Amino acid dipepetide frequency for Pedilanthus leaf curl virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.608AlaAla: 7.608 ± 3.279
1.691AlaCys: 1.691 ± 1.121
0.845AlaAsp: 0.845 ± 0.775
0.845AlaGlu: 0.845 ± 0.65
0.845AlaPhe: 0.845 ± 0.978
1.691AlaGly: 1.691 ± 0.784
2.536AlaHis: 2.536 ± 1.129
0.845AlaIle: 0.845 ± 0.65
4.227AlaLys: 4.227 ± 1.26
7.608AlaLeu: 7.608 ± 2.395
0.0AlaMet: 0.0 ± 0.0
3.381AlaAsn: 3.381 ± 1.346
4.227AlaPro: 4.227 ± 1.26
5.072AlaGln: 5.072 ± 2.377
4.227AlaArg: 4.227 ± 2.331
5.072AlaSer: 5.072 ± 1.299
4.227AlaThr: 4.227 ± 2.083
2.536AlaVal: 2.536 ± 1.547
1.691AlaTrp: 1.691 ± 0.784
0.845AlaTyr: 0.845 ± 0.65
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.691CysCys: 1.691 ± 1.997
0.0CysAsp: 0.0 ± 0.0
0.845CysGlu: 0.845 ± 0.775
0.845CysPhe: 0.845 ± 0.978
1.691CysGly: 1.691 ± 0.885
0.845CysHis: 0.845 ± 0.863
0.845CysIle: 0.845 ± 1.067
0.845CysLys: 0.845 ± 0.775
0.0CysLeu: 0.0 ± 0.0
1.691CysMet: 1.691 ± 1.015
0.845CysAsn: 0.845 ± 0.65
2.536CysPro: 2.536 ± 2.123
0.845CysGln: 0.845 ± 0.65
0.845CysArg: 0.845 ± 0.65
4.227CysSer: 4.227 ± 1.765
0.845CysThr: 0.845 ± 0.775
1.691CysVal: 1.691 ± 1.551
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
1.691AspAla: 1.691 ± 1.3
0.0AspCys: 0.0 ± 0.0
1.691AspAsp: 1.691 ± 0.885
1.691AspGlu: 1.691 ± 0.784
0.845AspPhe: 0.845 ± 0.775
1.691AspGly: 1.691 ± 1.3
0.845AspHis: 0.845 ± 0.978
2.536AspIle: 2.536 ± 1.495
0.845AspLys: 0.845 ± 0.775
5.917AspLeu: 5.917 ± 2.156
0.0AspMet: 0.0 ± 0.0
3.381AspAsn: 3.381 ± 1.473
1.691AspPro: 1.691 ± 1.013
1.691AspGln: 1.691 ± 1.3
2.536AspArg: 2.536 ± 1.418
5.917AspSer: 5.917 ± 1.427
3.381AspThr: 3.381 ± 1.735
5.072AspVal: 5.072 ± 1.927
2.536AspTrp: 2.536 ± 1.29
0.845AspTyr: 0.845 ± 0.65
0.0AspXaa: 0.0 ± 0.0
Glu
4.227GluAla: 4.227 ± 1.645
0.0GluCys: 0.0 ± 0.0
0.845GluAsp: 0.845 ± 0.935
3.381GluGlu: 3.381 ± 1.842
4.227GluPhe: 4.227 ± 2.487
5.917GluGly: 5.917 ± 2.1
1.691GluHis: 1.691 ± 1.956
0.845GluIle: 0.845 ± 0.978
1.691GluLys: 1.691 ± 1.3
3.381GluLeu: 3.381 ± 1.542
0.0GluMet: 0.0 ± 0.796
5.072GluAsn: 5.072 ± 1.997
3.381GluPro: 3.381 ± 1.042
2.536GluGln: 2.536 ± 2.002
0.0GluArg: 0.0 ± 0.0
3.381GluSer: 3.381 ± 1.617
1.691GluThr: 1.691 ± 1.249
2.536GluVal: 2.536 ± 1.214
0.845GluTrp: 0.845 ± 0.863
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.845PheAla: 0.845 ± 1.067
0.845PheCys: 0.845 ± 0.775
3.381PheAsp: 3.381 ± 1.568
2.536PheGlu: 2.536 ± 0.963
2.536PhePhe: 2.536 ± 1.214
0.845PheGly: 0.845 ± 0.775
3.381PheHis: 3.381 ± 1.903
4.227PheIle: 4.227 ± 1.016
2.536PheLys: 2.536 ± 1.911
7.608PheLeu: 7.608 ± 3.151
0.845PheMet: 0.845 ± 0.65
2.536PheAsn: 2.536 ± 1.816
1.691PhePro: 1.691 ± 1.277
2.536PheGln: 2.536 ± 1.29
3.381PheArg: 3.381 ± 2.154
0.845PheSer: 0.845 ± 0.65
2.536PheThr: 2.536 ± 1.142
0.0PheVal: 0.0 ± 0.0
0.0PheTrp: 0.0 ± 0.0
0.845PheTyr: 0.845 ± 0.775
0.0PheXaa: 0.0 ± 0.0
Gly
1.691GlyAla: 1.691 ± 1.3
1.691GlyCys: 1.691 ± 1.121
5.917GlyAsp: 5.917 ± 2.019
5.072GlyGlu: 5.072 ± 1.045
1.691GlyPhe: 1.691 ± 1.277
2.536GlyGly: 2.536 ± 1.214
0.845GlyHis: 0.845 ± 0.65
1.691GlyIle: 1.691 ± 1.04
5.917GlyLys: 5.917 ± 2.918
2.536GlyLeu: 2.536 ± 1.425
0.0GlyMet: 0.0 ± 0.0
0.845GlyAsn: 0.845 ± 0.935
3.381GlyPro: 3.381 ± 1.783
2.536GlyGln: 2.536 ± 1.093
1.691GlyArg: 1.691 ± 1.04
1.691GlySer: 1.691 ± 1.3
3.381GlyThr: 3.381 ± 1.971
1.691GlyVal: 1.691 ± 1.956
0.0GlyTrp: 0.0 ± 0.0
0.845GlyTyr: 0.845 ± 0.998
0.0GlyXaa: 0.0 ± 0.0
His
1.691HisAla: 1.691 ± 1.144
2.536HisCys: 2.536 ± 1.937
0.845HisAsp: 0.845 ± 0.775
3.381HisGlu: 3.381 ± 1.547
2.536HisPhe: 2.536 ± 1.379
1.691HisGly: 1.691 ± 1.277
3.381HisHis: 3.381 ± 2.702
2.536HisIle: 2.536 ± 1.427
0.845HisLys: 0.845 ± 0.978
1.691HisLeu: 1.691 ± 1.3
0.0HisMet: 0.0 ± 0.0
5.072HisAsn: 5.072 ± 2.215
0.845HisPro: 0.845 ± 0.65
0.845HisGln: 0.845 ± 0.998
3.381HisArg: 3.381 ± 2.242
2.536HisSer: 2.536 ± 1.425
0.845HisThr: 0.845 ± 0.775
3.381HisVal: 3.381 ± 2.223
0.0HisTrp: 0.0 ± 0.0
0.845HisTyr: 0.845 ± 0.65
0.0HisXaa: 0.0 ± 0.0
Ile
0.845IleAla: 0.845 ± 0.863
0.845IleCys: 0.845 ± 0.65
1.691IleAsp: 1.691 ± 1.3
0.0IleGlu: 0.0 ± 0.0
2.536IlePhe: 2.536 ± 1.443
0.845IleGly: 0.845 ± 0.775
1.691IleHis: 1.691 ± 1.551
5.072IleIle: 5.072 ± 3.319
5.917IleLys: 5.917 ± 1.314
4.227IleLeu: 4.227 ± 5.335
0.0IleMet: 0.0 ± 0.0
1.691IleAsn: 1.691 ± 1.551
2.536IlePro: 2.536 ± 1.219
5.072IleGln: 5.072 ± 2.021
5.072IleArg: 5.072 ± 3.078
4.227IleSer: 4.227 ± 2.068
5.072IleThr: 5.072 ± 3.104
1.691IleVal: 1.691 ± 0.784
3.381IleTrp: 3.381 ± 1.997
3.381IleTyr: 3.381 ± 0.926
0.0IleXaa: 0.0 ± 0.0
Lys
4.227LysAla: 4.227 ± 1.709
2.536LysCys: 2.536 ± 1.432
1.691LysAsp: 1.691 ± 1.3
4.227LysGlu: 4.227 ± 2.393
1.691LysPhe: 1.691 ± 0.997
2.536LysGly: 2.536 ± 1.623
1.691LysHis: 1.691 ± 1.045
5.072LysIle: 5.072 ± 1.433
2.536LysLys: 2.536 ± 0.941
0.845LysLeu: 0.845 ± 1.067
0.845LysMet: 0.845 ± 0.935
5.917LysAsn: 5.917 ± 2.087
2.536LysPro: 2.536 ± 1.418
0.0LysGln: 0.0 ± 0.0
2.536LysArg: 2.536 ± 1.418
6.762LysSer: 6.762 ± 2.208
2.536LysThr: 2.536 ± 0.842
4.227LysVal: 4.227 ± 2.167
0.845LysTrp: 0.845 ± 0.775
5.072LysTyr: 5.072 ± 1.464
0.0LysXaa: 0.0 ± 0.0
Leu
5.072LeuAla: 5.072 ± 2.198
1.691LeuCys: 1.691 ± 1.3
5.072LeuAsp: 5.072 ± 2.368
5.072LeuGlu: 5.072 ± 2.524
1.691LeuPhe: 1.691 ± 1.385
5.072LeuGly: 5.072 ± 1.68
2.536LeuHis: 2.536 ± 2.009
5.917LeuIle: 5.917 ± 3.125
5.072LeuLys: 5.072 ± 1.433
3.381LeuLeu: 3.381 ± 2.588
2.536LeuMet: 2.536 ± 1.195
3.381LeuAsn: 3.381 ± 1.181
1.691LeuPro: 1.691 ± 1.727
3.381LeuGln: 3.381 ± 1.409
6.762LeuArg: 6.762 ± 2.594
4.227LeuSer: 4.227 ± 2.123
4.227LeuThr: 4.227 ± 1.889
5.917LeuVal: 5.917 ± 3.118
0.845LeuTrp: 0.845 ± 0.978
3.381LeuTyr: 3.381 ± 1.106
0.0LeuXaa: 0.0 ± 0.0
Met
1.691MetAla: 1.691 ± 0.784
0.845MetCys: 0.845 ± 0.775
1.691MetAsp: 1.691 ± 0.997
1.691MetGlu: 1.691 ± 1.027
2.536MetPhe: 2.536 ± 1.724
2.536MetGly: 2.536 ± 1.162
0.845MetHis: 0.845 ± 1.067
0.845MetIle: 0.845 ± 1.067
0.845MetLys: 0.845 ± 0.935
1.691MetLeu: 1.691 ± 1.144
0.0MetMet: 0.0 ± 0.0
1.691MetAsn: 1.691 ± 0.997
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.845MetArg: 0.845 ± 0.863
0.845MetSer: 0.845 ± 0.775
0.845MetThr: 0.845 ± 0.978
0.0MetVal: 0.0 ± 0.0
1.691MetTrp: 1.691 ± 1.013
1.691MetTyr: 1.691 ± 1.551
0.0MetXaa: 0.0 ± 0.0
Asn
3.381AsnAla: 3.381 ± 1.783
0.0AsnCys: 0.0 ± 0.0
0.845AsnAsp: 0.845 ± 0.65
2.536AsnGlu: 2.536 ± 0.963
1.691AsnPhe: 1.691 ± 0.784
1.691AsnGly: 1.691 ± 1.04
4.227AsnHis: 4.227 ± 1.709
3.381AsnIle: 3.381 ± 1.135
1.691AsnLys: 1.691 ± 1.045
7.608AsnLeu: 7.608 ± 2.809
2.536AsnMet: 2.536 ± 1.571
1.691AsnAsn: 1.691 ± 0.997
2.536AsnPro: 2.536 ± 0.842
4.227AsnGln: 4.227 ± 1.726
3.381AsnArg: 3.381 ± 1.636
4.227AsnSer: 4.227 ± 1.219
2.536AsnThr: 2.536 ± 1.162
4.227AsnVal: 4.227 ± 1.726
1.691AsnTrp: 1.691 ± 1.045
2.536AsnTyr: 2.536 ± 0.963
0.0AsnXaa: 0.0 ± 0.0
Pro
1.691ProAla: 1.691 ± 0.784
2.536ProCys: 2.536 ± 1.361
2.536ProAsp: 2.536 ± 1.361
2.536ProGlu: 2.536 ± 1.129
2.536ProPhe: 2.536 ± 1.435
1.691ProGly: 1.691 ± 1.027
4.227ProHis: 4.227 ± 1.76
4.227ProIle: 4.227 ± 1.821
4.227ProLys: 4.227 ± 3.251
4.227ProLeu: 4.227 ± 1.393
1.691ProMet: 1.691 ± 0.784
2.536ProAsn: 2.536 ± 1.29
3.381ProPro: 3.381 ± 1.483
3.381ProGln: 3.381 ± 2.103
3.381ProArg: 3.381 ± 1.81
5.072ProSer: 5.072 ± 2.755
3.381ProThr: 3.381 ± 1.99
4.227ProVal: 4.227 ± 2.156
0.0ProTrp: 0.0 ± 0.0
0.845ProTyr: 0.845 ± 0.775
0.0ProXaa: 0.0 ± 0.0
Gln
5.917GlnAla: 5.917 ± 1.674
0.0GlnCys: 0.0 ± 0.0
4.227GlnAsp: 4.227 ± 2.142
2.536GlnGlu: 2.536 ± 1.093
2.536GlnPhe: 2.536 ± 1.432
0.845GlnGly: 0.845 ± 0.65
2.536GlnHis: 2.536 ± 1.402
4.227GlnIle: 4.227 ± 2.555
1.691GlnLys: 1.691 ± 1.997
1.691GlnLeu: 1.691 ± 1.997
0.845GlnMet: 0.845 ± 0.863
4.227GlnAsn: 4.227 ± 2.268
4.227GlnPro: 4.227 ± 2.22
2.536GlnGln: 2.536 ± 0.941
3.381GlnArg: 3.381 ± 2.055
5.917GlnSer: 5.917 ± 1.186
1.691GlnThr: 1.691 ± 0.885
3.381GlnVal: 3.381 ± 0.926
0.0GlnTrp: 0.0 ± 0.0
0.845GlnTyr: 0.845 ± 0.775
0.0GlnXaa: 0.0 ± 0.0
Arg
4.227ArgAla: 4.227 ± 1.548
1.691ArgCys: 1.691 ± 1.997
3.381ArgAsp: 3.381 ± 1.426
2.536ArgGlu: 2.536 ± 1.162
4.227ArgPhe: 4.227 ± 1.063
3.381ArgGly: 3.381 ± 1.48
2.536ArgHis: 2.536 ± 1.361
4.227ArgIle: 4.227 ± 1.213
2.536ArgLys: 2.536 ± 1.495
4.227ArgLeu: 4.227 ± 2.224
1.691ArgMet: 1.691 ± 1.551
0.845ArgAsn: 0.845 ± 0.998
5.917ArgPro: 5.917 ± 1.703
0.845ArgGln: 0.845 ± 0.998
7.608ArgArg: 7.608 ± 3.716
4.227ArgSer: 4.227 ± 1.81
4.227ArgThr: 4.227 ± 2.166
5.072ArgVal: 5.072 ± 1.882
0.0ArgTrp: 0.0 ± 0.0
1.691ArgTyr: 1.691 ± 1.144
0.0ArgXaa: 0.0 ± 0.0
Ser
5.072SerAla: 5.072 ± 3.2
1.691SerCys: 1.691 ± 1.045
3.381SerAsp: 3.381 ± 1.164
1.691SerGlu: 1.691 ± 0.784
4.227SerPhe: 4.227 ± 1.238
0.845SerGly: 0.845 ± 0.65
0.0SerHis: 0.0 ± 0.0
3.381SerIle: 3.381 ± 2.038
6.762SerLys: 6.762 ± 2.397
3.381SerLeu: 3.381 ± 1.378
2.536SerMet: 2.536 ± 1.883
5.072SerAsn: 5.072 ± 2.028
7.608SerPro: 7.608 ± 1.609
6.762SerGln: 6.762 ± 2.627
6.762SerArg: 6.762 ± 2.047
14.37SerSer: 14.37 ± 5.417
6.762SerThr: 6.762 ± 3.234
4.227SerVal: 4.227 ± 2.429
0.0SerTrp: 0.0 ± 0.0
2.536SerTyr: 2.536 ± 1.29
0.0SerXaa: 0.0 ± 0.0
Thr
2.536ThrAla: 2.536 ± 1.236
0.845ThrCys: 0.845 ± 0.935
0.0ThrAsp: 0.0 ± 0.0
2.536ThrGlu: 2.536 ± 1.509
1.691ThrPhe: 1.691 ± 1.027
6.762ThrGly: 6.762 ± 2.527
3.381ThrHis: 3.381 ± 2.242
0.845ThrIle: 0.845 ± 0.863
3.381ThrLys: 3.381 ± 1.568
5.072ThrLeu: 5.072 ± 1.789
1.691ThrMet: 1.691 ± 1.045
1.691ThrAsn: 1.691 ± 1.551
5.072ThrPro: 5.072 ± 1.789
3.381ThrGln: 3.381 ± 2.069
2.536ThrArg: 2.536 ± 0.941
3.381ThrSer: 3.381 ± 2.154
0.845ThrThr: 0.845 ± 0.935
5.072ThrVal: 5.072 ± 2.006
0.0ThrTrp: 0.0 ± 0.0
1.691ThrTyr: 1.691 ± 1.013
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.0ValCys: 0.0 ± 0.0
4.227ValAsp: 4.227 ± 1.016
1.691ValGlu: 1.691 ± 1.997
2.536ValPhe: 2.536 ± 1.816
1.691ValGly: 1.691 ± 1.121
1.691ValHis: 1.691 ± 1.144
4.227ValIle: 4.227 ± 1.768
5.072ValLys: 5.072 ± 2.056
6.762ValLeu: 6.762 ± 2.508
1.691ValMet: 1.691 ± 1.551
3.381ValAsn: 3.381 ± 1.135
3.381ValPro: 3.381 ± 1.09
5.917ValGln: 5.917 ± 2.132
3.381ValArg: 3.381 ± 2.162
5.917ValSer: 5.917 ± 1.938
3.381ValThr: 3.381 ± 3.102
3.381ValVal: 3.381 ± 1.648
0.845ValTrp: 0.845 ± 0.65
5.072ValTyr: 5.072 ± 1.821
0.0ValXaa: 0.0 ± 0.0
Trp
3.381TrpAla: 3.381 ± 1.783
0.0TrpCys: 0.0 ± 0.0
0.845TrpAsp: 0.845 ± 0.998
0.845TrpGlu: 0.845 ± 0.978
0.0TrpPhe: 0.0 ± 0.0
0.845TrpGly: 0.845 ± 0.65
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
1.691TrpMet: 1.691 ± 0.997
0.845TrpAsn: 0.845 ± 0.978
0.0TrpPro: 0.0 ± 0.0
0.845TrpGln: 0.845 ± 0.65
1.691TrpArg: 1.691 ± 1.228
1.691TrpSer: 1.691 ± 1.385
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
1.691TrpTyr: 1.691 ± 0.784
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.227TyrAla: 4.227 ± 2.156
0.0TyrCys: 0.0 ± 0.0
1.691TyrAsp: 1.691 ± 1.144
0.845TyrGlu: 0.845 ± 0.775
2.536TyrPhe: 2.536 ± 1.236
0.845TyrGly: 0.845 ± 0.65
0.0TyrHis: 0.0 ± 0.0
0.845TyrIle: 0.845 ± 0.65
1.691TyrLys: 1.691 ± 1.3
5.072TyrLeu: 5.072 ± 1.725
1.691TyrMet: 1.691 ± 0.945
2.536TyrAsn: 2.536 ± 0.963
1.691TyrPro: 1.691 ± 1.027
0.845TyrGln: 0.845 ± 0.775
1.691TyrArg: 1.691 ± 1.551
2.536TyrSer: 2.536 ± 1.379
0.0TyrThr: 0.0 ± 0.0
5.917TyrVal: 5.917 ± 1.611
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1184 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski