Amino acid dipepetide frequency for Calocera viscosa (strain TUFC12733)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.208AlaAla: 10.208 ± 0.067	1.206AlaCys: 1.206 ± 0.02	4.365AlaAsp: 4.365 ± 0.034	5.524AlaGlu: 5.524 ± 0.041	3.321AlaPhe: 3.321 ± 0.031	6.532AlaGly: 6.532 ± 0.046	2.237AlaHis: 2.237 ± 0.022	4.062AlaIle: 4.062 ± 0.032	3.796AlaLys: 3.796 ± 0.036	9.46AlaLeu: 9.46 ± 0.051	2.135AlaMet: 2.135 ± 0.023	2.628AlaAsn: 2.628 ± 0.024	6.221AlaPro: 6.221 ± 0.057	3.844AlaGln: 3.844 ± 0.039	5.917AlaArg: 5.917 ± 0.043	7.539AlaSer: 7.539 ± 0.051	5.077AlaThr: 5.077 ± 0.035	5.956AlaVal: 5.956 ± 0.039	1.395AlaTrp: 1.395 ± 0.018	2.435AlaTyr: 2.435 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	1.089CysAla: 1.089 ± 0.017	0.269CysCys: 0.269 ± 0.009	0.622CysAsp: 0.622 ± 0.012	0.592CysGlu: 0.592 ± 0.011	0.516CysPhe: 0.516 ± 0.011	0.961CysGly: 0.961 ± 0.018	0.31CysHis: 0.31 ± 0.008	0.631CysIle: 0.631 ± 0.012	0.451CysLys: 0.451 ± 0.009	1.283CysLeu: 1.283 ± 0.017	0.309CysMet: 0.309 ± 0.008	0.383CysAsn: 0.383 ± 0.01	0.775CysPro: 0.775 ± 0.014	0.396CysGln: 0.396 ± 0.009	0.836CysArg: 0.836 ± 0.013	0.952CysSer: 0.952 ± 0.018	0.799CysThr: 0.799 ± 0.014	0.839CysVal: 0.839 ± 0.015	0.244CysTrp: 0.244 ± 0.006	0.317CysTyr: 0.317 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.952AspAla: 4.952 ± 0.035	0.583AspCys: 0.583 ± 0.013	3.758AspAsp: 3.758 ± 0.043	4.346AspGlu: 4.346 ± 0.043	1.9AspPhe: 1.9 ± 0.019	4.008AspGly: 4.008 ± 0.034	1.088AspHis: 1.088 ± 0.015	2.66AspIle: 2.66 ± 0.024	2.024AspLys: 2.024 ± 0.023	4.933AspLeu: 4.933 ± 0.036	1.283AspMet: 1.283 ± 0.018	1.441AspAsn: 1.441 ± 0.017	3.347AspPro: 3.347 ± 0.031	1.566AspGln: 1.566 ± 0.018	3.013AspArg: 3.013 ± 0.034	3.266AspSer: 3.266 ± 0.027	2.732AspThr: 2.732 ± 0.026	3.965AspVal: 3.965 ± 0.03	0.971AspTrp: 0.971 ± 0.016	1.398AspTyr: 1.398 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.498GluAla: 5.498 ± 0.047	0.629GluCys: 0.629 ± 0.012	4.192GluAsp: 4.192 ± 0.04	6.223GluGlu: 6.223 ± 0.058	1.714GluPhe: 1.714 ± 0.018	4.357GluGly: 4.357 ± 0.038	1.487GluHis: 1.487 ± 0.017	2.531GluIle: 2.531 ± 0.025	3.153GluLys: 3.153 ± 0.033	5.615GluLeu: 5.615 ± 0.04	1.524GluMet: 1.524 ± 0.017	1.653GluAsn: 1.653 ± 0.019	2.952GluPro: 2.952 ± 0.028	2.525GluGln: 2.525 ± 0.026	4.646GluArg: 4.646 ± 0.043	3.513GluSer: 3.513 ± 0.028	2.945GluThr: 2.945 ± 0.028	3.897GluVal: 3.897 ± 0.034	1.017GluTrp: 1.017 ± 0.017	1.497GluTyr: 1.497 ± 0.015	0.0GluXaa: 0.0 ± 0.0
Phe	3.091PheAla: 3.091 ± 0.026	0.525PheCys: 0.525 ± 0.011	2.075PheAsp: 2.075 ± 0.019	1.999PheGlu: 1.999 ± 0.023	1.45PhePhe: 1.45 ± 0.019	2.77PheGly: 2.77 ± 0.028	0.839PheHis: 0.839 ± 0.014	1.582PheIle: 1.582 ± 0.018	1.253PheLys: 1.253 ± 0.016	3.445PheLeu: 3.445 ± 0.03	0.705PheMet: 0.705 ± 0.012	1.18PheAsn: 1.18 ± 0.017	2.162PhePro: 2.162 ± 0.022	1.217PheGln: 1.217 ± 0.016	1.859PheArg: 1.859 ± 0.02	2.744PheSer: 2.744 ± 0.024	2.004PheThr: 2.004 ± 0.021	2.357PheVal: 2.357 ± 0.023	0.594PheTrp: 0.594 ± 0.012	0.984PheTyr: 0.984 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	6.072GlyAla: 6.072 ± 0.042	0.897GlyCys: 0.897 ± 0.016	3.465GlyAsp: 3.465 ± 0.031	4.317GlyGlu: 4.317 ± 0.037	2.55GlyPhe: 2.55 ± 0.024	5.998GlyGly: 5.998 ± 0.057	1.606GlyHis: 1.606 ± 0.022	3.249GlyIle: 3.249 ± 0.029	3.492GlyLys: 3.492 ± 0.031	6.14GlyLeu: 6.14 ± 0.036	1.834GlyMet: 1.834 ± 0.024	2.208GlyAsn: 2.208 ± 0.024	3.731GlyPro: 3.731 ± 0.035	2.572GlyGln: 2.572 ± 0.03	4.671GlyArg: 4.671 ± 0.037	5.451GlySer: 5.451 ± 0.041	4.304GlyThr: 4.304 ± 0.03	4.647GlyVal: 4.647 ± 0.037	1.38GlyTrp: 1.38 ± 0.019	2.003GlyTyr: 2.003 ± 0.019	0.0GlyXaa: 0.0 ± 0.0
His	2.273HisAla: 2.273 ± 0.022	0.348HisCys: 0.348 ± 0.01	1.164HisAsp: 1.164 ± 0.016	1.246HisGlu: 1.246 ± 0.015	0.862HisPhe: 0.862 ± 0.013	1.707HisGly: 1.707 ± 0.02	0.777HisHis: 0.777 ± 0.013	1.164HisIle: 1.164 ± 0.016	0.796HisLys: 0.796 ± 0.011	2.511HisLeu: 2.511 ± 0.024	0.531HisMet: 0.531 ± 0.01	0.686HisAsn: 0.686 ± 0.014	1.989HisPro: 1.989 ± 0.025	0.826HisGln: 0.826 ± 0.015	1.53HisArg: 1.53 ± 0.021	1.823HisSer: 1.823 ± 0.02	1.416HisThr: 1.416 ± 0.021	1.569HisVal: 1.569 ± 0.018	0.357HisTrp: 0.357 ± 0.008	0.685HisTyr: 0.685 ± 0.01	0.0HisXaa: 0.0 ± 0.0
Ile	4.094IleAla: 4.094 ± 0.029	0.673IleCys: 0.673 ± 0.012	2.444IleAsp: 2.444 ± 0.026	2.349IleGlu: 2.349 ± 0.025	1.677IlePhe: 1.677 ± 0.023	3.097IleGly: 3.097 ± 0.028	1.041IleHis: 1.041 ± 0.015	2.163IleIle: 2.163 ± 0.026	1.76IleLys: 1.76 ± 0.023	4.247IleLeu: 4.247 ± 0.038	0.961IleMet: 0.961 ± 0.014	1.401IleAsn: 1.401 ± 0.017	3.091IlePro: 3.091 ± 0.024	1.562IleGln: 1.562 ± 0.016	2.659IleArg: 2.659 ± 0.024	3.354IleSer: 3.354 ± 0.027	2.605IleThr: 2.605 ± 0.023	3.116IleVal: 3.116 ± 0.029	0.733IleTrp: 0.733 ± 0.015	1.165IleTyr: 1.165 ± 0.016	0.0IleXaa: 0.0 ± 0.0
Lys	4.016LysAla: 4.016 ± 0.034	0.41LysCys: 0.41 ± 0.009	2.242LysAsp: 2.242 ± 0.025	3.149LysGlu: 3.149 ± 0.033	1.169LysPhe: 1.169 ± 0.016	2.822LysGly: 2.822 ± 0.027	1.009LysHis: 1.009 ± 0.014	1.679LysIle: 1.679 ± 0.021	2.565LysLys: 2.565 ± 0.034	3.733LysLeu: 3.733 ± 0.032	0.89LysMet: 0.89 ± 0.012	1.168LysAsn: 1.168 ± 0.018	2.428LysPro: 2.428 ± 0.025	1.548LysGln: 1.548 ± 0.019	3.264LysArg: 3.264 ± 0.031	2.579LysSer: 2.579 ± 0.022	2.293LysThr: 2.293 ± 0.024	2.588LysVal: 2.588 ± 0.027	0.654LysTrp: 0.654 ± 0.013	1.129LysTyr: 1.129 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	9.019LeuAla: 9.019 ± 0.051	1.337LeuCys: 1.337 ± 0.018	5.216LeuAsp: 5.216 ± 0.035	5.572LeuGlu: 5.572 ± 0.048	3.36LeuPhe: 3.36 ± 0.029	6.385LeuGly: 6.385 ± 0.043	2.525LeuHis: 2.525 ± 0.026	3.815LeuIle: 3.815 ± 0.031	3.796LeuLys: 3.796 ± 0.028	9.873LeuLeu: 9.873 ± 0.06	1.897LeuMet: 1.897 ± 0.021	2.857LeuAsn: 2.857 ± 0.023	7.195LeuPro: 7.195 ± 0.046	3.878LeuGln: 3.878 ± 0.036	6.557LeuArg: 6.557 ± 0.047	7.939LeuSer: 7.939 ± 0.044	5.23LeuThr: 5.23 ± 0.034	5.806LeuVal: 5.806 ± 0.042	1.354LeuTrp: 1.354 ± 0.017	2.389LeuTyr: 2.389 ± 0.024	0.0LeuXaa: 0.0 ± 0.0
Met	2.071MetAla: 2.071 ± 0.019	0.267MetCys: 0.267 ± 0.007	1.334MetAsp: 1.334 ± 0.018	1.307MetGlu: 1.307 ± 0.02	0.752MetPhe: 0.752 ± 0.013	1.504MetGly: 1.504 ± 0.02	0.56MetHis: 0.56 ± 0.012	0.912MetIle: 0.912 ± 0.015	0.904MetLys: 0.904 ± 0.014	2.098MetLeu: 2.098 ± 0.021	0.57MetMet: 0.57 ± 0.01	0.696MetAsn: 0.696 ± 0.014	1.501MetPro: 1.501 ± 0.019	0.997MetGln: 0.997 ± 0.017	1.485MetArg: 1.485 ± 0.017	1.986MetSer: 1.986 ± 0.02	1.276MetThr: 1.276 ± 0.018	1.265MetVal: 1.265 ± 0.017	0.312MetTrp: 0.312 ± 0.009	0.542MetTyr: 0.542 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	2.919AsnAla: 2.919 ± 0.026	0.377AsnCys: 0.377 ± 0.01	1.481AsnAsp: 1.481 ± 0.018	1.586AsnGlu: 1.586 ± 0.019	1.086AsnPhe: 1.086 ± 0.016	2.609AsnGly: 2.609 ± 0.03	0.658AsnHis: 0.658 ± 0.011	1.571AsnIle: 1.571 ± 0.019	1.074AsnLys: 1.074 ± 0.014	2.802AsnLeu: 2.802 ± 0.027	0.732AsnMet: 0.732 ± 0.012	1.01AsnAsn: 1.01 ± 0.019	2.121AsnPro: 2.121 ± 0.026	1.003AsnGln: 1.003 ± 0.016	1.657AsnArg: 1.657 ± 0.021	2.0AsnSer: 2.0 ± 0.023	1.794AsnThr: 1.794 ± 0.02	2.179AsnVal: 2.179 ± 0.022	0.509AsnTrp: 0.509 ± 0.011	0.821AsnTyr: 0.821 ± 0.012	0.0AsnXaa: 0.0 ± 0.0
Pro	6.9ProAla: 6.9 ± 0.06	0.593ProCys: 0.593 ± 0.012	3.222ProAsp: 3.222 ± 0.027	3.901ProGlu: 3.901 ± 0.031	2.219ProPhe: 2.219 ± 0.024	4.459ProGly: 4.459 ± 0.045	1.62ProHis: 1.62 ± 0.022	2.643ProIle: 2.643 ± 0.026	2.34ProLys: 2.34 ± 0.024	5.926ProLeu: 5.926 ± 0.042	1.246ProMet: 1.246 ± 0.018	2.056ProAsn: 2.056 ± 0.023	7.027ProPro: 7.027 ± 0.093	2.512ProGln: 2.512 ± 0.034	3.89ProArg: 3.89 ± 0.035	7.112ProSer: 7.112 ± 0.06	4.666ProThr: 4.666 ± 0.039	4.083ProVal: 4.083 ± 0.032	0.844ProTrp: 0.844 ± 0.013	1.687ProTyr: 1.687 ± 0.021	0.0ProXaa: 0.0 ± 0.0
Gln	3.709GlnAla: 3.709 ± 0.036	0.501GlnCys: 0.501 ± 0.015	1.754GlnAsp: 1.754 ± 0.019	2.273GlnGlu: 2.273 ± 0.025	1.148GlnPhe: 1.148 ± 0.017	2.466GlnGly: 2.466 ± 0.026	1.067GlnHis: 1.067 ± 0.018	1.586GlnIle: 1.586 ± 0.018	1.488GlnLys: 1.488 ± 0.021	3.718GlnLeu: 3.718 ± 0.028	0.857GlnMet: 0.857 ± 0.014	1.156GlnAsn: 1.156 ± 0.017	2.654GlnPro: 2.654 ± 0.035	2.339GlnGln: 2.339 ± 0.072	2.622GlnArg: 2.622 ± 0.021	2.73GlnSer: 2.73 ± 0.025	2.066GlnThr: 2.066 ± 0.021	2.174GlnVal: 2.174 ± 0.022	0.593GlnTrp: 0.593 ± 0.011	1.081GlnTyr: 1.081 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.955ArgAla: 5.955 ± 0.044	0.8ArgCys: 0.8 ± 0.014	3.264ArgAsp: 3.264 ± 0.03	4.244ArgGlu: 4.244 ± 0.036	2.078ArgPhe: 2.078 ± 0.018	4.077ArgGly: 4.077 ± 0.035	1.566ArgHis: 1.566 ± 0.02	2.812ArgIle: 2.812 ± 0.023	3.109ArgLys: 3.109 ± 0.029	6.2ArgLeu: 6.2 ± 0.04	1.556ArgMet: 1.556 ± 0.018	1.867ArgAsn: 1.867 ± 0.02	4.096ArgPro: 4.096 ± 0.039	2.473ArgGln: 2.473 ± 0.026	5.58ArgArg: 5.58 ± 0.044	4.92ArgSer: 4.92 ± 0.039	3.751ArgThr: 3.751 ± 0.026	3.864ArgVal: 3.864 ± 0.03	1.109ArgTrp: 1.109 ± 0.017	1.711ArgTyr: 1.711 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	7.435SerAla: 7.435 ± 0.048	0.886SerCys: 0.886 ± 0.013	3.701SerAsp: 3.701 ± 0.028	3.664SerGlu: 3.664 ± 0.028	2.819SerPhe: 2.819 ± 0.027	5.499SerGly: 5.499 ± 0.043	1.861SerHis: 1.861 ± 0.022	3.477SerIle: 3.477 ± 0.03	2.835SerLys: 2.835 ± 0.024	7.687SerLeu: 7.687 ± 0.05	1.655SerMet: 1.655 ± 0.021	2.309SerAsn: 2.309 ± 0.024	6.313SerPro: 6.313 ± 0.06	2.734SerGln: 2.734 ± 0.025	4.716SerArg: 4.716 ± 0.035	8.263SerSer: 8.263 ± 0.078	5.41SerThr: 5.41 ± 0.043	4.634SerVal: 4.634 ± 0.026	1.041SerTrp: 1.041 ± 0.017	1.922SerTyr: 1.922 ± 0.022	0.0SerXaa: 0.0 ± 0.0
Thr	5.475ThrAla: 5.475 ± 0.041	0.771ThrCys: 0.771 ± 0.012	2.575ThrAsp: 2.575 ± 0.025	2.788ThrGlu: 2.788 ± 0.026	2.238ThrPhe: 2.238 ± 0.02	4.069ThrGly: 4.069 ± 0.031	1.326ThrHis: 1.326 ± 0.017	2.777ThrIle: 2.777 ± 0.031	2.091ThrLys: 2.091 ± 0.024	5.812ThrLeu: 5.812 ± 0.042	1.216ThrMet: 1.216 ± 0.014	1.729ThrAsn: 1.729 ± 0.019	4.761ThrPro: 4.761 ± 0.038	1.947ThrGln: 1.947 ± 0.022	3.355ThrArg: 3.355 ± 0.025	5.272ThrSer: 5.272 ± 0.044	3.898ThrThr: 3.898 ± 0.033	3.776ThrVal: 3.776 ± 0.028	0.886ThrTrp: 0.886 ± 0.013	1.581ThrTyr: 1.581 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	5.433ValAla: 5.433 ± 0.035	0.879ValCys: 0.879 ± 0.013	3.776ValAsp: 3.776 ± 0.029	4.017ValGlu: 4.017 ± 0.032	2.368ValPhe: 2.368 ± 0.024	4.213ValGly: 4.213 ± 0.032	1.633ValHis: 1.633 ± 0.017	2.89ValIle: 2.89 ± 0.032	2.691ValLys: 2.691 ± 0.027	6.523ValLeu: 6.523 ± 0.046	1.379ValMet: 1.379 ± 0.016	2.003ValAsn: 2.003 ± 0.022	4.269ValPro: 4.269 ± 0.034	2.552ValGln: 2.552 ± 0.021	4.073ValArg: 4.073 ± 0.032	4.497ValSer: 4.497 ± 0.03	3.453ValThr: 3.453 ± 0.028	4.516ValVal: 4.516 ± 0.035	1.041ValTrp: 1.041 ± 0.018	1.703ValTyr: 1.703 ± 0.018	0.0ValXaa: 0.0 ± 0.0
Trp	1.285TrpAla: 1.285 ± 0.016	0.23TrpCys: 0.23 ± 0.007	0.981TrpAsp: 0.981 ± 0.016	1.008TrpGlu: 1.008 ± 0.015	0.548TrpPhe: 0.548 ± 0.011	1.032TrpGly: 1.032 ± 0.014	0.384TrpHis: 0.384 ± 0.01	0.767TrpIle: 0.767 ± 0.014	0.772TrpLys: 0.772 ± 0.013	1.442TrpLeu: 1.442 ± 0.018	0.449TrpMet: 0.449 ± 0.009	0.619TrpAsn: 0.619 ± 0.011	0.747TrpPro: 0.747 ± 0.013	0.564TrpGln: 0.564 ± 0.011	1.117TrpArg: 1.117 ± 0.016	1.133TrpSer: 1.133 ± 0.017	0.998TrpThr: 0.998 ± 0.015	0.959TrpVal: 0.959 ± 0.015	0.328TrpTrp: 0.328 ± 0.008	0.441TrpTyr: 0.441 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.366TyrAla: 2.366 ± 0.025	0.394TyrCys: 0.394 ± 0.009	1.602TyrAsp: 1.602 ± 0.018	1.461TyrGlu: 1.461 ± 0.019	1.059TyrPhe: 1.059 ± 0.016	2.023TyrGly: 2.023 ± 0.022	0.669TyrHis: 0.669 ± 0.011	1.221TyrIle: 1.221 ± 0.018	0.945TyrLys: 0.945 ± 0.015	2.553TyrLeu: 2.553 ± 0.025	0.611TyrMet: 0.611 ± 0.011	0.938TyrAsn: 0.938 ± 0.014	1.566TyrPro: 1.566 ± 0.02	0.927TyrGln: 0.927 ± 0.014	1.582TyrArg: 1.582 ± 0.016	1.788TyrSer: 1.788 ± 0.02	1.626TyrThr: 1.626 ± 0.018	1.717TyrVal: 1.717 ± 0.019	0.443TyrTrp: 0.443 ± 0.01	0.853TyrTyr: 0.853 ± 0.016	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12323 proteins (5084671 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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