Amino acid dipepetide frequency for Colletotrichum graminicola (strain M1.001 / M2 / FGSC 10212) (Maize anthracnose fungus) (Glomerella graminicola)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	11.103AlaAla: 11.103 ± 0.075	1.136AlaCys: 1.136 ± 0.016	4.768AlaAsp: 4.768 ± 0.03	5.461AlaGlu: 5.461 ± 0.054	3.273AlaPhe: 3.273 ± 0.023	6.532AlaGly: 6.532 ± 0.043	1.814AlaHis: 1.814 ± 0.021	4.227AlaIle: 4.227 ± 0.028	4.301AlaLys: 4.301 ± 0.036	7.946AlaLeu: 7.946 ± 0.047	2.133AlaMet: 2.133 ± 0.02	3.108AlaAsn: 3.108 ± 0.023	5.332AlaPro: 5.332 ± 0.047	3.484AlaGln: 3.484 ± 0.031	5.258AlaArg: 5.258 ± 0.037	7.678AlaSer: 7.678 ± 0.044	5.608AlaThr: 5.608 ± 0.036	6.154AlaVal: 6.154 ± 0.041	1.29AlaTrp: 1.29 ± 0.016	2.253AlaTyr: 2.253 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	0.972CysAla: 0.972 ± 0.014	0.253CysCys: 0.253 ± 0.007	0.671CysAsp: 0.671 ± 0.012	0.561CysGlu: 0.561 ± 0.011	0.523CysPhe: 0.523 ± 0.01	0.992CysGly: 0.992 ± 0.017	0.315CysHis: 0.315 ± 0.008	0.675CysIle: 0.675 ± 0.011	0.513CysLys: 0.513 ± 0.011	1.187CysLeu: 1.187 ± 0.016	0.266CysMet: 0.266 ± 0.008	0.447CysAsn: 0.447 ± 0.009	0.658CysPro: 0.658 ± 0.011	0.428CysGln: 0.428 ± 0.009	0.764CysArg: 0.764 ± 0.012	0.873CysSer: 0.873 ± 0.014	0.657CysThr: 0.657 ± 0.011	0.792CysVal: 0.792 ± 0.011	0.206CysTrp: 0.206 ± 0.007	0.339CysTyr: 0.339 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	5.249AspAla: 5.249 ± 0.036	0.638AspCys: 0.638 ± 0.012	4.609AspAsp: 4.609 ± 0.041	4.511AspGlu: 4.511 ± 0.037	2.262AspPhe: 2.262 ± 0.02	4.433AspGly: 4.433 ± 0.035	1.179AspHis: 1.179 ± 0.015	2.883AspIle: 2.883 ± 0.025	2.524AspLys: 2.524 ± 0.026	4.926AspLeu: 4.926 ± 0.035	1.369AspMet: 1.369 ± 0.017	1.891AspAsn: 1.891 ± 0.02	3.356AspPro: 3.356 ± 0.027	1.772AspGln: 1.772 ± 0.02	3.077AspArg: 3.077 ± 0.031	3.922AspSer: 3.922 ± 0.033	2.854AspThr: 2.854 ± 0.023	3.879AspVal: 3.879 ± 0.029	0.897AspTrp: 0.897 ± 0.013	1.574AspTyr: 1.574 ± 0.018	0.0AspXaa: 0.0 ± 0.0
Glu	5.806GluAla: 5.806 ± 0.055	0.58GluCys: 0.58 ± 0.011	4.167GluAsp: 4.167 ± 0.035	5.2GluGlu: 5.2 ± 0.06	1.885GluPhe: 1.885 ± 0.02	3.795GluGly: 3.795 ± 0.032	1.342GluHis: 1.342 ± 0.016	2.751GluIle: 2.751 ± 0.024	3.6GluLys: 3.6 ± 0.033	4.992GluLeu: 4.992 ± 0.036	1.475GluMet: 1.475 ± 0.016	2.107GluAsn: 2.107 ± 0.02	2.884GluPro: 2.884 ± 0.045	2.287GluGln: 2.287 ± 0.028	3.85GluArg: 3.85 ± 0.033	3.991GluSer: 3.991 ± 0.035	3.46GluThr: 3.46 ± 0.039	3.613GluVal: 3.613 ± 0.037	0.877GluTrp: 0.877 ± 0.012	1.58GluTyr: 1.58 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	3.202PheAla: 3.202 ± 0.026	0.557PheCys: 0.557 ± 0.011	2.322PheAsp: 2.322 ± 0.023	2.099PheGlu: 2.099 ± 0.021	1.632PhePhe: 1.632 ± 0.02	2.969PheGly: 2.969 ± 0.027	0.852PheHis: 0.852 ± 0.013	1.732PheIle: 1.732 ± 0.019	1.491PheLys: 1.491 ± 0.018	3.361PheLeu: 3.361 ± 0.03	0.799PheMet: 0.799 ± 0.011	1.459PheAsn: 1.459 ± 0.016	1.901PhePro: 1.901 ± 0.021	1.335PheGln: 1.335 ± 0.015	1.989PheArg: 1.989 ± 0.018	2.898PheSer: 2.898 ± 0.023	2.116PheThr: 2.116 ± 0.021	2.493PheVal: 2.493 ± 0.023	0.652PheTrp: 0.652 ± 0.012	1.102PheTyr: 1.102 ± 0.016	0.0PheXaa: 0.0 ± 0.0
Gly	5.997GlyAla: 5.997 ± 0.042	0.91GlyCys: 0.91 ± 0.015	3.873GlyAsp: 3.873 ± 0.029	3.649GlyGlu: 3.649 ± 0.029	2.916GlyPhe: 2.916 ± 0.025	6.628GlyGly: 6.628 ± 0.062	1.769GlyHis: 1.769 ± 0.019	3.523GlyIle: 3.523 ± 0.032	3.452GlyLys: 3.452 ± 0.029	6.278GlyLeu: 6.278 ± 0.04	1.661GlyMet: 1.661 ± 0.02	2.666GlyAsn: 2.666 ± 0.026	3.602GlyPro: 3.602 ± 0.031	2.617GlyGln: 2.617 ± 0.023	4.378GlyArg: 4.378 ± 0.037	5.878GlySer: 5.878 ± 0.046	4.171GlyThr: 4.171 ± 0.042	4.665GlyVal: 4.665 ± 0.04	1.224GlyTrp: 1.224 ± 0.016	2.138GlyTyr: 2.138 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	1.861HisAla: 1.861 ± 0.021	0.334HisCys: 0.334 ± 0.008	1.288HisAsp: 1.288 ± 0.015	1.268HisGlu: 1.268 ± 0.015	0.896HisPhe: 0.896 ± 0.015	1.728HisGly: 1.728 ± 0.021	0.851HisHis: 0.851 ± 0.019	1.122HisIle: 1.122 ± 0.016	0.894HisLys: 0.894 ± 0.014	2.113HisLeu: 2.113 ± 0.022	0.528HisMet: 0.528 ± 0.01	0.802HisAsn: 0.802 ± 0.013	1.589HisPro: 1.589 ± 0.019	0.979HisGln: 0.979 ± 0.019	1.481HisArg: 1.481 ± 0.018	1.693HisSer: 1.693 ± 0.019	1.179HisThr: 1.179 ± 0.014	1.476HisVal: 1.476 ± 0.019	0.344HisTrp: 0.344 ± 0.007	0.676HisTyr: 0.676 ± 0.011	0.0HisXaa: 0.0 ± 0.0
Ile	4.148IleAla: 4.148 ± 0.029	0.679IleCys: 0.679 ± 0.012	2.709IleAsp: 2.709 ± 0.025	2.666IleGlu: 2.666 ± 0.023	1.894IlePhe: 1.894 ± 0.022	3.161IleGly: 3.161 ± 0.029	1.102IleHis: 1.102 ± 0.018	2.342IleIle: 2.342 ± 0.026	2.111IleLys: 2.111 ± 0.021	4.177IleLeu: 4.177 ± 0.035	1.003IleMet: 1.003 ± 0.016	1.708IleAsn: 1.708 ± 0.018	2.832IlePro: 2.832 ± 0.025	1.723IleGln: 1.723 ± 0.017	2.654IleArg: 2.654 ± 0.025	3.493IleSer: 3.493 ± 0.026	2.706IleThr: 2.706 ± 0.022	3.178IleVal: 3.178 ± 0.027	0.699IleTrp: 0.699 ± 0.012	1.296IleTyr: 1.296 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	4.493LysAla: 4.493 ± 0.036	0.491LysCys: 0.491 ± 0.009	2.793LysAsp: 2.793 ± 0.027	3.246LysGlu: 3.246 ± 0.037	1.406LysPhe: 1.406 ± 0.018	3.037LysGly: 3.037 ± 0.027	1.085LysHis: 1.085 ± 0.014	2.096LysIle: 2.096 ± 0.021	3.419LysLys: 3.419 ± 0.056	3.999LysLeu: 3.999 ± 0.034	1.067LysMet: 1.067 ± 0.012	1.71LysAsn: 1.71 ± 0.022	2.779LysPro: 2.779 ± 0.029	1.756LysGln: 1.756 ± 0.022	3.274LysArg: 3.274 ± 0.03	3.362LysSer: 3.362 ± 0.03	2.927LysThr: 2.927 ± 0.025	2.829LysVal: 2.829 ± 0.026	0.674LysTrp: 0.674 ± 0.013	1.307LysTyr: 1.307 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	8.232LeuAla: 8.232 ± 0.046	1.149LeuCys: 1.149 ± 0.016	5.063LeuAsp: 5.063 ± 0.031	5.284LeuGlu: 5.284 ± 0.043	3.222LeuPhe: 3.222 ± 0.028	6.119LeuGly: 6.119 ± 0.039	2.069LeuHis: 2.069 ± 0.02	3.64LeuIle: 3.64 ± 0.03	3.99LeuLys: 3.99 ± 0.035	8.029LeuLeu: 8.029 ± 0.057	1.807LeuMet: 1.807 ± 0.019	2.97LeuAsn: 2.97 ± 0.023	5.426LeuPro: 5.426 ± 0.042	3.547LeuGln: 3.547 ± 0.03	5.667LeuArg: 5.667 ± 0.041	6.827LeuSer: 6.827 ± 0.043	4.737LeuThr: 4.737 ± 0.03	5.657LeuVal: 5.657 ± 0.039	1.21LeuTrp: 1.21 ± 0.015	2.227LeuTyr: 2.227 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	2.484MetAla: 2.484 ± 0.021	0.236MetCys: 0.236 ± 0.007	1.269MetAsp: 1.269 ± 0.016	1.258MetGlu: 1.258 ± 0.017	0.76MetPhe: 0.76 ± 0.011	1.539MetGly: 1.539 ± 0.019	0.467MetHis: 0.467 ± 0.009	0.96MetIle: 0.96 ± 0.016	1.025MetLys: 1.025 ± 0.014	1.862MetLeu: 1.862 ± 0.019	0.627MetMet: 0.627 ± 0.012	0.792MetAsn: 0.792 ± 0.014	1.387MetPro: 1.387 ± 0.02	0.838MetGln: 0.838 ± 0.013	1.338MetArg: 1.338 ± 0.015	1.93MetSer: 1.93 ± 0.02	1.362MetThr: 1.362 ± 0.018	1.356MetVal: 1.356 ± 0.017	0.281MetTrp: 0.281 ± 0.007	0.543MetTyr: 0.543 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.156AsnAla: 3.156 ± 0.023	0.426AsnCys: 0.426 ± 0.01	1.961AsnAsp: 1.961 ± 0.021	1.931AsnGlu: 1.931 ± 0.021	1.36AsnPhe: 1.36 ± 0.015	3.089AsnGly: 3.089 ± 0.026	0.816AsnHis: 0.816 ± 0.014	1.909AsnIle: 1.909 ± 0.019	1.596AsnLys: 1.596 ± 0.019	3.134AsnLeu: 3.134 ± 0.022	0.868AsnMet: 0.868 ± 0.013	1.503AsnAsn: 1.503 ± 0.021	2.404AsnPro: 2.404 ± 0.021	1.273AsnGln: 1.273 ± 0.019	1.868AsnArg: 1.868 ± 0.021	2.587AsnSer: 2.587 ± 0.022	2.094AsnThr: 2.094 ± 0.021	2.288AsnVal: 2.288 ± 0.021	0.565AsnTrp: 0.565 ± 0.011	1.027AsnTyr: 1.027 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	5.924ProAla: 5.924 ± 0.058	0.515ProCys: 0.515 ± 0.011	3.319ProAsp: 3.319 ± 0.024	3.877ProGlu: 3.877 ± 0.035	2.066ProPhe: 2.066 ± 0.021	4.264ProGly: 4.264 ± 0.039	1.275ProHis: 1.275 ± 0.019	2.409ProIle: 2.409 ± 0.023	2.719ProLys: 2.719 ± 0.028	4.661ProLeu: 4.661 ± 0.035	1.125ProMet: 1.125 ± 0.016	2.151ProAsn: 2.151 ± 0.021	5.529ProPro: 5.529 ± 0.073	2.446ProGln: 2.446 ± 0.034	3.553ProArg: 3.553 ± 0.037	5.795ProSer: 5.795 ± 0.047	4.016ProThr: 4.016 ± 0.04	3.833ProVal: 3.833 ± 0.034	0.771ProTrp: 0.771 ± 0.013	1.471ProTyr: 1.471 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.514GlnAla: 3.514 ± 0.032	0.425GlnCys: 0.425 ± 0.009	2.019GlnAsp: 2.019 ± 0.021	2.253GlnGlu: 2.253 ± 0.022	1.209GlnPhe: 1.209 ± 0.014	2.411GlnGly: 2.411 ± 0.021	1.059GlnHis: 1.059 ± 0.017	1.705GlnIle: 1.705 ± 0.019	1.892GlnLys: 1.892 ± 0.022	3.274GlnLeu: 3.274 ± 0.028	0.91GlnMet: 0.91 ± 0.016	1.426GlnAsn: 1.426 ± 0.016	2.551GlnPro: 2.551 ± 0.032	2.721GlnGln: 2.721 ± 0.063	2.538GlnArg: 2.538 ± 0.026	2.885GlnSer: 2.885 ± 0.025	2.272GlnThr: 2.272 ± 0.03	2.144GlnVal: 2.144 ± 0.022	0.558GlnTrp: 0.558 ± 0.011	1.115GlnTyr: 1.115 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	4.902ArgAla: 4.902 ± 0.038	0.723ArgCys: 0.723 ± 0.011	3.535ArgAsp: 3.535 ± 0.032	3.787ArgGlu: 3.787 ± 0.03	2.135ArgPhe: 2.135 ± 0.02	3.916ArgGly: 3.916 ± 0.035	1.614ArgHis: 1.614 ± 0.018	2.717ArgIle: 2.717 ± 0.022	3.335ArgLys: 3.335 ± 0.033	5.405ArgLeu: 5.405 ± 0.034	1.333ArgMet: 1.333 ± 0.016	2.214ArgAsn: 2.214 ± 0.019	3.731ArgPro: 3.731 ± 0.036	2.642ArgGln: 2.642 ± 0.026	5.234ArgArg: 5.234 ± 0.051	4.645ArgSer: 4.645 ± 0.043	3.242ArgThr: 3.242 ± 0.026	3.516ArgVal: 3.516 ± 0.028	0.957ArgTrp: 0.957 ± 0.012	1.603ArgTyr: 1.603 ± 0.018	0.0ArgXaa: 0.0 ± 0.0
Ser	6.948SerAla: 6.948 ± 0.044	0.857SerCys: 0.857 ± 0.014	4.076SerAsp: 4.076 ± 0.035	3.896SerGlu: 3.896 ± 0.033	2.983SerPhe: 2.983 ± 0.023	5.715SerGly: 5.715 ± 0.043	1.821SerHis: 1.821 ± 0.022	3.694SerIle: 3.694 ± 0.029	3.517SerLys: 3.517 ± 0.031	6.808SerLeu: 6.808 ± 0.041	1.747SerMet: 1.747 ± 0.019	2.813SerAsn: 2.813 ± 0.025	5.406SerPro: 5.406 ± 0.054	3.079SerGln: 3.079 ± 0.03	4.908SerArg: 4.908 ± 0.04	8.11SerSer: 8.11 ± 0.069	5.173SerThr: 5.173 ± 0.041	4.693SerVal: 4.693 ± 0.034	1.1SerTrp: 1.1 ± 0.015	1.992SerTyr: 1.992 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	5.558ThrAla: 5.558 ± 0.046	0.742ThrCys: 0.742 ± 0.012	2.866ThrAsp: 2.866 ± 0.022	3.061ThrGlu: 3.061 ± 0.03	2.183ThrPhe: 2.183 ± 0.022	4.316ThrGly: 4.316 ± 0.039	1.204ThrHis: 1.204 ± 0.015	2.955ThrIle: 2.955 ± 0.028	2.584ThrLys: 2.584 ± 0.029	5.005ThrLeu: 5.005 ± 0.031	1.201ThrMet: 1.201 ± 0.016	2.08ThrAsn: 2.08 ± 0.02	4.437ThrPro: 4.437 ± 0.043	2.031ThrGln: 2.031 ± 0.02	3.13ThrArg: 3.13 ± 0.027	5.092ThrSer: 5.092 ± 0.047	4.333ThrThr: 4.333 ± 0.055	3.892ThrVal: 3.892 ± 0.05	0.87ThrTrp: 0.87 ± 0.014	1.607ThrTyr: 1.607 ± 0.019	0.0ThrXaa: 0.0 ± 0.0
Val	5.907ValAla: 5.907 ± 0.037	0.84ValCys: 0.84 ± 0.015	3.875ValAsp: 3.875 ± 0.031	3.906ValGlu: 3.906 ± 0.036	2.628ValPhe: 2.628 ± 0.025	4.265ValGly: 4.265 ± 0.039	1.363ValHis: 1.363 ± 0.019	2.936ValIle: 2.936 ± 0.026	2.944ValLys: 2.944 ± 0.03	5.806ValLeu: 5.806 ± 0.038	1.389ValMet: 1.389 ± 0.016	2.254ValAsn: 2.254 ± 0.022	3.842ValPro: 3.842 ± 0.028	2.328ValGln: 2.328 ± 0.021	3.628ValArg: 3.628 ± 0.034	4.705ValSer: 4.705 ± 0.031	3.747ValThr: 3.747 ± 0.035	4.71ValVal: 4.71 ± 0.045	0.944ValTrp: 0.944 ± 0.015	1.762ValTyr: 1.762 ± 0.02	0.0ValXaa: 0.0 ± 0.0
Trp	1.224TrpAla: 1.224 ± 0.016	0.197TrpCys: 0.197 ± 0.005	0.942TrpAsp: 0.942 ± 0.015	0.839TrpGlu: 0.839 ± 0.013	0.57TrpPhe: 0.57 ± 0.011	0.985TrpGly: 0.985 ± 0.015	0.366TrpHis: 0.366 ± 0.009	0.72TrpIle: 0.72 ± 0.013	0.771TrpLys: 0.771 ± 0.011	1.366TrpLeu: 1.366 ± 0.017	0.387TrpMet: 0.387 ± 0.008	0.655TrpAsn: 0.655 ± 0.012	0.638TrpPro: 0.638 ± 0.011	0.575TrpGln: 0.575 ± 0.011	0.99TrpArg: 0.99 ± 0.016	1.043TrpSer: 1.043 ± 0.014	0.929TrpThr: 0.929 ± 0.015	0.93TrpVal: 0.93 ± 0.014	0.299TrpTrp: 0.299 ± 0.008	0.44TrpTyr: 0.44 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.178TyrAla: 2.178 ± 0.022	0.405TyrCys: 0.405 ± 0.008	1.677TyrAsp: 1.677 ± 0.018	1.488TyrGlu: 1.488 ± 0.018	1.157TyrPhe: 1.157 ± 0.016	2.101TyrGly: 2.101 ± 0.023	0.738TyrHis: 0.738 ± 0.012	1.286TyrIle: 1.286 ± 0.018	1.071TyrLys: 1.071 ± 0.017	2.542TyrLeu: 2.542 ± 0.025	0.62TyrMet: 0.62 ± 0.011	1.1TyrAsn: 1.1 ± 0.016	1.434TyrPro: 1.434 ± 0.019	1.023TyrGln: 1.023 ± 0.014	1.61TyrArg: 1.61 ± 0.017	1.928TyrSer: 1.928 ± 0.023	1.564TyrThr: 1.564 ± 0.022	1.682TyrVal: 1.682 ± 0.018	0.448TyrTrp: 0.448 ± 0.009	0.907TyrTyr: 0.907 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 12019 proteins (5585661 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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