Amino acid dipepetide frequency for Hubei sobemo-like virus 36

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.478AlaAla: 2.478 ± 1.728
0.0AlaCys: 0.0 ± 0.0
2.478AlaAsp: 2.478 ± 0.039
2.478AlaGlu: 2.478 ± 0.039
0.0AlaPhe: 0.0 ± 0.0
3.717AlaGly: 3.717 ± 0.943
0.0AlaHis: 0.0 ± 0.0
1.239AlaIle: 1.239 ± 0.864
1.239AlaLys: 1.239 ± 0.903
2.478AlaLeu: 2.478 ± 0.039
3.717AlaMet: 3.717 ± 0.943
6.196AlaAsn: 6.196 ± 0.785
2.478AlaPro: 2.478 ± 1.728
2.478AlaGln: 2.478 ± 1.728
3.717AlaArg: 3.717 ± 0.824
3.717AlaSer: 3.717 ± 0.824
2.478AlaThr: 2.478 ± 1.807
4.957AlaVal: 4.957 ± 1.688
0.0AlaTrp: 0.0 ± 0.0
3.717AlaTyr: 3.717 ± 0.943
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
1.239CysAsp: 1.239 ± 0.864
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.239CysIle: 1.239 ± 0.903
0.0CysLys: 0.0 ± 0.0
1.239CysLeu: 1.239 ± 0.864
0.0CysMet: 0.0 ± 0.0
1.239CysAsn: 1.239 ± 0.903
0.0CysPro: 0.0 ± 0.0
1.239CysGln: 1.239 ± 0.903
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.239CysVal: 1.239 ± 0.903
0.0CysTrp: 0.0 ± 0.0
1.239CysTyr: 1.239 ± 0.864
0.0CysXaa: 0.0 ± 0.0
Asp
0.0AspAla: 0.0 ± 0.0
0.0AspCys: 0.0 ± 0.0
6.196AspAsp: 6.196 ± 0.982
3.717AspGlu: 3.717 ± 2.592
2.478AspPhe: 2.478 ± 1.807
1.239AspGly: 1.239 ± 0.864
1.239AspHis: 1.239 ± 0.903
4.957AspIle: 4.957 ± 1.688
4.957AspLys: 4.957 ± 0.079
12.392AspLeu: 12.392 ± 0.197
0.0AspMet: 0.0 ± 0.0
1.239AspAsn: 1.239 ± 0.903
1.239AspPro: 1.239 ± 0.903
1.239AspGln: 1.239 ± 0.903
1.239AspArg: 1.239 ± 0.864
4.957AspSer: 4.957 ± 0.079
0.0AspThr: 0.0 ± 0.0
4.957AspVal: 4.957 ± 1.846
1.239AspTrp: 1.239 ± 0.903
2.478AspTyr: 2.478 ± 1.807
0.0AspXaa: 0.0 ± 0.0
Glu
1.239GluAla: 1.239 ± 0.864
0.0GluCys: 0.0 ± 0.0
3.717GluAsp: 3.717 ± 0.943
3.717GluGlu: 3.717 ± 0.824
3.717GluPhe: 3.717 ± 0.824
3.717GluGly: 3.717 ± 2.592
0.0GluHis: 0.0 ± 0.0
4.957GluIle: 4.957 ± 0.079
4.957GluLys: 4.957 ± 0.079
4.957GluLeu: 4.957 ± 1.846
0.0GluMet: 0.0 ± 0.0
3.717GluAsn: 3.717 ± 0.824
3.717GluPro: 3.717 ± 2.71
2.478GluGln: 2.478 ± 0.039
2.478GluArg: 2.478 ± 0.039
7.435GluSer: 7.435 ± 3.416
2.478GluThr: 2.478 ± 1.807
1.239GluVal: 1.239 ± 0.864
1.239GluTrp: 1.239 ± 0.903
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.478PheAla: 2.478 ± 1.807
0.0PheCys: 0.0 ± 0.0
1.239PheAsp: 1.239 ± 0.903
2.478PheGlu: 2.478 ± 1.728
0.0PhePhe: 0.0 ± 0.0
1.239PheGly: 1.239 ± 0.903
1.239PheHis: 1.239 ± 0.903
2.478PheIle: 2.478 ± 1.807
1.239PheLys: 1.239 ± 0.864
3.717PheLeu: 3.717 ± 0.943
0.0PheMet: 0.0 ± 0.0
2.478PheAsn: 2.478 ± 1.807
2.478PhePro: 2.478 ± 0.039
1.239PheGln: 1.239 ± 0.864
2.478PheArg: 2.478 ± 0.039
3.717PheSer: 3.717 ± 0.824
1.239PheThr: 1.239 ± 0.903
2.478PheVal: 2.478 ± 1.728
0.0PheTrp: 0.0 ± 0.0
1.239PheTyr: 1.239 ± 0.903
0.0PheXaa: 0.0 ± 0.0
Gly
6.196GlyAla: 6.196 ± 4.32
1.239GlyCys: 1.239 ± 0.903
1.239GlyAsp: 1.239 ± 0.903
1.239GlyGlu: 1.239 ± 0.903
1.239GlyPhe: 1.239 ± 0.864
1.239GlyGly: 1.239 ± 0.903
1.239GlyHis: 1.239 ± 0.864
4.957GlyIle: 4.957 ± 0.079
4.957GlyLys: 4.957 ± 1.688
1.239GlyLeu: 1.239 ± 0.864
4.957GlyMet: 4.957 ± 1.688
2.478GlyAsn: 2.478 ± 1.728
2.478GlyPro: 2.478 ± 1.728
2.478GlyGln: 2.478 ± 1.728
1.239GlyArg: 1.239 ± 0.864
7.435GlySer: 7.435 ± 3.416
0.0GlyThr: 0.0 ± 0.0
1.239GlyVal: 1.239 ± 0.864
2.478GlyTrp: 2.478 ± 1.807
4.957GlyTyr: 4.957 ± 1.846
0.0GlyXaa: 0.0 ± 0.0
His
1.239HisAla: 1.239 ± 0.903
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
1.239HisPhe: 1.239 ± 0.903
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
3.717HisIle: 3.717 ± 0.824
1.239HisLys: 1.239 ± 0.903
1.239HisLeu: 1.239 ± 0.903
3.717HisMet: 3.717 ± 0.943
0.0HisAsn: 0.0 ± 0.0
1.239HisPro: 1.239 ± 0.903
2.478HisGln: 2.478 ± 0.039
1.239HisArg: 1.239 ± 0.903
1.239HisSer: 1.239 ± 0.864
0.0HisThr: 0.0 ± 0.0
4.957HisVal: 4.957 ± 1.688
0.0HisTrp: 0.0 ± 0.0
1.239HisTyr: 1.239 ± 0.903
0.0HisXaa: 0.0 ± 0.0
Ile
2.478IleAla: 2.478 ± 0.039
0.0IleCys: 0.0 ± 0.0
2.478IleAsp: 2.478 ± 1.807
1.239IleGlu: 1.239 ± 0.864
1.239IlePhe: 1.239 ± 0.864
3.717IleGly: 3.717 ± 2.592
2.478IleHis: 2.478 ± 0.039
4.957IleIle: 4.957 ± 3.613
3.717IleLys: 3.717 ± 0.943
4.957IleLeu: 4.957 ± 0.079
1.239IleMet: 1.239 ± 0.903
1.239IleAsn: 1.239 ± 0.903
2.478IlePro: 2.478 ± 0.039
3.717IleGln: 3.717 ± 2.71
3.717IleArg: 3.717 ± 2.71
9.913IleSer: 9.913 ± 3.692
3.717IleThr: 3.717 ± 0.824
2.478IleVal: 2.478 ± 0.039
1.239IleTrp: 1.239 ± 0.903
3.717IleTyr: 3.717 ± 2.592
0.0IleXaa: 0.0 ± 0.0
Lys
4.957LysAla: 4.957 ± 1.688
1.239LysCys: 1.239 ± 0.864
2.478LysAsp: 2.478 ± 1.807
4.957LysGlu: 4.957 ± 1.688
1.239LysPhe: 1.239 ± 0.864
2.478LysGly: 2.478 ± 1.728
2.478LysHis: 2.478 ± 0.039
2.478LysIle: 2.478 ± 1.807
3.717LysLys: 3.717 ± 0.824
8.674LysLeu: 8.674 ± 0.746
1.239LysMet: 1.239 ± 0.61
3.717LysAsn: 3.717 ± 0.824
7.435LysPro: 7.435 ± 1.649
2.478LysGln: 2.478 ± 0.039
3.717LysArg: 3.717 ± 2.71
7.435LysSer: 7.435 ± 1.649
4.957LysThr: 4.957 ± 1.846
6.196LysVal: 6.196 ± 0.982
2.478LysTrp: 2.478 ± 0.039
2.478LysTyr: 2.478 ± 1.728
0.0LysXaa: 0.0 ± 0.0
Leu
3.717LeuAla: 3.717 ± 0.824
2.478LeuCys: 2.478 ± 0.039
7.435LeuAsp: 7.435 ± 1.886
7.435LeuGlu: 7.435 ± 0.118
4.957LeuPhe: 4.957 ± 3.613
2.478LeuGly: 2.478 ± 0.039
2.478LeuHis: 2.478 ± 0.039
4.957LeuIle: 4.957 ± 0.079
8.674LeuLys: 8.674 ± 0.746
6.196LeuLeu: 6.196 ± 2.749
1.239LeuMet: 1.239 ± 0.864
6.196LeuAsn: 6.196 ± 0.982
2.478LeuPro: 2.478 ± 1.728
4.957LeuGln: 4.957 ± 1.688
3.717LeuArg: 3.717 ± 0.824
4.957LeuSer: 4.957 ± 1.688
2.478LeuThr: 2.478 ± 0.039
6.196LeuVal: 6.196 ± 0.982
3.717LeuTrp: 3.717 ± 0.943
2.478LeuTyr: 2.478 ± 1.807
0.0LeuXaa: 0.0 ± 0.0
Met
1.239MetAla: 1.239 ± 0.903
0.0MetCys: 0.0 ± 0.0
1.239MetAsp: 1.239 ± 0.903
2.478MetGlu: 2.478 ± 1.728
1.239MetPhe: 1.239 ± 0.903
2.478MetGly: 2.478 ± 0.039
1.239MetHis: 1.239 ± 0.864
2.478MetIle: 2.478 ± 1.728
2.478MetLys: 2.478 ± 1.807
2.478MetLeu: 2.478 ± 1.807
1.239MetMet: 1.239 ± 0.864
1.239MetAsn: 1.239 ± 0.864
1.239MetPro: 1.239 ± 0.864
0.0MetGln: 0.0 ± 0.0
2.478MetArg: 2.478 ± 1.807
0.0MetSer: 0.0 ± 0.0
0.0MetThr: 0.0 ± 0.0
2.478MetVal: 2.478 ± 0.039
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.478AsnAla: 2.478 ± 0.039
1.239AsnCys: 1.239 ± 0.903
1.239AsnAsp: 1.239 ± 0.864
3.717AsnGlu: 3.717 ± 0.824
1.239AsnPhe: 1.239 ± 0.903
4.957AsnGly: 4.957 ± 1.688
2.478AsnHis: 2.478 ± 0.039
3.717AsnIle: 3.717 ± 0.943
3.717AsnLys: 3.717 ± 0.824
4.957AsnLeu: 4.957 ± 3.456
1.239AsnMet: 1.239 ± 0.864
1.239AsnAsn: 1.239 ± 0.903
1.239AsnPro: 1.239 ± 0.903
4.957AsnGln: 4.957 ± 0.079
3.717AsnArg: 3.717 ± 0.824
3.717AsnSer: 3.717 ± 0.943
1.239AsnThr: 1.239 ± 0.903
3.717AsnVal: 3.717 ± 0.943
0.0AsnTrp: 0.0 ± 0.0
1.239AsnTyr: 1.239 ± 0.903
0.0AsnXaa: 0.0 ± 0.0
Pro
1.239ProAla: 1.239 ± 0.903
0.0ProCys: 0.0 ± 0.0
2.478ProAsp: 2.478 ± 1.728
7.435ProGlu: 7.435 ± 1.886
1.239ProPhe: 1.239 ± 0.903
4.957ProGly: 4.957 ± 1.688
1.239ProHis: 1.239 ± 0.903
3.717ProIle: 3.717 ± 2.71
3.717ProLys: 3.717 ± 2.592
3.717ProLeu: 3.717 ± 0.943
1.239ProMet: 1.239 ± 0.864
1.239ProAsn: 1.239 ± 0.864
2.478ProPro: 2.478 ± 1.728
2.478ProGln: 2.478 ± 1.728
1.239ProArg: 1.239 ± 0.903
2.478ProSer: 2.478 ± 1.728
0.0ProThr: 0.0 ± 0.0
3.717ProVal: 3.717 ± 0.824
1.239ProTrp: 1.239 ± 0.903
2.478ProTyr: 2.478 ± 1.807
0.0ProXaa: 0.0 ± 0.0
Gln
1.239GlnAla: 1.239 ± 0.864
1.239GlnCys: 1.239 ± 0.864
0.0GlnAsp: 0.0 ± 0.0
2.478GlnGlu: 2.478 ± 0.039
0.0GlnPhe: 0.0 ± 0.0
6.196GlnGly: 6.196 ± 2.552
0.0GlnHis: 0.0 ± 0.0
4.957GlnIle: 4.957 ± 0.079
7.435GlnLys: 7.435 ± 3.416
4.957GlnLeu: 4.957 ± 1.846
1.239GlnMet: 1.239 ± 0.903
2.478GlnAsn: 2.478 ± 1.728
1.239GlnPro: 1.239 ± 0.903
3.717GlnGln: 3.717 ± 2.592
2.478GlnArg: 2.478 ± 0.039
2.478GlnSer: 2.478 ± 1.728
0.0GlnThr: 0.0 ± 0.0
1.239GlnVal: 1.239 ± 0.864
0.0GlnTrp: 0.0 ± 0.0
2.478GlnTyr: 2.478 ± 0.039
0.0GlnXaa: 0.0 ± 0.0
Arg
2.478ArgAla: 2.478 ± 0.039
0.0ArgCys: 0.0 ± 0.0
1.239ArgAsp: 1.239 ± 0.903
1.239ArgGlu: 1.239 ± 0.864
2.478ArgPhe: 2.478 ± 1.728
1.239ArgGly: 1.239 ± 0.864
1.239ArgHis: 1.239 ± 0.903
1.239ArgIle: 1.239 ± 0.903
2.478ArgLys: 2.478 ± 1.728
3.717ArgLeu: 3.717 ± 0.943
1.239ArgMet: 1.239 ± 0.903
1.239ArgAsn: 1.239 ± 0.864
2.478ArgPro: 2.478 ± 1.807
2.478ArgGln: 2.478 ± 0.039
0.0ArgArg: 0.0 ± 0.0
7.435ArgSer: 7.435 ± 0.118
4.957ArgThr: 4.957 ± 3.613
7.435ArgVal: 7.435 ± 0.118
1.239ArgTrp: 1.239 ± 0.903
4.957ArgTyr: 4.957 ± 3.613
0.0ArgXaa: 0.0 ± 0.0
Ser
8.674SerAla: 8.674 ± 0.746
0.0SerCys: 0.0 ± 0.0
8.674SerAsp: 8.674 ± 0.746
0.0SerGlu: 0.0 ± 0.0
2.478SerPhe: 2.478 ± 1.807
8.674SerGly: 8.674 ± 1.022
2.478SerHis: 2.478 ± 0.039
2.478SerIle: 2.478 ± 0.039
6.196SerLys: 6.196 ± 0.785
11.152SerLeu: 11.152 ± 0.706
0.0SerMet: 0.0 ± 0.624
4.957SerAsn: 4.957 ± 1.688
6.196SerPro: 6.196 ± 2.552
3.717SerGln: 3.717 ± 2.592
2.478SerArg: 2.478 ± 1.728
13.631SerSer: 13.631 ± 4.201
7.435SerThr: 7.435 ± 1.649
2.478SerVal: 2.478 ± 1.728
1.239SerTrp: 1.239 ± 0.864
1.239SerTyr: 1.239 ± 0.864
0.0SerXaa: 0.0 ± 0.0
Thr
2.478ThrAla: 2.478 ± 1.807
0.0ThrCys: 0.0 ± 0.0
2.478ThrAsp: 2.478 ± 0.039
2.478ThrGlu: 2.478 ± 1.807
1.239ThrPhe: 1.239 ± 0.864
1.239ThrGly: 1.239 ± 0.903
2.478ThrHis: 2.478 ± 1.807
1.239ThrIle: 1.239 ± 0.903
4.957ThrLys: 4.957 ± 0.079
1.239ThrLeu: 1.239 ± 0.864
0.0ThrMet: 0.0 ± 0.0
3.717ThrAsn: 3.717 ± 0.943
2.478ThrPro: 2.478 ± 1.807
0.0ThrGln: 0.0 ± 0.0
6.196ThrArg: 6.196 ± 0.982
3.717ThrSer: 3.717 ± 0.824
2.478ThrThr: 2.478 ± 0.039
6.196ThrVal: 6.196 ± 2.552
0.0ThrTrp: 0.0 ± 0.0
1.239ThrTyr: 1.239 ± 0.903
0.0ThrXaa: 0.0 ± 0.0
Val
1.239ValAla: 1.239 ± 0.864
0.0ValCys: 0.0 ± 0.0
6.196ValAsp: 6.196 ± 0.785
6.196ValGlu: 6.196 ± 2.749
3.717ValPhe: 3.717 ± 0.824
3.717ValGly: 3.717 ± 2.592
0.0ValHis: 0.0 ± 0.0
2.478ValIle: 2.478 ± 0.039
7.435ValLys: 7.435 ± 1.886
6.196ValLeu: 6.196 ± 0.785
0.0ValMet: 0.0 ± 0.0
2.478ValAsn: 2.478 ± 1.807
3.717ValPro: 3.717 ± 0.824
3.717ValGln: 3.717 ± 2.592
1.239ValArg: 1.239 ± 0.903
6.196ValSer: 6.196 ± 0.982
8.674ValThr: 8.674 ± 4.28
6.196ValVal: 6.196 ± 0.982
0.0ValTrp: 0.0 ± 0.0
2.478ValTyr: 2.478 ± 1.728
0.0ValXaa: 0.0 ± 0.0
Trp
2.478TrpAla: 2.478 ± 0.039
0.0TrpCys: 0.0 ± 0.0
1.239TrpAsp: 1.239 ± 0.903
1.239TrpGlu: 1.239 ± 0.903
0.0TrpPhe: 0.0 ± 0.0
0.0TrpGly: 0.0 ± 0.0
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
2.478TrpLys: 2.478 ± 1.807
0.0TrpLeu: 0.0 ± 0.0
1.239TrpMet: 1.239 ± 0.903
1.239TrpAsn: 1.239 ± 0.864
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
1.239TrpArg: 1.239 ± 0.903
2.478TrpSer: 2.478 ± 0.039
2.478TrpThr: 2.478 ± 1.807
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.239TyrAla: 1.239 ± 0.903
1.239TyrCys: 1.239 ± 0.903
2.478TyrAsp: 2.478 ± 1.728
1.239TyrGlu: 1.239 ± 0.903
3.717TyrPhe: 3.717 ± 0.943
1.239TyrGly: 1.239 ± 0.864
2.478TyrHis: 2.478 ± 0.039
2.478TyrIle: 2.478 ± 1.807
1.239TyrLys: 1.239 ± 0.864
3.717TyrLeu: 3.717 ± 0.943
1.239TyrMet: 1.239 ± 0.903
3.717TyrAsn: 3.717 ± 0.943
1.239TyrPro: 1.239 ± 0.903
0.0TyrGln: 0.0 ± 0.0
6.196TyrArg: 6.196 ± 2.749
2.478TyrSer: 2.478 ± 1.728
1.239TyrThr: 1.239 ± 0.903
2.478TyrVal: 2.478 ± 0.039
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (808 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski