Amino acid dipepetide frequency for Enterococcus pallens ATCC BAA-351

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.661AlaAla: 6.661 ± 0.098	0.619AlaCys: 0.619 ± 0.02	3.883AlaAsp: 3.883 ± 0.054	5.397AlaGlu: 5.397 ± 0.073	3.19AlaPhe: 3.19 ± 0.046	5.384AlaGly: 5.384 ± 0.075	1.145AlaHis: 1.145 ± 0.029	5.836AlaIle: 5.836 ± 0.071	4.966AlaLys: 4.966 ± 0.06	7.076AlaLeu: 7.076 ± 0.088	2.096AlaMet: 2.096 ± 0.044	3.022AlaAsn: 3.022 ± 0.055	2.246AlaPro: 2.246 ± 0.051	2.83AlaGln: 2.83 ± 0.047	2.32AlaArg: 2.32 ± 0.041	4.115AlaSer: 4.115 ± 0.062	4.076AlaThr: 4.076 ± 0.06	5.329AlaVal: 5.329 ± 0.067	0.631AlaTrp: 0.631 ± 0.019	2.444AlaTyr: 2.444 ± 0.039	0.0AlaXaa: 0.0 ± 0.0
Cys	0.438CysAla: 0.438 ± 0.019	0.096CysCys: 0.096 ± 0.009	0.372CysAsp: 0.372 ± 0.016	0.464CysGlu: 0.464 ± 0.017	0.391CysPhe: 0.391 ± 0.017	0.671CysGly: 0.671 ± 0.025	0.17CysHis: 0.17 ± 0.012	0.535CysIle: 0.535 ± 0.02	0.308CysLys: 0.308 ± 0.015	0.85CysLeu: 0.85 ± 0.023	0.182CysMet: 0.182 ± 0.011	0.241CysAsn: 0.241 ± 0.012	0.303CysPro: 0.303 ± 0.015	0.317CysGln: 0.317 ± 0.014	0.28CysArg: 0.28 ± 0.015	0.509CysSer: 0.509 ± 0.017	0.368CysThr: 0.368 ± 0.017	0.424CysVal: 0.424 ± 0.019	0.08CysTrp: 0.08 ± 0.007	0.282CysTyr: 0.282 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	3.285AspAla: 3.285 ± 0.05	0.408AspCys: 0.408 ± 0.017	2.44AspAsp: 2.44 ± 0.054	4.159AspGlu: 4.159 ± 0.054	2.696AspPhe: 2.696 ± 0.048	3.442AspGly: 3.442 ± 0.049	1.029AspHis: 1.029 ± 0.03	3.573AspIle: 3.573 ± 0.051	3.06AspLys: 3.06 ± 0.05	4.982AspLeu: 4.982 ± 0.066	1.302AspMet: 1.302 ± 0.032	2.104AspAsn: 2.104 ± 0.043	2.085AspPro: 2.085 ± 0.035	2.671AspGln: 2.671 ± 0.048	2.098AspArg: 2.098 ± 0.043	3.811AspSer: 3.811 ± 0.227	2.777AspThr: 2.777 ± 0.046	3.279AspVal: 3.279 ± 0.048	0.654AspTrp: 0.654 ± 0.021	2.652AspTyr: 2.652 ± 0.048	0.0AspXaa: 0.0 ± 0.0
Glu	5.888GluAla: 5.888 ± 0.076	0.386GluCys: 0.386 ± 0.017	3.735GluAsp: 3.735 ± 0.047	6.914GluGlu: 6.914 ± 0.093	2.5GluPhe: 2.5 ± 0.046	3.973GluGly: 3.973 ± 0.051	1.19GluHis: 1.19 ± 0.027	5.37GluIle: 5.37 ± 0.069	6.34GluLys: 6.34 ± 0.085	7.392GluLeu: 7.392 ± 0.085	2.174GluMet: 2.174 ± 0.035	3.921GluAsn: 3.921 ± 0.055	2.096GluPro: 2.096 ± 0.038	3.526GluGln: 3.526 ± 0.052	3.086GluArg: 3.086 ± 0.049	3.578GluSer: 3.578 ± 0.083	4.304GluThr: 4.304 ± 0.058	4.853GluVal: 4.853 ± 0.062	0.67GluTrp: 0.67 ± 0.018	2.357GluTyr: 2.357 ± 0.041	0.0GluXaa: 0.0 ± 0.0
Phe	3.116PheAla: 3.116 ± 0.051	0.424PheCys: 0.424 ± 0.017	2.593PheAsp: 2.593 ± 0.044	2.805PheGlu: 2.805 ± 0.047	2.412PhePhe: 2.412 ± 0.046	3.12PheGly: 3.12 ± 0.05	0.804PheHis: 0.804 ± 0.024	3.311PheIle: 3.311 ± 0.05	2.144PheLys: 2.144 ± 0.041	4.69PheLeu: 4.69 ± 0.066	1.074PheMet: 1.074 ± 0.028	1.935PheAsn: 1.935 ± 0.033	1.655PhePro: 1.655 ± 0.032	1.786PheGln: 1.786 ± 0.033	1.43PheArg: 1.43 ± 0.03	3.377PheSer: 3.377 ± 0.051	2.58PheThr: 2.58 ± 0.038	3.15PheVal: 3.15 ± 0.051	0.466PheTrp: 0.466 ± 0.018	1.912PheTyr: 1.912 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	4.559GlyAla: 4.559 ± 0.067	0.562GlyCys: 0.562 ± 0.02	3.108GlyAsp: 3.108 ± 0.048	4.225GlyGlu: 4.225 ± 0.059	3.118GlyPhe: 3.118 ± 0.042	4.38GlyGly: 4.38 ± 0.071	1.074GlyHis: 1.074 ± 0.027	5.784GlyIle: 5.784 ± 0.071	4.676GlyLys: 4.676 ± 0.053	6.316GlyLeu: 6.316 ± 0.07	1.991GlyMet: 1.991 ± 0.04	3.041GlyAsn: 3.041 ± 0.059	1.489GlyPro: 1.489 ± 0.036	2.368GlyGln: 2.368 ± 0.038	2.288GlyArg: 2.288 ± 0.04	4.023GlySer: 4.023 ± 0.054	4.083GlyThr: 4.083 ± 0.068	4.578GlyVal: 4.578 ± 0.069	0.739GlyTrp: 0.739 ± 0.022	2.751GlyTyr: 2.751 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	1.083HisAla: 1.083 ± 0.025	0.186HisCys: 0.186 ± 0.012	0.829HisAsp: 0.829 ± 0.027	1.168HisGlu: 1.168 ± 0.027	1.012HisPhe: 1.012 ± 0.026	1.2HisGly: 1.2 ± 0.031	0.447HisHis: 0.447 ± 0.017	1.066HisIle: 1.066 ± 0.03	0.805HisLys: 0.805 ± 0.025	1.885HisLeu: 1.885 ± 0.036	0.416HisMet: 0.416 ± 0.015	0.633HisAsn: 0.633 ± 0.022	0.879HisPro: 0.879 ± 0.028	0.922HisGln: 0.922 ± 0.024	0.751HisArg: 0.751 ± 0.025	1.055HisSer: 1.055 ± 0.024	0.908HisThr: 0.908 ± 0.024	1.042HisVal: 1.042 ± 0.023	0.219HisTrp: 0.219 ± 0.012	0.892HisTyr: 0.892 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.865IleAla: 5.865 ± 0.074	0.705IleCys: 0.705 ± 0.022	4.309IleAsp: 4.309 ± 0.061	5.202IleGlu: 5.202 ± 0.072	3.216IlePhe: 3.216 ± 0.058	5.263IleGly: 5.263 ± 0.068	1.413IleHis: 1.413 ± 0.032	5.048IleIle: 5.048 ± 0.072	4.143IleLys: 4.143 ± 0.057	6.8IleLeu: 6.8 ± 0.071	1.624IleMet: 1.624 ± 0.036	3.345IleAsn: 3.345 ± 0.051	3.335IlePro: 3.335 ± 0.058	3.411IleGln: 3.411 ± 0.088	3.055IleArg: 3.055 ± 0.069	4.81IleSer: 4.81 ± 0.074	4.302IleThr: 4.302 ± 0.061	5.315IleVal: 5.315 ± 0.077	0.554IleTrp: 0.554 ± 0.02	2.482IleTyr: 2.482 ± 0.039	0.0IleXaa: 0.0 ± 0.0
Lys	4.64LysAla: 4.64 ± 0.062	0.235LysCys: 0.235 ± 0.012	3.765LysAsp: 3.765 ± 0.05	6.482LysGlu: 6.482 ± 0.072	1.894LysPhe: 1.894 ± 0.036	3.757LysGly: 3.757 ± 0.044	1.037LysHis: 1.037 ± 0.024	4.621LysIle: 4.621 ± 0.055	5.877LysLys: 5.877 ± 0.074	5.707LysLeu: 5.707 ± 0.058	1.965LysMet: 1.965 ± 0.04	3.651LysAsn: 3.651 ± 0.051	1.954LysPro: 1.954 ± 0.034	3.44LysGln: 3.44 ± 0.06	3.08LysArg: 3.08 ± 0.049	3.074LysSer: 3.074 ± 0.048	3.581LysThr: 3.581 ± 0.05	4.279LysVal: 4.279 ± 0.056	0.544LysTrp: 0.544 ± 0.021	2.247LysTyr: 2.247 ± 0.044	0.0LysXaa: 0.0 ± 0.0
Leu	8.176LeuAla: 8.176 ± 0.08	0.767LeuCys: 0.767 ± 0.024	4.863LeuAsp: 4.863 ± 0.065	6.505LeuGlu: 6.505 ± 0.067	4.797LeuPhe: 4.797 ± 0.068	6.404LeuGly: 6.404 ± 0.072	1.583LeuHis: 1.583 ± 0.035	7.12LeuIle: 7.12 ± 0.077	6.284LeuLys: 6.284 ± 0.067	10.827LeuLeu: 10.827 ± 0.119	2.565LeuMet: 2.565 ± 0.039	4.415LeuAsn: 4.415 ± 0.056	4.122LeuPro: 4.122 ± 0.054	3.703LeuGln: 3.703 ± 0.052	3.621LeuArg: 3.621 ± 0.053	7.092LeuSer: 7.092 ± 0.081	6.289LeuThr: 6.289 ± 0.077	6.674LeuVal: 6.674 ± 0.069	0.778LeuTrp: 0.778 ± 0.024	3.06LeuTyr: 3.06 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	1.932MetAla: 1.932 ± 0.04	0.156MetCys: 0.156 ± 0.009	1.39MetAsp: 1.39 ± 0.027	1.824MetGlu: 1.824 ± 0.034	0.895MetPhe: 0.895 ± 0.025	1.758MetGly: 1.758 ± 0.036	0.393MetHis: 0.393 ± 0.016	2.226MetIle: 2.226 ± 0.042	2.244MetLys: 2.244 ± 0.036	2.348MetLeu: 2.348 ± 0.039	0.813MetMet: 0.813 ± 0.025	1.543MetAsn: 1.543 ± 0.033	0.963MetPro: 0.963 ± 0.024	0.949MetGln: 0.949 ± 0.025	0.995MetArg: 0.995 ± 0.03	1.542MetSer: 1.542 ± 0.031	1.732MetThr: 1.732 ± 0.032	1.704MetVal: 1.704 ± 0.03	0.155MetTrp: 0.155 ± 0.01	0.751MetTyr: 0.751 ± 0.024	0.0MetXaa: 0.0 ± 0.0
Asn	2.786AsnAla: 2.786 ± 0.047	0.37AsnCys: 0.37 ± 0.017	2.452AsnAsp: 2.452 ± 0.038	3.248AsnGlu: 3.248 ± 0.052	1.923AsnPhe: 1.923 ± 0.033	3.234AsnGly: 3.234 ± 0.052	0.95AsnHis: 0.95 ± 0.027	2.954AsnIle: 2.954 ± 0.048	2.773AsnLys: 2.773 ± 0.044	4.316AsnLeu: 4.316 ± 0.053	1.084AsnMet: 1.084 ± 0.026	2.156AsnAsn: 2.156 ± 0.046	2.094AsnPro: 2.094 ± 0.044	2.744AsnGln: 2.744 ± 0.043	1.94AsnArg: 1.94 ± 0.037	2.659AsnSer: 2.659 ± 0.051	2.342AsnThr: 2.342 ± 0.043	2.869AsnVal: 2.869 ± 0.041	0.538AsnTrp: 0.538 ± 0.017	2.116AsnTyr: 2.116 ± 0.04	0.0AsnXaa: 0.0 ± 0.0
Pro	2.804ProAla: 2.804 ± 0.042	0.189ProCys: 0.189 ± 0.011	2.013ProAsp: 2.013 ± 0.042	3.342ProGlu: 3.342 ± 0.055	1.8ProPhe: 1.8 ± 0.034	1.977ProGly: 1.977 ± 0.04	0.642ProHis: 0.642 ± 0.02	2.922ProIle: 2.922 ± 0.057	2.209ProLys: 2.209 ± 0.04	3.434ProLeu: 3.434 ± 0.051	0.92ProMet: 0.92 ± 0.023	1.734ProAsn: 1.734 ± 0.04	0.855ProPro: 0.855 ± 0.027	1.381ProGln: 1.381 ± 0.032	1.041ProArg: 1.041 ± 0.027	2.066ProSer: 2.066 ± 0.035	2.222ProThr: 2.222 ± 0.045	2.747ProVal: 2.747 ± 0.046	0.312ProTrp: 0.312 ± 0.013	1.309ProTyr: 1.309 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	3.679GlnAla: 3.679 ± 0.062	0.184GlnCys: 0.184 ± 0.01	1.742GlnAsp: 1.742 ± 0.037	3.669GlnGlu: 3.669 ± 0.061	1.67GlnPhe: 1.67 ± 0.034	2.346GlnGly: 2.346 ± 0.041	0.749GlnHis: 0.749 ± 0.023	3.042GlnIle: 3.042 ± 0.075	3.173GlnLys: 3.173 ± 0.053	5.394GlnLeu: 5.394 ± 0.08	1.176GlnMet: 1.176 ± 0.023	1.673GlnAsn: 1.673 ± 0.034	1.598GlnPro: 1.598 ± 0.037	2.855GlnGln: 2.855 ± 0.071	1.922GlnArg: 1.922 ± 0.043	2.281GlnSer: 2.281 ± 0.039	2.869GlnThr: 2.869 ± 0.087	3.104GlnVal: 3.104 ± 0.049	0.432GlnTrp: 0.432 ± 0.016	1.304GlnTyr: 1.304 ± 0.031	0.0GlnXaa: 0.0 ± 0.0
Arg	2.145ArgAla: 2.145 ± 0.04	0.274ArgCys: 0.274 ± 0.014	1.749ArgAsp: 1.749 ± 0.034	2.909ArgGlu: 2.909 ± 0.045	1.847ArgPhe: 1.847 ± 0.034	2.02ArgGly: 2.02 ± 0.033	0.656ArgHis: 0.656 ± 0.02	3.154ArgIle: 3.154 ± 0.062	3.048ArgLys: 3.048 ± 0.051	3.947ArgLeu: 3.947 ± 0.05	1.143ArgMet: 1.143 ± 0.029	1.8ArgAsn: 1.8 ± 0.037	1.257ArgPro: 1.257 ± 0.037	1.771ArgGln: 1.771 ± 0.036	1.769ArgArg: 1.769 ± 0.037	2.087ArgSer: 2.087 ± 0.04	2.195ArgThr: 2.195 ± 0.069	2.427ArgVal: 2.427 ± 0.046	0.393ArgTrp: 0.393 ± 0.017	1.698ArgTyr: 1.698 ± 0.034	0.0ArgXaa: 0.0 ± 0.0
Ser	3.961SerAla: 3.961 ± 0.058	0.437SerCys: 0.437 ± 0.015	3.882SerAsp: 3.882 ± 0.214	4.237SerGlu: 4.237 ± 0.081	3.14SerPhe: 3.14 ± 0.05	4.39SerGly: 4.39 ± 0.067	1.003SerHis: 1.003 ± 0.026	4.558SerIle: 4.558 ± 0.064	3.566SerLys: 3.566 ± 0.046	6.269SerLeu: 6.269 ± 0.067	1.605SerMet: 1.605 ± 0.034	2.671SerAsn: 2.671 ± 0.051	2.02SerPro: 2.02 ± 0.04	2.496SerGln: 2.496 ± 0.045	2.204SerArg: 2.204 ± 0.038	4.294SerSer: 4.294 ± 0.119	3.47SerThr: 3.47 ± 0.079	4.057SerVal: 4.057 ± 0.05	0.67SerTrp: 0.67 ± 0.021	2.502SerTyr: 2.502 ± 0.044	0.0SerXaa: 0.0 ± 0.0
Thr	4.383ThrAla: 4.383 ± 0.071	0.333ThrCys: 0.333 ± 0.014	3.116ThrAsp: 3.116 ± 0.05	3.863ThrGlu: 3.863 ± 0.06	2.618ThrPhe: 2.618 ± 0.045	4.232ThrGly: 4.232 ± 0.06	1.025ThrHis: 1.025 ± 0.024	4.995ThrIle: 4.995 ± 0.065	3.597ThrLys: 3.597 ± 0.055	5.403ThrLeu: 5.403 ± 0.064	1.388ThrMet: 1.388 ± 0.033	2.668ThrAsn: 2.668 ± 0.05	2.516ThrPro: 2.516 ± 0.049	2.26ThrGln: 2.26 ± 0.072	1.922ThrArg: 1.922 ± 0.058	3.515ThrSer: 3.515 ± 0.076	3.549ThrThr: 3.549 ± 0.061	4.466ThrVal: 4.466 ± 0.065	0.506ThrTrp: 0.506 ± 0.019	2.153ThrTyr: 2.153 ± 0.053	0.0ThrXaa: 0.0 ± 0.0
Val	5.079ValAla: 5.079 ± 0.07	0.543ValCys: 0.543 ± 0.021	3.638ValAsp: 3.638 ± 0.056	4.761ValGlu: 4.761 ± 0.057	3.154ValPhe: 3.154 ± 0.052	4.465ValGly: 4.465 ± 0.065	1.046ValHis: 1.046 ± 0.025	5.35ValIle: 5.35 ± 0.078	4.277ValLys: 4.277 ± 0.055	6.671ValLeu: 6.671 ± 0.069	1.782ValMet: 1.782 ± 0.034	3.015ValAsn: 3.015 ± 0.049	2.703ValPro: 2.703 ± 0.044	2.419ValGln: 2.419 ± 0.043	2.318ValArg: 2.318 ± 0.04	4.581ValSer: 4.581 ± 0.057	4.397ValThr: 4.397 ± 0.07	5.031ValVal: 5.031 ± 0.072	0.549ValTrp: 0.549 ± 0.022	2.309ValTyr: 2.309 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	0.506TrpAla: 0.506 ± 0.018	0.078TrpCys: 0.078 ± 0.007	0.461TrpAsp: 0.461 ± 0.02	0.654TrpGlu: 0.654 ± 0.02	0.446TrpPhe: 0.446 ± 0.017	0.702TrpGly: 0.702 ± 0.024	0.18TrpHis: 0.18 ± 0.012	0.65TrpIle: 0.65 ± 0.02	0.561TrpLys: 0.561 ± 0.021	1.157TrpLeu: 1.157 ± 0.03	0.256TrpMet: 0.256 ± 0.012	0.486TrpAsn: 0.486 ± 0.019	0.221TrpPro: 0.221 ± 0.011	0.579TrpGln: 0.579 ± 0.021	0.432TrpArg: 0.432 ± 0.017	0.578TrpSer: 0.578 ± 0.018	0.47TrpThr: 0.47 ± 0.016	0.534TrpVal: 0.534 ± 0.02	0.114TrpTrp: 0.114 ± 0.009	0.363TrpTyr: 0.363 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.28TyrAla: 2.28 ± 0.04	0.327TyrCys: 0.327 ± 0.015	2.168TyrAsp: 2.168 ± 0.053	2.422TyrGlu: 2.422 ± 0.041	2.066TyrPhe: 2.066 ± 0.037	2.435TyrGly: 2.435 ± 0.045	0.863TyrHis: 0.863 ± 0.028	2.085TyrIle: 2.085 ± 0.033	1.779TyrLys: 1.779 ± 0.038	4.177TyrLeu: 4.177 ± 0.065	0.757TyrMet: 0.757 ± 0.022	1.494TyrAsn: 1.494 ± 0.035	1.529TyrPro: 1.529 ± 0.034	2.433TyrGln: 2.433 ± 0.04	1.74TyrArg: 1.74 ± 0.042	2.385TyrSer: 2.385 ± 0.04	1.991TyrThr: 1.991 ± 0.04	2.224TyrVal: 2.224 ± 0.039	0.427TyrTrp: 0.427 ± 0.018	1.716TyrTyr: 1.716 ± 0.033	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5181 proteins (1566595 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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