Amino acid dipepetide frequency for Chloropicon primus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.421AlaAla: 8.421 ± 0.07	1.572AlaCys: 1.572 ± 0.038	3.642AlaAsp: 3.642 ± 0.04	5.947AlaGlu: 5.947 ± 0.058	3.084AlaPhe: 3.084 ± 0.034	6.267AlaGly: 6.267 ± 0.054	1.429AlaHis: 1.429 ± 0.025	3.286AlaIle: 3.286 ± 0.031	5.469AlaLys: 5.469 ± 0.054	8.193AlaLeu: 8.193 ± 0.067	2.15AlaMet: 2.15 ± 0.026	2.519AlaAsn: 2.519 ± 0.027	3.291AlaPro: 3.291 ± 0.042	2.945AlaGln: 2.945 ± 0.029	5.046AlaArg: 5.046 ± 0.05	7.234AlaSer: 7.234 ± 0.055	4.35AlaThr: 4.35 ± 0.039	5.626AlaVal: 5.626 ± 0.047	0.972AlaTrp: 0.972 ± 0.028	1.99AlaTyr: 1.99 ± 0.029	0.0AlaXaa: 0.0 ± 0.0
Cys	1.266CysAla: 1.266 ± 0.033	0.425CysCys: 0.425 ± 0.012	0.9CysAsp: 0.9 ± 0.016	1.063CysGlu: 1.063 ± 0.023	0.767CysPhe: 0.767 ± 0.015	1.44CysGly: 1.44 ± 0.023	0.379CysHis: 0.379 ± 0.009	0.817CysIle: 0.817 ± 0.017	1.031CysLys: 1.031 ± 0.021	1.725CysLeu: 1.725 ± 0.025	0.417CysMet: 0.417 ± 0.012	0.548CysAsn: 0.548 ± 0.011	0.848CysPro: 0.848 ± 0.045	0.547CysGln: 0.547 ± 0.013	0.972CysArg: 0.972 ± 0.049	1.472CysSer: 1.472 ± 0.035	0.981CysThr: 0.981 ± 0.049	1.296CysVal: 1.296 ± 0.035	0.228CysTrp: 0.228 ± 0.008	0.448CysTyr: 0.448 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	4.537AspAla: 4.537 ± 0.037	0.95AspCys: 0.95 ± 0.052	3.473AspAsp: 3.473 ± 0.052	4.314AspGlu: 4.314 ± 0.036	2.319AspPhe: 2.319 ± 0.032	4.216AspGly: 4.216 ± 0.037	1.118AspHis: 1.118 ± 0.022	2.451AspIle: 2.451 ± 0.029	3.034AspLys: 3.034 ± 0.034	5.646AspLeu: 5.646 ± 0.047	1.327AspMet: 1.327 ± 0.019	1.628AspAsn: 1.628 ± 0.03	2.552AspPro: 2.552 ± 0.031	1.725AspGln: 1.725 ± 0.021	2.601AspArg: 2.601 ± 0.029	3.66AspSer: 3.66 ± 0.036	2.286AspThr: 2.286 ± 0.027	4.037AspVal: 4.037 ± 0.037	0.754AspTrp: 0.754 ± 0.015	1.53AspTyr: 1.53 ± 0.022	0.0AspXaa: 0.0 ± 0.0
Glu	7.0GluAla: 7.0 ± 0.062	1.043GluCys: 1.043 ± 0.025	4.954GluAsp: 4.954 ± 0.04	8.952GluGlu: 8.952 ± 0.097	2.166GluPhe: 2.166 ± 0.025	6.238GluGly: 6.238 ± 0.05	1.286GluHis: 1.286 ± 0.019	3.158GluIle: 3.158 ± 0.036	5.112GluLys: 5.112 ± 0.056	6.146GluLeu: 6.146 ± 0.058	1.817GluMet: 1.817 ± 0.023	2.731GluAsn: 2.731 ± 0.028	2.235GluPro: 2.235 ± 0.029	2.541GluGln: 2.541 ± 0.033	4.814GluArg: 4.814 ± 0.05	5.052GluSer: 5.052 ± 0.044	3.399GluThr: 3.399 ± 0.034	5.244GluVal: 5.244 ± 0.04	0.832GluTrp: 0.832 ± 0.015	1.804GluTyr: 1.804 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	2.856PheAla: 2.856 ± 0.027	0.732PheCys: 0.732 ± 0.014	2.32PheAsp: 2.32 ± 0.028	2.523PheGlu: 2.523 ± 0.027	1.578PhePhe: 1.578 ± 0.021	3.069PheGly: 3.069 ± 0.04	0.825PheHis: 0.825 ± 0.015	1.336PheIle: 1.336 ± 0.023	1.955PheLys: 1.955 ± 0.021	3.565PheLeu: 3.565 ± 0.038	0.852PheMet: 0.852 ± 0.013	1.268PheAsn: 1.268 ± 0.018	1.473PhePro: 1.473 ± 0.023	1.412PheGln: 1.412 ± 0.021	1.811PheArg: 1.811 ± 0.021	2.922PheSer: 2.922 ± 0.032	1.81PheThr: 1.81 ± 0.027	2.8PheVal: 2.8 ± 0.032	0.499PheTrp: 0.499 ± 0.013	1.02PheTyr: 1.02 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	6.316GlyAla: 6.316 ± 0.057	1.28GlyCys: 1.28 ± 0.057	4.334GlyAsp: 4.334 ± 0.044	5.766GlyGlu: 5.766 ± 0.046	2.724GlyPhe: 2.724 ± 0.033	8.891GlyGly: 8.891 ± 0.097	1.592GlyHis: 1.592 ± 0.027	3.041GlyIle: 3.041 ± 0.033	5.186GlyLys: 5.186 ± 0.041	6.445GlyLeu: 6.445 ± 0.052	1.848GlyMet: 1.848 ± 0.028	2.647GlyAsn: 2.647 ± 0.033	2.567GlyPro: 2.567 ± 0.027	2.609GlyGln: 2.609 ± 0.03	4.678GlyArg: 4.678 ± 0.046	6.564GlySer: 6.564 ± 0.053	3.968GlyThr: 3.968 ± 0.042	5.233GlyVal: 5.233 ± 0.043	0.903GlyTrp: 0.903 ± 0.017	1.969GlyTyr: 1.969 ± 0.035	0.0GlyXaa: 0.0 ± 0.0
His	1.552HisAla: 1.552 ± 0.023	0.412HisCys: 0.412 ± 0.01	0.98HisAsp: 0.98 ± 0.027	1.25HisGlu: 1.25 ± 0.02	0.874HisPhe: 0.874 ± 0.016	1.503HisGly: 1.503 ± 0.022	0.702HisHis: 0.702 ± 0.018	0.867HisIle: 0.867 ± 0.016	1.215HisLys: 1.215 ± 0.038	2.14HisLeu: 2.14 ± 0.03	0.526HisMet: 0.526 ± 0.013	0.697HisAsn: 0.697 ± 0.025	1.018HisPro: 1.018 ± 0.019	0.852HisGln: 0.852 ± 0.016	1.177HisArg: 1.177 ± 0.022	1.424HisSer: 1.424 ± 0.02	0.941HisThr: 0.941 ± 0.016	1.457HisVal: 1.457 ± 0.019	0.291HisTrp: 0.291 ± 0.009	0.608HisTyr: 0.608 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	3.376IleAla: 3.376 ± 0.034	0.754IleCys: 0.754 ± 0.016	2.34IleAsp: 2.34 ± 0.027	2.945IleGlu: 2.945 ± 0.031	1.615IlePhe: 1.615 ± 0.024	2.598IleGly: 2.598 ± 0.028	0.935IleHis: 0.935 ± 0.019	1.634IleIle: 1.634 ± 0.021	2.35IleLys: 2.35 ± 0.03	4.046IleLeu: 4.046 ± 0.041	0.94IleMet: 0.94 ± 0.017	1.291IleAsn: 1.291 ± 0.02	1.955IlePro: 1.955 ± 0.022	1.644IleGln: 1.644 ± 0.022	2.078IleArg: 2.078 ± 0.026	3.02IleSer: 3.02 ± 0.032	1.974IleThr: 1.974 ± 0.03	2.915IleVal: 2.915 ± 0.031	0.444IleTrp: 0.444 ± 0.011	1.02IleTyr: 1.02 ± 0.015	0.0IleXaa: 0.0 ± 0.0
Lys	5.429LysAla: 5.429 ± 0.049	0.898LysCys: 0.898 ± 0.022	3.499LysAsp: 3.499 ± 0.034	5.525LysGlu: 5.525 ± 0.062	1.968LysPhe: 1.968 ± 0.023	4.634LysGly: 4.634 ± 0.042	1.326LysHis: 1.326 ± 0.023	2.545LysIle: 2.545 ± 0.029	5.401LysLys: 5.401 ± 0.062	5.59LysLeu: 5.59 ± 0.045	1.562LysMet: 1.562 ± 0.025	2.115LysAsn: 2.115 ± 0.046	2.484LysPro: 2.484 ± 0.033	2.552LysGln: 2.552 ± 0.031	4.211LysArg: 4.211 ± 0.041	4.32LysSer: 4.32 ± 0.038	3.066LysThr: 3.066 ± 0.035	4.546LysVal: 4.546 ± 0.038	0.75LysTrp: 0.75 ± 0.014	1.689LysTyr: 1.689 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	7.548LeuAla: 7.548 ± 0.061	1.8LeuCys: 1.8 ± 0.027	5.262LeuAsp: 5.262 ± 0.04	7.306LeuGlu: 7.306 ± 0.06	3.221LeuPhe: 3.221 ± 0.032	6.792LeuGly: 6.792 ± 0.054	2.12LeuHis: 2.12 ± 0.027	3.114LeuIle: 3.114 ± 0.033	5.928LeuLys: 5.928 ± 0.049	9.066LeuLeu: 9.066 ± 0.078	2.05LeuMet: 2.05 ± 0.027	3.123LeuAsn: 3.123 ± 0.032	4.062LeuPro: 4.062 ± 0.033	4.133LeuGln: 4.133 ± 0.046	5.785LeuArg: 5.785 ± 0.05	7.488LeuSer: 7.488 ± 0.057	4.177LeuThr: 4.177 ± 0.039	6.634LeuVal: 6.634 ± 0.056	1.031LeuTrp: 1.031 ± 0.018	2.335LeuTyr: 2.335 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	2.14MetAla: 2.14 ± 0.023	0.37MetCys: 0.37 ± 0.009	1.362MetAsp: 1.362 ± 0.018	1.896MetGlu: 1.896 ± 0.026	0.769MetPhe: 0.769 ± 0.015	1.672MetGly: 1.672 ± 0.026	0.497MetHis: 0.497 ± 0.012	0.966MetIle: 0.966 ± 0.017	1.732MetLys: 1.732 ± 0.024	2.098MetLeu: 2.098 ± 0.026	0.746MetMet: 0.746 ± 0.015	0.955MetAsn: 0.955 ± 0.023	1.023MetPro: 1.023 ± 0.021	1.046MetGln: 1.046 ± 0.021	1.468MetArg: 1.468 ± 0.021	1.811MetSer: 1.811 ± 0.026	1.256MetThr: 1.256 ± 0.017	1.58MetVal: 1.58 ± 0.019	0.247MetTrp: 0.247 ± 0.009	0.607MetTyr: 0.607 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	2.887AsnAla: 2.887 ± 0.027	0.536AsnCys: 0.536 ± 0.013	1.634AsnAsp: 1.634 ± 0.025	2.222AsnGlu: 2.222 ± 0.027	1.469AsnPhe: 1.469 ± 0.021	2.515AsnGly: 2.515 ± 0.049	0.691AsnHis: 0.691 ± 0.014	1.565AsnIle: 1.565 ± 0.021	2.072AsnLys: 2.072 ± 0.029	3.428AsnLeu: 3.428 ± 0.035	0.916AsnMet: 0.916 ± 0.016	1.373AsnAsn: 1.373 ± 0.033	1.761AsnPro: 1.761 ± 0.025	1.277AsnGln: 1.277 ± 0.018	1.693AsnArg: 1.693 ± 0.031	2.358AsnSer: 2.358 ± 0.027	1.731AsnThr: 1.731 ± 0.027	2.424AsnVal: 2.424 ± 0.023	0.421AsnTrp: 0.421 ± 0.011	0.922AsnTyr: 0.922 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	3.468ProAla: 3.468 ± 0.04	0.698ProCys: 0.698 ± 0.019	2.027ProAsp: 2.027 ± 0.023	3.196ProGlu: 3.196 ± 0.037	1.564ProPhe: 1.564 ± 0.023	3.289ProGly: 3.289 ± 0.04	0.837ProHis: 0.837 ± 0.017	1.477ProIle: 1.477 ± 0.02	2.601ProLys: 2.601 ± 0.031	3.682ProLeu: 3.682 ± 0.033	0.875ProMet: 0.875 ± 0.016	1.349ProAsn: 1.349 ± 0.021	3.035ProPro: 3.035 ± 0.067	1.613ProGln: 1.613 ± 0.024	2.426ProArg: 2.426 ± 0.027	3.852ProSer: 3.852 ± 0.042	2.189ProThr: 2.189 ± 0.032	2.869ProVal: 2.869 ± 0.046	0.593ProTrp: 0.593 ± 0.015	1.101ProTyr: 1.101 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	3.331GlnAla: 3.331 ± 0.037	0.62GlnCys: 0.62 ± 0.04	1.939GlnAsp: 1.939 ± 0.025	2.934GlnGlu: 2.934 ± 0.033	1.112GlnPhe: 1.112 ± 0.017	2.855GlnGly: 2.855 ± 0.028	0.832GlnHis: 0.832 ± 0.016	1.545GlnIle: 1.545 ± 0.023	2.441GlnLys: 2.441 ± 0.031	3.271GlnLeu: 3.271 ± 0.034	1.002GlnMet: 1.002 ± 0.018	1.403GlnAsn: 1.403 ± 0.02	1.462GlnPro: 1.462 ± 0.048	2.382GlnGln: 2.382 ± 0.043	2.428GlnArg: 2.428 ± 0.029	2.501GlnSer: 2.501 ± 0.031	1.731GlnThr: 1.731 ± 0.023	2.752GlnVal: 2.752 ± 0.029	0.49GlnTrp: 0.49 ± 0.015	0.931GlnTyr: 0.931 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	4.658ArgAla: 4.658 ± 0.045	1.01ArgCys: 1.01 ± 0.038	3.071ArgAsp: 3.071 ± 0.034	4.773ArgGlu: 4.773 ± 0.056	1.844ArgPhe: 1.844 ± 0.023	4.727ArgGly: 4.727 ± 0.052	1.196ArgHis: 1.196 ± 0.018	2.382ArgIle: 2.382 ± 0.023	4.235ArgLys: 4.235 ± 0.044	5.002ArgLeu: 5.002 ± 0.036	1.443ArgMet: 1.443 ± 0.021	1.98ArgAsn: 1.98 ± 0.026	2.245ArgPro: 2.245 ± 0.028	2.215ArgGln: 2.215 ± 0.027	4.974ArgArg: 4.974 ± 0.053	4.47ArgSer: 4.47 ± 0.049	2.971ArgThr: 2.971 ± 0.032	3.975ArgVal: 3.975 ± 0.038	0.728ArgTrp: 0.728 ± 0.015	1.459ArgTyr: 1.459 ± 0.021	0.0ArgXaa: 0.0 ± 0.0
Ser	6.043SerAla: 6.043 ± 0.051	1.415SerCys: 1.415 ± 0.033	3.776SerAsp: 3.776 ± 0.035	5.028SerGlu: 5.028 ± 0.036	3.126SerPhe: 3.126 ± 0.036	6.397SerGly: 6.397 ± 0.063	1.497SerHis: 1.497 ± 0.021	3.16SerIle: 3.16 ± 0.034	4.947SerLys: 4.947 ± 0.039	7.488SerLeu: 7.488 ± 0.056	1.937SerMet: 1.937 ± 0.024	2.642SerAsn: 2.642 ± 0.03	3.726SerPro: 3.726 ± 0.045	2.896SerGln: 2.896 ± 0.034	4.396SerArg: 4.396 ± 0.04	8.626SerSer: 8.626 ± 0.09	4.154SerThr: 4.154 ± 0.042	5.143SerVal: 5.143 ± 0.05	1.001SerTrp: 1.001 ± 0.018	1.889SerTyr: 1.889 ± 0.027	0.0SerXaa: 0.0 ± 0.0
Thr	3.903ThrAla: 3.903 ± 0.04	1.037ThrCys: 1.037 ± 0.024	2.161ThrAsp: 2.161 ± 0.027	3.072ThrGlu: 3.072 ± 0.026	2.113ThrPhe: 2.113 ± 0.029	3.746ThrGly: 3.746 ± 0.049	0.894ThrHis: 0.894 ± 0.015	2.219ThrIle: 2.219 ± 0.027	3.073ThrLys: 3.073 ± 0.032	4.696ThrLeu: 4.696 ± 0.04	1.262ThrMet: 1.262 ± 0.02	1.681ThrAsn: 1.681 ± 0.035	2.513ThrPro: 2.513 ± 0.035	1.613ThrGln: 1.613 ± 0.023	2.828ThrArg: 2.828 ± 0.032	4.311ThrSer: 4.311 ± 0.043	3.394ThrThr: 3.394 ± 0.055	3.489ThrVal: 3.489 ± 0.047	0.614ThrTrp: 0.614 ± 0.015	1.353ThrTyr: 1.353 ± 0.028	0.0ThrXaa: 0.0 ± 0.0
Val	5.966ValAla: 5.966 ± 0.04	1.283ValCys: 1.283 ± 0.019	4.091ValAsp: 4.091 ± 0.048	5.296ValGlu: 5.296 ± 0.044	2.675ValPhe: 2.675 ± 0.032	4.934ValGly: 4.934 ± 0.041	1.463ValHis: 1.463 ± 0.02	2.709ValIle: 2.709 ± 0.031	4.047ValLys: 4.047 ± 0.037	7.071ValLeu: 7.071 ± 0.055	1.624ValMet: 1.624 ± 0.022	2.309ValAsn: 2.309 ± 0.027	3.104ValPro: 3.104 ± 0.032	2.613ValGln: 2.613 ± 0.026	3.793ValArg: 3.793 ± 0.035	5.301ValSer: 5.301 ± 0.048	3.592ValThr: 3.592 ± 0.045	5.84ValVal: 5.84 ± 0.051	0.825ValTrp: 0.825 ± 0.016	1.849ValTyr: 1.849 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	0.797TrpAla: 0.797 ± 0.017	0.221TrpCys: 0.221 ± 0.007	0.774TrpAsp: 0.774 ± 0.021	0.772TrpGlu: 0.772 ± 0.016	0.457TrpPhe: 0.457 ± 0.011	0.774TrpGly: 0.774 ± 0.026	0.279TrpHis: 0.279 ± 0.009	0.551TrpIle: 0.551 ± 0.013	0.817TrpLys: 0.817 ± 0.018	1.181TrpLeu: 1.181 ± 0.022	0.326TrpMet: 0.326 ± 0.009	0.56TrpAsn: 0.56 ± 0.011	0.409TrpPro: 0.409 ± 0.011	0.44TrpGln: 0.44 ± 0.009	0.847TrpArg: 0.847 ± 0.016	0.984TrpSer: 0.984 ± 0.017	0.675TrpThr: 0.675 ± 0.014	0.761TrpVal: 0.761 ± 0.012	0.197TrpTrp: 0.197 ± 0.007	0.332TrpTyr: 0.332 ± 0.008	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.939TyrAla: 1.939 ± 0.037	0.51TyrCys: 0.51 ± 0.012	1.617TyrAsp: 1.617 ± 0.023	1.746TyrGlu: 1.746 ± 0.023	1.179TyrPhe: 1.179 ± 0.019	2.002TyrGly: 2.002 ± 0.042	0.587TyrHis: 0.587 ± 0.013	1.051TyrIle: 1.051 ± 0.014	1.464TyrLys: 1.464 ± 0.037	2.493TyrLeu: 2.493 ± 0.031	0.625TyrMet: 0.625 ± 0.012	1.075TyrAsn: 1.075 ± 0.016	0.98TyrPro: 0.98 ± 0.016	0.906TyrGln: 0.906 ± 0.019	1.335TyrArg: 1.335 ± 0.02	1.916TyrSer: 1.916 ± 0.031	1.329TyrThr: 1.329 ± 0.026	1.764TyrVal: 1.764 ± 0.027	0.336TyrTrp: 0.336 ± 0.009	0.837TyrTyr: 0.837 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8606 proteins (4253573 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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