Amino acid dipepetide frequency for Bosea lathyri

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.053AlaAla: 18.053 ± 0.145	1.118AlaCys: 1.118 ± 0.028	6.432AlaAsp: 6.432 ± 0.071	7.338AlaGlu: 7.338 ± 0.083	4.867AlaPhe: 4.867 ± 0.052	11.756AlaGly: 11.756 ± 0.097	2.151AlaHis: 2.151 ± 0.038	7.202AlaIle: 7.202 ± 0.074	4.411AlaLys: 4.411 ± 0.071	14.792AlaLeu: 14.792 ± 0.114	3.806AlaMet: 3.806 ± 0.046	2.901AlaAsn: 2.901 ± 0.044	5.906AlaPro: 5.906 ± 0.067	4.329AlaGln: 4.329 ± 0.061	9.23AlaArg: 9.23 ± 0.084	6.98AlaSer: 6.98 ± 0.073	6.582AlaThr: 6.582 ± 0.069	9.025AlaVal: 9.025 ± 0.08	1.481AlaTrp: 1.481 ± 0.029	2.584AlaTyr: 2.584 ± 0.04	0.0AlaXaa: 0.0 ± 0.0
Cys	0.956CysAla: 0.956 ± 0.025	0.094CysCys: 0.094 ± 0.007	0.501CysAsp: 0.501 ± 0.02	0.414CysGlu: 0.414 ± 0.015	0.317CysPhe: 0.317 ± 0.014	0.911CysGly: 0.911 ± 0.025	0.216CysHis: 0.216 ± 0.011	0.407CysIle: 0.407 ± 0.016	0.181CysLys: 0.181 ± 0.012	0.808CysLeu: 0.808 ± 0.023	0.14CysMet: 0.14 ± 0.008	0.178CysAsn: 0.178 ± 0.011	0.384CysPro: 0.384 ± 0.014	0.201CysGln: 0.201 ± 0.011	0.584CysArg: 0.584 ± 0.02	0.443CysSer: 0.443 ± 0.018	0.363CysThr: 0.363 ± 0.016	0.617CysVal: 0.617 ± 0.02	0.113CysTrp: 0.113 ± 0.008	0.165CysTyr: 0.165 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	6.76AspAla: 6.76 ± 0.067	0.433AspCys: 0.433 ± 0.018	2.806AspAsp: 2.806 ± 0.054	3.301AspGlu: 3.301 ± 0.047	2.033AspPhe: 2.033 ± 0.033	5.081AspGly: 5.081 ± 0.07	1.124AspHis: 1.124 ± 0.027	3.029AspIle: 3.029 ± 0.045	1.698AspLys: 1.698 ± 0.038	5.65AspLeu: 5.65 ± 0.065	1.184AspMet: 1.184 ± 0.029	1.146AspAsn: 1.146 ± 0.03	3.31AspPro: 3.31 ± 0.045	1.456AspGln: 1.456 ± 0.033	3.903AspArg: 3.903 ± 0.056	2.054AspSer: 2.054 ± 0.037	2.362AspThr: 2.362 ± 0.042	3.984AspVal: 3.984 ± 0.056	0.892AspTrp: 0.892 ± 0.025	1.323AspTyr: 1.323 ± 0.027	0.0AspXaa: 0.0 ± 0.0
Glu	7.865GluAla: 7.865 ± 0.083	0.324GluCys: 0.324 ± 0.016	2.333GluAsp: 2.333 ± 0.034	2.644GluGlu: 2.644 ± 0.04	1.703GluPhe: 1.703 ± 0.03	4.074GluGly: 4.074 ± 0.051	1.079GluHis: 1.079 ± 0.024	3.516GluIle: 3.516 ± 0.047	1.928GluLys: 1.928 ± 0.039	5.236GluLeu: 5.236 ± 0.065	1.42GluMet: 1.42 ± 0.027	1.29GluAsn: 1.29 ± 0.028	2.98GluPro: 2.98 ± 0.042	1.931GluGln: 1.931 ± 0.038	5.029GluArg: 5.029 ± 0.061	2.263GluSer: 2.263 ± 0.035	3.394GluThr: 3.394 ± 0.051	3.552GluVal: 3.552 ± 0.053	0.625GluTrp: 0.625 ± 0.018	0.82GluTyr: 0.82 ± 0.022	0.0GluXaa: 0.0 ± 0.0
Phe	4.942PheAla: 4.942 ± 0.055	0.373PheCys: 0.373 ± 0.015	2.521PheAsp: 2.521 ± 0.042	2.084PheGlu: 2.084 ± 0.036	1.362PhePhe: 1.362 ± 0.034	3.896PheGly: 3.896 ± 0.048	0.747PheHis: 0.747 ± 0.02	1.718PheIle: 1.718 ± 0.033	1.06PheLys: 1.06 ± 0.028	3.344PheLeu: 3.344 ± 0.047	0.823PheMet: 0.823 ± 0.02	1.015PheAsn: 1.015 ± 0.025	1.65PhePro: 1.65 ± 0.033	0.99PheGln: 0.99 ± 0.026	2.353PheArg: 2.353 ± 0.04	2.209PheSer: 2.209 ± 0.033	1.861PheThr: 1.861 ± 0.038	3.021PheVal: 3.021 ± 0.048	0.546PheTrp: 0.546 ± 0.02	0.823PheTyr: 0.823 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	9.926GlyAla: 9.926 ± 0.09	0.841GlyCys: 0.841 ± 0.024	4.289GlyAsp: 4.289 ± 0.06	4.797GlyGlu: 4.797 ± 0.067	3.868GlyPhe: 3.868 ± 0.048	7.724GlyGly: 7.724 ± 0.115	1.943GlyHis: 1.943 ± 0.038	4.719GlyIle: 4.719 ± 0.056	3.341GlyLys: 3.341 ± 0.048	9.841GlyLeu: 9.841 ± 0.081	2.261GlyMet: 2.261 ± 0.035	2.051GlyAsn: 2.051 ± 0.044	3.731GlyPro: 3.731 ± 0.053	2.967GlyGln: 2.967 ± 0.049	6.565GlyArg: 6.565 ± 0.067	4.921GlySer: 4.921 ± 0.056	4.563GlyThr: 4.563 ± 0.062	6.284GlyVal: 6.284 ± 0.065	1.394GlyTrp: 1.394 ± 0.033	2.302GlyTyr: 2.302 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	2.342HisAla: 2.342 ± 0.046	0.201HisCys: 0.201 ± 0.011	1.203HisAsp: 1.203 ± 0.026	1.028HisGlu: 1.028 ± 0.024	0.767HisPhe: 0.767 ± 0.022	1.909HisGly: 1.909 ± 0.037	0.532HisHis: 0.532 ± 0.022	0.876HisIle: 0.876 ± 0.019	0.481HisLys: 0.481 ± 0.017	2.001HisLeu: 2.001 ± 0.033	0.453HisMet: 0.453 ± 0.015	0.403HisAsn: 0.403 ± 0.017	1.251HisPro: 1.251 ± 0.03	0.509HisGln: 0.509 ± 0.017	1.338HisArg: 1.338 ± 0.027	0.866HisSer: 0.866 ± 0.026	0.693HisThr: 0.693 ± 0.021	1.51HisVal: 1.51 ± 0.035	0.313HisTrp: 0.313 ± 0.012	0.501HisTyr: 0.501 ± 0.015	0.0HisXaa: 0.0 ± 0.0
Ile	8.271IleAla: 8.271 ± 0.079	0.535IleCys: 0.535 ± 0.019	3.439IleAsp: 3.439 ± 0.048	3.557IleGlu: 3.557 ± 0.045	1.697IlePhe: 1.697 ± 0.036	5.407IleGly: 5.407 ± 0.064	0.861IleHis: 0.861 ± 0.024	2.389IleIle: 2.389 ± 0.043	1.562IleLys: 1.562 ± 0.036	4.645IleLeu: 4.645 ± 0.061	0.998IleMet: 0.998 ± 0.026	1.276IleAsn: 1.276 ± 0.029	2.345IlePro: 2.345 ± 0.04	1.21IleGln: 1.21 ± 0.025	3.182IleArg: 3.182 ± 0.046	2.862IleSer: 2.862 ± 0.041	2.621IleThr: 2.621 ± 0.041	4.786IleVal: 4.786 ± 0.061	0.64IleTrp: 0.64 ± 0.021	1.067IleTyr: 1.067 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	4.633LysAla: 4.633 ± 0.062	0.126LysCys: 0.126 ± 0.009	1.627LysAsp: 1.627 ± 0.034	1.412LysGlu: 1.412 ± 0.034	0.839LysPhe: 0.839 ± 0.024	2.667LysGly: 2.667 ± 0.044	0.548LysHis: 0.548 ± 0.017	1.667LysIle: 1.667 ± 0.032	1.065LysLys: 1.065 ± 0.033	3.506LysLeu: 3.506 ± 0.045	0.65LysMet: 0.65 ± 0.02	0.763LysAsn: 0.763 ± 0.022	2.289LysPro: 2.289 ± 0.043	1.034LysGln: 1.034 ± 0.026	2.446LysArg: 2.446 ± 0.045	1.796LysSer: 1.796 ± 0.038	1.924LysThr: 1.924 ± 0.033	2.411LysVal: 2.411 ± 0.042	0.32LysTrp: 0.32 ± 0.014	0.501LysTyr: 0.501 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	15.085LeuAla: 15.085 ± 0.119	0.874LeuCys: 0.874 ± 0.023	6.175LeuAsp: 6.175 ± 0.066	4.77LeuGlu: 4.77 ± 0.057	3.644LeuPhe: 3.644 ± 0.049	9.088LeuGly: 9.088 ± 0.095	1.788LeuHis: 1.788 ± 0.03	5.352LeuIle: 5.352 ± 0.061	3.731LeuLys: 3.731 ± 0.051	9.97LeuLeu: 9.97 ± 0.125	2.357LeuMet: 2.357 ± 0.035	2.495LeuAsn: 2.495 ± 0.041	5.912LeuPro: 5.912 ± 0.071	2.639LeuGln: 2.639 ± 0.037	7.015LeuArg: 7.015 ± 0.075	6.619LeuSer: 6.619 ± 0.067	5.711LeuThr: 5.711 ± 0.064	7.952LeuVal: 7.952 ± 0.073	1.208LeuTrp: 1.208 ± 0.03	1.945LeuTyr: 1.945 ± 0.036	0.0LeuXaa: 0.0 ± 0.0
Met	3.152MetAla: 3.152 ± 0.045	0.144MetCys: 0.144 ± 0.009	0.995MetAsp: 0.995 ± 0.025	0.9MetGlu: 0.9 ± 0.022	0.657MetPhe: 0.657 ± 0.021	1.689MetGly: 1.689 ± 0.033	0.391MetHis: 0.391 ± 0.014	1.382MetIle: 1.382 ± 0.029	0.912MetLys: 0.912 ± 0.022	2.626MetLeu: 2.626 ± 0.04	0.618MetMet: 0.618 ± 0.02	0.748MetAsn: 0.748 ± 0.021	1.551MetPro: 1.551 ± 0.033	0.768MetGln: 0.768 ± 0.024	1.854MetArg: 1.854 ± 0.029	1.703MetSer: 1.703 ± 0.033	1.911MetThr: 1.911 ± 0.036	1.711MetVal: 1.711 ± 0.033	0.17MetTrp: 0.17 ± 0.01	0.268MetTyr: 0.268 ± 0.013	0.0MetXaa: 0.0 ± 0.0
Asn	3.127AsnAla: 3.127 ± 0.046	0.215AsnCys: 0.215 ± 0.013	1.268AsnAsp: 1.268 ± 0.038	1.156AsnGlu: 1.156 ± 0.025	0.855AsnPhe: 0.855 ± 0.021	2.316AsnGly: 2.316 ± 0.046	0.456AsnHis: 0.456 ± 0.017	1.177AsnIle: 1.177 ± 0.026	0.664AsnLys: 0.664 ± 0.021	2.548AsnLeu: 2.548 ± 0.031	0.528AsnMet: 0.528 ± 0.017	0.632AsnAsn: 0.632 ± 0.022	1.752AsnPro: 1.752 ± 0.033	0.702AsnGln: 0.702 ± 0.02	1.649AsnArg: 1.649 ± 0.031	1.144AsnSer: 1.144 ± 0.027	1.174AsnThr: 1.174 ± 0.03	1.807AsnVal: 1.807 ± 0.03	0.423AsnTrp: 0.423 ± 0.018	0.601AsnTyr: 0.601 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	6.974ProAla: 6.974 ± 0.078	0.306ProCys: 0.306 ± 0.013	3.394ProAsp: 3.394 ± 0.043	3.593ProGlu: 3.593 ± 0.047	2.093ProPhe: 2.093 ± 0.04	4.727ProGly: 4.727 ± 0.062	1.103ProHis: 1.103 ± 0.027	2.468ProIle: 2.468 ± 0.039	1.643ProLys: 1.643 ± 0.036	4.991ProLeu: 4.991 ± 0.057	1.191ProMet: 1.191 ± 0.022	1.351ProAsn: 1.351 ± 0.029	2.681ProPro: 2.681 ± 0.046	1.738ProGln: 1.738 ± 0.035	3.248ProArg: 3.248 ± 0.051	2.978ProSer: 2.978 ± 0.047	2.564ProThr: 2.564 ± 0.039	4.231ProVal: 4.231 ± 0.051	0.693ProTrp: 0.693 ± 0.023	1.15ProTyr: 1.15 ± 0.027	0.0ProXaa: 0.0 ± 0.0
Gln	4.401GlnAla: 4.401 ± 0.059	0.159GlnCys: 0.159 ± 0.011	1.399GlnAsp: 1.399 ± 0.028	1.356GlnGlu: 1.356 ± 0.028	1.042GlnPhe: 1.042 ± 0.025	2.462GlnGly: 2.462 ± 0.045	0.573GlnHis: 0.573 ± 0.015	1.879GlnIle: 1.879 ± 0.03	0.931GlnLys: 0.931 ± 0.023	2.762GlnLeu: 2.762 ± 0.046	0.771GlnMet: 0.771 ± 0.018	0.855GlnAsn: 0.855 ± 0.025	1.846GlnPro: 1.846 ± 0.038	1.198GlnGln: 1.198 ± 0.04	2.568GlnArg: 2.568 ± 0.044	1.732GlnSer: 1.732 ± 0.033	1.609GlnThr: 1.609 ± 0.03	2.12GlnVal: 2.12 ± 0.037	0.345GlnTrp: 0.345 ± 0.015	0.541GlnTyr: 0.541 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	8.067ArgAla: 8.067 ± 0.079	0.52ArgCys: 0.52 ± 0.017	4.044ArgAsp: 4.044 ± 0.052	4.247ArgGlu: 4.247 ± 0.055	3.131ArgPhe: 3.131 ± 0.05	4.966ArgGly: 4.966 ± 0.055	1.649ArgHis: 1.649 ± 0.033	4.145ArgIle: 4.145 ± 0.052	2.235ArgLys: 2.235 ± 0.037	8.159ArgLeu: 8.159 ± 0.083	1.856ArgMet: 1.856 ± 0.029	1.802ArgAsn: 1.802 ± 0.033	3.749ArgPro: 3.749 ± 0.053	2.533ArgGln: 2.533 ± 0.046	5.671ArgArg: 5.671 ± 0.076	3.942ArgSer: 3.942 ± 0.051	3.244ArgThr: 3.244 ± 0.047	4.76ArgVal: 4.76 ± 0.063	0.987ArgTrp: 0.987 ± 0.025	1.647ArgTyr: 1.647 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	6.553SerAla: 6.553 ± 0.063	0.42SerCys: 0.42 ± 0.018	2.834SerAsp: 2.834 ± 0.046	2.795SerGlu: 2.795 ± 0.044	2.431SerPhe: 2.431 ± 0.044	5.772SerGly: 5.772 ± 0.077	1.067SerHis: 1.067 ± 0.023	2.774SerIle: 2.774 ± 0.048	1.52SerLys: 1.52 ± 0.032	5.859SerLeu: 5.859 ± 0.061	1.24SerMet: 1.24 ± 0.027	1.275SerAsn: 1.275 ± 0.029	2.876SerPro: 2.876 ± 0.047	1.677SerGln: 1.677 ± 0.032	3.823SerArg: 3.823 ± 0.056	2.98SerSer: 2.98 ± 0.051	2.692SerThr: 2.692 ± 0.042	4.017SerVal: 4.017 ± 0.048	0.853SerTrp: 0.853 ± 0.024	1.289SerTyr: 1.289 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	6.225ThrAla: 6.225 ± 0.062	0.407ThrCys: 0.407 ± 0.016	2.468ThrAsp: 2.468 ± 0.038	2.48ThrGlu: 2.48 ± 0.041	1.912ThrPhe: 1.912 ± 0.04	5.07ThrGly: 5.07 ± 0.069	0.979ThrHis: 0.979 ± 0.022	3.093ThrIle: 3.093 ± 0.047	1.494ThrLys: 1.494 ± 0.031	6.141ThrLeu: 6.141 ± 0.058	1.232ThrMet: 1.232 ± 0.026	1.223ThrAsn: 1.223 ± 0.028	3.248ThrPro: 3.248 ± 0.045	1.561ThrGln: 1.561 ± 0.033	3.357ThrArg: 3.357 ± 0.047	2.858ThrSer: 2.858 ± 0.043	2.916ThrThr: 2.916 ± 0.046	4.221ThrVal: 4.221 ± 0.047	0.595ThrTrp: 0.595 ± 0.019	1.081ThrTyr: 1.081 ± 0.025	0.0ThrXaa: 0.0 ± 0.0
Val	9.876ValAla: 9.876 ± 0.08	0.565ValCys: 0.565 ± 0.018	3.915ValAsp: 3.915 ± 0.049	4.487ValGlu: 4.487 ± 0.052	2.799ValPhe: 2.799 ± 0.047	5.76ValGly: 5.76 ± 0.066	1.253ValHis: 1.253 ± 0.026	4.053ValIle: 4.053 ± 0.046	2.343ValLys: 2.343 ± 0.04	7.609ValLeu: 7.609 ± 0.081	1.933ValMet: 1.933 ± 0.037	1.826ValAsn: 1.826 ± 0.032	3.803ValPro: 3.803 ± 0.045	1.97ValGln: 1.97 ± 0.034	4.676ValArg: 4.676 ± 0.054	4.501ValSer: 4.501 ± 0.05	4.645ValThr: 4.645 ± 0.053	6.15ValVal: 6.15 ± 0.061	0.812ValTrp: 0.812 ± 0.024	1.394ValTyr: 1.394 ± 0.026	0.0ValXaa: 0.0 ± 0.0
Trp	1.214TrpAla: 1.214 ± 0.032	0.133TrpCys: 0.133 ± 0.009	0.581TrpAsp: 0.581 ± 0.018	0.518TrpGlu: 0.518 ± 0.018	0.533TrpPhe: 0.533 ± 0.018	0.943TrpGly: 0.943 ± 0.022	0.313TrpHis: 0.313 ± 0.013	0.654TrpIle: 0.654 ± 0.02	0.424TrpLys: 0.424 ± 0.017	1.696TrpLeu: 1.696 ± 0.032	0.311TrpMet: 0.311 ± 0.014	0.419TrpAsn: 0.419 ± 0.017	0.737TrpPro: 0.737 ± 0.022	0.519TrpGln: 0.519 ± 0.018	1.202TrpArg: 1.202 ± 0.026	0.852TrpSer: 0.852 ± 0.023	0.749TrpThr: 0.749 ± 0.022	0.686TrpVal: 0.686 ± 0.023	0.235TrpTrp: 0.235 ± 0.012	0.266TrpTyr: 0.266 ± 0.013	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.521TyrAla: 2.521 ± 0.041	0.207TyrCys: 0.207 ± 0.01	1.309TyrAsp: 1.309 ± 0.03	1.13TyrGlu: 1.13 ± 0.027	0.786TyrPhe: 0.786 ± 0.023	2.111TyrGly: 2.111 ± 0.036	0.402TyrHis: 0.402 ± 0.016	0.848TyrIle: 0.848 ± 0.023	0.601TyrLys: 0.601 ± 0.019	2.144TyrLeu: 2.144 ± 0.041	0.375TyrMet: 0.375 ± 0.015	0.544TyrAsn: 0.544 ± 0.019	1.114TyrPro: 1.114 ± 0.025	0.618TyrGln: 0.618 ± 0.018	1.664TyrArg: 1.664 ± 0.031	1.044TyrSer: 1.044 ± 0.025	0.982TyrThr: 0.982 ± 0.025	1.526TyrVal: 1.526 ± 0.03	0.342TyrTrp: 0.342 ± 0.014	0.488TyrTyr: 0.488 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5472 proteins (1726800 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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