Amino acid dipepetide frequency for Ophiocordyceps camponoti-leonardi (nom. inval.)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.907AlaAla: 11.907 ± 0.094
1.215AlaCys: 1.215 ± 0.021
5.247AlaAsp: 5.247 ± 0.035
5.652AlaGlu: 5.652 ± 0.048
3.074AlaPhe: 3.074 ± 0.034
6.381AlaGly: 6.381 ± 0.049
1.841AlaHis: 1.841 ± 0.022
3.784AlaIle: 3.784 ± 0.034
4.102AlaLys: 4.102 ± 0.045
8.12AlaLeu: 8.12 ± 0.055
2.189AlaMet: 2.189 ± 0.024
2.756AlaAsn: 2.756 ± 0.033
4.955AlaPro: 4.955 ± 0.052
3.382AlaGln: 3.382 ± 0.034
6.025AlaArg: 6.025 ± 0.036
8.269AlaSer: 8.269 ± 0.062
5.364AlaThr: 5.364 ± 0.041
6.483AlaVal: 6.483 ± 0.055
1.186AlaTrp: 1.186 ± 0.02
2.061AlaTyr: 2.061 ± 0.033
0.0AlaXaa: 0.0 ± 0.0
Cys
1.019CysAla: 1.019 ± 0.018
0.265CysCys: 0.265 ± 0.01
0.729CysAsp: 0.729 ± 0.015
0.639CysGlu: 0.639 ± 0.014
0.559CysPhe: 0.559 ± 0.013
1.006CysGly: 1.006 ± 0.018
0.39CysHis: 0.39 ± 0.011
0.608CysIle: 0.608 ± 0.012
0.486CysLys: 0.486 ± 0.013
1.36CysLeu: 1.36 ± 0.02
0.252CysMet: 0.252 ± 0.007
0.404CysAsn: 0.404 ± 0.01
0.748CysPro: 0.748 ± 0.018
0.464CysGln: 0.464 ± 0.012
0.959CysArg: 0.959 ± 0.018
0.963CysSer: 0.963 ± 0.018
0.59CysThr: 0.59 ± 0.014
0.881CysVal: 0.881 ± 0.019
0.197CysTrp: 0.197 ± 0.008
0.338CysTyr: 0.338 ± 0.01
0.0CysXaa: 0.0 ± 0.0
Asp
5.768AspAla: 5.768 ± 0.047
0.714AspCys: 0.714 ± 0.016
6.545AspAsp: 6.545 ± 0.09
5.251AspGlu: 5.251 ± 0.045
2.239AspPhe: 2.239 ± 0.023
5.131AspGly: 5.131 ± 0.045
1.258AspHis: 1.258 ± 0.018
2.448AspIle: 2.448 ± 0.029
2.57AspLys: 2.57 ± 0.031
5.048AspLeu: 5.048 ± 0.041
1.438AspMet: 1.438 ± 0.02
1.762AspAsn: 1.762 ± 0.022
3.1AspPro: 3.1 ± 0.031
1.886AspGln: 1.886 ± 0.026
3.591AspArg: 3.591 ± 0.037
4.172AspSer: 4.172 ± 0.048
2.498AspThr: 2.498 ± 0.026
4.381AspVal: 4.381 ± 0.039
0.892AspTrp: 0.892 ± 0.016
1.503AspTyr: 1.503 ± 0.046
0.0AspXaa: 0.0 ± 0.0
Glu
6.488GluAla: 6.488 ± 0.053
0.617GluCys: 0.617 ± 0.015
4.141GluAsp: 4.141 ± 0.039
5.444GluGlu: 5.444 ± 0.057
1.705GluPhe: 1.705 ± 0.022
3.651GluGly: 3.651 ± 0.037
1.199GluHis: 1.199 ± 0.022
2.27GluIle: 2.27 ± 0.027
3.36GluLys: 3.36 ± 0.041
5.114GluLeu: 5.114 ± 0.044
1.542GluMet: 1.542 ± 0.019
1.799GluAsn: 1.799 ± 0.024
2.997GluPro: 2.997 ± 0.038
2.353GluGln: 2.353 ± 0.034
4.177GluArg: 4.177 ± 0.04
4.103GluSer: 4.103 ± 0.038
3.369GluThr: 3.369 ± 0.031
3.405GluVal: 3.405 ± 0.03
0.792GluTrp: 0.792 ± 0.014
1.373GluTyr: 1.373 ± 0.021
0.0GluXaa: 0.0 ± 0.0
Phe
3.018PheAla: 3.018 ± 0.03
0.567PheCys: 0.567 ± 0.012
2.26PheAsp: 2.26 ± 0.024
1.931PheGlu: 1.931 ± 0.025
1.527PhePhe: 1.527 ± 0.023
2.636PheGly: 2.636 ± 0.033
0.884PheHis: 0.884 ± 0.016
1.475PheIle: 1.475 ± 0.02
1.294PheLys: 1.294 ± 0.019
3.292PheLeu: 3.292 ± 0.037
0.701PheMet: 0.701 ± 0.013
1.222PheAsn: 1.222 ± 0.018
1.802PhePro: 1.802 ± 0.019
1.199PheGln: 1.199 ± 0.019
2.184PheArg: 2.184 ± 0.024
2.769PheSer: 2.769 ± 0.032
1.774PheThr: 1.774 ± 0.023
2.463PheVal: 2.463 ± 0.032
0.559PheTrp: 0.559 ± 0.014
0.968PheTyr: 0.968 ± 0.018
0.0PheXaa: 0.0 ± 0.0
Gly
5.465GlyAla: 5.465 ± 0.046
0.938GlyCys: 0.938 ± 0.019
4.103GlyAsp: 4.103 ± 0.039
3.796GlyGlu: 3.796 ± 0.033
2.689GlyPhe: 2.689 ± 0.033
7.459GlyGly: 7.459 ± 0.109
1.784GlyHis: 1.784 ± 0.023
3.035GlyIle: 3.035 ± 0.034
3.276GlyLys: 3.276 ± 0.037
6.18GlyLeu: 6.18 ± 0.051
1.499GlyMet: 1.499 ± 0.023
2.406GlyAsn: 2.406 ± 0.063
3.732GlyPro: 3.732 ± 0.124
2.64GlyGln: 2.64 ± 0.029
5.134GlyArg: 5.134 ± 0.048
6.15GlySer: 6.15 ± 0.085
3.54GlyThr: 3.54 ± 0.04
4.311GlyVal: 4.311 ± 0.041
1.13GlyTrp: 1.13 ± 0.019
1.913GlyTyr: 1.913 ± 0.036
0.0GlyXaa: 0.0 ± 0.0
His
1.898HisAla: 1.898 ± 0.021
0.347HisCys: 0.347 ± 0.01
1.501HisAsp: 1.501 ± 0.021
1.256HisGlu: 1.256 ± 0.023
0.835HisPhe: 0.835 ± 0.013
1.795HisGly: 1.795 ± 0.025
1.308HisHis: 1.308 ± 0.035
0.952HisIle: 0.952 ± 0.016
0.84HisLys: 0.84 ± 0.017
2.305HisLeu: 2.305 ± 0.026
0.498HisMet: 0.498 ± 0.012
0.722HisAsn: 0.722 ± 0.017
1.647HisPro: 1.647 ± 0.024
1.147HisGln: 1.147 ± 0.026
1.773HisArg: 1.773 ± 0.024
1.622HisSer: 1.622 ± 0.023
0.99HisThr: 0.99 ± 0.015
1.621HisVal: 1.621 ± 0.022
0.31HisTrp: 0.31 ± 0.009
0.637HisTyr: 0.637 ± 0.015
0.0HisXaa: 0.0 ± 0.0
Ile
3.392IleAla: 3.392 ± 0.037
0.659IleCys: 0.659 ± 0.013
2.567IleAsp: 2.567 ± 0.029
2.273IleGlu: 2.273 ± 0.028
1.658IlePhe: 1.658 ± 0.023
2.648IleGly: 2.648 ± 0.033
1.001IleHis: 1.001 ± 0.014
1.92IleIle: 1.92 ± 0.027
1.891IleLys: 1.891 ± 0.025
3.716IleLeu: 3.716 ± 0.037
0.901IleMet: 0.901 ± 0.015
1.476IleAsn: 1.476 ± 0.023
2.371IlePro: 2.371 ± 0.027
1.454IleGln: 1.454 ± 0.021
2.752IleArg: 2.752 ± 0.027
3.044IleSer: 3.044 ± 0.029
2.048IleThr: 2.048 ± 0.024
2.865IleVal: 2.865 ± 0.032
0.571IleTrp: 0.571 ± 0.014
1.071IleTyr: 1.071 ± 0.017
0.0IleXaa: 0.0 ± 0.0
Lys
4.408LysAla: 4.408 ± 0.045
0.48LysCys: 0.48 ± 0.014
2.57LysAsp: 2.57 ± 0.029
2.864LysGlu: 2.864 ± 0.03
1.222LysPhe: 1.222 ± 0.021
2.745LysGly: 2.745 ± 0.031
0.967LysHis: 0.967 ± 0.018
1.721LysIle: 1.721 ± 0.023
3.215LysLys: 3.215 ± 0.05
3.874LysLeu: 3.874 ± 0.038
1.072LysMet: 1.072 ± 0.017
1.405LysAsn: 1.405 ± 0.022
2.751LysPro: 2.751 ± 0.034
1.777LysGln: 1.777 ± 0.025
3.464LysArg: 3.464 ± 0.035
3.193LysSer: 3.193 ± 0.032
2.846LysThr: 2.846 ± 0.03
2.548LysVal: 2.548 ± 0.029
0.551LysTrp: 0.551 ± 0.012
1.061LysTyr: 1.061 ± 0.019
0.0LysXaa: 0.0 ± 0.0
Leu
8.639LeuAla: 8.639 ± 0.065
1.265LeuCys: 1.265 ± 0.019
5.527LeuAsp: 5.527 ± 0.04
5.176LeuGlu: 5.176 ± 0.05
3.188LeuPhe: 3.188 ± 0.036
5.977LeuGly: 5.977 ± 0.048
2.199LeuHis: 2.199 ± 0.026
3.407LeuIle: 3.407 ± 0.037
3.644LeuLys: 3.644 ± 0.037
8.856LeuLeu: 8.856 ± 0.078
1.844LeuMet: 1.844 ± 0.025
2.661LeuAsn: 2.661 ± 0.031
5.564LeuPro: 5.564 ± 0.048
3.59LeuGln: 3.59 ± 0.035
6.707LeuArg: 6.707 ± 0.049
7.448LeuSer: 7.448 ± 0.046
4.682LeuThr: 4.682 ± 0.032
6.025LeuVal: 6.025 ± 0.048
1.187LeuTrp: 1.187 ± 0.02
2.181LeuTyr: 2.181 ± 0.025
0.0LeuXaa: 0.0 ± 0.0
Met
2.562MetAla: 2.562 ± 0.026
0.232MetCys: 0.232 ± 0.007
1.287MetAsp: 1.287 ± 0.017
1.299MetGlu: 1.299 ± 0.019
0.655MetPhe: 0.655 ± 0.015
1.452MetGly: 1.452 ± 0.021
0.449MetHis: 0.449 ± 0.01
0.823MetIle: 0.823 ± 0.015
0.948MetLys: 0.948 ± 0.016
1.992MetLeu: 1.992 ± 0.025
0.667MetMet: 0.667 ± 0.014
0.688MetAsn: 0.688 ± 0.013
1.396MetPro: 1.396 ± 0.02
0.831MetGln: 0.831 ± 0.017
1.489MetArg: 1.489 ± 0.019
1.817MetSer: 1.817 ± 0.021
1.522MetThr: 1.522 ± 0.018
1.345MetVal: 1.345 ± 0.021
0.252MetTrp: 0.252 ± 0.008
0.459MetTyr: 0.459 ± 0.011
0.0MetXaa: 0.0 ± 0.0
Asn
2.712AsnAla: 2.712 ± 0.028
0.395AsnCys: 0.395 ± 0.009
1.829AsnAsp: 1.829 ± 0.024
1.668AsnGlu: 1.668 ± 0.024
1.156AsnPhe: 1.156 ± 0.021
2.653AsnGly: 2.653 ± 0.063
0.783AsnHis: 0.783 ± 0.015
1.454AsnIle: 1.454 ± 0.02
1.478AsnLys: 1.478 ± 0.021
2.803AsnLeu: 2.803 ± 0.029
0.769AsnMet: 0.769 ± 0.016
1.436AsnAsn: 1.436 ± 0.039
1.977AsnPro: 1.977 ± 0.025
1.132AsnGln: 1.132 ± 0.02
1.942AsnArg: 1.942 ± 0.025
2.297AsnSer: 2.297 ± 0.03
1.541AsnThr: 1.541 ± 0.021
2.099AsnVal: 2.099 ± 0.026
0.46AsnTrp: 0.46 ± 0.011
0.853AsnTyr: 0.853 ± 0.016
0.0AsnXaa: 0.0 ± 0.0
Pro
5.677ProAla: 5.677 ± 0.065
0.629ProCys: 0.629 ± 0.013
3.59ProAsp: 3.59 ± 0.067
3.447ProGlu: 3.447 ± 0.038
1.925ProPhe: 1.925 ± 0.024
4.073ProGly: 4.073 ± 0.075
1.35ProHis: 1.35 ± 0.02
2.064ProIle: 2.064 ± 0.024
2.33ProLys: 2.33 ± 0.032
4.998ProLeu: 4.998 ± 0.036
1.123ProMet: 1.123 ± 0.018
1.727ProAsn: 1.727 ± 0.024
6.526ProPro: 6.526 ± 0.097
2.459ProGln: 2.459 ± 0.038
4.023ProArg: 4.023 ± 0.04
6.386ProSer: 6.386 ± 0.06
3.712ProThr: 3.712 ± 0.045
3.791ProVal: 3.791 ± 0.035
0.751ProTrp: 0.751 ± 0.016
1.383ProTyr: 1.383 ± 0.022
0.0ProXaa: 0.0 ± 0.0
Gln
3.585GlnAla: 3.585 ± 0.037
0.403GlnCys: 0.403 ± 0.011
2.05GlnAsp: 2.05 ± 0.024
2.132GlnGlu: 2.132 ± 0.029
1.104GlnPhe: 1.104 ± 0.019
2.475GlnGly: 2.475 ± 0.03
1.181GlnHis: 1.181 ± 0.023
1.451GlnIle: 1.451 ± 0.021
1.706GlnLys: 1.706 ± 0.023
3.559GlnLeu: 3.559 ± 0.038
0.902GlnMet: 0.902 ± 0.018
1.174GlnAsn: 1.174 ± 0.022
2.761GlnPro: 2.761 ± 0.042
3.703GlnGln: 3.703 ± 0.107
2.961GlnArg: 2.961 ± 0.032
2.841GlnSer: 2.841 ± 0.037
2.129GlnThr: 2.129 ± 0.025
2.194GlnVal: 2.194 ± 0.026
0.494GlnTrp: 0.494 ± 0.013
0.938GlnTyr: 0.938 ± 0.016
0.0GlnXaa: 0.0 ± 0.0
Arg
5.636ArgAla: 5.636 ± 0.044
0.934ArgCys: 0.934 ± 0.018
4.138ArgAsp: 4.138 ± 0.04
4.162ArgGlu: 4.162 ± 0.039
2.396ArgPhe: 2.396 ± 0.027
4.481ArgGly: 4.481 ± 0.046
1.98ArgHis: 1.98 ± 0.025
2.86ArgIle: 2.86 ± 0.032
3.441ArgLys: 3.441 ± 0.038
6.823ArgLeu: 6.823 ± 0.046
1.432ArgMet: 1.432 ± 0.018
2.228ArgAsn: 2.228 ± 0.025
4.356ArgPro: 4.356 ± 0.044
3.124ArgGln: 3.124 ± 0.032
7.152ArgArg: 7.152 ± 0.063
5.389ArgSer: 5.389 ± 0.047
3.382ArgThr: 3.382 ± 0.034
3.831ArgVal: 3.831 ± 0.036
1.042ArgTrp: 1.042 ± 0.017
1.706ArgTyr: 1.706 ± 0.026
0.0ArgXaa: 0.0 ± 0.0
Ser
7.128SerAla: 7.128 ± 0.06
0.982SerCys: 0.982 ± 0.016
4.45SerAsp: 4.45 ± 0.041
3.873SerGlu: 3.873 ± 0.038
2.895SerPhe: 2.895 ± 0.027
5.658SerGly: 5.658 ± 0.065
1.931SerHis: 1.931 ± 0.024
3.275SerIle: 3.275 ± 0.035
3.351SerLys: 3.351 ± 0.031
7.508SerLeu: 7.508 ± 0.047
1.709SerMet: 1.709 ± 0.021
2.492SerAsn: 2.492 ± 0.031
5.861SerPro: 5.861 ± 0.07
3.11SerGln: 3.11 ± 0.037
5.903SerArg: 5.903 ± 0.046
10.578SerSer: 10.578 ± 0.141
4.998SerThr: 4.998 ± 0.051
4.771SerVal: 4.771 ± 0.036
1.106SerTrp: 1.106 ± 0.017
1.868SerTyr: 1.868 ± 0.028
0.0SerXaa: 0.0 ± 0.0
Thr
5.497ThrAla: 5.497 ± 0.042
0.711ThrCys: 0.711 ± 0.015
2.804ThrAsp: 2.804 ± 0.029
2.803ThrGlu: 2.803 ± 0.032
1.834ThrPhe: 1.834 ± 0.023
3.882ThrGly: 3.882 ± 0.041
1.08ThrHis: 1.08 ± 0.017
2.423ThrIle: 2.423 ± 0.026
2.305ThrLys: 2.305 ± 0.029
4.802ThrLeu: 4.802 ± 0.04
1.304ThrMet: 1.304 ± 0.018
1.613ThrAsn: 1.613 ± 0.019
3.858ThrPro: 3.858 ± 0.039
1.777ThrGln: 1.777 ± 0.023
3.282ThrArg: 3.282 ± 0.032
4.919ThrSer: 4.919 ± 0.05
4.635ThrThr: 4.635 ± 0.072
3.661ThrVal: 3.661 ± 0.034
0.746ThrTrp: 0.746 ± 0.014
1.292ThrTyr: 1.292 ± 0.022
0.0ThrXaa: 0.0 ± 0.0
Val
6.092ValAla: 6.092 ± 0.046
0.915ValCys: 0.915 ± 0.017
4.37ValAsp: 4.37 ± 0.036
4.104ValGlu: 4.104 ± 0.034
2.41ValPhe: 2.41 ± 0.029
4.232ValGly: 4.232 ± 0.042
1.343ValHis: 1.343 ± 0.02
2.67ValIle: 2.67 ± 0.027
2.894ValLys: 2.894 ± 0.029
5.687ValLeu: 5.687 ± 0.055
1.427ValMet: 1.427 ± 0.019
2.074ValAsn: 2.074 ± 0.026
3.635ValPro: 3.635 ± 0.029
2.264ValGln: 2.264 ± 0.022
4.165ValArg: 4.165 ± 0.035
4.775ValSer: 4.775 ± 0.043
3.534ValThr: 3.534 ± 0.035
5.048ValVal: 5.048 ± 0.052
0.85ValTrp: 0.85 ± 0.016
1.599ValTyr: 1.599 ± 0.022
0.0ValXaa: 0.0 ± 0.0
Trp
1.115TrpAla: 1.115 ± 0.019
0.197TrpCys: 0.197 ± 0.007
0.864TrpAsp: 0.864 ± 0.018
0.766TrpGlu: 0.766 ± 0.014
0.494TrpPhe: 0.494 ± 0.012
0.793TrpGly: 0.793 ± 0.015
0.379TrpHis: 0.379 ± 0.01
0.648TrpIle: 0.648 ± 0.014
0.667TrpLys: 0.667 ± 0.013
1.374TrpLeu: 1.374 ± 0.021
0.341TrpMet: 0.341 ± 0.009
0.553TrpAsn: 0.553 ± 0.013
0.631TrpPro: 0.631 ± 0.013
0.546TrpGln: 0.546 ± 0.012
1.097TrpArg: 1.097 ± 0.018
1.009TrpSer: 1.009 ± 0.017
0.891TrpThr: 0.891 ± 0.016
0.748TrpVal: 0.748 ± 0.015
0.27TrpTrp: 0.27 ± 0.008
0.35TrpTyr: 0.35 ± 0.01
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.985TyrAla: 1.985 ± 0.025
0.392TyrCys: 0.392 ± 0.011
1.621TyrAsp: 1.621 ± 0.02
1.363TyrGlu: 1.363 ± 0.025
0.961TyrPhe: 0.961 ± 0.016
2.05TyrGly: 2.05 ± 0.064
0.699TyrHis: 0.699 ± 0.014
0.989TyrIle: 0.989 ± 0.016
0.933TyrLys: 0.933 ± 0.017
2.355TyrLeu: 2.355 ± 0.026
0.555TyrMet: 0.555 ± 0.013
0.839TyrAsn: 0.839 ± 0.017
1.296TyrPro: 1.296 ± 0.021
0.907TyrGln: 0.907 ± 0.017
1.714TyrArg: 1.714 ± 0.024
1.704TyrSer: 1.704 ± 0.023
1.183TyrThr: 1.183 ± 0.021
1.621TyrVal: 1.621 ± 0.023
0.385TyrTrp: 0.385 ± 0.011
0.732TyrTyr: 0.732 ± 0.014
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7043 proteins (3884336 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski