Amino acid dipepetide frequency for Chitinophaga costaii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
9.347AlaAla: 9.347 ± 0.129
0.843AlaCys: 0.843 ± 0.029
4.452AlaAsp: 4.452 ± 0.06
3.714AlaGlu: 3.714 ± 0.062
3.772AlaPhe: 3.772 ± 0.047
6.736AlaGly: 6.736 ± 0.082
1.85AlaHis: 1.85 ± 0.039
5.498AlaIle: 5.498 ± 0.077
3.863AlaLys: 3.863 ± 0.06
8.624AlaLeu: 8.624 ± 0.111
2.104AlaMet: 2.104 ± 0.039
3.756AlaAsn: 3.756 ± 0.058
3.264AlaPro: 3.264 ± 0.058
3.858AlaGln: 3.858 ± 0.052
3.553AlaArg: 3.553 ± 0.053
5.057AlaSer: 5.057 ± 0.067
5.429AlaThr: 5.429 ± 0.094
5.548AlaVal: 5.548 ± 0.067
1.037AlaTrp: 1.037 ± 0.025
3.502AlaTyr: 3.502 ± 0.052
0.0AlaXaa: 0.0 ± 0.0
Cys
0.604CysAla: 0.604 ± 0.022
0.177CysCys: 0.177 ± 0.013
0.359CysAsp: 0.359 ± 0.014
0.343CysGlu: 0.343 ± 0.014
0.436CysPhe: 0.436 ± 0.02
0.642CysGly: 0.642 ± 0.022
0.214CysHis: 0.214 ± 0.013
0.58CysIle: 0.58 ± 0.02
0.444CysLys: 0.444 ± 0.019
0.877CysLeu: 0.877 ± 0.027
0.234CysMet: 0.234 ± 0.012
0.367CysAsn: 0.367 ± 0.018
0.351CysPro: 0.351 ± 0.017
0.271CysGln: 0.271 ± 0.014
0.357CysArg: 0.357 ± 0.016
0.525CysSer: 0.525 ± 0.024
0.487CysThr: 0.487 ± 0.021
0.498CysVal: 0.498 ± 0.022
0.123CysTrp: 0.123 ± 0.009
0.354CysTyr: 0.354 ± 0.017
0.0CysXaa: 0.0 ± 0.0
Asp
4.653AspAla: 4.653 ± 0.061
0.354AspCys: 0.354 ± 0.015
2.394AspAsp: 2.394 ± 0.048
2.775AspGlu: 2.775 ± 0.049
2.648AspPhe: 2.648 ± 0.049
3.64AspGly: 3.64 ± 0.06
1.159AspHis: 1.159 ± 0.03
3.733AspIle: 3.733 ± 0.049
3.24AspLys: 3.24 ± 0.048
4.722AspLeu: 4.722 ± 0.048
1.174AspMet: 1.174 ± 0.029
2.533AspAsn: 2.533 ± 0.045
2.344AspPro: 2.344 ± 0.048
1.959AspGln: 1.959 ± 0.038
2.109AspArg: 2.109 ± 0.038
2.936AspSer: 2.936 ± 0.057
3.093AspThr: 3.093 ± 0.072
3.324AspVal: 3.324 ± 0.045
0.707AspTrp: 0.707 ± 0.023
2.492AspTyr: 2.492 ± 0.047
0.0AspXaa: 0.0 ± 0.0
Glu
4.376GluAla: 4.376 ± 0.057
0.329GluCys: 0.329 ± 0.016
2.484GluAsp: 2.484 ± 0.05
3.13GluGlu: 3.13 ± 0.062
1.758GluPhe: 1.758 ± 0.046
3.253GluGly: 3.253 ± 0.055
1.134GluHis: 1.134 ± 0.026
3.321GluIle: 3.321 ± 0.059
3.984GluLys: 3.984 ± 0.062
4.846GluLeu: 4.846 ± 0.071
1.379GluMet: 1.379 ± 0.034
2.731GluAsn: 2.731 ± 0.041
1.531GluPro: 1.531 ± 0.037
2.573GluGln: 2.573 ± 0.056
2.382GluArg: 2.382 ± 0.043
2.35GluSer: 2.35 ± 0.041
2.599GluThr: 2.599 ± 0.041
3.447GluVal: 3.447 ± 0.047
0.62GluTrp: 0.62 ± 0.022
1.771GluTyr: 1.771 ± 0.038
0.0GluXaa: 0.0 ± 0.0
Phe
3.281PheAla: 3.281 ± 0.053
0.449PheCys: 0.449 ± 0.019
2.574PheAsp: 2.574 ± 0.043
2.23PheGlu: 2.23 ± 0.038
2.299PhePhe: 2.299 ± 0.047
3.084PheGly: 3.084 ± 0.051
1.018PheHis: 1.018 ± 0.029
2.897PheIle: 2.897 ± 0.051
2.445PheLys: 2.445 ± 0.046
4.246PheLeu: 4.246 ± 0.06
1.06PheMet: 1.06 ± 0.027
2.634PheAsn: 2.634 ± 0.044
1.864PhePro: 1.864 ± 0.035
1.592PheGln: 1.592 ± 0.036
2.033PheArg: 2.033 ± 0.037
3.444PheSer: 3.444 ± 0.052
3.241PheThr: 3.241 ± 0.048
2.704PheVal: 2.704 ± 0.044
0.512PheTrp: 0.512 ± 0.019
2.019PheTyr: 2.019 ± 0.041
0.0PheXaa: 0.0 ± 0.0
Gly
5.255GlyAla: 5.255 ± 0.065
0.657GlyCys: 0.657 ± 0.031
3.341GlyAsp: 3.341 ± 0.045
3.236GlyGlu: 3.236 ± 0.05
3.384GlyPhe: 3.384 ± 0.053
5.286GlyGly: 5.286 ± 0.109
1.595GlyHis: 1.595 ± 0.035
5.15GlyIle: 5.15 ± 0.063
4.591GlyLys: 4.591 ± 0.064
6.428GlyLeu: 6.428 ± 0.077
1.868GlyMet: 1.868 ± 0.043
3.689GlyAsn: 3.689 ± 0.061
1.779GlyPro: 1.779 ± 0.041
2.783GlyGln: 2.783 ± 0.049
2.92GlyArg: 2.92 ± 0.05
4.275GlySer: 4.275 ± 0.059
4.343GlyThr: 4.343 ± 0.076
4.649GlyVal: 4.649 ± 0.06
1.046GlyTrp: 1.046 ± 0.028
3.184GlyTyr: 3.184 ± 0.06
0.0GlyXaa: 0.0 ± 0.0
His
1.802HisAla: 1.802 ± 0.033
0.251HisCys: 0.251 ± 0.014
1.084HisAsp: 1.084 ± 0.03
0.977HisGlu: 0.977 ± 0.028
1.35HisPhe: 1.35 ± 0.028
1.391HisGly: 1.391 ± 0.028
0.79HisHis: 0.79 ± 0.028
1.577HisIle: 1.577 ± 0.036
1.043HisLys: 1.043 ± 0.025
2.473HisLeu: 2.473 ± 0.049
0.469HisMet: 0.469 ± 0.019
1.02HisAsn: 1.02 ± 0.026
1.392HisPro: 1.392 ± 0.032
1.004HisGln: 1.004 ± 0.028
1.057HisArg: 1.057 ± 0.025
1.223HisSer: 1.223 ± 0.03
1.511HisThr: 1.511 ± 0.033
1.232HisVal: 1.232 ± 0.031
0.334HisTrp: 0.334 ± 0.016
1.187HisTyr: 1.187 ± 0.032
0.0HisXaa: 0.0 ± 0.0
Ile
5.753IleAla: 5.753 ± 0.074
0.625IleCys: 0.625 ± 0.024
3.6IleAsp: 3.6 ± 0.049
2.903IleGlu: 2.903 ± 0.05
2.805IlePhe: 2.805 ± 0.047
4.381IleGly: 4.381 ± 0.066
1.497IleHis: 1.497 ± 0.036
4.061IleIle: 4.061 ± 0.065
3.558IleLys: 3.558 ± 0.043
5.698IleLeu: 5.698 ± 0.068
1.197IleMet: 1.197 ± 0.037
3.354IleAsn: 3.354 ± 0.057
3.086IlePro: 3.086 ± 0.043
2.294IleGln: 2.294 ± 0.039
3.152IleArg: 3.152 ± 0.046
4.395IleSer: 4.395 ± 0.058
4.641IleThr: 4.641 ± 0.081
3.946IleVal: 3.946 ± 0.057
0.679IleTrp: 0.679 ± 0.024
2.403IleTyr: 2.403 ± 0.043
0.0IleXaa: 0.0 ± 0.0
Lys
4.916LysAla: 4.916 ± 0.075
0.288LysCys: 0.288 ± 0.016
3.538LysAsp: 3.538 ± 0.061
3.467LysGlu: 3.467 ± 0.061
1.967LysPhe: 1.967 ± 0.035
3.97LysGly: 3.97 ± 0.057
1.105LysHis: 1.105 ± 0.031
3.795LysIle: 3.795 ± 0.059
3.986LysLys: 3.986 ± 0.071
4.83LysLeu: 4.83 ± 0.06
1.599LysMet: 1.599 ± 0.041
2.956LysAsn: 2.956 ± 0.056
2.367LysPro: 2.367 ± 0.048
2.537LysGln: 2.537 ± 0.042
2.384LysArg: 2.384 ± 0.044
2.955LysSer: 2.955 ± 0.049
3.481LysThr: 3.481 ± 0.05
3.803LysVal: 3.803 ± 0.056
0.718LysTrp: 0.718 ± 0.021
2.214LysTyr: 2.214 ± 0.042
0.0LysXaa: 0.0 ± 0.0
Leu
7.939LeuAla: 7.939 ± 0.094
0.921LeuCys: 0.921 ± 0.025
4.922LeuAsp: 4.922 ± 0.06
5.162LeuGlu: 5.162 ± 0.078
4.403LeuPhe: 4.403 ± 0.067
6.061LeuGly: 6.061 ± 0.067
2.715LeuHis: 2.715 ± 0.048
5.179LeuIle: 5.179 ± 0.078
5.652LeuLys: 5.652 ± 0.069
11.543LeuLeu: 11.543 ± 0.138
2.059LeuMet: 2.059 ± 0.034
4.586LeuAsn: 4.586 ± 0.065
5.212LeuPro: 5.212 ± 0.073
5.816LeuGln: 5.816 ± 0.077
4.693LeuArg: 4.693 ± 0.066
6.585LeuSer: 6.585 ± 0.077
5.475LeuThr: 5.475 ± 0.08
6.061LeuVal: 6.061 ± 0.079
0.997LeuTrp: 0.997 ± 0.029
3.541LeuTyr: 3.541 ± 0.053
0.0LeuXaa: 0.0 ± 0.0
Met
2.14MetAla: 2.14 ± 0.038
0.134MetCys: 0.134 ± 0.01
1.243MetAsp: 1.243 ± 0.03
1.464MetGlu: 1.464 ± 0.034
0.758MetPhe: 0.758 ± 0.025
1.605MetGly: 1.605 ± 0.036
0.568MetHis: 0.568 ± 0.023
1.342MetIle: 1.342 ± 0.037
1.692MetLys: 1.692 ± 0.032
2.305MetLeu: 2.305 ± 0.048
0.612MetMet: 0.612 ± 0.022
1.183MetAsn: 1.183 ± 0.027
1.153MetPro: 1.153 ± 0.031
1.275MetGln: 1.275 ± 0.03
1.085MetArg: 1.085 ± 0.024
1.293MetSer: 1.293 ± 0.031
1.162MetThr: 1.162 ± 0.029
1.474MetVal: 1.474 ± 0.034
0.185MetTrp: 0.185 ± 0.011
0.725MetTyr: 0.725 ± 0.023
0.0MetXaa: 0.0 ± 0.0
Asn
4.168AsnAla: 4.168 ± 0.054
0.321AsnCys: 0.321 ± 0.018
2.609AsnAsp: 2.609 ± 0.043
2.318AsnGlu: 2.318 ± 0.036
2.265AsnPhe: 2.265 ± 0.045
3.906AsnGly: 3.906 ± 0.07
0.951AsnHis: 0.951 ± 0.03
3.713AsnIle: 3.713 ± 0.057
2.845AsnLys: 2.845 ± 0.049
4.425AsnLeu: 4.425 ± 0.062
1.136AsnMet: 1.136 ± 0.03
2.922AsnAsn: 2.922 ± 0.055
2.35AsnPro: 2.35 ± 0.045
1.724AsnGln: 1.724 ± 0.036
2.131AsnArg: 2.131 ± 0.047
2.702AsnSer: 2.702 ± 0.06
3.354AsnThr: 3.354 ± 0.057
3.133AsnVal: 3.133 ± 0.056
0.667AsnTrp: 0.667 ± 0.023
2.296AsnTyr: 2.296 ± 0.049
0.0AsnXaa: 0.0 ± 0.0
Pro
4.592ProAla: 4.592 ± 0.081
0.257ProCys: 0.257 ± 0.015
2.803ProAsp: 2.803 ± 0.056
2.593ProGlu: 2.593 ± 0.046
2.033ProPhe: 2.033 ± 0.034
3.358ProGly: 3.358 ± 0.06
0.928ProHis: 0.928 ± 0.023
2.296ProIle: 2.296 ± 0.04
1.81ProLys: 1.81 ± 0.037
4.232ProLeu: 4.232 ± 0.063
0.905ProMet: 0.905 ± 0.024
1.839ProAsn: 1.839 ± 0.035
1.604ProPro: 1.604 ± 0.06
1.711ProGln: 1.711 ± 0.035
1.385ProArg: 1.385 ± 0.033
2.32ProSer: 2.32 ± 0.04
2.263ProThr: 2.263 ± 0.043
3.791ProVal: 3.791 ± 0.068
0.48ProTrp: 0.48 ± 0.018
1.771ProTyr: 1.771 ± 0.036
0.0ProXaa: 0.0 ± 0.0
Gln
3.858GlnAla: 3.858 ± 0.07
0.259GlnCys: 0.259 ± 0.014
2.021GlnAsp: 2.021 ± 0.034
2.526GlnGlu: 2.526 ± 0.04
1.826GlnPhe: 1.826 ± 0.038
2.573GlnGly: 2.573 ± 0.047
1.387GlnHis: 1.387 ± 0.033
2.134GlnIle: 2.134 ± 0.045
2.134GlnLys: 2.134 ± 0.044
5.102GlnLeu: 5.102 ± 0.06
0.981GlnMet: 0.981 ± 0.029
1.696GlnAsn: 1.696 ± 0.036
2.181GlnPro: 2.181 ± 0.042
3.469GlnGln: 3.469 ± 0.061
2.174GlnArg: 2.174 ± 0.047
2.246GlnSer: 2.246 ± 0.042
2.332GlnThr: 2.332 ± 0.04
3.284GlnVal: 3.284 ± 0.052
0.655GlnTrp: 0.655 ± 0.022
1.985GlnTyr: 1.985 ± 0.042
0.0GlnXaa: 0.0 ± 0.0
Arg
2.942ArgAla: 2.942 ± 0.046
0.298ArgCys: 0.298 ± 0.016
2.081ArgAsp: 2.081 ± 0.037
2.46ArgGlu: 2.46 ± 0.048
2.225ArgPhe: 2.225 ± 0.039
2.324ArgGly: 2.324 ± 0.043
1.06ArgHis: 1.06 ± 0.027
3.158ArgIle: 3.158 ± 0.047
2.77ArgLys: 2.77 ± 0.045
4.519ArgLeu: 4.519 ± 0.056
1.234ArgMet: 1.234 ± 0.027
2.413ArgAsn: 2.413 ± 0.045
1.672ArgPro: 1.672 ± 0.032
2.215ArgGln: 2.215 ± 0.043
2.058ArgArg: 2.058 ± 0.04
2.386ArgSer: 2.386 ± 0.045
2.314ArgThr: 2.314 ± 0.039
2.666ArgVal: 2.666 ± 0.041
0.68ArgTrp: 0.68 ± 0.021
2.156ArgTyr: 2.156 ± 0.041
0.0ArgXaa: 0.0 ± 0.0
Ser
4.746SerAla: 4.746 ± 0.064
0.515SerCys: 0.515 ± 0.021
2.912SerAsp: 2.912 ± 0.044
2.517SerGlu: 2.517 ± 0.044
3.097SerPhe: 3.097 ± 0.051
4.735SerGly: 4.735 ± 0.059
1.191SerHis: 1.191 ± 0.027
4.05SerIle: 4.05 ± 0.054
2.923SerLys: 2.923 ± 0.048
6.418SerLeu: 6.418 ± 0.086
1.389SerMet: 1.389 ± 0.033
2.998SerAsn: 2.998 ± 0.055
2.462SerPro: 2.462 ± 0.042
2.178SerGln: 2.178 ± 0.052
2.579SerArg: 2.579 ± 0.037
3.796SerSer: 3.796 ± 0.07
3.678SerThr: 3.678 ± 0.063
3.949SerVal: 3.949 ± 0.057
0.754SerTrp: 0.754 ± 0.028
2.524SerTyr: 2.524 ± 0.059
0.0SerXaa: 0.0 ± 0.0
Thr
5.746ThrAla: 5.746 ± 0.092
0.446ThrCys: 0.446 ± 0.018
3.341ThrAsp: 3.341 ± 0.058
2.533ThrGlu: 2.533 ± 0.044
2.809ThrPhe: 2.809 ± 0.048
5.055ThrGly: 5.055 ± 0.072
1.301ThrHis: 1.301 ± 0.033
4.064ThrIle: 4.064 ± 0.067
2.607ThrLys: 2.607 ± 0.047
6.331ThrLeu: 6.331 ± 0.083
1.103ThrMet: 1.103 ± 0.029
2.64ThrAsn: 2.64 ± 0.057
3.243ThrPro: 3.243 ± 0.072
2.241ThrGln: 2.241 ± 0.045
2.402ThrArg: 2.402 ± 0.046
3.49ThrSer: 3.49 ± 0.056
4.038ThrThr: 4.038 ± 0.091
4.465ThrVal: 4.465 ± 0.086
0.746ThrTrp: 0.746 ± 0.025
2.537ThrTyr: 2.537 ± 0.051
0.0ThrXaa: 0.0 ± 0.0
Val
5.499ValAla: 5.499 ± 0.07
0.626ValCys: 0.626 ± 0.024
3.167ValAsp: 3.167 ± 0.046
3.05ValGlu: 3.05 ± 0.056
3.028ValPhe: 3.028 ± 0.05
3.823ValGly: 3.823 ± 0.052
1.378ValHis: 1.378 ± 0.033
4.457ValIle: 4.457 ± 0.065
4.12ValLys: 4.12 ± 0.049
6.496ValLeu: 6.496 ± 0.074
1.711ValMet: 1.711 ± 0.037
3.447ValAsn: 3.447 ± 0.053
2.889ValPro: 2.889 ± 0.049
2.749ValGln: 2.749 ± 0.04
2.687ValArg: 2.687 ± 0.048
4.367ValSer: 4.367 ± 0.067
4.243ValThr: 4.243 ± 0.082
4.654ValVal: 4.654 ± 0.059
0.724ValTrp: 0.724 ± 0.021
2.575ValTyr: 2.575 ± 0.043
0.0ValXaa: 0.0 ± 0.0
Trp
0.841TrpAla: 0.841 ± 0.022
0.129TrpCys: 0.129 ± 0.009
0.652TrpAsp: 0.652 ± 0.023
0.702TrpGlu: 0.702 ± 0.024
0.524TrpPhe: 0.524 ± 0.022
0.791TrpGly: 0.791 ± 0.027
0.316TrpHis: 0.316 ± 0.017
0.697TrpIle: 0.697 ± 0.023
0.812TrpLys: 0.812 ± 0.024
1.359TrpLeu: 1.359 ± 0.033
0.404TrpMet: 0.404 ± 0.016
0.657TrpAsn: 0.657 ± 0.022
0.413TrpPro: 0.413 ± 0.019
0.727TrpGln: 0.727 ± 0.027
0.557TrpArg: 0.557 ± 0.021
0.675TrpSer: 0.675 ± 0.022
0.706TrpThr: 0.706 ± 0.021
0.736TrpVal: 0.736 ± 0.025
0.255TrpTrp: 0.255 ± 0.013
0.557TrpTyr: 0.557 ± 0.024
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.348TyrAla: 3.348 ± 0.052
0.363TyrCys: 0.363 ± 0.013
2.41TyrAsp: 2.41 ± 0.047
1.899TyrGlu: 1.899 ± 0.035
2.241TyrPhe: 2.241 ± 0.041
2.844TyrGly: 2.844 ± 0.053
1.01TyrHis: 1.01 ± 0.027
2.325TyrIle: 2.325 ± 0.042
2.361TyrLys: 2.361 ± 0.044
4.052TyrLeu: 4.052 ± 0.066
0.78TyrMet: 0.78 ± 0.024
2.515TyrAsn: 2.515 ± 0.048
1.813TyrPro: 1.813 ± 0.037
1.845TyrGln: 1.845 ± 0.04
1.931TyrArg: 1.931 ± 0.039
2.39TyrSer: 2.39 ± 0.049
2.749TyrThr: 2.749 ± 0.06
2.324TyrVal: 2.324 ± 0.04
0.592TyrTrp: 0.592 ± 0.021
1.985TyrTyr: 1.985 ± 0.046
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4204 proteins (1471284 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski