Amino acid dipepetide frequency for Neptunomonas concharum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.54AlaAla: 8.54 ± 0.104	1.06AlaCys: 1.06 ± 0.032	4.972AlaAsp: 4.972 ± 0.073	6.046AlaGlu: 6.046 ± 0.093	3.495AlaPhe: 3.495 ± 0.067	6.463AlaGly: 6.463 ± 0.097	1.821AlaHis: 1.821 ± 0.051	5.781AlaIle: 5.781 ± 0.079	4.166AlaLys: 4.166 ± 0.066	10.663AlaLeu: 10.663 ± 0.115	2.494AlaMet: 2.494 ± 0.059	3.024AlaAsn: 3.024 ± 0.061	3.178AlaPro: 3.178 ± 0.074	3.843AlaGln: 3.843 ± 0.075	4.183AlaArg: 4.183 ± 0.068	5.475AlaSer: 5.475 ± 0.079	4.5AlaThr: 4.5 ± 0.104	6.217AlaVal: 6.217 ± 0.091	0.978AlaTrp: 0.978 ± 0.032	2.448AlaTyr: 2.448 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.782CysAla: 0.782 ± 0.024	0.162CysCys: 0.162 ± 0.014	0.573CysAsp: 0.573 ± 0.025	0.66CysGlu: 0.66 ± 0.027	0.438CysPhe: 0.438 ± 0.017	0.923CysGly: 0.923 ± 0.029	0.362CysHis: 0.362 ± 0.021	0.602CysIle: 0.602 ± 0.021	0.412CysLys: 0.412 ± 0.02	1.054CysLeu: 1.054 ± 0.032	0.223CysMet: 0.223 ± 0.014	0.36CysAsn: 0.36 ± 0.014	0.477CysPro: 0.477 ± 0.023	0.44CysGln: 0.44 ± 0.02	0.534CysArg: 0.534 ± 0.025	0.733CysSer: 0.733 ± 0.028	0.515CysThr: 0.515 ± 0.023	0.637CysVal: 0.637 ± 0.023	0.152CysTrp: 0.152 ± 0.012	0.323CysTyr: 0.323 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	4.723AspAla: 4.723 ± 0.074	0.502AspCys: 0.502 ± 0.023	3.055AspAsp: 3.055 ± 0.085	3.967AspGlu: 3.967 ± 0.067	2.226AspPhe: 2.226 ± 0.052	3.561AspGly: 3.561 ± 0.072	1.302AspHis: 1.302 ± 0.037	3.853AspIle: 3.853 ± 0.064	2.776AspLys: 2.776 ± 0.061	5.834AspLeu: 5.834 ± 0.083	1.418AspMet: 1.418 ± 0.036	2.048AspAsn: 2.048 ± 0.063	2.381AspPro: 2.381 ± 0.042	2.563AspGln: 2.563 ± 0.052	2.67AspArg: 2.67 ± 0.052	2.956AspSer: 2.956 ± 0.056	2.821AspThr: 2.821 ± 0.084	3.794AspVal: 3.794 ± 0.087	0.805AspTrp: 0.805 ± 0.03	1.881AspTyr: 1.881 ± 0.075	0.0AspXaa: 0.0 ± 0.0
Glu	6.361GluAla: 6.361 ± 0.087	0.48GluCys: 0.48 ± 0.024	3.019GluAsp: 3.019 ± 0.085	4.113GluGlu: 4.113 ± 0.071	2.033GluPhe: 2.033 ± 0.048	4.343GluGly: 4.343 ± 0.082	1.64GluHis: 1.64 ± 0.046	3.845GluIle: 3.845 ± 0.072	3.592GluLys: 3.592 ± 0.078	6.861GluLeu: 6.861 ± 0.092	1.765GluMet: 1.765 ± 0.041	2.344GluAsn: 2.344 ± 0.05	2.387GluPro: 2.387 ± 0.11	3.768GluGln: 3.768 ± 0.072	3.841GluArg: 3.841 ± 0.072	3.843GluSer: 3.843 ± 0.057	3.411GluThr: 3.411 ± 0.067	4.574GluVal: 4.574 ± 0.066	0.805GluTrp: 0.805 ± 0.023	1.693GluTyr: 1.693 ± 0.039	0.0GluXaa: 0.0 ± 0.0
Phe	3.169PheAla: 3.169 ± 0.061	0.526PheCys: 0.526 ± 0.022	2.51PheAsp: 2.51 ± 0.047	2.499PheGlu: 2.499 ± 0.081	1.698PhePhe: 1.698 ± 0.043	2.942PheGly: 2.942 ± 0.057	0.777PheHis: 0.777 ± 0.029	2.534PheIle: 2.534 ± 0.048	1.71PheLys: 1.71 ± 0.042	3.649PheLeu: 3.649 ± 0.069	0.982PheMet: 0.982 ± 0.031	1.631PheAsn: 1.631 ± 0.043	1.52PhePro: 1.52 ± 0.035	1.299PheGln: 1.299 ± 0.04	1.739PheArg: 1.739 ± 0.047	3.178PheSer: 3.178 ± 0.062	2.206PheThr: 2.206 ± 0.069	2.524PheVal: 2.524 ± 0.056	0.526PheTrp: 0.526 ± 0.026	1.314PheTyr: 1.314 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	5.611GlyAla: 5.611 ± 0.08	0.974GlyCys: 0.974 ± 0.035	3.768GlyAsp: 3.768 ± 0.074	4.498GlyGlu: 4.498 ± 0.075	3.319GlyPhe: 3.319 ± 0.062	5.046GlyGly: 5.046 ± 0.093	1.685GlyHis: 1.685 ± 0.042	4.75GlyIle: 4.75 ± 0.073	3.654GlyLys: 3.654 ± 0.064	7.422GlyLeu: 7.422 ± 0.085	2.105GlyMet: 2.105 ± 0.047	2.384GlyAsn: 2.384 ± 0.053	1.828GlyPro: 1.828 ± 0.046	2.853GlyGln: 2.853 ± 0.062	3.56GlyArg: 3.56 ± 0.062	4.108GlySer: 4.108 ± 0.085	3.512GlyThr: 3.512 ± 0.071	5.567GlyVal: 5.567 ± 0.083	1.044GlyTrp: 1.044 ± 0.032	2.423GlyTyr: 2.423 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	1.784HisAla: 1.784 ± 0.047	0.339HisCys: 0.339 ± 0.017	1.145HisAsp: 1.145 ± 0.035	1.316HisGlu: 1.316 ± 0.032	1.104HisPhe: 1.104 ± 0.03	1.491HisGly: 1.491 ± 0.044	0.753HisHis: 0.753 ± 0.031	1.499HisIle: 1.499 ± 0.039	0.979HisLys: 0.979 ± 0.032	2.489HisLeu: 2.489 ± 0.057	0.542HisMet: 0.542 ± 0.021	0.852HisAsn: 0.852 ± 0.032	1.322HisPro: 1.322 ± 0.035	1.289HisGln: 1.289 ± 0.037	1.189HisArg: 1.189 ± 0.034	1.404HisSer: 1.404 ± 0.042	1.13HisThr: 1.13 ± 0.035	1.363HisVal: 1.363 ± 0.034	0.393HisTrp: 0.393 ± 0.018	0.857HisTyr: 0.857 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	6.023IleAla: 6.023 ± 0.081	0.688IleCys: 0.688 ± 0.027	4.023IleAsp: 4.023 ± 0.06	4.543IleGlu: 4.543 ± 0.077	2.09IlePhe: 2.09 ± 0.052	4.464IleGly: 4.464 ± 0.07	1.369IleHis: 1.369 ± 0.036	3.473IleIle: 3.473 ± 0.062	2.931IleLys: 2.931 ± 0.054	5.484IleLeu: 5.484 ± 0.082	1.246IleMet: 1.246 ± 0.037	2.737IleAsn: 2.737 ± 0.054	2.882IlePro: 2.882 ± 0.066	2.331IleGln: 2.331 ± 0.054	3.45IleArg: 3.45 ± 0.062	4.583IleSer: 4.583 ± 0.07	3.65IleThr: 3.65 ± 0.098	3.842IleVal: 3.842 ± 0.073	0.64IleTrp: 0.64 ± 0.027	1.698IleTyr: 1.698 ± 0.042	0.0IleXaa: 0.0 ± 0.0
Lys	4.722LysAla: 4.722 ± 0.086	0.258LysCys: 0.258 ± 0.017	2.406LysAsp: 2.406 ± 0.053	3.236LysGlu: 3.236 ± 0.068	1.173LysPhe: 1.173 ± 0.04	3.37LysGly: 3.37 ± 0.062	1.141LysHis: 1.141 ± 0.033	2.568LysIle: 2.568 ± 0.053	2.557LysLys: 2.557 ± 0.062	4.561LysLeu: 4.561 ± 0.073	1.279LysMet: 1.279 ± 0.039	1.759LysAsn: 1.759 ± 0.047	2.241LysPro: 2.241 ± 0.058	2.525LysGln: 2.525 ± 0.05	2.914LysArg: 2.914 ± 0.057	2.804LysSer: 2.804 ± 0.054	2.72LysThr: 2.72 ± 0.052	3.436LysVal: 3.436 ± 0.059	0.441LysTrp: 0.441 ± 0.022	1.081LysTyr: 1.081 ± 0.036	0.0LysXaa: 0.0 ± 0.0
Leu	9.964LeuAla: 9.964 ± 0.116	1.133LeuCys: 1.133 ± 0.033	5.934LeuAsp: 5.934 ± 0.086	6.545LeuGlu: 6.545 ± 0.097	4.286LeuPhe: 4.286 ± 0.08	7.278LeuGly: 7.278 ± 0.091	2.269LeuHis: 2.269 ± 0.057	6.556LeuIle: 6.556 ± 0.092	5.533LeuLys: 5.533 ± 0.084	11.898LeuLeu: 11.898 ± 0.176	2.867LeuMet: 2.867 ± 0.05	4.45LeuAsn: 4.45 ± 0.072	5.09LeuPro: 5.09 ± 0.077	4.199LeuGln: 4.199 ± 0.076	5.11LeuArg: 5.11 ± 0.08	8.46LeuSer: 8.46 ± 0.103	5.878LeuThr: 5.878 ± 0.074	6.991LeuVal: 6.991 ± 0.088	1.195LeuTrp: 1.195 ± 0.037	2.715LeuTyr: 2.715 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	2.574MetAla: 2.574 ± 0.054	0.203MetCys: 0.203 ± 0.013	1.397MetAsp: 1.397 ± 0.037	1.376MetGlu: 1.376 ± 0.039	0.808MetPhe: 0.808 ± 0.032	1.862MetGly: 1.862 ± 0.049	0.523MetHis: 0.523 ± 0.026	1.587MetIle: 1.587 ± 0.04	1.383MetLys: 1.383 ± 0.038	2.763MetLeu: 2.763 ± 0.054	0.801MetMet: 0.801 ± 0.026	0.987MetAsn: 0.987 ± 0.028	1.257MetPro: 1.257 ± 0.036	1.154MetGln: 1.154 ± 0.035	1.277MetArg: 1.277 ± 0.038	1.978MetSer: 1.978 ± 0.041	1.513MetThr: 1.513 ± 0.043	1.749MetVal: 1.749 ± 0.045	0.196MetTrp: 0.196 ± 0.012	0.448MetTyr: 0.448 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.039AsnAla: 3.039 ± 0.056	0.367AsnCys: 0.367 ± 0.021	2.038AsnAsp: 2.038 ± 0.05	2.238AsnGlu: 2.238 ± 0.048	1.243AsnPhe: 1.243 ± 0.03	2.552AsnGly: 2.552 ± 0.059	0.882AsnHis: 0.882 ± 0.034	2.395AsnIle: 2.395 ± 0.043	1.72AsnLys: 1.72 ± 0.047	3.769AsnLeu: 3.769 ± 0.059	0.839AsnMet: 0.839 ± 0.027	1.527AsnAsn: 1.527 ± 0.042	2.099AsnPro: 2.099 ± 0.041	1.788AsnGln: 1.788 ± 0.044	2.011AsnArg: 2.011 ± 0.047	2.139AsnSer: 2.139 ± 0.048	2.139AsnThr: 2.139 ± 0.048	2.224AsnVal: 2.224 ± 0.047	0.485AsnTrp: 0.485 ± 0.021	1.108AsnTyr: 1.108 ± 0.038	0.0AsnXaa: 0.0 ± 0.0
Pro	3.676ProAla: 3.676 ± 0.08	0.347ProCys: 0.347 ± 0.018	2.939ProAsp: 2.939 ± 0.054	3.633ProGlu: 3.633 ± 0.059	1.857ProPhe: 1.857 ± 0.079	2.691ProGly: 2.691 ± 0.052	0.887ProHis: 0.887 ± 0.03	2.476ProIle: 2.476 ± 0.051	1.852ProLys: 1.852 ± 0.047	4.544ProLeu: 4.544 ± 0.064	1.042ProMet: 1.042 ± 0.032	1.52ProAsn: 1.52 ± 0.039	1.42ProPro: 1.42 ± 0.048	1.641ProGln: 1.641 ± 0.037	1.572ProArg: 1.572 ± 0.04	2.717ProSer: 2.717 ± 0.058	2.203ProThr: 2.203 ± 0.071	3.535ProVal: 3.535 ± 0.073	0.524ProTrp: 0.524 ± 0.022	1.228ProTyr: 1.228 ± 0.034	0.0ProXaa: 0.0 ± 0.0
Gln	4.481GlnAla: 4.481 ± 0.077	0.358GlnCys: 0.358 ± 0.02	1.916GlnAsp: 1.916 ± 0.045	2.491GlnGlu: 2.491 ± 0.048	1.554GlnPhe: 1.554 ± 0.038	3.158GlnGly: 3.158 ± 0.06	1.212GlnHis: 1.212 ± 0.035	2.59GlnIle: 2.59 ± 0.039	2.0GlnLys: 2.0 ± 0.047	5.281GlnLeu: 5.281 ± 0.091	1.115GlnMet: 1.115 ± 0.031	1.408GlnAsn: 1.408 ± 0.036	1.985GlnPro: 1.985 ± 0.042	2.948GlnGln: 2.948 ± 0.059	2.713GlnArg: 2.713 ± 0.057	2.719GlnSer: 2.719 ± 0.058	2.272GlnThr: 2.272 ± 0.051	3.133GlnVal: 3.133 ± 0.049	0.649GlnTrp: 0.649 ± 0.029	1.125GlnTyr: 1.125 ± 0.035	0.0GlnXaa: 0.0 ± 0.0
Arg	3.963ArgAla: 3.963 ± 0.068	0.569ArgCys: 0.569 ± 0.026	2.56ArgAsp: 2.56 ± 0.051	3.364ArgGlu: 3.364 ± 0.065	2.534ArgPhe: 2.534 ± 0.055	2.907ArgGly: 2.907 ± 0.058	1.327ArgHis: 1.327 ± 0.034	3.515ArgIle: 3.515 ± 0.051	2.464ArgLys: 2.464 ± 0.053	6.03ArgLeu: 6.03 ± 0.088	1.421ArgMet: 1.421 ± 0.04	1.79ArgAsn: 1.79 ± 0.039	1.886ArgPro: 1.886 ± 0.041	2.524ArgGln: 2.524 ± 0.054	2.81ArgArg: 2.81 ± 0.065	3.147ArgSer: 3.147 ± 0.064	2.383ArgThr: 2.383 ± 0.043	3.516ArgVal: 3.516 ± 0.056	0.804ArgTrp: 0.804 ± 0.029	1.899ArgTyr: 1.899 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	5.7SerAla: 5.7 ± 0.086	0.642SerCys: 0.642 ± 0.025	3.677SerAsp: 3.677 ± 0.056	4.065SerGlu: 4.065 ± 0.061	2.731SerPhe: 2.731 ± 0.053	5.264SerGly: 5.264 ± 0.084	1.601SerHis: 1.601 ± 0.037	4.016SerIle: 4.016 ± 0.057	2.731SerLys: 2.731 ± 0.062	7.221SerLeu: 7.221 ± 0.087	1.632SerMet: 1.632 ± 0.039	2.192SerAsn: 2.192 ± 0.05	2.779SerPro: 2.779 ± 0.05	2.779SerGln: 2.779 ± 0.053	3.342SerArg: 3.342 ± 0.064	4.241SerSer: 4.241 ± 0.08	3.266SerThr: 3.266 ± 0.069	4.748SerVal: 4.748 ± 0.102	0.801SerTrp: 0.801 ± 0.031	1.914SerTyr: 1.914 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	4.581ThrAla: 4.581 ± 0.089	0.509ThrCys: 0.509 ± 0.022	2.995ThrAsp: 2.995 ± 0.109	3.247ThrGlu: 3.247 ± 0.061	1.988ThrPhe: 1.988 ± 0.068	4.207ThrGly: 4.207 ± 0.082	1.299ThrHis: 1.299 ± 0.037	3.018ThrIle: 3.018 ± 0.15	1.758ThrLys: 1.758 ± 0.042	6.823ThrLeu: 6.823 ± 0.098	1.079ThrMet: 1.079 ± 0.034	1.636ThrAsn: 1.636 ± 0.045	2.992ThrPro: 2.992 ± 0.068	2.476ThrGln: 2.476 ± 0.056	2.542ThrArg: 2.542 ± 0.048	3.282ThrSer: 3.282 ± 0.074	3.031ThrThr: 3.031 ± 0.213	3.727ThrVal: 3.727 ± 0.182	0.562ThrTrp: 0.562 ± 0.025	1.519ThrTyr: 1.519 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	6.522ValAla: 6.522 ± 0.086	0.746ValCys: 0.746 ± 0.028	4.043ValAsp: 4.043 ± 0.083	4.583ValGlu: 4.583 ± 0.079	2.635ValPhe: 2.635 ± 0.058	4.701ValGly: 4.701 ± 0.076	1.321ValHis: 1.321 ± 0.039	4.759ValIle: 4.759 ± 0.066	3.251ValLys: 3.251 ± 0.067	6.999ValLeu: 6.999 ± 0.097	2.044ValMet: 2.044 ± 0.046	2.571ValAsn: 2.571 ± 0.051	2.672ValPro: 2.672 ± 0.058	2.305ValGln: 2.305 ± 0.053	3.376ValArg: 3.376 ± 0.056	5.017ValSer: 5.017 ± 0.109	4.152ValThr: 4.152 ± 0.213	5.322ValVal: 5.322 ± 0.099	0.744ValTrp: 0.744 ± 0.028	1.774ValTyr: 1.774 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	0.853TrpAla: 0.853 ± 0.028	0.156TrpCys: 0.156 ± 0.012	0.604TrpAsp: 0.604 ± 0.031	0.61TrpGlu: 0.61 ± 0.023	0.558TrpPhe: 0.558 ± 0.021	0.798TrpGly: 0.798 ± 0.031	0.34TrpHis: 0.34 ± 0.02	0.716TrpIle: 0.716 ± 0.03	0.575TrpLys: 0.575 ± 0.021	1.736TrpLeu: 1.736 ± 0.049	0.337TrpMet: 0.337 ± 0.017	0.447TrpAsn: 0.447 ± 0.019	0.488TrpPro: 0.488 ± 0.023	0.742TrpGln: 0.742 ± 0.03	0.688TrpArg: 0.688 ± 0.024	0.793TrpSer: 0.793 ± 0.032	0.489TrpThr: 0.489 ± 0.023	0.944TrpVal: 0.944 ± 0.033	0.182TrpTrp: 0.182 ± 0.014	0.328TrpTyr: 0.328 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.282TyrAla: 2.282 ± 0.05	0.342TyrCys: 0.342 ± 0.016	1.56TyrAsp: 1.56 ± 0.042	1.687TyrGlu: 1.687 ± 0.038	1.164TyrPhe: 1.164 ± 0.031	2.087TyrGly: 2.087 ± 0.052	0.731TyrHis: 0.731 ± 0.026	1.615TyrIle: 1.615 ± 0.037	1.148TyrLys: 1.148 ± 0.037	3.27TyrLeu: 3.27 ± 0.066	0.602TyrMet: 0.602 ± 0.025	0.935TyrAsn: 0.935 ± 0.029	1.422TyrPro: 1.422 ± 0.043	1.641TyrGln: 1.641 ± 0.041	1.889TyrArg: 1.889 ± 0.049	1.766TyrSer: 1.766 ± 0.038	1.481TyrThr: 1.481 ± 0.067	1.697TyrVal: 1.697 ± 0.044	0.458TyrTrp: 0.458 ± 0.019	0.897TyrTyr: 0.897 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3270 proteins (1078637 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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