Amino acid dipepetide frequency for Panax notoginseng virus B

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.016AlaAla: 6.016 ± 0.55
1.337AlaCys: 1.337 ± 0.99
2.005AlaAsp: 2.005 ± 1.443
2.005AlaGlu: 2.005 ± 0.467
1.337AlaPhe: 1.337 ± 0.014
4.679AlaGly: 4.679 ± 1.416
1.337AlaHis: 1.337 ± 0.014
2.005AlaIle: 2.005 ± 1.484
3.342AlaLys: 3.342 ± 1.498
5.348AlaLeu: 5.348 ± 0.921
4.679AlaMet: 4.679 ± 2.488
3.342AlaAsn: 3.342 ± 1.43
0.0AlaPro: 0.0 ± 0.0
5.348AlaGln: 5.348 ± 0.921
6.016AlaArg: 6.016 ± 1.525
4.011AlaSer: 4.011 ± 1.017
6.684AlaThr: 6.684 ± 0.907
3.342AlaVal: 3.342 ± 0.522
2.674AlaTrp: 2.674 ± 0.948
4.011AlaTyr: 4.011 ± 1.017
0.0AlaXaa: 0.0 ± 0.0
Cys
0.668CysAla: 0.668 ± 0.481
0.0CysCys: 0.0 ± 0.0
0.668CysAsp: 0.668 ± 0.481
2.674CysGlu: 2.674 ± 0.027
0.0CysPhe: 0.0 ± 0.0
2.005CysGly: 2.005 ± 0.467
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.337CysLeu: 1.337 ± 0.014
0.0CysMet: 0.0 ± 0.0
0.668CysAsn: 0.668 ± 0.495
0.668CysPro: 0.668 ± 0.495
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
1.337CysSer: 1.337 ± 0.99
0.668CysThr: 0.668 ± 0.481
0.668CysVal: 0.668 ± 0.481
0.0CysTrp: 0.0 ± 0.0
0.668CysTyr: 0.668 ± 0.495
0.0CysXaa: 0.0 ± 0.0
Asp
2.674AspAla: 2.674 ± 1.924
2.005AspCys: 2.005 ± 1.443
7.353AspAsp: 7.353 ± 0.413
5.348AspGlu: 5.348 ± 1.897
4.011AspPhe: 4.011 ± 0.935
5.348AspGly: 5.348 ± 1.897
1.337AspHis: 1.337 ± 0.014
2.005AspIle: 2.005 ± 0.467
2.674AspLys: 2.674 ± 0.027
5.348AspLeu: 5.348 ± 0.921
2.005AspMet: 2.005 ± 0.508
2.005AspAsn: 2.005 ± 1.443
0.0AspPro: 0.0 ± 0.0
2.674AspGln: 2.674 ± 1.003
2.005AspArg: 2.005 ± 0.467
5.348AspSer: 5.348 ± 0.921
2.005AspThr: 2.005 ± 0.467
10.027AspVal: 10.027 ± 2.542
2.674AspTrp: 2.674 ± 0.027
3.342AspTyr: 3.342 ± 0.522
0.0AspXaa: 0.0 ± 0.0
Glu
5.348GluAla: 5.348 ± 0.055
1.337GluCys: 1.337 ± 0.014
4.011GluAsp: 4.011 ± 0.935
6.684GluGlu: 6.684 ± 2.996
3.342GluPhe: 3.342 ± 0.522
4.679GluGly: 4.679 ± 0.536
2.674GluHis: 2.674 ± 1.003
4.679GluIle: 4.679 ± 1.512
4.679GluLys: 4.679 ± 1.416
3.342GluLeu: 3.342 ± 0.522
0.668GluMet: 0.668 ± 0.495
2.674GluAsn: 2.674 ± 0.948
2.005GluPro: 2.005 ± 0.467
1.337GluGln: 1.337 ± 0.962
0.668GluArg: 0.668 ± 0.495
2.674GluSer: 2.674 ± 1.979
3.342GluThr: 3.342 ± 0.522
7.353GluVal: 7.353 ± 0.563
2.674GluTrp: 2.674 ± 0.027
1.337GluTyr: 1.337 ± 0.962
0.0GluXaa: 0.0 ± 0.0
Phe
2.005PheAla: 2.005 ± 1.484
0.668PheCys: 0.668 ± 0.495
4.679PheAsp: 4.679 ± 0.44
2.005PheGlu: 2.005 ± 0.508
1.337PhePhe: 1.337 ± 0.962
1.337PheGly: 1.337 ± 0.99
0.668PheHis: 0.668 ± 0.481
2.674PheIle: 2.674 ± 0.948
2.005PheLys: 2.005 ± 1.484
3.342PheLeu: 3.342 ± 1.498
1.337PheMet: 1.337 ± 0.99
3.342PheAsn: 3.342 ± 1.43
2.674PhePro: 2.674 ± 0.027
1.337PheGln: 1.337 ± 0.014
6.016PheArg: 6.016 ± 0.55
3.342PheSer: 3.342 ± 1.43
0.668PheThr: 0.668 ± 0.481
6.016PheVal: 6.016 ± 2.378
0.668PheTrp: 0.668 ± 0.481
1.337PheTyr: 1.337 ± 0.962
0.0PheXaa: 0.0 ± 0.0
Gly
4.679GlyAla: 4.679 ± 0.44
0.668GlyCys: 0.668 ± 0.481
2.005GlyAsp: 2.005 ± 0.467
5.348GlyGlu: 5.348 ± 2.007
0.668GlyPhe: 0.668 ± 0.481
4.679GlyGly: 4.679 ± 2.392
1.337GlyHis: 1.337 ± 0.962
6.684GlyIle: 6.684 ± 1.044
3.342GlyLys: 3.342 ± 2.405
5.348GlyLeu: 5.348 ± 2.873
2.674GlyMet: 2.674 ± 0.027
1.337GlyAsn: 1.337 ± 0.99
0.668GlyPro: 0.668 ± 0.495
1.337GlyGln: 1.337 ± 0.014
2.005GlyArg: 2.005 ± 0.467
4.011GlySer: 4.011 ± 0.935
3.342GlyThr: 3.342 ± 0.454
8.021GlyVal: 8.021 ± 1.87
0.668GlyTrp: 0.668 ± 0.495
2.674GlyTyr: 2.674 ± 0.948
0.0GlyXaa: 0.0 ± 0.0
His
1.337HisAla: 1.337 ± 0.014
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
3.342HisPhe: 3.342 ± 0.454
0.668HisGly: 0.668 ± 0.495
0.668HisHis: 0.668 ± 0.495
0.668HisIle: 0.668 ± 0.481
1.337HisLys: 1.337 ± 0.99
2.674HisLeu: 2.674 ± 1.003
2.005HisMet: 2.005 ± 0.467
1.337HisAsn: 1.337 ± 0.99
0.668HisPro: 0.668 ± 0.481
0.668HisGln: 0.668 ± 0.495
2.674HisArg: 2.674 ± 1.003
2.674HisSer: 2.674 ± 1.979
3.342HisThr: 3.342 ± 0.454
2.005HisVal: 2.005 ± 1.443
0.668HisTrp: 0.668 ± 0.481
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.342IleAla: 3.342 ± 0.522
0.0IleCys: 0.0 ± 0.0
3.342IleAsp: 3.342 ± 1.43
4.011IleGlu: 4.011 ± 1.017
2.005IlePhe: 2.005 ± 0.508
2.005IleGly: 2.005 ± 0.467
1.337IleHis: 1.337 ± 0.014
0.668IleIle: 0.668 ± 0.481
4.011IleLys: 4.011 ± 1.017
2.674IleLeu: 2.674 ± 0.027
0.0IleMet: 0.0 ± 0.0
3.342IleAsn: 3.342 ± 0.522
2.674IlePro: 2.674 ± 0.027
0.668IleGln: 0.668 ± 0.495
2.005IleArg: 2.005 ± 0.467
4.011IleSer: 4.011 ± 0.041
7.353IleThr: 7.353 ± 2.515
2.005IleVal: 2.005 ± 0.467
0.668IleTrp: 0.668 ± 0.495
2.005IleTyr: 2.005 ± 1.484
0.0IleXaa: 0.0 ± 0.0
Lys
1.337LysAla: 1.337 ± 0.99
0.668LysCys: 0.668 ± 0.495
4.679LysAsp: 4.679 ± 1.512
5.348LysGlu: 5.348 ± 2.007
2.674LysPhe: 2.674 ± 1.003
5.348LysGly: 5.348 ± 1.897
0.668LysHis: 0.668 ± 0.495
4.679LysIle: 4.679 ± 1.512
4.679LysLys: 4.679 ± 0.536
6.016LysLeu: 6.016 ± 0.426
2.005LysMet: 2.005 ± 0.467
1.337LysAsn: 1.337 ± 0.014
0.0LysPro: 0.0 ± 0.0
1.337LysGln: 1.337 ± 0.014
2.005LysArg: 2.005 ± 0.508
2.005LysSer: 2.005 ± 1.484
3.342LysThr: 3.342 ± 0.454
6.684LysVal: 6.684 ± 0.068
2.005LysTrp: 2.005 ± 0.467
2.674LysTyr: 2.674 ± 1.979
0.0LysXaa: 0.0 ± 0.0
Leu
4.011LeuAla: 4.011 ± 0.041
2.005LeuCys: 2.005 ± 0.467
6.016LeuAsp: 6.016 ± 1.402
2.674LeuGlu: 2.674 ± 0.027
4.679LeuPhe: 4.679 ± 1.512
2.674LeuGly: 2.674 ± 0.027
0.668LeuHis: 0.668 ± 0.481
3.342LeuIle: 3.342 ± 0.522
7.353LeuLys: 7.353 ± 1.539
5.348LeuLeu: 5.348 ± 0.055
3.342LeuMet: 3.342 ± 1.208
3.342LeuAsn: 3.342 ± 0.454
2.005LeuPro: 2.005 ± 1.443
2.674LeuGln: 2.674 ± 0.027
8.021LeuArg: 8.021 ± 0.894
6.016LeuSer: 6.016 ± 0.426
6.016LeuThr: 6.016 ± 0.426
5.348LeuVal: 5.348 ± 0.055
0.0LeuTrp: 0.0 ± 0.0
2.674LeuTyr: 2.674 ± 0.948
0.0LeuXaa: 0.0 ± 0.0
Met
1.337MetAla: 1.337 ± 0.014
0.0MetCys: 0.0 ± 0.0
2.005MetAsp: 2.005 ± 0.467
1.337MetGlu: 1.337 ± 0.962
4.011MetPhe: 4.011 ± 1.017
2.005MetGly: 2.005 ± 0.467
0.668MetHis: 0.668 ± 0.495
0.668MetIle: 0.668 ± 0.481
4.011MetLys: 4.011 ± 1.017
2.005MetLeu: 2.005 ± 0.508
2.674MetMet: 2.674 ± 0.027
1.337MetAsn: 1.337 ± 0.014
2.674MetPro: 2.674 ± 0.027
0.668MetGln: 0.668 ± 0.481
0.668MetArg: 0.668 ± 0.481
2.005MetSer: 2.005 ± 1.484
0.668MetThr: 0.668 ± 0.481
3.342MetVal: 3.342 ± 0.522
0.0MetTrp: 0.0 ± 0.0
3.342MetTyr: 3.342 ± 0.522
0.0MetXaa: 0.0 ± 0.0
Asn
4.011AsnAla: 4.011 ± 0.041
0.0AsnCys: 0.0 ± 0.0
3.342AsnAsp: 3.342 ± 1.43
3.342AsnGlu: 3.342 ± 0.454
2.005AsnPhe: 2.005 ± 0.467
2.005AsnGly: 2.005 ± 0.508
0.668AsnHis: 0.668 ± 0.481
2.674AsnIle: 2.674 ± 0.027
0.668AsnLys: 0.668 ± 0.495
3.342AsnLeu: 3.342 ± 0.454
3.342AsnMet: 3.342 ± 0.454
0.668AsnAsn: 0.668 ± 0.495
0.0AsnPro: 0.0 ± 0.0
0.668AsnGln: 0.668 ± 0.481
5.348AsnArg: 5.348 ± 0.055
0.0AsnSer: 0.0 ± 0.0
2.005AsnThr: 2.005 ± 0.467
2.674AsnVal: 2.674 ± 0.027
0.668AsnTrp: 0.668 ± 0.481
2.005AsnTyr: 2.005 ± 0.508
0.0AsnXaa: 0.0 ± 0.0
Pro
1.337ProAla: 1.337 ± 0.962
0.0ProCys: 0.0 ± 0.0
2.674ProAsp: 2.674 ± 1.924
2.674ProGlu: 2.674 ± 0.948
1.337ProPhe: 1.337 ± 0.962
3.342ProGly: 3.342 ± 1.43
0.0ProHis: 0.0 ± 0.0
0.668ProIle: 0.668 ± 0.495
0.0ProLys: 0.0 ± 0.0
3.342ProLeu: 3.342 ± 0.454
2.005ProMet: 2.005 ± 1.443
1.337ProAsn: 1.337 ± 0.014
2.005ProPro: 2.005 ± 0.467
0.668ProGln: 0.668 ± 0.495
0.668ProArg: 0.668 ± 0.495
1.337ProSer: 1.337 ± 0.014
2.674ProThr: 2.674 ± 0.948
2.005ProVal: 2.005 ± 0.508
0.668ProTrp: 0.668 ± 0.481
1.337ProTyr: 1.337 ± 0.014
0.0ProXaa: 0.0 ± 0.0
Gln
4.679GlnAla: 4.679 ± 0.536
0.668GlnCys: 0.668 ± 0.495
0.668GlnAsp: 0.668 ± 0.481
2.005GlnGlu: 2.005 ± 0.467
2.674GlnPhe: 2.674 ± 1.924
0.668GlnGly: 0.668 ± 0.481
2.005GlnHis: 2.005 ± 0.508
1.337GlnIle: 1.337 ± 0.014
0.0GlnLys: 0.0 ± 0.0
2.674GlnLeu: 2.674 ± 1.979
0.668GlnMet: 0.668 ± 0.481
1.337GlnAsn: 1.337 ± 0.014
0.668GlnPro: 0.668 ± 0.481
0.0GlnGln: 0.0 ± 0.0
1.337GlnArg: 1.337 ± 0.99
0.668GlnSer: 0.668 ± 0.481
0.668GlnThr: 0.668 ± 0.481
2.005GlnVal: 2.005 ± 0.508
0.0GlnTrp: 0.0 ± 0.0
2.674GlnTyr: 2.674 ± 1.979
0.0GlnXaa: 0.0 ± 0.0
Arg
8.021ArgAla: 8.021 ± 3.01
2.005ArgCys: 2.005 ± 0.508
3.342ArgAsp: 3.342 ± 0.522
3.342ArgGlu: 3.342 ± 0.454
4.679ArgPhe: 4.679 ± 0.44
5.348ArgGly: 5.348 ± 1.897
1.337ArgHis: 1.337 ± 0.014
3.342ArgIle: 3.342 ± 0.522
4.011ArgLys: 4.011 ± 0.041
7.353ArgLeu: 7.353 ± 1.388
2.674ArgMet: 2.674 ± 1.979
2.005ArgAsn: 2.005 ± 0.508
1.337ArgPro: 1.337 ± 0.99
0.668ArgGln: 0.668 ± 0.495
6.684ArgArg: 6.684 ± 1.044
3.342ArgSer: 3.342 ± 0.454
2.005ArgThr: 2.005 ± 0.508
2.674ArgVal: 2.674 ± 1.003
0.668ArgTrp: 0.668 ± 0.495
1.337ArgTyr: 1.337 ± 0.962
0.0ArgXaa: 0.0 ± 0.0
Ser
3.342SerAla: 3.342 ± 1.43
0.0SerCys: 0.0 ± 0.0
2.674SerAsp: 2.674 ± 1.003
2.674SerGlu: 2.674 ± 0.948
2.005SerPhe: 2.005 ± 0.467
2.674SerGly: 2.674 ± 1.003
3.342SerHis: 3.342 ± 0.522
2.674SerIle: 2.674 ± 1.003
4.011SerLys: 4.011 ± 0.935
1.337SerLeu: 1.337 ± 0.962
1.337SerMet: 1.337 ± 0.99
0.0SerAsn: 0.0 ± 0.0
2.005SerPro: 2.005 ± 1.443
2.674SerGln: 2.674 ± 1.003
6.016SerArg: 6.016 ± 0.426
6.016SerSer: 6.016 ± 1.402
4.679SerThr: 4.679 ± 0.536
9.358SerVal: 9.358 ± 3.999
0.668SerTrp: 0.668 ± 0.481
2.005SerTyr: 2.005 ± 0.467
0.0SerXaa: 0.0 ± 0.0
Thr
4.011ThrAla: 4.011 ± 0.935
0.0ThrCys: 0.0 ± 0.0
4.011ThrAsp: 4.011 ± 0.935
4.011ThrGlu: 4.011 ± 1.993
2.674ThrPhe: 2.674 ± 0.027
4.679ThrGly: 4.679 ± 1.416
2.674ThrHis: 2.674 ± 1.003
1.337ThrIle: 1.337 ± 0.99
3.342ThrLys: 3.342 ± 0.522
8.021ThrLeu: 8.021 ± 1.87
2.005ThrMet: 2.005 ± 0.467
3.342ThrAsn: 3.342 ± 0.522
4.011ThrPro: 4.011 ± 1.911
2.005ThrGln: 2.005 ± 0.508
6.684ThrArg: 6.684 ± 2.02
2.674ThrSer: 2.674 ± 0.948
2.674ThrThr: 2.674 ± 0.948
3.342ThrVal: 3.342 ± 1.43
0.0ThrTrp: 0.0 ± 0.0
1.337ThrTyr: 1.337 ± 0.962
0.0ThrXaa: 0.0 ± 0.0
Val
6.016ValAla: 6.016 ± 0.426
0.0ValCys: 0.0 ± 0.0
12.032ValAsp: 12.032 ± 1.099
4.679ValGlu: 4.679 ± 1.512
3.342ValPhe: 3.342 ± 0.522
4.679ValGly: 4.679 ± 0.536
3.342ValHis: 3.342 ± 1.498
3.342ValIle: 3.342 ± 0.454
6.016ValLys: 6.016 ± 2.501
6.016ValLeu: 6.016 ± 0.55
0.668ValMet: 0.668 ± 0.322
4.679ValAsn: 4.679 ± 1.416
4.011ValPro: 4.011 ± 1.911
0.668ValGln: 0.668 ± 0.495
5.348ValArg: 5.348 ± 0.055
4.679ValSer: 4.679 ± 1.416
8.021ValThr: 8.021 ± 0.082
3.342ValVal: 3.342 ± 1.498
1.337ValTrp: 1.337 ± 0.014
2.674ValTyr: 2.674 ± 0.027
0.0ValXaa: 0.0 ± 0.0
Trp
3.342TrpAla: 3.342 ± 0.522
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
2.674TrpGlu: 2.674 ± 0.027
0.0TrpPhe: 0.0 ± 0.0
1.337TrpGly: 1.337 ± 0.962
0.0TrpHis: 0.0 ± 0.0
0.668TrpIle: 0.668 ± 0.481
0.668TrpLys: 0.668 ± 0.481
0.668TrpLeu: 0.668 ± 0.481
0.0TrpMet: 0.0 ± 0.0
0.668TrpAsn: 0.668 ± 0.495
1.337TrpPro: 1.337 ± 0.962
1.337TrpGln: 1.337 ± 0.014
0.668TrpArg: 0.668 ± 0.495
0.668TrpSer: 0.668 ± 0.481
0.668TrpThr: 0.668 ± 0.481
1.337TrpVal: 1.337 ± 0.99
0.0TrpTrp: 0.0 ± 0.0
0.668TrpTyr: 0.668 ± 0.481
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.005TyrAla: 2.005 ± 1.484
0.668TyrCys: 0.668 ± 0.481
4.679TyrAsp: 4.679 ± 0.44
2.674TyrGlu: 2.674 ± 0.027
1.337TyrPhe: 1.337 ± 0.014
1.337TyrGly: 1.337 ± 0.99
2.005TyrHis: 2.005 ± 0.467
4.011TyrIle: 4.011 ± 0.041
3.342TyrLys: 3.342 ± 2.474
3.342TyrLeu: 3.342 ± 0.522
0.668TyrMet: 0.668 ± 0.481
1.337TyrAsn: 1.337 ± 0.962
0.668TyrPro: 0.668 ± 0.481
0.668TyrGln: 0.668 ± 0.481
1.337TyrArg: 1.337 ± 0.014
2.674TyrSer: 2.674 ± 1.003
2.005TyrThr: 2.005 ± 0.467
3.342TyrVal: 3.342 ± 0.454
0.0TyrTrp: 0.0 ± 0.0
0.668TyrTyr: 0.668 ± 0.481
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (1497 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski