Amino acid dipepetide frequency for Xinzhou nematode virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.194AlaAla: 2.194 ± 0.92
1.371AlaCys: 1.371 ± 0.475
2.743AlaAsp: 2.743 ± 0.896
2.468AlaGlu: 2.468 ± 0.518
2.194AlaPhe: 2.194 ± 0.6
3.566AlaGly: 3.566 ± 1.227
1.371AlaHis: 1.371 ± 0.508
3.291AlaIle: 3.291 ± 0.565
3.291AlaLys: 3.291 ± 1.704
3.291AlaLeu: 3.291 ± 1.15
0.823AlaMet: 0.823 ± 0.548
1.92AlaAsn: 1.92 ± 0.977
2.468AlaPro: 2.468 ± 1.48
1.92AlaGln: 1.92 ± 0.87
2.468AlaArg: 2.468 ± 1.298
3.84AlaSer: 3.84 ± 1.683
3.017AlaThr: 3.017 ± 0.554
4.114AlaVal: 4.114 ± 1.579
0.0AlaTrp: 0.0 ± 0.0
1.097AlaTyr: 1.097 ± 0.355
0.0AlaXaa: 0.0 ± 0.0
Cys
1.371CysAla: 1.371 ± 0.508
0.549CysCys: 0.549 ± 0.683
1.097CysAsp: 1.097 ± 0.464
0.0CysGlu: 0.0 ± 0.0
0.823CysPhe: 0.823 ± 0.327
1.92CysGly: 1.92 ± 0.839
0.549CysHis: 0.549 ± 0.453
1.371CysIle: 1.371 ± 0.667
1.097CysLys: 1.097 ± 0.934
1.097CysLeu: 1.097 ± 0.446
0.0CysMet: 0.0 ± 0.0
0.549CysAsn: 0.549 ± 0.306
1.646CysPro: 1.646 ± 1.614
0.549CysGln: 0.549 ± 0.319
1.097CysArg: 1.097 ± 0.934
1.371CysSer: 1.371 ± 0.477
1.92CysThr: 1.92 ± 0.453
1.92CysVal: 1.92 ± 0.618
0.274CysTrp: 0.274 ± 0.153
1.097CysTyr: 1.097 ± 0.541
0.0CysXaa: 0.0 ± 0.0
Asp
2.468AspAla: 2.468 ± 0.388
1.371AspCys: 1.371 ± 0.831
1.92AspAsp: 1.92 ± 0.787
2.194AspGlu: 2.194 ± 0.89
2.194AspPhe: 2.194 ± 0.71
1.371AspGly: 1.371 ± 0.525
1.646AspHis: 1.646 ± 1.029
4.388AspIle: 4.388 ± 1.245
1.646AspLys: 1.646 ± 0.491
4.937AspLeu: 4.937 ± 1.562
1.371AspMet: 1.371 ± 1.093
1.646AspAsn: 1.646 ± 0.443
3.017AspPro: 3.017 ± 0.677
2.468AspGln: 2.468 ± 0.525
1.92AspArg: 1.92 ± 0.515
3.291AspSer: 3.291 ± 1.886
2.743AspThr: 2.743 ± 0.893
2.194AspVal: 2.194 ± 1.1
0.549AspTrp: 0.549 ± 0.453
1.371AspTyr: 1.371 ± 0.549
0.0AspXaa: 0.0 ± 0.0
Glu
2.468GluAla: 2.468 ± 1.363
1.097GluCys: 1.097 ± 0.906
3.017GluAsp: 3.017 ± 0.987
4.114GluGlu: 4.114 ± 1.357
4.663GluPhe: 4.663 ± 1.375
2.743GluGly: 2.743 ± 0.944
1.097GluHis: 1.097 ± 0.44
5.485GluIle: 5.485 ± 1.326
4.114GluLys: 4.114 ± 0.626
4.937GluLeu: 4.937 ± 1.505
2.194GluMet: 2.194 ± 0.551
2.194GluAsn: 2.194 ± 0.617
1.92GluPro: 1.92 ± 0.809
1.371GluGln: 1.371 ± 0.638
3.84GluArg: 3.84 ± 1.016
7.131GluSer: 7.131 ± 1.864
1.92GluThr: 1.92 ± 0.518
3.566GluVal: 3.566 ± 0.795
0.549GluTrp: 0.549 ± 0.453
2.743GluTyr: 2.743 ± 0.797
0.0GluXaa: 0.0 ± 0.0
Phe
2.468PheAla: 2.468 ± 0.767
1.097PheCys: 1.097 ± 0.355
2.194PheAsp: 2.194 ± 0.629
2.468PheGlu: 2.468 ± 0.856
1.097PhePhe: 1.097 ± 0.541
2.194PheGly: 2.194 ± 0.798
1.92PheHis: 1.92 ± 0.771
3.017PheIle: 3.017 ± 0.729
3.566PheLys: 3.566 ± 0.326
5.76PheLeu: 5.76 ± 1.403
0.549PheMet: 0.549 ± 0.306
2.194PheAsn: 2.194 ± 0.89
2.743PhePro: 2.743 ± 0.533
2.194PheGln: 2.194 ± 0.629
1.92PheArg: 1.92 ± 0.787
3.291PheSer: 3.291 ± 0.882
2.468PheThr: 2.468 ± 0.931
2.743PheVal: 2.743 ± 0.689
1.097PheTrp: 1.097 ± 0.541
1.92PheTyr: 1.92 ± 0.795
0.0PheXaa: 0.0 ± 0.0
Gly
1.92GlyAla: 1.92 ± 0.926
0.274GlyCys: 0.274 ± 0.153
1.646GlyAsp: 1.646 ± 0.443
2.194GlyGlu: 2.194 ± 1.195
1.92GlyPhe: 1.92 ± 0.788
2.743GlyGly: 2.743 ± 1.205
1.371GlyHis: 1.371 ± 0.65
6.034GlyIle: 6.034 ± 0.954
3.84GlyLys: 3.84 ± 0.754
6.034GlyLeu: 6.034 ± 1.892
1.646GlyMet: 1.646 ± 0.498
2.468GlyAsn: 2.468 ± 0.734
1.371GlyPro: 1.371 ± 0.472
3.566GlyGln: 3.566 ± 0.604
1.646GlyArg: 1.646 ± 0.635
5.76GlySer: 5.76 ± 1.631
3.017GlyThr: 3.017 ± 0.614
3.291GlyVal: 3.291 ± 0.712
0.823GlyTrp: 0.823 ± 0.444
1.097GlyTyr: 1.097 ± 0.639
0.0GlyXaa: 0.0 ± 0.0
His
0.823HisAla: 0.823 ± 1.061
0.549HisCys: 0.549 ± 0.319
1.097HisAsp: 1.097 ± 0.399
1.371HisGlu: 1.371 ± 0.568
1.371HisPhe: 1.371 ± 0.567
0.549HisGly: 0.549 ± 0.622
1.371HisHis: 1.371 ± 0.477
2.468HisIle: 2.468 ± 0.734
1.097HisLys: 1.097 ± 0.504
4.663HisLeu: 4.663 ± 1.279
0.823HisMet: 0.823 ± 0.741
0.549HisAsn: 0.549 ± 0.306
3.84HisPro: 3.84 ± 1.266
1.371HisGln: 1.371 ± 0.408
1.371HisArg: 1.371 ± 0.472
1.646HisSer: 1.646 ± 0.432
0.549HisThr: 0.549 ± 0.64
1.371HisVal: 1.371 ± 0.549
0.823HisTrp: 0.823 ± 0.327
1.646HisTyr: 1.646 ± 0.43
0.0HisXaa: 0.0 ± 0.0
Ile
2.743IleAla: 2.743 ± 0.744
2.468IleCys: 2.468 ± 0.828
4.937IleAsp: 4.937 ± 1.291
4.388IleGlu: 4.388 ± 0.669
3.291IlePhe: 3.291 ± 1.065
4.937IleGly: 4.937 ± 0.434
1.097IleHis: 1.097 ± 0.44
3.566IleIle: 3.566 ± 0.895
4.663IleLys: 4.663 ± 0.338
5.485IleLeu: 5.485 ± 0.66
2.194IleMet: 2.194 ± 0.475
3.017IleAsn: 3.017 ± 0.931
5.76IlePro: 5.76 ± 0.642
3.84IleGln: 3.84 ± 0.631
3.84IleArg: 3.84 ± 1.135
7.954IleSer: 7.954 ± 1.625
2.468IleThr: 2.468 ± 0.821
3.291IleVal: 3.291 ± 0.627
0.549IleTrp: 0.549 ± 0.27
1.646IleTyr: 1.646 ± 0.552
0.0IleXaa: 0.0 ± 0.0
Lys
3.84LysAla: 3.84 ± 1.695
1.646LysCys: 1.646 ± 0.883
1.92LysAsp: 1.92 ± 1.371
5.485LysGlu: 5.485 ± 0.9
3.017LysPhe: 3.017 ± 1.844
3.566LysGly: 3.566 ± 0.789
1.371LysHis: 1.371 ± 0.568
2.743LysIle: 2.743 ± 0.656
3.291LysLys: 3.291 ± 0.827
7.405LysLeu: 7.405 ± 0.728
1.92LysMet: 1.92 ± 0.503
3.017LysAsn: 3.017 ± 1.182
2.194LysPro: 2.194 ± 0.563
1.097LysGln: 1.097 ± 0.611
1.92LysArg: 1.92 ± 0.542
5.485LysSer: 5.485 ± 1.364
2.468LysThr: 2.468 ± 0.644
4.388LysVal: 4.388 ± 0.671
1.371LysTrp: 1.371 ± 0.764
1.371LysTyr: 1.371 ± 0.472
0.0LysXaa: 0.0 ± 0.0
Leu
9.051LeuAla: 9.051 ± 2.043
0.823LeuCys: 0.823 ± 0.891
3.017LeuAsp: 3.017 ± 0.74
7.405LeuGlu: 7.405 ± 1.666
5.211LeuPhe: 5.211 ± 0.492
7.954LeuGly: 7.954 ± 1.473
2.194LeuHis: 2.194 ± 0.95
7.405LeuIle: 7.405 ± 1.905
5.485LeuLys: 5.485 ± 1.311
14.262LeuLeu: 14.262 ± 2.449
3.84LeuMet: 3.84 ± 0.728
4.937LeuAsn: 4.937 ± 1.406
3.291LeuPro: 3.291 ± 0.767
2.194LeuGln: 2.194 ± 0.918
6.857LeuArg: 6.857 ± 0.475
10.422LeuSer: 10.422 ± 0.777
7.68LeuThr: 7.68 ± 1.514
4.663LeuVal: 4.663 ± 1.208
0.274LeuTrp: 0.274 ± 0.153
3.566LeuTyr: 3.566 ± 0.917
0.0LeuXaa: 0.0 ± 0.0
Met
1.097MetAla: 1.097 ± 1.058
0.274MetCys: 0.274 ± 0.342
1.371MetAsp: 1.371 ± 0.667
1.097MetGlu: 1.097 ± 0.399
0.823MetPhe: 0.823 ± 0.52
1.371MetGly: 1.371 ± 0.477
0.274MetHis: 0.274 ± 0.484
2.194MetIle: 2.194 ± 0.617
1.92MetLys: 1.92 ± 0.722
2.468MetLeu: 2.468 ± 1.324
0.274MetMet: 0.274 ± 0.342
1.646MetAsn: 1.646 ± 0.605
0.823MetPro: 0.823 ± 0.444
0.549MetGln: 0.549 ± 0.306
0.549MetArg: 0.549 ± 0.27
2.743MetSer: 2.743 ± 1.248
1.646MetThr: 1.646 ± 0.606
0.823MetVal: 0.823 ± 0.458
0.274MetTrp: 0.274 ± 0.153
1.371MetTyr: 1.371 ± 0.764
0.0MetXaa: 0.0 ± 0.0
Asn
1.371AsnAla: 1.371 ± 0.998
0.274AsnCys: 0.274 ± 0.379
1.371AsnAsp: 1.371 ± 0.764
3.566AsnGlu: 3.566 ± 2.018
1.646AsnPhe: 1.646 ± 0.917
1.371AsnGly: 1.371 ± 0.472
2.194AsnHis: 2.194 ± 0.971
4.388AsnIle: 4.388 ± 0.863
1.92AsnLys: 1.92 ± 0.679
6.583AsnLeu: 6.583 ± 1.904
1.097AsnMet: 1.097 ± 0.388
1.371AsnAsn: 1.371 ± 0.764
3.017AsnPro: 3.017 ± 1.136
1.371AsnGln: 1.371 ± 0.418
0.549AsnArg: 0.549 ± 0.27
3.84AsnSer: 3.84 ± 1.426
2.468AsnThr: 2.468 ± 0.688
3.017AsnVal: 3.017 ± 0.767
1.646AsnTrp: 1.646 ± 0.635
1.371AsnTyr: 1.371 ± 0.508
0.0AsnXaa: 0.0 ± 0.0
Pro
1.646ProAla: 1.646 ± 0.832
0.549ProCys: 0.549 ± 0.27
1.92ProAsp: 1.92 ± 0.453
2.743ProGlu: 2.743 ± 0.447
1.097ProPhe: 1.097 ± 0.313
2.194ProGly: 2.194 ± 1.623
3.017ProHis: 3.017 ± 0.632
4.388ProIle: 4.388 ± 0.548
2.468ProLys: 2.468 ± 0.856
6.308ProLeu: 6.308 ± 0.773
0.823ProMet: 0.823 ± 0.276
2.194ProAsn: 2.194 ± 0.617
3.84ProPro: 3.84 ± 1.583
0.823ProGln: 0.823 ± 0.4
1.646ProArg: 1.646 ± 0.958
4.937ProSer: 4.937 ± 1.454
3.84ProThr: 3.84 ± 0.84
3.291ProVal: 3.291 ± 1.652
0.549ProTrp: 0.549 ± 0.306
2.743ProTyr: 2.743 ± 0.616
0.0ProXaa: 0.0 ± 0.0
Gln
0.823GlnAla: 0.823 ± 0.444
0.823GlnCys: 0.823 ± 0.276
1.646GlnAsp: 1.646 ± 0.635
1.646GlnGlu: 1.646 ± 0.655
3.017GlnPhe: 3.017 ± 0.993
1.097GlnGly: 1.097 ± 0.611
1.646GlnHis: 1.646 ± 0.572
2.194GlnIle: 2.194 ± 0.71
2.194GlnLys: 2.194 ± 0.794
3.566GlnLeu: 3.566 ± 0.575
1.371GlnMet: 1.371 ± 0.65
1.92GlnAsn: 1.92 ± 0.44
1.371GlnPro: 1.371 ± 0.568
1.097GlnGln: 1.097 ± 1.528
1.646GlnArg: 1.646 ± 1.033
4.114GlnSer: 4.114 ± 0.603
0.823GlnThr: 0.823 ± 0.684
1.92GlnVal: 1.92 ± 1.745
0.274GlnTrp: 0.274 ± 0.153
1.097GlnTyr: 1.097 ± 0.399
0.0GlnXaa: 0.0 ± 0.0
Arg
3.017ArgAla: 3.017 ± 1.206
0.549ArgCys: 0.549 ± 0.306
3.017ArgAsp: 3.017 ± 0.984
4.114ArgGlu: 4.114 ± 0.887
1.097ArgPhe: 1.097 ± 0.611
2.194ArgGly: 2.194 ± 0.605
1.646ArgHis: 1.646 ± 0.964
2.194ArgIle: 2.194 ± 0.819
1.92ArgLys: 1.92 ± 0.542
3.84ArgLeu: 3.84 ± 0.195
1.097ArgMet: 1.097 ± 0.428
1.646ArgAsn: 1.646 ± 0.339
1.646ArgPro: 1.646 ± 0.907
1.92ArgGln: 1.92 ± 0.746
2.468ArgArg: 2.468 ± 1.114
4.663ArgSer: 4.663 ± 0.826
3.017ArgThr: 3.017 ± 0.771
1.097ArgVal: 1.097 ± 0.611
0.823ArgTrp: 0.823 ± 0.327
2.194ArgTyr: 2.194 ± 0.618
0.0ArgXaa: 0.0 ± 0.0
Ser
3.291SerAla: 3.291 ± 1.689
1.371SerCys: 1.371 ± 0.472
3.84SerAsp: 3.84 ± 1.26
4.388SerGlu: 4.388 ± 0.638
4.937SerPhe: 4.937 ± 0.878
3.291SerGly: 3.291 ± 0.405
2.743SerHis: 2.743 ± 0.854
6.308SerIle: 6.308 ± 1.329
7.68SerLys: 7.68 ± 1.545
11.794SerLeu: 11.794 ± 2.374
1.097SerMet: 1.097 ± 0.462
4.114SerAsn: 4.114 ± 1.326
4.663SerPro: 4.663 ± 0.387
2.194SerGln: 2.194 ± 0.817
3.017SerArg: 3.017 ± 0.318
8.228SerSer: 8.228 ± 1.753
7.131SerThr: 7.131 ± 3.065
6.583SerVal: 6.583 ± 2.038
1.646SerTrp: 1.646 ± 0.917
3.566SerTyr: 3.566 ± 0.724
0.0SerXaa: 0.0 ± 0.0
Thr
1.92ThrAla: 1.92 ± 0.515
0.823ThrCys: 0.823 ± 0.276
2.743ThrAsp: 2.743 ± 1.181
3.566ThrGlu: 3.566 ± 1.218
3.017ThrPhe: 3.017 ± 0.614
3.84ThrGly: 3.84 ± 0.658
1.92ThrHis: 1.92 ± 0.542
1.646ThrIle: 1.646 ± 0.43
2.743ThrLys: 2.743 ± 1.05
7.954ThrLeu: 7.954 ± 1.161
1.371ThrMet: 1.371 ± 0.549
2.194ThrAsn: 2.194 ± 0.913
3.291ThrPro: 3.291 ± 1.436
3.017ThrGln: 3.017 ± 1.365
2.743ThrArg: 2.743 ± 0.535
3.84ThrSer: 3.84 ± 1.811
4.937ThrThr: 4.937 ± 1.986
4.114ThrVal: 4.114 ± 1.597
1.646ThrTrp: 1.646 ± 0.635
1.371ThrTyr: 1.371 ± 0.43
0.0ThrXaa: 0.0 ± 0.0
Val
3.291ValAla: 3.291 ± 1.897
2.468ValCys: 2.468 ± 0.592
3.017ValAsp: 3.017 ± 0.4
5.211ValGlu: 5.211 ± 1.288
2.194ValPhe: 2.194 ± 0.302
3.017ValGly: 3.017 ± 0.884
0.823ValHis: 0.823 ± 0.597
6.034ValIle: 6.034 ± 0.663
3.017ValLys: 3.017 ± 0.709
6.034ValLeu: 6.034 ± 1.355
0.549ValMet: 0.549 ± 0.453
2.468ValAsn: 2.468 ± 0.982
1.92ValPro: 1.92 ± 0.618
1.097ValGln: 1.097 ± 0.639
2.743ValArg: 2.743 ± 0.78
4.388ValSer: 4.388 ± 1.817
3.017ValThr: 3.017 ± 0.928
2.468ValVal: 2.468 ± 0.702
1.097ValTrp: 1.097 ± 0.355
2.194ValTyr: 2.194 ± 0.781
0.0ValXaa: 0.0 ± 0.0
Trp
0.274TrpAla: 0.274 ± 0.153
0.549TrpCys: 0.549 ± 0.319
0.549TrpAsp: 0.549 ± 0.64
1.371TrpGlu: 1.371 ± 0.508
0.823TrpPhe: 0.823 ± 0.276
0.823TrpGly: 0.823 ± 0.458
0.549TrpHis: 0.549 ± 0.453
1.097TrpIle: 1.097 ± 0.313
1.371TrpLys: 1.371 ± 0.475
1.371TrpLeu: 1.371 ± 0.764
0.274TrpMet: 0.274 ± 0.153
2.194TrpAsn: 2.194 ± 1.223
0.274TrpPro: 0.274 ± 0.153
0.0TrpGln: 0.0 ± 0.0
0.274TrpArg: 0.274 ± 0.153
1.097TrpSer: 1.097 ± 0.355
1.371TrpThr: 1.371 ± 0.567
0.549TrpVal: 0.549 ± 0.306
0.274TrpTrp: 0.274 ± 0.153
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.371TyrAla: 1.371 ± 0.472
1.371TyrCys: 1.371 ± 0.43
1.646TyrAsp: 1.646 ± 0.566
1.371TyrGlu: 1.371 ± 0.764
2.468TyrPhe: 2.468 ± 0.465
1.92TyrGly: 1.92 ± 0.771
0.549TyrHis: 0.549 ± 0.306
1.92TyrIle: 1.92 ± 0.552
2.194TyrLys: 2.194 ± 0.555
3.017TyrLeu: 3.017 ± 0.614
0.0TyrMet: 0.0 ± 0.0
2.194TyrAsn: 2.194 ± 0.864
1.92TyrPro: 1.92 ± 0.44
1.646TyrGln: 1.646 ± 0.917
1.646TyrArg: 1.646 ± 1.169
3.84TyrSer: 3.84 ± 0.957
2.194TyrThr: 2.194 ± 0.466
1.646TyrVal: 1.646 ± 0.339
0.549TyrTrp: 0.549 ± 0.622
1.646TyrTyr: 1.646 ± 0.917
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3647 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski