Amino acid dipepetide frequency for Amorphotheca resinae ATCC 22711

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.743AlaAla: 8.743 ± 0.065	0.968AlaCys: 0.968 ± 0.015	4.04AlaAsp: 4.04 ± 0.033	5.223AlaGlu: 5.223 ± 0.046	2.982AlaPhe: 2.982 ± 0.027	5.748AlaGly: 5.748 ± 0.041	1.69AlaHis: 1.69 ± 0.019	4.149AlaIle: 4.149 ± 0.036	4.248AlaLys: 4.248 ± 0.036	7.542AlaLeu: 7.542 ± 0.05	1.907AlaMet: 1.907 ± 0.021	2.853AlaAsn: 2.853 ± 0.03	4.943AlaPro: 4.943 ± 0.049	3.291AlaGln: 3.291 ± 0.031	4.914AlaArg: 4.914 ± 0.038	7.254AlaSer: 7.254 ± 0.046	4.97AlaThr: 4.97 ± 0.038	5.047AlaVal: 5.047 ± 0.037	1.083AlaTrp: 1.083 ± 0.018	2.071AlaTyr: 2.071 ± 0.023	0.0AlaXaa: 0.0 ± 0.0
Cys	0.871CysAla: 0.871 ± 0.015	0.232CysCys: 0.232 ± 0.009	0.599CysAsp: 0.599 ± 0.013	0.576CysGlu: 0.576 ± 0.012	0.522CysPhe: 0.522 ± 0.011	0.908CysGly: 0.908 ± 0.019	0.319CysHis: 0.319 ± 0.009	0.691CysIle: 0.691 ± 0.014	0.507CysLys: 0.507 ± 0.011	1.2CysLeu: 1.2 ± 0.019	0.255CysMet: 0.255 ± 0.008	0.411CysAsn: 0.411 ± 0.012	0.665CysPro: 0.665 ± 0.014	0.406CysGln: 0.406 ± 0.01	0.712CysArg: 0.712 ± 0.013	0.896CysSer: 0.896 ± 0.018	0.658CysThr: 0.658 ± 0.013	0.746CysVal: 0.746 ± 0.014	0.2CysTrp: 0.2 ± 0.007	0.348CysTyr: 0.348 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	4.436AspAla: 4.436 ± 0.033	0.585AspCys: 0.585 ± 0.013	4.073AspAsp: 4.073 ± 0.049	4.614AspGlu: 4.614 ± 0.041	2.172AspPhe: 2.172 ± 0.026	4.109AspGly: 4.109 ± 0.038	1.162AspHis: 1.162 ± 0.016	3.128AspIle: 3.128 ± 0.027	2.311AspLys: 2.311 ± 0.024	5.003AspLeu: 5.003 ± 0.034	1.23AspMet: 1.23 ± 0.02	1.806AspAsn: 1.806 ± 0.02	3.392AspPro: 3.392 ± 0.032	1.763AspGln: 1.763 ± 0.021	2.934AspArg: 2.934 ± 0.032	4.07AspSer: 4.07 ± 0.034	2.801AspThr: 2.801 ± 0.025	3.462AspVal: 3.462 ± 0.029	0.834AspTrp: 0.834 ± 0.015	1.544AspTyr: 1.544 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	5.542GluAla: 5.542 ± 0.046	0.596GluCys: 0.596 ± 0.011	4.415GluAsp: 4.415 ± 0.04	6.181GluGlu: 6.181 ± 0.072	1.988GluPhe: 1.988 ± 0.025	4.121GluGly: 4.121 ± 0.038	1.338GluHis: 1.338 ± 0.021	3.31GluIle: 3.31 ± 0.031	4.151GluLys: 4.151 ± 0.04	5.193GluLeu: 5.193 ± 0.045	1.562GluMet: 1.562 ± 0.018	2.406GluAsn: 2.406 ± 0.023	2.851GluPro: 2.851 ± 0.033	2.433GluGln: 2.433 ± 0.025	4.251GluArg: 4.251 ± 0.042	4.357GluSer: 4.357 ± 0.039	3.468GluThr: 3.468 ± 0.03	3.751GluVal: 3.751 ± 0.032	0.887GluTrp: 0.887 ± 0.014	1.736GluTyr: 1.736 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	2.876PheAla: 2.876 ± 0.03	0.565PheCys: 0.565 ± 0.011	2.205PheAsp: 2.205 ± 0.024	2.214PheGlu: 2.214 ± 0.027	1.557PhePhe: 1.557 ± 0.023	2.808PheGly: 2.808 ± 0.032	0.841PheHis: 0.841 ± 0.016	1.802PheIle: 1.802 ± 0.024	1.554PheLys: 1.554 ± 0.02	3.473PheLeu: 3.473 ± 0.032	0.78PheMet: 0.78 ± 0.014	1.425PheAsn: 1.425 ± 0.018	1.988PhePro: 1.988 ± 0.024	1.376PheGln: 1.376 ± 0.018	1.91PheArg: 1.91 ± 0.023	3.041PheSer: 3.041 ± 0.027	2.102PheThr: 2.102 ± 0.023	2.265PheVal: 2.265 ± 0.024	0.63PheTrp: 0.63 ± 0.014	1.097PheTyr: 1.097 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	5.156GlyAla: 5.156 ± 0.041	0.838GlyCys: 0.838 ± 0.015	3.579GlyAsp: 3.579 ± 0.027	3.97GlyGlu: 3.97 ± 0.036	2.871GlyPhe: 2.871 ± 0.026	6.036GlyGly: 6.036 ± 0.059	1.573GlyHis: 1.573 ± 0.018	3.699GlyIle: 3.699 ± 0.031	3.776GlyLys: 3.776 ± 0.037	6.045GlyLeu: 6.045 ± 0.043	1.671GlyMet: 1.671 ± 0.023	2.582GlyAsn: 2.582 ± 0.028	3.445GlyPro: 3.445 ± 0.034	2.466GlyGln: 2.466 ± 0.025	4.358GlyArg: 4.358 ± 0.039	5.831GlySer: 5.831 ± 0.045	3.972GlyThr: 3.972 ± 0.035	4.288GlyVal: 4.288 ± 0.032	1.174GlyTrp: 1.174 ± 0.017	2.111GlyTyr: 2.111 ± 0.027	0.0GlyXaa: 0.0 ± 0.0
His	1.673HisAla: 1.673 ± 0.02	0.306HisCys: 0.306 ± 0.009	1.223HisAsp: 1.223 ± 0.017	1.287HisGlu: 1.287 ± 0.021	0.866HisPhe: 0.866 ± 0.013	1.625HisGly: 1.625 ± 0.022	0.801HisHis: 0.801 ± 0.017	1.208HisIle: 1.208 ± 0.018	0.933HisLys: 0.933 ± 0.015	2.209HisLeu: 2.209 ± 0.026	0.472HisMet: 0.472 ± 0.011	0.827HisAsn: 0.827 ± 0.013	1.675HisPro: 1.675 ± 0.021	0.94HisGln: 0.94 ± 0.018	1.441HisArg: 1.441 ± 0.021	1.804HisSer: 1.804 ± 0.02	1.22HisThr: 1.22 ± 0.019	1.327HisVal: 1.327 ± 0.019	0.304HisTrp: 0.304 ± 0.007	0.681HisTyr: 0.681 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.139IleAla: 4.139 ± 0.035	0.761IleCys: 0.761 ± 0.013	2.925IleAsp: 2.925 ± 0.027	3.062IleGlu: 3.062 ± 0.029	2.029IlePhe: 2.029 ± 0.03	3.2IleGly: 3.2 ± 0.035	1.201IleHis: 1.201 ± 0.018	2.698IleIle: 2.698 ± 0.026	2.399IleLys: 2.399 ± 0.026	4.715IleLeu: 4.715 ± 0.037	1.041IleMet: 1.041 ± 0.013	1.807IleAsn: 1.807 ± 0.022	3.312IlePro: 3.312 ± 0.03	1.923IleGln: 1.923 ± 0.022	2.921IleArg: 2.921 ± 0.026	4.177IleSer: 4.177 ± 0.036	2.935IleThr: 2.935 ± 0.031	3.087IleVal: 3.087 ± 0.028	0.737IleTrp: 0.737 ± 0.015	1.476IleTyr: 1.476 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	4.544LysAla: 4.544 ± 0.038	0.495LysCys: 0.495 ± 0.011	2.867LysAsp: 2.867 ± 0.028	3.92LysGlu: 3.92 ± 0.041	1.507LysPhe: 1.507 ± 0.022	3.287LysGly: 3.287 ± 0.032	1.153LysHis: 1.153 ± 0.017	2.505LysIle: 2.505 ± 0.025	3.762LysLys: 3.762 ± 0.049	4.205LysLeu: 4.205 ± 0.036	1.092LysMet: 1.092 ± 0.016	1.808LysAsn: 1.808 ± 0.022	2.875LysPro: 2.875 ± 0.03	1.85LysGln: 1.85 ± 0.021	3.607LysArg: 3.607 ± 0.033	3.758LysSer: 3.758 ± 0.028	2.927LysThr: 2.927 ± 0.028	2.944LysVal: 2.944 ± 0.03	0.676LysTrp: 0.676 ± 0.012	1.444LysTyr: 1.444 ± 0.02	0.0LysXaa: 0.0 ± 0.0
Leu	7.505LeuAla: 7.505 ± 0.049	1.159LeuCys: 1.159 ± 0.017	5.032LeuAsp: 5.032 ± 0.033	5.679LeuGlu: 5.679 ± 0.046	3.284LeuPhe: 3.284 ± 0.036	5.902LeuGly: 5.902 ± 0.04	2.115LeuHis: 2.115 ± 0.021	3.991LeuIle: 3.991 ± 0.034	4.47LeuLys: 4.47 ± 0.041	8.392LeuLeu: 8.392 ± 0.071	1.732LeuMet: 1.732 ± 0.023	3.132LeuAsn: 3.132 ± 0.031	5.659LeuPro: 5.659 ± 0.036	3.752LeuGln: 3.752 ± 0.035	5.664LeuArg: 5.664 ± 0.044	7.398LeuSer: 7.398 ± 0.051	4.73LeuThr: 4.73 ± 0.037	5.159LeuVal: 5.159 ± 0.042	1.141LeuTrp: 1.141 ± 0.019	2.394LeuTyr: 2.394 ± 0.023	0.0LeuXaa: 0.0 ± 0.0
Met	2.205MetAla: 2.205 ± 0.026	0.231MetCys: 0.231 ± 0.008	1.257MetAsp: 1.257 ± 0.019	1.353MetGlu: 1.353 ± 0.018	0.71MetPhe: 0.71 ± 0.013	1.527MetGly: 1.527 ± 0.02	0.449MetHis: 0.449 ± 0.011	1.045MetIle: 1.045 ± 0.015	1.077MetLys: 1.077 ± 0.015	1.79MetLeu: 1.79 ± 0.02	0.6MetMet: 0.6 ± 0.013	0.843MetAsn: 0.843 ± 0.015	1.266MetPro: 1.266 ± 0.021	0.857MetGln: 0.857 ± 0.016	1.27MetArg: 1.27 ± 0.018	1.843MetSer: 1.843 ± 0.021	1.257MetThr: 1.257 ± 0.016	1.258MetVal: 1.258 ± 0.017	0.264MetTrp: 0.264 ± 0.008	0.53MetTyr: 0.53 ± 0.012	0.0MetXaa: 0.0 ± 0.0
Asn	3.007AsnAla: 3.007 ± 0.028	0.435AsnCys: 0.435 ± 0.01	1.886AsnAsp: 1.886 ± 0.024	2.078AsnGlu: 2.078 ± 0.025	1.364AsnPhe: 1.364 ± 0.019	3.118AsnGly: 3.118 ± 0.035	0.838AsnHis: 0.838 ± 0.014	2.078AsnIle: 2.078 ± 0.022	1.555AsnLys: 1.555 ± 0.021	3.285AsnLeu: 3.285 ± 0.028	0.818AsnMet: 0.818 ± 0.013	1.511AsnAsn: 1.511 ± 0.023	2.632AsnPro: 2.632 ± 0.031	1.388AsnGln: 1.388 ± 0.02	1.988AsnArg: 1.988 ± 0.021	2.873AsnSer: 2.873 ± 0.035	2.21AsnThr: 2.21 ± 0.022	2.223AsnVal: 2.223 ± 0.025	0.533AsnTrp: 0.533 ± 0.011	1.071AsnTyr: 1.071 ± 0.017	0.0AsnXaa: 0.0 ± 0.0
Pro	5.291ProAla: 5.291 ± 0.055	0.504ProCys: 0.504 ± 0.012	3.117ProAsp: 3.117 ± 0.027	3.935ProGlu: 3.935 ± 0.035	2.098ProPhe: 2.098 ± 0.024	3.952ProGly: 3.952 ± 0.035	1.332ProHis: 1.332 ± 0.021	2.745ProIle: 2.745 ± 0.026	2.925ProLys: 2.925 ± 0.032	4.899ProLeu: 4.899 ± 0.037	1.084ProMet: 1.084 ± 0.018	2.326ProAsn: 2.326 ± 0.026	5.679ProPro: 5.679 ± 0.079	2.597ProGln: 2.597 ± 0.034	3.656ProArg: 3.656 ± 0.038	6.458ProSer: 6.458 ± 0.054	4.176ProThr: 4.176 ± 0.04	3.538ProVal: 3.538 ± 0.029	0.705ProTrp: 0.705 ± 0.014	1.625ProTyr: 1.625 ± 0.023	0.0ProXaa: 0.0 ± 0.0
Gln	3.27GlnAla: 3.27 ± 0.032	0.413GlnCys: 0.413 ± 0.011	1.972GlnAsp: 1.972 ± 0.024	2.456GlnGlu: 2.456 ± 0.027	1.247GlnPhe: 1.247 ± 0.017	2.372GlnGly: 2.372 ± 0.026	1.023GlnHis: 1.023 ± 0.018	1.934GlnIle: 1.934 ± 0.02	2.107GlnLys: 2.107 ± 0.023	3.29GlnLeu: 3.29 ± 0.033	0.897GlnMet: 0.897 ± 0.016	1.624GlnAsn: 1.624 ± 0.021	2.443GlnPro: 2.443 ± 0.036	2.294GlnGln: 2.294 ± 0.05	2.648GlnArg: 2.648 ± 0.024	3.156GlnSer: 3.156 ± 0.036	2.266GlnThr: 2.266 ± 0.024	2.068GlnVal: 2.068 ± 0.021	0.517GlnTrp: 0.517 ± 0.012	1.149GlnTyr: 1.149 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	4.755ArgAla: 4.755 ± 0.036	0.728ArgCys: 0.728 ± 0.013	3.341ArgAsp: 3.341 ± 0.035	4.159ArgGlu: 4.159 ± 0.033	2.057ArgPhe: 2.057 ± 0.022	3.983ArgGly: 3.983 ± 0.036	1.486ArgHis: 1.486 ± 0.022	3.057ArgIle: 3.057 ± 0.031	3.718ArgLys: 3.718 ± 0.034	5.333ArgLeu: 5.333 ± 0.04	1.359ArgMet: 1.359 ± 0.018	2.319ArgAsn: 2.319 ± 0.025	3.623ArgPro: 3.623 ± 0.036	2.545ArgGln: 2.545 ± 0.024	5.284ArgArg: 5.284 ± 0.05	4.894ArgSer: 4.894 ± 0.042	3.266ArgThr: 3.266 ± 0.029	3.252ArgVal: 3.252 ± 0.029	0.908ArgTrp: 0.908 ± 0.017	1.679ArgTyr: 1.679 ± 0.022	0.0ArgXaa: 0.0 ± 0.0
Ser	6.581SerAla: 6.581 ± 0.045	0.848SerCys: 0.848 ± 0.017	4.139SerAsp: 4.139 ± 0.034	4.258SerGlu: 4.258 ± 0.038	3.024SerPhe: 3.024 ± 0.027	5.663SerGly: 5.663 ± 0.034	1.893SerHis: 1.893 ± 0.022	4.256SerIle: 4.256 ± 0.033	4.051SerLys: 4.051 ± 0.037	7.236SerLeu: 7.236 ± 0.049	1.73SerMet: 1.73 ± 0.022	3.215SerAsn: 3.215 ± 0.031	6.015SerPro: 6.015 ± 0.056	3.378SerGln: 3.378 ± 0.037	5.175SerArg: 5.175 ± 0.047	9.546SerSer: 9.546 ± 0.097	5.809SerThr: 5.809 ± 0.045	4.41SerVal: 4.41 ± 0.036	1.072SerTrp: 1.072 ± 0.016	2.128SerTyr: 2.128 ± 0.023	0.0SerXaa: 0.0 ± 0.0
Thr	4.985ThrAla: 4.985 ± 0.034	0.711ThrCys: 0.711 ± 0.014	2.677ThrAsp: 2.677 ± 0.029	3.08ThrGlu: 3.08 ± 0.03	2.206ThrPhe: 2.206 ± 0.022	4.143ThrGly: 4.143 ± 0.035	1.238ThrHis: 1.238 ± 0.017	3.155ThrIle: 3.155 ± 0.029	2.673ThrLys: 2.673 ± 0.023	5.164ThrLeu: 5.164 ± 0.041	1.163ThrMet: 1.163 ± 0.017	2.105ThrAsn: 2.105 ± 0.023	4.579ThrPro: 4.579 ± 0.043	2.015ThrGln: 2.015 ± 0.022	3.13ThrArg: 3.13 ± 0.025	5.512ThrSer: 5.512 ± 0.044	4.178ThrThr: 4.178 ± 0.042	3.564ThrVal: 3.564 ± 0.031	0.779ThrTrp: 0.779 ± 0.014	1.647ThrTyr: 1.647 ± 0.021	0.0ThrXaa: 0.0 ± 0.0
Val	4.906ValAla: 4.906 ± 0.037	0.762ValCys: 0.762 ± 0.013	3.547ValAsp: 3.547 ± 0.031	3.967ValGlu: 3.967 ± 0.033	2.323ValPhe: 2.323 ± 0.03	3.939ValGly: 3.939 ± 0.038	1.299ValHis: 1.299 ± 0.018	2.884ValIle: 2.884 ± 0.028	3.026ValLys: 3.026 ± 0.032	5.385ValLeu: 5.385 ± 0.041	1.283ValMet: 1.283 ± 0.019	2.114ValAsn: 2.114 ± 0.025	3.5ValPro: 3.5 ± 0.029	2.219ValGln: 2.219 ± 0.026	3.352ValArg: 3.352 ± 0.032	4.493ValSer: 4.493 ± 0.036	3.298ValThr: 3.298 ± 0.031	4.126ValVal: 4.126 ± 0.039	0.833ValTrp: 0.833 ± 0.015	1.665ValTyr: 1.665 ± 0.022	0.0ValXaa: 0.0 ± 0.0
Trp	1.094TrpAla: 1.094 ± 0.017	0.182TrpCys: 0.182 ± 0.006	0.895TrpAsp: 0.895 ± 0.015	0.875TrpGlu: 0.875 ± 0.014	0.512TrpPhe: 0.512 ± 0.013	0.92TrpGly: 0.92 ± 0.016	0.335TrpHis: 0.335 ± 0.009	0.731TrpIle: 0.731 ± 0.014	0.803TrpLys: 0.803 ± 0.012	1.274TrpLeu: 1.274 ± 0.019	0.365TrpMet: 0.365 ± 0.009	0.618TrpAsn: 0.618 ± 0.013	0.571TrpPro: 0.571 ± 0.012	0.521TrpGln: 0.521 ± 0.011	0.924TrpArg: 0.924 ± 0.016	0.983TrpSer: 0.983 ± 0.016	0.853TrpThr: 0.853 ± 0.013	0.825TrpVal: 0.825 ± 0.013	0.266TrpTrp: 0.266 ± 0.008	0.411TrpTyr: 0.411 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.084TyrAla: 2.084 ± 0.024	0.403TyrCys: 0.403 ± 0.01	1.64TyrAsp: 1.64 ± 0.022	1.648TyrGlu: 1.648 ± 0.022	1.191TyrPhe: 1.191 ± 0.018	2.081TyrGly: 2.081 ± 0.028	0.736TyrHis: 0.736 ± 0.014	1.48TyrIle: 1.48 ± 0.021	1.18TyrLys: 1.18 ± 0.016	2.658TyrLeu: 2.658 ± 0.029	0.594TyrMet: 0.594 ± 0.013	1.158TyrAsn: 1.158 ± 0.017	1.53TyrPro: 1.53 ± 0.021	1.127TyrGln: 1.127 ± 0.018	1.605TyrArg: 1.605 ± 0.019	2.083TyrSer: 2.083 ± 0.023	1.61TyrThr: 1.61 ± 0.021	1.582TyrVal: 1.582 ± 0.021	0.416TyrTrp: 0.416 ± 0.01	0.939TyrTyr: 0.939 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9640 proteins (4384405 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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