Amino acid dipepetide frequency for Sclerotinia sclerotiorum mycoreovirus 4

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.146AlaAla: 4.146 ± 0.962
1.684AlaCys: 1.684 ± 0.482
4.276AlaAsp: 4.276 ± 0.508
2.203AlaGlu: 2.203 ± 0.651
2.98AlaPhe: 2.98 ± 0.682
2.203AlaGly: 2.203 ± 0.515
2.073AlaHis: 2.073 ± 0.367
3.498AlaIle: 3.498 ± 0.654
2.203AlaLys: 2.203 ± 0.578
4.924AlaLeu: 4.924 ± 0.706
2.073AlaMet: 2.073 ± 0.499
3.628AlaAsn: 3.628 ± 0.577
4.146AlaPro: 4.146 ± 0.623
1.684AlaGln: 1.684 ± 0.411
5.571AlaArg: 5.571 ± 0.72
5.701AlaSer: 5.701 ± 1.701
5.831AlaThr: 5.831 ± 0.788
5.96AlaVal: 5.96 ± 0.77
1.944AlaTrp: 1.944 ± 0.307
2.591AlaTyr: 2.591 ± 0.452
0.0AlaXaa: 0.0 ± 0.0
Cys
0.777CysAla: 0.777 ± 0.258
0.0CysCys: 0.0 ± 0.0
1.166CysAsp: 1.166 ± 0.509
0.648CysGlu: 0.648 ± 0.328
0.777CysPhe: 0.777 ± 0.322
1.944CysGly: 1.944 ± 0.53
0.259CysHis: 0.259 ± 0.159
0.518CysIle: 0.518 ± 0.224
0.259CysLys: 0.259 ± 0.169
1.037CysLeu: 1.037 ± 0.301
0.389CysMet: 0.389 ± 0.18
0.518CysAsn: 0.518 ± 0.306
0.907CysPro: 0.907 ± 0.364
0.259CysGln: 0.259 ± 0.16
1.037CysArg: 1.037 ± 0.344
1.296CysSer: 1.296 ± 0.305
1.296CysThr: 1.296 ± 0.455
1.814CysVal: 1.814 ± 0.539
0.259CysTrp: 0.259 ± 0.154
0.389CysTyr: 0.389 ± 0.172
0.0CysXaa: 0.0 ± 0.0
Asp
4.664AspAla: 4.664 ± 0.564
0.648AspCys: 0.648 ± 0.357
4.017AspAsp: 4.017 ± 0.848
3.498AspGlu: 3.498 ± 0.647
2.721AspPhe: 2.721 ± 0.701
4.794AspGly: 4.794 ± 0.583
1.944AspHis: 1.944 ± 0.501
3.369AspIle: 3.369 ± 0.392
1.037AspLys: 1.037 ± 0.374
5.571AspLeu: 5.571 ± 0.879
1.814AspMet: 1.814 ± 0.449
1.425AspAsn: 1.425 ± 0.283
3.498AspPro: 3.498 ± 0.963
1.296AspGln: 1.296 ± 0.491
2.85AspArg: 2.85 ± 0.492
4.017AspSer: 4.017 ± 1.116
3.239AspThr: 3.239 ± 0.583
8.422AspVal: 8.422 ± 0.531
1.425AspTrp: 1.425 ± 0.603
1.555AspTyr: 1.555 ± 0.429
0.0AspXaa: 0.0 ± 0.0
Glu
2.98GluAla: 2.98 ± 0.398
0.907GluCys: 0.907 ± 0.432
2.98GluAsp: 2.98 ± 0.609
2.721GluGlu: 2.721 ± 0.905
1.944GluPhe: 1.944 ± 0.467
2.203GluGly: 2.203 ± 0.482
1.296GluHis: 1.296 ± 0.407
2.073GluIle: 2.073 ± 0.6
1.555GluLys: 1.555 ± 0.72
4.535GluLeu: 4.535 ± 0.683
1.814GluMet: 1.814 ± 0.573
1.555GluAsn: 1.555 ± 0.433
0.907GluPro: 0.907 ± 0.371
1.296GluGln: 1.296 ± 0.27
3.757GluArg: 3.757 ± 0.538
3.887GluSer: 3.887 ± 0.823
2.073GluThr: 2.073 ± 0.387
3.239GluVal: 3.239 ± 0.53
1.296GluTrp: 1.296 ± 0.463
2.073GluTyr: 2.073 ± 0.369
0.0GluXaa: 0.0 ± 0.0
Phe
2.591PheAla: 2.591 ± 0.663
0.777PheCys: 0.777 ± 0.28
3.628PheAsp: 3.628 ± 0.509
2.332PheGlu: 2.332 ± 0.624
1.037PhePhe: 1.037 ± 0.422
3.369PheGly: 3.369 ± 0.698
1.166PheHis: 1.166 ± 0.333
1.944PheIle: 1.944 ± 0.343
0.907PheLys: 0.907 ± 0.226
4.017PheLeu: 4.017 ± 0.857
0.518PheMet: 0.518 ± 0.188
1.425PheAsn: 1.425 ± 0.282
2.85PhePro: 2.85 ± 0.451
0.907PheGln: 0.907 ± 0.316
2.85PheArg: 2.85 ± 0.604
5.312PheSer: 5.312 ± 0.775
2.462PheThr: 2.462 ± 0.545
4.405PheVal: 4.405 ± 0.812
0.259PheTrp: 0.259 ± 0.166
1.555PheTyr: 1.555 ± 0.528
0.0PheXaa: 0.0 ± 0.0
Gly
2.85GlyAla: 2.85 ± 0.498
0.777GlyCys: 0.777 ± 0.201
2.98GlyAsp: 2.98 ± 0.619
2.85GlyGlu: 2.85 ± 0.567
3.369GlyPhe: 3.369 ± 0.482
2.85GlyGly: 2.85 ± 0.709
2.591GlyHis: 2.591 ± 0.506
4.017GlyIle: 4.017 ± 0.711
2.203GlyLys: 2.203 ± 0.379
6.219GlyLeu: 6.219 ± 0.841
1.944GlyMet: 1.944 ± 0.491
1.555GlyAsn: 1.555 ± 0.479
2.073GlyPro: 2.073 ± 0.355
1.944GlyGln: 1.944 ± 0.564
4.794GlyArg: 4.794 ± 1.196
3.757GlySer: 3.757 ± 0.901
3.498GlyThr: 3.498 ± 0.783
7.644GlyVal: 7.644 ± 0.714
0.907GlyTrp: 0.907 ± 0.247
2.591GlyTyr: 2.591 ± 0.783
0.0GlyXaa: 0.0 ± 0.0
His
3.369HisAla: 3.369 ± 0.446
0.518HisCys: 0.518 ± 0.211
1.296HisAsp: 1.296 ± 0.382
1.166HisGlu: 1.166 ± 0.208
1.425HisPhe: 1.425 ± 0.378
2.332HisGly: 2.332 ± 0.65
1.037HisHis: 1.037 ± 0.317
1.425HisIle: 1.425 ± 0.38
0.907HisLys: 0.907 ± 0.414
2.332HisLeu: 2.332 ± 0.576
1.037HisMet: 1.037 ± 0.394
0.777HisAsn: 0.777 ± 0.222
1.555HisPro: 1.555 ± 0.464
0.648HisGln: 0.648 ± 0.32
1.166HisArg: 1.166 ± 0.38
1.037HisSer: 1.037 ± 0.425
0.907HisThr: 0.907 ± 0.361
4.276HisVal: 4.276 ± 0.671
0.518HisTrp: 0.518 ± 0.339
1.296HisTyr: 1.296 ± 0.396
0.0HisXaa: 0.0 ± 0.0
Ile
3.628IleAla: 3.628 ± 0.575
1.425IleCys: 1.425 ± 0.484
3.498IleAsp: 3.498 ± 0.636
1.684IleGlu: 1.684 ± 0.477
1.555IlePhe: 1.555 ± 0.417
3.239IleGly: 3.239 ± 0.636
0.907IleHis: 0.907 ± 0.213
2.591IleIle: 2.591 ± 0.636
1.944IleLys: 1.944 ± 0.537
5.312IleLeu: 5.312 ± 0.683
1.166IleMet: 1.166 ± 0.405
2.591IleAsn: 2.591 ± 0.624
2.98IlePro: 2.98 ± 0.383
1.296IleGln: 1.296 ± 0.409
5.442IleArg: 5.442 ± 0.904
5.183IleSer: 5.183 ± 0.625
2.85IleThr: 2.85 ± 0.701
3.498IleVal: 3.498 ± 0.555
0.389IleTrp: 0.389 ± 0.231
1.296IleTyr: 1.296 ± 0.44
0.0IleXaa: 0.0 ± 0.0
Lys
1.166LysAla: 1.166 ± 0.42
0.389LysCys: 0.389 ± 0.214
2.073LysAsp: 2.073 ± 0.506
1.425LysGlu: 1.425 ± 0.444
1.555LysPhe: 1.555 ± 0.539
1.555LysGly: 1.555 ± 0.272
1.425LysHis: 1.425 ± 0.549
1.425LysIle: 1.425 ± 0.476
1.296LysLys: 1.296 ± 0.503
2.332LysLeu: 2.332 ± 0.63
0.907LysMet: 0.907 ± 0.356
1.037LysAsn: 1.037 ± 0.289
1.296LysPro: 1.296 ± 0.305
0.648LysGln: 0.648 ± 0.341
1.814LysArg: 1.814 ± 0.376
1.296LysSer: 1.296 ± 0.408
1.555LysThr: 1.555 ± 0.462
2.073LysVal: 2.073 ± 0.373
0.259LysTrp: 0.259 ± 0.211
1.814LysTyr: 1.814 ± 0.533
0.0LysXaa: 0.0 ± 0.0
Leu
7.385LeuAla: 7.385 ± 0.437
0.648LeuCys: 0.648 ± 0.289
5.183LeuAsp: 5.183 ± 1.057
5.053LeuGlu: 5.053 ± 1.046
3.628LeuPhe: 3.628 ± 0.525
6.09LeuGly: 6.09 ± 0.834
2.073LeuHis: 2.073 ± 0.648
3.498LeuIle: 3.498 ± 0.682
2.591LeuLys: 2.591 ± 0.468
8.292LeuLeu: 8.292 ± 0.592
3.498LeuMet: 3.498 ± 0.451
4.664LeuAsn: 4.664 ± 0.596
5.571LeuPro: 5.571 ± 0.879
3.11LeuGln: 3.11 ± 0.431
5.312LeuArg: 5.312 ± 0.658
9.07LeuSer: 9.07 ± 1.198
5.701LeuThr: 5.701 ± 0.785
4.535LeuVal: 4.535 ± 0.89
0.389LeuTrp: 0.389 ± 0.211
2.073LeuTyr: 2.073 ± 0.512
0.0LeuXaa: 0.0 ± 0.0
Met
1.944MetAla: 1.944 ± 0.348
0.777MetCys: 0.777 ± 0.285
0.777MetAsp: 0.777 ± 0.234
1.296MetGlu: 1.296 ± 0.325
1.944MetPhe: 1.944 ± 0.43
1.425MetGly: 1.425 ± 0.323
0.648MetHis: 0.648 ± 0.297
1.684MetIle: 1.684 ± 0.323
0.648MetLys: 0.648 ± 0.233
2.462MetLeu: 2.462 ± 0.426
0.518MetMet: 0.518 ± 0.232
1.814MetAsn: 1.814 ± 0.478
1.944MetPro: 1.944 ± 0.44
0.777MetGln: 0.777 ± 0.278
2.203MetArg: 2.203 ± 0.496
2.721MetSer: 2.721 ± 0.635
2.073MetThr: 2.073 ± 0.547
2.073MetVal: 2.073 ± 0.557
0.259MetTrp: 0.259 ± 0.153
1.037MetTyr: 1.037 ± 0.331
0.0MetXaa: 0.0 ± 0.0
Asn
3.628AsnAla: 3.628 ± 0.896
0.648AsnCys: 0.648 ± 0.35
1.425AsnAsp: 1.425 ± 0.292
1.425AsnGlu: 1.425 ± 0.403
1.555AsnPhe: 1.555 ± 0.304
3.628AsnGly: 3.628 ± 0.692
1.296AsnHis: 1.296 ± 0.359
2.591AsnIle: 2.591 ± 0.587
1.037AsnLys: 1.037 ± 0.493
2.073AsnLeu: 2.073 ± 0.655
1.296AsnMet: 1.296 ± 0.312
0.389AsnAsn: 0.389 ± 0.213
2.591AsnPro: 2.591 ± 0.633
1.296AsnGln: 1.296 ± 0.429
1.814AsnArg: 1.814 ± 0.48
3.239AsnSer: 3.239 ± 0.794
2.073AsnThr: 2.073 ± 0.496
3.887AsnVal: 3.887 ± 0.982
0.389AsnTrp: 0.389 ± 0.303
1.814AsnTyr: 1.814 ± 0.327
0.13AsnXaa: 0.13 ± 0.124
Pro
3.239ProAla: 3.239 ± 0.619
0.518ProCys: 0.518 ± 0.227
3.239ProAsp: 3.239 ± 0.741
1.944ProGlu: 1.944 ± 0.399
2.591ProPhe: 2.591 ± 0.454
2.85ProGly: 2.85 ± 0.684
1.555ProHis: 1.555 ± 0.376
2.591ProIle: 2.591 ± 0.405
1.425ProLys: 1.425 ± 0.337
5.701ProLeu: 5.701 ± 0.899
0.777ProMet: 0.777 ± 0.244
2.332ProAsn: 2.332 ± 0.581
3.239ProPro: 3.239 ± 0.617
1.814ProGln: 1.814 ± 0.274
4.535ProArg: 4.535 ± 0.819
4.535ProSer: 4.535 ± 1.024
3.498ProThr: 3.498 ± 0.668
4.405ProVal: 4.405 ± 0.641
0.648ProTrp: 0.648 ± 0.218
1.555ProTyr: 1.555 ± 0.392
0.0ProXaa: 0.0 ± 0.0
Gln
2.203GlnAla: 2.203 ± 0.468
0.518GlnCys: 0.518 ± 0.305
1.814GlnAsp: 1.814 ± 0.357
0.648GlnGlu: 0.648 ± 0.238
1.944GlnPhe: 1.944 ± 0.549
1.684GlnGly: 1.684 ± 0.41
1.296GlnHis: 1.296 ± 0.462
1.166GlnIle: 1.166 ± 0.382
0.389GlnLys: 0.389 ± 0.237
4.405GlnLeu: 4.405 ± 0.699
0.777GlnMet: 0.777 ± 0.266
1.037GlnAsn: 1.037 ± 0.438
1.166GlnPro: 1.166 ± 0.437
2.332GlnGln: 2.332 ± 0.722
2.203GlnArg: 2.203 ± 0.563
2.203GlnSer: 2.203 ± 0.63
1.684GlnThr: 1.684 ± 0.52
2.591GlnVal: 2.591 ± 0.462
0.389GlnTrp: 0.389 ± 0.163
1.425GlnTyr: 1.425 ± 0.409
0.0GlnXaa: 0.0 ± 0.0
Arg
5.053ArgAla: 5.053 ± 0.825
1.166ArgCys: 1.166 ± 0.356
4.017ArgAsp: 4.017 ± 0.51
3.757ArgGlu: 3.757 ± 0.525
3.757ArgPhe: 3.757 ± 0.536
3.369ArgGly: 3.369 ± 0.71
1.814ArgHis: 1.814 ± 0.456
3.628ArgIle: 3.628 ± 0.942
2.462ArgLys: 2.462 ± 0.481
4.794ArgLeu: 4.794 ± 0.913
2.462ArgMet: 2.462 ± 0.427
2.591ArgAsn: 2.591 ± 0.503
2.721ArgPro: 2.721 ± 0.525
3.11ArgGln: 3.11 ± 1.004
5.831ArgArg: 5.831 ± 1.17
5.701ArgSer: 5.701 ± 0.946
4.017ArgThr: 4.017 ± 0.522
5.701ArgVal: 5.701 ± 1.194
0.777ArgTrp: 0.777 ± 0.278
3.239ArgTyr: 3.239 ± 0.696
0.0ArgXaa: 0.0 ± 0.0
Ser
4.924SerAla: 4.924 ± 0.564
0.907SerCys: 0.907 ± 0.368
5.831SerAsp: 5.831 ± 1.272
3.11SerGlu: 3.11 ± 0.468
3.757SerPhe: 3.757 ± 0.577
5.312SerGly: 5.312 ± 1.039
3.11SerHis: 3.11 ± 0.659
4.794SerIle: 4.794 ± 0.878
1.684SerLys: 1.684 ± 0.511
6.737SerLeu: 6.737 ± 0.724
2.462SerMet: 2.462 ± 0.526
2.591SerAsn: 2.591 ± 0.479
4.405SerPro: 4.405 ± 1.116
3.369SerGln: 3.369 ± 0.885
5.312SerArg: 5.312 ± 0.886
7.256SerSer: 7.256 ± 1.732
6.867SerThr: 6.867 ± 1.166
6.608SerVal: 6.608 ± 1.124
1.425SerTrp: 1.425 ± 0.394
2.721SerTyr: 2.721 ± 0.451
0.0SerXaa: 0.0 ± 0.0
Thr
4.794ThrAla: 4.794 ± 0.587
0.648ThrCys: 0.648 ± 0.234
2.85ThrAsp: 2.85 ± 0.456
2.073ThrGlu: 2.073 ± 0.494
2.073ThrPhe: 2.073 ± 0.435
4.146ThrGly: 4.146 ± 0.838
1.296ThrHis: 1.296 ± 0.43
4.535ThrIle: 4.535 ± 0.681
1.814ThrLys: 1.814 ± 0.437
4.794ThrLeu: 4.794 ± 0.709
1.425ThrMet: 1.425 ± 0.447
2.073ThrAsn: 2.073 ± 0.419
4.535ThrPro: 4.535 ± 0.888
3.239ThrGln: 3.239 ± 0.632
3.887ThrArg: 3.887 ± 0.654
5.701ThrSer: 5.701 ± 0.944
4.664ThrThr: 4.664 ± 1.079
5.053ThrVal: 5.053 ± 0.661
0.518ThrTrp: 0.518 ± 0.234
2.591ThrTyr: 2.591 ± 0.479
0.0ThrXaa: 0.0 ± 0.0
Val
5.96ValAla: 5.96 ± 0.517
1.814ValCys: 1.814 ± 0.466
8.033ValAsp: 8.033 ± 1.342
5.053ValGlu: 5.053 ± 0.73
3.369ValPhe: 3.369 ± 0.896
5.571ValGly: 5.571 ± 1.167
1.814ValHis: 1.814 ± 0.58
5.312ValIle: 5.312 ± 0.806
1.814ValLys: 1.814 ± 0.445
8.163ValLeu: 8.163 ± 0.819
1.814ValMet: 1.814 ± 0.548
3.498ValAsn: 3.498 ± 0.689
3.887ValPro: 3.887 ± 0.973
1.944ValGln: 1.944 ± 0.403
5.701ValArg: 5.701 ± 0.833
7.904ValSer: 7.904 ± 0.715
5.701ValThr: 5.701 ± 0.738
6.219ValVal: 6.219 ± 1.094
0.648ValTrp: 0.648 ± 0.203
3.628ValTyr: 3.628 ± 0.673
0.0ValXaa: 0.0 ± 0.0
Trp
0.777TrpAla: 0.777 ± 0.246
0.0TrpCys: 0.0 ± 0.0
0.13TrpAsp: 0.13 ± 0.124
0.518TrpGlu: 0.518 ± 0.185
0.907TrpPhe: 0.907 ± 0.257
0.518TrpGly: 0.518 ± 0.225
0.777TrpHis: 0.777 ± 0.344
0.777TrpIle: 0.777 ± 0.328
0.777TrpLys: 0.777 ± 0.383
1.166TrpLeu: 1.166 ± 0.468
0.648TrpMet: 0.648 ± 0.174
1.425TrpAsn: 1.425 ± 0.286
0.13TrpPro: 0.13 ± 0.122
0.259TrpGln: 0.259 ± 0.265
0.907TrpArg: 0.907 ± 0.336
1.037TrpSer: 1.037 ± 0.324
0.777TrpThr: 0.777 ± 0.348
0.907TrpVal: 0.907 ± 0.31
0.0TrpTrp: 0.0 ± 0.0
0.518TrpTyr: 0.518 ± 0.173
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.239TyrAla: 3.239 ± 0.787
0.777TyrCys: 0.777 ± 0.219
2.591TyrAsp: 2.591 ± 0.676
1.684TyrGlu: 1.684 ± 0.281
1.425TyrPhe: 1.425 ± 0.393
2.203TyrGly: 2.203 ± 0.626
0.648TyrHis: 0.648 ± 0.179
1.037TyrIle: 1.037 ± 0.332
0.389TyrLys: 0.389 ± 0.244
3.498TyrLeu: 3.498 ± 0.92
1.555TyrMet: 1.555 ± 0.498
1.296TyrAsn: 1.296 ± 0.325
2.591TyrPro: 2.591 ± 0.398
0.648TyrGln: 0.648 ± 0.24
2.98TyrArg: 2.98 ± 0.684
2.332TyrSer: 2.332 ± 0.491
1.944TyrThr: 1.944 ± 0.611
4.664TyrVal: 4.664 ± 0.912
0.259TyrTrp: 0.259 ± 0.183
0.648TyrTyr: 0.648 ± 0.228
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.13XaaGly: 0.13 ± 0.124
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 12 proteins (7719 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski