Amino acid dipepetide frequency for Infectious hypodermal and hematopoietic necrosis virus (IHHNV) (Decapod penstyldensovirus 1)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.211AlaAla: 2.211 ± 1.286
0.0AlaCys: 0.0 ± 0.0
4.422AlaAsp: 4.422 ± 2.572
5.158AlaGlu: 5.158 ± 0.743
0.737AlaPhe: 0.737 ± 0.719
0.737AlaGly: 0.737 ± 0.772
0.737AlaHis: 0.737 ± 0.772
1.474AlaIle: 1.474 ± 0.541
1.474AlaLys: 1.474 ± 0.596
2.211AlaLeu: 2.211 ± 1.501
0.737AlaMet: 0.737 ± 0.719
2.948AlaAsn: 2.948 ± 1.156
0.737AlaPro: 0.737 ± 0.772
0.0AlaGln: 0.0 ± 0.0
2.948AlaArg: 2.948 ± 1.082
1.474AlaSer: 1.474 ± 1.544
2.948AlaThr: 2.948 ± 0.067
1.474AlaVal: 1.474 ± 0.541
1.474AlaTrp: 1.474 ± 0.541
1.474AlaTyr: 1.474 ± 0.596
0.0AlaXaa: 0.0 ± 0.0
Cys
0.737CysAla: 0.737 ± 0.772
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.737CysPhe: 0.737 ± 0.719
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.737CysIle: 0.737 ± 0.719
0.0CysLys: 0.0 ± 0.0
2.211CysLeu: 2.211 ± 1.594
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.737CysPro: 0.737 ± 0.5
0.0CysGln: 0.0 ± 0.0
0.737CysArg: 0.737 ± 0.772
1.474CysSer: 1.474 ± 0.541
1.474CysThr: 1.474 ± 0.596
1.474CysVal: 1.474 ± 0.596
0.0CysTrp: 0.0 ± 0.0
0.737CysTyr: 0.737 ± 0.772
0.0CysXaa: 0.0 ± 0.0
Asp
2.211AspAla: 2.211 ± 1.286
0.0AspCys: 0.0 ± 0.0
4.422AspAsp: 4.422 ± 2.099
5.895AspGlu: 5.895 ± 1.233
2.948AspPhe: 2.948 ± 1.173
5.158AspGly: 5.158 ± 0.851
2.948AspHis: 2.948 ± 1.173
5.158AspIle: 5.158 ± 1.893
4.422AspLys: 4.422 ± 2.098
1.474AspLeu: 1.474 ± 0.596
0.0AspMet: 0.0 ± 0.0
3.685AspAsn: 3.685 ± 2.502
2.948AspPro: 2.948 ± 1.193
0.737AspGln: 0.737 ± 0.719
4.422AspArg: 4.422 ± 0.489
5.158AspSer: 5.158 ± 1.585
4.422AspThr: 4.422 ± 2.045
0.737AspVal: 0.737 ± 0.772
2.211AspTrp: 2.211 ± 1.518
2.211AspTyr: 2.211 ± 1.501
0.0AspXaa: 0.0 ± 0.0
Glu
2.948GluAla: 2.948 ± 0.067
0.0GluCys: 0.0 ± 0.0
4.422GluAsp: 4.422 ± 0.654
8.106GluGlu: 8.106 ± 1.682
2.211GluPhe: 2.211 ± 1.518
4.422GluGly: 4.422 ± 1.038
1.474GluHis: 1.474 ± 0.966
6.632GluIle: 6.632 ± 0.587
3.685GluLys: 3.685 ± 1.62
5.895GluLeu: 5.895 ± 1.798
0.737GluMet: 0.737 ± 0.5
2.211GluAsn: 2.211 ± 0.755
3.685GluPro: 3.685 ± 1.214
3.685GluGln: 3.685 ± 0.653
3.685GluArg: 3.685 ± 1.675
5.895GluSer: 5.895 ± 3.076
7.369GluThr: 7.369 ± 2.387
2.948GluVal: 2.948 ± 1.056
0.0GluTrp: 0.0 ± 0.0
2.211GluTyr: 2.211 ± 1.501
0.0GluXaa: 0.0 ± 0.0
Phe
0.737PheAla: 0.737 ± 0.5
0.0PheCys: 0.0 ± 0.0
1.474PheAsp: 1.474 ± 1.544
4.422PheGlu: 4.422 ± 0.935
0.737PhePhe: 0.737 ± 0.772
1.474PheGly: 1.474 ± 0.596
1.474PheHis: 1.474 ± 1.001
2.211PheIle: 2.211 ± 0.785
2.211PheLys: 2.211 ± 0.785
3.685PheLeu: 3.685 ± 1.745
1.474PheMet: 1.474 ± 1.544
2.211PheAsn: 2.211 ± 0.467
0.0PhePro: 0.0 ± 0.0
3.685PheGln: 3.685 ± 0.54
0.737PheArg: 0.737 ± 0.719
1.474PheSer: 1.474 ± 0.541
1.474PheThr: 1.474 ± 0.596
0.737PheVal: 0.737 ± 0.5
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
0.737GlyAla: 0.737 ± 0.5
2.211GlyCys: 2.211 ± 1.286
5.895GlyAsp: 5.895 ± 2.068
2.211GlyGlu: 2.211 ± 0.785
1.474GlyPhe: 1.474 ± 0.966
4.422GlyGly: 4.422 ± 1.789
1.474GlyHis: 1.474 ± 1.001
3.685GlyIle: 3.685 ± 2.502
4.422GlyLys: 4.422 ± 2.098
5.158GlyLeu: 5.158 ± 0.851
0.737GlyMet: 0.737 ± 0.772
3.685GlyAsn: 3.685 ± 1.301
5.158GlyPro: 5.158 ± 1.866
2.948GlyGln: 2.948 ± 1.156
2.211GlyArg: 2.211 ± 1.501
4.422GlySer: 4.422 ± 2.098
6.632GlyThr: 6.632 ± 1.637
2.211GlyVal: 2.211 ± 0.467
0.737GlyTrp: 0.737 ± 0.772
0.737GlyTyr: 0.737 ± 0.719
0.0GlyXaa: 0.0 ± 0.0
His
2.211HisAla: 2.211 ± 1.286
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
2.948HisGly: 2.948 ± 0.067
1.474HisHis: 1.474 ± 0.966
2.211HisIle: 2.211 ± 0.467
0.737HisLys: 0.737 ± 0.772
3.685HisLeu: 3.685 ± 0.54
0.0HisMet: 0.0 ± 0.0
2.948HisAsn: 2.948 ± 1.932
0.737HisPro: 0.737 ± 0.5
2.948HisGln: 2.948 ± 1.082
2.211HisArg: 2.211 ± 0.785
1.474HisSer: 1.474 ± 0.596
2.948HisThr: 2.948 ± 1.156
1.474HisVal: 1.474 ± 0.541
1.474HisTrp: 1.474 ± 0.596
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.737IleCys: 0.737 ± 0.719
3.685IleAsp: 3.685 ± 1.62
2.948IleGlu: 2.948 ± 1.082
2.948IlePhe: 2.948 ± 1.193
1.474IleGly: 1.474 ± 1.001
2.211IleHis: 2.211 ± 1.594
2.948IleIle: 2.948 ± 2.001
5.895IleLys: 5.895 ± 1.169
5.895IleLeu: 5.895 ± 1.948
2.948IleMet: 2.948 ± 1.056
2.211IleAsn: 2.211 ± 0.755
3.685IlePro: 3.685 ± 1.433
2.948IleGln: 2.948 ± 1.193
4.422IleArg: 4.422 ± 1.509
4.422IleSer: 4.422 ± 2.099
5.895IleThr: 5.895 ± 2.038
0.737IleVal: 0.737 ± 0.5
2.211IleTrp: 2.211 ± 2.156
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
2.948LysAla: 2.948 ± 1.156
0.737LysCys: 0.737 ± 0.772
3.685LysAsp: 3.685 ± 1.301
4.422LysGlu: 4.422 ± 1.038
0.0LysPhe: 0.0 ± 0.0
2.211LysGly: 2.211 ± 0.467
0.737LysHis: 0.737 ± 0.5
3.685LysIle: 3.685 ± 1.214
2.948LysLys: 2.948 ± 2.001
7.369LysLeu: 7.369 ± 1.57
0.737LysMet: 0.737 ± 0.772
2.948LysAsn: 2.948 ± 2.169
5.158LysPro: 5.158 ± 1.538
1.474LysGln: 1.474 ± 1.001
7.369LysArg: 7.369 ± 1.57
5.158LysSer: 5.158 ± 1.933
5.158LysThr: 5.158 ± 1.104
2.948LysVal: 2.948 ± 1.156
3.685LysTrp: 3.685 ± 2.521
1.474LysTyr: 1.474 ± 1.001
0.0LysXaa: 0.0 ± 0.0
Leu
3.685LeuAla: 3.685 ± 0.54
0.0LeuCys: 0.0 ± 0.0
1.474LeuAsp: 1.474 ± 1.001
6.632LeuGlu: 6.632 ± 1.682
2.948LeuPhe: 2.948 ± 2.001
8.106LeuGly: 8.106 ± 3.1
3.685LeuHis: 3.685 ± 2.798
4.422LeuIle: 4.422 ± 1.623
5.895LeuLys: 5.895 ± 3.864
7.369LeuLeu: 7.369 ± 2.706
0.737LeuMet: 0.737 ± 0.772
4.422LeuAsn: 4.422 ± 1.372
5.158LeuPro: 5.158 ± 3.675
8.843LeuGln: 8.843 ± 1.732
2.948LeuArg: 2.948 ± 1.082
5.158LeuSer: 5.158 ± 1.538
5.158LeuThr: 5.158 ± 0.743
6.632LeuVal: 6.632 ± 0.584
0.737LeuTrp: 0.737 ± 0.5
2.948LeuTyr: 2.948 ± 2.036
0.0LeuXaa: 0.0 ± 0.0
Met
0.737MetAla: 0.737 ± 0.5
0.737MetCys: 0.737 ± 0.772
0.737MetAsp: 0.737 ± 0.5
2.948MetGlu: 2.948 ± 2.169
0.0MetPhe: 0.0 ± 0.0
0.737MetGly: 0.737 ± 0.5
1.474MetHis: 1.474 ± 1.544
0.0MetIle: 0.0 ± 0.0
1.474MetLys: 1.474 ± 1.544
1.474MetLeu: 1.474 ± 0.596
0.737MetMet: 0.737 ± 0.772
1.474MetAsn: 1.474 ± 0.596
0.0MetPro: 0.0 ± 0.0
0.737MetGln: 0.737 ± 0.5
1.474MetArg: 1.474 ± 1.544
2.211MetSer: 2.211 ± 0.467
2.211MetThr: 2.211 ± 1.17
2.211MetVal: 2.211 ± 1.594
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
0.737AsnAla: 0.737 ± 0.719
1.474AsnCys: 1.474 ± 1.438
2.948AsnAsp: 2.948 ± 1.193
2.211AsnGlu: 2.211 ± 0.467
2.211AsnPhe: 2.211 ± 0.467
4.422AsnGly: 4.422 ± 0.489
2.211AsnHis: 2.211 ± 1.17
2.211AsnIle: 2.211 ± 1.501
6.632AsnLys: 6.632 ± 1.637
6.632AsnLeu: 6.632 ± 0.822
2.211AsnMet: 2.211 ± 0.826
2.948AsnAsn: 2.948 ± 1.082
2.948AsnPro: 2.948 ± 1.056
4.422AsnGln: 4.422 ± 1.372
1.474AsnArg: 1.474 ± 1.001
3.685AsnSer: 3.685 ± 2.502
5.895AsnThr: 5.895 ± 1.029
0.0AsnVal: 0.0 ± 0.0
0.737AsnTrp: 0.737 ± 0.772
0.737AsnTyr: 0.737 ± 0.772
0.0AsnXaa: 0.0 ± 0.0
Pro
2.211ProAla: 2.211 ± 0.467
1.474ProCys: 1.474 ± 0.596
6.632ProAsp: 6.632 ± 1.612
3.685ProGlu: 3.685 ± 1.214
0.737ProPhe: 0.737 ± 0.719
0.737ProGly: 0.737 ± 0.5
1.474ProHis: 1.474 ± 0.596
3.685ProIle: 3.685 ± 1.433
4.422ProLys: 4.422 ± 1.038
4.422ProLeu: 4.422 ± 3.035
0.737ProMet: 0.737 ± 0.719
3.685ProAsn: 3.685 ± 0.54
5.158ProPro: 5.158 ± 0.743
3.685ProGln: 3.685 ± 1.433
3.685ProArg: 3.685 ± 0.54
2.211ProSer: 2.211 ± 0.467
7.369ProThr: 7.369 ± 1.306
0.0ProVal: 0.0 ± 0.0
0.0ProTrp: 0.0 ± 0.0
1.474ProTyr: 1.474 ± 0.596
0.0ProXaa: 0.0 ± 0.0
Gln
2.211GlnAla: 2.211 ± 1.518
0.0GlnCys: 0.0 ± 0.0
0.737GlnAsp: 0.737 ± 0.5
5.895GlnGlu: 5.895 ± 1.948
2.948GlnPhe: 2.948 ± 1.156
2.948GlnGly: 2.948 ± 1.173
2.211GlnHis: 2.211 ± 1.17
4.422GlnIle: 4.422 ± 1.372
2.211GlnLys: 2.211 ± 2.156
5.895GlnLeu: 5.895 ± 2.386
2.211GlnMet: 2.211 ± 1.321
3.685GlnAsn: 3.685 ± 0.653
2.211GlnPro: 2.211 ± 0.755
2.211GlnGln: 2.211 ± 1.286
1.474GlnArg: 1.474 ± 0.596
2.211GlnSer: 2.211 ± 0.467
4.422GlnThr: 4.422 ± 0.489
1.474GlnVal: 1.474 ± 0.541
0.737GlnTrp: 0.737 ± 0.5
2.948GlnTyr: 2.948 ± 1.173
0.0GlnXaa: 0.0 ± 0.0
Arg
4.422ArgAla: 4.422 ± 0.489
0.737ArgCys: 0.737 ± 0.772
2.948ArgAsp: 2.948 ± 1.056
5.158ArgGlu: 5.158 ± 1.722
0.737ArgPhe: 0.737 ± 0.5
2.948ArgGly: 2.948 ± 2.001
1.474ArgHis: 1.474 ± 1.001
2.948ArgIle: 2.948 ± 1.161
3.685ArgLys: 3.685 ± 1.433
5.158ArgLeu: 5.158 ± 0.743
1.474ArgMet: 1.474 ± 0.596
2.948ArgAsn: 2.948 ± 1.173
0.737ArgPro: 0.737 ± 0.719
3.685ArgGln: 3.685 ± 1.214
5.158ArgArg: 5.158 ± 1.933
1.474ArgSer: 1.474 ± 0.966
8.843ArgThr: 8.843 ± 2.328
2.211ArgVal: 2.211 ± 0.467
0.737ArgTrp: 0.737 ± 0.5
2.948ArgTyr: 2.948 ± 1.156
0.0ArgXaa: 0.0 ± 0.0
Ser
2.948SerAla: 2.948 ± 0.067
0.737SerCys: 0.737 ± 0.5
7.369SerAsp: 7.369 ± 3.039
5.158SerGlu: 5.158 ± 2.585
1.474SerPhe: 1.474 ± 0.966
4.422SerGly: 4.422 ± 1.57
0.737SerHis: 0.737 ± 0.719
1.474SerIle: 1.474 ± 0.966
1.474SerLys: 1.474 ± 1.001
5.158SerLeu: 5.158 ± 1.933
1.474SerMet: 1.474 ± 1.544
5.158SerAsn: 5.158 ± 1.893
5.158SerPro: 5.158 ± 2.566
3.685SerGln: 3.685 ± 2.502
1.474SerArg: 1.474 ± 0.966
8.106SerSer: 8.106 ± 2.512
5.158SerThr: 5.158 ± 1.325
2.211SerVal: 2.211 ± 1.17
0.0SerTrp: 0.0 ± 0.0
1.474SerTyr: 1.474 ± 1.001
0.0SerXaa: 0.0 ± 0.0
Thr
0.737ThrAla: 0.737 ± 0.772
0.0ThrCys: 0.0 ± 0.0
5.158ThrAsp: 5.158 ± 1.104
3.685ThrGlu: 3.685 ± 1.745
5.158ThrPhe: 5.158 ± 1.866
9.58ThrGly: 9.58 ± 1.942
1.474ThrHis: 1.474 ± 0.541
3.685ThrIle: 3.685 ± 1.624
6.632ThrLys: 6.632 ± 2.506
4.422ThrLeu: 4.422 ± 1.95
0.0ThrMet: 0.0 ± 0.422
4.422ThrAsn: 4.422 ± 1.57
9.58ThrPro: 9.58 ± 2.667
2.948ThrGln: 2.948 ± 1.056
9.58ThrArg: 9.58 ± 2.846
6.632ThrSer: 6.632 ± 1.612
8.843ThrThr: 8.843 ± 0.977
5.158ThrVal: 5.158 ± 1.104
1.474ThrTrp: 1.474 ± 0.541
3.685ThrTyr: 3.685 ± 0.54
0.0ThrXaa: 0.0 ± 0.0
Val
2.211ValAla: 2.211 ± 0.467
0.737ValCys: 0.737 ± 0.5
2.211ValAsp: 2.211 ± 1.501
0.737ValGlu: 0.737 ± 0.5
0.0ValPhe: 0.0 ± 0.0
0.737ValGly: 0.737 ± 0.5
1.474ValHis: 1.474 ± 0.966
1.474ValIle: 1.474 ± 0.541
2.211ValLys: 2.211 ± 0.467
3.685ValLeu: 3.685 ± 1.675
1.474ValMet: 1.474 ± 0.966
3.685ValAsn: 3.685 ± 1.675
2.211ValPro: 2.211 ± 0.785
3.685ValGln: 3.685 ± 1.433
3.685ValArg: 3.685 ± 0.653
0.737ValSer: 0.737 ± 0.772
4.422ValThr: 4.422 ± 0.935
1.474ValVal: 1.474 ± 0.966
0.0ValTrp: 0.0 ± 0.0
0.737ValTyr: 0.737 ± 0.772
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
0.737TrpAsp: 0.737 ± 0.772
1.474TrpGlu: 1.474 ± 1.438
0.0TrpPhe: 0.0 ± 0.0
0.737TrpGly: 0.737 ± 0.772
0.737TrpHis: 0.737 ± 0.5
3.685TrpIle: 3.685 ± 0.54
2.211TrpLys: 2.211 ± 1.518
0.0TrpLeu: 0.0 ± 0.0
0.737TrpMet: 0.737 ± 0.772
0.737TrpAsn: 0.737 ± 0.719
0.737TrpPro: 0.737 ± 0.719
0.737TrpGln: 0.737 ± 0.772
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
1.474TrpThr: 1.474 ± 0.541
1.474TrpVal: 1.474 ± 0.541
0.0TrpTrp: 0.0 ± 0.0
1.474TrpTyr: 1.474 ± 0.596
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.737TyrAla: 0.737 ± 0.5
1.474TyrCys: 1.474 ± 0.966
2.211TyrAsp: 2.211 ± 1.501
1.474TyrGlu: 1.474 ± 0.596
2.211TyrPhe: 2.211 ± 0.785
2.948TyrGly: 2.948 ± 2.036
0.0TyrHis: 0.0 ± 0.0
1.474TyrIle: 1.474 ± 0.596
2.211TyrLys: 2.211 ± 0.785
5.158TyrLeu: 5.158 ± 1.325
1.474TyrMet: 1.474 ± 1.001
0.737TyrAsn: 0.737 ± 0.5
0.737TyrPro: 0.737 ± 0.772
0.0TyrGln: 0.0 ± 0.0
0.737TyrArg: 0.737 ± 0.5
1.474TyrSer: 1.474 ± 0.541
1.474TyrThr: 1.474 ± 0.596
0.0TyrVal: 0.0 ± 0.0
0.737TyrTrp: 0.737 ± 0.5
0.737TyrTyr: 0.737 ± 0.5
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1358 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski