Amino acid dipepetide frequency for Cleome leaf crumple virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.298AlaAla: 3.298 ± 1.461
0.66AlaCys: 0.66 ± 0.558
2.639AlaAsp: 2.639 ± 0.65
1.979AlaGlu: 1.979 ± 1.18
1.319AlaPhe: 1.319 ± 0.756
0.66AlaGly: 0.66 ± 0.466
1.979AlaHis: 1.979 ± 0.949
1.979AlaIle: 1.979 ± 0.844
4.617AlaLys: 4.617 ± 1.259
6.596AlaLeu: 6.596 ± 2.699
0.66AlaMet: 0.66 ± 0.466
3.298AlaAsn: 3.298 ± 0.826
5.937AlaPro: 5.937 ± 0.927
2.639AlaGln: 2.639 ± 1.182
5.937AlaArg: 5.937 ± 2.684
6.596AlaSer: 6.596 ± 2.131
3.958AlaThr: 3.958 ± 1.202
3.298AlaVal: 3.298 ± 1.67
0.66AlaTrp: 0.66 ± 0.558
0.66AlaTyr: 0.66 ± 0.522
0.0AlaXaa: 0.0 ± 0.0
Cys
1.319CysAla: 1.319 ± 1.108
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.66CysGlu: 0.66 ± 0.558
0.66CysPhe: 0.66 ± 0.663
0.66CysGly: 0.66 ± 0.554
0.66CysHis: 0.66 ± 0.585
1.319CysIle: 1.319 ± 0.662
1.319CysLys: 1.319 ± 0.654
0.66CysLeu: 0.66 ± 0.466
0.66CysMet: 0.66 ± 0.585
1.979CysAsn: 1.979 ± 0.489
0.0CysPro: 0.0 ± 0.0
1.319CysGln: 1.319 ± 1.043
1.319CysArg: 1.319 ± 0.838
0.66CysSer: 0.66 ± 0.522
1.319CysThr: 1.319 ± 0.738
2.639CysVal: 2.639 ± 1.372
1.319CysTrp: 1.319 ± 0.932
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
3.958AspAla: 3.958 ± 1.242
0.0AspCys: 0.0 ± 0.0
0.66AspAsp: 0.66 ± 0.522
4.617AspGlu: 4.617 ± 0.727
2.639AspPhe: 2.639 ± 1.413
1.979AspGly: 1.979 ± 0.946
0.66AspHis: 0.66 ± 0.585
4.617AspIle: 4.617 ± 1.765
2.639AspLys: 2.639 ± 1.182
6.596AspLeu: 6.596 ± 1.407
0.0AspMet: 0.0 ± 0.0
2.639AspAsn: 2.639 ± 0.651
2.639AspPro: 2.639 ± 1.257
0.66AspGln: 0.66 ± 0.466
3.298AspArg: 3.298 ± 1.083
7.256AspSer: 7.256 ± 1.454
1.319AspThr: 1.319 ± 1.043
2.639AspVal: 2.639 ± 0.941
0.66AspTrp: 0.66 ± 0.522
0.66AspTyr: 0.66 ± 0.466
0.0AspXaa: 0.0 ± 0.0
Glu
2.639GluAla: 2.639 ± 1.083
0.66GluCys: 0.66 ± 0.585
0.66GluAsp: 0.66 ± 0.466
2.639GluGlu: 2.639 ± 1.575
1.319GluPhe: 1.319 ± 0.722
5.277GluGly: 5.277 ± 1.533
0.66GluHis: 0.66 ± 0.663
2.639GluIle: 2.639 ± 1.513
1.319GluLys: 1.319 ± 0.533
3.958GluLeu: 3.958 ± 1.011
1.319GluMet: 1.319 ± 0.591
3.958GluAsn: 3.958 ± 1.741
1.979GluPro: 1.979 ± 1.043
1.979GluGln: 1.979 ± 1.098
2.639GluArg: 2.639 ± 1.39
5.937GluSer: 5.937 ± 2.622
0.66GluThr: 0.66 ± 0.522
1.319GluVal: 1.319 ± 0.779
1.319GluTrp: 1.319 ± 0.698
1.979GluTyr: 1.979 ± 1.054
0.0GluXaa: 0.0 ± 0.0
Phe
2.639PheAla: 2.639 ± 1.035
1.319PheCys: 1.319 ± 0.686
1.979PheAsp: 1.979 ± 0.657
0.66PheGlu: 0.66 ± 0.522
1.319PhePhe: 1.319 ± 0.591
2.639PheGly: 2.639 ± 1.04
1.319PheHis: 1.319 ± 0.654
1.319PheIle: 1.319 ± 0.533
4.617PheLys: 4.617 ± 1.721
3.298PheLeu: 3.298 ± 2.144
0.66PheMet: 0.66 ± 0.573
2.639PheAsn: 2.639 ± 0.601
2.639PhePro: 2.639 ± 0.938
2.639PheGln: 2.639 ± 0.838
1.319PheArg: 1.319 ± 0.662
3.298PheSer: 3.298 ± 1.469
1.979PheThr: 1.979 ± 0.726
2.639PheVal: 2.639 ± 1.065
1.319PheTrp: 1.319 ± 0.738
1.319PheTyr: 1.319 ± 0.722
0.0PheXaa: 0.0 ± 0.0
Gly
3.958GlyAla: 3.958 ± 0.979
2.639GlyCys: 2.639 ± 0.76
3.958GlyAsp: 3.958 ± 1.768
5.937GlyGlu: 5.937 ± 1.719
0.66GlyPhe: 0.66 ± 0.554
3.298GlyGly: 3.298 ± 1.298
1.319GlyHis: 1.319 ± 0.533
1.979GlyIle: 1.979 ± 0.787
5.937GlyLys: 5.937 ± 1.364
1.979GlyLeu: 1.979 ± 0.844
0.66GlyMet: 0.66 ± 0.397
1.979GlyAsn: 1.979 ± 1.08
2.639GlyPro: 2.639 ± 0.452
2.639GlyGln: 2.639 ± 1.238
1.979GlyArg: 1.979 ± 0.854
3.958GlySer: 3.958 ± 1.434
4.617GlyThr: 4.617 ± 1.401
3.298GlyVal: 3.298 ± 1.549
0.0GlyTrp: 0.0 ± 0.0
0.66GlyTyr: 0.66 ± 0.585
0.0GlyXaa: 0.0 ± 0.0
His
1.319HisAla: 1.319 ± 0.722
1.979HisCys: 1.979 ± 0.925
2.639HisAsp: 2.639 ± 0.948
0.66HisGlu: 0.66 ± 0.466
1.319HisPhe: 1.319 ± 0.591
0.66HisGly: 0.66 ± 0.466
0.66HisHis: 0.66 ± 0.554
1.319HisIle: 1.319 ± 0.838
0.66HisLys: 0.66 ± 0.601
4.617HisLeu: 4.617 ± 1.241
0.0HisMet: 0.0 ± 0.0
2.639HisAsn: 2.639 ± 1.076
1.319HisPro: 1.319 ± 0.591
1.319HisGln: 1.319 ± 0.686
2.639HisArg: 2.639 ± 1.214
3.958HisSer: 3.958 ± 1.121
2.639HisThr: 2.639 ± 1.284
4.617HisVal: 4.617 ± 1.38
0.66HisTrp: 0.66 ± 0.522
1.319HisTyr: 1.319 ± 0.591
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.0IleCys: 0.0 ± 0.0
4.617IleAsp: 4.617 ± 2.102
3.958IleGlu: 3.958 ± 1.986
0.66IlePhe: 0.66 ± 0.522
0.66IleGly: 0.66 ± 0.554
2.639IleHis: 2.639 ± 1.117
0.0IleIle: 0.0 ± 0.0
3.958IleLys: 3.958 ± 0.97
5.277IleLeu: 5.277 ± 0.914
0.0IleMet: 0.0 ± 0.0
1.979IleAsn: 1.979 ± 1.054
1.979IlePro: 1.979 ± 1.054
0.66IleGln: 0.66 ± 0.601
5.277IleArg: 5.277 ± 1.55
5.277IleSer: 5.277 ± 1.41
3.958IleThr: 3.958 ± 1.329
3.298IleVal: 3.298 ± 1.606
0.0IleTrp: 0.0 ± 0.0
2.639IleTyr: 2.639 ± 1.186
0.0IleXaa: 0.0 ± 0.0
Lys
2.639LysAla: 2.639 ± 1.262
1.319LysCys: 1.319 ± 1.043
3.958LysAsp: 3.958 ± 1.054
2.639LysGlu: 2.639 ± 1.432
2.639LysPhe: 2.639 ± 0.765
1.979LysGly: 1.979 ± 0.489
2.639LysHis: 2.639 ± 0.956
4.617LysIle: 4.617 ± 0.829
0.66LysLys: 0.66 ± 0.522
5.277LysLeu: 5.277 ± 1.799
0.66LysMet: 0.66 ± 0.522
1.979LysAsn: 1.979 ± 1.204
1.979LysPro: 1.979 ± 0.567
0.66LysGln: 0.66 ± 0.585
6.596LysArg: 6.596 ± 2.166
3.958LysSer: 3.958 ± 0.97
1.979LysThr: 1.979 ± 0.788
5.937LysVal: 5.937 ± 2.748
0.66LysTrp: 0.66 ± 0.585
1.979LysTyr: 1.979 ± 0.657
0.0LysXaa: 0.0 ± 0.0
Leu
1.319LeuAla: 1.319 ± 0.591
0.66LeuCys: 0.66 ± 0.522
4.617LeuAsp: 4.617 ± 0.989
3.298LeuGlu: 3.298 ± 1.49
1.979LeuPhe: 1.979 ± 0.872
3.298LeuGly: 3.298 ± 0.813
5.277LeuHis: 5.277 ± 1.642
2.639LeuIle: 2.639 ± 1.309
6.596LeuLys: 6.596 ± 1.444
2.639LeuLeu: 2.639 ± 1.097
1.319LeuMet: 1.319 ± 0.735
6.596LeuAsn: 6.596 ± 2.266
1.979LeuPro: 1.979 ± 1.663
4.617LeuGln: 4.617 ± 1.755
4.617LeuArg: 4.617 ± 0.652
9.894LeuSer: 9.894 ± 2.022
3.958LeuThr: 3.958 ± 1.577
5.937LeuVal: 5.937 ± 1.096
1.319LeuTrp: 1.319 ± 0.78
3.298LeuTyr: 3.298 ± 1.06
0.0LeuXaa: 0.0 ± 0.0
Met
0.66MetAla: 0.66 ± 0.558
0.66MetCys: 0.66 ± 0.558
1.979MetAsp: 1.979 ± 0.827
1.319MetGlu: 1.319 ± 0.686
0.0MetPhe: 0.0 ± 0.0
1.979MetGly: 1.979 ± 0.939
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.66MetLys: 0.66 ± 0.585
0.66MetLeu: 0.66 ± 0.558
0.0MetMet: 0.0 ± 0.0
0.0MetAsn: 0.0 ± 0.0
1.319MetPro: 1.319 ± 0.654
1.319MetGln: 1.319 ± 0.533
1.319MetArg: 1.319 ± 0.782
1.319MetSer: 1.319 ± 0.932
1.319MetThr: 1.319 ± 1.17
0.66MetVal: 0.66 ± 0.466
0.66MetTrp: 0.66 ± 0.522
3.298MetTyr: 3.298 ± 1.686
0.0MetXaa: 0.0 ± 0.0
Asn
5.937AsnAla: 5.937 ± 0.951
2.639AsnCys: 2.639 ± 1.149
2.639AsnAsp: 2.639 ± 0.651
2.639AsnGlu: 2.639 ± 0.957
1.319AsnPhe: 1.319 ± 0.756
3.958AsnGly: 3.958 ± 0.933
3.298AsnHis: 3.298 ± 1.813
2.639AsnIle: 2.639 ± 1.132
1.319AsnLys: 1.319 ± 0.698
2.639AsnLeu: 2.639 ± 0.94
1.319AsnMet: 1.319 ± 0.741
2.639AsnAsn: 2.639 ± 1.35
2.639AsnPro: 2.639 ± 0.838
0.66AsnGln: 0.66 ± 0.522
3.298AsnArg: 3.298 ± 1.165
2.639AsnSer: 2.639 ± 1.081
1.979AsnThr: 1.979 ± 1.105
4.617AsnVal: 4.617 ± 1.551
0.0AsnTrp: 0.0 ± 0.0
2.639AsnTyr: 2.639 ± 0.846
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
1.319ProCys: 1.319 ± 0.722
1.319ProAsp: 1.319 ± 0.654
1.979ProGlu: 1.979 ± 0.71
1.319ProPhe: 1.319 ± 0.591
3.298ProGly: 3.298 ± 1.066
2.639ProHis: 2.639 ± 1.432
3.958ProIle: 3.958 ± 2.74
3.958ProLys: 3.958 ± 0.68
2.639ProLeu: 2.639 ± 1.035
1.979ProMet: 1.979 ± 1.098
1.979ProAsn: 1.979 ± 0.949
1.319ProPro: 1.319 ± 0.591
3.958ProGln: 3.958 ± 1.958
3.958ProArg: 3.958 ± 1.54
6.596ProSer: 6.596 ± 1.216
3.958ProThr: 3.958 ± 1.473
3.298ProVal: 3.298 ± 1.641
1.979ProTrp: 1.979 ± 0.567
1.979ProTyr: 1.979 ± 0.735
0.0ProXaa: 0.0 ± 0.0
Gln
4.617GlnAla: 4.617 ± 1.034
0.66GlnCys: 0.66 ± 0.466
0.66GlnAsp: 0.66 ± 0.554
1.319GlnGlu: 1.319 ± 0.686
3.298GlnPhe: 3.298 ± 0.954
1.319GlnGly: 1.319 ± 0.698
1.319GlnHis: 1.319 ± 0.784
3.298GlnIle: 3.298 ± 1.462
1.319GlnLys: 1.319 ± 0.533
1.979GlnLeu: 1.979 ± 0.726
0.0GlnMet: 0.0 ± 0.565
1.319GlnAsn: 1.319 ± 0.698
3.298GlnPro: 3.298 ± 1.105
1.319GlnGln: 1.319 ± 1.17
3.958GlnArg: 3.958 ± 0.68
4.617GlnSer: 4.617 ± 2.273
1.319GlnThr: 1.319 ± 0.756
2.639GlnVal: 2.639 ± 1.063
0.0GlnTrp: 0.0 ± 0.0
0.66GlnTyr: 0.66 ± 0.558
0.0GlnXaa: 0.0 ± 0.0
Arg
4.617ArgAla: 4.617 ± 0.64
0.66ArgCys: 0.66 ± 0.585
7.256ArgAsp: 7.256 ± 1.714
2.639ArgGlu: 2.639 ± 1.309
8.575ArgPhe: 8.575 ± 2.281
6.596ArgGly: 6.596 ± 1.793
1.979ArgHis: 1.979 ± 0.748
3.298ArgIle: 3.298 ± 1.296
1.979ArgLys: 1.979 ± 0.95
3.298ArgLeu: 3.298 ± 1.798
2.639ArgMet: 2.639 ± 1.132
1.319ArgAsn: 1.319 ± 0.654
5.937ArgPro: 5.937 ± 1.186
0.66ArgGln: 0.66 ± 0.585
9.894ArgArg: 9.894 ± 3.823
7.256ArgSer: 7.256 ± 1.165
5.277ArgThr: 5.277 ± 1.09
6.596ArgVal: 6.596 ± 1.403
0.0ArgTrp: 0.0 ± 0.0
1.319ArgTyr: 1.319 ± 0.932
0.0ArgXaa: 0.0 ± 0.0
Ser
8.575SerAla: 8.575 ± 3.921
1.979SerCys: 1.979 ± 0.984
3.298SerAsp: 3.298 ± 0.813
0.66SerGlu: 0.66 ± 0.585
3.298SerPhe: 3.298 ± 0.867
3.958SerGly: 3.958 ± 0.837
3.298SerHis: 3.298 ± 0.813
3.958SerIle: 3.958 ± 1.199
3.958SerLys: 3.958 ± 1.968
9.235SerLeu: 9.235 ± 2.426
0.66SerMet: 0.66 ± 0.558
6.596SerAsn: 6.596 ± 1.444
5.937SerPro: 5.937 ± 1.534
1.979SerGln: 1.979 ± 1.054
9.894SerArg: 9.894 ± 2.755
12.533SerSer: 12.533 ± 2.768
5.277SerThr: 5.277 ± 2.768
4.617SerVal: 4.617 ± 1.81
2.639SerTrp: 2.639 ± 1.182
3.298SerTyr: 3.298 ± 1.058
0.0SerXaa: 0.0 ± 0.0
Thr
2.639ThrAla: 2.639 ± 1.154
0.66ThrCys: 0.66 ± 0.663
1.979ThrAsp: 1.979 ± 1.211
1.979ThrGlu: 1.979 ± 0.567
3.298ThrPhe: 3.298 ± 0.828
4.617ThrGly: 4.617 ± 1.558
4.617ThrHis: 4.617 ± 1.727
0.66ThrIle: 0.66 ± 0.554
2.639ThrLys: 2.639 ± 0.818
3.958ThrLeu: 3.958 ± 0.711
0.66ThrMet: 0.66 ± 0.522
3.958ThrAsn: 3.958 ± 0.837
3.298ThrPro: 3.298 ± 1.208
1.979ThrGln: 1.979 ± 0.489
2.639ThrArg: 2.639 ± 1.119
1.319ThrSer: 1.319 ± 1.326
2.639ThrThr: 2.639 ± 0.931
4.617ThrVal: 4.617 ± 1.613
1.319ThrTrp: 1.319 ± 0.946
3.958ThrTyr: 3.958 ± 1.102
0.0ThrXaa: 0.0 ± 0.0
Val
3.958ValAla: 3.958 ± 1.386
0.0ValCys: 0.0 ± 0.0
3.298ValAsp: 3.298 ± 1.15
2.639ValGlu: 2.639 ± 0.633
2.639ValPhe: 2.639 ± 0.76
4.617ValGly: 4.617 ± 0.792
1.319ValHis: 1.319 ± 0.662
3.298ValIle: 3.298 ± 1.404
4.617ValLys: 4.617 ± 1.447
7.256ValLeu: 7.256 ± 1.15
1.979ValMet: 1.979 ± 1.204
1.979ValAsn: 1.979 ± 1.204
4.617ValPro: 4.617 ± 0.752
6.596ValGln: 6.596 ± 2.075
3.298ValArg: 3.298 ± 1.327
5.277ValSer: 5.277 ± 1.281
2.639ValThr: 2.639 ± 1.432
3.298ValVal: 3.298 ± 2.329
1.319ValTrp: 1.319 ± 0.716
4.617ValTyr: 4.617 ± 1.363
0.0ValXaa: 0.0 ± 0.0
Trp
2.639TrpAla: 2.639 ± 0.994
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
1.319TrpGlu: 1.319 ± 0.756
0.0TrpPhe: 0.0 ± 0.0
0.66TrpGly: 0.66 ± 0.522
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
1.319TrpLys: 1.319 ± 0.591
0.66TrpLeu: 0.66 ± 0.558
1.319TrpMet: 1.319 ± 0.722
0.66TrpAsn: 0.66 ± 0.663
0.0TrpPro: 0.0 ± 0.0
0.66TrpGln: 0.66 ± 0.522
1.979TrpArg: 1.979 ± 1.185
0.66TrpSer: 0.66 ± 0.466
1.979TrpThr: 1.979 ± 0.742
1.319TrpVal: 1.319 ± 0.654
0.0TrpTrp: 0.0 ± 0.0
0.66TrpTyr: 0.66 ± 0.663
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.639TyrAla: 2.639 ± 1.097
0.66TyrCys: 0.66 ± 0.466
1.979TyrAsp: 1.979 ± 0.827
1.319TyrGlu: 1.319 ± 1.116
3.298TyrPhe: 3.298 ± 0.852
1.979TyrGly: 1.979 ± 0.567
0.66TyrHis: 0.66 ± 0.601
3.298TyrIle: 3.298 ± 1.135
0.66TyrLys: 0.66 ± 0.522
2.639TyrLeu: 2.639 ± 1.555
1.979TyrMet: 1.979 ± 0.836
1.319TyrAsn: 1.319 ± 0.654
1.979TyrPro: 1.979 ± 0.815
1.319TyrGln: 1.319 ± 0.533
5.937TyrArg: 5.937 ± 2.366
2.639TyrSer: 2.639 ± 0.933
0.66TyrThr: 0.66 ± 0.601
1.979TyrVal: 1.979 ± 0.76
0.0TyrTrp: 0.0 ± 0.0
1.319TyrTyr: 1.319 ± 0.662
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1517 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski