Amino acid dipepetide frequency for Paeniclostridium sordellii (strain ATCC 9714 / DSM 2141 / JCM 3814 / LMG 15708 / NCIMB 10717 / 211) (Clostridium sordellii)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.897AlaAla: 2.897 ± 0.075
0.742AlaCys: 0.742 ± 0.029
2.222AlaAsp: 2.222 ± 0.054
2.377AlaGlu: 2.377 ± 0.059
2.294AlaPhe: 2.294 ± 0.045
3.34AlaGly: 3.34 ± 0.084
0.793AlaHis: 0.793 ± 0.03
5.855AlaIle: 5.855 ± 0.091
4.696AlaLys: 4.696 ± 0.079
5.324AlaLeu: 5.324 ± 0.093
1.667AlaMet: 1.667 ± 0.043
2.851AlaAsn: 2.851 ± 0.052
1.26AlaPro: 1.26 ± 0.035
1.394AlaGln: 1.394 ± 0.039
1.679AlaArg: 1.679 ± 0.047
3.308AlaSer: 3.308 ± 0.123
2.782AlaThr: 2.782 ± 0.064
3.326AlaVal: 3.326 ± 0.066
0.29AlaTrp: 0.29 ± 0.017
1.999AlaTyr: 1.999 ± 0.047
0.0AlaXaa: 0.0 ± 0.0
Cys
0.586CysAla: 0.586 ± 0.028
0.194CysCys: 0.194 ± 0.02
0.698CysAsp: 0.698 ± 0.031
0.842CysGlu: 0.842 ± 0.032
0.504CysPhe: 0.504 ± 0.022
1.03CysGly: 1.03 ± 0.036
0.196CysHis: 0.196 ± 0.016
1.339CysIle: 1.339 ± 0.041
1.011CysLys: 1.011 ± 0.036
0.921CysLeu: 0.921 ± 0.034
0.353CysMet: 0.353 ± 0.02
0.722CysAsn: 0.722 ± 0.033
0.468CysPro: 0.468 ± 0.024
0.198CysGln: 0.198 ± 0.016
0.338CysArg: 0.338 ± 0.019
0.807CysSer: 0.807 ± 0.032
0.551CysThr: 0.551 ± 0.025
0.664CysVal: 0.664 ± 0.027
0.06CysTrp: 0.06 ± 0.008
0.405CysTyr: 0.405 ± 0.02
0.0CysXaa: 0.0 ± 0.0
Asp
2.489AspAla: 2.489 ± 0.057
0.608AspCys: 0.608 ± 0.029
2.804AspAsp: 2.804 ± 0.064
4.686AspGlu: 4.686 ± 0.077
2.691AspPhe: 2.691 ± 0.053
3.157AspGly: 3.157 ± 0.065
0.526AspHis: 0.526 ± 0.023
7.028AspIle: 7.028 ± 0.106
6.088AspLys: 6.088 ± 0.095
5.253AspLeu: 5.253 ± 0.078
1.739AspMet: 1.739 ± 0.048
3.354AspAsn: 3.354 ± 0.067
1.218AspPro: 1.218 ± 0.037
0.859AspGln: 0.859 ± 0.034
1.723AspArg: 1.723 ± 0.04
3.347AspSer: 3.347 ± 0.063
2.538AspThr: 2.538 ± 0.052
3.506AspVal: 3.506 ± 0.052
0.319AspTrp: 0.319 ± 0.02
2.734AspTyr: 2.734 ± 0.054
0.0AspXaa: 0.0 ± 0.0
Glu
3.477GluAla: 3.477 ± 0.064
0.713GluCys: 0.713 ± 0.031
4.352GluAsp: 4.352 ± 0.083
6.168GluGlu: 6.168 ± 0.091
2.982GluPhe: 2.982 ± 0.06
3.696GluGly: 3.696 ± 0.062
0.91GluHis: 0.91 ± 0.029
6.992GluIle: 6.992 ± 0.093
7.303GluLys: 7.303 ± 0.114
6.448GluLeu: 6.448 ± 0.099
1.802GluMet: 1.802 ± 0.044
5.743GluAsn: 5.743 ± 0.089
1.234GluPro: 1.234 ± 0.041
1.511GluGln: 1.511 ± 0.046
2.093GluArg: 2.093 ± 0.055
3.716GluSer: 3.716 ± 0.067
2.756GluThr: 2.756 ± 0.062
4.829GluVal: 4.829 ± 0.09
0.324GluTrp: 0.324 ± 0.019
3.08GluTyr: 3.08 ± 0.06
0.0GluXaa: 0.0 ± 0.0
Phe
2.218PheAla: 2.218 ± 0.054
0.48PheCys: 0.48 ± 0.023
2.535PheAsp: 2.535 ± 0.061
2.89PheGlu: 2.89 ± 0.067
1.804PhePhe: 1.804 ± 0.051
2.74PheGly: 2.74 ± 0.061
0.468PheHis: 0.468 ± 0.027
5.206PheIle: 5.206 ± 0.081
3.9PheLys: 3.9 ± 0.066
3.993PheLeu: 3.993 ± 0.077
1.439PheMet: 1.439 ± 0.044
2.993PheAsn: 2.993 ± 0.069
0.961PhePro: 0.961 ± 0.036
0.766PheGln: 0.766 ± 0.029
1.109PheArg: 1.109 ± 0.034
2.896PheSer: 2.896 ± 0.055
2.247PheThr: 2.247 ± 0.058
2.668PheVal: 2.668 ± 0.055
0.261PheTrp: 0.261 ± 0.016
1.707PheTyr: 1.707 ± 0.047
0.0PheXaa: 0.0 ± 0.0
Gly
3.881GlyAla: 3.881 ± 0.075
1.001GlyCys: 1.001 ± 0.034
3.027GlyAsp: 3.027 ± 0.059
3.689GlyGlu: 3.689 ± 0.068
3.06GlyPhe: 3.06 ± 0.061
4.039GlyGly: 4.039 ± 0.079
1.01GlyHis: 1.01 ± 0.04
6.631GlyIle: 6.631 ± 0.102
5.084GlyLys: 5.084 ± 0.076
5.411GlyLeu: 5.411 ± 0.08
1.85GlyMet: 1.85 ± 0.046
3.214GlyAsn: 3.214 ± 0.067
1.281GlyPro: 1.281 ± 0.04
1.45GlyGln: 1.45 ± 0.038
1.87GlyArg: 1.87 ± 0.048
3.63GlySer: 3.63 ± 0.069
3.066GlyThr: 3.066 ± 0.063
4.71GlyVal: 4.71 ± 0.078
0.423GlyTrp: 0.423 ± 0.022
3.119GlyTyr: 3.119 ± 0.067
0.0GlyXaa: 0.0 ± 0.0
His
0.65HisAla: 0.65 ± 0.028
0.198HisCys: 0.198 ± 0.017
0.645HisAsp: 0.645 ± 0.025
0.865HisGlu: 0.865 ± 0.03
0.581HisPhe: 0.581 ± 0.025
0.924HisGly: 0.924 ± 0.034
0.265HisHis: 0.265 ± 0.016
1.396HisIle: 1.396 ± 0.038
1.155HisLys: 1.155 ± 0.034
1.287HisLeu: 1.287 ± 0.039
0.462HisMet: 0.462 ± 0.022
0.782HisAsn: 0.782 ± 0.031
0.525HisPro: 0.525 ± 0.026
0.355HisGln: 0.355 ± 0.019
0.442HisArg: 0.442 ± 0.027
0.82HisSer: 0.82 ± 0.03
0.689HisThr: 0.689 ± 0.027
0.737HisVal: 0.737 ± 0.027
0.108HisTrp: 0.108 ± 0.012
0.54HisTyr: 0.54 ± 0.025
0.0HisXaa: 0.0 ± 0.0
Ile
5.628IleAla: 5.628 ± 0.089
1.44IleCys: 1.44 ± 0.04
6.65IleAsp: 6.65 ± 0.095
7.23IleGlu: 7.23 ± 0.095
4.321IlePhe: 4.321 ± 0.087
6.63IleGly: 6.63 ± 0.105
1.331IleHis: 1.331 ± 0.038
9.958IleIle: 9.958 ± 0.122
9.803IleLys: 9.803 ± 0.113
9.686IleLeu: 9.686 ± 0.118
2.987IleMet: 2.987 ± 0.056
7.068IleAsn: 7.068 ± 0.115
3.319IlePro: 3.319 ± 0.057
2.397IleGln: 2.397 ± 0.054
2.745IleArg: 2.745 ± 0.06
7.412IleSer: 7.412 ± 0.09
4.973IleThr: 4.973 ± 0.081
6.726IleVal: 6.726 ± 0.083
0.56IleTrp: 0.56 ± 0.025
4.135IleTyr: 4.135 ± 0.085
0.0IleXaa: 0.0 ± 0.0
Lys
4.348LysAla: 4.348 ± 0.069
0.88LysCys: 0.88 ± 0.036
6.594LysAsp: 6.594 ± 0.09
8.721LysGlu: 8.721 ± 0.119
3.803LysPhe: 3.803 ± 0.065
4.704LysGly: 4.704 ± 0.075
1.254LysHis: 1.254 ± 0.035
8.592LysIle: 8.592 ± 0.097
8.554LysLys: 8.554 ± 0.116
8.282LysLeu: 8.282 ± 0.107
2.933LysMet: 2.933 ± 0.056
7.405LysAsn: 7.405 ± 0.106
2.149LysPro: 2.149 ± 0.059
2.242LysGln: 2.242 ± 0.053
2.694LysArg: 2.694 ± 0.055
5.885LysSer: 5.885 ± 0.082
4.186LysThr: 4.186 ± 0.067
6.077LysVal: 6.077 ± 0.091
0.572LysTrp: 0.572 ± 0.027
4.421LysTyr: 4.421 ± 0.082
0.0LysXaa: 0.0 ± 0.0
Leu
4.96LeuAla: 4.96 ± 0.088
0.981LeuCys: 0.981 ± 0.037
5.576LeuAsp: 5.576 ± 0.071
6.394LeuGlu: 6.394 ± 0.092
3.678LeuPhe: 3.678 ± 0.065
6.276LeuGly: 6.276 ± 0.09
1.062LeuHis: 1.062 ± 0.036
8.757LeuIle: 8.757 ± 0.12
8.8LeuLys: 8.8 ± 0.112
7.632LeuLeu: 7.632 ± 0.11
3.023LeuMet: 3.023 ± 0.053
6.629LeuAsn: 6.629 ± 0.093
2.515LeuPro: 2.515 ± 0.058
1.894LeuGln: 1.894 ± 0.039
2.796LeuArg: 2.796 ± 0.061
6.59LeuSer: 6.59 ± 0.091
4.36LeuThr: 4.36 ± 0.074
5.984LeuVal: 5.984 ± 0.081
0.546LeuTrp: 0.546 ± 0.021
3.338LeuTyr: 3.338 ± 0.069
0.0LeuXaa: 0.0 ± 0.0
Met
1.876MetAla: 1.876 ± 0.054
0.33MetCys: 0.33 ± 0.021
1.779MetAsp: 1.779 ± 0.038
1.946MetGlu: 1.946 ± 0.043
1.199MetPhe: 1.199 ± 0.035
2.047MetGly: 2.047 ± 0.049
0.408MetHis: 0.408 ± 0.021
2.856MetIle: 2.856 ± 0.056
3.008MetLys: 3.008 ± 0.065
2.645MetLeu: 2.645 ± 0.055
0.925MetMet: 0.925 ± 0.031
2.042MetAsn: 2.042 ± 0.05
0.99MetPro: 0.99 ± 0.035
0.772MetGln: 0.772 ± 0.03
0.872MetArg: 0.872 ± 0.033
1.939MetSer: 1.939 ± 0.045
1.384MetThr: 1.384 ± 0.041
1.873MetVal: 1.873 ± 0.054
0.148MetTrp: 0.148 ± 0.013
1.127MetTyr: 1.127 ± 0.041
0.0MetXaa: 0.0 ± 0.0
Asn
2.607AsnAla: 2.607 ± 0.052
0.732AsnCys: 0.732 ± 0.032
3.221AsnAsp: 3.221 ± 0.063
4.649AsnGlu: 4.649 ± 0.073
2.744AsnPhe: 2.744 ± 0.054
3.438AsnGly: 3.438 ± 0.066
0.931AsnHis: 0.931 ± 0.033
8.16AsnIle: 8.16 ± 0.112
7.127AsnLys: 7.127 ± 0.091
6.736AsnLeu: 6.736 ± 0.096
2.049AsnMet: 2.049 ± 0.052
4.811AsnAsn: 4.811 ± 0.079
2.193AsnPro: 2.193 ± 0.053
1.818AsnGln: 1.818 ± 0.043
1.852AsnArg: 1.852 ± 0.047
3.967AsnSer: 3.967 ± 0.065
3.073AsnThr: 3.073 ± 0.058
3.5AsnVal: 3.5 ± 0.063
0.387AsnTrp: 0.387 ± 0.022
2.904AsnTyr: 2.904 ± 0.061
0.0AsnXaa: 0.0 ± 0.0
Pro
1.283ProAla: 1.283 ± 0.043
0.298ProCys: 0.298 ± 0.017
1.306ProAsp: 1.306 ± 0.04
1.785ProGlu: 1.785 ± 0.042
1.245ProPhe: 1.245 ± 0.04
1.609ProGly: 1.609 ± 0.049
0.436ProHis: 0.436 ± 0.02
2.933ProIle: 2.933 ± 0.06
2.381ProLys: 2.381 ± 0.05
2.23ProLeu: 2.23 ± 0.05
0.813ProMet: 0.813 ± 0.032
1.586ProAsn: 1.586 ± 0.036
0.538ProPro: 0.538 ± 0.033
0.753ProGln: 0.753 ± 0.029
0.731ProArg: 0.731 ± 0.028
1.744ProSer: 1.744 ± 0.045
1.52ProThr: 1.52 ± 0.048
1.891ProVal: 1.891 ± 0.047
0.208ProTrp: 0.208 ± 0.015
1.19ProTyr: 1.19 ± 0.043
0.0ProXaa: 0.0 ± 0.0
Gln
1.27GlnAla: 1.27 ± 0.038
0.25GlnCys: 0.25 ± 0.02
1.193GlnAsp: 1.193 ± 0.037
1.666GlnGlu: 1.666 ± 0.043
0.886GlnPhe: 0.886 ± 0.03
1.491GlnGly: 1.491 ± 0.044
0.301GlnHis: 0.301 ± 0.018
2.339GlnIle: 2.339 ± 0.05
2.101GlnLys: 2.101 ± 0.048
2.048GlnLeu: 2.048 ± 0.046
0.839GlnMet: 0.839 ± 0.031
1.55GlnAsn: 1.55 ± 0.044
0.63GlnPro: 0.63 ± 0.03
0.707GlnGln: 0.707 ± 0.035
0.907GlnArg: 0.907 ± 0.037
1.395GlnSer: 1.395 ± 0.039
1.105GlnThr: 1.105 ± 0.037
1.604GlnVal: 1.604 ± 0.046
0.148GlnTrp: 0.148 ± 0.012
0.943GlnTyr: 0.943 ± 0.031
0.0GlnXaa: 0.0 ± 0.0
Arg
1.555ArgAla: 1.555 ± 0.046
0.407ArgCys: 0.407 ± 0.023
1.699ArgAsp: 1.699 ± 0.045
2.33ArgGlu: 2.33 ± 0.053
1.27ArgPhe: 1.27 ± 0.039
1.753ArgGly: 1.753 ± 0.042
0.449ArgHis: 0.449 ± 0.022
2.622ArgIle: 2.622 ± 0.053
2.817ArgLys: 2.817 ± 0.06
2.688ArgLeu: 2.688 ± 0.058
0.841ArgMet: 0.841 ± 0.032
1.904ArgAsn: 1.904 ± 0.042
0.775ArgPro: 0.775 ± 0.032
0.823ArgGln: 0.823 ± 0.029
1.162ArgArg: 1.162 ± 0.038
1.463ArgSer: 1.463 ± 0.041
1.327ArgThr: 1.327 ± 0.037
2.089ArgVal: 2.089 ± 0.047
0.201ArgTrp: 0.201 ± 0.016
1.451ArgTyr: 1.451 ± 0.038
0.0ArgXaa: 0.0 ± 0.0
Ser
3.011SerAla: 3.011 ± 0.115
0.681SerCys: 0.681 ± 0.028
3.187SerAsp: 3.187 ± 0.064
3.809SerGlu: 3.809 ± 0.082
2.931SerPhe: 2.931 ± 0.064
3.991SerGly: 3.991 ± 0.082
0.83SerHis: 0.83 ± 0.032
7.399SerIle: 7.399 ± 0.093
6.391SerLys: 6.391 ± 0.1
6.014SerLeu: 6.014 ± 0.087
1.817SerMet: 1.817 ± 0.046
4.162SerAsn: 4.162 ± 0.074
1.595SerPro: 1.595 ± 0.042
1.823SerGln: 1.823 ± 0.039
1.921SerArg: 1.921 ± 0.044
4.397SerSer: 4.397 ± 0.091
3.178SerThr: 3.178 ± 0.065
3.715SerVal: 3.715 ± 0.064
0.364SerTrp: 0.364 ± 0.021
2.676SerTyr: 2.676 ± 0.059
0.0SerXaa: 0.0 ± 0.0
Thr
2.53ThrAla: 2.53 ± 0.057
0.501ThrCys: 0.501 ± 0.025
2.365ThrAsp: 2.365 ± 0.05
2.409ThrGlu: 2.409 ± 0.048
2.063ThrPhe: 2.063 ± 0.05
3.365ThrGly: 3.365 ± 0.061
0.765ThrHis: 0.765 ± 0.026
5.275ThrIle: 5.275 ± 0.084
3.935ThrLys: 3.935 ± 0.059
4.674ThrLeu: 4.674 ± 0.075
1.337ThrMet: 1.337 ± 0.04
2.889ThrAsn: 2.889 ± 0.055
1.725ThrPro: 1.725 ± 0.04
1.199ThrGln: 1.199 ± 0.038
1.366ThrArg: 1.366 ± 0.039
3.202ThrSer: 3.202 ± 0.065
2.7ThrThr: 2.7 ± 0.06
3.302ThrVal: 3.302 ± 0.07
0.317ThrTrp: 0.317 ± 0.02
1.999ThrTyr: 1.999 ± 0.045
0.0ThrXaa: 0.0 ± 0.0
Val
3.728ValAla: 3.728 ± 0.073
0.915ValCys: 0.915 ± 0.029
4.04ValAsp: 4.04 ± 0.078
4.343ValGlu: 4.343 ± 0.071
2.966ValPhe: 2.966 ± 0.056
4.398ValGly: 4.398 ± 0.079
0.821ValHis: 0.821 ± 0.034
6.164ValIle: 6.164 ± 0.103
5.445ValLys: 5.445 ± 0.076
6.033ValLeu: 6.033 ± 0.091
1.73ValMet: 1.73 ± 0.044
3.932ValAsn: 3.932 ± 0.066
1.777ValPro: 1.777 ± 0.044
1.322ValGln: 1.322 ± 0.037
1.857ValArg: 1.857 ± 0.043
4.369ValSer: 4.369 ± 0.068
3.136ValThr: 3.136 ± 0.059
4.598ValVal: 4.598 ± 0.078
0.367ValTrp: 0.367 ± 0.019
2.497ValTyr: 2.497 ± 0.049
0.0ValXaa: 0.0 ± 0.0
Trp
0.334TrpAla: 0.334 ± 0.021
0.069TrpCys: 0.069 ± 0.009
0.395TrpAsp: 0.395 ± 0.02
0.382TrpGlu: 0.382 ± 0.019
0.264TrpPhe: 0.264 ± 0.018
0.4TrpGly: 0.4 ± 0.022
0.101TrpHis: 0.101 ± 0.011
0.62TrpIle: 0.62 ± 0.026
0.417TrpLys: 0.417 ± 0.02
0.525TrpLeu: 0.525 ± 0.023
0.205TrpMet: 0.205 ± 0.017
0.385TrpAsn: 0.385 ± 0.02
0.126TrpPro: 0.126 ± 0.012
0.163TrpGln: 0.163 ± 0.013
0.194TrpArg: 0.194 ± 0.015
0.323TrpSer: 0.323 ± 0.02
0.279TrpThr: 0.279 ± 0.018
0.425TrpVal: 0.425 ± 0.02
0.07TrpTrp: 0.07 ± 0.01
0.279TrpTyr: 0.279 ± 0.018
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.771TyrAla: 1.771 ± 0.05
0.467TyrCys: 0.467 ± 0.022
2.379TyrAsp: 2.379 ± 0.051
2.951TyrGlu: 2.951 ± 0.063
1.994TyrPhe: 1.994 ± 0.063
2.42TyrGly: 2.42 ± 0.055
0.57TyrHis: 0.57 ± 0.027
4.873TyrIle: 4.873 ± 0.088
4.279TyrLys: 4.279 ± 0.074
3.957TyrLeu: 3.957 ± 0.066
1.35TyrMet: 1.35 ± 0.043
2.88TyrAsn: 2.88 ± 0.059
1.2TyrPro: 1.2 ± 0.034
0.929TyrGln: 0.929 ± 0.033
1.275TyrArg: 1.275 ± 0.038
2.68TyrSer: 2.68 ± 0.057
2.068TyrThr: 2.068 ± 0.05
2.219TyrVal: 2.219 ± 0.052
0.281TyrTrp: 0.281 ± 0.018
1.696TyrTyr: 1.696 ± 0.049
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5956 proteins (904124 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski