.49ArgLeu: 5.49 ± 0.026	1.371ArgMet: 1.371 ± 0.012	2.557ArgAsn: 2.557 ± 0.019	2.672ArgPro: 2.672 ± 0.021	1.981ArgGln: 1.981 ± 0.014	4.942ArgArg: 4.942 ± 0.03	5.443ArgSer: 5.443 ± 0.03	2.785ArgThr: 2.785 ± 0.018	3.795ArgVal: 3.795 ± 0.024	0.817ArgTrp: 0.817 ± 0.009	1.519ArgTyr: 1.519 ± 0.013	0.0ArgXaa: 0.0 ± 0.0
Ser	5.166SerAla: 5.166 ± 0.026	1.781SerCys: 1.781 ± 0.013	4.672SerAsp: 4.672 ± 0.024	5.113SerGlu: 5.113 ± 0.031	4.173SerPhe: 4.173 ± 0.027	6.058SerGly: 6.058 ± 0.035	2.054SerHis: 2.054 ± 0.016	4.479SerIle: 4.479 ± 0.028	4.867SerLys: 4.867 ± 0.028	9.198SerLeu: 9.198 ± 0.043	2.089SerMet: 2.089 ± 0.017	3.676SerAsn: 3.676 ± 0.023	4.997SerPro: 4.997 ± 0.043	3.058SerGln: 3.058 ± 0.021	5.203SerArg: 5.203 ± 0.031	11.965SerSer: 11.965 ± 0.06	4.835SerThr: 4.835 ± 0.031	5.711SerVal: 5.711 ± 0.025	1.274SerTrp: 1.274 ± 0.012	2.366SerTyr: 2.366 ± 0.017	0.0SerXaa: 0.0 ± 0.0
Thr	3.469ThrAla: 3.469 ± 0.019	1.036ThrCys: 1.036 ± 0.011	2.483ThrAsp: 2.483 ± 0.019	3.257ThrGlu: 3.257 ± 0.021	2.004ThrPhe: 2.004 ± 0.014	3.368ThrGly: 3.368 ± 0.021	1.139ThrHis: 1.139 ± 0.012	2.602ThrIle: 2.602 ± 0.019	2.993ThrLys: 2.993 ± 0.02	4.753ThrLeu: 4.753 ± 0.022	1.288ThrMet: 1.288 ± 0.013	2.102ThrAsn: 2.102 ± 0.013	2.862ThrPro: 2.862 ± 0.023	1.689ThrGln: 1.689 ± 0.014	3.018ThrArg: 3.018 ± 0.019	5.098ThrSer: 5.098 ± 0.028	3.431ThrThr: 3.431 ± 0.022	3.605ThrVal: 3.605 ± 0.019	0.697ThrTrp: 0.697 ± 0.008	1.354ThrTyr: 1.354 ± 0.011	0.0ThrXaa: 0.0 ± 0.0
Val	4.804ValAla: 4.804 ± 0.022	1.22ValCys: 1.22 ± 0.013	3.825ValAsp: 3.825 ± 0.022	4.65ValGlu: 4.65 ± 0.025	2.818ValPhe: 2.818 ± 0.021	3.937ValGly: 3.937 ± 0.023	1.475ValHis: 1.475 ± 0.013	3.261ValIle: 3.261 ± 0.023	4.012ValLys: 4.012 ± 0.022	6.34ValLeu: 6.34 ± 0.03	1.698ValMet: 1.698 ± 0.013	2.511ValAsn: 2.511 ± 0.016	3.301ValPro: 3.301 ± 0.021	2.133ValGln: 2.133 ± 0.016	3.435ValArg: 3.435 ± 0.018	6.096ValSer: 6.096 ± 0.029	3.502ValThr: 3.502 ± 0.021	5.192ValVal: 5.192 ± 0.028	0.848ValTrp: 0.848 ± 0.01	1.935ValTyr: 1.935 ± 0.014	0.0ValXaa: 0.0 ± 0.0
Trp	0.694TrpAla: 0.694 ± 0.009	0.273TrpCys: 0.273 ± 0.006	0.668TrpAsp: 0.668 ± 0.008	0.808TrpGlu: 0.808 ± 0.011	0.586TrpPhe: 0.586 ± 0.008	0.704TrpGly: 0.704 ± 0.01	0.235TrpHis: 0.235 ± 0.005	0.722TrpIle: 0.722 ± 0.009	0.892TrpLys: 0.892 ± 0.01	1.258TrpLeu: 1.258 ± 0.013	0.341TrpMet: 0.341 ± 0.007	0.684TrpAsn: 0.684 ± 0.01	0.501TrpPro: 0.501 ± 0.007	0.378TrpGln: 0.378 ± 0.006	0.971TrpArg: 0.971 ± 0.011	1.088TrpSer: 1.088 ± 0.011	0.688TrpThr: 0.688 ± 0.01	0.778TrpVal: 0.778 ± 0.009	0.243TrpTrp: 0.243 ± 0.006	0.342TrpTyr: 0.342 ± 0.007	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.634TyrAla: 1.634 ± 0.015	0.558TyrCys: 0.558 ± 0.008	1.46TyrAsp: 1.46 ± 0.014	1.584TyrGlu: 1.584 ± 0.015	1.23TyrPhe: 1.23 ± 0.014	2.013TyrGly: 2.013 ± 0.017	0.676TyrHis: 0.676 ± 0.01	1.321TyrIle: 1.321 ± 0.013	1.447TyrLys: 1.447 ± 0.014	2.558TyrLeu: 2.558 ± 0.02	0.709TyrMet: 0.709 ± 0.009	1.166TyrAsn: 1.166 ± 0.012	1.198TyrPro: 1.198 ± 0.013	0.888TyrGln: 0.888 ± 0.011	1.491TyrArg: 1.491 ± 0.014	2.134TyrSer: 2.134 ± 0.017	1.282TyrThr: 1.282 ± 0.014	1.751TyrVal: 1.751 ± 0.014	0.382TyrTrp: 0.382 ± 0.007	0.921TyrTyr: 0.921 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 30345 proteins (9102698 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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