Amino acid dipepetide frequency for Pepper golden mosaic virus-[CR]

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.814AlaAla: 5.814 ± 1.887
1.163AlaCys: 1.163 ± 1.002
0.0AlaAsp: 0.0 ± 0.0
2.326AlaGlu: 2.326 ± 1.178
1.163AlaPhe: 1.163 ± 0.71
4.651AlaGly: 4.651 ± 1.644
0.0AlaHis: 0.0 ± 0.0
1.163AlaIle: 1.163 ± 1.138
3.488AlaLys: 3.488 ± 1.103
8.14AlaLeu: 8.14 ± 2.106
0.0AlaMet: 0.0 ± 0.0
3.488AlaAsn: 3.488 ± 1.103
4.651AlaPro: 4.651 ± 1.17
5.814AlaGln: 5.814 ± 2.78
3.488AlaArg: 3.488 ± 2.13
5.814AlaSer: 5.814 ± 1.239
3.488AlaThr: 3.488 ± 2.096
3.488AlaVal: 3.488 ± 1.577
2.326AlaTrp: 2.326 ± 0.822
1.163AlaTyr: 1.163 ± 1.002
0.0AlaXaa: 0.0 ± 0.0
Cys
2.326CysAla: 2.326 ± 3.109
0.0CysCys: 0.0 ± 0.0
1.163CysAsp: 1.163 ± 0.71
2.326CysGlu: 2.326 ± 0.822
0.0CysPhe: 0.0 ± 0.0
1.163CysGly: 1.163 ± 1.555
0.0CysHis: 0.0 ± 0.0
1.163CysIle: 1.163 ± 1.002
3.488CysLys: 3.488 ± 1.165
1.163CysLeu: 1.163 ± 0.71
0.0CysMet: 0.0 ± 0.0
2.326CysAsn: 2.326 ± 1.42
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.163CysSer: 1.163 ± 1.555
1.163CysThr: 1.163 ± 1.002
2.326CysVal: 2.326 ± 0.822
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.326AspAla: 2.326 ± 0.822
0.0AspCys: 0.0 ± 0.0
5.814AspAsp: 5.814 ± 4.431
2.326AspGlu: 2.326 ± 0.822
3.488AspPhe: 3.488 ± 1.103
2.326AspGly: 2.326 ± 1.42
0.0AspHis: 0.0 ± 0.0
8.14AspIle: 8.14 ± 2.743
2.326AspLys: 2.326 ± 1.357
2.326AspLeu: 2.326 ± 1.495
1.163AspMet: 1.163 ± 0.71
1.163AspAsn: 1.163 ± 1.002
1.163AspPro: 1.163 ± 0.71
0.0AspGln: 0.0 ± 0.0
3.488AspArg: 3.488 ± 1.689
5.814AspSer: 5.814 ± 0.761
3.488AspThr: 3.488 ± 1.573
4.651AspVal: 4.651 ± 1.644
1.163AspTrp: 1.163 ± 0.71
1.163AspTyr: 1.163 ± 0.71
0.0AspXaa: 0.0 ± 0.0
Glu
4.651GluAla: 4.651 ± 1.17
0.0GluCys: 0.0 ± 0.0
1.163GluAsp: 1.163 ± 0.71
2.326GluGlu: 2.326 ± 1.42
1.163GluPhe: 1.163 ± 1.555
4.651GluGly: 4.651 ± 1.1
3.488GluHis: 3.488 ± 1.573
1.163GluIle: 1.163 ± 1.138
0.0GluLys: 0.0 ± 0.0
1.163GluLeu: 1.163 ± 0.71
1.163GluMet: 1.163 ± 0.71
5.814GluAsn: 5.814 ± 2.559
1.163GluPro: 1.163 ± 1.002
2.326GluGln: 2.326 ± 2.003
1.163GluArg: 1.163 ± 0.71
1.163GluSer: 1.163 ± 1.138
1.163GluThr: 1.163 ± 0.71
1.163GluVal: 1.163 ± 1.138
0.0GluTrp: 0.0 ± 0.0
2.326GluTyr: 2.326 ± 1.42
0.0GluXaa: 0.0 ± 0.0
Phe
1.163PheAla: 1.163 ± 1.138
1.163PheCys: 1.163 ± 1.002
3.488PheAsp: 3.488 ± 1.103
1.163PheGlu: 1.163 ± 1.002
3.488PhePhe: 3.488 ± 1.573
2.326PheGly: 2.326 ± 0.822
3.488PheHis: 3.488 ± 1.748
2.326PheIle: 2.326 ± 1.178
4.651PheLys: 4.651 ± 2.303
3.488PheLeu: 3.488 ± 1.577
0.0PheMet: 0.0 ± 0.0
4.651PheAsn: 4.651 ± 1.17
2.326PhePro: 2.326 ± 1.494
2.326PheGln: 2.326 ± 1.752
3.488PheArg: 3.488 ± 1.559
1.163PheSer: 1.163 ± 1.002
1.163PheThr: 1.163 ± 1.555
1.163PheVal: 1.163 ± 0.71
3.488PheTrp: 3.488 ± 2.014
2.326PheTyr: 2.326 ± 1.495
0.0PheXaa: 0.0 ± 0.0
Gly
2.326GlyAla: 2.326 ± 1.178
2.326GlyCys: 2.326 ± 1.495
3.488GlyAsp: 3.488 ± 2.13
4.651GlyGlu: 4.651 ± 1.698
2.326GlyPhe: 2.326 ± 1.494
3.488GlyGly: 3.488 ± 1.165
2.326GlyHis: 2.326 ± 1.494
3.488GlyIle: 3.488 ± 1.049
8.14GlyLys: 8.14 ± 3.257
0.0GlyLeu: 0.0 ± 0.0
1.163GlyMet: 1.163 ± 1.002
1.163GlyAsn: 1.163 ± 1.002
4.651GlyPro: 4.651 ± 1.486
3.488GlyGln: 3.488 ± 1.689
2.326GlyArg: 2.326 ± 1.494
4.651GlySer: 4.651 ± 2.988
4.651GlyThr: 4.651 ± 2.992
0.0GlyVal: 0.0 ± 0.0
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
2.326HisAla: 2.326 ± 0.822
2.326HisCys: 2.326 ± 1.494
1.163HisAsp: 1.163 ± 1.002
1.163HisGlu: 1.163 ± 1.138
1.163HisPhe: 1.163 ± 1.138
0.0HisGly: 0.0 ± 0.0
2.326HisHis: 2.326 ± 1.752
1.163HisIle: 1.163 ± 1.555
1.163HisLys: 1.163 ± 1.138
3.488HisLeu: 3.488 ± 2.13
0.0HisMet: 0.0 ± 0.0
4.651HisAsn: 4.651 ± 2.144
2.326HisPro: 2.326 ± 1.42
2.326HisGln: 2.326 ± 1.495
5.814HisArg: 5.814 ± 4.255
1.163HisSer: 1.163 ± 0.71
2.326HisThr: 2.326 ± 2.003
1.163HisVal: 1.163 ± 1.002
1.163HisTrp: 1.163 ± 0.71
1.163HisTyr: 1.163 ± 0.71
0.0HisXaa: 0.0 ± 0.0
Ile
2.326IleAla: 2.326 ± 1.494
0.0IleCys: 0.0 ± 0.0
2.326IleAsp: 2.326 ± 1.494
3.488IleGlu: 3.488 ± 1.577
4.651IlePhe: 4.651 ± 4.493
2.326IleGly: 2.326 ± 1.178
0.0IleHis: 0.0 ± 0.0
3.488IleIle: 3.488 ± 2.13
6.977IleLys: 6.977 ± 1.08
2.326IleLeu: 2.326 ± 1.494
1.163IleMet: 1.163 ± 1.138
2.326IleAsn: 2.326 ± 1.752
3.488IlePro: 3.488 ± 1.748
2.326IleGln: 2.326 ± 1.178
3.488IleArg: 3.488 ± 1.049
3.488IleSer: 3.488 ± 1.689
6.977IleThr: 6.977 ± 1.644
2.326IleVal: 2.326 ± 1.42
2.326IleTrp: 2.326 ± 1.357
4.651IleTyr: 4.651 ± 1.68
0.0IleXaa: 0.0 ± 0.0
Lys
4.651LysAla: 4.651 ± 1.1
1.163LysCys: 1.163 ± 0.71
5.814LysAsp: 5.814 ± 3.55
2.326LysGlu: 2.326 ± 1.42
2.326LysPhe: 2.326 ± 1.357
1.163LysGly: 1.163 ± 0.71
1.163LysHis: 1.163 ± 0.71
3.488LysIle: 3.488 ± 2.096
1.163LysLys: 1.163 ± 1.555
3.488LysLeu: 3.488 ± 1.049
1.163LysMet: 1.163 ± 1.166
5.814LysAsn: 5.814 ± 1.887
4.651LysPro: 4.651 ± 1.745
1.163LysGln: 1.163 ± 0.71
3.488LysArg: 3.488 ± 2.014
8.14LysSer: 8.14 ± 1.648
1.163LysThr: 1.163 ± 0.71
9.302LysVal: 9.302 ± 4.119
1.163LysTrp: 1.163 ± 0.71
3.488LysTyr: 3.488 ± 1.049
0.0LysXaa: 0.0 ± 0.0
Leu
1.163LeuAla: 1.163 ± 1.138
1.163LeuCys: 1.163 ± 0.71
4.651LeuAsp: 4.651 ± 1.698
3.488LeuGlu: 3.488 ± 1.573
2.326LeuPhe: 2.326 ± 1.178
4.651LeuGly: 4.651 ± 1.0
6.977LeuHis: 6.977 ± 3.211
2.326LeuIle: 2.326 ± 1.42
5.814LeuLys: 5.814 ± 1.887
2.326LeuLeu: 2.326 ± 2.003
1.163LeuMet: 1.163 ± 1.002
4.651LeuAsn: 4.651 ± 2.897
2.326LeuPro: 2.326 ± 1.494
2.326LeuGln: 2.326 ± 1.42
3.488LeuArg: 3.488 ± 1.049
2.326LeuSer: 2.326 ± 1.42
2.326LeuThr: 2.326 ± 1.42
2.326LeuVal: 2.326 ± 2.003
0.0LeuTrp: 0.0 ± 0.0
4.651LeuTyr: 4.651 ± 2.029
0.0LeuXaa: 0.0 ± 0.0
Met
2.326MetAla: 2.326 ± 2.003
1.163MetCys: 1.163 ± 1.002
3.488MetAsp: 3.488 ± 2.096
0.0MetGlu: 0.0 ± 0.0
1.163MetPhe: 1.163 ± 1.002
1.163MetGly: 1.163 ± 1.002
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
3.488MetLeu: 3.488 ± 1.573
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.163MetPro: 1.163 ± 0.71
1.163MetGln: 1.163 ± 0.71
0.0MetArg: 0.0 ± 0.0
0.0MetSer: 0.0 ± 0.0
1.163MetThr: 1.163 ± 1.138
1.163MetVal: 1.163 ± 1.002
1.163MetTrp: 1.163 ± 0.71
3.488MetTyr: 3.488 ± 3.005
0.0MetXaa: 0.0 ± 0.0
Asn
6.977AsnAla: 6.977 ± 3.074
3.488AsnCys: 3.488 ± 2.965
2.326AsnAsp: 2.326 ± 0.822
2.326AsnGlu: 2.326 ± 2.003
0.0AsnPhe: 0.0 ± 0.0
2.326AsnGly: 2.326 ± 1.495
4.651AsnHis: 4.651 ± 2.992
4.651AsnIle: 4.651 ± 1.745
2.326AsnLys: 2.326 ± 1.42
1.163AsnLeu: 1.163 ± 1.138
1.163AsnMet: 1.163 ± 1.84
4.651AsnAsn: 4.651 ± 1.0
3.488AsnPro: 3.488 ± 1.049
1.163AsnGln: 1.163 ± 1.555
2.326AsnArg: 2.326 ± 1.357
4.651AsnSer: 4.651 ± 1.0
0.0AsnThr: 0.0 ± 0.0
5.814AsnVal: 5.814 ± 2.777
0.0AsnTrp: 0.0 ± 0.0
5.814AsnTyr: 5.814 ± 1.502
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
1.163ProCys: 1.163 ± 1.002
1.163ProAsp: 1.163 ± 0.71
1.163ProGlu: 1.163 ± 0.71
0.0ProPhe: 0.0 ± 0.0
1.163ProGly: 1.163 ± 0.71
3.488ProHis: 3.488 ± 2.13
3.488ProIle: 3.488 ± 1.748
4.651ProLys: 4.651 ± 1.745
6.977ProLeu: 6.977 ± 3.154
2.326ProMet: 2.326 ± 2.003
2.326ProAsn: 2.326 ± 1.178
4.651ProPro: 4.651 ± 2.84
3.488ProGln: 3.488 ± 2.965
4.651ProArg: 4.651 ± 1.644
6.977ProSer: 6.977 ± 5.643
1.163ProThr: 1.163 ± 1.555
5.814ProVal: 5.814 ± 4.099
1.163ProTrp: 1.163 ± 1.002
2.326ProTyr: 2.326 ± 0.822
0.0ProXaa: 0.0 ± 0.0
Gln
3.488GlnAla: 3.488 ± 1.049
2.326GlnCys: 2.326 ± 1.42
3.488GlnAsp: 3.488 ± 2.965
1.163GlnGlu: 1.163 ± 1.002
2.326GlnPhe: 2.326 ± 1.42
0.0GlnGly: 0.0 ± 0.0
1.163GlnHis: 1.163 ± 1.555
1.163GlnIle: 1.163 ± 0.71
1.163GlnLys: 1.163 ± 0.71
1.163GlnLeu: 1.163 ± 0.71
0.0GlnMet: 0.0 ± 0.0
1.163GlnAsn: 1.163 ± 1.555
2.326GlnPro: 2.326 ± 3.109
0.0GlnGln: 0.0 ± 0.0
4.651GlnArg: 4.651 ± 1.17
3.488GlnSer: 3.488 ± 1.165
0.0GlnThr: 0.0 ± 0.0
4.651GlnVal: 4.651 ± 1.948
1.163GlnTrp: 1.163 ± 0.71
2.326GlnTyr: 2.326 ± 0.822
0.0GlnXaa: 0.0 ± 0.0
Arg
4.651ArgAla: 4.651 ± 2.355
1.163ArgCys: 1.163 ± 0.71
4.651ArgAsp: 4.651 ± 2.653
2.326ArgGlu: 2.326 ± 1.494
9.302ArgPhe: 9.302 ± 3.096
5.814ArgGly: 5.814 ± 3.403
1.163ArgHis: 1.163 ± 1.002
6.977ArgIle: 6.977 ± 3.117
1.163ArgLys: 1.163 ± 1.002
3.488ArgLeu: 3.488 ± 1.049
0.0ArgMet: 0.0 ± 0.0
0.0ArgAsn: 0.0 ± 0.0
5.814ArgPro: 5.814 ± 1.17
1.163ArgGln: 1.163 ± 1.138
8.14ArgArg: 8.14 ± 3.669
6.977ArgSer: 6.977 ± 1.24
4.651ArgThr: 4.651 ± 2.029
3.488ArgVal: 3.488 ± 1.049
0.0ArgTrp: 0.0 ± 0.0
1.163ArgTyr: 1.163 ± 1.002
0.0ArgXaa: 0.0 ± 0.0
Ser
6.977SerAla: 6.977 ± 2.466
0.0SerCys: 0.0 ± 0.0
3.488SerAsp: 3.488 ± 1.689
0.0SerGlu: 0.0 ± 0.0
6.977SerPhe: 6.977 ± 2.15
5.814SerGly: 5.814 ± 2.074
1.163SerHis: 1.163 ± 1.002
6.977SerIle: 6.977 ± 2.15
4.651SerLys: 4.651 ± 1.1
3.488SerLeu: 3.488 ± 2.965
2.326SerMet: 2.326 ± 1.117
5.814SerAsn: 5.814 ± 1.887
3.488SerPro: 3.488 ± 4.664
0.0SerGln: 0.0 ± 0.0
6.977SerArg: 6.977 ± 0.53
8.14SerSer: 8.14 ± 3.878
3.488SerThr: 3.488 ± 1.103
3.488SerVal: 3.488 ± 1.049
0.0SerTrp: 0.0 ± 0.0
3.488SerTyr: 3.488 ± 1.577
0.0SerXaa: 0.0 ± 0.0
Thr
3.488ThrAla: 3.488 ± 1.049
0.0ThrCys: 0.0 ± 0.0
1.163ThrAsp: 1.163 ± 1.138
1.163ThrGlu: 1.163 ± 1.002
2.326ThrPhe: 2.326 ± 0.822
5.814ThrGly: 5.814 ± 1.502
4.651ThrHis: 4.651 ± 1.486
0.0ThrIle: 0.0 ± 0.0
1.163ThrLys: 1.163 ± 0.71
2.326ThrLeu: 2.326 ± 1.495
1.163ThrMet: 1.163 ± 0.71
3.488ThrAsn: 3.488 ± 1.689
4.651ThrPro: 4.651 ± 1.1
1.163ThrGln: 1.163 ± 0.71
3.488ThrArg: 3.488 ± 2.296
3.488ThrSer: 3.488 ± 1.559
3.488ThrThr: 3.488 ± 2.513
2.326ThrVal: 2.326 ± 1.357
0.0ThrTrp: 0.0 ± 0.0
2.326ThrTyr: 2.326 ± 1.178
0.0ThrXaa: 0.0 ± 0.0
Val
1.163ValAla: 1.163 ± 0.71
0.0ValCys: 0.0 ± 0.0
0.0ValAsp: 0.0 ± 0.0
2.326ValGlu: 2.326 ± 1.178
2.326ValPhe: 2.326 ± 1.357
3.488ValGly: 3.488 ± 2.014
0.0ValHis: 0.0 ± 0.0
4.651ValIle: 4.651 ± 1.698
6.977ValLys: 6.977 ± 2.466
3.488ValLeu: 3.488 ± 1.049
3.488ValMet: 3.488 ± 3.005
4.651ValAsn: 4.651 ± 1.68
3.488ValPro: 3.488 ± 1.049
4.651ValGln: 4.651 ± 1.1
6.977ValArg: 6.977 ± 3.323
4.651ValSer: 4.651 ± 1.745
2.326ValThr: 2.326 ± 2.003
2.326ValVal: 2.326 ± 0.822
1.163ValTrp: 1.163 ± 1.138
4.651ValTyr: 4.651 ± 1.644
0.0ValXaa: 0.0 ± 0.0
Trp
1.163TrpAla: 1.163 ± 0.71
0.0TrpCys: 0.0 ± 0.0
1.163TrpAsp: 1.163 ± 1.555
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
3.488TrpLys: 3.488 ± 1.049
1.163TrpLeu: 1.163 ± 1.002
1.163TrpMet: 1.163 ± 1.002
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
1.163TrpGln: 1.163 ± 0.71
1.163TrpArg: 1.163 ± 1.002
1.163TrpSer: 1.163 ± 0.71
3.488TrpThr: 3.488 ± 1.577
1.163TrpVal: 1.163 ± 1.002
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.326TyrAla: 2.326 ± 2.003
1.163TyrCys: 1.163 ± 0.71
2.326TyrAsp: 2.326 ± 2.003
1.163TyrGlu: 1.163 ± 1.002
2.326TyrPhe: 2.326 ± 0.822
2.326TyrGly: 2.326 ± 0.822
2.326TyrHis: 2.326 ± 1.42
4.651TyrIle: 4.651 ± 2.144
3.488TyrLys: 3.488 ± 1.577
5.814TyrLeu: 5.814 ± 2.303
2.326TyrMet: 2.326 ± 1.224
2.326TyrAsn: 2.326 ± 0.822
2.326TyrPro: 2.326 ± 1.42
1.163TyrGln: 1.163 ± 1.002
3.488TyrArg: 3.488 ± 3.005
2.326TyrSer: 2.326 ± 0.822
0.0TyrThr: 0.0 ± 0.0
4.651TyrVal: 4.651 ± 2.714
0.0TyrTrp: 0.0 ± 0.0
1.163TyrTyr: 1.163 ± 1.138
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (861 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski