Amino acid dipepetide frequency for Anditalea andensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.916AlaAla: 4.916 ± 0.07	0.536AlaCys: 0.536 ± 0.02	3.651AlaAsp: 3.651 ± 0.049	4.221AlaGlu: 4.221 ± 0.06	3.384AlaPhe: 3.384 ± 0.058	4.9AlaGly: 4.9 ± 0.066	1.294AlaHis: 1.294 ± 0.033	5.232AlaIle: 5.232 ± 0.071	3.778AlaLys: 3.778 ± 0.06	6.323AlaLeu: 6.323 ± 0.076	1.707AlaMet: 1.707 ± 0.036	3.098AlaAsn: 3.098 ± 0.053	2.197AlaPro: 2.197 ± 0.037	2.438AlaGln: 2.438 ± 0.043	2.475AlaArg: 2.475 ± 0.046	4.25AlaSer: 4.25 ± 0.064	3.232AlaThr: 3.232 ± 0.047	4.227AlaVal: 4.227 ± 0.063	0.727AlaTrp: 0.727 ± 0.025	2.779AlaTyr: 2.779 ± 0.042	0.0AlaXaa: 0.0 ± 0.0
Cys	0.39CysAla: 0.39 ± 0.018	0.087CysCys: 0.087 ± 0.009	0.361CysAsp: 0.361 ± 0.014	0.393CysGlu: 0.393 ± 0.018	0.382CysPhe: 0.382 ± 0.018	0.526CysGly: 0.526 ± 0.02	0.18CysHis: 0.18 ± 0.013	0.515CysIle: 0.515 ± 0.018	0.364CysLys: 0.364 ± 0.017	0.677CysLeu: 0.677 ± 0.024	0.167CysMet: 0.167 ± 0.01	0.326CysAsn: 0.326 ± 0.015	0.272CysPro: 0.272 ± 0.015	0.248CysGln: 0.248 ± 0.014	0.243CysArg: 0.243 ± 0.015	0.466CysSer: 0.466 ± 0.021	0.377CysThr: 0.377 ± 0.016	0.324CysVal: 0.324 ± 0.013	0.07CysTrp: 0.07 ± 0.007	0.235CysTyr: 0.235 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	3.298AspAla: 3.298 ± 0.05	0.314AspCys: 0.314 ± 0.013	2.627AspAsp: 2.627 ± 0.043	3.675AspGlu: 3.675 ± 0.054	3.426AspPhe: 3.426 ± 0.053	3.894AspGly: 3.894 ± 0.063	1.364AspHis: 1.364 ± 0.033	4.576AspIle: 4.576 ± 0.06	3.64AspLys: 3.64 ± 0.054	5.698AspLeu: 5.698 ± 0.066	1.389AspMet: 1.389 ± 0.032	2.769AspAsn: 2.769 ± 0.046	2.474AspPro: 2.474 ± 0.039	2.253AspGln: 2.253 ± 0.04	2.779AspArg: 2.779 ± 0.04	2.67AspSer: 2.67 ± 0.038	2.44AspThr: 2.44 ± 0.045	3.107AspVal: 3.107 ± 0.044	0.828AspTrp: 0.828 ± 0.026	2.541AspTyr: 2.541 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	4.603GluAla: 4.603 ± 0.06	0.271GluCys: 0.271 ± 0.015	3.779GluAsp: 3.779 ± 0.053	5.177GluGlu: 5.177 ± 0.07	2.727GluPhe: 2.727 ± 0.045	4.517GluGly: 4.517 ± 0.06	1.21GluHis: 1.21 ± 0.029	5.324GluIle: 5.324 ± 0.066	5.144GluLys: 5.144 ± 0.079	5.875GluLeu: 5.875 ± 0.066	1.868GluMet: 1.868 ± 0.032	4.164GluAsn: 4.164 ± 0.053	1.825GluPro: 1.825 ± 0.042	2.253GluGln: 2.253 ± 0.037	2.917GluArg: 2.917 ± 0.038	3.357GluSer: 3.357 ± 0.046	3.063GluThr: 3.063 ± 0.047	4.442GluVal: 4.442 ± 0.058	0.813GluTrp: 0.813 ± 0.025	2.35GluTyr: 2.35 ± 0.038	0.0GluXaa: 0.0 ± 0.0
Phe	2.887PheAla: 2.887 ± 0.049	0.401PheCys: 0.401 ± 0.016	3.193PheAsp: 3.193 ± 0.056	3.125PheGlu: 3.125 ± 0.041	2.687PhePhe: 2.687 ± 0.045	3.634PheGly: 3.634 ± 0.049	1.023PheHis: 1.023 ± 0.026	3.892PheIle: 3.892 ± 0.063	2.926PheLys: 2.926 ± 0.046	4.823PheLeu: 4.823 ± 0.068	1.25PheMet: 1.25 ± 0.031	2.87PheAsn: 2.87 ± 0.052	1.872PhePro: 1.872 ± 0.039	1.799PheGln: 1.799 ± 0.036	2.165PheArg: 2.165 ± 0.042	3.846PheSer: 3.846 ± 0.054	3.117PheThr: 3.117 ± 0.05	2.623PheVal: 2.623 ± 0.046	0.649PheTrp: 0.649 ± 0.024	2.227PheTyr: 2.227 ± 0.044	0.0PheXaa: 0.0 ± 0.0
Gly	4.458GlyAla: 4.458 ± 0.056	0.53GlyCys: 0.53 ± 0.024	3.529GlyAsp: 3.529 ± 0.045	4.199GlyGlu: 4.199 ± 0.058	3.81GlyPhe: 3.81 ± 0.05	5.09GlyGly: 5.09 ± 0.075	1.412GlyHis: 1.412 ± 0.032	5.802GlyIle: 5.802 ± 0.071	4.69GlyLys: 4.69 ± 0.075	6.418GlyLeu: 6.418 ± 0.074	2.003GlyMet: 2.003 ± 0.045	3.85GlyAsn: 3.85 ± 0.062	1.879GlyPro: 1.879 ± 0.035	2.509GlyGln: 2.509 ± 0.047	2.981GlyArg: 2.981 ± 0.05	4.326GlySer: 4.326 ± 0.054	3.881GlyThr: 3.881 ± 0.063	4.511GlyVal: 4.511 ± 0.059	0.955GlyTrp: 0.955 ± 0.029	3.093GlyTyr: 3.093 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	1.219HisAla: 1.219 ± 0.03	0.17HisCys: 0.17 ± 0.01	1.026HisAsp: 1.026 ± 0.029	1.203HisGlu: 1.203 ± 0.029	1.251HisPhe: 1.251 ± 0.03	1.307HisGly: 1.307 ± 0.03	0.715HisHis: 0.715 ± 0.027	1.644HisIle: 1.644 ± 0.036	1.149HisLys: 1.149 ± 0.028	2.274HisLeu: 2.274 ± 0.044	0.471HisMet: 0.471 ± 0.018	0.931HisAsn: 0.931 ± 0.025	1.183HisPro: 1.183 ± 0.028	0.922HisGln: 0.922 ± 0.03	0.9HisArg: 0.9 ± 0.023	1.203HisSer: 1.203 ± 0.028	1.116HisThr: 1.116 ± 0.027	1.046HisVal: 1.046 ± 0.03	0.287HisTrp: 0.287 ± 0.012	0.947HisTyr: 0.947 ± 0.028	0.0HisXaa: 0.0 ± 0.0
Ile	5.247IleAla: 5.247 ± 0.072	0.618IleCys: 0.618 ± 0.02	4.403IleAsp: 4.403 ± 0.056	4.83IleGlu: 4.83 ± 0.06	3.689IlePhe: 3.689 ± 0.054	5.45IleGly: 5.45 ± 0.068	1.639IleHis: 1.639 ± 0.033	6.011IleIle: 6.011 ± 0.076	5.108IleLys: 5.108 ± 0.079	7.276IleLeu: 7.276 ± 0.087	1.665IleMet: 1.665 ± 0.036	4.574IleAsn: 4.574 ± 0.056	3.382IlePro: 3.382 ± 0.048	2.743IleGln: 2.743 ± 0.042	3.353IleArg: 3.353 ± 0.052	5.846IleSer: 5.846 ± 0.055	4.269IleThr: 4.269 ± 0.064	4.022IleVal: 4.022 ± 0.05	0.88IleTrp: 0.88 ± 0.025	3.019IleTyr: 3.019 ± 0.048	0.0IleXaa: 0.0 ± 0.0
Lys	4.314LysAla: 4.314 ± 0.058	0.324LysCys: 0.324 ± 0.016	3.782LysAsp: 3.782 ± 0.056	5.052LysGlu: 5.052 ± 0.064	2.534LysPhe: 2.534 ± 0.043	4.263LysGly: 4.263 ± 0.062	1.251LysHis: 1.251 ± 0.031	5.221LysIle: 5.221 ± 0.059	4.94LysLys: 4.94 ± 0.075	5.592LysLeu: 5.592 ± 0.074	1.757LysMet: 1.757 ± 0.036	4.001LysAsn: 4.001 ± 0.059	2.179LysPro: 2.179 ± 0.042	1.983LysGln: 1.983 ± 0.04	2.485LysArg: 2.485 ± 0.048	4.017LysSer: 4.017 ± 0.058	3.24LysThr: 3.24 ± 0.054	4.142LysVal: 4.142 ± 0.057	0.769LysTrp: 0.769 ± 0.023	2.481LysTyr: 2.481 ± 0.043	0.0LysXaa: 0.0 ± 0.0
Leu	6.334LeuAla: 6.334 ± 0.08	0.655LeuCys: 0.655 ± 0.023	5.427LeuAsp: 5.427 ± 0.059	6.184LeuGlu: 6.184 ± 0.067	4.773LeuPhe: 4.773 ± 0.075	6.263LeuGly: 6.263 ± 0.076	1.887LeuHis: 1.887 ± 0.04	7.295LeuIle: 7.295 ± 0.094	6.426LeuLys: 6.426 ± 0.084	9.148LeuLeu: 9.148 ± 0.11	2.419LeuMet: 2.419 ± 0.04	5.269LeuAsn: 5.269 ± 0.067	4.147LeuPro: 4.147 ± 0.054	3.388LeuGln: 3.388 ± 0.057	3.797LeuArg: 3.797 ± 0.056	7.007LeuSer: 7.007 ± 0.073	4.973LeuThr: 4.973 ± 0.065	5.476LeuVal: 5.476 ± 0.071	0.978LeuTrp: 0.978 ± 0.029	3.456LeuTyr: 3.456 ± 0.046	0.0LeuXaa: 0.0 ± 0.0
Met	2.066MetAla: 2.066 ± 0.043	0.105MetCys: 0.105 ± 0.009	1.647MetAsp: 1.647 ± 0.034	1.832MetGlu: 1.832 ± 0.036	0.887MetPhe: 0.887 ± 0.026	1.947MetGly: 1.947 ± 0.044	0.458MetHis: 0.458 ± 0.02	1.788MetIle: 1.788 ± 0.036	1.962MetLys: 1.962 ± 0.033	2.177MetLeu: 2.177 ± 0.041	0.764MetMet: 0.764 ± 0.023	1.37MetAsn: 1.37 ± 0.028	1.046MetPro: 1.046 ± 0.026	0.821MetGln: 0.821 ± 0.022	1.055MetArg: 1.055 ± 0.028	1.434MetSer: 1.434 ± 0.029	1.281MetThr: 1.281 ± 0.031	1.857MetVal: 1.857 ± 0.035	0.228MetTrp: 0.228 ± 0.015	0.707MetTyr: 0.707 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.425AsnAla: 3.425 ± 0.053	0.34AsnCys: 0.34 ± 0.018	2.699AsnAsp: 2.699 ± 0.045	3.306AsnGlu: 3.306 ± 0.044	2.902AsnPhe: 2.902 ± 0.047	3.64AsnGly: 3.64 ± 0.066	1.195AsnHis: 1.195 ± 0.031	4.48AsnIle: 4.48 ± 0.059	3.3AsnLys: 3.3 ± 0.045	5.368AsnLeu: 5.368 ± 0.075	1.34AsnMet: 1.34 ± 0.029	2.964AsnAsn: 2.964 ± 0.054	2.827AsnPro: 2.827 ± 0.052	2.174AsnGln: 2.174 ± 0.04	2.594AsnArg: 2.594 ± 0.043	3.228AsnSer: 3.228 ± 0.049	2.834AsnThr: 2.834 ± 0.049	3.127AsnVal: 3.127 ± 0.053	0.725AsnTrp: 0.725 ± 0.024	2.489AsnTyr: 2.489 ± 0.045	0.0AsnXaa: 0.0 ± 0.0
Pro	2.455ProAla: 2.455 ± 0.038	0.198ProCys: 0.198 ± 0.011	2.616ProAsp: 2.616 ± 0.046	3.134ProGlu: 3.134 ± 0.051	2.074ProPhe: 2.074 ± 0.038	2.752ProGly: 2.752 ± 0.045	0.843ProHis: 0.843 ± 0.028	2.915ProIle: 2.915 ± 0.039	2.021ProLys: 2.021 ± 0.035	3.548ProLeu: 3.548 ± 0.054	0.926ProMet: 0.926 ± 0.026	2.06ProAsn: 2.06 ± 0.04	1.035ProPro: 1.035 ± 0.03	1.293ProGln: 1.293 ± 0.031	1.324ProArg: 1.324 ± 0.031	2.585ProSer: 2.585 ± 0.042	1.962ProThr: 1.962 ± 0.034	2.738ProVal: 2.738 ± 0.053	0.453ProTrp: 0.453 ± 0.017	1.698ProTyr: 1.698 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	2.32GlnAla: 2.32 ± 0.04	0.159GlnCys: 0.159 ± 0.01	1.819GlnAsp: 1.819 ± 0.037	2.616GlnGlu: 2.616 ± 0.046	1.685GlnPhe: 1.685 ± 0.034	2.174GlnGly: 2.174 ± 0.039	0.733GlnHis: 0.733 ± 0.024	2.655GlnIle: 2.655 ± 0.045	2.454GlnLys: 2.454 ± 0.037	3.506GlnLeu: 3.506 ± 0.053	1.006GlnMet: 1.006 ± 0.029	2.116GlnAsn: 2.116 ± 0.039	1.284GlnPro: 1.284 ± 0.032	1.509GlnGln: 1.509 ± 0.042	1.624GlnArg: 1.624 ± 0.031	2.076GlnSer: 2.076 ± 0.037	1.831GlnThr: 1.831 ± 0.032	2.402GlnVal: 2.402 ± 0.043	0.453GlnTrp: 0.453 ± 0.016	1.545GlnTyr: 1.545 ± 0.029	0.0GlnXaa: 0.0 ± 0.0
Arg	2.547ArgAla: 2.547 ± 0.043	0.189ArgCys: 0.189 ± 0.01	2.278ArgAsp: 2.278 ± 0.039	2.848ArgGlu: 2.848 ± 0.04	2.236ArgPhe: 2.236 ± 0.04	2.598ArgGly: 2.598 ± 0.043	0.838ArgHis: 0.838 ± 0.025	3.342ArgIle: 3.342 ± 0.046	2.908ArgLys: 2.908 ± 0.045	4.058ArgLeu: 4.058 ± 0.053	1.219ArgMet: 1.219 ± 0.028	2.509ArgAsn: 2.509 ± 0.044	1.601ArgPro: 1.601 ± 0.035	1.556ArgGln: 1.556 ± 0.033	1.831ArgArg: 1.831 ± 0.044	2.461ArgSer: 2.461 ± 0.048	2.215ArgThr: 2.215 ± 0.048	2.547ArgVal: 2.547 ± 0.047	0.587ArgTrp: 0.587 ± 0.021	1.925ArgTyr: 1.925 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	3.896SerAla: 3.896 ± 0.055	0.567SerCys: 0.567 ± 0.021	3.415SerAsp: 3.415 ± 0.049	3.78SerGlu: 3.78 ± 0.051	3.668SerPhe: 3.668 ± 0.05	4.942SerGly: 4.942 ± 0.06	1.319SerHis: 1.319 ± 0.031	5.064SerIle: 5.064 ± 0.055	3.793SerLys: 3.793 ± 0.048	6.402SerLeu: 6.402 ± 0.07	1.535SerMet: 1.535 ± 0.031	3.243SerAsn: 3.243 ± 0.049	2.623SerPro: 2.623 ± 0.042	2.221SerGln: 2.221 ± 0.04	2.725SerArg: 2.725 ± 0.038	4.307SerSer: 4.307 ± 0.06	3.335SerThr: 3.335 ± 0.055	3.638SerVal: 3.638 ± 0.053	0.761SerTrp: 0.761 ± 0.023	2.731SerTyr: 2.731 ± 0.044	0.0SerXaa: 0.0 ± 0.0
Thr	3.691ThrAla: 3.691 ± 0.055	0.333ThrCys: 0.333 ± 0.017	2.974ThrAsp: 2.974 ± 0.043	3.054ThrGlu: 3.054 ± 0.047	2.843ThrPhe: 2.843 ± 0.044	4.282ThrGly: 4.282 ± 0.062	1.103ThrHis: 1.103 ± 0.026	3.928ThrIle: 3.928 ± 0.064	2.737ThrLys: 2.737 ± 0.042	5.065ThrLeu: 5.065 ± 0.061	1.018ThrMet: 1.018 ± 0.026	2.473ThrAsn: 2.473 ± 0.046	2.306ThrPro: 2.306 ± 0.044	1.679ThrGln: 1.679 ± 0.034	1.982ThrArg: 1.982 ± 0.04	3.321ThrSer: 3.321 ± 0.048	2.686ThrThr: 2.686 ± 0.044	3.561ThrVal: 3.561 ± 0.055	0.651ThrTrp: 0.651 ± 0.021	2.31ThrTyr: 2.31 ± 0.044	0.0ThrXaa: 0.0 ± 0.0
Val	3.991ValAla: 3.991 ± 0.063	0.437ValCys: 0.437 ± 0.018	3.412ValAsp: 3.412 ± 0.055	3.781ValGlu: 3.781 ± 0.055	3.15ValPhe: 3.15 ± 0.045	3.999ValGly: 3.999 ± 0.053	1.213ValHis: 1.213 ± 0.027	4.669ValIle: 4.669 ± 0.056	3.81ValLys: 3.81 ± 0.053	5.78ValLeu: 5.78 ± 0.069	1.605ValMet: 1.605 ± 0.034	3.452ValAsn: 3.452 ± 0.057	2.411ValPro: 2.411 ± 0.045	1.968ValGln: 1.968 ± 0.035	2.498ValArg: 2.498 ± 0.044	4.226ValSer: 4.226 ± 0.057	3.266ValThr: 3.266 ± 0.049	3.774ValVal: 3.774 ± 0.061	0.649ValTrp: 0.649 ± 0.023	2.312ValTyr: 2.312 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	0.793TrpAla: 0.793 ± 0.023	0.085TrpCys: 0.085 ± 0.008	0.755TrpAsp: 0.755 ± 0.024	0.845TrpGlu: 0.845 ± 0.026	0.546TrpPhe: 0.546 ± 0.02	0.862TrpGly: 0.862 ± 0.024	0.259TrpHis: 0.259 ± 0.014	0.883TrpIle: 0.883 ± 0.029	0.799TrpLys: 0.799 ± 0.022	1.089TrpLeu: 1.089 ± 0.026	0.41TrpMet: 0.41 ± 0.021	0.66TrpAsn: 0.66 ± 0.02	0.398TrpPro: 0.398 ± 0.018	0.501TrpGln: 0.501 ± 0.021	0.514TrpArg: 0.514 ± 0.023	0.716TrpSer: 0.716 ± 0.023	0.637TrpThr: 0.637 ± 0.023	0.782TrpVal: 0.782 ± 0.023	0.205TrpTrp: 0.205 ± 0.012	0.471TrpTyr: 0.471 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.513TyrAla: 2.513 ± 0.042	0.283TyrCys: 0.283 ± 0.015	2.374TyrAsp: 2.374 ± 0.043	2.423TyrGlu: 2.423 ± 0.04	2.357TyrPhe: 2.357 ± 0.044	2.887TyrGly: 2.887 ± 0.041	1.028TyrHis: 1.028 ± 0.029	2.789TyrIle: 2.789 ± 0.041	2.377TyrLys: 2.377 ± 0.043	4.204TyrLeu: 4.204 ± 0.055	0.911TyrMet: 0.911 ± 0.026	2.257TyrAsn: 2.257 ± 0.043	1.689TyrPro: 1.689 ± 0.031	1.707TyrGln: 1.707 ± 0.037	2.053TyrArg: 2.053 ± 0.044	2.625TyrSer: 2.625 ± 0.039	2.241TyrThr: 2.241 ± 0.043	2.057TyrVal: 2.057 ± 0.035	0.541TyrTrp: 0.541 ± 0.021	1.867TyrTyr: 1.867 ± 0.041	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4341 proteins (1527423 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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