Amino acid dipepetide frequency for Xanthomonas virus Xp10

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
15.107AlaAla: 15.107 ± 2.222
1.271AlaCys: 1.271 ± 0.379
5.908AlaAsp: 5.908 ± 0.74
6.881AlaGlu: 6.881 ± 0.729
2.692AlaPhe: 2.692 ± 0.435
9.423AlaGly: 9.423 ± 0.884
1.346AlaHis: 1.346 ± 0.35
6.357AlaIle: 6.357 ± 0.765
5.983AlaLys: 5.983 ± 0.717
8.376AlaLeu: 8.376 ± 0.999
2.244AlaMet: 2.244 ± 0.517
4.338AlaAsn: 4.338 ± 0.718
3.59AlaPro: 3.59 ± 0.48
6.058AlaGln: 6.058 ± 0.779
6.058AlaArg: 6.058 ± 0.721
6.955AlaSer: 6.955 ± 0.84
5.31AlaThr: 5.31 ± 0.94
6.133AlaVal: 6.133 ± 0.678
2.468AlaTrp: 2.468 ± 0.368
3.964AlaTyr: 3.964 ± 0.505
0.0AlaXaa: 0.0 ± 0.0
Cys
1.047CysAla: 1.047 ± 0.31
0.224CysCys: 0.224 ± 0.113
0.449CysAsp: 0.449 ± 0.243
0.598CysGlu: 0.598 ± 0.238
0.15CysPhe: 0.15 ± 0.088
0.748CysGly: 0.748 ± 0.249
0.524CysHis: 0.524 ± 0.232
0.299CysIle: 0.299 ± 0.145
0.449CysLys: 0.449 ± 0.18
0.748CysLeu: 0.748 ± 0.207
0.224CysMet: 0.224 ± 0.118
0.374CysAsn: 0.374 ± 0.161
0.224CysPro: 0.224 ± 0.13
0.449CysGln: 0.449 ± 0.141
0.449CysArg: 0.449 ± 0.19
0.598CysSer: 0.598 ± 0.231
0.823CysThr: 0.823 ± 0.3
0.598CysVal: 0.598 ± 0.257
0.374CysTrp: 0.374 ± 0.158
0.524CysTyr: 0.524 ± 0.255
0.0CysXaa: 0.0 ± 0.0
Asp
5.31AspAla: 5.31 ± 0.694
0.374AspCys: 0.374 ± 0.231
3.365AspAsp: 3.365 ± 0.513
2.618AspGlu: 2.618 ± 0.358
2.169AspPhe: 2.169 ± 0.407
5.31AspGly: 5.31 ± 0.813
1.047AspHis: 1.047 ± 0.278
2.917AspIle: 2.917 ± 0.343
2.468AspLys: 2.468 ± 0.437
5.16AspLeu: 5.16 ± 0.741
1.87AspMet: 1.87 ± 0.33
2.318AspAsn: 2.318 ± 0.56
2.468AspPro: 2.468 ± 0.471
3.365AspGln: 3.365 ± 0.447
3.066AspArg: 3.066 ± 0.61
3.216AspSer: 3.216 ± 0.472
4.039AspThr: 4.039 ± 0.66
3.665AspVal: 3.665 ± 0.57
1.122AspTrp: 1.122 ± 0.283
1.645AspTyr: 1.645 ± 0.319
0.0AspXaa: 0.0 ± 0.0
Glu
6.507GluAla: 6.507 ± 1.166
1.047GluCys: 1.047 ± 0.301
3.066GluAsp: 3.066 ± 0.587
3.365GluGlu: 3.365 ± 0.59
1.496GluPhe: 1.496 ± 0.49
3.066GluGly: 3.066 ± 0.497
0.972GluHis: 0.972 ± 0.247
2.992GluIle: 2.992 ± 0.456
2.244GluLys: 2.244 ± 0.457
5.759GluLeu: 5.759 ± 0.644
1.271GluMet: 1.271 ± 0.275
1.72GluAsn: 1.72 ± 0.417
1.271GluPro: 1.271 ± 0.361
2.468GluGln: 2.468 ± 0.393
3.291GluArg: 3.291 ± 0.625
3.216GluSer: 3.216 ± 0.534
3.066GluThr: 3.066 ± 0.387
4.039GluVal: 4.039 ± 0.463
0.748GluTrp: 0.748 ± 0.286
1.795GluTyr: 1.795 ± 0.471
0.0GluXaa: 0.0 ± 0.0
Phe
3.066PheAla: 3.066 ± 0.537
0.299PheCys: 0.299 ± 0.124
3.066PheAsp: 3.066 ± 0.466
1.571PheGlu: 1.571 ± 0.306
0.673PhePhe: 0.673 ± 0.232
2.244PheGly: 2.244 ± 0.371
0.748PheHis: 0.748 ± 0.209
1.421PheIle: 1.421 ± 0.234
1.047PheLys: 1.047 ± 0.303
2.244PheLeu: 2.244 ± 0.38
0.598PheMet: 0.598 ± 0.237
0.823PheAsn: 0.823 ± 0.212
1.047PhePro: 1.047 ± 0.236
1.047PheGln: 1.047 ± 0.25
1.122PheArg: 1.122 ± 0.304
1.945PheSer: 1.945 ± 0.368
1.795PheThr: 1.795 ± 0.338
2.393PheVal: 2.393 ± 0.517
0.823PheTrp: 0.823 ± 0.206
0.673PheTyr: 0.673 ± 0.28
0.0PheXaa: 0.0 ± 0.0
Gly
6.432GlyAla: 6.432 ± 0.902
0.748GlyCys: 0.748 ± 0.235
4.263GlyAsp: 4.263 ± 0.527
4.487GlyGlu: 4.487 ± 0.587
2.244GlyPhe: 2.244 ± 0.441
5.684GlyGly: 5.684 ± 0.598
1.271GlyHis: 1.271 ± 0.319
3.44GlyIle: 3.44 ± 0.536
4.936GlyLys: 4.936 ± 0.551
7.255GlyLeu: 7.255 ± 0.949
2.318GlyMet: 2.318 ± 0.382
3.066GlyAsn: 3.066 ± 0.465
1.945GlyPro: 1.945 ± 0.339
3.889GlyGln: 3.889 ± 0.53
4.712GlyArg: 4.712 ± 0.536
6.656GlySer: 6.656 ± 0.602
5.534GlyThr: 5.534 ± 0.667
6.058GlyVal: 6.058 ± 0.695
1.421GlyTrp: 1.421 ± 0.323
3.365GlyTyr: 3.365 ± 0.428
0.0GlyXaa: 0.0 ± 0.0
His
1.72HisAla: 1.72 ± 0.44
0.374HisCys: 0.374 ± 0.144
0.823HisAsp: 0.823 ± 0.311
0.972HisGlu: 0.972 ± 0.257
0.449HisPhe: 0.449 ± 0.154
1.346HisGly: 1.346 ± 0.346
0.449HisHis: 0.449 ± 0.209
1.421HisIle: 1.421 ± 0.398
1.346HisLys: 1.346 ± 0.351
1.72HisLeu: 1.72 ± 0.388
0.299HisMet: 0.299 ± 0.163
0.524HisAsn: 0.524 ± 0.205
0.598HisPro: 0.598 ± 0.216
0.748HisGln: 0.748 ± 0.236
1.571HisArg: 1.571 ± 0.267
1.047HisSer: 1.047 ± 0.281
1.421HisThr: 1.421 ± 0.296
0.897HisVal: 0.897 ± 0.297
0.449HisTrp: 0.449 ± 0.199
0.374HisTyr: 0.374 ± 0.149
0.0HisXaa: 0.0 ± 0.0
Ile
5.086IleAla: 5.086 ± 0.843
0.374IleCys: 0.374 ± 0.174
3.515IleAsp: 3.515 ± 0.439
3.066IleGlu: 3.066 ± 0.432
1.496IlePhe: 1.496 ± 0.321
3.515IleGly: 3.515 ± 0.45
0.673IleHis: 0.673 ± 0.202
1.87IleIle: 1.87 ± 0.355
3.066IleLys: 3.066 ± 0.537
2.917IleLeu: 2.917 ± 0.602
1.421IleMet: 1.421 ± 0.426
2.543IleAsn: 2.543 ± 0.411
2.244IlePro: 2.244 ± 0.522
1.346IleGln: 1.346 ± 0.316
2.767IleArg: 2.767 ± 0.485
3.515IleSer: 3.515 ± 0.613
3.665IleThr: 3.665 ± 0.431
3.291IleVal: 3.291 ± 0.506
0.673IleTrp: 0.673 ± 0.201
1.122IleTyr: 1.122 ± 0.363
0.0IleXaa: 0.0 ± 0.0
Lys
5.759LysAla: 5.759 ± 0.623
0.374LysCys: 0.374 ± 0.18
2.842LysAsp: 2.842 ± 0.454
2.543LysGlu: 2.543 ± 0.504
1.346LysPhe: 1.346 ± 0.314
4.113LysGly: 4.113 ± 0.576
1.047LysHis: 1.047 ± 0.269
2.692LysIle: 2.692 ± 0.545
3.515LysLys: 3.515 ± 0.44
5.086LysLeu: 5.086 ± 0.698
1.346LysMet: 1.346 ± 0.294
1.271LysAsn: 1.271 ± 0.289
1.795LysPro: 1.795 ± 0.373
3.365LysGln: 3.365 ± 0.548
2.842LysArg: 2.842 ± 0.549
2.692LysSer: 2.692 ± 0.583
2.618LysThr: 2.618 ± 0.403
3.889LysVal: 3.889 ± 0.535
1.197LysTrp: 1.197 ± 0.233
1.346LysTyr: 1.346 ± 0.281
0.0LysXaa: 0.0 ± 0.0
Leu
8.9LeuAla: 8.9 ± 0.793
0.673LeuCys: 0.673 ± 0.239
5.086LeuAsp: 5.086 ± 0.651
4.786LeuGlu: 4.786 ± 0.689
2.169LeuPhe: 2.169 ± 0.381
6.507LeuGly: 6.507 ± 0.541
1.87LeuHis: 1.87 ± 0.37
3.59LeuIle: 3.59 ± 0.742
3.889LeuLys: 3.889 ± 0.596
7.03LeuLeu: 7.03 ± 0.9
1.421LeuMet: 1.421 ± 0.348
3.365LeuAsn: 3.365 ± 0.531
3.59LeuPro: 3.59 ± 0.678
3.964LeuGln: 3.964 ± 0.803
7.03LeuArg: 7.03 ± 0.704
7.628LeuSer: 7.628 ± 1.005
5.609LeuThr: 5.609 ± 0.597
5.16LeuVal: 5.16 ± 0.514
0.972LeuTrp: 0.972 ± 0.265
2.543LeuTyr: 2.543 ± 0.398
0.0LeuXaa: 0.0 ± 0.0
Met
2.692MetAla: 2.692 ± 0.435
0.075MetCys: 0.075 ± 0.085
1.271MetAsp: 1.271 ± 0.336
1.047MetGlu: 1.047 ± 0.33
0.897MetPhe: 0.897 ± 0.258
0.897MetGly: 0.897 ± 0.182
0.598MetHis: 0.598 ± 0.23
1.197MetIle: 1.197 ± 0.331
0.823MetLys: 0.823 ± 0.215
2.019MetLeu: 2.019 ± 0.428
0.748MetMet: 0.748 ± 0.307
1.047MetAsn: 1.047 ± 0.312
1.571MetPro: 1.571 ± 0.411
1.421MetGln: 1.421 ± 0.329
1.496MetArg: 1.496 ± 0.292
2.618MetSer: 2.618 ± 0.503
1.87MetThr: 1.87 ± 0.448
1.197MetVal: 1.197 ± 0.31
0.224MetTrp: 0.224 ± 0.112
0.748MetTyr: 0.748 ± 0.324
0.0MetXaa: 0.0 ± 0.0
Asn
3.964AsnAla: 3.964 ± 0.539
0.449AsnCys: 0.449 ± 0.15
2.468AsnAsp: 2.468 ± 0.428
1.945AsnGlu: 1.945 ± 0.39
1.122AsnPhe: 1.122 ± 0.278
3.291AsnGly: 3.291 ± 0.549
0.598AsnHis: 0.598 ± 0.205
1.87AsnIle: 1.87 ± 0.339
2.692AsnLys: 2.692 ± 0.46
2.917AsnLeu: 2.917 ± 0.42
0.823AsnMet: 0.823 ± 0.254
2.318AsnAsn: 2.318 ± 0.476
2.169AsnPro: 2.169 ± 0.379
1.496AsnGln: 1.496 ± 0.348
2.244AsnArg: 2.244 ± 0.478
1.87AsnSer: 1.87 ± 0.428
2.543AsnThr: 2.543 ± 0.369
2.094AsnVal: 2.094 ± 0.386
0.224AsnTrp: 0.224 ± 0.103
1.346AsnTyr: 1.346 ± 0.405
0.0AsnXaa: 0.0 ± 0.0
Pro
4.413ProAla: 4.413 ± 0.54
0.15ProCys: 0.15 ± 0.113
3.515ProAsp: 3.515 ± 0.546
3.141ProGlu: 3.141 ± 0.671
1.197ProPhe: 1.197 ± 0.353
4.487ProGly: 4.487 ± 0.621
0.598ProHis: 0.598 ± 0.2
1.346ProIle: 1.346 ± 0.321
2.318ProLys: 2.318 ± 0.464
2.692ProLeu: 2.692 ± 0.57
0.823ProMet: 0.823 ± 0.246
1.271ProAsn: 1.271 ± 0.263
2.019ProPro: 2.019 ± 0.466
1.421ProGln: 1.421 ± 0.322
1.421ProArg: 1.421 ± 0.308
2.244ProSer: 2.244 ± 0.344
2.169ProThr: 2.169 ± 0.446
2.543ProVal: 2.543 ± 0.444
0.449ProTrp: 0.449 ± 0.152
0.897ProTyr: 0.897 ± 0.248
0.0ProXaa: 0.0 ± 0.0
Gln
6.806GlnAla: 6.806 ± 0.656
0.299GlnCys: 0.299 ± 0.15
2.244GlnAsp: 2.244 ± 0.376
1.72GlnGlu: 1.72 ± 0.4
1.571GlnPhe: 1.571 ± 0.288
3.59GlnGly: 3.59 ± 0.539
0.673GlnHis: 0.673 ± 0.247
3.291GlnIle: 3.291 ± 0.637
1.421GlnLys: 1.421 ± 0.577
4.786GlnLeu: 4.786 ± 0.517
1.571GlnMet: 1.571 ± 0.339
1.421GlnAsn: 1.421 ± 0.29
1.795GlnPro: 1.795 ± 0.307
2.767GlnGln: 2.767 ± 0.492
2.842GlnArg: 2.842 ± 0.439
2.468GlnSer: 2.468 ± 0.654
2.917GlnThr: 2.917 ± 0.573
4.263GlnVal: 4.263 ± 0.637
0.598GlnTrp: 0.598 ± 0.191
1.645GlnTyr: 1.645 ± 0.312
0.0GlnXaa: 0.0 ± 0.0
Arg
5.684ArgAla: 5.684 ± 0.648
0.598ArgCys: 0.598 ± 0.233
2.692ArgAsp: 2.692 ± 0.391
3.44ArgGlu: 3.44 ± 0.56
1.571ArgPhe: 1.571 ± 0.446
3.964ArgGly: 3.964 ± 0.481
1.122ArgHis: 1.122 ± 0.31
3.739ArgIle: 3.739 ± 0.515
3.44ArgLys: 3.44 ± 0.63
5.086ArgLeu: 5.086 ± 0.709
1.047ArgMet: 1.047 ± 0.311
1.72ArgAsn: 1.72 ± 0.314
2.393ArgPro: 2.393 ± 0.484
2.767ArgGln: 2.767 ± 0.627
2.917ArgArg: 2.917 ± 0.503
3.739ArgSer: 3.739 ± 0.541
2.468ArgThr: 2.468 ± 0.345
5.16ArgVal: 5.16 ± 0.807
0.598ArgTrp: 0.598 ± 0.201
2.244ArgTyr: 2.244 ± 0.381
0.0ArgXaa: 0.0 ± 0.0
Ser
8.601SerAla: 8.601 ± 1.192
0.449SerCys: 0.449 ± 0.179
2.618SerAsp: 2.618 ± 0.37
3.216SerGlu: 3.216 ± 0.525
1.271SerPhe: 1.271 ± 0.232
7.03SerGly: 7.03 ± 1.022
0.823SerHis: 0.823 ± 0.23
3.291SerIle: 3.291 ± 0.477
3.739SerLys: 3.739 ± 0.446
5.235SerLeu: 5.235 ± 0.558
1.645SerMet: 1.645 ± 0.379
2.917SerAsn: 2.917 ± 0.432
2.244SerPro: 2.244 ± 0.384
2.917SerGln: 2.917 ± 0.382
2.842SerArg: 2.842 ± 0.487
4.712SerSer: 4.712 ± 0.516
5.31SerThr: 5.31 ± 0.698
6.432SerVal: 6.432 ± 0.946
1.421SerTrp: 1.421 ± 0.28
2.094SerTyr: 2.094 ± 0.385
0.0SerXaa: 0.0 ± 0.0
Thr
7.479ThrAla: 7.479 ± 1.172
0.524ThrCys: 0.524 ± 0.199
2.917ThrAsp: 2.917 ± 0.681
1.87ThrGlu: 1.87 ± 0.377
2.169ThrPhe: 2.169 ± 0.53
6.581ThrGly: 6.581 ± 0.703
1.122ThrHis: 1.122 ± 0.262
2.692ThrIle: 2.692 ± 0.453
3.066ThrLys: 3.066 ± 0.38
6.432ThrLeu: 6.432 ± 0.657
2.094ThrMet: 2.094 ± 0.444
1.496ThrAsn: 1.496 ± 0.32
2.692ThrPro: 2.692 ± 0.453
2.618ThrGln: 2.618 ± 0.449
2.917ThrArg: 2.917 ± 0.352
4.413ThrSer: 4.413 ± 0.854
3.889ThrThr: 3.889 ± 0.601
4.712ThrVal: 4.712 ± 0.857
0.897ThrTrp: 0.897 ± 0.351
1.645ThrTyr: 1.645 ± 0.382
0.0ThrXaa: 0.0 ± 0.0
Val
7.628ValAla: 7.628 ± 0.782
0.598ValCys: 0.598 ± 0.189
4.413ValAsp: 4.413 ± 0.716
4.188ValGlu: 4.188 ± 0.718
2.019ValPhe: 2.019 ± 0.339
4.413ValGly: 4.413 ± 0.595
1.645ValHis: 1.645 ± 0.396
2.244ValIle: 2.244 ± 0.378
3.141ValLys: 3.141 ± 0.508
5.46ValLeu: 5.46 ± 0.631
1.496ValMet: 1.496 ± 0.311
4.039ValAsn: 4.039 ± 0.547
3.066ValPro: 3.066 ± 0.577
4.338ValGln: 4.338 ± 0.622
3.665ValArg: 3.665 ± 0.651
5.16ValSer: 5.16 ± 0.578
4.338ValThr: 4.338 ± 0.737
4.861ValVal: 4.861 ± 0.649
0.823ValTrp: 0.823 ± 0.214
2.244ValTyr: 2.244 ± 0.495
0.0ValXaa: 0.0 ± 0.0
Trp
1.047TrpAla: 1.047 ± 0.277
0.449TrpCys: 0.449 ± 0.2
1.047TrpAsp: 1.047 ± 0.264
0.823TrpGlu: 0.823 ± 0.255
0.449TrpPhe: 0.449 ± 0.179
0.673TrpGly: 0.673 ± 0.188
0.748TrpHis: 0.748 ± 0.247
0.15TrpIle: 0.15 ± 0.108
0.823TrpLys: 0.823 ± 0.233
1.87TrpLeu: 1.87 ± 0.425
0.673TrpMet: 0.673 ± 0.265
0.598TrpAsn: 0.598 ± 0.185
0.972TrpPro: 0.972 ± 0.269
0.897TrpGln: 0.897 ± 0.295
1.645TrpArg: 1.645 ± 0.337
0.897TrpSer: 0.897 ± 0.237
0.823TrpThr: 0.823 ± 0.27
0.598TrpVal: 0.598 ± 0.173
0.15TrpTrp: 0.15 ± 0.11
0.673TrpTyr: 0.673 ± 0.204
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.216TyrAla: 3.216 ± 0.546
0.524TyrCys: 0.524 ± 0.214
1.945TyrAsp: 1.945 ± 0.351
1.122TyrGlu: 1.122 ± 0.291
1.496TyrPhe: 1.496 ± 0.287
2.842TyrGly: 2.842 ± 0.527
0.673TyrHis: 0.673 ± 0.22
1.346TyrIle: 1.346 ± 0.425
1.271TyrLys: 1.271 ± 0.273
2.992TyrLeu: 2.992 ± 0.434
0.449TyrMet: 0.449 ± 0.205
1.271TyrAsn: 1.271 ± 0.229
1.421TyrPro: 1.421 ± 0.351
1.346TyrGln: 1.346 ± 0.329
1.571TyrArg: 1.571 ± 0.259
3.216TyrSer: 3.216 ± 0.493
2.019TyrThr: 2.019 ± 0.419
1.795TyrVal: 1.795 ± 0.382
0.374TyrTrp: 0.374 ± 0.159
1.421TyrTyr: 1.421 ± 0.295
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 60 proteins (13372 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski