Amino acid dipepetide frequency for Oryctes rhinoceros nudivirus (isolate Oryctes rhinoceros/Malaysia/Ma07/2007) (OrNV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.644AlaAla: 2.644 ± 0.343
1.709AlaCys: 1.709 ± 0.237
2.964AlaAsp: 2.964 ± 0.245
2.697AlaGlu: 2.697 ± 0.311
2.27AlaPhe: 2.27 ± 0.222
1.683AlaGly: 1.683 ± 0.233
0.855AlaHis: 0.855 ± 0.135
4.166AlaIle: 4.166 ± 0.33
3.418AlaLys: 3.418 ± 0.302
4.567AlaLeu: 4.567 ± 0.34
1.309AlaMet: 1.309 ± 0.213
3.125AlaAsn: 3.125 ± 0.3
1.816AlaPro: 1.816 ± 0.22
1.469AlaGln: 1.469 ± 0.217
2.938AlaArg: 2.938 ± 0.295
4.674AlaSer: 4.674 ± 0.312
3.338AlaThr: 3.338 ± 0.332
3.178AlaVal: 3.178 ± 0.27
0.32AlaTrp: 0.32 ± 0.115
2.697AlaTyr: 2.697 ± 0.251
0.0AlaXaa: 0.0 ± 0.0
Cys
1.335CysAla: 1.335 ± 0.188
0.454CysCys: 0.454 ± 0.123
1.362CysAsp: 1.362 ± 0.234
1.202CysGlu: 1.202 ± 0.189
0.748CysPhe: 0.748 ± 0.14
1.015CysGly: 1.015 ± 0.165
0.507CysHis: 0.507 ± 0.109
1.95CysIle: 1.95 ± 0.267
1.202CysLys: 1.202 ± 0.209
1.442CysLeu: 1.442 ± 0.167
0.855CysMet: 0.855 ± 0.151
1.255CysAsn: 1.255 ± 0.215
0.774CysPro: 0.774 ± 0.139
0.721CysGln: 0.721 ± 0.163
1.202CysArg: 1.202 ± 0.188
2.056CysSer: 2.056 ± 0.282
1.282CysThr: 1.282 ± 0.223
1.709CysVal: 1.709 ± 0.256
0.107CysTrp: 0.107 ± 0.052
0.828CysTyr: 0.828 ± 0.155
0.0CysXaa: 0.0 ± 0.0
Asp
3.766AspAla: 3.766 ± 0.332
1.175AspCys: 1.175 ± 0.182
8.947AspAsp: 8.947 ± 1.011
5.502AspGlu: 5.502 ± 0.504
2.51AspPhe: 2.51 ± 0.234
3.231AspGly: 3.231 ± 0.307
0.908AspHis: 0.908 ± 0.129
4.487AspIle: 4.487 ± 0.379
3.151AspLys: 3.151 ± 0.264
4.273AspLeu: 4.273 ± 0.357
1.683AspMet: 1.683 ± 0.241
2.404AspAsn: 2.404 ± 0.248
2.484AspPro: 2.484 ± 0.233
1.923AspGln: 1.923 ± 0.252
2.537AspArg: 2.537 ± 0.266
4.3AspSer: 4.3 ± 0.395
3.418AspThr: 3.418 ± 0.288
4.407AspVal: 4.407 ± 0.415
0.401AspTrp: 0.401 ± 0.122
2.404AspTyr: 2.404 ± 0.203
0.0AspXaa: 0.0 ± 0.0
Glu
2.751GluAla: 2.751 ± 0.284
1.175GluCys: 1.175 ± 0.162
2.964GluAsp: 2.964 ± 0.275
1.923GluGlu: 1.923 ± 0.233
2.724GluPhe: 2.724 ± 0.273
0.935GluGly: 0.935 ± 0.143
1.282GluHis: 1.282 ± 0.164
3.098GluIle: 3.098 ± 0.338
2.217GluLys: 2.217 ± 0.315
6.062GluLeu: 6.062 ± 0.391
0.988GluMet: 0.988 ± 0.165
3.418GluAsn: 3.418 ± 0.31
2.35GluPro: 2.35 ± 0.299
1.576GluGln: 1.576 ± 0.199
2.564GluArg: 2.564 ± 0.255
5.048GluSer: 5.048 ± 0.291
3.151GluThr: 3.151 ± 0.309
2.35GluVal: 2.35 ± 0.272
0.347GluTrp: 0.347 ± 0.095
3.605GluTyr: 3.605 ± 0.283
0.0GluXaa: 0.0 ± 0.0
Phe
2.377PheAla: 2.377 ± 0.268
0.855PheCys: 0.855 ± 0.168
3.659PheAsp: 3.659 ± 0.31
2.617PheGlu: 2.617 ± 0.285
1.309PhePhe: 1.309 ± 0.212
2.323PheGly: 2.323 ± 0.306
0.721PheHis: 0.721 ± 0.116
3.552PheIle: 3.552 ± 0.269
3.792PheLys: 3.792 ± 0.271
3.445PheLeu: 3.445 ± 0.295
1.522PheMet: 1.522 ± 0.197
2.724PheAsn: 2.724 ± 0.295
1.362PhePro: 1.362 ± 0.177
1.496PheGln: 1.496 ± 0.292
1.896PheArg: 1.896 ± 0.24
3.018PheSer: 3.018 ± 0.306
2.831PheThr: 2.831 ± 0.25
2.51PheVal: 2.51 ± 0.242
0.347PheTrp: 0.347 ± 0.1
2.03PheTyr: 2.03 ± 0.205
0.0PheXaa: 0.0 ± 0.0
Gly
1.496GlyAla: 1.496 ± 0.19
0.961GlyCys: 0.961 ± 0.187
2.323GlyAsp: 2.323 ± 0.32
2.11GlyGlu: 2.11 ± 0.278
2.297GlyPhe: 2.297 ± 0.209
2.27GlyGly: 2.27 ± 0.37
0.641GlyHis: 0.641 ± 0.125
2.751GlyIle: 2.751 ± 0.237
2.217GlyLys: 2.217 ± 0.247
2.884GlyLeu: 2.884 ± 0.355
0.855GlyMet: 0.855 ± 0.162
2.083GlyAsn: 2.083 ± 0.26
0.988GlyPro: 0.988 ± 0.174
1.015GlyGln: 1.015 ± 0.146
1.522GlyArg: 1.522 ± 0.213
2.671GlySer: 2.671 ± 0.266
1.789GlyThr: 1.789 ± 0.289
3.125GlyVal: 3.125 ± 0.295
0.134GlyTrp: 0.134 ± 0.083
2.163GlyTyr: 2.163 ± 0.283
0.0GlyXaa: 0.0 ± 0.0
His
1.095HisAla: 1.095 ± 0.179
0.267HisCys: 0.267 ± 0.072
1.309HisAsp: 1.309 ± 0.192
1.282HisGlu: 1.282 ± 0.188
1.122HisPhe: 1.122 ± 0.207
0.855HisGly: 0.855 ± 0.147
0.401HisHis: 0.401 ± 0.109
2.11HisIle: 2.11 ± 0.262
1.522HisLys: 1.522 ± 0.219
1.923HisLeu: 1.923 ± 0.228
0.427HisMet: 0.427 ± 0.113
1.175HisAsn: 1.175 ± 0.185
1.255HisPro: 1.255 ± 0.182
0.534HisGln: 0.534 ± 0.111
0.935HisArg: 0.935 ± 0.151
1.629HisSer: 1.629 ± 0.239
1.816HisThr: 1.816 ± 0.314
1.255HisVal: 1.255 ± 0.226
0.134HisTrp: 0.134 ± 0.049
0.668HisTyr: 0.668 ± 0.161
0.0HisXaa: 0.0 ± 0.0
Ile
4.086IleAla: 4.086 ± 0.39
1.976IleCys: 1.976 ± 0.209
4.727IleAsp: 4.727 ± 0.396
4.326IleGlu: 4.326 ± 0.347
3.045IlePhe: 3.045 ± 0.28
3.258IleGly: 3.258 ± 0.268
1.816IleHis: 1.816 ± 0.206
6.864IleIle: 6.864 ± 0.371
4.834IleLys: 4.834 ± 0.36
7.585IleLeu: 7.585 ± 0.522
2.03IleMet: 2.03 ± 0.194
5.528IleAsn: 5.528 ± 0.385
3.872IlePro: 3.872 ± 0.281
2.35IleGln: 2.35 ± 0.233
3.979IleArg: 3.979 ± 0.301
6.062IleSer: 6.062 ± 0.371
4.914IleThr: 4.914 ± 0.295
5.395IleVal: 5.395 ± 0.375
0.855IleTrp: 0.855 ± 0.188
3.579IleTyr: 3.579 ± 0.304
0.0IleXaa: 0.0 ± 0.0
Lys
2.724LysAla: 2.724 ± 0.315
1.629LysCys: 1.629 ± 0.231
1.709LysAsp: 1.709 ± 0.2
1.976LysGlu: 1.976 ± 0.229
3.472LysPhe: 3.472 ± 0.283
1.576LysGly: 1.576 ± 0.183
2.297LysHis: 2.297 ± 0.264
5.902LysIle: 5.902 ± 0.412
4.059LysLys: 4.059 ± 0.366
6.543LysLeu: 6.543 ± 0.382
1.709LysMet: 1.709 ± 0.178
4.006LysAsn: 4.006 ± 0.316
2.617LysPro: 2.617 ± 0.279
2.03LysGln: 2.03 ± 0.268
3.979LysArg: 3.979 ± 0.44
5.181LysSer: 5.181 ± 0.342
4.807LysThr: 4.807 ± 0.332
3.712LysVal: 3.712 ± 0.367
0.454LysTrp: 0.454 ± 0.106
3.632LysTyr: 3.632 ± 0.326
0.0LysXaa: 0.0 ± 0.0
Leu
4.834LeuAla: 4.834 ± 0.361
1.976LeuCys: 1.976 ± 0.216
5.448LeuAsp: 5.448 ± 0.39
4.407LeuGlu: 4.407 ± 0.38
3.338LeuPhe: 3.338 ± 0.3
2.457LeuGly: 2.457 ± 0.253
1.976LeuHis: 1.976 ± 0.238
5.715LeuIle: 5.715 ± 0.444
7.291LeuLys: 7.291 ± 0.411
8.76LeuLeu: 8.76 ± 0.56
2.056LeuMet: 2.056 ± 0.238
5.395LeuAsn: 5.395 ± 0.344
3.899LeuPro: 3.899 ± 0.309
2.858LeuGln: 2.858 ± 0.31
3.338LeuArg: 3.338 ± 0.314
6.703LeuSer: 6.703 ± 0.44
5.368LeuThr: 5.368 ± 0.395
4.941LeuVal: 4.941 ± 0.373
1.042LeuTrp: 1.042 ± 0.175
5.048LeuTyr: 5.048 ± 0.371
0.0LeuXaa: 0.0 ± 0.0
Met
1.602MetAla: 1.602 ± 0.226
0.668MetCys: 0.668 ± 0.134
1.789MetAsp: 1.789 ± 0.249
1.015MetGlu: 1.015 ± 0.185
1.309MetPhe: 1.309 ± 0.181
0.881MetGly: 0.881 ± 0.166
0.774MetHis: 0.774 ± 0.134
1.255MetIle: 1.255 ± 0.188
1.415MetLys: 1.415 ± 0.187
2.724MetLeu: 2.724 ± 0.311
0.908MetMet: 0.908 ± 0.139
1.202MetAsn: 1.202 ± 0.18
1.282MetPro: 1.282 ± 0.172
0.748MetGln: 0.748 ± 0.174
1.202MetArg: 1.202 ± 0.193
2.484MetSer: 2.484 ± 0.254
1.362MetThr: 1.362 ± 0.169
1.629MetVal: 1.629 ± 0.179
0.187MetTrp: 0.187 ± 0.068
1.709MetTyr: 1.709 ± 0.24
0.0MetXaa: 0.0 ± 0.0
Asn
4.22AsnAla: 4.22 ± 0.334
1.148AsnCys: 1.148 ± 0.175
3.712AsnAsp: 3.712 ± 0.338
3.071AsnGlu: 3.071 ± 0.238
2.43AsnPhe: 2.43 ± 0.254
2.804AsnGly: 2.804 ± 0.238
1.229AsnHis: 1.229 ± 0.191
5.849AsnIle: 5.849 ± 0.46
3.739AsnLys: 3.739 ± 0.317
5.261AsnLeu: 5.261 ± 0.368
1.683AsnMet: 1.683 ± 0.183
3.766AsnAsn: 3.766 ± 0.324
2.35AsnPro: 2.35 ± 0.244
2.003AsnGln: 2.003 ± 0.217
2.056AsnArg: 2.056 ± 0.23
5.048AsnSer: 5.048 ± 0.391
4.166AsnThr: 4.166 ± 0.324
4.006AsnVal: 4.006 ± 0.371
0.32AsnTrp: 0.32 ± 0.086
2.484AsnTyr: 2.484 ± 0.252
0.0AsnXaa: 0.0 ± 0.0
Pro
1.415ProAla: 1.415 ± 0.176
0.588ProCys: 0.588 ± 0.135
2.323ProAsp: 2.323 ± 0.267
2.297ProGlu: 2.297 ± 0.27
1.602ProPhe: 1.602 ± 0.196
1.282ProGly: 1.282 ± 0.225
0.828ProHis: 0.828 ± 0.151
4.38ProIle: 4.38 ± 0.373
3.953ProLys: 3.953 ± 0.272
3.045ProLeu: 3.045 ± 0.336
0.935ProMet: 0.935 ± 0.135
3.205ProAsn: 3.205 ± 0.284
2.537ProPro: 2.537 ± 0.419
2.404ProGln: 2.404 ± 0.317
1.255ProArg: 1.255 ± 0.206
3.285ProSer: 3.285 ± 0.327
4.22ProThr: 4.22 ± 0.415
1.629ProVal: 1.629 ± 0.199
0.214ProTrp: 0.214 ± 0.068
1.869ProTyr: 1.869 ± 0.221
0.0ProXaa: 0.0 ± 0.0
Gln
1.736GlnAla: 1.736 ± 0.206
0.774GlnCys: 0.774 ± 0.165
1.015GlnAsp: 1.015 ± 0.141
0.961GlnGlu: 0.961 ± 0.183
1.843GlnPhe: 1.843 ± 0.228
0.454GlnGly: 0.454 ± 0.135
0.801GlnHis: 0.801 ± 0.147
2.217GlnIle: 2.217 ± 0.249
1.549GlnLys: 1.549 ± 0.166
3.045GlnLeu: 3.045 ± 0.281
0.855GlnMet: 0.855 ± 0.164
2.911GlnAsn: 2.911 ± 0.27
2.056GlnPro: 2.056 ± 0.278
2.51GlnGln: 2.51 ± 0.459
1.389GlnArg: 1.389 ± 0.182
2.884GlnSer: 2.884 ± 0.324
2.671GlnThr: 2.671 ± 0.319
1.255GlnVal: 1.255 ± 0.223
0.267GlnTrp: 0.267 ± 0.064
2.083GlnTyr: 2.083 ± 0.261
0.0GlnXaa: 0.0 ± 0.0
Arg
2.537ArgAla: 2.537 ± 0.241
0.855ArgCys: 0.855 ± 0.18
2.19ArgAsp: 2.19 ± 0.192
2.003ArgGlu: 2.003 ± 0.238
2.591ArgPhe: 2.591 ± 0.279
1.522ArgGly: 1.522 ± 0.211
0.774ArgHis: 0.774 ± 0.138
3.418ArgIle: 3.418 ± 0.327
3.045ArgLys: 3.045 ± 0.297
3.872ArgLeu: 3.872 ± 0.318
1.736ArgMet: 1.736 ± 0.198
3.018ArgAsn: 3.018 ± 0.313
1.709ArgPro: 1.709 ± 0.211
1.95ArgGln: 1.95 ± 0.22
2.243ArgArg: 2.243 ± 0.249
3.258ArgSer: 3.258 ± 0.421
2.644ArgThr: 2.644 ± 0.231
2.751ArgVal: 2.751 ± 0.28
0.214ArgTrp: 0.214 ± 0.068
2.404ArgTyr: 2.404 ± 0.249
0.0ArgXaa: 0.0 ± 0.0
Ser
4.353SerAla: 4.353 ± 0.294
1.656SerCys: 1.656 ± 0.226
6.276SerAsp: 6.276 ± 0.398
4.273SerGlu: 4.273 ± 0.371
2.724SerPhe: 2.724 ± 0.248
2.911SerGly: 2.911 ± 0.269
1.415SerHis: 1.415 ± 0.181
7.798SerIle: 7.798 ± 0.534
5.555SerLys: 5.555 ± 0.381
5.635SerLeu: 5.635 ± 0.38
2.323SerMet: 2.323 ± 0.252
4.78SerAsn: 4.78 ± 0.396
3.525SerPro: 3.525 ± 0.394
1.869SerGln: 1.869 ± 0.218
3.472SerArg: 3.472 ± 0.39
9.267SerSer: 9.267 ± 0.762
6.81SerThr: 6.81 ± 0.448
4.567SerVal: 4.567 ± 0.341
0.588SerTrp: 0.588 ± 0.137
3.872SerTyr: 3.872 ± 0.359
0.0SerXaa: 0.0 ± 0.0
Thr
2.991ThrAla: 2.991 ± 0.284
1.442ThrCys: 1.442 ± 0.174
3.098ThrAsp: 3.098 ± 0.281
2.911ThrGlu: 2.911 ± 0.294
3.926ThrPhe: 3.926 ± 0.361
2.137ThrGly: 2.137 ± 0.199
2.003ThrHis: 2.003 ± 0.251
6.062ThrIle: 6.062 ± 0.438
3.766ThrLys: 3.766 ± 0.343
6.383ThrLeu: 6.383 ± 0.385
1.415ThrMet: 1.415 ± 0.18
3.979ThrAsn: 3.979 ± 0.263
3.739ThrPro: 3.739 ± 0.374
2.35ThrGln: 2.35 ± 0.322
2.858ThrArg: 2.858 ± 0.277
6.116ThrSer: 6.116 ± 0.509
6.57ThrThr: 6.57 ± 0.778
3.392ThrVal: 3.392 ± 0.309
0.267ThrTrp: 0.267 ± 0.077
3.018ThrTyr: 3.018 ± 0.274
0.0ThrXaa: 0.0 ± 0.0
Val
2.964ValAla: 2.964 ± 0.266
1.629ValCys: 1.629 ± 0.271
4.166ValAsp: 4.166 ± 0.393
3.151ValGlu: 3.151 ± 0.323
2.591ValPhe: 2.591 ± 0.259
2.404ValGly: 2.404 ± 0.237
1.469ValHis: 1.469 ± 0.211
4.54ValIle: 4.54 ± 0.41
3.365ValLys: 3.365 ± 0.292
5.154ValLeu: 5.154 ± 0.401
1.362ValMet: 1.362 ± 0.188
3.285ValAsn: 3.285 ± 0.262
2.377ValPro: 2.377 ± 0.268
1.736ValGln: 1.736 ± 0.236
3.018ValArg: 3.018 ± 0.314
5.448ValSer: 5.448 ± 0.393
3.125ValThr: 3.125 ± 0.304
3.979ValVal: 3.979 ± 0.305
0.507ValTrp: 0.507 ± 0.12
3.312ValTyr: 3.312 ± 0.317
0.0ValXaa: 0.0 ± 0.0
Trp
0.294TrpAla: 0.294 ± 0.093
0.267TrpCys: 0.267 ± 0.08
0.374TrpAsp: 0.374 ± 0.096
0.32TrpGlu: 0.32 ± 0.1
0.588TrpPhe: 0.588 ± 0.139
0.24TrpGly: 0.24 ± 0.08
0.267TrpHis: 0.267 ± 0.087
0.374TrpIle: 0.374 ± 0.094
0.454TrpLys: 0.454 ± 0.115
0.721TrpLeu: 0.721 ± 0.149
0.16TrpMet: 0.16 ± 0.066
0.294TrpAsn: 0.294 ± 0.092
0.347TrpPro: 0.347 ± 0.104
0.134TrpGln: 0.134 ± 0.064
0.374TrpArg: 0.374 ± 0.097
0.748TrpSer: 0.748 ± 0.148
0.347TrpThr: 0.347 ± 0.093
0.374TrpVal: 0.374 ± 0.1
0.053TrpTrp: 0.053 ± 0.043
0.347TrpTyr: 0.347 ± 0.097
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.644TyrAla: 2.644 ± 0.277
0.801TyrCys: 0.801 ± 0.126
3.552TyrAsp: 3.552 ± 0.306
2.484TyrGlu: 2.484 ± 0.216
1.95TyrPhe: 1.95 ± 0.243
2.056TyrGly: 2.056 ± 0.241
0.748TyrHis: 0.748 ± 0.137
4.594TyrIle: 4.594 ± 0.349
3.472TyrLys: 3.472 ± 0.335
3.525TyrLeu: 3.525 ± 0.323
1.309TyrMet: 1.309 ± 0.193
3.792TyrAsn: 3.792 ± 0.317
1.923TyrPro: 1.923 ± 0.258
1.602TyrGln: 1.602 ± 0.203
1.976TyrArg: 1.976 ± 0.237
3.792TyrSer: 3.792 ± 0.335
3.792TyrThr: 3.792 ± 0.332
3.418TyrVal: 3.418 ± 0.366
0.32TyrTrp: 0.32 ± 0.109
2.11TyrTyr: 2.11 ± 0.215
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 138 proteins (37445 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski