Amino acid dipepetide frequency for Hubei permutotetra-like virus 10

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.58AlaAla: 4.58 ± 0.591
1.527AlaCys: 1.527 ± 0.79
0.0AlaAsp: 0.0 ± 0.0
3.053AlaGlu: 3.053 ± 0.099
3.053AlaPhe: 3.053 ± 0.099
9.16AlaGly: 9.16 ± 8.581
0.0AlaHis: 0.0 ± 0.0
2.29AlaIle: 2.29 ± 1.775
8.397AlaLys: 8.397 ± 1.576
4.58AlaLeu: 4.58 ± 3.551
0.0AlaMet: 0.0 ± 0.0
0.763AlaAsn: 0.763 ± 0.395
3.817AlaPro: 3.817 ± 0.494
3.817AlaGln: 3.817 ± 2.466
3.817AlaArg: 3.817 ± 0.494
3.817AlaSer: 3.817 ± 2.466
6.107AlaThr: 6.107 ± 2.761
6.107AlaVal: 6.107 ± 2.761
0.0AlaTrp: 0.0 ± 0.0
3.817AlaTyr: 3.817 ± 0.494
0.0AlaXaa: 0.0 ± 0.0
Cys
0.763CysAla: 0.763 ± 0.395
0.763CysCys: 0.763 ± 0.395
1.527CysAsp: 1.527 ± 0.69
2.29CysGlu: 2.29 ± 1.184
1.527CysPhe: 1.527 ± 0.79
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
1.527CysLys: 1.527 ± 0.69
2.29CysLeu: 2.29 ± 0.295
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.763CysGln: 0.763 ± 0.395
0.763CysArg: 0.763 ± 0.395
0.763CysSer: 0.763 ± 0.395
0.763CysThr: 0.763 ± 0.395
2.29CysVal: 2.29 ± 1.184
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.29AspAla: 2.29 ± 0.295
0.0AspCys: 0.0 ± 0.0
0.763AspAsp: 0.763 ± 0.395
2.29AspGlu: 2.29 ± 0.295
3.053AspPhe: 3.053 ± 1.579
6.87AspGly: 6.87 ± 0.886
0.763AspHis: 0.763 ± 0.395
6.87AspIle: 6.87 ± 0.886
3.053AspLys: 3.053 ± 0.099
7.634AspLeu: 7.634 ± 2.468
0.763AspMet: 0.763 ± 0.395
0.763AspAsn: 0.763 ± 0.395
0.763AspPro: 0.763 ± 0.395
2.29AspGln: 2.29 ± 0.295
4.58AspArg: 4.58 ± 0.889
5.344AspSer: 5.344 ± 1.676
1.527AspThr: 1.527 ± 0.79
2.29AspVal: 2.29 ± 1.184
2.29AspTrp: 2.29 ± 0.295
0.763AspTyr: 0.763 ± 0.395
0.0AspXaa: 0.0 ± 0.0
Glu
6.107GluAla: 6.107 ± 0.199
1.527GluCys: 1.527 ± 0.79
6.107GluAsp: 6.107 ± 1.679
12.214GluGlu: 12.214 ± 4.837
3.817GluPhe: 3.817 ± 0.494
6.107GluGly: 6.107 ± 1.679
1.527GluHis: 1.527 ± 0.79
3.053GluIle: 3.053 ± 1.579
9.16GluLys: 9.16 ± 1.182
5.344GluLeu: 5.344 ± 2.764
0.763GluMet: 0.763 ± 0.395
4.58GluAsn: 4.58 ± 0.889
0.763GluPro: 0.763 ± 0.395
3.053GluGln: 3.053 ± 1.579
7.634GluArg: 7.634 ± 2.468
4.58GluSer: 4.58 ± 0.591
2.29GluThr: 2.29 ± 1.184
8.397GluVal: 8.397 ± 0.097
2.29GluTrp: 2.29 ± 1.184
2.29GluTyr: 2.29 ± 1.184
0.0GluXaa: 0.0 ± 0.0
Phe
0.763PheAla: 0.763 ± 1.085
3.053PheCys: 3.053 ± 0.099
2.29PheAsp: 2.29 ± 0.295
3.053PheGlu: 3.053 ± 1.38
0.763PhePhe: 0.763 ± 0.395
1.527PheGly: 1.527 ± 0.79
0.763PheHis: 0.763 ± 0.395
0.763PheIle: 0.763 ± 0.395
5.344PheLys: 5.344 ± 0.196
4.58PheLeu: 4.58 ± 2.369
1.527PheMet: 1.527 ± 0.69
1.527PheAsn: 1.527 ± 0.69
0.763PhePro: 0.763 ± 0.395
0.763PheGln: 0.763 ± 0.395
1.527PheArg: 1.527 ± 0.79
4.58PheSer: 4.58 ± 0.889
2.29PheThr: 2.29 ± 0.295
1.527PheVal: 1.527 ± 0.79
0.763PheTrp: 0.763 ± 0.395
1.527PheTyr: 1.527 ± 0.69
0.0PheXaa: 0.0 ± 0.0
Gly
6.107GlyAla: 6.107 ± 2.761
0.763GlyCys: 0.763 ± 0.395
4.58GlyAsp: 4.58 ± 0.591
3.817GlyGlu: 3.817 ± 1.974
1.527GlyPhe: 1.527 ± 0.79
7.634GlyGly: 7.634 ± 0.988
0.0GlyHis: 0.0 ± 0.0
1.527GlyIle: 1.527 ± 0.69
5.344GlyLys: 5.344 ± 2.764
3.053GlyLeu: 3.053 ± 1.579
0.0GlyMet: 0.0 ± 0.0
2.29GlyAsn: 2.29 ± 0.295
3.053GlyPro: 3.053 ± 0.099
1.527GlyGln: 1.527 ± 0.79
3.053GlyArg: 3.053 ± 1.579
6.107GlySer: 6.107 ± 0.199
10.687GlyThr: 10.687 ± 7.792
3.817GlyVal: 3.817 ± 0.494
2.29GlyTrp: 2.29 ± 0.295
3.817GlyTyr: 3.817 ± 0.986
0.0GlyXaa: 0.0 ± 0.0
His
0.763HisAla: 0.763 ± 1.085
0.763HisCys: 0.763 ± 0.395
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
0.0HisIle: 0.0 ± 0.0
0.763HisLys: 0.763 ± 0.395
1.527HisLeu: 1.527 ± 0.79
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.763HisSer: 0.763 ± 0.395
1.527HisThr: 1.527 ± 0.79
0.763HisVal: 0.763 ± 0.395
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.29IleAla: 2.29 ± 0.295
0.763IleCys: 0.763 ± 0.395
1.527IleAsp: 1.527 ± 0.79
3.817IleGlu: 3.817 ± 0.494
2.29IlePhe: 2.29 ± 3.255
2.29IleGly: 2.29 ± 0.295
0.0IleHis: 0.0 ± 0.0
3.053IleIle: 3.053 ± 0.099
1.527IleLys: 1.527 ± 0.79
1.527IleLeu: 1.527 ± 0.79
1.527IleMet: 1.527 ± 0.79
0.763IleAsn: 0.763 ± 1.085
3.817IlePro: 3.817 ± 0.986
0.0IleGln: 0.0 ± 0.0
2.29IleArg: 2.29 ± 1.775
3.053IleSer: 3.053 ± 0.099
1.527IleThr: 1.527 ± 0.69
3.053IleVal: 3.053 ± 0.099
0.0IleTrp: 0.0 ± 0.0
2.29IleTyr: 2.29 ± 1.775
0.0IleXaa: 0.0 ± 0.0
Lys
6.107LysAla: 6.107 ± 1.281
0.0LysCys: 0.0 ± 0.0
3.053LysAsp: 3.053 ± 1.579
9.924LysGlu: 9.924 ± 3.653
4.58LysPhe: 4.58 ± 0.889
5.344LysGly: 5.344 ± 0.196
0.0LysHis: 0.0 ± 0.0
2.29LysIle: 2.29 ± 1.184
3.053LysLys: 3.053 ± 1.579
9.16LysLeu: 9.16 ± 1.778
3.817LysMet: 3.817 ± 2.466
3.817LysAsn: 3.817 ± 0.494
3.817LysPro: 3.817 ± 2.466
4.58LysGln: 4.58 ± 2.071
6.107LysArg: 6.107 ± 2.761
4.58LysSer: 4.58 ± 0.889
3.817LysThr: 3.817 ± 1.974
3.817LysVal: 3.817 ± 0.494
1.527LysTrp: 1.527 ± 0.79
1.527LysTyr: 1.527 ± 0.69
0.0LysXaa: 0.0 ± 0.0
Leu
3.817LeuAla: 3.817 ± 3.945
0.0LeuCys: 0.0 ± 0.0
6.107LeuAsp: 6.107 ± 1.281
10.687LeuGlu: 10.687 ± 5.528
2.29LeuPhe: 2.29 ± 0.295
1.527LeuGly: 1.527 ± 0.79
0.0LeuHis: 0.0 ± 0.0
4.58LeuIle: 4.58 ± 0.889
8.397LeuLys: 8.397 ± 1.383
4.58LeuLeu: 4.58 ± 2.369
3.053LeuMet: 3.053 ± 0.839
2.29LeuAsn: 2.29 ± 0.295
3.817LeuPro: 3.817 ± 1.974
3.817LeuGln: 3.817 ± 0.986
3.817LeuArg: 3.817 ± 1.974
6.107LeuSer: 6.107 ± 1.281
3.817LeuThr: 3.817 ± 0.986
12.977LeuVal: 12.977 ± 0.687
1.527LeuTrp: 1.527 ± 0.69
1.527LeuTyr: 1.527 ± 0.69
0.0LeuXaa: 0.0 ± 0.0
Met
1.527MetAla: 1.527 ± 0.69
0.763MetCys: 0.763 ± 0.395
2.29MetAsp: 2.29 ± 1.184
2.29MetGlu: 2.29 ± 0.295
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.527MetIle: 1.527 ± 0.79
2.29MetLys: 2.29 ± 0.295
3.817MetLeu: 3.817 ± 0.986
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
0.0MetPro: 0.0 ± 0.0
0.763MetGln: 0.763 ± 0.395
1.527MetArg: 1.527 ± 0.79
0.763MetSer: 0.763 ± 1.085
1.527MetThr: 1.527 ± 0.79
0.763MetVal: 0.763 ± 1.085
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.817AsnAla: 3.817 ± 0.494
0.763AsnCys: 0.763 ± 1.085
0.763AsnAsp: 0.763 ± 0.395
1.527AsnGlu: 1.527 ± 0.79
2.29AsnPhe: 2.29 ± 1.184
2.29AsnGly: 2.29 ± 1.184
0.0AsnHis: 0.0 ± 0.0
2.29AsnIle: 2.29 ± 0.295
2.29AsnLys: 2.29 ± 1.184
1.527AsnLeu: 1.527 ± 2.17
0.763AsnMet: 0.763 ± 0.395
0.763AsnAsn: 0.763 ± 0.395
5.344AsnPro: 5.344 ± 0.196
1.527AsnGln: 1.527 ± 0.79
2.29AsnArg: 2.29 ± 0.295
0.763AsnSer: 0.763 ± 1.085
0.763AsnThr: 0.763 ± 0.395
1.527AsnVal: 1.527 ± 0.69
0.763AsnTrp: 0.763 ± 1.085
1.527AsnTyr: 1.527 ± 2.17
0.0AsnXaa: 0.0 ± 0.0
Pro
4.58ProAla: 4.58 ± 2.071
0.0ProCys: 0.0 ± 0.0
6.107ProAsp: 6.107 ± 3.159
5.344ProGlu: 5.344 ± 0.196
3.053ProPhe: 3.053 ± 0.099
2.29ProGly: 2.29 ± 1.184
0.763ProHis: 0.763 ± 0.395
1.527ProIle: 1.527 ± 2.17
3.053ProLys: 3.053 ± 1.579
3.053ProLeu: 3.053 ± 1.579
0.0ProMet: 0.0 ± 0.0
1.527ProAsn: 1.527 ± 0.79
4.58ProPro: 4.58 ± 0.591
2.29ProGln: 2.29 ± 1.775
3.053ProArg: 3.053 ± 1.38
3.053ProSer: 3.053 ± 1.38
3.053ProThr: 3.053 ± 1.579
6.107ProVal: 6.107 ± 1.679
0.763ProTrp: 0.763 ± 1.085
0.763ProTyr: 0.763 ± 0.395
0.0ProXaa: 0.0 ± 0.0
Gln
4.58GlnAla: 4.58 ± 5.031
1.527GlnCys: 1.527 ± 0.79
3.053GlnAsp: 3.053 ± 1.579
1.527GlnGlu: 1.527 ± 0.79
1.527GlnPhe: 1.527 ± 0.69
3.053GlnGly: 3.053 ± 0.099
0.0GlnHis: 0.0 ± 0.0
0.763GlnIle: 0.763 ± 0.395
6.107GlnLys: 6.107 ± 1.281
2.29GlnLeu: 2.29 ± 1.184
0.763GlnMet: 0.763 ± 0.395
0.763GlnAsn: 0.763 ± 0.395
3.053GlnPro: 3.053 ± 0.099
1.527GlnGln: 1.527 ± 0.79
2.29GlnArg: 2.29 ± 0.295
1.527GlnSer: 1.527 ± 0.79
2.29GlnThr: 2.29 ± 0.295
0.763GlnVal: 0.763 ± 1.085
0.763GlnTrp: 0.763 ± 0.395
1.527GlnTyr: 1.527 ± 0.69
0.0GlnXaa: 0.0 ± 0.0
Arg
3.053ArgAla: 3.053 ± 0.099
0.0ArgCys: 0.0 ± 0.0
4.58ArgAsp: 4.58 ± 0.889
7.634ArgGlu: 7.634 ± 0.988
0.0ArgPhe: 0.0 ± 0.0
3.053ArgGly: 3.053 ± 0.099
0.0ArgHis: 0.0 ± 0.0
2.29ArgIle: 2.29 ± 1.775
5.344ArgLys: 5.344 ± 1.676
9.16ArgLeu: 9.16 ± 0.298
0.763ArgMet: 0.763 ± 1.085
0.763ArgAsn: 0.763 ± 0.395
3.817ArgPro: 3.817 ± 1.974
3.817ArgGln: 3.817 ± 0.494
1.527ArgArg: 1.527 ± 0.69
3.817ArgSer: 3.817 ± 1.974
0.763ArgThr: 0.763 ± 0.395
4.58ArgVal: 4.58 ± 2.369
0.0ArgTrp: 0.0 ± 0.0
1.527ArgTyr: 1.527 ± 0.79
0.0ArgXaa: 0.0 ± 0.0
Ser
4.58SerAla: 4.58 ± 3.551
2.29SerCys: 2.29 ± 0.295
3.053SerAsp: 3.053 ± 1.38
6.107SerGlu: 6.107 ± 0.199
2.29SerPhe: 2.29 ± 1.184
4.58SerGly: 4.58 ± 2.071
0.0SerHis: 0.0 ± 0.0
0.0SerIle: 0.0 ± 0.0
4.58SerLys: 4.58 ± 0.889
6.107SerLeu: 6.107 ± 2.761
1.527SerMet: 1.527 ± 0.69
3.053SerAsn: 3.053 ± 1.38
4.58SerPro: 4.58 ± 2.369
1.527SerGln: 1.527 ± 0.79
3.817SerArg: 3.817 ± 0.494
4.58SerSer: 4.58 ± 2.071
2.29SerThr: 2.29 ± 1.184
6.107SerVal: 6.107 ± 1.281
2.29SerTrp: 2.29 ± 1.184
0.763SerTyr: 0.763 ± 0.395
0.0SerXaa: 0.0 ± 0.0
Thr
3.053ThrAla: 3.053 ± 1.38
0.0ThrCys: 0.0 ± 0.0
3.053ThrAsp: 3.053 ± 1.38
8.397ThrGlu: 8.397 ± 2.863
0.763ThrPhe: 0.763 ± 1.085
8.397ThrGly: 8.397 ± 1.383
1.527ThrHis: 1.527 ± 0.69
1.527ThrIle: 1.527 ± 0.69
1.527ThrLys: 1.527 ± 0.69
5.344ThrLeu: 5.344 ± 1.676
0.763ThrMet: 0.763 ± 0.395
0.0ThrAsn: 0.0 ± 0.0
3.053ThrPro: 3.053 ± 1.38
1.527ThrGln: 1.527 ± 0.79
1.527ThrArg: 1.527 ± 0.79
3.817ThrSer: 3.817 ± 0.986
6.107ThrThr: 6.107 ± 2.761
3.053ThrVal: 3.053 ± 0.099
0.0ThrTrp: 0.0 ± 0.0
3.053ThrTyr: 3.053 ± 1.38
0.0ThrXaa: 0.0 ± 0.0
Val
4.58ValAla: 4.58 ± 0.591
1.527ValCys: 1.527 ± 0.79
3.817ValAsp: 3.817 ± 1.974
4.58ValGlu: 4.58 ± 0.889
2.29ValPhe: 2.29 ± 0.295
3.817ValGly: 3.817 ± 0.494
1.527ValHis: 1.527 ± 0.79
0.0ValIle: 0.0 ± 0.0
7.634ValLys: 7.634 ± 0.988
5.344ValLeu: 5.344 ± 1.676
0.763ValMet: 0.763 ± 0.395
5.344ValAsn: 5.344 ± 1.676
6.87ValPro: 6.87 ± 0.886
4.58ValGln: 4.58 ± 0.591
5.344ValArg: 5.344 ± 1.284
3.053ValSer: 3.053 ± 0.099
3.817ValThr: 3.817 ± 0.986
4.58ValVal: 4.58 ± 0.889
2.29ValTrp: 2.29 ± 1.184
2.29ValTyr: 2.29 ± 0.295
0.0ValXaa: 0.0 ± 0.0
Trp
3.053TrpAla: 3.053 ± 0.099
0.0TrpCys: 0.0 ± 0.0
0.763TrpAsp: 0.763 ± 1.085
1.527TrpGlu: 1.527 ± 0.79
0.763TrpPhe: 0.763 ± 0.395
0.763TrpGly: 0.763 ± 0.395
0.0TrpHis: 0.0 ± 0.0
1.527TrpIle: 1.527 ± 0.69
0.763TrpLys: 0.763 ± 0.395
0.0TrpLeu: 0.0 ± 0.0
0.763TrpMet: 0.763 ± 0.395
2.29TrpAsn: 2.29 ± 1.184
1.527TrpPro: 1.527 ± 0.79
0.0TrpGln: 0.0 ± 0.0
0.763TrpArg: 0.763 ± 0.395
1.527TrpSer: 1.527 ± 0.69
0.763TrpThr: 0.763 ± 1.085
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.763TrpTyr: 0.763 ± 0.395
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.29TyrAla: 2.29 ± 0.295
0.0TyrCys: 0.0 ± 0.0
1.527TyrAsp: 1.527 ± 2.17
1.527TyrGlu: 1.527 ± 0.69
3.817TyrPhe: 3.817 ± 0.494
2.29TyrGly: 2.29 ± 1.184
0.0TyrHis: 0.0 ± 0.0
1.527TyrIle: 1.527 ± 2.17
0.763TyrLys: 0.763 ± 1.085
4.58TyrLeu: 4.58 ± 0.591
1.527TyrMet: 1.527 ± 0.79
2.29TyrAsn: 2.29 ± 1.775
1.527TyrPro: 1.527 ± 0.69
1.527TyrGln: 1.527 ± 0.69
0.763TyrArg: 0.763 ± 0.395
1.527TyrSer: 1.527 ± 0.79
0.763TyrThr: 0.763 ± 0.395
1.527TyrVal: 1.527 ± 0.79
0.0TyrTrp: 0.0 ± 0.0
1.527TyrTyr: 1.527 ± 0.69
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1311 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski