Amino acid dipepetide frequency for Bryocella elongata

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
15.149AlaAla: 15.149 ± 0.152
0.98AlaCys: 0.98 ± 0.025
5.238AlaAsp: 5.238 ± 0.058
6.365AlaGlu: 6.365 ± 0.087
3.797AlaPhe: 3.797 ± 0.063
9.294AlaGly: 9.294 ± 0.105
2.443AlaHis: 2.443 ± 0.04
5.597AlaIle: 5.597 ± 0.067
4.176AlaLys: 4.176 ± 0.065
11.259AlaLeu: 11.259 ± 0.11
3.205AlaMet: 3.205 ± 0.055
3.535AlaAsn: 3.535 ± 0.058
5.925AlaPro: 5.925 ± 0.087
4.642AlaGln: 4.642 ± 0.065
6.274AlaArg: 6.274 ± 0.08
7.414AlaSer: 7.414 ± 0.089
7.395AlaThr: 7.395 ± 0.12
7.996AlaVal: 7.996 ± 0.073
1.454AlaTrp: 1.454 ± 0.031
2.574AlaTyr: 2.574 ± 0.042
0.0AlaXaa: 0.0 ± 0.0
Cys
0.934CysAla: 0.934 ± 0.028
0.137CysCys: 0.137 ± 0.01
0.424CysAsp: 0.424 ± 0.017
0.406CysGlu: 0.406 ± 0.015
0.367CysPhe: 0.367 ± 0.014
0.921CysGly: 0.921 ± 0.026
0.238CysHis: 0.238 ± 0.019
0.391CysIle: 0.391 ± 0.015
0.223CysLys: 0.223 ± 0.012
0.808CysLeu: 0.808 ± 0.024
0.185CysMet: 0.185 ± 0.009
0.271CysAsn: 0.271 ± 0.013
0.426CysPro: 0.426 ± 0.018
0.209CysGln: 0.209 ± 0.012
0.442CysArg: 0.442 ± 0.019
0.611CysSer: 0.611 ± 0.021
0.575CysThr: 0.575 ± 0.025
0.654CysVal: 0.654 ± 0.019
0.119CysTrp: 0.119 ± 0.01
0.232CysTyr: 0.232 ± 0.012
0.0CysXaa: 0.0 ± 0.0
Asp
6.06AspAla: 6.06 ± 0.067
0.4AspCys: 0.4 ± 0.018
2.631AspAsp: 2.631 ± 0.046
2.995AspGlu: 2.995 ± 0.054
2.07AspPhe: 2.07 ± 0.035
4.544AspGly: 4.544 ± 0.074
1.24AspHis: 1.24 ± 0.028
2.246AspIle: 2.246 ± 0.036
1.704AspLys: 1.704 ± 0.039
5.075AspLeu: 5.075 ± 0.06
0.964AspMet: 0.964 ± 0.025
1.438AspAsn: 1.438 ± 0.032
3.36AspPro: 3.36 ± 0.053
1.704AspGln: 1.704 ± 0.037
3.192AspArg: 3.192 ± 0.047
2.771AspSer: 2.771 ± 0.046
2.677AspThr: 2.677 ± 0.041
3.746AspVal: 3.746 ± 0.054
0.813AspTrp: 0.813 ± 0.026
1.529AspTyr: 1.529 ± 0.03
0.0AspXaa: 0.0 ± 0.0
Glu
6.109GluAla: 6.109 ± 0.088
0.364GluCys: 0.364 ± 0.016
2.624GluAsp: 2.624 ± 0.044
2.957GluGlu: 2.957 ± 0.064
1.924GluPhe: 1.924 ± 0.034
3.73GluGly: 3.73 ± 0.05
1.452GluHis: 1.452 ± 0.03
2.895GluIle: 2.895 ± 0.05
2.022GluLys: 2.022 ± 0.041
5.633GluLeu: 5.633 ± 0.081
1.427GluMet: 1.427 ± 0.032
1.483GluAsn: 1.483 ± 0.034
2.493GluPro: 2.493 ± 0.047
2.401GluGln: 2.401 ± 0.043
4.089GluArg: 4.089 ± 0.068
2.928GluSer: 2.928 ± 0.056
2.912GluThr: 2.912 ± 0.039
3.693GluVal: 3.693 ± 0.054
0.703GluTrp: 0.703 ± 0.02
1.33GluTyr: 1.33 ± 0.029
0.0GluXaa: 0.0 ± 0.0
Phe
4.418PheAla: 4.418 ± 0.062
0.361PheCys: 0.361 ± 0.015
2.454PheAsp: 2.454 ± 0.044
1.916PheGlu: 1.916 ± 0.038
1.571PhePhe: 1.571 ± 0.038
3.586PheGly: 3.586 ± 0.057
0.999PheHis: 0.999 ± 0.028
1.309PheIle: 1.309 ± 0.033
0.962PheLys: 0.962 ± 0.028
3.563PheLeu: 3.563 ± 0.055
0.689PheMet: 0.689 ± 0.02
1.388PheAsn: 1.388 ± 0.04
1.782PhePro: 1.782 ± 0.038
1.201PheGln: 1.201 ± 0.025
2.211PheArg: 2.211 ± 0.033
2.627PheSer: 2.627 ± 0.044
2.485PheThr: 2.485 ± 0.051
2.676PheVal: 2.676 ± 0.042
0.51PheTrp: 0.51 ± 0.02
1.174PheTyr: 1.174 ± 0.029
0.0PheXaa: 0.0 ± 0.0
Gly
8.327GlyAla: 8.327 ± 0.128
0.866GlyCys: 0.866 ± 0.024
4.022GlyAsp: 4.022 ± 0.052
3.96GlyGlu: 3.96 ± 0.056
3.45GlyPhe: 3.45 ± 0.049
6.95GlyGly: 6.95 ± 0.108
1.943GlyHis: 1.943 ± 0.032
4.178GlyIle: 4.178 ± 0.052
3.404GlyLys: 3.404 ± 0.054
7.553GlyLeu: 7.553 ± 0.073
2.087GlyMet: 2.087 ± 0.035
2.735GlyAsn: 2.735 ± 0.063
3.478GlyPro: 3.478 ± 0.061
2.816GlyGln: 2.816 ± 0.044
4.518GlyArg: 4.518 ± 0.058
5.688GlySer: 5.688 ± 0.091
5.554GlyThr: 5.554 ± 0.122
5.991GlyVal: 5.991 ± 0.071
1.306GlyTrp: 1.306 ± 0.032
2.631GlyTyr: 2.631 ± 0.048
0.0GlyXaa: 0.0 ± 0.0
His
2.522HisAla: 2.522 ± 0.042
0.219HisCys: 0.219 ± 0.011
1.261HisAsp: 1.261 ± 0.027
1.267HisGlu: 1.267 ± 0.029
1.034HisPhe: 1.034 ± 0.027
2.101HisGly: 2.101 ± 0.035
0.661HisHis: 0.661 ± 0.023
1.063HisIle: 1.063 ± 0.028
0.617HisLys: 0.617 ± 0.02
2.304HisLeu: 2.304 ± 0.037
0.493HisMet: 0.493 ± 0.016
0.677HisAsn: 0.677 ± 0.019
1.546HisPro: 1.546 ± 0.037
0.728HisGln: 0.728 ± 0.018
1.409HisArg: 1.409 ± 0.036
1.295HisSer: 1.295 ± 0.028
1.322HisThr: 1.322 ± 0.028
1.668HisVal: 1.668 ± 0.034
0.394HisTrp: 0.394 ± 0.015
0.689HisTyr: 0.689 ± 0.02
0.0HisXaa: 0.0 ± 0.0
Ile
6.32IleAla: 6.32 ± 0.064
0.406IleCys: 0.406 ± 0.017
2.971IleAsp: 2.971 ± 0.045
2.869IleGlu: 2.869 ± 0.047
1.813IlePhe: 1.813 ± 0.034
3.986IleGly: 3.986 ± 0.053
1.038IleHis: 1.038 ± 0.028
1.65IleIle: 1.65 ± 0.041
1.284IleLys: 1.284 ± 0.034
4.082IleLeu: 4.082 ± 0.054
0.703IleMet: 0.703 ± 0.026
1.496IleAsn: 1.496 ± 0.034
2.626IlePro: 2.626 ± 0.039
1.412IleGln: 1.412 ± 0.033
2.708IleArg: 2.708 ± 0.045
3.079IleSer: 3.079 ± 0.049
3.119IleThr: 3.119 ± 0.054
3.676IleVal: 3.676 ± 0.051
0.499IleTrp: 0.499 ± 0.017
1.289IleTyr: 1.289 ± 0.024
0.0IleXaa: 0.0 ± 0.0
Lys
3.777LysAla: 3.777 ± 0.068
0.18LysCys: 0.18 ± 0.012
1.844LysAsp: 1.844 ± 0.034
1.657LysGlu: 1.657 ± 0.04
1.08LysPhe: 1.08 ± 0.028
2.376LysGly: 2.376 ± 0.042
0.779LysHis: 0.779 ± 0.021
1.691LysIle: 1.691 ± 0.035
1.485LysLys: 1.485 ± 0.045
3.792LysLeu: 3.792 ± 0.053
0.912LysMet: 0.912 ± 0.026
1.097LysAsn: 1.097 ± 0.027
2.282LysPro: 2.282 ± 0.047
1.364LysGln: 1.364 ± 0.034
2.049LysArg: 2.049 ± 0.035
1.933LysSer: 1.933 ± 0.035
2.138LysThr: 2.138 ± 0.037
2.466LysVal: 2.466 ± 0.046
0.371LysTrp: 0.371 ± 0.014
0.896LysTyr: 0.896 ± 0.024
0.0LysXaa: 0.0 ± 0.0
Leu
11.89LeuAla: 11.89 ± 0.117
0.995LeuCys: 0.995 ± 0.028
5.168LeuAsp: 5.168 ± 0.062
5.348LeuGlu: 5.348 ± 0.082
3.404LeuPhe: 3.404 ± 0.055
7.468LeuGly: 7.468 ± 0.071
2.379LeuHis: 2.379 ± 0.04
4.266LeuIle: 4.266 ± 0.059
3.468LeuLys: 3.468 ± 0.057
10.162LeuLeu: 10.162 ± 0.126
2.076LeuMet: 2.076 ± 0.042
3.165LeuAsn: 3.165 ± 0.05
5.787LeuPro: 5.787 ± 0.062
3.316LeuGln: 3.316 ± 0.049
6.92LeuArg: 6.92 ± 0.088
6.443LeuSer: 6.443 ± 0.068
6.328LeuThr: 6.328 ± 0.078
6.554LeuVal: 6.554 ± 0.072
1.317LeuTrp: 1.317 ± 0.034
2.494LeuTyr: 2.494 ± 0.035
0.0LeuXaa: 0.0 ± 0.0
Met
2.524MetAla: 2.524 ± 0.041
0.142MetCys: 0.142 ± 0.008
1.039MetAsp: 1.039 ± 0.026
1.125MetGlu: 1.125 ± 0.027
0.695MetPhe: 0.695 ± 0.022
1.677MetGly: 1.677 ± 0.032
0.564MetHis: 0.564 ± 0.018
1.04MetIle: 1.04 ± 0.024
1.05MetLys: 1.05 ± 0.028
2.457MetLeu: 2.457 ± 0.047
0.591MetMet: 0.591 ± 0.02
0.792MetAsn: 0.792 ± 0.02
1.431MetPro: 1.431 ± 0.03
1.011MetGln: 1.011 ± 0.028
1.62MetArg: 1.62 ± 0.03
1.542MetSer: 1.542 ± 0.03
1.46MetThr: 1.46 ± 0.027
1.552MetVal: 1.552 ± 0.033
0.247MetTrp: 0.247 ± 0.013
0.453MetTyr: 0.453 ± 0.017
0.0MetXaa: 0.0 ± 0.0
Asn
3.609AsnAla: 3.609 ± 0.061
0.267AsnCys: 0.267 ± 0.013
1.648AsnAsp: 1.648 ± 0.028
1.479AsnGlu: 1.479 ± 0.029
1.396AsnPhe: 1.396 ± 0.039
3.15AsnGly: 3.15 ± 0.065
0.698AsnHis: 0.698 ± 0.018
1.551AsnIle: 1.551 ± 0.036
0.827AsnLys: 0.827 ± 0.026
3.069AsnLeu: 3.069 ± 0.044
0.598AsnMet: 0.598 ± 0.018
1.137AsnAsn: 1.137 ± 0.042
2.266AsnPro: 2.266 ± 0.049
1.12AsnGln: 1.12 ± 0.039
1.65AsnArg: 1.65 ± 0.034
2.041AsnSer: 2.041 ± 0.053
1.994AsnThr: 1.994 ± 0.049
2.513AsnVal: 2.513 ± 0.045
0.434AsnTrp: 0.434 ± 0.019
1.139AsnTyr: 1.139 ± 0.037
0.0AsnXaa: 0.0 ± 0.0
Pro
6.678ProAla: 6.678 ± 0.085
0.359ProCys: 0.359 ± 0.016
3.045ProAsp: 3.045 ± 0.05
3.517ProGlu: 3.517 ± 0.053
1.954ProPhe: 1.954 ± 0.039
4.734ProGly: 4.734 ± 0.06
1.245ProHis: 1.245 ± 0.03
2.371ProIle: 2.371 ± 0.037
1.926ProLys: 1.926 ± 0.038
4.831ProLeu: 4.831 ± 0.056
1.223ProMet: 1.223 ± 0.027
1.888ProAsn: 1.888 ± 0.043
2.614ProPro: 2.614 ± 0.064
2.215ProGln: 2.215 ± 0.045
2.767ProArg: 2.767 ± 0.049
3.586ProSer: 3.586 ± 0.049
3.446ProThr: 3.446 ± 0.06
4.158ProVal: 4.158 ± 0.055
0.772ProTrp: 0.772 ± 0.022
1.441ProTyr: 1.441 ± 0.027
0.0ProXaa: 0.0 ± 0.0
Gln
3.918GlnAla: 3.918 ± 0.058
0.229GlnCys: 0.229 ± 0.012
1.575GlnAsp: 1.575 ± 0.029
1.603GlnGlu: 1.603 ± 0.04
1.323GlnPhe: 1.323 ± 0.03
2.58GlnGly: 2.58 ± 0.056
0.931GlnHis: 0.931 ± 0.025
1.84GlnIle: 1.84 ± 0.035
1.234GlnLys: 1.234 ± 0.032
3.649GlnLeu: 3.649 ± 0.054
0.993GlnMet: 0.993 ± 0.027
1.12GlnAsn: 1.12 ± 0.032
2.289GlnPro: 2.289 ± 0.044
2.102GlnGln: 2.102 ± 0.045
2.671GlnArg: 2.671 ± 0.048
2.285GlnSer: 2.285 ± 0.047
2.306GlnThr: 2.306 ± 0.049
2.641GlnVal: 2.641 ± 0.041
0.481GlnTrp: 0.481 ± 0.017
0.997GlnTyr: 0.997 ± 0.029
0.0GlnXaa: 0.0 ± 0.0
Arg
5.953ArgAla: 5.953 ± 0.072
0.479ArgCys: 0.479 ± 0.017
3.167ArgAsp: 3.167 ± 0.049
3.834ArgGlu: 3.834 ± 0.065
2.525ArgPhe: 2.525 ± 0.041
4.069ArgGly: 4.069 ± 0.059
1.346ArgHis: 1.346 ± 0.029
3.401ArgIle: 3.401 ± 0.042
2.216ArgLys: 2.216 ± 0.043
5.85ArgLeu: 5.85 ± 0.073
1.689ArgMet: 1.689 ± 0.031
2.079ArgAsn: 2.079 ± 0.038
2.903ArgPro: 2.903 ± 0.052
2.116ArgGln: 2.116 ± 0.039
4.286ArgArg: 4.286 ± 0.065
3.925ArgSer: 3.925 ± 0.062
3.435ArgThr: 3.435 ± 0.043
4.541ArgVal: 4.541 ± 0.061
1.029ArgTrp: 1.029 ± 0.03
1.88ArgTyr: 1.88 ± 0.038
0.0ArgXaa: 0.0 ± 0.0
Ser
7.077SerAla: 7.077 ± 0.094
0.587SerCys: 0.587 ± 0.023
3.002SerAsp: 3.002 ± 0.044
3.036SerGlu: 3.036 ± 0.055
2.73SerPhe: 2.73 ± 0.046
6.128SerGly: 6.128 ± 0.103
1.399SerHis: 1.399 ± 0.027
3.147SerIle: 3.147 ± 0.047
1.917SerLys: 1.917 ± 0.038
6.402SerLeu: 6.402 ± 0.073
1.417SerMet: 1.417 ± 0.032
2.184SerAsn: 2.184 ± 0.047
3.485SerPro: 3.485 ± 0.051
2.251SerGln: 2.251 ± 0.039
3.491SerArg: 3.491 ± 0.052
4.849SerSer: 4.849 ± 0.097
4.349SerThr: 4.349 ± 0.083
4.498SerVal: 4.498 ± 0.062
0.841SerTrp: 0.841 ± 0.026
1.85SerTyr: 1.85 ± 0.039
0.0SerXaa: 0.0 ± 0.0
Thr
7.114ThrAla: 7.114 ± 0.105
0.544ThrCys: 0.544 ± 0.022
2.872ThrAsp: 2.872 ± 0.051
2.862ThrGlu: 2.862 ± 0.043
2.426ThrPhe: 2.426 ± 0.045
5.723ThrGly: 5.723 ± 0.128
1.37ThrHis: 1.37 ± 0.031
3.163ThrIle: 3.163 ± 0.061
1.796ThrLys: 1.796 ± 0.034
6.724ThrLeu: 6.724 ± 0.078
1.248ThrMet: 1.248 ± 0.027
2.12ThrAsn: 2.12 ± 0.056
4.259ThrPro: 4.259 ± 0.062
2.132ThrGln: 2.132 ± 0.035
3.219ThrArg: 3.219 ± 0.045
4.216ThrSer: 4.216 ± 0.093
4.171ThrThr: 4.171 ± 0.095
4.894ThrVal: 4.894 ± 0.096
0.905ThrTrp: 0.905 ± 0.025
1.705ThrTyr: 1.705 ± 0.04
0.0ThrXaa: 0.0 ± 0.0
Val
8.254ValAla: 8.254 ± 0.073
0.692ValCys: 0.692 ± 0.022
3.905ValAsp: 3.905 ± 0.047
3.982ValGlu: 3.982 ± 0.051
2.61ValPhe: 2.61 ± 0.043
5.152ValGly: 5.152 ± 0.06
1.574ValHis: 1.574 ± 0.031
3.387ValIle: 3.387 ± 0.043
2.393ValLys: 2.393 ± 0.044
7.545ValLeu: 7.545 ± 0.075
1.586ValMet: 1.586 ± 0.034
2.36ValAsn: 2.36 ± 0.054
3.884ValPro: 3.884 ± 0.048
2.46ValGln: 2.46 ± 0.041
4.475ValArg: 4.475 ± 0.054
4.705ValSer: 4.705 ± 0.077
5.02ValThr: 5.02 ± 0.092
5.697ValVal: 5.697 ± 0.065
0.965ValTrp: 0.965 ± 0.027
1.812ValTyr: 1.812 ± 0.035
0.0ValXaa: 0.0 ± 0.0
Trp
1.158TrpAla: 1.158 ± 0.029
0.126TrpCys: 0.126 ± 0.01
0.659TrpAsp: 0.659 ± 0.019
0.614TrpGlu: 0.614 ± 0.023
0.55TrpPhe: 0.55 ± 0.019
0.922TrpGly: 0.922 ± 0.024
0.371TrpHis: 0.371 ± 0.015
0.76TrpIle: 0.76 ± 0.026
0.632TrpLys: 0.632 ± 0.02
1.562TrpLeu: 1.562 ± 0.038
0.422TrpMet: 0.422 ± 0.015
0.583TrpAsn: 0.583 ± 0.02
0.588TrpPro: 0.588 ± 0.019
0.626TrpGln: 0.626 ± 0.018
0.909TrpArg: 0.909 ± 0.025
0.906TrpSer: 0.906 ± 0.024
0.925TrpThr: 0.925 ± 0.022
0.909TrpVal: 0.909 ± 0.026
0.241TrpTrp: 0.241 ± 0.012
0.376TrpTyr: 0.376 ± 0.015
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.921TyrAla: 2.921 ± 0.047
0.236TyrCys: 0.236 ± 0.011
1.607TyrAsp: 1.607 ± 0.033
1.377TyrGlu: 1.377 ± 0.028
1.166TyrPhe: 1.166 ± 0.029
2.37TyrGly: 2.37 ± 0.037
0.6TyrHis: 0.6 ± 0.019
1.081TyrIle: 1.081 ± 0.029
0.835TyrLys: 0.835 ± 0.024
2.628TyrLeu: 2.628 ± 0.047
0.503TyrMet: 0.503 ± 0.018
1.036TyrAsn: 1.036 ± 0.038
1.342TyrPro: 1.342 ± 0.032
0.942TyrGln: 0.942 ± 0.026
1.822TyrArg: 1.822 ± 0.041
1.795TyrSer: 1.795 ± 0.037
1.854TyrThr: 1.854 ± 0.048
1.94TyrVal: 1.94 ± 0.033
0.437TyrTrp: 0.437 ± 0.02
0.887TyrTyr: 0.887 ± 0.028
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4503 proteins (1673813 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski