Amino acid dipepetide frequency for Giant house spider associated circular virus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.53AlaAla: 7.53 ± 2.702
0.0AlaCys: 0.0 ± 0.0
1.506AlaAsp: 1.506 ± 0.823
1.506AlaGlu: 1.506 ± 0.823
4.518AlaPhe: 4.518 ± 0.197
4.518AlaGly: 4.518 ± 2.075
3.012AlaHis: 3.012 ± 0.626
3.012AlaIle: 3.012 ± 2.898
0.0AlaLys: 0.0 ± 0.0
7.53AlaLeu: 7.53 ± 4.974
1.506AlaMet: 1.506 ± 1.449
1.506AlaAsn: 1.506 ± 0.823
6.024AlaPro: 6.024 ± 1.02
3.012AlaGln: 3.012 ± 0.626
6.024AlaArg: 6.024 ± 1.252
9.036AlaSer: 9.036 ± 0.394
7.53AlaThr: 7.53 ± 0.429
1.506AlaVal: 1.506 ± 0.823
1.506AlaTrp: 1.506 ± 0.823
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
1.506CysGly: 1.506 ± 0.823
0.0CysHis: 0.0 ± 0.0
1.506CysIle: 1.506 ± 0.823
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
1.506CysMet: 1.506 ± 0.823
1.506CysAsn: 1.506 ± 0.823
1.506CysPro: 1.506 ± 0.823
0.0CysGln: 0.0 ± 0.0
1.506CysArg: 1.506 ± 1.449
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.506CysTyr: 1.506 ± 0.823
0.0CysXaa: 0.0 ± 0.0
Asp
4.518AspAla: 4.518 ± 0.197
0.0AspCys: 0.0 ± 0.0
1.506AspAsp: 1.506 ± 1.449
6.024AspGlu: 6.024 ± 3.292
1.506AspPhe: 1.506 ± 0.823
3.012AspGly: 3.012 ± 0.626
1.506AspHis: 1.506 ± 0.823
1.506AspIle: 1.506 ± 0.823
0.0AspLys: 0.0 ± 0.0
4.518AspLeu: 4.518 ± 0.197
1.506AspMet: 1.506 ± 1.449
9.036AspAsn: 9.036 ± 4.151
0.0AspPro: 0.0 ± 0.0
1.506AspGln: 1.506 ± 1.449
1.506AspArg: 1.506 ± 0.823
4.518AspSer: 4.518 ± 2.075
4.518AspThr: 4.518 ± 2.075
4.518AspVal: 4.518 ± 2.469
1.506AspTrp: 1.506 ± 0.823
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
3.012GluAla: 3.012 ± 1.646
1.506GluCys: 1.506 ± 0.823
6.024GluAsp: 6.024 ± 3.292
1.506GluGlu: 1.506 ± 0.823
1.506GluPhe: 1.506 ± 0.823
3.012GluGly: 3.012 ± 1.646
1.506GluHis: 1.506 ± 0.823
1.506GluIle: 1.506 ± 0.823
0.0GluLys: 0.0 ± 0.0
3.012GluLeu: 3.012 ± 0.626
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
4.518GluPro: 4.518 ± 2.469
1.506GluGln: 1.506 ± 0.823
3.012GluArg: 3.012 ± 1.646
1.506GluSer: 1.506 ± 0.823
4.518GluThr: 4.518 ± 2.469
1.506GluVal: 1.506 ± 0.823
0.0GluTrp: 0.0 ± 0.0
1.506GluTyr: 1.506 ± 0.823
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.0PheCys: 0.0 ± 0.0
6.024PheAsp: 6.024 ± 3.292
0.0PheGlu: 0.0 ± 0.0
0.0PhePhe: 0.0 ± 0.0
1.506PheGly: 1.506 ± 0.823
0.0PheHis: 0.0 ± 0.0
1.506PheIle: 1.506 ± 1.449
3.012PheLys: 3.012 ± 1.646
7.53PheLeu: 7.53 ± 4.115
0.0PheMet: 0.0 ± 0.0
1.506PheAsn: 1.506 ± 0.823
3.012PhePro: 3.012 ± 2.898
0.0PheGln: 0.0 ± 0.0
3.012PheArg: 3.012 ± 1.646
0.0PheSer: 0.0 ± 0.0
3.012PheThr: 3.012 ± 2.898
4.518PheVal: 4.518 ± 0.197
0.0PheTrp: 0.0 ± 0.0
1.506PheTyr: 1.506 ± 0.823
0.0PheXaa: 0.0 ± 0.0
Gly
9.036GlyAla: 9.036 ± 4.151
0.0GlyCys: 0.0 ± 0.0
4.518GlyAsp: 4.518 ± 2.075
1.506GlyGlu: 1.506 ± 0.823
0.0GlyPhe: 0.0 ± 0.0
6.024GlyGly: 6.024 ± 3.525
1.506GlyHis: 1.506 ± 0.823
3.012GlyIle: 3.012 ± 1.646
1.506GlyLys: 1.506 ± 0.823
3.012GlyLeu: 3.012 ± 0.626
0.0GlyMet: 0.0 ± 0.0
1.506GlyAsn: 1.506 ± 0.823
6.024GlyPro: 6.024 ± 1.02
10.542GlyGln: 10.542 ± 1.216
6.024GlyArg: 6.024 ± 3.525
4.518GlySer: 4.518 ± 4.348
6.024GlyThr: 6.024 ± 1.252
3.012GlyVal: 3.012 ± 0.626
0.0GlyTrp: 0.0 ± 0.0
0.0GlyTyr: 0.0 ± 0.0
0.0GlyXaa: 0.0 ± 0.0
His
0.0HisAla: 0.0 ± 0.0
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
1.506HisPhe: 1.506 ± 0.823
1.506HisGly: 1.506 ± 0.823
0.0HisHis: 0.0 ± 0.0
4.518HisIle: 4.518 ± 0.197
3.012HisLys: 3.012 ± 0.626
6.024HisLeu: 6.024 ± 3.292
1.506HisMet: 1.506 ± 0.682
0.0HisAsn: 0.0 ± 0.0
1.506HisPro: 1.506 ± 0.823
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
1.506HisThr: 1.506 ± 0.823
1.506HisVal: 1.506 ± 0.823
1.506HisTrp: 1.506 ± 0.823
1.506HisTyr: 1.506 ± 0.823
0.0HisXaa: 0.0 ± 0.0
Ile
4.518IleAla: 4.518 ± 2.075
0.0IleCys: 0.0 ± 0.0
1.506IleAsp: 1.506 ± 1.449
0.0IleGlu: 0.0 ± 0.0
1.506IlePhe: 1.506 ± 0.823
9.036IleGly: 9.036 ± 1.879
0.0IleHis: 0.0 ± 0.0
0.0IleIle: 0.0 ± 0.0
1.506IleLys: 1.506 ± 0.823
4.518IleLeu: 4.518 ± 0.197
0.0IleMet: 0.0 ± 0.0
3.012IleAsn: 3.012 ± 1.646
1.506IlePro: 1.506 ± 0.823
7.53IleGln: 7.53 ± 0.429
3.012IleArg: 3.012 ± 1.646
4.518IleSer: 4.518 ± 2.075
1.506IleThr: 1.506 ± 0.823
3.012IleVal: 3.012 ± 0.626
0.0IleTrp: 0.0 ± 0.0
1.506IleTyr: 1.506 ± 0.823
0.0IleXaa: 0.0 ± 0.0
Lys
1.506LysAla: 1.506 ± 0.823
0.0LysCys: 0.0 ± 0.0
4.518LysAsp: 4.518 ± 0.197
1.506LysGlu: 1.506 ± 0.823
1.506LysPhe: 1.506 ± 0.823
4.518LysGly: 4.518 ± 0.197
0.0LysHis: 0.0 ± 0.0
1.506LysIle: 1.506 ± 1.449
4.518LysLys: 4.518 ± 0.197
3.012LysLeu: 3.012 ± 0.626
1.506LysMet: 1.506 ± 1.449
0.0LysAsn: 0.0 ± 0.0
0.0LysPro: 0.0 ± 0.0
3.012LysGln: 3.012 ± 1.646
4.518LysArg: 4.518 ± 0.197
6.024LysSer: 6.024 ± 1.02
3.012LysThr: 3.012 ± 1.646
3.012LysVal: 3.012 ± 0.626
3.012LysTrp: 3.012 ± 1.646
3.012LysTyr: 3.012 ± 2.898
0.0LysXaa: 0.0 ± 0.0
Leu
6.024LeuAla: 6.024 ± 1.252
1.506LeuCys: 1.506 ± 1.449
1.506LeuAsp: 1.506 ± 0.823
4.518LeuGlu: 4.518 ± 2.469
1.506LeuPhe: 1.506 ± 0.823
6.024LeuGly: 6.024 ± 1.252
3.012LeuHis: 3.012 ± 1.646
7.53LeuIle: 7.53 ± 0.429
10.542LeuLys: 10.542 ± 1.056
13.554LeuLeu: 13.554 ± 2.862
1.506LeuMet: 1.506 ± 0.823
3.012LeuAsn: 3.012 ± 1.646
9.036LeuPro: 9.036 ± 4.938
1.506LeuGln: 1.506 ± 1.449
9.036LeuArg: 9.036 ± 4.938
6.024LeuSer: 6.024 ± 1.252
9.036LeuThr: 9.036 ± 0.394
0.0LeuVal: 0.0 ± 0.0
4.518LeuTrp: 4.518 ± 2.075
3.012LeuTyr: 3.012 ± 0.626
0.0LeuXaa: 0.0 ± 0.0
Met
0.0MetAla: 0.0 ± 0.0
1.506MetCys: 1.506 ± 0.823
0.0MetAsp: 0.0 ± 0.0
1.506MetGlu: 1.506 ± 0.823
0.0MetPhe: 0.0 ± 0.0
0.0MetGly: 0.0 ± 0.0
1.506MetHis: 1.506 ± 0.823
1.506MetIle: 1.506 ± 1.449
0.0MetLys: 0.0 ± 0.0
3.012MetLeu: 3.012 ± 0.626
0.0MetMet: 0.0 ± 0.0
1.506MetAsn: 1.506 ± 1.449
4.518MetPro: 4.518 ± 2.075
1.506MetGln: 1.506 ± 0.823
1.506MetArg: 1.506 ± 1.449
1.506MetSer: 1.506 ± 0.823
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
9.036AsnAla: 9.036 ± 0.394
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
3.012AsnGlu: 3.012 ± 1.646
1.506AsnPhe: 1.506 ± 0.823
1.506AsnGly: 1.506 ± 0.823
0.0AsnHis: 0.0 ± 0.0
3.012AsnIle: 3.012 ± 1.646
0.0AsnLys: 0.0 ± 0.0
6.024AsnLeu: 6.024 ± 1.02
1.506AsnMet: 1.506 ± 0.551
3.012AsnAsn: 3.012 ± 0.626
4.518AsnPro: 4.518 ± 0.197
3.012AsnGln: 3.012 ± 0.626
1.506AsnArg: 1.506 ± 1.449
3.012AsnSer: 3.012 ± 0.626
4.518AsnThr: 4.518 ± 2.075
1.506AsnVal: 1.506 ± 0.823
0.0AsnTrp: 0.0 ± 0.0
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
3.012ProAla: 3.012 ± 1.646
0.0ProCys: 0.0 ± 0.0
0.0ProAsp: 0.0 ± 0.0
4.518ProGlu: 4.518 ± 2.469
1.506ProPhe: 1.506 ± 0.823
1.506ProGly: 1.506 ± 1.449
3.012ProHis: 3.012 ± 1.646
1.506ProIle: 1.506 ± 0.823
3.012ProLys: 3.012 ± 0.626
10.542ProLeu: 10.542 ± 1.216
0.0ProMet: 0.0 ± 0.0
6.024ProAsn: 6.024 ± 1.02
6.024ProPro: 6.024 ± 3.292
3.012ProGln: 3.012 ± 1.646
3.012ProArg: 3.012 ± 0.626
1.506ProSer: 1.506 ± 0.823
4.518ProThr: 4.518 ± 0.197
9.036ProVal: 9.036 ± 0.394
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
6.024GlnAla: 6.024 ± 1.252
1.506GlnCys: 1.506 ± 0.823
1.506GlnAsp: 1.506 ± 0.823
7.53GlnGlu: 7.53 ± 1.843
3.012GlnPhe: 3.012 ± 0.626
4.518GlnGly: 4.518 ± 2.075
1.506GlnHis: 1.506 ± 0.823
1.506GlnIle: 1.506 ± 1.449
1.506GlnLys: 1.506 ± 0.823
3.012GlnLeu: 3.012 ± 0.626
0.0GlnMet: 0.0 ± 0.0
1.506GlnAsn: 1.506 ± 0.823
0.0GlnPro: 0.0 ± 0.0
3.012GlnGln: 3.012 ± 0.626
1.506GlnArg: 1.506 ± 1.449
1.506GlnSer: 1.506 ± 1.449
4.518GlnThr: 4.518 ± 2.469
4.518GlnVal: 4.518 ± 4.348
3.012GlnTrp: 3.012 ± 1.646
1.506GlnTyr: 1.506 ± 1.449
0.0GlnXaa: 0.0 ± 0.0
Arg
4.518ArgAla: 4.518 ± 0.197
0.0ArgCys: 0.0 ± 0.0
6.024ArgAsp: 6.024 ± 1.02
0.0ArgGlu: 0.0 ± 0.0
4.518ArgPhe: 4.518 ± 2.075
3.012ArgGly: 3.012 ± 1.646
1.506ArgHis: 1.506 ± 0.823
0.0ArgIle: 0.0 ± 0.0
3.012ArgLys: 3.012 ± 0.626
3.012ArgLeu: 3.012 ± 0.626
0.0ArgMet: 0.0 ± 0.0
4.518ArgAsn: 4.518 ± 0.197
0.0ArgPro: 0.0 ± 0.0
6.024ArgGln: 6.024 ± 1.252
9.036ArgArg: 9.036 ± 1.879
7.53ArgSer: 7.53 ± 2.702
3.012ArgThr: 3.012 ± 1.646
4.518ArgVal: 4.518 ± 4.348
0.0ArgTrp: 0.0 ± 0.0
4.518ArgTyr: 4.518 ± 0.197
0.0ArgXaa: 0.0 ± 0.0
Ser
3.012SerAla: 3.012 ± 2.898
0.0SerCys: 0.0 ± 0.0
1.506SerAsp: 1.506 ± 0.823
0.0SerGlu: 0.0 ± 0.0
1.506SerPhe: 1.506 ± 0.823
6.024SerGly: 6.024 ± 3.525
1.506SerHis: 1.506 ± 1.449
9.036SerIle: 9.036 ± 1.879
4.518SerLys: 4.518 ± 0.197
4.518SerLeu: 4.518 ± 2.469
3.012SerMet: 3.012 ± 0.626
4.518SerAsn: 4.518 ± 2.075
1.506SerPro: 1.506 ± 1.449
1.506SerGln: 1.506 ± 1.449
1.506SerArg: 1.506 ± 1.449
3.012SerSer: 3.012 ± 1.646
7.53SerThr: 7.53 ± 0.429
6.024SerVal: 6.024 ± 1.252
0.0SerTrp: 0.0 ± 0.0
1.506SerTyr: 1.506 ± 1.449
0.0SerXaa: 0.0 ± 0.0
Thr
7.53ThrAla: 7.53 ± 2.702
4.518ThrCys: 4.518 ± 2.469
3.012ThrAsp: 3.012 ± 2.898
3.012ThrGlu: 3.012 ± 1.646
3.012ThrPhe: 3.012 ± 1.646
4.518ThrGly: 4.518 ± 2.075
3.012ThrHis: 3.012 ± 1.646
1.506ThrIle: 1.506 ± 0.823
4.518ThrLys: 4.518 ± 2.469
6.024ThrLeu: 6.024 ± 1.252
1.506ThrMet: 1.506 ± 0.823
1.506ThrAsn: 1.506 ± 0.823
6.024ThrPro: 6.024 ± 1.02
3.012ThrGln: 3.012 ± 2.898
1.506ThrArg: 1.506 ± 0.823
4.518ThrSer: 4.518 ± 4.348
6.024ThrThr: 6.024 ± 3.525
6.024ThrVal: 6.024 ± 1.252
3.012ThrTrp: 3.012 ± 1.646
4.518ThrTyr: 4.518 ± 0.197
0.0ThrXaa: 0.0 ± 0.0
Val
1.506ValAla: 1.506 ± 0.823
0.0ValCys: 0.0 ± 0.0
4.518ValAsp: 4.518 ± 2.075
1.506ValGlu: 1.506 ± 0.823
4.518ValPhe: 4.518 ± 0.197
3.012ValGly: 3.012 ± 0.626
0.0ValHis: 0.0 ± 0.0
1.506ValIle: 1.506 ± 0.823
7.53ValLys: 7.53 ± 2.702
7.53ValLeu: 7.53 ± 1.843
3.012ValMet: 3.012 ± 0.626
3.012ValAsn: 3.012 ± 0.626
1.506ValPro: 1.506 ± 0.823
3.012ValGln: 3.012 ± 0.626
3.012ValArg: 3.012 ± 2.898
1.506ValSer: 1.506 ± 0.823
7.53ValThr: 7.53 ± 2.702
0.0ValVal: 0.0 ± 0.0
3.012ValTrp: 3.012 ± 0.626
1.506ValTyr: 1.506 ± 0.823
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
4.518TrpAsp: 4.518 ± 2.075
1.506TrpGlu: 1.506 ± 0.823
1.506TrpPhe: 1.506 ± 1.449
0.0TrpGly: 0.0 ± 0.0
1.506TrpHis: 1.506 ± 0.823
0.0TrpIle: 0.0 ± 0.0
1.506TrpLys: 1.506 ± 0.823
3.012TrpLeu: 3.012 ± 1.646
0.0TrpMet: 0.0 ± 0.0
1.506TrpAsn: 1.506 ± 0.823
1.506TrpPro: 1.506 ± 0.823
0.0TrpGln: 0.0 ± 0.0
1.506TrpArg: 1.506 ± 0.823
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
1.506TrpVal: 1.506 ± 0.823
0.0TrpTrp: 0.0 ± 0.0
1.506TrpTyr: 1.506 ± 0.823
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
4.518TyrAsp: 4.518 ± 2.075
1.506TyrGlu: 1.506 ± 0.823
1.506TyrPhe: 1.506 ± 0.823
3.012TyrGly: 3.012 ± 0.626
1.506TyrHis: 1.506 ± 0.823
3.012TyrIle: 3.012 ± 1.646
0.0TyrLys: 0.0 ± 0.0
3.012TyrLeu: 3.012 ± 1.646
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
3.012TyrPro: 3.012 ± 1.646
0.0TyrGln: 0.0 ± 0.0
3.012TyrArg: 3.012 ± 2.898
1.506TyrSer: 1.506 ± 1.449
0.0TyrThr: 0.0 ± 0.0
3.012TyrVal: 3.012 ± 0.626
0.0TyrTrp: 0.0 ± 0.0
1.506TyrTyr: 1.506 ± 1.449
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (665 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski