Amino acid dipepetide frequency for Phalaenopsis equestris amalgavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.096AlaAla: 11.096 ± 1.02
2.08AlaCys: 2.08 ± 0.277
4.854AlaAsp: 4.854 ± 1.559
7.628AlaGlu: 7.628 ± 2.841
2.08AlaPhe: 2.08 ± 1.093
6.241AlaGly: 6.241 ± 0.539
3.467AlaHis: 3.467 ± 0.452
0.693AlaIle: 0.693 ± 0.364
2.774AlaLys: 2.774 ± 1.457
10.402AlaLeu: 10.402 ± 2.754
2.774AlaMet: 2.774 ± 0.087
3.467AlaAsn: 3.467 ± 0.918
4.854AlaPro: 4.854 ± 1.559
1.387AlaGln: 1.387 ± 0.641
11.789AlaArg: 11.789 ± 2.025
4.854AlaSer: 4.854 ± 0.189
6.241AlaThr: 6.241 ± 0.83
5.548AlaVal: 5.548 ± 1.195
2.08AlaTrp: 2.08 ± 1.093
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
2.774CysAla: 2.774 ± 0.087
0.693CysCys: 0.693 ± 0.364
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
1.387CysPhe: 1.387 ± 0.728
1.387CysGly: 1.387 ± 0.728
0.0CysHis: 0.0 ± 0.0
0.693CysIle: 0.693 ± 0.364
0.693CysLys: 0.693 ± 0.364
1.387CysLeu: 1.387 ± 0.728
0.0CysMet: 0.0 ± 0.0
2.08CysAsn: 2.08 ± 0.277
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
1.387CysThr: 1.387 ± 0.641
1.387CysVal: 1.387 ± 0.728
1.387CysTrp: 1.387 ± 0.641
0.693CysTyr: 0.693 ± 0.364
0.0CysXaa: 0.0 ± 0.0
Asp
9.015AspAla: 9.015 ± 1.996
0.693AspCys: 0.693 ± 0.364
7.628AspAsp: 7.628 ± 1.267
6.241AspGlu: 6.241 ± 2.2
4.161AspPhe: 4.161 ± 0.816
4.854AspGly: 4.854 ± 0.189
0.693AspHis: 0.693 ± 0.364
1.387AspIle: 1.387 ± 0.728
0.0AspLys: 0.0 ± 0.0
5.548AspLeu: 5.548 ± 0.175
1.387AspMet: 1.387 ± 0.728
1.387AspAsn: 1.387 ± 0.728
2.08AspPro: 2.08 ± 1.646
0.693AspGln: 0.693 ± 1.005
1.387AspArg: 1.387 ± 0.641
1.387AspSer: 1.387 ± 0.728
3.467AspThr: 3.467 ± 0.918
3.467AspVal: 3.467 ± 0.918
2.774AspTrp: 2.774 ± 1.457
1.387AspTyr: 1.387 ± 0.728
0.0AspXaa: 0.0 ± 0.0
Glu
9.015GluAla: 9.015 ± 2.112
1.387GluCys: 1.387 ± 0.641
5.548GluAsp: 5.548 ± 0.175
4.161GluGlu: 4.161 ± 0.554
4.854GluPhe: 4.854 ± 1.559
4.161GluGly: 4.161 ± 0.554
0.0GluHis: 0.0 ± 0.0
2.774GluIle: 2.774 ± 0.087
4.161GluLys: 4.161 ± 0.554
4.854GluLeu: 4.854 ± 0.189
3.467GluMet: 3.467 ± 0.473
1.387GluAsn: 1.387 ± 0.641
4.161GluPro: 4.161 ± 1.923
2.774GluGln: 2.774 ± 0.087
3.467GluArg: 3.467 ± 1.821
4.854GluSer: 4.854 ± 0.189
4.161GluThr: 4.161 ± 3.292
2.08GluVal: 2.08 ± 1.646
1.387GluTrp: 1.387 ± 0.728
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
3.467PheAla: 3.467 ± 1.821
2.774PheCys: 2.774 ± 0.087
0.693PheAsp: 0.693 ± 0.364
2.774PheGlu: 2.774 ± 0.087
0.0PhePhe: 0.0 ± 0.0
3.467PheGly: 3.467 ± 0.452
0.693PheHis: 0.693 ± 0.364
3.467PheIle: 3.467 ± 0.918
0.693PheLys: 0.693 ± 0.364
2.774PheLeu: 2.774 ± 0.087
1.387PheMet: 1.387 ± 0.728
4.161PheAsn: 4.161 ± 0.554
2.774PhePro: 2.774 ± 0.087
2.774PheGln: 2.774 ± 0.087
4.854PheArg: 4.854 ± 0.189
3.467PheSer: 3.467 ± 0.452
0.0PheThr: 0.0 ± 0.0
2.08PheVal: 2.08 ± 1.093
0.0PheTrp: 0.0 ± 0.0
2.08PheTyr: 2.08 ± 0.277
0.0PheXaa: 0.0 ± 0.0
Gly
3.467GlyAla: 3.467 ± 0.918
0.0GlyCys: 0.0 ± 0.0
1.387GlyAsp: 1.387 ± 0.728
5.548GlyGlu: 5.548 ± 1.195
3.467GlyPhe: 3.467 ± 0.918
10.402GlyGly: 10.402 ± 0.015
0.0GlyHis: 0.0 ± 0.0
6.241GlyIle: 6.241 ± 1.908
2.08GlyLys: 2.08 ± 1.093
4.161GlyLeu: 4.161 ± 0.816
0.693GlyMet: 0.693 ± 0.364
3.467GlyAsn: 3.467 ± 0.452
3.467GlyPro: 3.467 ± 0.918
1.387GlyGln: 1.387 ± 0.641
3.467GlyArg: 3.467 ± 0.452
2.774GlySer: 2.774 ± 1.457
4.161GlyThr: 4.161 ± 0.554
4.161GlyVal: 4.161 ± 0.554
2.774GlyTrp: 2.774 ± 0.087
1.387GlyTyr: 1.387 ± 0.728
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.387HisAsp: 1.387 ± 0.641
0.693HisGlu: 0.693 ± 0.364
2.08HisPhe: 2.08 ± 0.277
2.774HisGly: 2.774 ± 0.087
0.693HisHis: 0.693 ± 0.364
2.774HisIle: 2.774 ± 1.457
2.08HisLys: 2.08 ± 0.277
2.774HisLeu: 2.774 ± 0.087
0.693HisMet: 0.693 ± 0.364
0.693HisAsn: 0.693 ± 0.364
0.693HisPro: 0.693 ± 1.005
0.0HisGln: 0.0 ± 0.0
2.08HisArg: 2.08 ± 1.093
0.693HisSer: 0.693 ± 0.364
2.08HisThr: 2.08 ± 1.646
1.387HisVal: 1.387 ± 0.728
1.387HisTrp: 1.387 ± 0.641
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.08IleAla: 2.08 ± 0.277
0.0IleCys: 0.0 ± 0.0
6.935IleAsp: 6.935 ± 0.903
3.467IleGlu: 3.467 ± 0.452
0.0IlePhe: 0.0 ± 0.0
2.08IleGly: 2.08 ± 1.093
2.08IleHis: 2.08 ± 1.093
2.774IleIle: 2.774 ± 1.457
0.693IleLys: 0.693 ± 0.364
6.935IleLeu: 6.935 ± 0.903
1.387IleMet: 1.387 ± 0.728
0.693IleAsn: 0.693 ± 0.364
2.774IlePro: 2.774 ± 0.087
1.387IleGln: 1.387 ± 0.728
4.854IleArg: 4.854 ± 0.189
3.467IleSer: 3.467 ± 1.821
0.693IleThr: 0.693 ± 0.364
0.693IleVal: 0.693 ± 0.364
0.0IleTrp: 0.0 ± 0.0
1.387IleTyr: 1.387 ± 0.641
0.0IleXaa: 0.0 ± 0.0
Lys
6.935LysAla: 6.935 ± 1.836
0.693LysCys: 0.693 ± 0.364
1.387LysAsp: 1.387 ± 0.728
2.08LysGlu: 2.08 ± 0.277
4.854LysPhe: 4.854 ± 1.18
0.693LysGly: 0.693 ± 0.364
1.387LysHis: 1.387 ± 0.641
2.08LysIle: 2.08 ± 0.277
4.854LysLys: 4.854 ± 0.189
5.548LysLeu: 5.548 ± 0.175
0.693LysMet: 0.693 ± 0.364
0.693LysAsn: 0.693 ± 0.364
2.08LysPro: 2.08 ± 1.093
0.693LysGln: 0.693 ± 0.364
2.08LysArg: 2.08 ± 0.277
2.774LysSer: 2.774 ± 0.087
1.387LysThr: 1.387 ± 0.728
2.08LysVal: 2.08 ± 1.093
1.387LysTrp: 1.387 ± 0.728
2.08LysTyr: 2.08 ± 1.093
0.0LysXaa: 0.0 ± 0.0
Leu
9.015LeuAla: 9.015 ± 3.482
0.0LeuCys: 0.0 ± 0.0
8.322LeuAsp: 8.322 ± 0.262
11.096LeuGlu: 11.096 ± 3.759
0.693LeuPhe: 0.693 ± 0.364
5.548LeuGly: 5.548 ± 1.544
0.0LeuHis: 0.0 ± 0.0
3.467LeuIle: 3.467 ± 0.452
6.935LeuLys: 6.935 ± 0.903
11.789LeuLeu: 11.789 ± 3.452
0.693LeuMet: 0.693 ± 0.364
6.935LeuAsn: 6.935 ± 0.466
3.467LeuPro: 3.467 ± 1.821
1.387LeuGln: 1.387 ± 0.728
9.709LeuArg: 9.709 ± 0.379
7.628LeuSer: 7.628 ± 4.006
4.854LeuThr: 4.854 ± 1.18
6.241LeuVal: 6.241 ± 2.2
2.774LeuTrp: 2.774 ± 1.457
3.467LeuTyr: 3.467 ± 0.452
0.0LeuXaa: 0.0 ± 0.0
Met
0.693MetAla: 0.693 ± 1.005
0.0MetCys: 0.0 ± 0.0
2.08MetAsp: 2.08 ± 0.277
0.693MetGlu: 0.693 ± 0.364
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
2.08MetHis: 2.08 ± 0.277
1.387MetIle: 1.387 ± 0.728
2.774MetLys: 2.774 ± 0.087
2.08MetLeu: 2.08 ± 1.093
1.387MetMet: 1.387 ± 0.936
0.693MetAsn: 0.693 ± 0.364
0.693MetPro: 0.693 ± 0.364
0.693MetGln: 0.693 ± 0.364
1.387MetArg: 1.387 ± 0.728
4.161MetSer: 4.161 ± 0.554
0.0MetThr: 0.0 ± 0.0
2.774MetVal: 2.774 ± 1.457
0.0MetTrp: 0.0 ± 0.0
0.693MetTyr: 0.693 ± 0.364
0.0MetXaa: 0.0 ± 0.0
Asn
2.08AsnAla: 2.08 ± 0.277
0.693AsnCys: 0.693 ± 0.364
1.387AsnAsp: 1.387 ± 0.728
4.854AsnGlu: 4.854 ± 1.559
2.08AsnPhe: 2.08 ± 0.277
0.693AsnGly: 0.693 ± 0.364
1.387AsnHis: 1.387 ± 0.728
1.387AsnIle: 1.387 ± 0.728
0.0AsnLys: 0.0 ± 0.0
6.241AsnLeu: 6.241 ± 0.539
0.0AsnMet: 0.0 ± 0.0
3.467AsnAsn: 3.467 ± 0.918
2.08AsnPro: 2.08 ± 1.093
2.08AsnGln: 2.08 ± 0.277
3.467AsnArg: 3.467 ± 0.918
2.08AsnSer: 2.08 ± 1.093
1.387AsnThr: 1.387 ± 0.641
2.774AsnVal: 2.774 ± 0.087
1.387AsnTrp: 1.387 ± 0.641
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
4.854ProAla: 4.854 ± 0.189
1.387ProCys: 1.387 ± 0.728
3.467ProAsp: 3.467 ± 0.452
2.08ProGlu: 2.08 ± 0.277
2.774ProPhe: 2.774 ± 1.457
8.322ProGly: 8.322 ± 2.477
0.693ProHis: 0.693 ± 0.364
0.693ProIle: 0.693 ± 0.364
0.693ProLys: 0.693 ± 0.364
7.628ProLeu: 7.628 ± 0.102
2.774ProMet: 2.774 ± 0.087
0.0ProAsn: 0.0 ± 0.0
4.854ProPro: 4.854 ± 2.928
0.693ProGln: 0.693 ± 0.364
2.08ProArg: 2.08 ± 0.277
2.774ProSer: 2.774 ± 1.282
2.08ProThr: 2.08 ± 0.277
2.08ProVal: 2.08 ± 0.277
0.0ProTrp: 0.0 ± 0.0
1.387ProTyr: 1.387 ± 0.728
0.0ProXaa: 0.0 ± 0.0
Gln
2.08GlnAla: 2.08 ± 1.093
0.0GlnCys: 0.0 ± 0.0
1.387GlnAsp: 1.387 ± 0.641
1.387GlnGlu: 1.387 ± 0.641
2.08GlnPhe: 2.08 ± 0.277
0.693GlnGly: 0.693 ± 0.364
0.693GlnHis: 0.693 ± 0.364
2.08GlnIle: 2.08 ± 0.277
0.693GlnLys: 0.693 ± 0.364
0.0GlnLeu: 0.0 ± 0.0
0.0GlnMet: 0.0 ± 0.0
1.387GlnAsn: 1.387 ± 0.728
3.467GlnPro: 3.467 ± 0.918
4.854GlnGln: 4.854 ± 0.189
4.854GlnArg: 4.854 ± 0.189
0.0GlnSer: 0.0 ± 0.0
2.08GlnThr: 2.08 ± 1.646
3.467GlnVal: 3.467 ± 0.918
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
10.402ArgAla: 10.402 ± 2.754
1.387ArgCys: 1.387 ± 0.728
5.548ArgAsp: 5.548 ± 2.564
2.774ArgGlu: 2.774 ± 1.457
4.854ArgPhe: 4.854 ± 1.18
3.467ArgGly: 3.467 ± 1.821
2.774ArgHis: 2.774 ± 0.087
1.387ArgIle: 1.387 ± 0.728
4.161ArgLys: 4.161 ± 0.554
9.709ArgLeu: 9.709 ± 1.748
1.387ArgMet: 1.387 ± 0.728
2.08ArgAsn: 2.08 ± 0.277
4.854ArgPro: 4.854 ± 1.18
2.08ArgGln: 2.08 ± 0.277
6.935ArgArg: 6.935 ± 1.836
2.774ArgSer: 2.774 ± 1.282
2.774ArgThr: 2.774 ± 0.087
8.322ArgVal: 8.322 ± 3.846
1.387ArgTrp: 1.387 ± 0.728
2.774ArgTyr: 2.774 ± 0.087
0.0ArgXaa: 0.0 ± 0.0
Ser
5.548SerAla: 5.548 ± 0.175
2.774SerCys: 2.774 ± 1.457
2.774SerAsp: 2.774 ± 1.457
1.387SerGlu: 1.387 ± 0.728
4.161SerPhe: 4.161 ± 0.816
3.467SerGly: 3.467 ± 0.452
2.08SerHis: 2.08 ± 0.277
2.774SerIle: 2.774 ± 0.087
4.161SerLys: 4.161 ± 0.816
6.241SerLeu: 6.241 ± 0.539
1.387SerMet: 1.387 ± 0.728
1.387SerAsn: 1.387 ± 0.728
2.08SerPro: 2.08 ± 0.277
3.467SerGln: 3.467 ± 0.918
2.774SerArg: 2.774 ± 0.087
3.467SerSer: 3.467 ± 0.918
1.387SerThr: 1.387 ± 0.728
0.693SerVal: 0.693 ± 0.364
0.693SerTrp: 0.693 ± 0.364
2.08SerTyr: 2.08 ± 0.277
0.0SerXaa: 0.0 ± 0.0
Thr
2.774ThrAla: 2.774 ± 1.282
1.387ThrCys: 1.387 ± 0.641
2.08ThrAsp: 2.08 ± 1.093
1.387ThrGlu: 1.387 ± 0.728
2.08ThrPhe: 2.08 ± 0.277
2.08ThrGly: 2.08 ± 1.646
2.08ThrHis: 2.08 ± 0.277
0.693ThrIle: 0.693 ± 0.364
1.387ThrLys: 1.387 ± 0.728
4.161ThrLeu: 4.161 ± 0.554
2.08ThrMet: 2.08 ± 0.277
1.387ThrAsn: 1.387 ± 0.641
2.08ThrPro: 2.08 ± 0.277
1.387ThrGln: 1.387 ± 0.641
6.241ThrArg: 6.241 ± 3.569
2.774ThrSer: 2.774 ± 1.457
5.548ThrThr: 5.548 ± 3.933
4.161ThrVal: 4.161 ± 1.923
2.08ThrTrp: 2.08 ± 0.277
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
6.241ValAla: 6.241 ± 0.83
0.0ValCys: 0.0 ± 0.0
2.774ValAsp: 2.774 ± 0.087
5.548ValGlu: 5.548 ± 2.564
2.08ValPhe: 2.08 ± 0.277
3.467ValGly: 3.467 ± 0.918
3.467ValHis: 3.467 ± 2.287
2.774ValIle: 2.774 ± 0.087
3.467ValLys: 3.467 ± 0.918
5.548ValLeu: 5.548 ± 1.544
1.387ValMet: 1.387 ± 0.728
1.387ValAsn: 1.387 ± 0.728
4.161ValPro: 4.161 ± 2.185
2.08ValGln: 2.08 ± 1.646
4.854ValArg: 4.854 ± 1.559
3.467ValSer: 3.467 ± 0.918
1.387ValThr: 1.387 ± 0.641
4.854ValVal: 4.854 ± 0.189
0.0ValTrp: 0.0 ± 0.0
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
0.693TrpAla: 0.693 ± 0.364
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
2.08TrpGlu: 2.08 ± 0.277
0.693TrpPhe: 0.693 ± 0.364
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
3.467TrpIle: 3.467 ± 0.452
2.774TrpLys: 2.774 ± 1.457
2.774TrpLeu: 2.774 ± 0.087
0.0TrpMet: 0.0 ± 0.0
2.08TrpAsn: 2.08 ± 0.277
0.693TrpPro: 0.693 ± 0.364
1.387TrpGln: 1.387 ± 0.728
2.08TrpArg: 2.08 ± 1.093
0.693TrpSer: 0.693 ± 0.364
2.08TrpThr: 2.08 ± 0.277
0.693TrpVal: 0.693 ± 0.364
1.387TrpTrp: 1.387 ± 0.641
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.08TyrAla: 2.08 ± 0.277
0.0TyrCys: 0.0 ± 0.0
0.0TyrAsp: 0.0 ± 0.0
2.774TyrGlu: 2.774 ± 0.087
0.0TyrPhe: 0.0 ± 0.0
0.693TyrGly: 0.693 ± 0.364
0.693TyrHis: 0.693 ± 0.364
1.387TyrIle: 1.387 ± 0.728
1.387TyrLys: 1.387 ± 0.641
3.467TyrLeu: 3.467 ± 1.821
0.693TyrMet: 0.693 ± 1.005
0.693TyrAsn: 0.693 ± 0.364
0.0TyrPro: 0.0 ± 0.0
0.0TyrGln: 0.0 ± 0.0
3.467TyrArg: 3.467 ± 0.452
0.693TyrSer: 0.693 ± 0.364
0.693TyrThr: 0.693 ± 0.364
0.0TyrVal: 0.0 ± 0.0
0.693TyrTrp: 0.693 ± 0.364
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1443 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski