Amino acid dipepetide frequency for Monkey B-lymphotropic papovavirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
0.0AlaAla: 0.0 ± 0.0
1.656AlaCys: 1.656 ± 0.977
3.311AlaAsp: 3.311 ± 0.541
1.656AlaGlu: 1.656 ± 1.518
1.656AlaPhe: 1.656 ± 0.977
1.656AlaGly: 1.656 ± 0.977
1.656AlaHis: 1.656 ± 1.518
3.311AlaIle: 3.311 ± 1.954
1.656AlaLys: 1.656 ± 0.977
4.967AlaLeu: 4.967 ± 2.059
0.0AlaMet: 0.0 ± 0.951
0.0AlaAsn: 0.0 ± 0.0
6.623AlaPro: 6.623 ± 1.082
1.656AlaGln: 1.656 ± 1.518
8.278AlaArg: 8.278 ± 7.591
3.311AlaSer: 3.311 ± 1.954
6.623AlaThr: 6.623 ± 1.082
11.589AlaVal: 11.589 ± 3.142
0.0AlaTrp: 0.0 ± 0.0
1.656AlaTyr: 1.656 ± 0.977
0.0AlaXaa: 0.0 ± 0.0
Cys
1.656CysAla: 1.656 ± 0.977
0.0CysCys: 0.0 ± 0.0
1.656CysAsp: 1.656 ± 0.977
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
3.311CysLys: 3.311 ± 1.954
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
3.311CysPro: 3.311 ± 1.954
1.656CysGln: 1.656 ± 0.977
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.656CysVal: 1.656 ± 0.977
0.0CysTrp: 0.0 ± 0.0
1.656CysTyr: 1.656 ± 0.977
0.0CysXaa: 0.0 ± 0.0
Asp
1.656AspAla: 1.656 ± 0.977
0.0AspCys: 0.0 ± 0.0
1.656AspAsp: 1.656 ± 0.977
3.311AspGlu: 3.311 ± 0.541
1.656AspPhe: 1.656 ± 1.518
4.967AspGly: 4.967 ± 0.436
0.0AspHis: 0.0 ± 0.0
3.311AspIle: 3.311 ± 0.541
4.967AspLys: 4.967 ± 2.931
3.311AspLeu: 3.311 ± 1.954
3.311AspMet: 3.311 ± 1.954
0.0AspAsn: 0.0 ± 0.0
4.967AspPro: 4.967 ± 2.931
0.0AspGln: 0.0 ± 0.0
0.0AspArg: 0.0 ± 0.0
0.0AspSer: 0.0 ± 0.0
3.311AspThr: 3.311 ± 1.954
1.656AspVal: 1.656 ± 0.977
3.311AspTrp: 3.311 ± 3.036
3.311AspTyr: 3.311 ± 3.036
0.0AspXaa: 0.0 ± 0.0
Glu
3.311GluAla: 3.311 ± 1.954
0.0GluCys: 0.0 ± 0.0
4.967GluAsp: 4.967 ± 0.436
3.311GluGlu: 3.311 ± 0.541
0.0GluPhe: 0.0 ± 0.0
6.623GluGly: 6.623 ± 1.413
1.656GluHis: 1.656 ± 1.518
0.0GluIle: 0.0 ± 0.0
1.656GluLys: 1.656 ± 1.518
6.623GluLeu: 6.623 ± 3.577
0.0GluMet: 0.0 ± 0.0
6.623GluAsn: 6.623 ± 1.082
4.967GluPro: 4.967 ± 2.059
0.0GluGln: 0.0 ± 0.0
0.0GluArg: 0.0 ± 0.0
1.656GluSer: 1.656 ± 1.518
1.656GluThr: 1.656 ± 0.977
11.589GluVal: 11.589 ± 1.849
0.0GluTrp: 0.0 ± 0.0
3.311GluTyr: 3.311 ± 3.036
0.0GluXaa: 0.0 ± 0.0
Phe
1.656PheAla: 1.656 ± 0.977
1.656PheCys: 1.656 ± 0.977
0.0PheAsp: 0.0 ± 0.0
3.311PheGlu: 3.311 ± 0.541
1.656PhePhe: 1.656 ± 0.977
0.0PheGly: 0.0 ± 0.0
1.656PheHis: 1.656 ± 1.518
0.0PheIle: 0.0 ± 0.0
0.0PheLys: 0.0 ± 0.0
1.656PheLeu: 1.656 ± 0.977
0.0PheMet: 0.0 ± 0.0
1.656PheAsn: 1.656 ± 0.977
3.311PhePro: 3.311 ± 3.036
0.0PheGln: 0.0 ± 0.0
0.0PheArg: 0.0 ± 0.0
4.967PheSer: 4.967 ± 0.436
4.967PheThr: 4.967 ± 0.436
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.623GlyAla: 6.623 ± 1.082
1.656GlyCys: 1.656 ± 0.977
4.967GlyAsp: 4.967 ± 0.436
4.967GlyGlu: 4.967 ± 2.059
1.656GlyPhe: 1.656 ± 1.518
8.278GlyGly: 8.278 ± 2.39
0.0GlyHis: 0.0 ± 0.0
1.656GlyIle: 1.656 ± 0.977
3.311GlyLys: 3.311 ± 1.954
9.934GlyLeu: 9.934 ± 3.367
0.0GlyMet: 0.0 ± 0.0
3.311GlyAsn: 3.311 ± 1.954
6.623GlyPro: 6.623 ± 1.082
8.278GlyGln: 8.278 ± 2.6
1.656GlyArg: 1.656 ± 1.518
3.311GlySer: 3.311 ± 1.954
4.967GlyThr: 4.967 ± 2.931
6.623GlyVal: 6.623 ± 3.908
0.0GlyTrp: 0.0 ± 0.0
3.311GlyTyr: 3.311 ± 0.541
0.0GlyXaa: 0.0 ± 0.0
His
1.656HisAla: 1.656 ± 1.518
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
1.656HisIle: 1.656 ± 1.518
0.0HisLys: 0.0 ± 0.0
1.656HisLeu: 1.656 ± 1.518
1.656HisMet: 1.656 ± 0.977
0.0HisAsn: 0.0 ± 0.0
0.0HisPro: 0.0 ± 0.0
3.311HisGln: 3.311 ± 0.541
0.0HisArg: 0.0 ± 0.0
0.0HisSer: 0.0 ± 0.0
3.311HisThr: 3.311 ± 0.541
0.0HisVal: 0.0 ± 0.0
0.0HisTrp: 0.0 ± 0.0
1.656HisTyr: 1.656 ± 1.518
0.0HisXaa: 0.0 ± 0.0
Ile
3.311IleAla: 3.311 ± 0.541
0.0IleCys: 0.0 ± 0.0
0.0IleAsp: 0.0 ± 0.0
1.656IleGlu: 1.656 ± 0.977
1.656IlePhe: 1.656 ± 0.977
1.656IleGly: 1.656 ± 1.518
0.0IleHis: 0.0 ± 0.0
0.0IleIle: 0.0 ± 0.0
3.311IleLys: 3.311 ± 1.954
3.311IleLeu: 3.311 ± 0.541
0.0IleMet: 0.0 ± 0.0
1.656IleAsn: 1.656 ± 0.977
3.311IlePro: 3.311 ± 1.954
3.311IleGln: 3.311 ± 0.541
0.0IleArg: 0.0 ± 0.0
1.656IleSer: 1.656 ± 0.977
3.311IleThr: 3.311 ± 0.541
1.656IleVal: 1.656 ± 0.977
0.0IleTrp: 0.0 ± 0.0
3.311IleTyr: 3.311 ± 0.541
0.0IleXaa: 0.0 ± 0.0
Lys
6.623LysAla: 6.623 ± 1.413
0.0LysCys: 0.0 ± 0.0
1.656LysAsp: 1.656 ± 0.977
1.656LysGlu: 1.656 ± 1.518
1.656LysPhe: 1.656 ± 0.977
4.967LysGly: 4.967 ± 2.931
0.0LysHis: 0.0 ± 0.0
0.0LysIle: 0.0 ± 0.0
4.967LysLys: 4.967 ± 2.059
4.967LysLeu: 4.967 ± 0.436
0.0LysMet: 0.0 ± 0.0
8.278LysAsn: 8.278 ± 0.105
1.656LysPro: 1.656 ± 0.977
0.0LysGln: 0.0 ± 0.0
4.967LysArg: 4.967 ± 0.436
0.0LysSer: 0.0 ± 0.0
3.311LysThr: 3.311 ± 1.954
0.0LysVal: 0.0 ± 0.0
0.0LysTrp: 0.0 ± 0.0
3.311LysTyr: 3.311 ± 1.954
0.0LysXaa: 0.0 ± 0.0
Leu
1.656LeuAla: 1.656 ± 1.518
1.656LeuCys: 1.656 ± 0.977
6.623LeuAsp: 6.623 ± 1.413
4.967LeuGlu: 4.967 ± 0.436
4.967LeuPhe: 4.967 ± 2.059
3.311LeuGly: 3.311 ± 3.036
1.656LeuHis: 1.656 ± 0.977
1.656LeuIle: 1.656 ± 1.518
0.0LeuLys: 0.0 ± 0.0
8.278LeuLeu: 8.278 ± 4.885
4.967LeuMet: 4.967 ± 0.436
9.934LeuAsn: 9.934 ± 0.872
11.589LeuPro: 11.589 ± 1.849
3.311LeuGln: 3.311 ± 0.541
3.311LeuArg: 3.311 ± 0.541
3.311LeuSer: 3.311 ± 0.541
1.656LeuThr: 1.656 ± 1.518
6.623LeuVal: 6.623 ± 1.413
0.0LeuTrp: 0.0 ± 0.0
3.311LeuTyr: 3.311 ± 0.541
0.0LeuXaa: 0.0 ± 0.0
Met
3.311MetAla: 3.311 ± 0.541
0.0MetCys: 0.0 ± 0.0
0.0MetAsp: 0.0 ± 0.0
1.656MetGlu: 1.656 ± 0.977
1.656MetPhe: 1.656 ± 0.977
1.656MetGly: 1.656 ± 0.977
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
1.656MetLys: 1.656 ± 0.977
1.656MetLeu: 1.656 ± 1.518
1.656MetMet: 1.656 ± 0.753
0.0MetAsn: 0.0 ± 0.0
3.311MetPro: 3.311 ± 0.541
3.311MetGln: 3.311 ± 0.541
1.656MetArg: 1.656 ± 1.518
0.0MetSer: 0.0 ± 0.0
1.656MetThr: 1.656 ± 0.977
0.0MetVal: 0.0 ± 0.0
1.656MetTrp: 1.656 ± 0.977
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
3.311AsnAla: 3.311 ± 3.036
0.0AsnCys: 0.0 ± 0.0
1.656AsnAsp: 1.656 ± 0.977
4.967AsnGlu: 4.967 ± 0.436
0.0AsnPhe: 0.0 ± 0.0
1.656AsnGly: 1.656 ± 0.977
0.0AsnHis: 0.0 ± 0.0
1.656AsnIle: 1.656 ± 0.977
3.311AsnLys: 3.311 ± 0.541
1.656AsnLeu: 1.656 ± 0.977
3.311AsnMet: 3.311 ± 0.541
1.656AsnAsn: 1.656 ± 0.977
4.967AsnPro: 4.967 ± 0.436
3.311AsnGln: 3.311 ± 1.954
6.623AsnArg: 6.623 ± 3.577
4.967AsnSer: 4.967 ± 2.931
3.311AsnThr: 3.311 ± 1.954
1.656AsnVal: 1.656 ± 0.977
0.0AsnTrp: 0.0 ± 0.0
1.656AsnTyr: 1.656 ± 0.977
0.0AsnXaa: 0.0 ± 0.0
Pro
3.311ProAla: 3.311 ± 0.541
1.656ProCys: 1.656 ± 0.977
6.623ProAsp: 6.623 ± 3.908
0.0ProGlu: 0.0 ± 0.0
0.0ProPhe: 0.0 ± 0.0
6.623ProGly: 6.623 ± 1.082
0.0ProHis: 0.0 ± 0.0
3.311ProIle: 3.311 ± 0.541
1.656ProLys: 1.656 ± 0.977
6.623ProLeu: 6.623 ± 1.413
1.656ProMet: 1.656 ± 0.977
1.656ProAsn: 1.656 ± 0.977
4.967ProPro: 4.967 ± 2.059
6.623ProGln: 6.623 ± 1.082
6.623ProArg: 6.623 ± 1.413
8.278ProSer: 8.278 ± 2.6
1.656ProThr: 1.656 ± 1.518
11.589ProVal: 11.589 ± 4.344
1.656ProTrp: 1.656 ± 1.518
3.311ProTyr: 3.311 ± 0.541
0.0ProXaa: 0.0 ± 0.0
Gln
4.967GlnAla: 4.967 ± 4.554
0.0GlnCys: 0.0 ± 0.0
4.967GlnAsp: 4.967 ± 2.059
3.311GlnGlu: 3.311 ± 3.036
1.656GlnPhe: 1.656 ± 0.977
8.278GlnGly: 8.278 ± 4.885
0.0GlnHis: 0.0 ± 0.0
6.623GlnIle: 6.623 ± 1.082
1.656GlnLys: 1.656 ± 1.518
1.656GlnLeu: 1.656 ± 1.518
0.0GlnMet: 0.0 ± 0.0
1.656GlnAsn: 1.656 ± 0.977
1.656GlnPro: 1.656 ± 0.977
0.0GlnGln: 0.0 ± 0.0
4.967GlnArg: 4.967 ± 2.059
1.656GlnSer: 1.656 ± 0.977
1.656GlnThr: 1.656 ± 0.977
3.311GlnVal: 3.311 ± 0.541
0.0GlnTrp: 0.0 ± 0.0
1.656GlnTyr: 1.656 ± 1.518
0.0GlnXaa: 0.0 ± 0.0
Arg
6.623ArgAla: 6.623 ± 6.073
0.0ArgCys: 0.0 ± 0.0
0.0ArgAsp: 0.0 ± 0.0
4.967ArgGlu: 4.967 ± 4.554
0.0ArgPhe: 0.0 ± 0.0
4.967ArgGly: 4.967 ± 2.059
1.656ArgHis: 1.656 ± 1.518
3.311ArgIle: 3.311 ± 1.954
3.311ArgLys: 3.311 ± 1.954
1.656ArgLeu: 1.656 ± 0.977
1.656ArgMet: 1.656 ± 0.977
3.311ArgAsn: 3.311 ± 3.036
1.656ArgPro: 1.656 ± 1.518
4.967ArgGln: 4.967 ± 2.059
4.967ArgArg: 4.967 ± 4.554
9.934ArgSer: 9.934 ± 9.109
1.656ArgThr: 1.656 ± 0.977
1.656ArgVal: 1.656 ± 1.518
1.656ArgTrp: 1.656 ± 1.518
6.623ArgTyr: 6.623 ± 1.413
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
1.656SerCys: 1.656 ± 0.977
1.656SerAsp: 1.656 ± 0.977
3.311SerGlu: 3.311 ± 1.954
4.967SerPhe: 4.967 ± 0.436
8.278SerGly: 8.278 ± 0.105
1.656SerHis: 1.656 ± 1.518
1.656SerIle: 1.656 ± 0.977
8.278SerLys: 8.278 ± 2.6
4.967SerLeu: 4.967 ± 0.436
1.656SerMet: 1.656 ± 1.518
3.311SerAsn: 3.311 ± 1.954
0.0SerPro: 0.0 ± 0.0
0.0SerGln: 0.0 ± 0.0
6.623SerArg: 6.623 ± 6.073
9.934SerSer: 9.934 ± 3.367
3.311SerThr: 3.311 ± 0.541
6.623SerVal: 6.623 ± 1.413
1.656SerTrp: 1.656 ± 0.977
1.656SerTyr: 1.656 ± 1.518
0.0SerXaa: 0.0 ± 0.0
Thr
4.967ThrAla: 4.967 ± 0.436
3.311ThrCys: 3.311 ± 1.954
0.0ThrAsp: 0.0 ± 0.0
3.311ThrGlu: 3.311 ± 1.954
0.0ThrPhe: 0.0 ± 0.0
3.311ThrGly: 3.311 ± 1.954
0.0ThrHis: 0.0 ± 0.0
1.656ThrIle: 1.656 ± 0.977
0.0ThrLys: 0.0 ± 0.0
6.623ThrLeu: 6.623 ± 1.082
0.0ThrMet: 0.0 ± 0.0
4.967ThrAsn: 4.967 ± 0.436
4.967ThrPro: 4.967 ± 0.436
4.967ThrGln: 4.967 ± 0.436
3.311ThrArg: 3.311 ± 0.541
3.311ThrSer: 3.311 ± 3.036
4.967ThrThr: 4.967 ± 2.931
3.311ThrVal: 3.311 ± 1.954
1.656ThrTrp: 1.656 ± 1.518
3.311ThrTyr: 3.311 ± 1.954
0.0ThrXaa: 0.0 ± 0.0
Val
6.623ValAla: 6.623 ± 1.413
0.0ValCys: 0.0 ± 0.0
3.311ValAsp: 3.311 ± 0.541
8.278ValGlu: 8.278 ± 0.105
0.0ValPhe: 0.0 ± 0.0
6.623ValGly: 6.623 ± 1.413
3.311ValHis: 3.311 ± 0.541
1.656ValIle: 1.656 ± 0.977
4.967ValLys: 4.967 ± 2.931
6.623ValLeu: 6.623 ± 1.413
1.656ValMet: 1.656 ± 0.977
1.656ValAsn: 1.656 ± 0.977
4.967ValPro: 4.967 ± 0.436
3.311ValGln: 3.311 ± 0.541
4.967ValArg: 4.967 ± 0.436
6.623ValSer: 6.623 ± 3.908
4.967ValThr: 4.967 ± 0.436
3.311ValVal: 3.311 ± 1.954
3.311ValTrp: 3.311 ± 0.541
0.0ValTyr: 0.0 ± 0.0
0.0ValXaa: 0.0 ± 0.0
Trp
1.656TrpAla: 1.656 ± 1.518
1.656TrpCys: 1.656 ± 0.977
0.0TrpAsp: 0.0 ± 0.0
3.311TrpGlu: 3.311 ± 0.541
1.656TrpPhe: 1.656 ± 1.518
1.656TrpGly: 1.656 ± 1.518
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
1.656TrpMet: 1.656 ± 1.518
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
3.311TrpArg: 3.311 ± 0.541
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
0.0TyrAla: 0.0 ± 0.0
0.0TyrCys: 0.0 ± 0.0
1.656TyrAsp: 1.656 ± 1.518
0.0TyrGlu: 0.0 ± 0.0
1.656TyrPhe: 1.656 ± 0.977
6.623TyrGly: 6.623 ± 1.413
1.656TyrHis: 1.656 ± 0.977
1.656TyrIle: 1.656 ± 0.977
0.0TyrLys: 0.0 ± 0.0
6.623TyrLeu: 6.623 ± 3.577
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
4.967TyrPro: 4.967 ± 2.931
1.656TyrGln: 1.656 ± 1.518
3.311TyrArg: 3.311 ± 3.036
8.278TyrSer: 8.278 ± 0.105
1.656TyrThr: 1.656 ± 1.518
3.311TyrVal: 3.311 ± 0.541
0.0TyrTrp: 0.0 ± 0.0
4.967TyrTyr: 4.967 ± 2.059
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (605 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski