Amino acid dipepetide frequency for Perch rhabdovirus (isolate Perch/France/PRV/1981)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.074AlaAla: 3.074 ± 0.845
0.838AlaCys: 0.838 ± 0.271
3.913AlaAsp: 3.913 ± 0.681
2.236AlaGlu: 2.236 ± 0.52
1.677AlaPhe: 1.677 ± 0.541
4.472AlaGly: 4.472 ± 0.581
0.559AlaHis: 0.559 ± 0.265
3.633AlaIle: 3.633 ± 0.705
3.633AlaLys: 3.633 ± 1.42
5.59AlaLeu: 5.59 ± 1.397
0.838AlaMet: 0.838 ± 0.56
0.838AlaAsn: 0.838 ± 0.308
3.074AlaPro: 3.074 ± 1.378
2.795AlaGln: 2.795 ± 0.69
4.751AlaArg: 4.751 ± 0.354
2.515AlaSer: 2.515 ± 0.837
3.354AlaThr: 3.354 ± 1.382
3.074AlaVal: 3.074 ± 2.001
1.118AlaTrp: 1.118 ± 0.392
1.956AlaTyr: 1.956 ± 0.703
0.0AlaXaa: 0.0 ± 0.0
Cys
1.118CysAla: 1.118 ± 0.864
0.0CysCys: 0.0 ± 0.0
0.838CysAsp: 0.838 ± 0.271
0.838CysGlu: 0.838 ± 0.427
0.559CysPhe: 0.559 ± 0.285
1.118CysGly: 1.118 ± 0.904
0.0CysHis: 0.0 ± 0.0
0.279CysIle: 0.279 ± 0.371
1.397CysLys: 1.397 ± 0.839
1.956CysLeu: 1.956 ± 0.464
0.0CysMet: 0.0 ± 0.0
0.559CysAsn: 0.559 ± 0.285
0.559CysPro: 0.559 ± 0.657
1.118CysGln: 1.118 ± 0.627
0.279CysArg: 0.279 ± 0.371
0.838CysSer: 0.838 ± 0.427
0.279CysThr: 0.279 ± 0.142
1.118CysVal: 1.118 ± 0.342
0.838CysTrp: 0.838 ± 0.308
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.795AspAla: 2.795 ± 0.883
0.838AspCys: 0.838 ± 0.369
2.236AspAsp: 2.236 ± 0.699
3.913AspGlu: 3.913 ± 0.749
2.515AspPhe: 2.515 ± 0.823
2.515AspGly: 2.515 ± 0.51
0.559AspHis: 0.559 ± 0.285
2.795AspIle: 2.795 ± 0.986
3.354AspLys: 3.354 ± 0.909
5.031AspLeu: 5.031 ± 0.672
2.515AspMet: 2.515 ± 0.753
3.074AspAsn: 3.074 ± 0.794
3.913AspPro: 3.913 ± 1.318
3.074AspGln: 3.074 ± 0.913
2.515AspArg: 2.515 ± 0.784
3.354AspSer: 3.354 ± 0.915
3.074AspThr: 3.074 ± 0.672
3.074AspVal: 3.074 ± 0.642
2.236AspTrp: 2.236 ± 0.978
3.074AspTyr: 3.074 ± 0.263
0.0AspXaa: 0.0 ± 0.0
Glu
4.751GluAla: 4.751 ± 1.891
0.559GluCys: 0.559 ± 0.657
3.354GluAsp: 3.354 ± 0.57
6.708GluGlu: 6.708 ± 1.787
4.472GluPhe: 4.472 ± 0.45
3.074GluGly: 3.074 ± 1.048
1.118GluHis: 1.118 ± 0.342
5.31GluIle: 5.31 ± 0.934
3.633GluLys: 3.633 ± 1.162
4.472GluLeu: 4.472 ± 0.235
2.236GluMet: 2.236 ± 0.645
3.074GluAsn: 3.074 ± 0.358
2.236GluPro: 2.236 ± 0.952
2.236GluGln: 2.236 ± 0.904
3.074GluArg: 3.074 ± 0.437
7.267GluSer: 7.267 ± 1.427
3.354GluThr: 3.354 ± 1.382
4.751GluVal: 4.751 ± 0.746
1.397GluTrp: 1.397 ± 0.516
1.956GluTyr: 1.956 ± 0.404
0.0GluXaa: 0.0 ± 0.0
Phe
1.118PheAla: 1.118 ± 0.452
1.118PheCys: 1.118 ± 0.53
2.236PheAsp: 2.236 ± 0.602
2.795PheGlu: 2.795 ± 0.595
1.956PhePhe: 1.956 ± 0.415
3.354PheGly: 3.354 ± 0.755
1.677PheHis: 1.677 ± 0.58
0.559PheIle: 0.559 ± 0.265
2.795PheLys: 2.795 ± 0.385
4.472PheLeu: 4.472 ± 1.543
1.118PheMet: 1.118 ± 0.508
1.397PheAsn: 1.397 ± 0.71
1.677PhePro: 1.677 ± 0.416
3.074PheGln: 3.074 ± 0.794
1.956PheArg: 1.956 ± 0.808
3.354PheSer: 3.354 ± 0.502
1.677PheThr: 1.677 ± 0.63
3.633PheVal: 3.633 ± 1.123
0.279PheTrp: 0.279 ± 0.142
0.838PheTyr: 0.838 ± 0.369
0.0PheXaa: 0.0 ± 0.0
Gly
3.074GlyAla: 3.074 ± 1.637
0.279GlyCys: 0.279 ± 0.371
5.31GlyAsp: 5.31 ± 1.128
3.354GlyGlu: 3.354 ± 0.534
3.074GlyPhe: 3.074 ± 0.931
4.192GlyGly: 4.192 ± 0.447
1.118GlyHis: 1.118 ± 0.452
4.751GlyIle: 4.751 ± 0.581
4.751GlyLys: 4.751 ± 1.116
6.987GlyLeu: 6.987 ± 1.441
1.397GlyMet: 1.397 ± 1.088
2.236GlyAsn: 2.236 ± 0.99
3.074GlyPro: 3.074 ± 2.096
1.677GlyGln: 1.677 ± 0.451
2.795GlyArg: 2.795 ± 0.629
5.031GlySer: 5.031 ± 0.229
3.633GlyThr: 3.633 ± 0.468
2.795GlyVal: 2.795 ± 1.403
1.956GlyTrp: 1.956 ± 0.516
1.677GlyTyr: 1.677 ± 0.737
0.0GlyXaa: 0.0 ± 0.0
His
0.838HisAla: 0.838 ± 0.427
0.279HisCys: 0.279 ± 0.371
1.118HisAsp: 1.118 ± 0.342
0.279HisGlu: 0.279 ± 0.142
1.956HisPhe: 1.956 ± 0.404
0.838HisGly: 0.838 ± 1.077
0.838HisHis: 0.838 ± 0.271
1.956HisIle: 1.956 ± 0.404
2.515HisLys: 2.515 ± 0.234
1.677HisLeu: 1.677 ± 0.417
0.279HisMet: 0.279 ± 0.142
0.279HisAsn: 0.279 ± 0.142
2.515HisPro: 2.515 ± 0.72
1.118HisGln: 1.118 ± 0.342
1.118HisArg: 1.118 ± 0.342
1.956HisSer: 1.956 ± 0.516
1.397HisThr: 1.397 ± 0.552
1.118HisVal: 1.118 ± 0.342
0.838HisTrp: 0.838 ± 0.271
1.397HisTyr: 1.397 ± 0.828
0.0HisXaa: 0.0 ± 0.0
Ile
3.354IleAla: 3.354 ± 0.612
0.559IleCys: 0.559 ± 0.657
3.913IleAsp: 3.913 ± 0.983
5.31IleGlu: 5.31 ± 0.178
2.795IlePhe: 2.795 ± 0.586
5.59IleGly: 5.59 ± 0.746
1.397IleHis: 1.397 ± 0.552
2.515IleIle: 2.515 ± 1.398
3.913IleLys: 3.913 ± 1.231
4.472IleLeu: 4.472 ± 0.805
1.118IleMet: 1.118 ± 0.387
1.677IleAsn: 1.677 ± 0.579
3.074IlePro: 3.074 ± 0.399
3.913IleGln: 3.913 ± 1.165
4.192IleArg: 4.192 ± 1.159
3.633IleSer: 3.633 ± 1.124
3.354IleThr: 3.354 ± 0.57
3.633IleVal: 3.633 ± 1.17
0.838IleTrp: 0.838 ± 0.369
2.515IleTyr: 2.515 ± 0.767
0.0IleXaa: 0.0 ± 0.0
Lys
3.074LysAla: 3.074 ± 0.849
0.559LysCys: 0.559 ± 0.31
2.795LysAsp: 2.795 ± 0.926
4.472LysGlu: 4.472 ± 0.798
1.956LysPhe: 1.956 ± 0.501
5.31LysGly: 5.31 ± 1.639
1.956LysHis: 1.956 ± 0.6
4.472LysIle: 4.472 ± 0.803
3.913LysLys: 3.913 ± 0.741
5.59LysLeu: 5.59 ± 1.705
2.515LysMet: 2.515 ± 0.393
3.633LysAsn: 3.633 ± 0.388
4.192LysPro: 4.192 ± 2.294
1.677LysGln: 1.677 ± 0.558
3.633LysArg: 3.633 ± 0.674
3.913LysSer: 3.913 ± 1.497
4.751LysThr: 4.751 ± 0.984
3.633LysVal: 3.633 ± 0.684
1.677LysTrp: 1.677 ± 0.446
1.956LysTyr: 1.956 ± 0.516
0.0LysXaa: 0.0 ± 0.0
Leu
6.708LeuAla: 6.708 ± 1.081
1.118LeuCys: 1.118 ± 0.278
6.987LeuAsp: 6.987 ± 1.739
6.149LeuGlu: 6.149 ± 0.595
2.236LeuPhe: 2.236 ± 0.545
7.267LeuGly: 7.267 ± 1.739
1.397LeuHis: 1.397 ± 0.56
8.105LeuIle: 8.105 ± 2.119
6.987LeuLys: 6.987 ± 1.398
7.267LeuLeu: 7.267 ± 1.31
2.515LeuMet: 2.515 ± 0.78
5.869LeuAsn: 5.869 ± 0.901
2.795LeuPro: 2.795 ± 0.51
2.515LeuGln: 2.515 ± 0.366
5.31LeuArg: 5.31 ± 0.751
7.267LeuSer: 7.267 ± 1.087
6.428LeuThr: 6.428 ± 1.027
5.031LeuVal: 5.031 ± 1.026
0.838LeuTrp: 0.838 ± 0.271
2.236LeuTyr: 2.236 ± 1.14
0.0LeuXaa: 0.0 ± 0.0
Met
1.677MetAla: 1.677 ± 0.427
0.559MetCys: 0.559 ± 0.265
2.236MetAsp: 2.236 ± 0.762
1.397MetGlu: 1.397 ± 0.395
1.397MetPhe: 1.397 ± 0.525
2.515MetGly: 2.515 ± 0.723
0.559MetHis: 0.559 ± 0.265
2.795MetIle: 2.795 ± 0.791
0.838MetLys: 0.838 ± 0.427
1.677MetLeu: 1.677 ± 0.73
2.515MetMet: 2.515 ± 0.972
1.118MetAsn: 1.118 ± 0.335
0.838MetPro: 0.838 ± 0.56
0.559MetGln: 0.559 ± 0.397
1.677MetArg: 1.677 ± 0.451
3.354MetSer: 3.354 ± 0.478
1.397MetThr: 1.397 ± 0.897
0.559MetVal: 0.559 ± 0.397
0.279MetTrp: 0.279 ± 0.328
0.279MetTyr: 0.279 ± 0.142
0.0MetXaa: 0.0 ± 0.0
Asn
2.515AsnAla: 2.515 ± 1.173
1.118AsnCys: 1.118 ± 0.342
2.236AsnAsp: 2.236 ± 0.291
2.236AsnGlu: 2.236 ± 0.609
1.677AsnPhe: 1.677 ± 0.609
3.074AsnGly: 3.074 ± 1.043
1.397AsnHis: 1.397 ± 0.463
3.354AsnIle: 3.354 ± 0.763
2.515AsnLys: 2.515 ± 0.924
4.751AsnLeu: 4.751 ± 0.552
0.838AsnMet: 0.838 ± 0.369
3.074AsnAsn: 3.074 ± 0.727
1.956AsnPro: 1.956 ± 0.415
2.515AsnGln: 2.515 ± 0.422
1.118AsnArg: 1.118 ± 0.57
4.192AsnSer: 4.192 ± 0.971
2.236AsnThr: 2.236 ± 0.862
1.956AsnVal: 1.956 ± 0.745
1.677AsnTrp: 1.677 ± 0.68
1.397AsnTyr: 1.397 ± 0.601
0.0AsnXaa: 0.0 ± 0.0
Pro
2.515ProAla: 2.515 ± 0.767
0.559ProCys: 0.559 ± 0.329
1.397ProAsp: 1.397 ± 0.395
4.751ProGlu: 4.751 ± 1.185
2.236ProPhe: 2.236 ± 0.883
1.677ProGly: 1.677 ± 1.508
2.236ProHis: 2.236 ± 0.781
2.515ProIle: 2.515 ± 0.767
3.913ProLys: 3.913 ± 2.619
4.751ProLeu: 4.751 ± 0.354
0.838ProMet: 0.838 ± 0.541
1.118ProAsn: 1.118 ± 0.457
1.956ProPro: 1.956 ± 0.653
0.838ProGln: 0.838 ± 0.429
0.279ProArg: 0.279 ± 0.142
5.031ProSer: 5.031 ± 1.423
4.751ProThr: 4.751 ± 0.256
4.472ProVal: 4.472 ± 1.416
0.559ProTrp: 0.559 ± 0.31
1.677ProTyr: 1.677 ± 1.116
0.0ProXaa: 0.0 ± 0.0
Gln
2.236GlnAla: 2.236 ± 1.155
0.279GlnCys: 0.279 ± 0.142
2.795GlnAsp: 2.795 ± 1.211
3.354GlnGlu: 3.354 ± 1.127
2.236GlnPhe: 2.236 ± 0.329
2.236GlnGly: 2.236 ± 0.555
0.559GlnHis: 0.559 ± 0.285
1.118GlnIle: 1.118 ± 0.366
2.236GlnLys: 2.236 ± 0.647
2.236GlnLeu: 2.236 ± 0.632
1.118GlnMet: 1.118 ± 0.986
2.795GlnAsn: 2.795 ± 1.728
2.515GlnPro: 2.515 ± 0.516
1.118GlnGln: 1.118 ± 0.57
1.956GlnArg: 1.956 ± 0.383
3.913GlnSer: 3.913 ± 0.927
1.397GlnThr: 1.397 ± 0.601
1.397GlnVal: 1.397 ± 0.463
0.279GlnTrp: 0.279 ± 0.348
1.118GlnTyr: 1.118 ± 0.57
0.0GlnXaa: 0.0 ± 0.0
Arg
2.515ArgAla: 2.515 ± 0.502
1.397ArgCys: 1.397 ± 0.448
2.515ArgAsp: 2.515 ± 0.971
4.751ArgGlu: 4.751 ± 1.302
1.956ArgPhe: 1.956 ± 0.701
3.074ArgGly: 3.074 ± 0.819
1.677ArgHis: 1.677 ± 0.451
1.677ArgIle: 1.677 ± 0.739
3.633ArgLys: 3.633 ± 0.639
5.031ArgLeu: 5.031 ± 0.672
2.515ArgMet: 2.515 ± 0.767
3.074ArgAsn: 3.074 ± 0.646
1.956ArgPro: 1.956 ± 0.366
2.236ArgGln: 2.236 ± 0.394
2.515ArgArg: 2.515 ± 0.599
4.751ArgSer: 4.751 ± 1.052
1.956ArgThr: 1.956 ± 0.6
3.074ArgVal: 3.074 ± 1.024
0.838ArgTrp: 0.838 ± 0.271
1.118ArgTyr: 1.118 ± 0.479
0.0ArgXaa: 0.0 ± 0.0
Ser
4.751SerAla: 4.751 ± 0.668
1.118SerCys: 1.118 ± 0.57
6.428SerAsp: 6.428 ± 0.827
5.031SerGlu: 5.031 ± 0.307
1.956SerPhe: 1.956 ± 0.533
3.074SerGly: 3.074 ± 0.652
3.913SerHis: 3.913 ± 1.317
5.031SerIle: 5.031 ± 1.296
5.869SerLys: 5.869 ± 0.587
8.944SerLeu: 8.944 ± 1.229
1.956SerMet: 1.956 ± 0.775
2.515SerAsn: 2.515 ± 0.865
2.515SerPro: 2.515 ± 0.422
2.515SerGln: 2.515 ± 0.866
2.795SerArg: 2.795 ± 0.765
5.59SerSer: 5.59 ± 0.441
4.472SerThr: 4.472 ± 0.467
6.428SerVal: 6.428 ± 2.215
1.956SerTrp: 1.956 ± 0.7
2.236SerTyr: 2.236 ± 0.609
0.0SerXaa: 0.0 ± 0.0
Thr
2.515ThrAla: 2.515 ± 0.599
1.677ThrCys: 1.677 ± 0.442
2.236ThrAsp: 2.236 ± 0.775
3.633ThrGlu: 3.633 ± 0.468
1.677ThrPhe: 1.677 ± 0.427
3.633ThrGly: 3.633 ± 0.674
0.838ThrHis: 0.838 ± 0.271
3.633ThrIle: 3.633 ± 0.639
4.192ThrLys: 4.192 ± 0.765
7.826ThrLeu: 7.826 ± 0.804
0.838ThrMet: 0.838 ± 0.368
2.795ThrAsn: 2.795 ± 0.758
3.074ThrPro: 3.074 ± 0.919
0.559ThrGln: 0.559 ± 0.265
3.913ThrArg: 3.913 ± 0.481
3.913ThrSer: 3.913 ± 0.551
4.192ThrThr: 4.192 ± 0.562
3.913ThrVal: 3.913 ± 0.731
1.118ThrTrp: 1.118 ± 0.57
1.118ThrTyr: 1.118 ± 0.452
0.0ThrXaa: 0.0 ± 0.0
Val
3.354ValAla: 3.354 ± 1.455
0.559ValCys: 0.559 ± 0.285
1.677ValAsp: 1.677 ± 1.299
4.472ValGlu: 4.472 ± 1.141
2.515ValPhe: 2.515 ± 1.268
3.074ValGly: 3.074 ± 1.202
0.838ValHis: 0.838 ± 1.087
4.751ValIle: 4.751 ± 1.153
2.795ValLys: 2.795 ± 1.13
6.149ValLeu: 6.149 ± 1.041
1.677ValMet: 1.677 ± 0.582
3.354ValAsn: 3.354 ± 0.653
3.633ValPro: 3.633 ± 0.297
1.956ValGln: 1.956 ± 1.038
4.192ValArg: 4.192 ± 1.148
4.192ValSer: 4.192 ± 0.603
4.472ValThr: 4.472 ± 0.45
3.074ValVal: 3.074 ± 1.628
0.559ValTrp: 0.559 ± 0.397
1.397ValTyr: 1.397 ± 0.415
0.0ValXaa: 0.0 ± 0.0
Trp
0.838TrpAla: 0.838 ± 0.369
0.0TrpCys: 0.0 ± 0.0
1.956TrpAsp: 1.956 ± 0.624
1.677TrpGlu: 1.677 ± 0.285
0.838TrpPhe: 0.838 ± 0.271
1.118TrpGly: 1.118 ± 0.342
0.559TrpHis: 0.559 ± 0.397
0.838TrpIle: 0.838 ± 0.271
1.397TrpLys: 1.397 ± 0.56
1.397TrpLeu: 1.397 ± 0.243
0.279TrpMet: 0.279 ± 0.142
1.956TrpAsn: 1.956 ± 0.631
0.559TrpPro: 0.559 ± 0.285
0.0TrpGln: 0.0 ± 0.0
1.397TrpArg: 1.397 ± 0.351
2.515TrpSer: 2.515 ± 0.971
0.838TrpThr: 0.838 ± 0.749
1.118TrpVal: 1.118 ± 0.457
0.279TrpTrp: 0.279 ± 0.142
0.559TrpTyr: 0.559 ± 0.265
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.118TyrAla: 1.118 ± 0.57
0.279TyrCys: 0.279 ± 0.328
0.279TyrAsp: 0.279 ± 0.142
1.677TyrGlu: 1.677 ± 0.427
1.677TyrPhe: 1.677 ± 0.579
1.956TyrGly: 1.956 ± 0.516
1.118TyrHis: 1.118 ± 0.604
1.677TyrIle: 1.677 ± 0.256
1.397TyrLys: 1.397 ± 0.463
4.751TyrLeu: 4.751 ± 0.746
0.838TyrMet: 0.838 ± 0.56
1.397TyrAsn: 1.397 ± 0.461
1.956TyrPro: 1.956 ± 0.704
1.397TyrGln: 1.397 ± 0.395
2.795TyrArg: 2.795 ± 0.564
2.515TyrSer: 2.515 ± 0.587
0.279TyrThr: 0.279 ± 0.469
0.838TyrVal: 0.838 ± 0.308
0.559TyrTrp: 0.559 ± 0.285
0.838TyrTyr: 0.838 ± 0.56
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3579 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski