Amino acid dipepetide frequency for Pantoea cypripedii (Pectobacterium cypripedii) (Erwinia cypripedii)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.508AlaAla: 11.508 ± 0.117	1.053AlaCys: 1.053 ± 0.025	5.275AlaAsp: 5.275 ± 0.051	6.004AlaGlu: 6.004 ± 0.064	3.643AlaPhe: 3.643 ± 0.05	8.161AlaGly: 8.161 ± 0.088	1.915AlaHis: 1.915 ± 0.035	5.918AlaIle: 5.918 ± 0.06	3.451AlaLys: 3.451 ± 0.051	12.767AlaLeu: 12.767 ± 0.112	3.025AlaMet: 3.025 ± 0.041	2.912AlaAsn: 2.912 ± 0.038	3.838AlaPro: 3.838 ± 0.053	5.118AlaGln: 5.118 ± 0.058	5.919AlaArg: 5.919 ± 0.067	6.089AlaSer: 6.089 ± 0.07	5.065AlaThr: 5.065 ± 0.066	7.007AlaVal: 7.007 ± 0.07	1.705AlaTrp: 1.705 ± 0.035	2.003AlaTyr: 2.003 ± 0.032	0.0AlaXaa: 0.0 ± 0.0
Cys	0.977CysAla: 0.977 ± 0.024	0.177CysCys: 0.177 ± 0.011	0.558CysAsp: 0.558 ± 0.017	0.5CysGlu: 0.5 ± 0.015	0.404CysPhe: 0.404 ± 0.014	0.995CysGly: 0.995 ± 0.023	0.309CysHis: 0.309 ± 0.015	0.522CysIle: 0.522 ± 0.018	0.264CysLys: 0.264 ± 0.01	1.014CysLeu: 1.014 ± 0.024	0.231CysMet: 0.231 ± 0.012	0.302CysAsn: 0.302 ± 0.013	0.449CysPro: 0.449 ± 0.015	0.493CysGln: 0.493 ± 0.016	0.598CysArg: 0.598 ± 0.017	0.616CysSer: 0.616 ± 0.017	0.443CysThr: 0.443 ± 0.016	0.689CysVal: 0.689 ± 0.019	0.166CysTrp: 0.166 ± 0.01	0.304CysTyr: 0.304 ± 0.013	0.0CysXaa: 0.0 ± 0.0
Asp	5.448AspAla: 5.448 ± 0.059	0.488AspCys: 0.488 ± 0.019	2.945AspAsp: 2.945 ± 0.045	3.35AspGlu: 3.35 ± 0.05	2.2AspPhe: 2.2 ± 0.037	3.758AspGly: 3.758 ± 0.064	1.101AspHis: 1.101 ± 0.028	3.251AspIle: 3.251 ± 0.042	2.239AspLys: 2.239 ± 0.043	4.849AspLeu: 4.849 ± 0.049	1.289AspMet: 1.289 ± 0.027	2.126AspAsn: 2.126 ± 0.038	2.296AspPro: 2.296 ± 0.033	1.924AspGln: 1.924 ± 0.037	2.906AspArg: 2.906 ± 0.044	2.895AspSer: 2.895 ± 0.041	2.473AspThr: 2.473 ± 0.049	3.791AspVal: 3.791 ± 0.044	0.858AspTrp: 0.858 ± 0.024	1.831AspTyr: 1.831 ± 0.029	0.001AspXaa: 0.001 ± 0.001
Glu	5.247GluAla: 5.247 ± 0.064	0.397GluCys: 0.397 ± 0.016	2.283GluAsp: 2.283 ± 0.04	3.049GluGlu: 3.049 ± 0.044	1.781GluPhe: 1.781 ± 0.031	3.355GluGly: 3.355 ± 0.049	1.282GluHis: 1.282 ± 0.029	3.129GluIle: 3.129 ± 0.052	2.865GluLys: 2.865 ± 0.051	5.71GluLeu: 5.71 ± 0.063	1.643GluMet: 1.643 ± 0.031	2.211GluAsn: 2.211 ± 0.041	2.039GluPro: 2.039 ± 0.035	3.379GluGln: 3.379 ± 0.046	3.364GluArg: 3.364 ± 0.048	2.829GluSer: 2.829 ± 0.043	2.731GluThr: 2.731 ± 0.042	3.644GluVal: 3.644 ± 0.047	0.757GluTrp: 0.757 ± 0.023	1.276GluTyr: 1.276 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	3.843PheAla: 3.843 ± 0.049	0.488PheCys: 0.488 ± 0.019	2.316PheAsp: 2.316 ± 0.04	1.571PheGlu: 1.571 ± 0.031	1.652PhePhe: 1.652 ± 0.036	3.101PheGly: 3.101 ± 0.046	0.836PheHis: 0.836 ± 0.024	2.438PheIle: 2.438 ± 0.037	1.124PheLys: 1.124 ± 0.03	3.395PheLeu: 3.395 ± 0.055	0.946PheMet: 0.946 ± 0.025	1.701PheAsn: 1.701 ± 0.029	1.655PhePro: 1.655 ± 0.03	1.271PheGln: 1.271 ± 0.024	1.985PheArg: 1.985 ± 0.034	3.215PheSer: 3.215 ± 0.037	2.348PheThr: 2.348 ± 0.043	2.465PheVal: 2.465 ± 0.04	0.644PheTrp: 0.644 ± 0.019	1.157PheTyr: 1.157 ± 0.026	0.0PheXaa: 0.0 ± 0.0
Gly	6.462GlyAla: 6.462 ± 0.075	0.951GlyCys: 0.951 ± 0.022	3.706GlyAsp: 3.706 ± 0.052	4.403GlyGlu: 4.403 ± 0.052	3.327GlyPhe: 3.327 ± 0.044	5.388GlyGly: 5.388 ± 0.074	1.704GlyHis: 1.704 ± 0.034	4.825GlyIle: 4.825 ± 0.06	3.65GlyLys: 3.65 ± 0.055	7.667GlyLeu: 7.667 ± 0.068	2.402GlyMet: 2.402 ± 0.041	2.747GlyAsn: 2.747 ± 0.055	2.132GlyPro: 2.132 ± 0.037	3.002GlyGln: 3.002 ± 0.047	3.892GlyArg: 3.892 ± 0.046	4.475GlySer: 4.475 ± 0.072	3.812GlyThr: 3.812 ± 0.079	5.714GlyVal: 5.714 ± 0.055	1.38GlyTrp: 1.38 ± 0.03	2.549GlyTyr: 2.549 ± 0.04	0.0GlyXaa: 0.0 ± 0.0
His	2.127HisAla: 2.127 ± 0.039	0.332HisCys: 0.332 ± 0.014	1.262HisAsp: 1.262 ± 0.029	1.087HisGlu: 1.087 ± 0.027	1.084HisPhe: 1.084 ± 0.028	1.759HisGly: 1.759 ± 0.031	0.799HisHis: 0.799 ± 0.02	1.288HisIle: 1.288 ± 0.027	0.72HisLys: 0.72 ± 0.02	2.418HisLeu: 2.418 ± 0.036	0.546HisMet: 0.546 ± 0.017	0.823HisAsn: 0.823 ± 0.021	1.415HisPro: 1.415 ± 0.027	1.365HisGln: 1.365 ± 0.028	1.291HisArg: 1.291 ± 0.027	1.389HisSer: 1.389 ± 0.028	1.073HisThr: 1.073 ± 0.022	1.155HisVal: 1.155 ± 0.023	0.467HisTrp: 0.467 ± 0.017	0.896HisTyr: 0.896 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	6.531IleAla: 6.531 ± 0.059	0.641IleCys: 0.641 ± 0.019	3.468IleAsp: 3.468 ± 0.046	3.114IleGlu: 3.114 ± 0.043	1.89IlePhe: 1.89 ± 0.032	4.481IleGly: 4.481 ± 0.053	1.157IleHis: 1.157 ± 0.028	3.163IleIle: 3.163 ± 0.044	2.12IleLys: 2.12 ± 0.035	4.713IleLeu: 4.713 ± 0.052	1.209IleMet: 1.209 ± 0.026	2.496IleAsn: 2.496 ± 0.038	2.627IlePro: 2.627 ± 0.035	1.873IleGln: 1.873 ± 0.031	3.02IleArg: 3.02 ± 0.047	3.94IleSer: 3.94 ± 0.055	3.506IleThr: 3.506 ± 0.049	3.631IleVal: 3.631 ± 0.045	0.7IleTrp: 0.7 ± 0.018	1.474IleTyr: 1.474 ± 0.024	0.0IleXaa: 0.0 ± 0.0
Lys	3.852LysAla: 3.852 ± 0.052	0.216LysCys: 0.216 ± 0.011	1.843LysAsp: 1.843 ± 0.038	2.0LysGlu: 2.0 ± 0.035	1.004LysPhe: 1.004 ± 0.028	2.663LysGly: 2.663 ± 0.043	0.78LysHis: 0.78 ± 0.021	2.175LysIle: 2.175 ± 0.038	1.983LysLys: 1.983 ± 0.039	3.821LysLeu: 3.821 ± 0.053	1.091LysMet: 1.091 ± 0.026	1.559LysAsn: 1.559 ± 0.031	1.943LysPro: 1.943 ± 0.036	1.865LysGln: 1.865 ± 0.037	2.296LysArg: 2.296 ± 0.031	2.217LysSer: 2.217 ± 0.037	2.332LysThr: 2.332 ± 0.04	2.713LysVal: 2.713 ± 0.049	0.442LysTrp: 0.442 ± 0.015	1.003LysTyr: 1.003 ± 0.03	0.0LysXaa: 0.0 ± 0.0
Leu	12.363LeuAla: 12.363 ± 0.106	1.21LeuCys: 1.21 ± 0.026	5.369LeuAsp: 5.369 ± 0.058	5.216LeuGlu: 5.216 ± 0.066	4.27LeuPhe: 4.27 ± 0.053	7.415LeuGly: 7.415 ± 0.074	2.452LeuHis: 2.452 ± 0.04	5.888LeuIle: 5.888 ± 0.061	4.225LeuLys: 4.225 ± 0.05	12.704LeuLeu: 12.704 ± 0.133	3.029LeuMet: 3.029 ± 0.038	4.247LeuAsn: 4.247 ± 0.055	6.014LeuPro: 6.014 ± 0.064	4.88LeuGln: 4.88 ± 0.061	6.478LeuArg: 6.478 ± 0.071	7.742LeuSer: 7.742 ± 0.073	6.567LeuThr: 6.567 ± 0.07	7.166LeuVal: 7.166 ± 0.076	1.432LeuTrp: 1.432 ± 0.036	2.517LeuTyr: 2.517 ± 0.043	0.0LeuXaa: 0.0 ± 0.0
Met	2.875MetAla: 2.875 ± 0.04	0.187MetCys: 0.187 ± 0.009	1.14MetAsp: 1.14 ± 0.024	1.116MetGlu: 1.116 ± 0.022	0.832MetPhe: 0.832 ± 0.024	1.792MetGly: 1.792 ± 0.033	0.516MetHis: 0.516 ± 0.016	1.436MetIle: 1.436 ± 0.03	1.392MetLys: 1.392 ± 0.03	3.177MetLeu: 3.177 ± 0.05	0.87MetMet: 0.87 ± 0.021	1.041MetAsn: 1.041 ± 0.022	1.343MetPro: 1.343 ± 0.026	1.331MetGln: 1.331 ± 0.027	1.544MetArg: 1.544 ± 0.028	1.909MetSer: 1.909 ± 0.034	1.765MetThr: 1.765 ± 0.03	1.891MetVal: 1.891 ± 0.031	0.273MetTrp: 0.273 ± 0.013	0.478MetTyr: 0.478 ± 0.018	0.001MetXaa: 0.001 ± 0.0
Asn	3.538AsnAla: 3.538 ± 0.041	0.346AsnCys: 0.346 ± 0.013	2.033AsnAsp: 2.033 ± 0.045	1.705AsnGlu: 1.705 ± 0.036	1.333AsnPhe: 1.333 ± 0.029	2.906AsnGly: 2.906 ± 0.047	0.842AsnHis: 0.842 ± 0.019	2.192AsnIle: 2.192 ± 0.034	1.348AsnLys: 1.348 ± 0.029	3.575AsnLeu: 3.575 ± 0.045	0.829AsnMet: 0.829 ± 0.022	1.555AsnAsn: 1.555 ± 0.036	2.094AsnPro: 2.094 ± 0.035	1.722AsnGln: 1.722 ± 0.04	1.983AsnArg: 1.983 ± 0.032	2.026AsnSer: 2.026 ± 0.043	1.897AsnThr: 1.897 ± 0.038	2.436AsnVal: 2.436 ± 0.038	0.588AsnTrp: 0.588 ± 0.019	1.089AsnTyr: 1.089 ± 0.028	0.0AsnXaa: 0.0 ± 0.0
Pro	5.15ProAla: 5.15 ± 0.058	0.357ProCys: 0.357 ± 0.014	2.946ProAsp: 2.946 ± 0.045	3.28ProGlu: 3.28 ± 0.047	1.821ProPhe: 1.821 ± 0.036	3.725ProGly: 3.725 ± 0.046	1.134ProHis: 1.134 ± 0.025	1.864ProIle: 1.864 ± 0.033	1.272ProLys: 1.272 ± 0.03	5.322ProLeu: 5.322 ± 0.06	1.112ProMet: 1.112 ± 0.021	1.263ProAsn: 1.263 ± 0.026	1.781ProPro: 1.781 ± 0.032	2.532ProGln: 2.532 ± 0.042	2.092ProArg: 2.092 ± 0.039	2.253ProSer: 2.253 ± 0.035	2.129ProThr: 2.129 ± 0.035	3.912ProVal: 3.912 ± 0.051	0.782ProTrp: 0.782 ± 0.021	1.184ProTyr: 1.184 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	5.136GlnAla: 5.136 ± 0.068	0.358GlnCys: 0.358 ± 0.014	2.016GlnAsp: 2.016 ± 0.033	2.063GlnGlu: 2.063 ± 0.038	1.545GlnPhe: 1.545 ± 0.029	3.442GlnGly: 3.442 ± 0.057	1.529GlnHis: 1.529 ± 0.03	2.316GlnIle: 2.316 ± 0.038	1.647GlnLys: 1.647 ± 0.034	5.815GlnLeu: 5.815 ± 0.068	1.275GlnMet: 1.275 ± 0.029	1.462GlnAsn: 1.462 ± 0.028	2.681GlnPro: 2.681 ± 0.042	4.414GlnGln: 4.414 ± 0.108	3.621GlnArg: 3.621 ± 0.056	2.507GlnSer: 2.507 ± 0.043	2.299GlnThr: 2.299 ± 0.036	3.199GlnVal: 3.199 ± 0.043	0.728GlnTrp: 0.728 ± 0.021	1.145GlnTyr: 1.145 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	4.967ArgAla: 4.967 ± 0.051	0.575ArgCys: 0.575 ± 0.019	3.14ArgAsp: 3.14 ± 0.046	3.649ArgGlu: 3.649 ± 0.053	2.592ArgPhe: 2.592 ± 0.035	3.459ArgGly: 3.459 ± 0.045	1.669ArgHis: 1.669 ± 0.03	3.326ArgIle: 3.326 ± 0.044	2.178ArgLys: 2.178 ± 0.041	6.767ArgLeu: 6.767 ± 0.073	1.57ArgMet: 1.57 ± 0.031	2.105ArgAsn: 2.105 ± 0.038	2.264ArgPro: 2.264 ± 0.036	3.371ArgGln: 3.371 ± 0.05	3.585ArgArg: 3.585 ± 0.053	2.967ArgSer: 2.967 ± 0.042	2.578ArgThr: 2.578 ± 0.039	3.954ArgVal: 3.954 ± 0.046	1.06ArgTrp: 1.06 ± 0.021	2.132ArgTyr: 2.132 ± 0.033	0.0ArgXaa: 0.0 ± 0.0
Ser	6.234SerAla: 6.234 ± 0.064	0.557SerCys: 0.557 ± 0.02	3.317SerAsp: 3.317 ± 0.045	3.149SerGlu: 3.149 ± 0.042	2.392SerPhe: 2.392 ± 0.04	5.634SerGly: 5.634 ± 0.066	1.499SerHis: 1.499 ± 0.029	2.906SerIle: 2.906 ± 0.046	1.893SerLys: 1.893 ± 0.036	7.1SerLeu: 7.1 ± 0.063	1.559SerMet: 1.559 ± 0.025	1.964SerAsn: 1.964 ± 0.041	2.742SerPro: 2.742 ± 0.042	2.764SerGln: 2.764 ± 0.044	3.494SerArg: 3.494 ± 0.038	3.768SerSer: 3.768 ± 0.057	3.091SerThr: 3.091 ± 0.052	4.342SerVal: 4.342 ± 0.058	1.124SerTrp: 1.124 ± 0.023	1.661SerTyr: 1.661 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	5.261ThrAla: 5.261 ± 0.073	0.443ThrCys: 0.443 ± 0.015	2.666ThrAsp: 2.666 ± 0.054	2.461ThrGlu: 2.461 ± 0.037	1.99ThrPhe: 1.99 ± 0.035	4.486ThrGly: 4.486 ± 0.065	1.274ThrHis: 1.274 ± 0.028	2.625ThrIle: 2.625 ± 0.043	1.379ThrLys: 1.379 ± 0.03	7.646ThrLeu: 7.646 ± 0.077	1.066ThrMet: 1.066 ± 0.026	1.465ThrAsn: 1.465 ± 0.037	3.392ThrPro: 3.392 ± 0.053	2.333ThrGln: 2.333 ± 0.042	3.126ThrArg: 3.126 ± 0.034	3.049ThrSer: 3.049 ± 0.054	2.905ThrThr: 2.905 ± 0.079	3.886ThrVal: 3.886 ± 0.077	0.77ThrTrp: 0.77 ± 0.021	1.133ThrTyr: 1.133 ± 0.025	0.0ThrXaa: 0.0 ± 0.0
Val	7.417ValAla: 7.417 ± 0.078	0.708ValCys: 0.708 ± 0.02	3.559ValAsp: 3.559 ± 0.045	3.535ValGlu: 3.535 ± 0.042	2.533ValPhe: 2.533 ± 0.044	4.602ValGly: 4.602 ± 0.058	1.264ValHis: 1.264 ± 0.027	4.527ValIle: 4.527 ± 0.051	2.746ValLys: 2.746 ± 0.041	7.35ValLeu: 7.35 ± 0.078	2.246ValMet: 2.246 ± 0.037	2.601ValAsn: 2.601 ± 0.04	3.109ValPro: 3.109 ± 0.039	2.536ValGln: 2.536 ± 0.037	3.773ValArg: 3.773 ± 0.046	4.736ValSer: 4.736 ± 0.059	4.384ValThr: 4.384 ± 0.069	5.355ValVal: 5.355 ± 0.06	0.94ValTrp: 0.94 ± 0.025	1.613ValTyr: 1.613 ± 0.03	0.0ValXaa: 0.0 ± 0.0
Trp	0.979TrpAla: 0.979 ± 0.023	0.183TrpCys: 0.183 ± 0.01	0.654TrpAsp: 0.654 ± 0.02	0.58TrpGlu: 0.58 ± 0.018	0.703TrpPhe: 0.703 ± 0.02	0.95TrpGly: 0.95 ± 0.024	0.505TrpHis: 0.505 ± 0.018	0.73TrpIle: 0.73 ± 0.024	0.473TrpLys: 0.473 ± 0.016	2.431TrpLeu: 2.431 ± 0.042	0.422TrpMet: 0.422 ± 0.017	0.498TrpAsn: 0.498 ± 0.019	0.748TrpPro: 0.748 ± 0.019	1.395TrpGln: 1.395 ± 0.033	1.125TrpArg: 1.125 ± 0.025	0.915TrpSer: 0.915 ± 0.028	0.608TrpThr: 0.608 ± 0.018	0.939TrpVal: 0.939 ± 0.022	0.24TrpTrp: 0.24 ± 0.013	0.422TrpTyr: 0.422 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.462TyrAla: 2.462 ± 0.035	0.346TyrCys: 0.346 ± 0.014	1.524TyrAsp: 1.524 ± 0.034	1.139TyrGlu: 1.139 ± 0.025	1.151TyrPhe: 1.151 ± 0.028	2.121TyrGly: 2.121 ± 0.037	0.726TyrHis: 0.726 ± 0.023	1.234TyrIle: 1.234 ± 0.028	0.826TyrLys: 0.826 ± 0.024	2.945TyrLeu: 2.945 ± 0.038	0.55TyrMet: 0.55 ± 0.017	0.956TyrAsn: 0.956 ± 0.024	1.346TyrPro: 1.346 ± 0.027	1.631TyrGln: 1.631 ± 0.032	1.818TyrArg: 1.818 ± 0.031	1.653TyrSer: 1.653 ± 0.032	1.35TyrThr: 1.35 ± 0.029	1.647TyrVal: 1.647 ± 0.027	0.443TyrTrp: 0.443 ± 0.017	0.835TyrTyr: 0.835 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.002XaaPhe: 0.002 ± 0.001	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5848 proteins (1873892 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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