Amino acid dipepetide frequency for Pseudorhizobium banfieldiae

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	15.873AlaAla: 15.873 ± 0.154	0.997AlaCys: 0.997 ± 0.028	6.442AlaAsp: 6.442 ± 0.082	7.822AlaGlu: 7.822 ± 0.092	4.454AlaPhe: 4.454 ± 0.058	10.093AlaGly: 10.093 ± 0.102	2.067AlaHis: 2.067 ± 0.04	6.574AlaIle: 6.574 ± 0.074	3.842AlaLys: 3.842 ± 0.053	12.35AlaLeu: 12.35 ± 0.102	3.584AlaMet: 3.584 ± 0.054	2.793AlaAsn: 2.793 ± 0.043	4.854AlaPro: 4.854 ± 0.081	3.566AlaGln: 3.566 ± 0.059	7.784AlaArg: 7.784 ± 0.087	6.574AlaSer: 6.574 ± 0.073	5.805AlaThr: 5.805 ± 0.07	8.647AlaVal: 8.647 ± 0.084	1.352AlaTrp: 1.352 ± 0.036	2.471AlaTyr: 2.471 ± 0.037	0.0AlaXaa: 0.0 ± 0.0
Cys	0.851CysAla: 0.851 ± 0.028	0.129CysCys: 0.129 ± 0.011	0.494CysAsp: 0.494 ± 0.02	0.454CysGlu: 0.454 ± 0.016	0.317CysPhe: 0.317 ± 0.016	0.952CysGly: 0.952 ± 0.029	0.255CysHis: 0.255 ± 0.015	0.413CysIle: 0.413 ± 0.016	0.19CysLys: 0.19 ± 0.011	0.826CysLeu: 0.826 ± 0.025	0.182CysMet: 0.182 ± 0.012	0.194CysAsn: 0.194 ± 0.013	0.409CysPro: 0.409 ± 0.018	0.25CysGln: 0.25 ± 0.014	0.683CysArg: 0.683 ± 0.025	0.468CysSer: 0.468 ± 0.017	0.407CysThr: 0.407 ± 0.019	0.592CysVal: 0.592 ± 0.021	0.114CysTrp: 0.114 ± 0.01	0.186CysTyr: 0.186 ± 0.011	0.0CysXaa: 0.0 ± 0.0
Asp	6.348AspAla: 6.348 ± 0.083	0.506AspCys: 0.506 ± 0.018	3.093AspAsp: 3.093 ± 0.05	3.661AspGlu: 3.661 ± 0.051	2.206AspPhe: 2.206 ± 0.046	4.923AspGly: 4.923 ± 0.078	1.274AspHis: 1.274 ± 0.035	3.226AspIle: 3.226 ± 0.046	1.68AspLys: 1.68 ± 0.042	6.025AspLeu: 6.025 ± 0.071	1.423AspMet: 1.423 ± 0.03	1.305AspAsn: 1.305 ± 0.034	3.234AspPro: 3.234 ± 0.052	1.751AspGln: 1.751 ± 0.04	4.384AspArg: 4.384 ± 0.06	2.015AspSer: 2.015 ± 0.035	2.483AspThr: 2.483 ± 0.044	4.216AspVal: 4.216 ± 0.06	0.96AspTrp: 0.96 ± 0.029	1.504AspTyr: 1.504 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	7.952GluAla: 7.952 ± 0.094	0.367GluCys: 0.367 ± 0.018	3.132GluAsp: 3.132 ± 0.055	4.168GluGlu: 4.168 ± 0.076	1.904GluPhe: 1.904 ± 0.036	4.803GluGly: 4.803 ± 0.059	1.247GluHis: 1.247 ± 0.029	3.772GluIle: 3.772 ± 0.056	2.689GluLys: 2.689 ± 0.051	5.569GluLeu: 5.569 ± 0.07	1.681GluMet: 1.681 ± 0.037	1.858GluAsn: 1.858 ± 0.038	2.852GluPro: 2.852 ± 0.05	2.321GluGln: 2.321 ± 0.047	5.177GluArg: 5.177 ± 0.078	2.402GluSer: 2.402 ± 0.044	3.632GluThr: 3.632 ± 0.057	4.246GluVal: 4.246 ± 0.057	0.771GluTrp: 0.771 ± 0.027	1.08GluTyr: 1.08 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	4.379PheAla: 4.379 ± 0.058	0.375PheCys: 0.375 ± 0.017	2.612PheAsp: 2.612 ± 0.046	2.179PheGlu: 2.179 ± 0.041	1.542PhePhe: 1.542 ± 0.039	3.65PheGly: 3.65 ± 0.056	0.81PheHis: 0.81 ± 0.027	1.862PheIle: 1.862 ± 0.043	1.023PheLys: 1.023 ± 0.029	3.641PheLeu: 3.641 ± 0.062	0.88PheMet: 0.88 ± 0.025	1.098PheAsn: 1.098 ± 0.028	1.684PhePro: 1.684 ± 0.038	1.099PheGln: 1.099 ± 0.029	2.41PheArg: 2.41 ± 0.042	2.441PheSer: 2.441 ± 0.046	1.946PheThr: 1.946 ± 0.04	2.854PheVal: 2.854 ± 0.051	0.514PheTrp: 0.514 ± 0.023	0.925PheTyr: 0.925 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	8.382GlyAla: 8.382 ± 0.093	0.826GlyCys: 0.826 ± 0.026	4.332GlyAsp: 4.332 ± 0.069	5.161GlyGlu: 5.161 ± 0.078	3.626GlyPhe: 3.626 ± 0.047	7.077GlyGly: 7.077 ± 0.105	1.903GlyHis: 1.903 ± 0.046	4.948GlyIle: 4.948 ± 0.075	3.309GlyLys: 3.309 ± 0.057	8.708GlyLeu: 8.708 ± 0.093	2.428GlyMet: 2.428 ± 0.048	2.238GlyAsn: 2.238 ± 0.049	3.242GlyPro: 3.242 ± 0.046	2.734GlyGln: 2.734 ± 0.051	6.084GlyArg: 6.084 ± 0.069	4.942GlySer: 4.942 ± 0.064	4.461GlyThr: 4.461 ± 0.06	5.889GlyVal: 5.889 ± 0.07	1.231GlyTrp: 1.231 ± 0.029	2.369GlyTyr: 2.369 ± 0.039	0.0GlyXaa: 0.0 ± 0.0
His	2.147HisAla: 2.147 ± 0.04	0.231HisCys: 0.231 ± 0.013	1.225HisAsp: 1.225 ± 0.032	1.132HisGlu: 1.132 ± 0.03	0.824HisPhe: 0.824 ± 0.024	1.942HisGly: 1.942 ± 0.043	0.619HisHis: 0.619 ± 0.026	0.966HisIle: 0.966 ± 0.027	0.474HisLys: 0.474 ± 0.018	2.144HisLeu: 2.144 ± 0.041	0.54HisMet: 0.54 ± 0.022	0.468HisAsn: 0.468 ± 0.02	1.331HisPro: 1.331 ± 0.036	0.622HisGln: 0.622 ± 0.018	1.478HisArg: 1.478 ± 0.035	1.062HisSer: 1.062 ± 0.029	0.822HisThr: 0.822 ± 0.024	1.611HisVal: 1.611 ± 0.032	0.283HisTrp: 0.283 ± 0.015	0.546HisTyr: 0.546 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	7.188IleAla: 7.188 ± 0.074	0.559IleCys: 0.559 ± 0.022	3.646IleAsp: 3.646 ± 0.057	3.615IleGlu: 3.615 ± 0.055	2.008IlePhe: 2.008 ± 0.044	5.161IleGly: 5.161 ± 0.072	1.0IleHis: 1.0 ± 0.026	2.696IleIle: 2.696 ± 0.046	1.456IleLys: 1.456 ± 0.032	5.083IleLeu: 5.083 ± 0.066	1.129IleMet: 1.129 ± 0.032	1.564IleAsn: 1.564 ± 0.033	2.486IlePro: 2.486 ± 0.047	1.273IleGln: 1.273 ± 0.032	3.709IleArg: 3.709 ± 0.049	3.266IleSer: 3.266 ± 0.045	2.7IleThr: 2.7 ± 0.048	4.339IleVal: 4.339 ± 0.066	0.626IleTrp: 0.626 ± 0.022	1.275IleTyr: 1.275 ± 0.029	0.0IleXaa: 0.0 ± 0.0
Lys	4.298LysAla: 4.298 ± 0.069	0.188LysCys: 0.188 ± 0.013	1.813LysAsp: 1.813 ± 0.045	1.873LysGlu: 1.873 ± 0.042	0.864LysPhe: 0.864 ± 0.025	2.677LysGly: 2.677 ± 0.041	0.648LysHis: 0.648 ± 0.023	1.836LysIle: 1.836 ± 0.043	1.409LysLys: 1.409 ± 0.034	3.346LysLeu: 3.346 ± 0.054	0.839LysMet: 0.839 ± 0.025	0.971LysAsn: 0.971 ± 0.03	2.061LysPro: 2.061 ± 0.042	1.033LysGln: 1.033 ± 0.025	2.47LysArg: 2.47 ± 0.046	1.856LysSer: 1.856 ± 0.038	2.062LysThr: 2.062 ± 0.038	2.534LysVal: 2.534 ± 0.053	0.37LysTrp: 0.37 ± 0.017	0.602LysTyr: 0.602 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	12.93LeuAla: 12.93 ± 0.117	0.853LeuCys: 0.853 ± 0.025	5.907LeuAsp: 5.907 ± 0.066	5.67LeuGlu: 5.67 ± 0.068	3.716LeuPhe: 3.716 ± 0.061	7.984LeuGly: 7.984 ± 0.083	1.875LeuHis: 1.875 ± 0.039	5.149LeuIle: 5.149 ± 0.073	3.746LeuLys: 3.746 ± 0.054	9.897LeuLeu: 9.897 ± 0.117	2.484LeuMet: 2.484 ± 0.046	2.541LeuAsn: 2.541 ± 0.046	5.412LeuPro: 5.412 ± 0.069	3.018LeuGln: 3.018 ± 0.049	6.682LeuArg: 6.682 ± 0.079	6.815LeuSer: 6.815 ± 0.074	5.511LeuThr: 5.511 ± 0.077	7.513LeuVal: 7.513 ± 0.083	1.126LeuTrp: 1.126 ± 0.032	2.002LeuTyr: 2.002 ± 0.035	0.0LeuXaa: 0.0 ± 0.0
Met	3.229MetAla: 3.229 ± 0.05	0.153MetCys: 0.153 ± 0.011	1.225MetAsp: 1.225 ± 0.028	1.427MetGlu: 1.427 ± 0.033	0.802MetPhe: 0.802 ± 0.021	1.954MetGly: 1.954 ± 0.045	0.436MetHis: 0.436 ± 0.019	1.565MetIle: 1.565 ± 0.036	1.151MetLys: 1.151 ± 0.03	2.654MetLeu: 2.654 ± 0.047	0.788MetMet: 0.788 ± 0.025	0.869MetAsn: 0.869 ± 0.021	1.528MetPro: 1.528 ± 0.035	0.869MetGln: 0.869 ± 0.024	1.864MetArg: 1.864 ± 0.036	1.77MetSer: 1.77 ± 0.036	1.958MetThr: 1.958 ± 0.035	1.857MetVal: 1.857 ± 0.038	0.198MetTrp: 0.198 ± 0.011	0.33MetTyr: 0.33 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	3.044AsnAla: 3.044 ± 0.056	0.244AsnCys: 0.244 ± 0.015	1.381AsnAsp: 1.381 ± 0.034	1.397AsnGlu: 1.397 ± 0.036	0.974AsnPhe: 0.974 ± 0.032	2.506AsnGly: 2.506 ± 0.05	0.568AsnHis: 0.568 ± 0.02	1.444AsnIle: 1.444 ± 0.032	0.714AsnLys: 0.714 ± 0.02	2.687AsnLeu: 2.687 ± 0.047	0.699AsnMet: 0.699 ± 0.023	0.733AsnAsn: 0.733 ± 0.027	1.826AsnPro: 1.826 ± 0.037	0.798AsnGln: 0.798 ± 0.027	1.977AsnArg: 1.977 ± 0.042	1.336AsnSer: 1.336 ± 0.029	1.272AsnThr: 1.272 ± 0.032	1.921AsnVal: 1.921 ± 0.038	0.434AsnTrp: 0.434 ± 0.018	0.66AsnTyr: 0.66 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	5.71ProAla: 5.71 ± 0.079	0.324ProCys: 0.324 ± 0.015	3.356ProAsp: 3.356 ± 0.05	3.862ProGlu: 3.862 ± 0.062	1.958ProPhe: 1.958 ± 0.038	4.124ProGly: 4.124 ± 0.051	1.042ProHis: 1.042 ± 0.03	2.339ProIle: 2.339 ± 0.041	1.671ProLys: 1.671 ± 0.035	4.625ProLeu: 4.625 ± 0.071	1.261ProMet: 1.261 ± 0.03	1.293ProAsn: 1.293 ± 0.032	2.393ProPro: 2.393 ± 0.051	1.736ProGln: 1.736 ± 0.036	2.788ProArg: 2.788 ± 0.05	2.852ProSer: 2.852 ± 0.044	2.404ProThr: 2.404 ± 0.045	4.219ProVal: 4.219 ± 0.066	0.605ProTrp: 0.605 ± 0.021	1.186ProTyr: 1.186 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	3.962GlnAla: 3.962 ± 0.06	0.199GlnCys: 0.199 ± 0.014	1.546GlnAsp: 1.546 ± 0.035	1.918GlnGlu: 1.918 ± 0.039	1.079GlnPhe: 1.079 ± 0.03	2.36GlnGly: 2.36 ± 0.041	0.646GlnHis: 0.646 ± 0.019	1.817GlnIle: 1.817 ± 0.035	1.183GlnLys: 1.183 ± 0.029	2.849GlnLeu: 2.849 ± 0.052	0.997GlnMet: 0.997 ± 0.029	0.869GlnAsn: 0.869 ± 0.027	1.769GlnPro: 1.769 ± 0.041	1.308GlnGln: 1.308 ± 0.041	2.353GlnArg: 2.353 ± 0.051	1.793GlnSer: 1.793 ± 0.038	1.74GlnThr: 1.74 ± 0.035	2.316GlnVal: 2.316 ± 0.045	0.359GlnTrp: 0.359 ± 0.014	0.584GlnTyr: 0.584 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	6.976ArgAla: 6.976 ± 0.085	0.496ArgCys: 0.496 ± 0.019	3.978ArgAsp: 3.978 ± 0.061	4.397ArgGlu: 4.397 ± 0.063	2.919ArgPhe: 2.919 ± 0.045	4.56ArgGly: 4.56 ± 0.063	1.736ArgHis: 1.736 ± 0.035	4.201ArgIle: 4.201 ± 0.058	2.503ArgLys: 2.503 ± 0.044	7.798ArgLeu: 7.798 ± 0.092	2.054ArgMet: 2.054 ± 0.038	2.082ArgAsn: 2.082 ± 0.042	3.449ArgPro: 3.449 ± 0.045	2.828ArgGln: 2.828 ± 0.05	5.867ArgArg: 5.867 ± 0.089	4.25ArgSer: 4.25 ± 0.068	3.371ArgThr: 3.371 ± 0.047	4.485ArgVal: 4.485 ± 0.065	0.915ArgTrp: 0.915 ± 0.029	1.813ArgTyr: 1.813 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	6.253SerAla: 6.253 ± 0.072	0.456SerCys: 0.456 ± 0.02	3.116SerAsp: 3.116 ± 0.052	3.259SerGlu: 3.259 ± 0.051	2.47SerPhe: 2.47 ± 0.037	5.696SerGly: 5.696 ± 0.065	1.135SerHis: 1.135 ± 0.03	3.087SerIle: 3.087 ± 0.054	1.675SerLys: 1.675 ± 0.039	5.771SerLeu: 5.771 ± 0.071	1.496SerMet: 1.496 ± 0.034	1.372SerAsn: 1.372 ± 0.034	2.846SerPro: 2.846 ± 0.051	1.748SerGln: 1.748 ± 0.04	4.016SerArg: 4.016 ± 0.052	3.394SerSer: 3.394 ± 0.052	2.854SerThr: 2.854 ± 0.043	4.178SerVal: 4.178 ± 0.054	0.715SerTrp: 0.715 ± 0.028	1.415SerTyr: 1.415 ± 0.034	0.0SerXaa: 0.0 ± 0.0
Thr	6.013ThrAla: 6.013 ± 0.068	0.467ThrCys: 0.467 ± 0.02	2.826ThrAsp: 2.826 ± 0.047	2.892ThrGlu: 2.892 ± 0.049	1.968ThrPhe: 1.968 ± 0.041	5.011ThrGly: 5.011 ± 0.065	1.032ThrHis: 1.032 ± 0.023	3.135ThrIle: 3.135 ± 0.045	1.506ThrLys: 1.506 ± 0.03	5.433ThrLeu: 5.433 ± 0.069	1.346ThrMet: 1.346 ± 0.035	1.346ThrAsn: 1.346 ± 0.033	2.908ThrPro: 2.908 ± 0.049	1.394ThrGln: 1.394 ± 0.031	3.212ThrArg: 3.212 ± 0.058	3.069ThrSer: 3.069 ± 0.052	2.767ThrThr: 2.767 ± 0.054	4.318ThrVal: 4.318 ± 0.06	0.645ThrTrp: 0.645 ± 0.023	1.241ThrTyr: 1.241 ± 0.029	0.0ThrXaa: 0.0 ± 0.0
Val	8.9ValAla: 8.9 ± 0.092	0.618ValCys: 0.618 ± 0.024	4.05ValAsp: 4.05 ± 0.051	4.867ValGlu: 4.867 ± 0.065	2.799ValPhe: 2.799 ± 0.047	5.505ValGly: 5.505 ± 0.064	1.401ValHis: 1.401 ± 0.034	4.12ValIle: 4.12 ± 0.057	2.385ValLys: 2.385 ± 0.044	7.421ValLeu: 7.421 ± 0.087	1.958ValMet: 1.958 ± 0.044	2.013ValAsn: 2.013 ± 0.035	3.698ValPro: 3.698 ± 0.055	2.008ValGln: 2.008 ± 0.038	4.867ValArg: 4.867 ± 0.06	4.6ValSer: 4.6 ± 0.053	4.567ValThr: 4.567 ± 0.052	5.916ValVal: 5.916 ± 0.077	0.876ValTrp: 0.876 ± 0.028	1.538ValTyr: 1.538 ± 0.035	0.0ValXaa: 0.0 ± 0.0
Trp	1.122TrpAla: 1.122 ± 0.029	0.137TrpCys: 0.137 ± 0.009	0.597TrpAsp: 0.597 ± 0.021	0.582TrpGlu: 0.582 ± 0.022	0.548TrpPhe: 0.548 ± 0.02	0.794TrpGly: 0.794 ± 0.024	0.29TrpHis: 0.29 ± 0.014	0.692TrpIle: 0.692 ± 0.024	0.499TrpLys: 0.499 ± 0.021	1.597TrpLeu: 1.597 ± 0.036	0.378TrpMet: 0.378 ± 0.019	0.421TrpAsn: 0.421 ± 0.018	0.619TrpPro: 0.619 ± 0.023	0.561TrpGln: 0.561 ± 0.02	1.05TrpArg: 1.05 ± 0.027	0.837TrpSer: 0.837 ± 0.025	0.699TrpThr: 0.699 ± 0.023	0.743TrpVal: 0.743 ± 0.027	0.217TrpTrp: 0.217 ± 0.013	0.282TrpTyr: 0.282 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.385TyrAla: 2.385 ± 0.043	0.238TyrCys: 0.238 ± 0.013	1.445TyrAsp: 1.445 ± 0.036	1.286TyrGlu: 1.286 ± 0.033	0.944TyrPhe: 0.944 ± 0.029	2.12TyrGly: 2.12 ± 0.041	0.482TyrHis: 0.482 ± 0.019	0.941TyrIle: 0.941 ± 0.027	0.647TyrLys: 0.647 ± 0.024	2.406TyrLeu: 2.406 ± 0.047	0.479TyrMet: 0.479 ± 0.017	0.59TyrAsn: 0.59 ± 0.024	1.149TyrPro: 1.149 ± 0.03	0.73TyrGln: 0.73 ± 0.024	1.819TyrArg: 1.819 ± 0.041	1.208TyrSer: 1.208 ± 0.031	1.068TyrThr: 1.068 ± 0.029	1.712TyrVal: 1.712 ± 0.034	0.356TyrTrp: 0.356 ± 0.016	0.634TyrTyr: 0.634 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4603 proteins (1374660 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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