Amino acid dipepetide frequency for Pseudodesulfovibrio piezophilus (strain DSM 21447 / JCM 15486 / C1TLV30) (Desulfovibrio piezophilus)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.11AlaAla: 8.11 ± 0.131	1.246AlaCys: 1.246 ± 0.038	4.653AlaAsp: 4.653 ± 0.074	5.833AlaGlu: 5.833 ± 0.081	3.422AlaPhe: 3.422 ± 0.062	6.998AlaGly: 6.998 ± 0.091	1.837AlaHis: 1.837 ± 0.047	4.927AlaIle: 4.927 ± 0.077	4.294AlaLys: 4.294 ± 0.071	9.641AlaLeu: 9.641 ± 0.097	2.982AlaMet: 2.982 ± 0.054	2.417AlaAsn: 2.417 ± 0.047	3.086AlaPro: 3.086 ± 0.068	3.161AlaGln: 3.161 ± 0.058	4.708AlaArg: 4.708 ± 0.069	4.945AlaSer: 4.945 ± 0.07	4.293AlaThr: 4.293 ± 0.065	6.222AlaVal: 6.222 ± 0.086	1.037AlaTrp: 1.037 ± 0.034	2.299AlaTyr: 2.299 ± 0.045	0.0AlaXaa: 0.0 ± 0.0
Cys	1.083CysAla: 1.083 ± 0.032	0.231CysCys: 0.231 ± 0.015	0.674CysAsp: 0.674 ± 0.029	0.74CysGlu: 0.74 ± 0.027	0.542CysPhe: 0.542 ± 0.021	1.309CysGly: 1.309 ± 0.039	0.455CysHis: 0.455 ± 0.029	0.728CysIle: 0.728 ± 0.025	0.504CysLys: 0.504 ± 0.023	1.329CysLeu: 1.329 ± 0.04	0.343CysMet: 0.343 ± 0.018	0.391CysAsn: 0.391 ± 0.02	0.813CysPro: 0.813 ± 0.034	0.377CysGln: 0.377 ± 0.021	0.779CysArg: 0.779 ± 0.028	0.845CysSer: 0.845 ± 0.031	0.678CysThr: 0.678 ± 0.025	0.851CysVal: 0.851 ± 0.031	0.141CysTrp: 0.141 ± 0.012	0.341CysTyr: 0.341 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	4.545AspAla: 4.545 ± 0.072	0.693AspCys: 0.693 ± 0.028	3.031AspAsp: 3.031 ± 0.066	3.934AspGlu: 3.934 ± 0.063	2.8AspPhe: 2.8 ± 0.056	4.146AspGly: 4.146 ± 0.097	1.167AspHis: 1.167 ± 0.035	4.268AspIle: 4.268 ± 0.066	2.853AspLys: 2.853 ± 0.055	5.59AspLeu: 5.59 ± 0.07	1.788AspMet: 1.788 ± 0.039	1.691AspAsn: 1.691 ± 0.044	2.598AspPro: 2.598 ± 0.049	1.737AspGln: 1.737 ± 0.042	2.944AspArg: 2.944 ± 0.062	3.062AspSer: 3.062 ± 0.054	2.777AspThr: 2.777 ± 0.053	3.952AspVal: 3.952 ± 0.06	0.759AspTrp: 0.759 ± 0.026	1.722AspTyr: 1.722 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	6.101GluAla: 6.101 ± 0.08	0.731GluCys: 0.731 ± 0.029	3.459GluAsp: 3.459 ± 0.068	5.026GluGlu: 5.026 ± 0.085	2.52GluPhe: 2.52 ± 0.045	4.377GluGly: 4.377 ± 0.063	1.437GluHis: 1.437 ± 0.041	4.432GluIle: 4.432 ± 0.071	4.386GluLys: 4.386 ± 0.067	6.632GluLeu: 6.632 ± 0.087	2.121GluMet: 2.121 ± 0.044	2.737GluAsn: 2.737 ± 0.047	2.134GluPro: 2.134 ± 0.05	2.49GluGln: 2.49 ± 0.05	3.91GluArg: 3.91 ± 0.072	3.79GluSer: 3.79 ± 0.062	3.82GluThr: 3.82 ± 0.064	4.442GluVal: 4.442 ± 0.072	0.644GluTrp: 0.644 ± 0.024	1.91GluTyr: 1.91 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	3.25PheAla: 3.25 ± 0.055	0.666PheCys: 0.666 ± 0.027	2.589PheAsp: 2.589 ± 0.052	2.511PheGlu: 2.511 ± 0.053	2.124PhePhe: 2.124 ± 0.053	3.3PheGly: 3.3 ± 0.058	0.968PheHis: 0.968 ± 0.029	2.647PheIle: 2.647 ± 0.054	2.03PheLys: 2.03 ± 0.045	4.427PheLeu: 4.427 ± 0.073	1.336PheMet: 1.336 ± 0.037	1.464PheAsn: 1.464 ± 0.032	1.87PhePro: 1.87 ± 0.042	1.2PheGln: 1.2 ± 0.033	2.144PheArg: 2.144 ± 0.048	3.099PheSer: 3.099 ± 0.053	2.328PheThr: 2.328 ± 0.048	2.802PheVal: 2.802 ± 0.055	0.576PheTrp: 0.576 ± 0.026	1.254PheTyr: 1.254 ± 0.039	0.0PheXaa: 0.0 ± 0.0
Gly	6.033GlyAla: 6.033 ± 0.083	1.236GlyCys: 1.236 ± 0.04	4.001GlyAsp: 4.001 ± 0.066	4.859GlyGlu: 4.859 ± 0.067	3.563GlyPhe: 3.563 ± 0.056	5.826GlyGly: 5.826 ± 0.097	1.814GlyHis: 1.814 ± 0.047	5.18GlyIle: 5.18 ± 0.067	4.658GlyLys: 4.658 ± 0.074	8.105GlyLeu: 8.105 ± 0.094	2.628GlyMet: 2.628 ± 0.058	2.46GlyAsn: 2.46 ± 0.051	2.455GlyPro: 2.455 ± 0.047	2.591GlyGln: 2.591 ± 0.051	4.047GlyArg: 4.047 ± 0.076	4.287GlySer: 4.287 ± 0.068	4.405GlyThr: 4.405 ± 0.074	5.899GlyVal: 5.899 ± 0.077	1.029GlyTrp: 1.029 ± 0.032	2.425GlyTyr: 2.425 ± 0.056	0.0GlyXaa: 0.0 ± 0.0
His	1.763HisAla: 1.763 ± 0.044	0.353HisCys: 0.353 ± 0.021	1.36HisAsp: 1.36 ± 0.037	1.403HisGlu: 1.403 ± 0.039	1.043HisPhe: 1.043 ± 0.033	1.869HisGly: 1.869 ± 0.048	0.612HisHis: 0.612 ± 0.022	1.363HisIle: 1.363 ± 0.036	0.954HisLys: 0.954 ± 0.03	2.19HisLeu: 2.19 ± 0.047	0.592HisMet: 0.592 ± 0.023	0.694HisAsn: 0.694 ± 0.025	1.287HisPro: 1.287 ± 0.034	0.698HisGln: 0.698 ± 0.025	1.129HisArg: 1.129 ± 0.034	1.296HisSer: 1.296 ± 0.035	1.148HisThr: 1.148 ± 0.037	1.366HisVal: 1.366 ± 0.036	0.281HisTrp: 0.281 ± 0.015	0.693HisTyr: 0.693 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	5.292IleAla: 5.292 ± 0.089	0.838IleCys: 0.838 ± 0.028	3.367IleAsp: 3.367 ± 0.063	3.898IleGlu: 3.898 ± 0.071	2.53IlePhe: 2.53 ± 0.053	4.714IleGly: 4.714 ± 0.07	1.356IleHis: 1.356 ± 0.039	3.668IleIle: 3.668 ± 0.072	3.087IleLys: 3.087 ± 0.058	6.46IleLeu: 6.46 ± 0.079	1.76IleMet: 1.76 ± 0.046	2.257IleAsn: 2.257 ± 0.052	3.211IlePro: 3.211 ± 0.054	1.93IleGln: 1.93 ± 0.042	3.503IleArg: 3.503 ± 0.064	3.93IleSer: 3.93 ± 0.065	3.335IleThr: 3.335 ± 0.065	4.179IleVal: 4.179 ± 0.067	0.633IleTrp: 0.633 ± 0.027	1.602IleTyr: 1.602 ± 0.04	0.0IleXaa: 0.0 ± 0.0
Lys	4.885LysAla: 4.885 ± 0.072	0.493LysCys: 0.493 ± 0.023	2.964LysAsp: 2.964 ± 0.062	3.749LysGlu: 3.749 ± 0.076	1.541LysPhe: 1.541 ± 0.04	3.979LysGly: 3.979 ± 0.063	1.062LysHis: 1.062 ± 0.032	3.17LysIle: 3.17 ± 0.054	3.681LysLys: 3.681 ± 0.089	4.651LysLeu: 4.651 ± 0.072	1.528LysMet: 1.528 ± 0.038	2.107LysAsn: 2.107 ± 0.044	2.18LysPro: 2.18 ± 0.044	1.909LysGln: 1.909 ± 0.044	3.118LysArg: 3.118 ± 0.06	2.978LysSer: 2.978 ± 0.051	3.108LysThr: 3.108 ± 0.054	3.468LysVal: 3.468 ± 0.061	0.524LysTrp: 0.524 ± 0.02	1.478LysTyr: 1.478 ± 0.042	0.0LysXaa: 0.0 ± 0.0
Leu	9.686LeuAla: 9.686 ± 0.112	1.329LeuCys: 1.329 ± 0.037	6.179LeuAsp: 6.179 ± 0.079	6.834LeuGlu: 6.834 ± 0.079	4.559LeuPhe: 4.559 ± 0.077	8.183LeuGly: 8.183 ± 0.094	2.144LeuHis: 2.144 ± 0.048	5.652LeuIle: 5.652 ± 0.093	5.544LeuLys: 5.544 ± 0.079	9.724LeuLeu: 9.724 ± 0.121	2.729LeuMet: 2.729 ± 0.055	3.541LeuAsn: 3.541 ± 0.06	4.918LeuPro: 4.918 ± 0.075	2.933LeuGln: 2.933 ± 0.054	5.182LeuArg: 5.182 ± 0.069	6.798LeuSer: 6.798 ± 0.083	5.851LeuThr: 5.851 ± 0.084	6.826LeuVal: 6.826 ± 0.081	1.054LeuTrp: 1.054 ± 0.037	2.447LeuTyr: 2.447 ± 0.053	0.0LeuXaa: 0.0 ± 0.0
Met	3.123MetAla: 3.123 ± 0.065	0.305MetCys: 0.305 ± 0.019	1.868MetAsp: 1.868 ± 0.043	2.01MetGlu: 2.01 ± 0.044	0.983MetPhe: 0.983 ± 0.031	2.341MetGly: 2.341 ± 0.049	0.645MetHis: 0.645 ± 0.027	1.59MetIle: 1.59 ± 0.04	1.671MetLys: 1.671 ± 0.039	2.752MetLeu: 2.752 ± 0.054	0.683MetMet: 0.683 ± 0.028	1.167MetAsn: 1.167 ± 0.033	1.428MetPro: 1.428 ± 0.04	1.068MetGln: 1.068 ± 0.03	1.59MetArg: 1.59 ± 0.034	1.88MetSer: 1.88 ± 0.038	1.936MetThr: 1.936 ± 0.046	2.093MetVal: 2.093 ± 0.04	0.216MetTrp: 0.216 ± 0.015	0.573MetTyr: 0.573 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	2.811AsnAla: 2.811 ± 0.062	0.453AsnCys: 0.453 ± 0.021	1.795AsnAsp: 1.795 ± 0.053	2.121AsnGlu: 2.121 ± 0.043	1.364AsnPhe: 1.364 ± 0.04	2.57AsnGly: 2.57 ± 0.051	0.687AsnHis: 0.687 ± 0.026	2.27AsnIle: 2.27 ± 0.044	1.618AsnLys: 1.618 ± 0.041	3.457AsnLeu: 3.457 ± 0.064	1.033AsnMet: 1.033 ± 0.03	1.13AsnAsn: 1.13 ± 0.033	1.999AsnPro: 1.999 ± 0.041	1.057AsnGln: 1.057 ± 0.033	1.967AsnArg: 1.967 ± 0.043	1.882AsnSer: 1.882 ± 0.045	1.806AsnThr: 1.806 ± 0.043	2.305AsnVal: 2.305 ± 0.049	0.508AsnTrp: 0.508 ± 0.023	0.932AsnTyr: 0.932 ± 0.031	0.0AsnXaa: 0.0 ± 0.0
Pro	3.408ProAla: 3.408 ± 0.064	0.512ProCys: 0.512 ± 0.025	3.015ProAsp: 3.015 ± 0.059	3.833ProGlu: 3.833 ± 0.068	1.979ProPhe: 1.979 ± 0.043	3.592ProGly: 3.592 ± 0.061	1.019ProHis: 1.019 ± 0.033	2.293ProIle: 2.293 ± 0.043	2.091ProLys: 2.091 ± 0.052	4.362ProLeu: 4.362 ± 0.062	1.244ProMet: 1.244 ± 0.037	1.31ProAsn: 1.31 ± 0.034	1.81ProPro: 1.81 ± 0.051	1.455ProGln: 1.455 ± 0.038	1.913ProArg: 1.913 ± 0.044	2.595ProSer: 2.595 ± 0.045	2.135ProThr: 2.135 ± 0.047	3.569ProVal: 3.569 ± 0.051	0.554ProTrp: 0.554 ± 0.022	1.231ProTyr: 1.231 ± 0.036	0.0ProXaa: 0.0 ± 0.0
Gln	3.488GlnAla: 3.488 ± 0.057	0.443GlnCys: 0.443 ± 0.021	1.721GlnAsp: 1.721 ± 0.042	2.299GlnGlu: 2.299 ± 0.058	1.367GlnPhe: 1.367 ± 0.04	2.547GlnGly: 2.547 ± 0.05	0.679GlnHis: 0.679 ± 0.028	1.985GlnIle: 1.985 ± 0.043	1.825GlnLys: 1.825 ± 0.046	3.051GlnLeu: 3.051 ± 0.059	0.945GlnMet: 0.945 ± 0.026	1.181GlnAsn: 1.181 ± 0.035	1.209GlnPro: 1.209 ± 0.036	1.299GlnGln: 1.299 ± 0.037	1.856GlnArg: 1.856 ± 0.043	2.077GlnSer: 2.077 ± 0.045	1.92GlnThr: 1.92 ± 0.042	2.304GlnVal: 2.304 ± 0.05	0.42GlnTrp: 0.42 ± 0.021	0.908GlnTyr: 0.908 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	4.067ArgAla: 4.067 ± 0.062	0.647ArgCys: 0.647 ± 0.025	2.945ArgAsp: 2.945 ± 0.053	4.06ArgGlu: 4.06 ± 0.07	2.532ArgPhe: 2.532 ± 0.048	3.302ArgGly: 3.302 ± 0.061	1.305ArgHis: 1.305 ± 0.032	3.622ArgIle: 3.622 ± 0.055	3.182ArgLys: 3.182 ± 0.054	5.901ArgLeu: 5.901 ± 0.087	1.655ArgMet: 1.655 ± 0.041	1.899ArgAsn: 1.899 ± 0.04	2.249ArgPro: 2.249 ± 0.05	2.219ArgGln: 2.219 ± 0.05	3.087ArgArg: 3.087 ± 0.063	3.053ArgSer: 3.053 ± 0.05	2.794ArgThr: 2.794 ± 0.052	3.453ArgVal: 3.453 ± 0.053	0.591ArgTrp: 0.591 ± 0.023	1.587ArgTyr: 1.587 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	4.608SerAla: 4.608 ± 0.076	0.725SerCys: 0.725 ± 0.029	3.111SerAsp: 3.111 ± 0.058	3.672SerGlu: 3.672 ± 0.065	2.703SerPhe: 2.703 ± 0.052	5.469SerGly: 5.469 ± 0.086	1.359SerHis: 1.359 ± 0.037	3.85SerIle: 3.85 ± 0.064	2.739SerLys: 2.739 ± 0.057	6.763SerLeu: 6.763 ± 0.094	1.924SerMet: 1.924 ± 0.042	1.783SerAsn: 1.783 ± 0.043	2.705SerPro: 2.705 ± 0.051	2.169SerGln: 2.169 ± 0.047	3.342SerArg: 3.342 ± 0.056	3.839SerSer: 3.839 ± 0.079	3.135SerThr: 3.135 ± 0.06	4.315SerVal: 4.315 ± 0.075	0.703SerTrp: 0.703 ± 0.027	1.522SerTyr: 1.522 ± 0.039	0.0SerXaa: 0.0 ± 0.0
Thr	4.627ThrAla: 4.627 ± 0.079	0.719ThrCys: 0.719 ± 0.028	2.946ThrAsp: 2.946 ± 0.074	3.123ThrGlu: 3.123 ± 0.062	2.169ThrPhe: 2.169 ± 0.047	4.798ThrGly: 4.798 ± 0.068	1.21ThrHis: 1.21 ± 0.042	3.433ThrIle: 3.433 ± 0.053	2.236ThrLys: 2.236 ± 0.047	6.054ThrLeu: 6.054 ± 0.08	1.635ThrMet: 1.635 ± 0.038	1.685ThrAsn: 1.685 ± 0.046	3.129ThrPro: 3.129 ± 0.057	1.689ThrGln: 1.689 ± 0.042	2.764ThrArg: 2.764 ± 0.054	3.179ThrSer: 3.179 ± 0.065	2.991ThrThr: 2.991 ± 0.07	4.214ThrVal: 4.214 ± 0.079	0.55ThrTrp: 0.55 ± 0.021	1.446ThrTyr: 1.446 ± 0.04	0.0ThrXaa: 0.0 ± 0.0
Val	6.154ValAla: 6.154 ± 0.094	0.996ValCys: 0.996 ± 0.029	4.094ValAsp: 4.094 ± 0.063	4.727ValGlu: 4.727 ± 0.074	3.03ValPhe: 3.03 ± 0.059	5.103ValGly: 5.103 ± 0.07	1.48ValHis: 1.48 ± 0.036	4.382ValIle: 4.382 ± 0.069	3.303ValLys: 3.303 ± 0.064	7.041ValLeu: 7.041 ± 0.092	1.943ValMet: 1.943 ± 0.05	2.508ValAsn: 2.508 ± 0.05	2.971ValPro: 2.971 ± 0.051	2.155ValGln: 2.155 ± 0.054	3.922ValArg: 3.922 ± 0.06	4.565ValSer: 4.565 ± 0.073	3.983ValThr: 3.983 ± 0.069	5.404ValVal: 5.404 ± 0.081	0.703ValTrp: 0.703 ± 0.03	1.688ValTyr: 1.688 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	0.879TrpAla: 0.879 ± 0.029	0.149TrpCys: 0.149 ± 0.013	0.654TrpAsp: 0.654 ± 0.023	0.759TrpGlu: 0.759 ± 0.026	0.506TrpPhe: 0.506 ± 0.024	0.863TrpGly: 0.863 ± 0.029	0.28TrpHis: 0.28 ± 0.016	0.653TrpIle: 0.653 ± 0.029	0.633TrpLys: 0.633 ± 0.025	1.228TrpLeu: 1.228 ± 0.038	0.345TrpMet: 0.345 ± 0.019	0.451TrpAsn: 0.451 ± 0.022	0.549TrpPro: 0.549 ± 0.026	0.464TrpGln: 0.464 ± 0.02	0.641TrpArg: 0.641 ± 0.024	0.557TrpSer: 0.557 ± 0.026	0.631TrpThr: 0.631 ± 0.028	0.766TrpVal: 0.766 ± 0.025	0.192TrpTrp: 0.192 ± 0.013	0.283TrpTyr: 0.283 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.2TyrAla: 2.2 ± 0.044	0.39TyrCys: 0.39 ± 0.019	1.63TyrAsp: 1.63 ± 0.043	1.708TyrGlu: 1.708 ± 0.034	1.305TyrPhe: 1.305 ± 0.034	2.214TyrGly: 2.214 ± 0.046	0.576TyrHis: 0.576 ± 0.021	1.441TyrIle: 1.441 ± 0.04	1.282TyrLys: 1.282 ± 0.036	2.758TyrLeu: 2.758 ± 0.052	0.707TyrMet: 0.707 ± 0.026	0.891TyrAsn: 0.891 ± 0.03	1.317TyrPro: 1.317 ± 0.039	0.925TyrGln: 0.925 ± 0.033	1.605TyrArg: 1.605 ± 0.04	1.776TyrSer: 1.776 ± 0.039	1.522TyrThr: 1.522 ± 0.04	1.723TyrVal: 1.723 ± 0.043	0.367TyrTrp: 0.367 ± 0.021	0.874TyrTyr: 0.874 ± 0.032	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3342 proteins (1080842 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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