Amino acid dipepetide frequency for Trachymyrmex zeteki

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.001AlaAla: 5.001 ± 0.049
1.245AlaCys: 1.245 ± 0.027
2.835AlaAsp: 2.835 ± 0.024
3.713AlaGlu: 3.713 ± 0.028
2.14AlaPhe: 2.14 ± 0.02
3.306AlaGly: 3.306 ± 0.03
1.396AlaHis: 1.396 ± 0.017
3.665AlaIle: 3.665 ± 0.024
3.591AlaLys: 3.591 ± 0.031
5.536AlaLeu: 5.536 ± 0.044
1.471AlaMet: 1.471 ± 0.015
2.744AlaAsn: 2.744 ± 0.022
2.613AlaPro: 2.613 ± 0.028
2.227AlaGln: 2.227 ± 0.022
3.614AlaArg: 3.614 ± 0.03
4.843AlaSer: 4.843 ± 0.033
3.981AlaThr: 3.981 ± 0.028
3.916AlaVal: 3.916 ± 0.031
0.624AlaTrp: 0.624 ± 0.01
1.646AlaTyr: 1.646 ± 0.019
0.002AlaXaa: 0.002 ± 0.001
Cys
1.169CysAla: 1.169 ± 0.018
0.503CysCys: 0.503 ± 0.011
1.151CysAsp: 1.151 ± 0.021
1.192CysGlu: 1.192 ± 0.018
0.764CysPhe: 0.764 ± 0.013
1.338CysGly: 1.338 ± 0.035
0.559CysHis: 0.559 ± 0.012
1.298CysIle: 1.298 ± 0.028
1.241CysLys: 1.241 ± 0.019
1.889CysLeu: 1.889 ± 0.028
0.442CysMet: 0.442 ± 0.01
1.077CysAsn: 1.077 ± 0.018
1.034CysPro: 1.034 ± 0.029
0.781CysGln: 0.781 ± 0.017
1.244CysArg: 1.244 ± 0.031
1.632CysSer: 1.632 ± 0.026
1.208CysThr: 1.208 ± 0.024
1.288CysVal: 1.288 ± 0.025
0.233CysTrp: 0.233 ± 0.007
0.627CysTyr: 0.627 ± 0.012
0.0CysXaa: 0.0 ± 0.0
Asp
3.031AspAla: 3.031 ± 0.024
1.036AspCys: 1.036 ± 0.02
3.634AspAsp: 3.634 ± 0.043
4.063AspGlu: 4.063 ± 0.034
2.048AspPhe: 2.048 ± 0.02
2.961AspGly: 2.961 ± 0.025
1.13AspHis: 1.13 ± 0.016
3.669AspIle: 3.669 ± 0.03
3.331AspLys: 3.331 ± 0.033
4.611AspLeu: 4.611 ± 0.034
1.208AspMet: 1.208 ± 0.016
2.821AspAsn: 2.821 ± 0.027
2.297AspPro: 2.297 ± 0.029
1.626AspGln: 1.626 ± 0.016
2.831AspArg: 2.831 ± 0.031
4.241AspSer: 4.241 ± 0.037
3.001AspThr: 3.001 ± 0.024
3.551AspVal: 3.551 ± 0.027
0.602AspTrp: 0.602 ± 0.011
1.793AspTyr: 1.793 ± 0.018
0.001AspXaa: 0.001 ± 0.0
Glu
3.765GluAla: 3.765 ± 0.034
1.234GluCys: 1.234 ± 0.03
4.004GluAsp: 4.004 ± 0.036
6.076GluGlu: 6.076 ± 0.076
2.085GluPhe: 2.085 ± 0.019
2.867GluGly: 2.867 ± 0.03
1.498GluHis: 1.498 ± 0.019
4.27GluIle: 4.27 ± 0.045
5.191GluLys: 5.191 ± 0.054
5.531GluLeu: 5.531 ± 0.046
1.592GluMet: 1.592 ± 0.017
3.902GluAsn: 3.902 ± 0.033
2.284GluPro: 2.284 ± 0.032
2.701GluGln: 2.701 ± 0.028
4.251GluArg: 4.251 ± 0.042
4.6GluSer: 4.6 ± 0.037
3.921GluThr: 3.921 ± 0.039
3.501GluVal: 3.501 ± 0.034
0.663GluTrp: 0.663 ± 0.01
1.972GluTyr: 1.972 ± 0.019
0.001GluXaa: 0.001 ± 0.0
Phe
2.157PheAla: 2.157 ± 0.023
0.864PheCys: 0.864 ± 0.012
2.01PheAsp: 2.01 ± 0.021
2.116PheGlu: 2.116 ± 0.024
1.597PhePhe: 1.597 ± 0.021
2.078PheGly: 2.078 ± 0.023
1.028PheHis: 1.028 ± 0.014
2.24PheIle: 2.24 ± 0.023
2.023PheLys: 2.023 ± 0.017
3.718PheLeu: 3.718 ± 0.034
0.82PheMet: 0.82 ± 0.011
1.8PheAsn: 1.8 ± 0.018
1.698PhePro: 1.698 ± 0.021
1.387PheGln: 1.387 ± 0.015
1.946PheArg: 1.946 ± 0.02
2.971PheSer: 2.971 ± 0.025
2.141PheThr: 2.141 ± 0.019
2.417PheVal: 2.417 ± 0.023
0.418PheTrp: 0.418 ± 0.009
1.351PheTyr: 1.351 ± 0.017
0.001PheXaa: 0.001 ± 0.0
Gly
3.002GlyAla: 3.002 ± 0.03
1.043GlyCys: 1.043 ± 0.02
2.716GlyAsp: 2.716 ± 0.027
3.02GlyGlu: 3.02 ± 0.033
2.022GlyPhe: 2.022 ± 0.025
4.067GlyGly: 4.067 ± 0.057
1.357GlyHis: 1.357 ± 0.02
3.247GlyIle: 3.247 ± 0.031
3.251GlyLys: 3.251 ± 0.028
4.303GlyLeu: 4.303 ± 0.037
1.183GlyMet: 1.183 ± 0.018
2.657GlyAsn: 2.657 ± 0.025
2.289GlyPro: 2.289 ± 0.035
1.927GlyGln: 1.927 ± 0.022
3.196GlyArg: 3.196 ± 0.031
4.345GlySer: 4.345 ± 0.038
3.223GlyThr: 3.223 ± 0.03
3.099GlyVal: 3.099 ± 0.031
0.65GlyTrp: 0.65 ± 0.011
1.89GlyTyr: 1.89 ± 0.025
0.003GlyXaa: 0.003 ± 0.001
His
1.428HisAla: 1.428 ± 0.017
0.61HisCys: 0.61 ± 0.011
1.16HisAsp: 1.16 ± 0.014
1.425HisGlu: 1.425 ± 0.019
1.015HisPhe: 1.015 ± 0.013
1.375HisGly: 1.375 ± 0.016
1.112HisHis: 1.112 ± 0.028
1.519HisIle: 1.519 ± 0.018
1.361HisLys: 1.361 ± 0.017
2.373HisLeu: 2.373 ± 0.025
0.594HisMet: 0.594 ± 0.01
1.199HisAsn: 1.199 ± 0.014
1.383HisPro: 1.383 ± 0.02
1.098HisGln: 1.098 ± 0.017
1.605HisArg: 1.605 ± 0.016
1.985HisSer: 1.985 ± 0.021
1.412HisThr: 1.412 ± 0.017
1.621HisVal: 1.621 ± 0.019
0.289HisTrp: 0.289 ± 0.007
0.9HisTyr: 0.9 ± 0.012
0.0HisXaa: 0.0 ± 0.0
Ile
3.837IleAla: 3.837 ± 0.029
1.376IleCys: 1.376 ± 0.022
3.381IleAsp: 3.381 ± 0.028
3.913IleGlu: 3.913 ± 0.041
2.543IlePhe: 2.543 ± 0.027
3.044IleGly: 3.044 ± 0.027
1.476IleHis: 1.476 ± 0.016
3.932IleIle: 3.932 ± 0.043
3.852IleLys: 3.852 ± 0.037
5.833IleLeu: 5.833 ± 0.046
1.408IleMet: 1.408 ± 0.018
3.254IleAsn: 3.254 ± 0.028
3.006IlePro: 3.006 ± 0.026
2.328IleGln: 2.328 ± 0.02
3.177IleArg: 3.177 ± 0.025
4.872IleSer: 4.872 ± 0.036
3.591IleThr: 3.591 ± 0.034
3.869IleVal: 3.869 ± 0.028
0.625IleTrp: 0.625 ± 0.011
2.016IleTyr: 2.016 ± 0.022
0.001IleXaa: 0.001 ± 0.0
Lys
3.263LysAla: 3.263 ± 0.03
1.269LysCys: 1.269 ± 0.023
3.543LysAsp: 3.543 ± 0.04
4.885LysGlu: 4.885 ± 0.053
2.143LysPhe: 2.143 ± 0.021
2.569LysGly: 2.569 ± 0.029
1.572LysHis: 1.572 ± 0.018
4.204LysIle: 4.204 ± 0.038
5.4LysLys: 5.4 ± 0.063
5.78LysLeu: 5.78 ± 0.044
1.531LysMet: 1.531 ± 0.015
3.47LysAsn: 3.47 ± 0.034
2.712LysPro: 2.712 ± 0.043
2.661LysGln: 2.661 ± 0.025
4.12LysArg: 4.12 ± 0.036
4.708LysSer: 4.708 ± 0.041
3.633LysThr: 3.633 ± 0.029
3.34LysVal: 3.34 ± 0.029
0.674LysTrp: 0.674 ± 0.012
2.164LysTyr: 2.164 ± 0.022
0.001LysXaa: 0.001 ± 0.0
Leu
5.701LeuAla: 5.701 ± 0.043
1.878LeuCys: 1.878 ± 0.021
4.664LeuAsp: 4.664 ± 0.035
5.874LeuGlu: 5.874 ± 0.05
3.253LeuPhe: 3.253 ± 0.031
4.27LeuGly: 4.27 ± 0.035
2.529LeuHis: 2.529 ± 0.022
5.027LeuIle: 5.027 ± 0.036
5.893LeuLys: 5.893 ± 0.042
8.9LeuLeu: 8.9 ± 0.064
2.035LeuMet: 2.035 ± 0.02
4.338LeuAsn: 4.338 ± 0.027
4.796LeuPro: 4.796 ± 0.03
4.403LeuGln: 4.403 ± 0.032
5.543LeuArg: 5.543 ± 0.036
7.371LeuSer: 7.371 ± 0.045
5.137LeuThr: 5.137 ± 0.029
4.859LeuVal: 4.859 ± 0.035
0.915LeuTrp: 0.915 ± 0.013
2.847LeuTyr: 2.847 ± 0.027
0.003LeuXaa: 0.003 ± 0.001
Met
1.474MetAla: 1.474 ± 0.017
0.457MetCys: 0.457 ± 0.009
1.278MetAsp: 1.278 ± 0.015
1.649MetGlu: 1.649 ± 0.017
0.836MetPhe: 0.836 ± 0.012
1.075MetGly: 1.075 ± 0.016
0.59MetHis: 0.59 ± 0.01
1.356MetIle: 1.356 ± 0.017
1.566MetLys: 1.566 ± 0.015
2.099MetLeu: 2.099 ± 0.019
0.62MetMet: 0.62 ± 0.01
1.128MetAsn: 1.128 ± 0.013
1.112MetPro: 1.112 ± 0.015
1.082MetGln: 1.082 ± 0.016
1.301MetArg: 1.301 ± 0.015
1.836MetSer: 1.836 ± 0.018
1.333MetThr: 1.333 ± 0.015
1.197MetVal: 1.197 ± 0.014
0.243MetTrp: 0.243 ± 0.006
0.755MetTyr: 0.755 ± 0.011
0.0MetXaa: 0.0 ± 0.0
Asn
3.019AsnAla: 3.019 ± 0.023
1.001AsnCys: 1.001 ± 0.016
2.882AsnAsp: 2.882 ± 0.025
3.368AsnGlu: 3.368 ± 0.03
1.959AsnPhe: 1.959 ± 0.02
2.823AsnGly: 2.823 ± 0.025
1.192AsnHis: 1.192 ± 0.018
3.622AsnIle: 3.622 ± 0.032
3.195AsnLys: 3.195 ± 0.033
4.541AsnLeu: 4.541 ± 0.029
1.224AsnMet: 1.224 ± 0.016
3.315AsnAsn: 3.315 ± 0.034
2.193AsnPro: 2.193 ± 0.034
1.867AsnGln: 1.867 ± 0.021
2.614AsnArg: 2.614 ± 0.025
4.077AsnSer: 4.077 ± 0.031
2.961AsnThr: 2.961 ± 0.026
3.552AsnVal: 3.552 ± 0.026
0.515AsnTrp: 0.515 ± 0.011
1.722AsnTyr: 1.722 ± 0.017
0.001AsnXaa: 0.001 ± 0.0
Pro
2.889ProAla: 2.889 ± 0.025
0.876ProCys: 0.876 ± 0.041
2.344ProAsp: 2.344 ± 0.02
3.006ProGlu: 3.006 ± 0.037
1.651ProPhe: 1.651 ± 0.019
2.795ProGly: 2.795 ± 0.074
1.188ProHis: 1.188 ± 0.016
2.709ProIle: 2.709 ± 0.026
2.594ProLys: 2.594 ± 0.031
4.165ProLeu: 4.165 ± 0.029
1.002ProMet: 1.002 ± 0.013
2.202ProAsn: 2.202 ± 0.027
4.033ProPro: 4.033 ± 0.061
1.973ProGln: 1.973 ± 0.026
2.879ProArg: 2.879 ± 0.03
4.312ProSer: 4.312 ± 0.045
3.109ProThr: 3.109 ± 0.035
3.026ProVal: 3.026 ± 0.027
0.491ProTrp: 0.491 ± 0.009
1.496ProTyr: 1.496 ± 0.018
0.002ProXaa: 0.002 ± 0.001
Gln
2.296GlnAla: 2.296 ± 0.024
0.822GlnCys: 0.822 ± 0.019
1.934GlnAsp: 1.934 ± 0.019
2.85GlnGlu: 2.85 ± 0.028
1.363GlnPhe: 1.363 ± 0.013
1.736GlnGly: 1.736 ± 0.024
1.212GlnHis: 1.212 ± 0.015
2.363GlnIle: 2.363 ± 0.022
2.544GlnLys: 2.544 ± 0.029
3.776GlnLeu: 3.776 ± 0.033
0.977GlnMet: 0.977 ± 0.014
2.237GlnAsn: 2.237 ± 0.023
1.951GlnPro: 1.951 ± 0.027
3.284GlnGln: 3.284 ± 0.074
2.59GlnArg: 2.59 ± 0.024
3.069GlnSer: 3.069 ± 0.029
2.3GlnThr: 2.3 ± 0.025
2.157GlnVal: 2.157 ± 0.021
0.456GlnTrp: 0.456 ± 0.008
1.293GlnTyr: 1.293 ± 0.017
0.001GlnXaa: 0.001 ± 0.0
Arg
3.351ArgAla: 3.351 ± 0.031
1.253ArgCys: 1.253 ± 0.02
3.136ArgAsp: 3.136 ± 0.025
4.058ArgGlu: 4.058 ± 0.038
2.111ArgPhe: 2.111 ± 0.022
3.193ArgGly: 3.193 ± 0.038
1.66ArgHis: 1.66 ± 0.018
3.414ArgIle: 3.414 ± 0.025
4.133ArgLys: 4.133 ± 0.029
5.227ArgLeu: 5.227 ± 0.036
1.315ArgMet: 1.315 ± 0.015
3.073ArgAsn: 3.073 ± 0.027
2.623ArgPro: 2.623 ± 0.034
2.43ArgGln: 2.43 ± 0.023
4.856ArgArg: 4.856 ± 0.041
4.702ArgSer: 4.702 ± 0.043
3.195ArgThr: 3.195 ± 0.027
3.167ArgVal: 3.167 ± 0.026
0.662ArgTrp: 0.662 ± 0.012
1.932ArgTyr: 1.932 ± 0.023
0.002ArgXaa: 0.002 ± 0.001
Ser
4.62SerAla: 4.62 ± 0.034
1.58SerCys: 1.58 ± 0.029
4.31SerAsp: 4.31 ± 0.034
4.717SerGlu: 4.717 ± 0.041
2.924SerPhe: 2.924 ± 0.022
4.521SerGly: 4.521 ± 0.04
1.942SerHis: 1.942 ± 0.022
4.633SerIle: 4.633 ± 0.031
4.675SerLys: 4.675 ± 0.037
7.2SerLeu: 7.2 ± 0.049
1.788SerMet: 1.788 ± 0.019
4.254SerAsn: 4.254 ± 0.035
4.42SerPro: 4.42 ± 0.05
3.128SerGln: 3.128 ± 0.027
4.751SerArg: 4.751 ± 0.042
8.649SerSer: 8.649 ± 0.077
5.446SerThr: 5.446 ± 0.041
4.76SerVal: 4.76 ± 0.028
0.844SerTrp: 0.844 ± 0.013
2.346SerTyr: 2.346 ± 0.022
0.001SerXaa: 0.001 ± 0.0
Thr
3.795ThrAla: 3.795 ± 0.03
1.274ThrCys: 1.274 ± 0.023
3.011ThrAsp: 3.011 ± 0.026
3.724ThrGlu: 3.724 ± 0.045
2.235ThrPhe: 2.235 ± 0.021
3.235ThrGly: 3.235 ± 0.026
1.338ThrHis: 1.338 ± 0.019
3.743ThrIle: 3.743 ± 0.031
3.497ThrLys: 3.497 ± 0.037
5.381ThrLeu: 5.381 ± 0.033
1.395ThrMet: 1.395 ± 0.018
2.982ThrAsn: 2.982 ± 0.025
3.231ThrPro: 3.231 ± 0.033
2.139ThrGln: 2.139 ± 0.022
3.187ThrArg: 3.187 ± 0.026
5.412ThrSer: 5.412 ± 0.041
4.476ThrThr: 4.476 ± 0.067
3.903ThrVal: 3.903 ± 0.033
0.651ThrTrp: 0.651 ± 0.01
1.806ThrTyr: 1.806 ± 0.017
0.002ThrXaa: 0.002 ± 0.001
Val
3.974ValAla: 3.974 ± 0.029
1.369ValCys: 1.369 ± 0.022
3.18ValAsp: 3.18 ± 0.02
3.742ValGlu: 3.742 ± 0.032
2.239ValPhe: 2.239 ± 0.023
2.943ValGly: 2.943 ± 0.028
1.505ValHis: 1.505 ± 0.017
3.674ValIle: 3.674 ± 0.027
3.623ValLys: 3.623 ± 0.032
5.329ValLeu: 5.329 ± 0.037
1.341ValMet: 1.341 ± 0.016
2.863ValAsn: 2.863 ± 0.028
3.159ValPro: 3.159 ± 0.027
2.455ValGln: 2.455 ± 0.021
3.212ValArg: 3.212 ± 0.025
4.688ValSer: 4.688 ± 0.029
3.923ValThr: 3.923 ± 0.04
3.707ValVal: 3.707 ± 0.033
0.632ValTrp: 0.632 ± 0.012
1.872ValTyr: 1.872 ± 0.02
0.001ValXaa: 0.001 ± 0.0
Trp
0.546TrpAla: 0.546 ± 0.011
0.236TrpCys: 0.236 ± 0.006
0.58TrpAsp: 0.58 ± 0.011
0.603TrpGlu: 0.603 ± 0.009
0.425TrpPhe: 0.425 ± 0.01
0.516TrpGly: 0.516 ± 0.012
0.285TrpHis: 0.285 ± 0.006
0.71TrpIle: 0.71 ± 0.012
0.744TrpLys: 0.744 ± 0.015
1.095TrpLeu: 1.095 ± 0.014
0.282TrpMet: 0.282 ± 0.007
0.594TrpAsn: 0.594 ± 0.009
0.428TrpPro: 0.428 ± 0.01
0.47TrpGln: 0.47 ± 0.01
0.731TrpArg: 0.731 ± 0.012
0.815TrpSer: 0.815 ± 0.013
0.61TrpThr: 0.61 ± 0.009
0.496TrpVal: 0.496 ± 0.01
0.188TrpTrp: 0.188 ± 0.006
0.376TrpTyr: 0.376 ± 0.009
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.79TyrAla: 1.79 ± 0.018
0.744TyrCys: 0.744 ± 0.012
1.732TyrAsp: 1.732 ± 0.019
1.913TyrGlu: 1.913 ± 0.019
1.428TyrPhe: 1.428 ± 0.018
1.775TyrGly: 1.775 ± 0.021
0.893TyrHis: 0.893 ± 0.011
2.041TyrIle: 2.041 ± 0.02
1.936TyrLys: 1.936 ± 0.022
2.948TyrLeu: 2.948 ± 0.023
0.76TyrMet: 0.76 ± 0.011
1.73TyrAsn: 1.73 ± 0.019
1.477TyrPro: 1.477 ± 0.021
1.242TyrGln: 1.242 ± 0.016
1.846TyrArg: 1.846 ± 0.021
2.377TyrSer: 2.377 ± 0.02
1.813TyrThr: 1.813 ± 0.02
2.004TyrVal: 2.004 ± 0.021
0.354TyrTrp: 0.354 ± 0.009
1.265TyrTyr: 1.265 ± 0.017
0.002TyrXaa: 0.002 ± 0.001
Xaa
0.003XaaAla: 0.003 ± 0.001
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.002XaaGlu: 0.002 ± 0.0
0.001XaaPhe: 0.001 ± 0.0
0.001XaaGly: 0.001 ± 0.0
0.001XaaHis: 0.001 ± 0.0
0.001XaaIle: 0.001 ± 0.0
0.002XaaLys: 0.002 ± 0.001
0.001XaaLeu: 0.001 ± 0.0
0.001XaaMet: 0.001 ± 0.0
0.001XaaAsn: 0.001 ± 0.0
0.002XaaPro: 0.002 ± 0.001
0.001XaaGln: 0.001 ± 0.0
0.003XaaArg: 0.003 ± 0.001
0.003XaaSer: 0.003 ± 0.001
0.001XaaThr: 0.001 ± 0.0
0.001XaaVal: 0.001 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.001XaaTyr: 0.001 ± 0.0
1.619XaaXaa: 1.619 ± 0.231
Statistics based on 14302 proteins (6592638 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski