Amino acid dipepetide frequency for Fowl adenovirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.144AlaAla: 7.144 ± 0.966
1.261AlaCys: 1.261 ± 0.495
4.37AlaAsp: 4.37 ± 0.688
4.791AlaGlu: 4.791 ± 0.666
3.026AlaPhe: 3.026 ± 0.374
4.623AlaGly: 4.623 ± 0.807
1.429AlaHis: 1.429 ± 0.333
4.286AlaIle: 4.286 ± 0.807
2.521AlaLys: 2.521 ± 0.467
7.564AlaLeu: 7.564 ± 1.064
2.017AlaMet: 2.017 ± 0.717
3.698AlaAsn: 3.698 ± 0.506
5.547AlaPro: 5.547 ± 0.801
2.69AlaGln: 2.69 ± 0.538
4.202AlaArg: 4.202 ± 0.598
5.463AlaSer: 5.463 ± 0.716
4.37AlaThr: 4.37 ± 0.548
5.211AlaVal: 5.211 ± 0.599
0.756AlaTrp: 0.756 ± 0.237
3.446AlaTyr: 3.446 ± 0.428
0.0AlaXaa: 0.0 ± 0.0
Cys
1.093CysAla: 1.093 ± 0.337
0.504CysCys: 0.504 ± 0.232
1.093CysAsp: 1.093 ± 0.34
0.336CysGlu: 0.336 ± 0.176
0.925CysPhe: 0.925 ± 0.23
1.345CysGly: 1.345 ± 0.356
0.84CysHis: 0.84 ± 0.317
0.42CysIle: 0.42 ± 0.204
0.756CysLys: 0.756 ± 0.268
1.009CysLeu: 1.009 ± 0.28
0.672CysMet: 0.672 ± 0.322
0.588CysAsn: 0.588 ± 0.259
1.345CysPro: 1.345 ± 0.385
0.672CysGln: 0.672 ± 0.253
1.429CysArg: 1.429 ± 0.418
1.177CysSer: 1.177 ± 0.215
1.177CysThr: 1.177 ± 0.437
1.261CysVal: 1.261 ± 0.438
0.336CysTrp: 0.336 ± 0.146
0.925CysTyr: 0.925 ± 0.25
0.0CysXaa: 0.0 ± 0.0
Asp
4.455AspAla: 4.455 ± 0.544
0.756AspCys: 0.756 ± 0.221
2.69AspAsp: 2.69 ± 0.536
3.194AspGlu: 3.194 ± 0.811
2.69AspPhe: 2.69 ± 0.375
4.118AspGly: 4.118 ± 0.628
1.597AspHis: 1.597 ± 0.346
2.69AspIle: 2.69 ± 0.462
2.101AspLys: 2.101 ± 0.463
4.37AspLeu: 4.37 ± 0.537
1.093AspMet: 1.093 ± 0.238
1.513AspAsn: 1.513 ± 0.385
4.875AspPro: 4.875 ± 0.721
2.101AspGln: 2.101 ± 0.388
3.95AspArg: 3.95 ± 0.607
4.37AspSer: 4.37 ± 0.601
3.446AspThr: 3.446 ± 0.598
3.194AspVal: 3.194 ± 0.55
0.588AspTrp: 0.588 ± 0.168
1.933AspTyr: 1.933 ± 0.409
0.0AspXaa: 0.0 ± 0.0
Glu
4.034GluAla: 4.034 ± 0.674
0.504GluCys: 0.504 ± 0.183
3.53GluAsp: 3.53 ± 0.574
7.144GluGlu: 7.144 ± 1.87
1.513GluPhe: 1.513 ± 0.394
3.95GluGly: 3.95 ± 0.481
1.345GluHis: 1.345 ± 0.317
2.521GluIle: 2.521 ± 0.355
1.933GluLys: 1.933 ± 0.42
5.883GluLeu: 5.883 ± 0.681
1.261GluMet: 1.261 ± 0.309
3.53GluAsn: 3.53 ± 0.599
2.521GluPro: 2.521 ± 0.529
2.101GluGln: 2.101 ± 0.551
3.698GluArg: 3.698 ± 0.761
4.791GluSer: 4.791 ± 0.784
3.194GluThr: 3.194 ± 0.542
3.026GluVal: 3.026 ± 0.583
0.925GluTrp: 0.925 ± 0.259
2.101GluTyr: 2.101 ± 0.379
0.0GluXaa: 0.0 ± 0.0
Phe
2.942PheAla: 2.942 ± 0.448
0.504PheCys: 0.504 ± 0.191
3.194PheAsp: 3.194 ± 0.649
2.353PheGlu: 2.353 ± 0.405
1.681PhePhe: 1.681 ± 0.316
1.513PheGly: 1.513 ± 0.352
1.513PheHis: 1.513 ± 0.346
1.093PheIle: 1.093 ± 0.254
2.101PheLys: 2.101 ± 0.392
4.202PheLeu: 4.202 ± 0.68
1.093PheMet: 1.093 ± 0.309
2.101PheAsn: 2.101 ± 0.36
2.269PhePro: 2.269 ± 0.489
1.009PheGln: 1.009 ± 0.293
3.446PheArg: 3.446 ± 0.407
2.101PheSer: 2.101 ± 0.378
2.017PheThr: 2.017 ± 0.381
3.446PheVal: 3.446 ± 0.539
1.093PheTrp: 1.093 ± 0.304
1.849PheTyr: 1.849 ± 0.288
0.0PheXaa: 0.0 ± 0.0
Gly
6.724GlyAla: 6.724 ± 0.857
0.672GlyCys: 0.672 ± 0.281
2.942GlyAsp: 2.942 ± 0.637
3.698GlyGlu: 3.698 ± 0.986
2.269GlyPhe: 2.269 ± 0.375
6.808GlyGly: 6.808 ± 0.932
1.177GlyHis: 1.177 ± 0.29
2.185GlyIle: 2.185 ± 0.471
1.849GlyLys: 1.849 ± 0.455
4.286GlyLeu: 4.286 ± 0.794
1.429GlyMet: 1.429 ± 0.28
2.605GlyAsn: 2.605 ± 0.465
2.858GlyPro: 2.858 ± 0.527
1.765GlyGln: 1.765 ± 0.372
4.37GlyArg: 4.37 ± 0.6
4.539GlySer: 4.539 ± 0.684
4.202GlyThr: 4.202 ± 0.63
5.631GlyVal: 5.631 ± 0.893
1.345GlyTrp: 1.345 ± 0.268
2.942GlyTyr: 2.942 ± 0.428
0.0GlyXaa: 0.0 ± 0.0
His
1.345HisAla: 1.345 ± 0.25
0.588HisCys: 0.588 ± 0.224
1.597HisAsp: 1.597 ± 0.325
1.177HisGlu: 1.177 ± 0.314
0.672HisPhe: 0.672 ± 0.216
1.513HisGly: 1.513 ± 0.372
1.177HisHis: 1.177 ± 0.284
1.009HisIle: 1.009 ± 0.261
0.504HisLys: 0.504 ± 0.201
2.101HisLeu: 2.101 ± 0.391
0.336HisMet: 0.336 ± 0.149
1.345HisAsn: 1.345 ± 0.249
1.597HisPro: 1.597 ± 0.416
1.009HisGln: 1.009 ± 0.398
2.101HisArg: 2.101 ± 0.372
1.093HisSer: 1.093 ± 0.226
1.345HisThr: 1.345 ± 0.325
2.101HisVal: 2.101 ± 0.522
0.168HisTrp: 0.168 ± 0.115
1.009HisTyr: 1.009 ± 0.189
0.0HisXaa: 0.0 ± 0.0
Ile
3.782IleAla: 3.782 ± 0.605
0.925IleCys: 0.925 ± 0.304
2.101IleAsp: 2.101 ± 0.397
2.017IleGlu: 2.017 ± 0.308
1.177IlePhe: 1.177 ± 0.296
2.269IleGly: 2.269 ± 0.391
0.84IleHis: 0.84 ± 0.263
1.261IleIle: 1.261 ± 0.294
1.177IleLys: 1.177 ± 0.328
3.614IleLeu: 3.614 ± 0.51
0.672IleMet: 0.672 ± 0.28
1.681IleAsn: 1.681 ± 0.414
3.446IlePro: 3.446 ± 0.508
1.345IleGln: 1.345 ± 0.37
3.194IleArg: 3.194 ± 0.462
2.858IleSer: 2.858 ± 0.463
2.353IleThr: 2.353 ± 0.525
2.774IleVal: 2.774 ± 0.363
0.504IleTrp: 0.504 ± 0.148
1.597IleTyr: 1.597 ± 0.273
0.0IleXaa: 0.0 ± 0.0
Lys
2.353LysAla: 2.353 ± 0.574
0.84LysCys: 0.84 ± 0.272
1.849LysAsp: 1.849 ± 0.319
2.269LysGlu: 2.269 ± 0.476
2.101LysPhe: 2.101 ± 0.391
2.101LysGly: 2.101 ± 0.49
0.42LysHis: 0.42 ± 0.166
1.429LysIle: 1.429 ± 0.264
2.017LysLys: 2.017 ± 0.607
3.614LysLeu: 3.614 ± 0.418
1.093LysMet: 1.093 ± 0.28
1.765LysAsn: 1.765 ± 0.337
1.933LysPro: 1.933 ± 0.357
1.009LysGln: 1.009 ± 0.265
3.362LysArg: 3.362 ± 0.645
1.765LysSer: 1.765 ± 0.541
2.774LysThr: 2.774 ± 0.475
1.933LysVal: 1.933 ± 0.405
0.588LysTrp: 0.588 ± 0.217
1.849LysTyr: 1.849 ± 0.448
0.0LysXaa: 0.0 ± 0.0
Leu
6.388LeuAla: 6.388 ± 0.616
1.513LeuCys: 1.513 ± 0.392
4.202LeuAsp: 4.202 ± 0.525
4.118LeuGlu: 4.118 ± 0.505
4.118LeuPhe: 4.118 ± 0.548
4.539LeuGly: 4.539 ± 0.574
2.353LeuHis: 2.353 ± 0.513
3.11LeuIle: 3.11 ± 0.434
3.782LeuLys: 3.782 ± 0.652
7.732LeuLeu: 7.732 ± 0.744
2.101LeuMet: 2.101 ± 0.383
3.866LeuAsn: 3.866 ± 0.367
5.127LeuPro: 5.127 ± 0.464
4.286LeuGln: 4.286 ± 0.455
6.556LeuArg: 6.556 ± 0.959
6.808LeuSer: 6.808 ± 0.524
6.64LeuThr: 6.64 ± 0.83
4.539LeuVal: 4.539 ± 0.609
1.513LeuTrp: 1.513 ± 0.259
3.446LeuTyr: 3.446 ± 0.53
0.0LeuXaa: 0.0 ± 0.0
Met
2.437MetAla: 2.437 ± 0.479
0.336MetCys: 0.336 ± 0.176
1.513MetAsp: 1.513 ± 0.31
1.093MetGlu: 1.093 ± 0.326
1.177MetPhe: 1.177 ± 0.288
1.681MetGly: 1.681 ± 0.382
0.84MetHis: 0.84 ± 0.284
0.756MetIle: 0.756 ± 0.293
1.093MetLys: 1.093 ± 0.244
2.353MetLeu: 2.353 ± 0.323
0.42MetMet: 0.42 ± 0.145
0.672MetAsn: 0.672 ± 0.182
1.009MetPro: 1.009 ± 0.281
1.093MetGln: 1.093 ± 0.229
2.017MetArg: 2.017 ± 0.378
1.681MetSer: 1.681 ± 0.371
1.177MetThr: 1.177 ± 0.322
1.429MetVal: 1.429 ± 0.361
0.084MetTrp: 0.084 ± 0.077
1.093MetTyr: 1.093 ± 0.278
0.0MetXaa: 0.0 ± 0.0
Asn
3.362AsnAla: 3.362 ± 0.533
1.093AsnCys: 1.093 ± 0.354
2.017AsnAsp: 2.017 ± 0.45
1.933AsnGlu: 1.933 ± 0.494
1.513AsnPhe: 1.513 ± 0.464
2.774AsnGly: 2.774 ± 0.72
0.84AsnHis: 0.84 ± 0.223
1.513AsnIle: 1.513 ± 0.456
1.681AsnLys: 1.681 ± 0.382
3.194AsnLeu: 3.194 ± 0.591
0.925AsnMet: 0.925 ± 0.313
2.017AsnAsn: 2.017 ± 0.435
3.866AsnPro: 3.866 ± 0.684
1.261AsnGln: 1.261 ± 0.337
3.026AsnArg: 3.026 ± 0.531
2.858AsnSer: 2.858 ± 0.685
2.942AsnThr: 2.942 ± 0.526
3.95AsnVal: 3.95 ± 0.596
0.756AsnTrp: 0.756 ± 0.283
2.269AsnTyr: 2.269 ± 0.464
0.0AsnXaa: 0.0 ± 0.0
Pro
5.967ProAla: 5.967 ± 0.857
0.756ProCys: 0.756 ± 0.215
3.362ProAsp: 3.362 ± 0.335
4.707ProGlu: 4.707 ± 0.664
3.194ProPhe: 3.194 ± 0.562
2.269ProGly: 2.269 ± 0.292
1.429ProHis: 1.429 ± 0.361
2.605ProIle: 2.605 ± 0.664
1.597ProLys: 1.597 ± 0.483
4.791ProLeu: 4.791 ± 0.755
1.261ProMet: 1.261 ± 0.417
3.026ProAsn: 3.026 ± 0.49
6.051ProPro: 6.051 ± 1.022
2.69ProGln: 2.69 ± 0.571
3.95ProArg: 3.95 ± 0.486
5.295ProSer: 5.295 ± 0.667
3.866ProThr: 3.866 ± 0.52
4.286ProVal: 4.286 ± 0.664
0.42ProTrp: 0.42 ± 0.189
3.026ProTyr: 3.026 ± 0.533
0.0ProXaa: 0.0 ± 0.0
Gln
2.69GlnAla: 2.69 ± 0.542
0.504GlnCys: 0.504 ± 0.15
1.849GlnAsp: 1.849 ± 0.346
2.353GlnGlu: 2.353 ± 0.555
1.261GlnPhe: 1.261 ± 0.367
1.849GlnGly: 1.849 ± 0.385
0.84GlnHis: 0.84 ± 0.397
1.597GlnIle: 1.597 ± 0.317
1.513GlnLys: 1.513 ± 0.273
3.782GlnLeu: 3.782 ± 0.494
1.429GlnMet: 1.429 ± 0.363
2.101GlnAsn: 2.101 ± 0.516
1.597GlnPro: 1.597 ± 0.419
2.185GlnGln: 2.185 ± 0.71
2.269GlnArg: 2.269 ± 0.444
2.185GlnSer: 2.185 ± 0.384
2.605GlnThr: 2.605 ± 0.54
1.849GlnVal: 1.849 ± 0.385
0.336GlnTrp: 0.336 ± 0.131
1.849GlnTyr: 1.849 ± 0.446
0.0GlnXaa: 0.0 ± 0.0
Arg
5.127ArgAla: 5.127 ± 0.788
1.429ArgCys: 1.429 ± 0.437
3.782ArgAsp: 3.782 ± 0.632
3.698ArgGlu: 3.698 ± 0.724
2.69ArgPhe: 2.69 ± 0.43
4.623ArgGly: 4.623 ± 0.827
2.353ArgHis: 2.353 ± 0.603
2.942ArgIle: 2.942 ± 0.489
3.026ArgLys: 3.026 ± 0.703
6.388ArgLeu: 6.388 ± 0.92
2.185ArgMet: 2.185 ± 0.337
3.026ArgAsn: 3.026 ± 0.688
4.034ArgPro: 4.034 ± 0.689
3.11ArgGln: 3.11 ± 0.487
8.321ArgArg: 8.321 ± 1.681
5.211ArgSer: 5.211 ± 0.637
3.446ArgThr: 3.446 ± 0.429
5.043ArgVal: 5.043 ± 0.513
0.925ArgTrp: 0.925 ± 0.208
2.353ArgTyr: 2.353 ± 0.401
0.0ArgXaa: 0.0 ± 0.0
Ser
4.623SerAla: 4.623 ± 0.559
1.345SerCys: 1.345 ± 0.294
5.127SerAsp: 5.127 ± 0.825
4.623SerGlu: 4.623 ± 0.74
2.858SerPhe: 2.858 ± 0.537
6.892SerGly: 6.892 ± 0.777
1.009SerHis: 1.009 ± 0.375
2.774SerIle: 2.774 ± 0.483
3.278SerLys: 3.278 ± 0.562
5.715SerLeu: 5.715 ± 0.777
1.765SerMet: 1.765 ± 0.449
2.437SerAsn: 2.437 ± 0.682
4.034SerPro: 4.034 ± 0.576
1.849SerGln: 1.849 ± 0.417
5.715SerArg: 5.715 ± 0.629
6.304SerSer: 6.304 ± 1.12
4.37SerThr: 4.37 ± 0.688
3.614SerVal: 3.614 ± 0.535
1.009SerTrp: 1.009 ± 0.313
1.933SerTyr: 1.933 ± 0.364
0.0SerXaa: 0.0 ± 0.0
Thr
6.051ThrAla: 6.051 ± 0.833
1.429ThrCys: 1.429 ± 0.334
2.605ThrAsp: 2.605 ± 0.57
3.866ThrGlu: 3.866 ± 0.534
2.605ThrPhe: 2.605 ± 0.512
4.455ThrGly: 4.455 ± 0.776
1.093ThrHis: 1.093 ± 0.32
2.605ThrIle: 2.605 ± 0.354
1.261ThrLys: 1.261 ± 0.358
5.379ThrLeu: 5.379 ± 0.78
1.093ThrMet: 1.093 ± 0.29
2.69ThrAsn: 2.69 ± 0.564
3.866ThrPro: 3.866 ± 0.653
2.185ThrGln: 2.185 ± 0.518
3.866ThrArg: 3.866 ± 0.509
3.866ThrSer: 3.866 ± 0.885
3.278ThrThr: 3.278 ± 0.521
4.791ThrVal: 4.791 ± 0.63
0.672ThrTrp: 0.672 ± 0.284
2.774ThrTyr: 2.774 ± 0.549
0.0ThrXaa: 0.0 ± 0.0
Val
4.707ValAla: 4.707 ± 0.69
1.429ValCys: 1.429 ± 0.317
3.866ValAsp: 3.866 ± 0.527
3.698ValGlu: 3.698 ± 0.502
3.11ValPhe: 3.11 ± 0.455
3.782ValGly: 3.782 ± 0.538
1.261ValHis: 1.261 ± 0.257
3.11ValIle: 3.11 ± 0.52
2.353ValLys: 2.353 ± 0.522
6.388ValLeu: 6.388 ± 0.634
1.261ValMet: 1.261 ± 0.324
2.774ValAsn: 2.774 ± 0.574
4.959ValPro: 4.959 ± 0.604
2.774ValGln: 2.774 ± 0.501
4.455ValArg: 4.455 ± 0.588
4.707ValSer: 4.707 ± 0.615
4.118ValThr: 4.118 ± 0.638
4.455ValVal: 4.455 ± 0.631
0.84ValTrp: 0.84 ± 0.239
2.521ValTyr: 2.521 ± 0.426
0.0ValXaa: 0.0 ± 0.0
Trp
0.756TrpAla: 0.756 ± 0.279
0.42TrpCys: 0.42 ± 0.202
1.009TrpAsp: 1.009 ± 0.238
0.588TrpGlu: 0.588 ± 0.142
0.42TrpPhe: 0.42 ± 0.178
0.84TrpGly: 0.84 ± 0.253
0.252TrpHis: 0.252 ± 0.157
0.588TrpIle: 0.588 ± 0.206
0.504TrpLys: 0.504 ± 0.261
1.177TrpLeu: 1.177 ± 0.271
0.168TrpMet: 0.168 ± 0.135
0.672TrpAsn: 0.672 ± 0.238
0.588TrpPro: 0.588 ± 0.344
0.672TrpGln: 0.672 ± 0.275
1.093TrpArg: 1.093 ± 0.279
1.093TrpSer: 1.093 ± 0.245
0.672TrpThr: 0.672 ± 0.212
1.093TrpVal: 1.093 ± 0.345
0.084TrpTrp: 0.084 ± 0.077
0.84TrpTyr: 0.84 ± 0.267
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.437TyrAla: 2.437 ± 0.345
1.093TyrCys: 1.093 ± 0.271
3.026TyrAsp: 3.026 ± 0.729
1.849TyrGlu: 1.849 ± 0.41
2.521TyrPhe: 2.521 ± 0.448
2.353TyrGly: 2.353 ± 0.467
1.177TyrHis: 1.177 ± 0.262
1.093TyrIle: 1.093 ± 0.288
2.017TyrLys: 2.017 ± 0.443
3.194TyrLeu: 3.194 ± 0.583
1.597TyrMet: 1.597 ± 0.46
1.681TyrAsn: 1.681 ± 0.406
3.026TyrPro: 3.026 ± 0.428
0.84TyrGln: 0.84 ± 0.238
2.69TyrArg: 2.69 ± 0.408
3.11TyrSer: 3.11 ± 0.535
2.437TyrThr: 2.437 ± 0.505
2.942TyrVal: 2.942 ± 0.375
0.672TyrTrp: 0.672 ± 0.228
1.261TyrTyr: 1.261 ± 0.167
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 34 proteins (11899 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski