Amino acid dipepetide frequency for Symphysodon discus adomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.847AlaAla: 3.847 ± 0.813
1.731AlaCys: 1.731 ± 0.521
2.885AlaAsp: 2.885 ± 0.741
3.847AlaGlu: 3.847 ± 1.089
2.5AlaPhe: 2.5 ± 0.785
3.27AlaGly: 3.27 ± 0.849
2.116AlaHis: 2.116 ± 0.649
3.078AlaIle: 3.078 ± 0.776
3.27AlaLys: 3.27 ± 0.755
6.347AlaLeu: 6.347 ± 0.771
1.539AlaMet: 1.539 ± 0.584
2.308AlaAsn: 2.308 ± 0.524
5.77AlaPro: 5.77 ± 1.452
4.616AlaGln: 4.616 ± 0.929
4.424AlaArg: 4.424 ± 1.609
6.347AlaSer: 6.347 ± 0.785
2.693AlaThr: 2.693 ± 0.765
6.347AlaVal: 6.347 ± 1.062
0.769AlaTrp: 0.769 ± 0.535
1.346AlaTyr: 1.346 ± 0.318
0.0AlaXaa: 0.0 ± 0.0
Cys
3.462CysAla: 3.462 ± 0.664
1.154CysCys: 1.154 ± 0.545
0.962CysAsp: 0.962 ± 0.324
2.885CysGlu: 2.885 ± 0.551
1.346CysPhe: 1.346 ± 0.484
1.539CysGly: 1.539 ± 0.586
1.154CysHis: 1.154 ± 0.377
0.192CysIle: 0.192 ± 0.171
1.731CysLys: 1.731 ± 0.486
1.923CysLeu: 1.923 ± 0.547
0.385CysMet: 0.385 ± 0.259
1.539CysAsn: 1.539 ± 0.786
0.577CysPro: 0.577 ± 0.36
0.962CysGln: 0.962 ± 0.483
0.962CysArg: 0.962 ± 0.179
1.923CysSer: 1.923 ± 0.66
1.539CysThr: 1.539 ± 0.716
2.308CysVal: 2.308 ± 0.841
0.192CysTrp: 0.192 ± 0.208
0.192CysTyr: 0.192 ± 0.161
0.0CysXaa: 0.0 ± 0.0
Asp
2.116AspAla: 2.116 ± 0.463
0.962AspCys: 0.962 ± 0.4
2.693AspAsp: 2.693 ± 0.709
3.27AspGlu: 3.27 ± 0.818
1.923AspPhe: 1.923 ± 0.626
1.154AspGly: 1.154 ± 0.359
0.577AspHis: 0.577 ± 0.273
3.27AspIle: 3.27 ± 0.822
0.962AspLys: 0.962 ± 0.527
5.193AspLeu: 5.193 ± 1.359
2.116AspMet: 2.116 ± 0.763
1.539AspAsn: 1.539 ± 0.512
1.731AspPro: 1.731 ± 0.506
1.539AspGln: 1.539 ± 0.384
2.5AspArg: 2.5 ± 0.583
5.386AspSer: 5.386 ± 1.459
3.462AspThr: 3.462 ± 1.002
3.078AspVal: 3.078 ± 0.509
0.0AspTrp: 0.0 ± 0.0
0.769AspTyr: 0.769 ± 0.364
0.0AspXaa: 0.0 ± 0.0
Glu
3.462GluAla: 3.462 ± 0.929
1.731GluCys: 1.731 ± 0.682
2.5GluAsp: 2.5 ± 0.771
4.616GluGlu: 4.616 ± 1.483
1.539GluPhe: 1.539 ± 0.69
2.308GluGly: 2.308 ± 0.669
3.078GluHis: 3.078 ± 0.819
2.693GluIle: 2.693 ± 0.738
2.116GluLys: 2.116 ± 0.443
3.462GluLeu: 3.462 ± 0.526
1.539GluMet: 1.539 ± 0.325
2.693GluAsn: 2.693 ± 0.612
6.54GluPro: 6.54 ± 2.225
3.462GluGln: 3.462 ± 0.754
3.655GluArg: 3.655 ± 0.665
4.809GluSer: 4.809 ± 0.974
4.232GluThr: 4.232 ± 1.01
2.885GluVal: 2.885 ± 0.698
0.577GluTrp: 0.577 ± 0.204
1.539GluTyr: 1.539 ± 0.43
0.0GluXaa: 0.0 ± 0.0
Phe
1.923PheAla: 1.923 ± 0.593
1.346PheCys: 1.346 ± 0.651
1.539PheAsp: 1.539 ± 0.546
2.116PheGlu: 2.116 ± 0.587
1.539PhePhe: 1.539 ± 0.574
1.731PheGly: 1.731 ± 0.335
0.192PheHis: 0.192 ± 0.185
0.962PheIle: 0.962 ± 0.535
1.346PheLys: 1.346 ± 0.528
4.039PheLeu: 4.039 ± 0.883
0.577PheMet: 0.577 ± 0.21
2.308PheAsn: 2.308 ± 0.88
1.731PhePro: 1.731 ± 0.389
0.385PheGln: 0.385 ± 0.343
1.539PheArg: 1.539 ± 0.467
3.462PheSer: 3.462 ± 0.728
3.462PheThr: 3.462 ± 0.822
4.424PheVal: 4.424 ± 0.556
0.385PheTrp: 0.385 ± 0.211
1.154PheTyr: 1.154 ± 0.335
0.0PheXaa: 0.0 ± 0.0
Gly
3.462GlyAla: 3.462 ± 1.209
1.539GlyCys: 1.539 ± 0.434
2.885GlyAsp: 2.885 ± 0.486
2.116GlyGlu: 2.116 ± 0.748
1.346GlyPhe: 1.346 ± 0.469
5.001GlyGly: 5.001 ± 1.567
2.116GlyHis: 2.116 ± 0.351
2.308GlyIle: 2.308 ± 0.538
2.5GlyLys: 2.5 ± 0.615
5.001GlyLeu: 5.001 ± 0.776
1.346GlyMet: 1.346 ± 0.43
2.885GlyAsn: 2.885 ± 1.163
4.039GlyPro: 4.039 ± 0.859
3.078GlyGln: 3.078 ± 0.617
4.039GlyArg: 4.039 ± 0.985
4.232GlySer: 4.232 ± 0.989
3.462GlyThr: 3.462 ± 0.847
3.462GlyVal: 3.462 ± 0.742
0.577GlyTrp: 0.577 ± 0.27
1.539GlyTyr: 1.539 ± 0.571
0.0GlyXaa: 0.0 ± 0.0
His
2.5HisAla: 2.5 ± 0.942
0.192HisCys: 0.192 ± 0.161
1.731HisAsp: 1.731 ± 0.386
1.923HisGlu: 1.923 ± 0.547
0.962HisPhe: 0.962 ± 0.252
3.078HisGly: 3.078 ± 0.515
1.154HisHis: 1.154 ± 0.672
0.962HisIle: 0.962 ± 0.259
1.539HisLys: 1.539 ± 0.532
1.731HisLeu: 1.731 ± 0.408
1.731HisMet: 1.731 ± 0.544
1.731HisAsn: 1.731 ± 0.45
0.962HisPro: 0.962 ± 0.477
1.154HisGln: 1.154 ± 0.333
1.731HisArg: 1.731 ± 0.539
3.847HisSer: 3.847 ± 0.723
3.847HisThr: 3.847 ± 1.187
2.885HisVal: 2.885 ± 0.745
0.192HisTrp: 0.192 ± 0.205
0.962HisTyr: 0.962 ± 0.515
0.0HisXaa: 0.0 ± 0.0
Ile
1.923IleAla: 1.923 ± 0.581
0.769IleCys: 0.769 ± 0.359
1.346IleAsp: 1.346 ± 0.683
1.154IleGlu: 1.154 ± 0.479
0.769IlePhe: 0.769 ± 0.228
2.308IleGly: 2.308 ± 0.634
0.577IleHis: 0.577 ± 0.272
1.154IleIle: 1.154 ± 0.496
1.539IleLys: 1.539 ± 0.386
4.039IleLeu: 4.039 ± 0.755
1.346IleMet: 1.346 ± 0.412
1.731IleAsn: 1.731 ± 0.41
5.001IlePro: 5.001 ± 0.761
1.923IleGln: 1.923 ± 0.547
2.693IleArg: 2.693 ± 0.616
3.655IleSer: 3.655 ± 0.868
3.847IleThr: 3.847 ± 1.009
2.693IleVal: 2.693 ± 0.985
0.0IleTrp: 0.0 ± 0.0
1.731IleTyr: 1.731 ± 0.556
0.0IleXaa: 0.0 ± 0.0
Lys
2.116LysAla: 2.116 ± 0.747
1.154LysCys: 1.154 ± 0.376
1.731LysAsp: 1.731 ± 0.566
1.923LysGlu: 1.923 ± 0.692
0.962LysPhe: 0.962 ± 0.289
2.308LysGly: 2.308 ± 0.708
3.655LysHis: 3.655 ± 0.805
1.923LysIle: 1.923 ± 0.4
4.809LysLys: 4.809 ± 1.058
4.616LysLeu: 4.616 ± 0.75
0.385LysMet: 0.385 ± 0.257
2.5LysAsn: 2.5 ± 0.467
3.078LysPro: 3.078 ± 0.753
1.346LysGln: 1.346 ± 0.557
4.232LysArg: 4.232 ± 0.859
2.885LysSer: 2.885 ± 0.839
3.078LysThr: 3.078 ± 0.586
2.308LysVal: 2.308 ± 0.695
0.192LysTrp: 0.192 ± 0.161
1.346LysTyr: 1.346 ± 0.439
0.0LysXaa: 0.0 ± 0.0
Leu
7.117LeuAla: 7.117 ± 1.504
2.116LeuCys: 2.116 ± 0.57
2.693LeuAsp: 2.693 ± 0.484
4.424LeuGlu: 4.424 ± 1.059
3.462LeuPhe: 3.462 ± 0.592
5.578LeuGly: 5.578 ± 1.543
2.5LeuHis: 2.5 ± 0.438
3.655LeuIle: 3.655 ± 0.781
3.655LeuLys: 3.655 ± 0.851
7.117LeuLeu: 7.117 ± 0.883
1.731LeuMet: 1.731 ± 0.477
3.655LeuAsn: 3.655 ± 0.917
4.039LeuPro: 4.039 ± 0.657
4.232LeuGln: 4.232 ± 0.981
5.963LeuArg: 5.963 ± 1.028
4.809LeuSer: 4.809 ± 0.782
6.54LeuThr: 6.54 ± 1.022
5.001LeuVal: 5.001 ± 0.811
0.192LeuTrp: 0.192 ± 0.173
2.5LeuTyr: 2.5 ± 0.697
0.192LeuXaa: 0.192 ± 0.185
Met
1.539MetAla: 1.539 ± 0.775
1.731MetCys: 1.731 ± 0.59
0.769MetAsp: 0.769 ± 0.294
0.962MetGlu: 0.962 ± 0.378
1.539MetPhe: 1.539 ± 0.575
0.577MetGly: 0.577 ± 0.376
0.769MetHis: 0.769 ± 0.271
0.962MetIle: 0.962 ± 0.255
0.577MetLys: 0.577 ± 0.386
3.27MetLeu: 3.27 ± 0.579
0.385MetMet: 0.385 ± 0.234
0.385MetAsn: 0.385 ± 0.209
2.5MetPro: 2.5 ± 0.602
1.346MetGln: 1.346 ± 0.5
2.116MetArg: 2.116 ± 0.755
1.923MetSer: 1.923 ± 0.478
1.539MetThr: 1.539 ± 0.442
1.346MetVal: 1.346 ± 0.383
0.192MetTrp: 0.192 ± 0.17
0.577MetTyr: 0.577 ± 0.518
0.0MetXaa: 0.0 ± 0.0
Asn
2.885AsnAla: 2.885 ± 0.657
2.116AsnCys: 2.116 ± 0.585
2.308AsnAsp: 2.308 ± 0.54
2.308AsnGlu: 2.308 ± 0.609
0.385AsnPhe: 0.385 ± 0.246
2.885AsnGly: 2.885 ± 0.65
2.116AsnHis: 2.116 ± 0.485
2.116AsnIle: 2.116 ± 0.389
1.154AsnLys: 1.154 ± 0.497
3.078AsnLeu: 3.078 ± 0.272
0.962AsnMet: 0.962 ± 0.46
1.923AsnAsn: 1.923 ± 0.504
2.116AsnPro: 2.116 ± 0.682
0.962AsnGln: 0.962 ± 0.437
2.693AsnArg: 2.693 ± 0.815
2.5AsnSer: 2.5 ± 0.854
4.424AsnThr: 4.424 ± 0.828
2.5AsnVal: 2.5 ± 0.59
0.769AsnTrp: 0.769 ± 0.352
1.346AsnTyr: 1.346 ± 0.516
0.0AsnXaa: 0.0 ± 0.0
Pro
5.578ProAla: 5.578 ± 1.25
1.731ProCys: 1.731 ± 0.359
2.885ProAsp: 2.885 ± 0.854
5.77ProGlu: 5.77 ± 2.268
1.923ProPhe: 1.923 ± 0.572
5.386ProGly: 5.386 ± 0.805
1.539ProHis: 1.539 ± 0.46
4.232ProIle: 4.232 ± 0.902
2.693ProLys: 2.693 ± 1.026
4.809ProLeu: 4.809 ± 1.091
0.192ProMet: 0.192 ± 0.161
2.693ProAsn: 2.693 ± 0.682
6.54ProPro: 6.54 ± 2.714
3.462ProGln: 3.462 ± 1.135
2.885ProArg: 2.885 ± 0.381
5.386ProSer: 5.386 ± 1.103
2.885ProThr: 2.885 ± 0.695
5.001ProVal: 5.001 ± 1.14
0.0ProTrp: 0.0 ± 0.0
2.693ProTyr: 2.693 ± 0.729
0.0ProXaa: 0.0 ± 0.0
Gln
4.039GlnAla: 4.039 ± 0.665
0.769GlnCys: 0.769 ± 0.413
2.308GlnAsp: 2.308 ± 0.683
3.655GlnGlu: 3.655 ± 0.911
1.346GlnPhe: 1.346 ± 0.772
2.308GlnGly: 2.308 ± 0.601
2.5GlnHis: 2.5 ± 0.671
0.962GlnIle: 0.962 ± 0.517
2.308GlnLys: 2.308 ± 0.717
2.885GlnLeu: 2.885 ± 0.875
1.539GlnMet: 1.539 ± 0.645
2.116GlnAsn: 2.116 ± 0.486
3.078GlnPro: 3.078 ± 0.677
3.078GlnGln: 3.078 ± 1.13
3.655GlnArg: 3.655 ± 0.72
2.116GlnSer: 2.116 ± 0.718
2.693GlnThr: 2.693 ± 0.505
4.232GlnVal: 4.232 ± 1.133
0.0GlnTrp: 0.0 ± 0.0
0.769GlnTyr: 0.769 ± 0.542
0.0GlnXaa: 0.0 ± 0.0
Arg
5.386ArgAla: 5.386 ± 1.097
0.769ArgCys: 0.769 ± 0.451
3.078ArgAsp: 3.078 ± 0.769
4.039ArgGlu: 4.039 ± 0.849
1.923ArgPhe: 1.923 ± 0.528
4.232ArgGly: 4.232 ± 1.295
1.923ArgHis: 1.923 ± 0.375
2.308ArgIle: 2.308 ± 0.585
4.424ArgLys: 4.424 ± 0.876
3.655ArgLeu: 3.655 ± 1.015
2.116ArgMet: 2.116 ± 0.595
2.693ArgAsn: 2.693 ± 0.618
3.078ArgPro: 3.078 ± 0.478
2.116ArgGln: 2.116 ± 0.435
4.232ArgArg: 4.232 ± 0.718
5.578ArgSer: 5.578 ± 1.571
4.232ArgThr: 4.232 ± 0.541
4.039ArgVal: 4.039 ± 0.795
1.346ArgTrp: 1.346 ± 0.374
1.923ArgTyr: 1.923 ± 0.502
0.0ArgXaa: 0.0 ± 0.0
Ser
7.309SerAla: 7.309 ± 0.73
0.962SerCys: 0.962 ± 0.316
5.386SerAsp: 5.386 ± 1.532
4.039SerGlu: 4.039 ± 0.838
2.885SerPhe: 2.885 ± 0.647
4.616SerGly: 4.616 ± 0.876
2.116SerHis: 2.116 ± 0.712
1.923SerIle: 1.923 ± 0.595
3.078SerLys: 3.078 ± 0.708
5.578SerLeu: 5.578 ± 0.925
1.539SerMet: 1.539 ± 0.441
2.693SerAsn: 2.693 ± 0.823
6.155SerPro: 6.155 ± 0.995
3.847SerGln: 3.847 ± 0.83
3.847SerArg: 3.847 ± 0.686
8.463SerSer: 8.463 ± 1.947
6.347SerThr: 6.347 ± 0.73
7.117SerVal: 7.117 ± 1.091
0.962SerTrp: 0.962 ± 0.292
2.693SerTyr: 2.693 ± 0.471
0.0SerXaa: 0.0 ± 0.0
Thr
3.847ThrAla: 3.847 ± 0.759
1.923ThrCys: 1.923 ± 0.938
3.462ThrAsp: 3.462 ± 0.847
5.193ThrGlu: 5.193 ± 1.259
4.039ThrPhe: 4.039 ± 1.126
5.193ThrGly: 5.193 ± 0.565
2.885ThrHis: 2.885 ± 0.655
1.731ThrIle: 1.731 ± 0.424
3.655ThrLys: 3.655 ± 0.693
5.77ThrLeu: 5.77 ± 1.114
2.308ThrMet: 2.308 ± 0.701
1.731ThrAsn: 1.731 ± 0.526
4.616ThrPro: 4.616 ± 1.062
3.462ThrGln: 3.462 ± 0.646
5.001ThrArg: 5.001 ± 0.852
4.809ThrSer: 4.809 ± 0.648
4.039ThrThr: 4.039 ± 0.731
4.039ThrVal: 4.039 ± 1.067
0.962ThrTrp: 0.962 ± 0.29
2.116ThrTyr: 2.116 ± 0.401
0.0ThrXaa: 0.0 ± 0.0
Val
3.847ValAla: 3.847 ± 0.956
1.539ValCys: 1.539 ± 0.623
1.539ValAsp: 1.539 ± 0.335
3.655ValGlu: 3.655 ± 0.933
3.078ValPhe: 3.078 ± 0.728
1.923ValGly: 1.923 ± 0.234
2.885ValHis: 2.885 ± 0.679
3.847ValIle: 3.847 ± 0.923
3.847ValLys: 3.847 ± 0.769
6.155ValLeu: 6.155 ± 1.093
1.923ValMet: 1.923 ± 0.837
2.693ValAsn: 2.693 ± 0.533
4.616ValPro: 4.616 ± 0.878
4.616ValGln: 4.616 ± 1.076
4.616ValArg: 4.616 ± 0.905
7.886ValSer: 7.886 ± 1.049
7.117ValThr: 7.117 ± 1.351
5.386ValVal: 5.386 ± 0.964
0.0ValTrp: 0.0 ± 0.0
1.346ValTyr: 1.346 ± 0.321
0.0ValXaa: 0.0 ± 0.0
Trp
0.577TrpAla: 0.577 ± 0.195
0.769TrpCys: 0.769 ± 0.308
0.769TrpAsp: 0.769 ± 0.423
0.385TrpGlu: 0.385 ± 0.346
0.0TrpPhe: 0.0 ± 0.0
0.192TrpGly: 0.192 ± 0.161
0.0TrpHis: 0.0 ± 0.0
0.385TrpIle: 0.385 ± 0.237
0.192TrpLys: 0.192 ± 0.161
0.577TrpLeu: 0.577 ± 0.255
0.577TrpMet: 0.577 ± 0.279
0.192TrpAsn: 0.192 ± 0.185
0.769TrpPro: 0.769 ± 0.254
0.385TrpGln: 0.385 ± 0.343
0.769TrpArg: 0.769 ± 0.435
0.385TrpSer: 0.385 ± 0.22
0.0TrpThr: 0.0 ± 0.0
0.385TrpVal: 0.385 ± 0.246
0.0TrpTrp: 0.0 ± 0.0
0.192TrpTyr: 0.192 ± 0.171
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.116TyrAla: 2.116 ± 0.643
1.923TyrCys: 1.923 ± 0.731
0.769TyrAsp: 0.769 ± 0.383
1.154TyrGlu: 1.154 ± 0.659
2.693TyrPhe: 2.693 ± 0.767
1.346TyrGly: 1.346 ± 0.509
0.962TyrHis: 0.962 ± 0.272
1.539TyrIle: 1.539 ± 0.572
1.154TyrLys: 1.154 ± 0.572
1.731TyrLeu: 1.731 ± 0.487
0.577TyrMet: 0.577 ± 0.483
1.539TyrAsn: 1.539 ± 0.466
1.346TyrPro: 1.346 ± 0.458
0.385TyrGln: 0.385 ± 0.37
1.539TyrArg: 1.539 ± 0.549
1.154TyrSer: 1.154 ± 0.284
1.346TyrThr: 1.346 ± 0.532
3.27TyrVal: 3.27 ± 0.731
0.192TyrTrp: 0.192 ± 0.203
0.962TyrTyr: 0.962 ± 0.417
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.192XaaLeu: 0.192 ± 0.185
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 10 proteins (5200 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski