Amino acid dipepetide frequency for Wuhan insect virus 20

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.72AlaAla: 5.72 ± 3.337
0.953AlaCys: 0.953 ± 0.7
2.86AlaAsp: 2.86 ± 1.738
3.813AlaGlu: 3.813 ± 0.749
5.72AlaPhe: 5.72 ± 0.82
4.766AlaGly: 4.766 ± 2.323
0.0AlaHis: 0.0 ± 0.0
3.813AlaIle: 3.813 ± 1.566
2.86AlaLys: 2.86 ± 2.099
6.673AlaLeu: 6.673 ± 2.837
0.953AlaMet: 0.953 ± 0.7
2.86AlaAsn: 2.86 ± 0.313
0.953AlaPro: 0.953 ± 0.709
1.907AlaGln: 1.907 ± 1.418
1.907AlaArg: 1.907 ± 0.964
2.86AlaSer: 2.86 ± 0.313
4.766AlaThr: 4.766 ± 1.416
8.58AlaVal: 8.58 ± 1.845
0.953AlaTrp: 0.953 ± 0.909
1.907AlaTyr: 1.907 ± 0.61
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
1.907CysGlu: 1.907 ± 0.61
0.0CysPhe: 0.0 ± 0.0
1.907CysGly: 1.907 ± 1.418
0.953CysHis: 0.953 ± 0.909
1.907CysIle: 1.907 ± 0.783
0.953CysLys: 0.953 ± 0.709
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.593
0.953CysAsn: 0.953 ± 0.709
0.953CysPro: 0.953 ± 0.709
0.953CysGln: 0.953 ± 0.709
0.0CysArg: 0.0 ± 0.0
2.86CysSer: 2.86 ± 2.099
0.0CysThr: 0.0 ± 0.0
1.907CysVal: 1.907 ± 0.61
0.953CysTrp: 0.953 ± 0.7
1.907CysTyr: 1.907 ± 1.399
0.0CysXaa: 0.0 ± 0.0
Asp
4.766AspAla: 4.766 ± 1.662
0.953AspCys: 0.953 ± 0.709
2.86AspAsp: 2.86 ± 0.313
7.626AspGlu: 7.626 ± 1.204
0.953AspPhe: 0.953 ± 0.7
1.907AspGly: 1.907 ± 0.783
0.953AspHis: 0.953 ± 0.7
1.907AspIle: 1.907 ± 0.783
1.907AspLys: 1.907 ± 0.61
6.673AspLeu: 6.673 ± 3.795
0.953AspMet: 0.953 ± 0.909
3.813AspAsn: 3.813 ± 1.566
2.86AspPro: 2.86 ± 1.186
2.86AspGln: 2.86 ± 1.105
3.813AspArg: 3.813 ± 1.214
4.766AspSer: 4.766 ± 1.204
1.907AspThr: 1.907 ± 0.61
3.813AspVal: 3.813 ± 1.214
1.907AspTrp: 1.907 ± 0.783
0.953AspTyr: 0.953 ± 0.909
0.0AspXaa: 0.0 ± 0.0
Glu
2.86GluAla: 2.86 ± 0.313
0.0GluCys: 0.0 ± 0.0
4.766GluAsp: 4.766 ± 0.966
6.673GluGlu: 6.673 ± 3.795
1.907GluPhe: 1.907 ± 0.61
0.953GluGly: 0.953 ± 0.909
0.953GluHis: 0.953 ± 0.709
2.86GluIle: 2.86 ± 1.541
3.813GluLys: 3.813 ± 1.79
7.626GluLeu: 7.626 ± 2.769
0.953GluMet: 0.953 ± 0.7
3.813GluAsn: 3.813 ± 0.749
3.813GluPro: 3.813 ± 1.775
4.766GluGln: 4.766 ± 1.642
10.486GluArg: 10.486 ± 0.433
3.813GluSer: 3.813 ± 0.749
1.907GluThr: 1.907 ± 1.399
3.813GluVal: 3.813 ± 1.928
0.0GluTrp: 0.0 ± 0.0
0.953GluTyr: 0.953 ± 0.7
0.0GluXaa: 0.0 ± 0.0
Phe
0.953PheAla: 0.953 ± 0.7
2.86PheCys: 2.86 ± 1.122
4.766PheAsp: 4.766 ± 1.662
0.953PheGlu: 0.953 ± 0.7
0.953PhePhe: 0.953 ± 0.909
4.766PheGly: 4.766 ± 1.662
2.86PheHis: 2.86 ± 1.186
0.953PheIle: 0.953 ± 0.7
1.907PheLys: 1.907 ± 0.783
5.72PheLeu: 5.72 ± 0.82
3.813PheMet: 3.813 ± 1.248
5.72PheAsn: 5.72 ± 2.372
0.953PhePro: 0.953 ± 0.909
0.953PheGln: 0.953 ± 0.7
0.953PheArg: 0.953 ± 0.909
0.953PheSer: 0.953 ± 0.7
0.0PheThr: 0.0 ± 0.0
1.907PheVal: 1.907 ± 0.61
0.0PheTrp: 0.0 ± 0.0
1.907PheTyr: 1.907 ± 1.817
0.0PheXaa: 0.0 ± 0.0
Gly
1.907GlyAla: 1.907 ± 0.964
0.953GlyCys: 0.953 ± 0.7
3.813GlyAsp: 3.813 ± 1.566
1.907GlyGlu: 1.907 ± 0.964
3.813GlyPhe: 3.813 ± 0.749
0.953GlyGly: 0.953 ± 0.709
1.907GlyHis: 1.907 ± 0.783
0.953GlyIle: 0.953 ± 0.709
4.766GlyLys: 4.766 ± 1.204
1.907GlyLeu: 1.907 ± 0.783
2.86GlyMet: 2.86 ± 1.186
0.953GlyAsn: 0.953 ± 0.709
1.907GlyPro: 1.907 ± 0.964
0.0GlyGln: 0.0 ± 0.0
2.86GlyArg: 2.86 ± 0.313
7.626GlySer: 7.626 ± 2.429
3.813GlyThr: 3.813 ± 1.22
4.766GlyVal: 4.766 ± 2.451
0.0GlyTrp: 0.0 ± 0.0
4.766GlyTyr: 4.766 ± 0.966
0.0GlyXaa: 0.0 ± 0.0
His
1.907HisAla: 1.907 ± 0.61
0.0HisCys: 0.0 ± 0.0
0.953HisAsp: 0.953 ± 0.709
0.953HisGlu: 0.953 ± 0.909
0.953HisPhe: 0.953 ± 0.909
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
1.907HisLys: 1.907 ± 0.783
0.0HisLeu: 0.0 ± 0.0
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
1.907HisPro: 1.907 ± 0.783
0.953HisGln: 0.953 ± 0.7
3.813HisArg: 3.813 ± 1.566
2.86HisSer: 2.86 ± 1.122
0.0HisThr: 0.0 ± 0.0
2.86HisVal: 2.86 ± 1.541
0.953HisTrp: 0.953 ± 0.709
0.953HisTyr: 0.953 ± 0.7
0.0HisXaa: 0.0 ± 0.0
Ile
0.953IleAla: 0.953 ± 0.709
3.813IleCys: 3.813 ± 1.22
2.86IleAsp: 2.86 ± 1.186
3.813IleGlu: 3.813 ± 1.566
0.0IlePhe: 0.0 ± 0.0
2.86IleGly: 2.86 ± 1.541
0.953IleHis: 0.953 ± 0.909
1.907IleIle: 1.907 ± 1.418
3.813IleLys: 3.813 ± 1.22
1.907IleLeu: 1.907 ± 0.61
0.953IleMet: 0.953 ± 0.709
0.953IleAsn: 0.953 ± 0.709
3.813IlePro: 3.813 ± 0.749
1.907IleGln: 1.907 ± 0.964
2.86IleArg: 2.86 ± 2.099
7.626IleSer: 7.626 ± 1.041
0.953IleThr: 0.953 ± 0.909
2.86IleVal: 2.86 ± 0.313
0.0IleTrp: 0.0 ± 0.0
1.907IleTyr: 1.907 ± 0.61
0.0IleXaa: 0.0 ± 0.0
Lys
6.673LysAla: 6.673 ± 0.485
0.0LysCys: 0.0 ± 0.0
5.72LysAsp: 5.72 ± 1.83
2.86LysGlu: 2.86 ± 2.099
7.626LysPhe: 7.626 ± 2.192
1.907LysGly: 1.907 ± 0.783
0.953LysHis: 0.953 ± 0.709
5.72LysIle: 5.72 ± 1.182
10.486LysLys: 10.486 ± 3.268
4.766LysLeu: 4.766 ± 0.339
0.953LysMet: 0.953 ± 0.709
0.953LysAsn: 0.953 ± 0.7
3.813LysPro: 3.813 ± 1.214
3.813LysGln: 3.813 ± 1.928
2.86LysArg: 2.86 ± 1.122
3.813LysSer: 3.813 ± 1.775
1.907LysThr: 1.907 ± 0.964
6.673LysVal: 6.673 ± 0.936
2.86LysTrp: 2.86 ± 1.122
3.813LysTyr: 3.813 ± 1.566
0.0LysXaa: 0.0 ± 0.0
Leu
5.72LeuAla: 5.72 ± 2.21
1.907LeuCys: 1.907 ± 0.61
4.766LeuAsp: 4.766 ± 1.246
2.86LeuGlu: 2.86 ± 1.186
0.953LeuPhe: 0.953 ± 0.709
3.813LeuGly: 3.813 ± 1.79
0.953LeuHis: 0.953 ± 0.909
3.813LeuIle: 3.813 ± 0.521
10.486LeuLys: 10.486 ± 2.152
5.72LeuLeu: 5.72 ± 1.83
2.86LeuMet: 2.86 ± 2.099
6.673LeuAsn: 6.673 ± 1.495
2.86LeuPro: 2.86 ± 2.099
3.813LeuGln: 3.813 ± 1.746
3.813LeuArg: 3.813 ± 0.521
5.72LeuSer: 5.72 ± 1.83
3.813LeuThr: 3.813 ± 1.22
4.766LeuVal: 4.766 ± 2.27
0.953LeuTrp: 0.953 ± 0.7
0.953LeuTyr: 0.953 ± 0.7
0.0LeuXaa: 0.0 ± 0.0
Met
1.907MetAla: 1.907 ± 1.399
1.907MetCys: 1.907 ± 1.418
0.953MetAsp: 0.953 ± 0.7
4.766MetGlu: 4.766 ± 1.204
0.953MetPhe: 0.953 ± 0.7
0.953MetGly: 0.953 ± 0.709
1.907MetHis: 1.907 ± 1.418
2.86MetIle: 2.86 ± 1.738
0.953MetLys: 0.953 ± 0.709
0.953MetLeu: 0.953 ± 0.709
0.953MetMet: 0.953 ± 0.709
0.0MetAsn: 0.0 ± 0.0
1.907MetPro: 1.907 ± 0.964
0.953MetGln: 0.953 ± 0.709
0.953MetArg: 0.953 ± 0.7
1.907MetSer: 1.907 ± 1.418
1.907MetThr: 1.907 ± 0.964
1.907MetVal: 1.907 ± 1.418
0.0MetTrp: 0.0 ± 0.0
0.953MetTyr: 0.953 ± 0.709
0.0MetXaa: 0.0 ± 0.0
Asn
2.86AsnAla: 2.86 ± 2.726
1.907AsnCys: 1.907 ± 0.964
0.953AsnAsp: 0.953 ± 0.709
1.907AsnGlu: 1.907 ± 1.418
3.813AsnPhe: 3.813 ± 0.521
0.953AsnGly: 0.953 ± 0.709
0.0AsnHis: 0.0 ± 0.0
1.907AsnIle: 1.907 ± 0.61
4.766AsnLys: 4.766 ± 0.339
2.86AsnLeu: 2.86 ± 1.186
0.953AsnMet: 0.953 ± 0.709
2.86AsnAsn: 2.86 ± 1.541
0.0AsnPro: 0.0 ± 0.0
0.953AsnGln: 0.953 ± 0.909
1.907AsnArg: 1.907 ± 0.61
2.86AsnSer: 2.86 ± 0.313
2.86AsnThr: 2.86 ± 2.126
4.766AsnVal: 4.766 ± 0.966
0.953AsnTrp: 0.953 ± 0.7
1.907AsnTyr: 1.907 ± 0.783
0.0AsnXaa: 0.0 ± 0.0
Pro
3.813ProAla: 3.813 ± 1.928
0.0ProCys: 0.0 ± 0.0
1.907ProAsp: 1.907 ± 0.783
2.86ProGlu: 2.86 ± 1.105
1.907ProPhe: 1.907 ± 0.61
2.86ProGly: 2.86 ± 1.419
0.953ProHis: 0.953 ± 0.909
0.953ProIle: 0.953 ± 0.709
0.953ProLys: 0.953 ± 0.7
1.907ProLeu: 1.907 ± 1.399
1.907ProMet: 1.907 ± 0.964
0.953ProAsn: 0.953 ± 0.709
0.953ProPro: 0.953 ± 0.7
0.953ProGln: 0.953 ± 0.709
2.86ProArg: 2.86 ± 2.126
1.907ProSer: 1.907 ± 0.964
6.673ProThr: 6.673 ± 2.206
9.533ProVal: 9.533 ± 1.926
0.0ProTrp: 0.0 ± 0.0
0.953ProTyr: 0.953 ± 0.909
0.0ProXaa: 0.0 ± 0.0
Gln
3.813GlnAla: 3.813 ± 1.746
1.907GlnCys: 1.907 ± 0.783
0.953GlnAsp: 0.953 ± 0.709
2.86GlnGlu: 2.86 ± 1.105
0.0GlnPhe: 0.0 ± 0.0
1.907GlnGly: 1.907 ± 1.399
1.907GlnHis: 1.907 ± 1.418
2.86GlnIle: 2.86 ± 2.099
1.907GlnLys: 1.907 ± 0.783
2.86GlnLeu: 2.86 ± 0.313
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
1.907GlnPro: 1.907 ± 0.964
0.953GlnGln: 0.953 ± 0.7
2.86GlnArg: 2.86 ± 1.419
3.813GlnSer: 3.813 ± 1.566
0.953GlnThr: 0.953 ± 0.909
1.907GlnVal: 1.907 ± 0.964
0.0GlnTrp: 0.0 ± 0.0
1.907GlnTyr: 1.907 ± 0.61
0.0GlnXaa: 0.0 ± 0.0
Arg
0.953ArgAla: 0.953 ± 0.7
0.0ArgCys: 0.0 ± 0.0
3.813ArgAsp: 3.813 ± 1.928
3.813ArgGlu: 3.813 ± 1.746
2.86ArgPhe: 2.86 ± 1.186
3.813ArgGly: 3.813 ± 0.521
1.907ArgHis: 1.907 ± 0.964
0.953ArgIle: 0.953 ± 0.7
4.766ArgLys: 4.766 ± 0.339
7.626ArgLeu: 7.626 ± 1.041
4.766ArgMet: 4.766 ± 1.383
0.953ArgAsn: 0.953 ± 0.7
2.86ArgPro: 2.86 ± 1.122
1.907ArgGln: 1.907 ± 0.964
6.673ArgArg: 6.673 ± 0.936
6.673ArgSer: 6.673 ± 1.731
0.953ArgThr: 0.953 ± 0.709
0.953ArgVal: 0.953 ± 0.7
1.907ArgTrp: 1.907 ± 0.61
3.813ArgTyr: 3.813 ± 0.521
0.0ArgXaa: 0.0 ± 0.0
Ser
5.72SerAla: 5.72 ± 0.626
0.0SerCys: 0.0 ± 0.0
6.673SerAsp: 6.673 ± 0.911
1.907SerGlu: 1.907 ± 0.783
2.86SerPhe: 2.86 ± 0.313
7.626SerGly: 7.626 ± 3.045
1.907SerHis: 1.907 ± 0.61
3.813SerIle: 3.813 ± 1.775
5.72SerLys: 5.72 ± 1.802
11.439SerLeu: 11.439 ± 2.671
3.813SerMet: 3.813 ± 1.79
0.0SerAsn: 0.0 ± 0.0
3.813SerPro: 3.813 ± 1.746
0.953SerGln: 0.953 ± 0.7
3.813SerArg: 3.813 ± 1.775
13.346SerSer: 13.346 ± 6.43
2.86SerThr: 2.86 ± 1.738
5.72SerVal: 5.72 ± 1.616
1.907SerTrp: 1.907 ± 0.783
3.813SerTyr: 3.813 ± 1.79
0.0SerXaa: 0.0 ± 0.0
Thr
5.72ThrAla: 5.72 ± 2.21
0.0ThrCys: 0.0 ± 0.0
2.86ThrAsp: 2.86 ± 1.541
1.907ThrGlu: 1.907 ± 0.783
0.953ThrPhe: 0.953 ± 0.7
1.907ThrGly: 1.907 ± 0.964
0.953ThrHis: 0.953 ± 0.909
2.86ThrIle: 2.86 ± 2.099
3.813ThrLys: 3.813 ± 1.22
0.953ThrLeu: 0.953 ± 0.7
0.953ThrMet: 0.953 ± 0.709
1.907ThrAsn: 1.907 ± 0.783
2.86ThrPro: 2.86 ± 0.313
2.86ThrGln: 2.86 ± 1.541
1.907ThrArg: 1.907 ± 0.61
2.86ThrSer: 2.86 ± 1.541
4.766ThrThr: 4.766 ± 3.487
2.86ThrVal: 2.86 ± 1.105
0.0ThrTrp: 0.0 ± 0.0
0.953ThrTyr: 0.953 ± 0.709
0.0ThrXaa: 0.0 ± 0.0
Val
4.766ValAla: 4.766 ± 2.122
0.953ValCys: 0.953 ± 0.709
2.86ValAsp: 2.86 ± 1.105
8.58ValGlu: 8.58 ± 1.543
4.766ValPhe: 4.766 ± 0.966
3.813ValGly: 3.813 ± 1.566
0.953ValHis: 0.953 ± 0.7
2.86ValIle: 2.86 ± 1.122
8.58ValLys: 8.58 ± 0.939
5.72ValLeu: 5.72 ± 2.245
0.0ValMet: 0.0 ± 0.0
1.907ValAsn: 1.907 ± 0.964
5.72ValPro: 5.72 ± 1.616
0.953ValGln: 0.953 ± 0.7
5.72ValArg: 5.72 ± 1.616
7.626ValSer: 7.626 ± 1.204
2.86ValThr: 2.86 ± 2.126
0.953ValVal: 0.953 ± 0.909
0.953ValTrp: 0.953 ± 0.909
3.813ValTyr: 3.813 ± 0.749
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
1.907TrpAsp: 1.907 ± 0.61
0.953TrpGlu: 0.953 ± 0.709
1.907TrpPhe: 1.907 ± 0.61
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.953TrpIle: 0.953 ± 0.7
1.907TrpLys: 1.907 ± 0.783
0.953TrpLeu: 0.953 ± 0.7
0.953TrpMet: 0.953 ± 0.709
1.907TrpAsn: 1.907 ± 0.783
0.953TrpPro: 0.953 ± 0.7
0.953TrpGln: 0.953 ± 0.709
0.0TrpArg: 0.0 ± 0.0
0.953TrpSer: 0.953 ± 0.909
0.953TrpThr: 0.953 ± 0.909
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.813TyrAla: 3.813 ± 1.928
0.953TyrCys: 0.953 ± 0.7
1.907TyrAsp: 1.907 ± 0.61
3.813TyrGlu: 3.813 ± 0.749
0.953TyrPhe: 0.953 ± 0.709
4.766TyrGly: 4.766 ± 1.246
0.0TyrHis: 0.0 ± 0.0
2.86TyrIle: 2.86 ± 1.186
1.907TyrLys: 1.907 ± 0.61
0.953TyrLeu: 0.953 ± 0.709
0.0TyrMet: 0.0 ± 0.0
4.766TyrAsn: 4.766 ± 0.966
0.0TyrPro: 0.0 ± 0.0
1.907TyrGln: 1.907 ± 1.817
1.907TyrArg: 1.907 ± 1.418
2.86TyrSer: 2.86 ± 1.541
0.0TyrThr: 0.0 ± 0.0
3.813TyrVal: 3.813 ± 1.22
0.953TyrTrp: 0.953 ± 0.709
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1050 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski