Amino acid dipepetide frequency for Kwoniella bestiolae CBS 10118

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.597AlaAla: 6.597 ± 0.06	0.811AlaCys: 0.811 ± 0.017	3.257AlaAsp: 3.257 ± 0.031	4.619AlaGlu: 4.619 ± 0.045	2.629AlaPhe: 2.629 ± 0.032	5.4AlaGly: 5.4 ± 0.043	1.534AlaHis: 1.534 ± 0.02	3.942AlaIle: 3.942 ± 0.035	3.922AlaLys: 3.922 ± 0.036	6.859AlaLeu: 6.859 ± 0.055	1.658AlaMet: 1.658 ± 0.021	2.578AlaAsn: 2.578 ± 0.028	4.415AlaPro: 4.415 ± 0.051	3.147AlaGln: 3.147 ± 0.034	4.158AlaArg: 4.158 ± 0.031	6.861AlaSer: 6.861 ± 0.047	4.305AlaThr: 4.305 ± 0.039	4.278AlaVal: 4.278 ± 0.033	0.972AlaTrp: 0.972 ± 0.015	1.884AlaTyr: 1.884 ± 0.02	0.0AlaXaa: 0.0 ± 0.0
Cys	0.678CysAla: 0.678 ± 0.015	0.176CysCys: 0.176 ± 0.007	0.504CysAsp: 0.504 ± 0.011	0.562CysGlu: 0.562 ± 0.011	0.437CysPhe: 0.437 ± 0.011	0.812CysGly: 0.812 ± 0.018	0.256CysHis: 0.256 ± 0.009	0.585CysIle: 0.585 ± 0.014	0.454CysLys: 0.454 ± 0.011	1.076CysLeu: 1.076 ± 0.017	0.214CysMet: 0.214 ± 0.007	0.329CysAsn: 0.329 ± 0.009	0.562CysPro: 0.562 ± 0.013	0.389CysGln: 0.389 ± 0.01	0.53CysArg: 0.53 ± 0.013	0.757CysSer: 0.757 ± 0.015	0.593CysThr: 0.593 ± 0.013	0.636CysVal: 0.636 ± 0.012	0.176CysTrp: 0.176 ± 0.007	0.306CysTyr: 0.306 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	3.577AspAla: 3.577 ± 0.034	0.523AspCys: 0.523 ± 0.012	4.221AspAsp: 4.221 ± 0.045	5.257AspGlu: 5.257 ± 0.052	1.793AspPhe: 1.793 ± 0.022	4.122AspGly: 4.122 ± 0.035	1.328AspHis: 1.328 ± 0.02	2.939AspIle: 2.939 ± 0.026	2.658AspLys: 2.658 ± 0.027	5.161AspLeu: 5.161 ± 0.034	1.179AspMet: 1.179 ± 0.017	1.805AspAsn: 1.805 ± 0.022	3.376AspPro: 3.376 ± 0.025	2.211AspGln: 2.211 ± 0.024	2.98AspArg: 2.98 ± 0.035	3.825AspSer: 3.825 ± 0.035	2.877AspThr: 2.877 ± 0.029	3.455AspVal: 3.455 ± 0.033	0.899AspTrp: 0.899 ± 0.015	1.431AspTyr: 1.431 ± 0.023	0.0AspXaa: 0.0 ± 0.0
Glu	4.492GluAla: 4.492 ± 0.039	0.568GluCys: 0.568 ± 0.013	4.858GluAsp: 4.858 ± 0.049	7.249GluGlu: 7.249 ± 0.076	1.725GluPhe: 1.725 ± 0.022	5.184GluGly: 5.184 ± 0.038	1.264GluHis: 1.264 ± 0.017	3.323GluIle: 3.323 ± 0.028	4.244GluLys: 4.244 ± 0.037	5.113GluLeu: 5.113 ± 0.046	1.654GluMet: 1.654 ± 0.02	2.341GluAsn: 2.341 ± 0.024	2.516GluPro: 2.516 ± 0.025	2.348GluGln: 2.348 ± 0.024	4.287GluArg: 4.287 ± 0.041	4.362GluSer: 4.362 ± 0.033	2.967GluThr: 2.967 ± 0.026	4.115GluVal: 4.115 ± 0.042	0.975GluTrp: 0.975 ± 0.017	1.705GluTyr: 1.705 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	2.607PheAla: 2.607 ± 0.028	0.437PheCys: 0.437 ± 0.011	2.113PheAsp: 2.113 ± 0.023	1.914PheGlu: 1.914 ± 0.023	1.371PhePhe: 1.371 ± 0.022	2.755PheGly: 2.755 ± 0.037	0.793PheHis: 0.793 ± 0.016	1.695PheIle: 1.695 ± 0.022	1.508PheLys: 1.508 ± 0.021	3.032PheLeu: 3.032 ± 0.035	0.679PheMet: 0.679 ± 0.013	1.354PheAsn: 1.354 ± 0.019	1.873PhePro: 1.873 ± 0.022	1.15PheGln: 1.15 ± 0.017	1.667PheArg: 1.667 ± 0.02	2.802PheSer: 2.802 ± 0.027	2.084PheThr: 2.084 ± 0.022	2.035PheVal: 2.035 ± 0.021	0.543PheTrp: 0.543 ± 0.011	0.936PheTyr: 0.936 ± 0.019	0.0PheXaa: 0.0 ± 0.0
Gly	4.52GlyAla: 4.52 ± 0.041	0.792GlyCys: 0.792 ± 0.016	3.744GlyAsp: 3.744 ± 0.032	4.68GlyGlu: 4.68 ± 0.035	2.541GlyPhe: 2.541 ± 0.027	7.076GlyGly: 7.076 ± 0.084	1.596GlyHis: 1.596 ± 0.022	3.628GlyIle: 3.628 ± 0.031	4.347GlyLys: 4.347 ± 0.039	6.369GlyLeu: 6.369 ± 0.047	1.913GlyMet: 1.913 ± 0.027	2.758GlyAsn: 2.758 ± 0.032	3.284GlyPro: 3.284 ± 0.033	2.753GlyGln: 2.753 ± 0.035	4.205GlyArg: 4.205 ± 0.037	6.339GlySer: 6.339 ± 0.056	3.9GlyThr: 3.9 ± 0.037	4.495GlyVal: 4.495 ± 0.035	1.39GlyTrp: 1.39 ± 0.022	2.253GlyTyr: 2.253 ± 0.026	0.0GlyXaa: 0.0 ± 0.0
His	1.524HisAla: 1.524 ± 0.019	0.243HisCys: 0.243 ± 0.007	1.162HisAsp: 1.162 ± 0.016	1.225HisGlu: 1.225 ± 0.017	0.808HisPhe: 0.808 ± 0.013	1.543HisGly: 1.543 ± 0.021	0.972HisHis: 0.972 ± 0.026	1.175HisIle: 1.175 ± 0.019	0.907HisLys: 0.907 ± 0.016	2.424HisLeu: 2.424 ± 0.027	0.398HisMet: 0.398 ± 0.01	0.82HisAsn: 0.82 ± 0.012	2.03HisPro: 2.03 ± 0.023	1.031HisGln: 1.031 ± 0.02	1.387HisArg: 1.387 ± 0.018	2.081HisSer: 2.081 ± 0.025	1.382HisThr: 1.382 ± 0.018	1.227HisVal: 1.227 ± 0.017	0.288HisTrp: 0.288 ± 0.008	0.621HisTyr: 0.621 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	3.887IleAla: 3.887 ± 0.033	0.658IleCys: 0.658 ± 0.013	2.976IleAsp: 2.976 ± 0.029	2.989IleGlu: 2.989 ± 0.032	1.816IlePhe: 1.816 ± 0.023	3.375IleGly: 3.375 ± 0.032	1.264IleHis: 1.264 ± 0.017	2.723IleIle: 2.723 ± 0.03	2.548IleLys: 2.548 ± 0.027	4.568IleLeu: 4.568 ± 0.042	0.982IleMet: 0.982 ± 0.016	1.982IleAsn: 1.982 ± 0.024	3.925IlePro: 3.925 ± 0.035	1.893IleGln: 1.893 ± 0.022	2.839IleArg: 2.839 ± 0.025	4.591IleSer: 4.591 ± 0.035	3.097IleThr: 3.097 ± 0.028	2.981IleVal: 2.981 ± 0.034	0.737IleTrp: 0.737 ± 0.015	1.357IleTyr: 1.357 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.242LysAla: 4.242 ± 0.04	0.436LysCys: 0.436 ± 0.01	3.087LysAsp: 3.087 ± 0.028	4.109LysGlu: 4.109 ± 0.037	1.354LysPhe: 1.354 ± 0.019	3.916LysGly: 3.916 ± 0.035	1.076LysHis: 1.076 ± 0.017	2.54LysIle: 2.54 ± 0.028	3.989LysLys: 3.989 ± 0.051	4.118LysLeu: 4.118 ± 0.031	1.116LysMet: 1.116 ± 0.017	1.779LysAsn: 1.779 ± 0.022	2.947LysPro: 2.947 ± 0.036	1.754LysGln: 1.754 ± 0.023	3.72LysArg: 3.72 ± 0.037	4.148LysSer: 4.148 ± 0.038	2.772LysThr: 2.772 ± 0.026	3.228LysVal: 3.228 ± 0.03	0.725LysTrp: 0.725 ± 0.014	1.344LysTyr: 1.344 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	6.861LeuAla: 6.861 ± 0.049	0.969LeuCys: 0.969 ± 0.015	4.982LeuAsp: 4.982 ± 0.036	5.325LeuGlu: 5.325 ± 0.043	3.085LeuPhe: 3.085 ± 0.034	6.049LeuGly: 6.049 ± 0.04	2.082LeuHis: 2.082 ± 0.024	4.341LeuIle: 4.341 ± 0.04	4.454LeuLys: 4.454 ± 0.037	8.167LeuLeu: 8.167 ± 0.067	1.647LeuMet: 1.647 ± 0.02	3.401LeuAsn: 3.401 ± 0.026	6.497LeuPro: 6.497 ± 0.04	3.184LeuGln: 3.184 ± 0.032	5.028LeuArg: 5.028 ± 0.043	8.308LeuSer: 8.308 ± 0.053	5.085LeuThr: 5.085 ± 0.038	4.972LeuVal: 4.972 ± 0.04	1.03LeuTrp: 1.03 ± 0.016	2.17LeuTyr: 2.17 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	1.653MetAla: 1.653 ± 0.021	0.188MetCys: 0.188 ± 0.007	1.245MetAsp: 1.245 ± 0.015	1.256MetGlu: 1.256 ± 0.016	0.68MetPhe: 0.68 ± 0.014	1.646MetGly: 1.646 ± 0.022	0.329MetHis: 0.329 ± 0.009	1.117MetIle: 1.117 ± 0.017	1.062MetLys: 1.062 ± 0.016	1.596MetLeu: 1.596 ± 0.021	0.611MetMet: 0.611 ± 0.015	0.826MetAsn: 0.826 ± 0.013	1.161MetPro: 1.161 ± 0.017	0.67MetGln: 0.67 ± 0.014	1.206MetArg: 1.206 ± 0.015	2.165MetSer: 2.165 ± 0.024	1.357MetThr: 1.357 ± 0.019	1.226MetVal: 1.226 ± 0.017	0.231MetTrp: 0.231 ± 0.008	0.491MetTyr: 0.491 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.854AsnAla: 2.854 ± 0.026	0.343AsnCys: 0.343 ± 0.009	2.149AsnAsp: 2.149 ± 0.024	2.256AsnGlu: 2.256 ± 0.025	1.198AsnPhe: 1.198 ± 0.017	3.395AsnGly: 3.395 ± 0.033	0.922AsnHis: 0.922 ± 0.016	1.912AsnIle: 1.912 ± 0.021	1.739AsnLys: 1.739 ± 0.021	3.4AsnLeu: 3.4 ± 0.029	0.712AsnMet: 0.712 ± 0.014	1.609AsnAsn: 1.609 ± 0.024	2.683AsnPro: 2.683 ± 0.027	1.55AsnGln: 1.55 ± 0.023	1.958AsnArg: 1.958 ± 0.022	3.026AsnSer: 3.026 ± 0.034	2.427AsnThr: 2.427 ± 0.026	2.225AsnVal: 2.225 ± 0.024	0.492AsnTrp: 0.492 ± 0.012	0.96AsnTyr: 0.96 ± 0.016	0.0AsnXaa: 0.0 ± 0.0
Pro	4.716ProAla: 4.716 ± 0.05	0.41ProCys: 0.41 ± 0.011	2.924ProAsp: 2.924 ± 0.026	3.553ProGlu: 3.553 ± 0.029	2.126ProPhe: 2.126 ± 0.024	3.59ProGly: 3.59 ± 0.037	1.582ProHis: 1.582 ± 0.026	3.416ProIle: 3.416 ± 0.03	2.909ProLys: 2.909 ± 0.034	5.464ProLeu: 5.464 ± 0.037	1.0ProMet: 1.0 ± 0.017	2.576ProAsn: 2.576 ± 0.029	6.932ProPro: 6.932 ± 0.084	2.63ProGln: 2.63 ± 0.033	3.261ProArg: 3.261 ± 0.03	8.811ProSer: 8.811 ± 0.069	5.218ProThr: 5.218 ± 0.048	3.359ProVal: 3.359 ± 0.033	0.623ProTrp: 0.623 ± 0.012	1.587ProTyr: 1.587 ± 0.023	0.0ProXaa: 0.0 ± 0.0
Gln	3.31GlnAla: 3.31 ± 0.033	0.373GlnCys: 0.373 ± 0.01	1.963GlnAsp: 1.963 ± 0.022	2.264GlnGlu: 2.264 ± 0.026	1.084GlnPhe: 1.084 ± 0.015	2.554GlnGly: 2.554 ± 0.028	0.975GlnHis: 0.975 ± 0.017	1.918GlnIle: 1.918 ± 0.022	1.718GlnLys: 1.718 ± 0.02	3.184GlnLeu: 3.184 ± 0.032	0.85GlnMet: 0.85 ± 0.017	1.578GlnAsn: 1.578 ± 0.021	2.924GlnPro: 2.924 ± 0.034	2.432GlnGln: 2.432 ± 0.068	2.272GlnArg: 2.272 ± 0.025	3.463GlnSer: 3.463 ± 0.032	2.26GlnThr: 2.26 ± 0.027	2.165GlnVal: 2.165 ± 0.024	0.493GlnTrp: 0.493 ± 0.011	1.046GlnTyr: 1.046 ± 0.019	0.0GlnXaa: 0.0 ± 0.0
Arg	3.966ArgAla: 3.966 ± 0.035	0.563ArgCys: 0.563 ± 0.014	3.196ArgAsp: 3.196 ± 0.033	4.03ArgGlu: 4.03 ± 0.037	1.883ArgPhe: 1.883 ± 0.022	3.784ArgGly: 3.784 ± 0.035	1.296ArgHis: 1.296 ± 0.017	2.802ArgIle: 2.802 ± 0.024	3.641ArgLys: 3.641 ± 0.034	4.93ArgLeu: 4.93 ± 0.041	1.303ArgMet: 1.303 ± 0.016	2.092ArgAsn: 2.092 ± 0.024	3.501ArgPro: 3.501 ± 0.033	2.288ArgGln: 2.288 ± 0.025	4.815ArgArg: 4.815 ± 0.048	5.259ArgSer: 5.259 ± 0.051	3.062ArgThr: 3.062 ± 0.03	3.024ArgVal: 3.024 ± 0.029	0.859ArgTrp: 0.859 ± 0.014	1.621ArgTyr: 1.621 ± 0.023	0.0ArgXaa: 0.0 ± 0.0
Ser	6.908SerAla: 6.908 ± 0.051	0.739SerCys: 0.739 ± 0.015	4.378SerAsp: 4.378 ± 0.035	4.511SerGlu: 4.511 ± 0.032	3.051SerPhe: 3.051 ± 0.032	6.158SerGly: 6.158 ± 0.046	2.22SerHis: 2.22 ± 0.026	4.676SerIle: 4.676 ± 0.036	4.351SerLys: 4.351 ± 0.036	7.925SerLeu: 7.925 ± 0.053	1.667SerMet: 1.667 ± 0.023	3.722SerAsn: 3.722 ± 0.035	6.997SerPro: 6.997 ± 0.075	3.535SerGln: 3.535 ± 0.031	5.168SerArg: 5.168 ± 0.05	13.072SerSer: 13.072 ± 0.115	7.616SerThr: 7.616 ± 0.069	4.448SerVal: 4.448 ± 0.031	1.061SerTrp: 1.061 ± 0.017	2.216SerTyr: 2.216 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	4.581ThrAla: 4.581 ± 0.038	0.631ThrCys: 0.631 ± 0.012	2.683ThrAsp: 2.683 ± 0.028	2.89ThrGlu: 2.89 ± 0.026	2.224ThrPhe: 2.224 ± 0.025	4.036ThrGly: 4.036 ± 0.034	1.46ThrHis: 1.46 ± 0.021	3.291ThrIle: 3.291 ± 0.031	2.732ThrLys: 2.732 ± 0.025	5.395ThrLeu: 5.395 ± 0.041	1.01ThrMet: 1.01 ± 0.014	2.324ThrAsn: 2.324 ± 0.026	5.423ThrPro: 5.423 ± 0.051	2.173ThrGln: 2.173 ± 0.025	2.963ThrArg: 2.963 ± 0.025	7.075ThrSer: 7.075 ± 0.067	4.463ThrThr: 4.463 ± 0.05	3.251ThrVal: 3.251 ± 0.031	0.747ThrTrp: 0.747 ± 0.016	1.664ThrTyr: 1.664 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	4.045ValAla: 4.045 ± 0.033	0.644ValCys: 0.644 ± 0.014	3.652ValAsp: 3.652 ± 0.028	4.167ValGlu: 4.167 ± 0.047	2.02ValPhe: 2.02 ± 0.026	4.212ValGly: 4.212 ± 0.032	1.27ValHis: 1.27 ± 0.018	3.08ValIle: 3.08 ± 0.032	3.189ValLys: 3.189 ± 0.034	5.121ValLeu: 5.121 ± 0.044	1.22ValMet: 1.22 ± 0.016	2.251ValAsn: 2.251 ± 0.024	3.529ValPro: 3.529 ± 0.033	2.15ValGln: 2.15 ± 0.022	3.129ValArg: 3.129 ± 0.031	4.35ValSer: 4.35 ± 0.037	3.008ValThr: 3.008 ± 0.032	3.899ValVal: 3.899 ± 0.036	0.838ValTrp: 0.838 ± 0.015	1.546ValTyr: 1.546 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	0.913TrpAla: 0.913 ± 0.017	0.181TrpCys: 0.181 ± 0.006	0.886TrpAsp: 0.886 ± 0.015	0.932TrpGlu: 0.932 ± 0.017	0.486TrpPhe: 0.486 ± 0.011	0.964TrpGly: 0.964 ± 0.017	0.274TrpHis: 0.274 ± 0.008	0.722TrpIle: 0.722 ± 0.014	0.86TrpLys: 0.86 ± 0.015	1.208TrpLeu: 1.208 ± 0.019	0.364TrpMet: 0.364 ± 0.009	0.608TrpAsn: 0.608 ± 0.012	0.509TrpPro: 0.509 ± 0.011	0.461TrpGln: 0.461 ± 0.011	0.888TrpArg: 0.888 ± 0.017	1.102TrpSer: 1.102 ± 0.018	0.844TrpThr: 0.844 ± 0.016	0.848TrpVal: 0.848 ± 0.014	0.308TrpTrp: 0.308 ± 0.009	0.414TrpTyr: 0.414 ± 0.01	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.894TyrAla: 1.894 ± 0.025	0.346TyrCys: 0.346 ± 0.01	1.636TyrAsp: 1.636 ± 0.023	1.503TyrGlu: 1.503 ± 0.021	1.037TyrPhe: 1.037 ± 0.017	2.013TyrGly: 2.013 ± 0.021	0.758TyrHis: 0.758 ± 0.014	1.365TyrIle: 1.365 ± 0.019	1.171TyrLys: 1.171 ± 0.016	2.526TyrLeu: 2.526 ± 0.029	0.537TyrMet: 0.537 ± 0.011	1.078TyrAsn: 1.078 ± 0.015	1.605TyrPro: 1.605 ± 0.023	1.076TyrGln: 1.076 ± 0.017	1.451TyrArg: 1.451 ± 0.019	2.021TyrSer: 2.021 ± 0.027	1.696TyrThr: 1.696 ± 0.021	1.454TyrVal: 1.454 ± 0.019	0.384TyrTrp: 0.384 ± 0.009	0.798TyrTyr: 0.798 ± 0.014	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9131 proteins (4442483 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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