Amino acid dipepetide frequency for Fenneropenaeus chinensis hepatopancreatic densovirus (isolate Shrimp/China/HB/2008)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.559AlaAla: 5.559 ± 2.387
0.695AlaCys: 0.695 ± 0.533
2.78AlaAsp: 2.78 ± 1.126
2.085AlaGlu: 2.085 ± 1.951
1.39AlaPhe: 1.39 ± 1.301
2.78AlaGly: 2.78 ± 1.832
1.39AlaHis: 1.39 ± 0.563
6.254AlaIle: 6.254 ± 1.184
4.17AlaLys: 4.17 ± 0.363
5.559AlaLeu: 5.559 ± 3.333
0.695AlaMet: 0.695 ± 0.597
2.78AlaAsn: 2.78 ± 0.713
2.78AlaPro: 2.78 ± 2.602
1.39AlaGln: 1.39 ± 0.519
2.085AlaArg: 2.085 ± 0.181
5.559AlaSer: 5.559 ± 2.387
1.39AlaThr: 1.39 ± 1.301
2.085AlaVal: 2.085 ± 1.049
0.695AlaTrp: 0.695 ± 0.65
1.39AlaTyr: 1.39 ± 1.067
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.695CysCys: 0.695 ± 0.533
0.695CysAsp: 0.695 ± 0.597
0.0CysGlu: 0.0 ± 0.0
1.39CysPhe: 1.39 ± 1.194
1.39CysGly: 1.39 ± 0.563
0.0CysHis: 0.0 ± 0.0
1.39CysIle: 1.39 ± 0.563
4.17CysLys: 4.17 ± 0.783
0.0CysLeu: 0.0 ± 0.0
0.695CysMet: 0.695 ± 0.533
0.0CysAsn: 0.0 ± 0.0
0.695CysPro: 0.695 ± 0.597
0.695CysGln: 0.695 ± 0.533
0.0CysArg: 0.0 ± 0.0
1.39CysSer: 1.39 ± 1.301
0.695CysThr: 0.695 ± 0.533
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.39CysTyr: 1.39 ± 0.563
0.0CysXaa: 0.0 ± 0.0
Asp
1.39AspAla: 1.39 ± 0.519
0.695AspCys: 0.695 ± 0.533
3.475AspAsp: 3.475 ± 1.429
4.864AspGlu: 4.864 ± 2.493
2.78AspPhe: 2.78 ± 1.126
4.864AspGly: 4.864 ± 1.967
0.695AspHis: 0.695 ± 0.533
2.78AspIle: 2.78 ± 1.292
3.475AspLys: 3.475 ± 0.526
4.864AspLeu: 4.864 ± 0.172
1.39AspMet: 1.39 ± 1.194
4.864AspAsn: 4.864 ± 0.853
0.695AspPro: 0.695 ± 0.65
2.085AspGln: 2.085 ± 1.951
4.864AspArg: 4.864 ± 1.123
3.475AspSer: 3.475 ± 1.522
2.085AspThr: 2.085 ± 1.049
1.39AspVal: 1.39 ± 1.194
0.0AspTrp: 0.0 ± 0.0
0.695AspTyr: 0.695 ± 0.533
0.0AspXaa: 0.0 ± 0.0
Glu
3.475GluAla: 3.475 ± 1.415
2.085GluCys: 2.085 ± 0.181
5.559GluAsp: 5.559 ± 1.543
9.729GluGlu: 9.729 ± 4.188
1.39GluPhe: 1.39 ± 0.715
3.475GluGly: 3.475 ± 0.498
3.475GluHis: 3.475 ± 1.549
2.085GluIle: 2.085 ± 1.049
9.034GluLys: 9.034 ± 2.075
5.559GluLeu: 5.559 ± 0.541
2.085GluMet: 2.085 ± 0.828
6.949GluAsn: 6.949 ± 2.766
3.475GluPro: 3.475 ± 0.896
3.475GluGln: 3.475 ± 0.896
2.78GluArg: 2.78 ± 1.667
1.39GluSer: 1.39 ± 1.067
4.17GluThr: 4.17 ± 2.064
3.475GluVal: 3.475 ± 1.813
0.695GluTrp: 0.695 ± 0.597
4.864GluTyr: 4.864 ± 2.493
0.0GluXaa: 0.0 ± 0.0
Phe
4.17PheAla: 4.17 ± 1.312
0.695PheCys: 0.695 ± 0.597
0.695PheAsp: 0.695 ± 0.65
2.78PheGlu: 2.78 ± 1.038
2.085PhePhe: 2.085 ± 1.03
0.695PheGly: 0.695 ± 0.597
0.695PheHis: 0.695 ± 0.533
0.695PheIle: 0.695 ± 0.597
4.17PheLys: 4.17 ± 1.419
2.78PheLeu: 2.78 ± 1.126
2.78PheMet: 2.78 ± 1.126
2.78PheAsn: 2.78 ± 0.352
1.39PhePro: 1.39 ± 0.519
2.78PheGln: 2.78 ± 1.832
4.864PheArg: 4.864 ± 1.967
2.085PheSer: 2.085 ± 0.181
1.39PheThr: 1.39 ± 0.715
2.085PheVal: 2.085 ± 1.03
1.39PheTrp: 1.39 ± 1.194
0.695PheTyr: 0.695 ± 0.533
0.0PheXaa: 0.0 ± 0.0
Gly
2.085GlyAla: 2.085 ± 0.92
0.695GlyCys: 0.695 ± 0.597
2.78GlyAsp: 2.78 ± 0.771
4.864GlyGlu: 4.864 ± 1.074
2.78GlyPhe: 2.78 ± 0.713
8.339GlyGly: 8.339 ± 4.981
0.0GlyHis: 0.0 ± 0.0
2.085GlyIle: 2.085 ± 0.181
5.559GlyLys: 5.559 ± 2.076
2.78GlyLeu: 2.78 ± 1.292
2.085GlyMet: 2.085 ± 0.181
8.339GlyAsn: 8.339 ± 2.208
1.39GlyPro: 1.39 ± 0.519
1.39GlyGln: 1.39 ± 0.519
0.695GlyArg: 0.695 ± 0.65
4.17GlySer: 4.17 ± 1.312
3.475GlyThr: 3.475 ± 0.886
2.78GlyVal: 2.78 ± 1.68
0.695GlyTrp: 0.695 ± 0.65
2.085GlyTyr: 2.085 ± 0.181
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
1.39HisAsp: 1.39 ± 0.563
1.39HisGlu: 1.39 ± 0.563
1.39HisPhe: 1.39 ± 0.519
2.085HisGly: 2.085 ± 0.92
1.39HisHis: 1.39 ± 0.563
2.085HisIle: 2.085 ± 0.828
2.085HisLys: 2.085 ± 0.92
2.085HisLeu: 2.085 ± 0.181
0.695HisMet: 0.695 ± 0.533
2.085HisAsn: 2.085 ± 0.92
1.39HisPro: 1.39 ± 0.563
1.39HisGln: 1.39 ± 0.715
0.695HisArg: 0.695 ± 0.65
0.0HisSer: 0.0 ± 0.0
0.695HisThr: 0.695 ± 0.533
2.085HisVal: 2.085 ± 1.03
0.695HisTrp: 0.695 ± 0.533
0.695HisTyr: 0.695 ± 0.533
0.0HisXaa: 0.0 ± 0.0
Ile
2.78IleAla: 2.78 ± 1.832
0.695IleCys: 0.695 ± 0.533
6.254IleAsp: 6.254 ± 1.483
7.644IleGlu: 7.644 ± 2.771
1.39IlePhe: 1.39 ± 0.715
3.475IleGly: 3.475 ± 1.275
1.39IleHis: 1.39 ± 1.067
3.475IleIle: 3.475 ± 1.795
2.085IleLys: 2.085 ± 0.92
1.39IleLeu: 1.39 ± 1.067
1.39IleMet: 1.39 ± 1.067
3.475IleAsn: 3.475 ± 0.896
2.78IlePro: 2.78 ± 0.352
4.17IleGln: 4.17 ± 1.419
3.475IleArg: 3.475 ± 0.526
4.864IleSer: 4.864 ± 2.091
0.695IleThr: 0.695 ± 0.533
3.475IleVal: 3.475 ± 0.526
0.695IleTrp: 0.695 ± 0.533
1.39IleTyr: 1.39 ± 1.067
0.0IleXaa: 0.0 ± 0.0
Lys
0.695LysAla: 0.695 ± 0.533
2.78LysCys: 2.78 ± 0.713
4.864LysAsp: 4.864 ± 1.123
6.254LysGlu: 6.254 ± 2.831
7.644LysPhe: 7.644 ± 1.222
4.17LysGly: 4.17 ± 2.064
2.085LysHis: 2.085 ± 1.049
4.17LysIle: 4.17 ± 2.419
10.424LysLys: 10.424 ± 2.795
5.559LysLeu: 5.559 ± 0.705
6.254LysMet: 6.254 ± 2.831
4.864LysAsn: 4.864 ± 1.762
1.39LysPro: 1.39 ± 0.563
2.085LysGln: 2.085 ± 1.03
4.864LysArg: 4.864 ± 1.074
2.78LysSer: 2.78 ± 0.771
5.559LysThr: 5.559 ± 2.486
8.339LysVal: 8.339 ± 1.594
1.39LysTrp: 1.39 ± 0.563
4.17LysTyr: 4.17 ± 0.783
0.0LysXaa: 0.0 ± 0.0
Leu
5.559LeuAla: 5.559 ± 3.362
0.695LeuCys: 0.695 ± 0.533
1.39LeuAsp: 1.39 ± 0.563
7.644LeuGlu: 7.644 ± 1.585
2.085LeuPhe: 2.085 ± 0.92
5.559LeuGly: 5.559 ± 1.077
0.695LeuHis: 0.695 ± 0.533
1.39LeuIle: 1.39 ± 1.067
2.085LeuLys: 2.085 ± 0.181
4.17LeuLeu: 4.17 ± 1.104
0.695LeuMet: 0.695 ± 0.65
1.39LeuAsn: 1.39 ± 0.563
2.085LeuPro: 2.085 ± 1.03
3.475LeuGln: 3.475 ± 1.795
2.085LeuArg: 2.085 ± 1.145
2.78LeuSer: 2.78 ± 0.352
4.864LeuThr: 4.864 ± 0.172
5.559LeuVal: 5.559 ± 1.619
2.78LeuTrp: 2.78 ± 1.395
5.559LeuTyr: 5.559 ± 2.336
0.0LeuXaa: 0.0 ± 0.0
Met
2.78MetAla: 2.78 ± 1.68
0.695MetCys: 0.695 ± 0.597
2.085MetAsp: 2.085 ± 1.03
3.475MetGlu: 3.475 ± 1.303
3.475MetPhe: 3.475 ± 2.667
2.085MetGly: 2.085 ± 1.229
0.0MetHis: 0.0 ± 0.0
2.085MetIle: 2.085 ± 0.181
4.17MetLys: 4.17 ± 1.688
2.085MetLeu: 2.085 ± 1.03
2.78MetMet: 2.78 ± 1.395
2.78MetAsn: 2.78 ± 0.713
0.695MetPro: 0.695 ± 0.533
1.39MetGln: 1.39 ± 1.067
1.39MetArg: 1.39 ± 1.067
2.78MetSer: 2.78 ± 0.352
2.085MetThr: 2.085 ± 1.03
0.695MetVal: 0.695 ± 0.533
0.0MetTrp: 0.0 ± 0.0
1.39MetTyr: 1.39 ± 1.067
0.0MetXaa: 0.0 ± 0.0
Asn
3.475AsnAla: 3.475 ± 1.522
1.39AsnCys: 1.39 ± 0.519
2.085AsnAsp: 2.085 ± 1.145
4.864AsnGlu: 4.864 ± 1.232
2.085AsnPhe: 2.085 ± 1.145
2.085AsnGly: 2.085 ± 1.229
0.695AsnHis: 0.695 ± 0.65
7.644AsnIle: 7.644 ± 1.561
6.949AsnLys: 6.949 ± 2.075
4.17AsnLeu: 4.17 ± 0.686
1.39AsnMet: 1.39 ± 0.563
4.17AsnAsn: 4.17 ± 0.363
2.085AsnPro: 2.085 ± 0.92
2.085AsnGln: 2.085 ± 0.181
5.559AsnArg: 5.559 ± 1.165
4.864AsnSer: 4.864 ± 1.953
7.644AsnThr: 7.644 ± 1.258
4.17AsnVal: 4.17 ± 0.686
0.695AsnTrp: 0.695 ± 0.533
2.78AsnTyr: 2.78 ± 1.038
0.0AsnXaa: 0.0 ± 0.0
Pro
2.085ProAla: 2.085 ± 1.229
1.39ProCys: 1.39 ± 1.194
2.085ProAsp: 2.085 ± 0.181
1.39ProGlu: 1.39 ± 0.563
0.0ProPhe: 0.0 ± 0.0
1.39ProGly: 1.39 ± 0.715
1.39ProHis: 1.39 ± 0.519
3.475ProIle: 3.475 ± 0.498
1.39ProLys: 1.39 ± 1.067
2.085ProLeu: 2.085 ± 0.92
1.39ProMet: 1.39 ± 0.519
2.085ProAsn: 2.085 ± 0.181
1.39ProPro: 1.39 ± 0.519
0.0ProGln: 0.0 ± 0.0
0.695ProArg: 0.695 ± 0.597
2.78ProSer: 2.78 ± 0.771
1.39ProThr: 1.39 ± 1.301
2.085ProVal: 2.085 ± 0.828
0.0ProTrp: 0.0 ± 0.0
1.39ProTyr: 1.39 ± 1.194
0.0ProXaa: 0.0 ± 0.0
Gln
2.085GlnAla: 2.085 ± 1.049
0.0GlnCys: 0.0 ± 0.0
2.085GlnAsp: 2.085 ± 0.92
5.559GlnGlu: 5.559 ± 3.362
2.78GlnPhe: 2.78 ± 0.352
2.085GlnGly: 2.085 ± 1.791
1.39GlnHis: 1.39 ± 1.067
1.39GlnIle: 1.39 ± 0.563
2.78GlnLys: 2.78 ± 0.713
4.864GlnLeu: 4.864 ± 0.913
0.695GlnMet: 0.695 ± 0.597
1.39GlnAsn: 1.39 ± 0.519
0.0GlnPro: 0.0 ± 0.0
2.085GlnGln: 2.085 ± 0.181
5.559GlnArg: 5.559 ± 3.333
2.085GlnSer: 2.085 ± 1.049
2.085GlnThr: 2.085 ± 0.181
2.78GlnVal: 2.78 ± 0.352
2.085GlnTrp: 2.085 ± 1.6
0.695GlnTyr: 0.695 ± 0.533
0.0GlnXaa: 0.0 ± 0.0
Arg
3.475ArgAla: 3.475 ± 1.275
0.695ArgCys: 0.695 ± 0.533
4.17ArgAsp: 4.17 ± 1.104
2.78ArgGlu: 2.78 ± 0.771
0.695ArgPhe: 0.695 ± 0.65
2.085ArgGly: 2.085 ± 0.828
2.78ArgHis: 2.78 ± 0.713
2.085ArgIle: 2.085 ± 1.229
4.864ArgLys: 4.864 ± 1.123
2.78ArgLeu: 2.78 ± 0.771
2.085ArgMet: 2.085 ± 0.9
4.17ArgAsn: 4.17 ± 1.394
2.085ArgPro: 2.085 ± 0.828
6.254ArgGln: 6.254 ± 2.185
4.17ArgArg: 4.17 ± 1.394
2.085ArgSer: 2.085 ± 0.181
2.085ArgThr: 2.085 ± 0.92
4.17ArgVal: 4.17 ± 1.104
1.39ArgTrp: 1.39 ± 1.194
0.695ArgTyr: 0.695 ± 0.533
0.0ArgXaa: 0.0 ± 0.0
Ser
4.864SerAla: 4.864 ± 2.018
0.0SerCys: 0.0 ± 0.0
3.475SerAsp: 3.475 ± 0.896
4.17SerGlu: 4.17 ± 1.394
1.39SerPhe: 1.39 ± 0.563
4.864SerGly: 4.864 ± 1.742
2.085SerHis: 2.085 ± 1.03
0.695SerIle: 0.695 ± 0.65
7.644SerLys: 7.644 ± 0.524
3.475SerLeu: 3.475 ± 1.429
2.78SerMet: 2.78 ± 1.275
4.864SerAsn: 4.864 ± 1.123
2.085SerPro: 2.085 ± 0.181
1.39SerGln: 1.39 ± 1.194
2.78SerArg: 2.78 ± 1.292
5.559SerSer: 5.559 ± 0.705
4.864SerThr: 4.864 ± 1.742
2.085SerVal: 2.085 ± 0.181
0.695SerTrp: 0.695 ± 0.65
1.39SerTyr: 1.39 ± 1.194
0.0SerXaa: 0.0 ± 0.0
Thr
4.864ThrAla: 4.864 ± 1.742
0.0ThrCys: 0.0 ± 0.0
0.695ThrAsp: 0.695 ± 0.533
2.78ThrGlu: 2.78 ± 0.713
2.085ThrPhe: 2.085 ± 0.828
2.085ThrGly: 2.085 ± 1.03
0.695ThrHis: 0.695 ± 0.533
3.475ThrIle: 3.475 ± 1.901
1.39ThrLys: 1.39 ± 0.563
2.085ThrLeu: 2.085 ± 0.181
2.085ThrMet: 2.085 ± 0.181
6.254ThrAsn: 6.254 ± 1.515
2.085ThrPro: 2.085 ± 1.229
6.254ThrGln: 6.254 ± 0.568
2.78ThrArg: 2.78 ± 2.602
4.17ThrSer: 4.17 ± 1.394
0.695ThrThr: 0.695 ± 0.597
2.78ThrVal: 2.78 ± 0.352
1.39ThrTrp: 1.39 ± 0.519
2.085ThrTyr: 2.085 ± 0.828
0.0ThrXaa: 0.0 ± 0.0
Val
2.085ValAla: 2.085 ± 1.229
1.39ValCys: 1.39 ± 0.563
2.085ValAsp: 2.085 ± 0.92
3.475ValGlu: 3.475 ± 0.498
2.78ValPhe: 2.78 ± 1.587
1.39ValGly: 1.39 ± 1.067
3.475ValHis: 3.475 ± 1.429
2.78ValIle: 2.78 ± 0.713
7.644ValLys: 7.644 ± 0.626
2.78ValLeu: 2.78 ± 1.395
1.39ValMet: 1.39 ± 0.563
4.864ValAsn: 4.864 ± 1.967
0.695ValPro: 0.695 ± 0.597
2.085ValGln: 2.085 ± 1.049
4.864ValArg: 4.864 ± 1.982
2.78ValSer: 2.78 ± 1.126
3.475ValThr: 3.475 ± 0.498
2.085ValVal: 2.085 ± 0.181
1.39ValTrp: 1.39 ± 0.715
2.085ValTyr: 2.085 ± 1.951
0.0ValXaa: 0.0 ± 0.0
Trp
0.695TrpAla: 0.695 ± 0.65
0.0TrpCys: 0.0 ± 0.0
0.695TrpAsp: 0.695 ± 0.533
1.39TrpGlu: 1.39 ± 0.563
0.0TrpPhe: 0.0 ± 0.0
0.695TrpGly: 0.695 ± 0.65
0.0TrpHis: 0.0 ± 0.0
2.085TrpIle: 2.085 ± 0.92
1.39TrpLys: 1.39 ± 0.519
1.39TrpLeu: 1.39 ± 0.563
0.695TrpMet: 0.695 ± 0.661
2.085TrpAsn: 2.085 ± 0.92
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
0.695TrpArg: 0.695 ± 0.597
2.78TrpSer: 2.78 ± 0.713
0.0TrpThr: 0.0 ± 0.0
0.695TrpVal: 0.695 ± 0.533
0.0TrpTrp: 0.0 ± 0.0
1.39TrpTyr: 1.39 ± 1.067
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.39TyrAla: 1.39 ± 0.519
0.0TyrCys: 0.0 ± 0.0
2.085TyrAsp: 2.085 ± 1.6
2.085TyrGlu: 2.085 ± 0.92
2.085TyrPhe: 2.085 ± 1.145
3.475TyrGly: 3.475 ± 0.526
0.0TyrHis: 0.0 ± 0.0
4.864TyrIle: 4.864 ± 0.172
4.864TyrLys: 4.864 ± 1.123
2.085TyrLeu: 2.085 ± 0.92
4.17TyrMet: 4.17 ± 2.419
0.695TyrAsn: 0.695 ± 0.597
0.695TyrPro: 0.695 ± 0.597
0.0TyrGln: 0.0 ± 0.0
0.695TyrArg: 0.695 ± 0.597
2.78TyrSer: 2.78 ± 1.395
1.39TyrThr: 1.39 ± 0.519
2.78TyrVal: 2.78 ± 0.713
0.695TyrTrp: 0.695 ± 0.533
4.864TyrTyr: 4.864 ± 2.091
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1440 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski