Amino acid dipepetide frequency for Tomato torrado virus (isolate Solanum lycopersicum/Spain/PRIToTV0301/-) (ToTV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.905AlaAla: 7.905 ± 0.887
0.847AlaCys: 0.847 ± 0.116
2.259AlaAsp: 2.259 ± 1.128
2.259AlaGlu: 2.259 ± 0.506
5.929AlaPhe: 5.929 ± 2.299
2.823AlaGly: 2.823 ± 1.181
2.259AlaHis: 2.259 ± 0.91
6.776AlaIle: 6.776 ± 0.213
3.953AlaLys: 3.953 ± 0.728
5.647AlaLeu: 5.647 ± 0.644
1.412AlaMet: 1.412 ± 0.546
1.976AlaAsn: 1.976 ± 0.312
2.541AlaPro: 2.541 ± 0.665
7.34AlaGln: 7.34 ± 1.798
3.106AlaArg: 3.106 ± 0.953
8.187AlaSer: 8.187 ± 1.002
4.8AlaThr: 4.8 ± 0.612
4.235AlaVal: 4.235 ± 0.573
0.565AlaTrp: 0.565 ± 0.137
3.106AlaTyr: 3.106 ± 0.991
0.0AlaXaa: 0.0 ± 0.0
Cys
2.259CysAla: 2.259 ± 0.91
0.282CysCys: 0.282 ± 0.168
1.129CysAsp: 1.129 ± 0.67
0.282CysGlu: 0.282 ± 0.168
0.847CysPhe: 0.847 ± 0.116
1.412CysGly: 1.412 ± 0.838
0.847CysHis: 0.847 ± 0.116
0.847CysIle: 0.847 ± 0.413
1.694CysLys: 1.694 ± 0.232
0.847CysLeu: 0.847 ± 0.413
0.0CysMet: 0.0 ± 0.0
1.412CysAsn: 1.412 ± 0.191
1.129CysPro: 1.129 ± 0.532
0.847CysGln: 0.847 ± 0.503
0.847CysArg: 0.847 ± 0.503
2.259CysSer: 2.259 ± 0.477
0.847CysThr: 0.847 ± 0.116
1.412CysVal: 1.412 ± 0.191
0.282CysTrp: 0.282 ± 0.168
1.129CysTyr: 1.129 ± 0.275
0.0CysXaa: 0.0 ± 0.0
Asp
3.67AspAla: 3.67 ± 1.321
0.847AspCys: 0.847 ± 0.116
2.823AspAsp: 2.823 ± 0.322
3.106AspGlu: 3.106 ± 1.156
2.259AspPhe: 2.259 ± 0.477
4.235AspGly: 4.235 ± 1.24
0.565AspHis: 0.565 ± 0.137
2.259AspIle: 2.259 ± 0.506
3.388AspLys: 3.388 ± 0.759
4.517AspLeu: 4.517 ± 1.404
2.259AspMet: 2.259 ± 0.91
1.412AspAsn: 1.412 ± 0.546
1.976AspPro: 1.976 ± 0.982
0.565AspGln: 0.565 ± 0.137
1.694AspArg: 1.694 ± 0.232
1.694AspSer: 1.694 ± 0.759
2.823AspThr: 2.823 ± 0.589
6.494AspVal: 6.494 ± 2.185
1.129AspTrp: 1.129 ± 0.253
1.976AspTyr: 1.976 ± 1.173
0.0AspXaa: 0.0 ± 0.0
Glu
4.8GluAla: 4.8 ± 2.743
1.129GluCys: 1.129 ± 0.275
2.541GluAsp: 2.541 ± 0.665
5.082GluGlu: 5.082 ± 2.175
2.541GluPhe: 2.541 ± 0.817
3.106GluGly: 3.106 ± 0.355
0.282GluHis: 0.282 ± 0.284
3.67GluIle: 3.67 ± 0.407
4.235GluLys: 4.235 ± 0.487
6.776GluLeu: 6.776 ± 0.761
1.412GluMet: 1.412 ± 0.978
3.388GluAsn: 3.388 ± 0.499
1.412GluPro: 1.412 ± 0.838
2.823GluGln: 2.823 ± 0.465
1.976GluArg: 1.976 ± 0.312
3.67GluSer: 3.67 ± 0.47
2.259GluThr: 2.259 ± 0.477
1.412GluVal: 1.412 ± 0.191
0.282GluTrp: 0.282 ± 0.168
1.129GluTyr: 1.129 ± 0.253
0.0GluXaa: 0.0 ± 0.0
Phe
3.106PheAla: 3.106 ± 0.39
1.694PheCys: 1.694 ± 0.232
3.67PheAsp: 3.67 ± 0.917
3.106PheGlu: 3.106 ± 0.39
2.259PhePhe: 2.259 ± 0.959
3.106PheGly: 3.106 ± 0.39
1.412PheHis: 1.412 ± 0.591
2.823PheIle: 2.823 ± 0.589
2.541PheLys: 2.541 ± 0.485
2.259PheLeu: 2.259 ± 0.91
1.129PheMet: 1.129 ± 0.275
2.259PheAsn: 2.259 ± 0.91
3.953PhePro: 3.953 ± 0.624
1.129PheGln: 1.129 ± 0.253
2.259PheArg: 2.259 ± 0.91
6.211PheSer: 6.211 ± 0.259
3.106PheThr: 3.106 ± 0.607
4.8PheVal: 4.8 ± 0.688
0.0PheTrp: 0.0 ± 0.0
1.412PheTyr: 1.412 ± 0.546
0.0PheXaa: 0.0 ± 0.0
Gly
5.364GlyAla: 5.364 ± 1.55
1.412GlyCys: 1.412 ± 0.838
2.541GlyAsp: 2.541 ± 0.442
2.541GlyGlu: 2.541 ± 0.665
3.953GlyPhe: 3.953 ± 2.346
3.67GlyGly: 3.67 ± 0.821
0.847GlyHis: 0.847 ± 0.602
4.235GlyIle: 4.235 ± 0.487
3.388GlyLys: 3.388 ± 0.568
3.953GlyLeu: 3.953 ± 0.728
2.541GlyMet: 2.541 ± 0.442
3.388GlyAsn: 3.388 ± 0.463
3.106GlyPro: 3.106 ± 0.355
1.976GlyGln: 1.976 ± 0.312
1.976GlyArg: 1.976 ± 0.356
4.235GlySer: 4.235 ± 1.363
4.235GlyThr: 4.235 ± 1.363
4.8GlyVal: 4.8 ± 0.588
0.847GlyTrp: 0.847 ± 0.615
1.694GlyTyr: 1.694 ± 0.578
0.0GlyXaa: 0.0 ± 0.0
His
1.129HisAla: 1.129 ± 0.67
0.282HisCys: 0.282 ± 0.168
0.847HisAsp: 0.847 ± 0.413
0.282HisGlu: 0.282 ± 0.284
1.412HisPhe: 1.412 ± 0.413
0.847HisGly: 0.847 ± 0.413
0.282HisHis: 0.282 ± 0.168
1.976HisIle: 1.976 ± 0.356
1.129HisLys: 1.129 ± 0.667
3.106HisLeu: 3.106 ± 0.953
0.847HisMet: 0.847 ± 0.413
1.412HisAsn: 1.412 ± 0.546
0.847HisPro: 0.847 ± 0.116
0.565HisGln: 0.565 ± 0.335
2.823HisArg: 2.823 ± 0.322
1.129HisSer: 1.129 ± 0.253
1.694HisThr: 1.694 ± 0.232
1.976HisVal: 1.976 ± 0.312
0.565HisTrp: 0.565 ± 0.137
1.129HisTyr: 1.129 ± 0.532
0.0HisXaa: 0.0 ± 0.0
Ile
4.517IleAla: 4.517 ± 0.69
2.259IleCys: 2.259 ± 0.424
2.541IleAsp: 2.541 ± 0.347
3.106IleGlu: 3.106 ± 0.576
3.106IlePhe: 3.106 ± 0.991
1.694IleGly: 1.694 ± 0.412
1.412IleHis: 1.412 ± 0.546
3.388IleIle: 3.388 ± 0.452
3.388IleLys: 3.388 ± 2.01
4.517IleLeu: 4.517 ± 0.69
1.412IleMet: 1.412 ± 0.546
2.541IleAsn: 2.541 ± 0.371
1.694IlePro: 1.694 ± 0.826
1.694IleGln: 1.694 ± 0.232
1.976IleArg: 1.976 ± 0.611
6.211IleSer: 6.211 ± 1.91
3.106IleThr: 3.106 ± 1.591
3.106IleVal: 3.106 ± 0.991
0.565IleTrp: 0.565 ± 0.137
2.259IleTyr: 2.259 ± 0.549
0.282IleXaa: 0.282 ± 0.168
Lys
1.976LysAla: 1.976 ± 0.312
1.412LysCys: 1.412 ± 0.413
2.823LysAsp: 2.823 ± 0.827
4.235LysGlu: 4.235 ± 1.083
1.412LysPhe: 1.412 ± 0.546
4.235LysGly: 4.235 ± 0.579
1.976LysHis: 1.976 ± 1.108
3.388LysIle: 3.388 ± 0.452
2.259LysLys: 2.259 ± 1.39
5.082LysLeu: 5.082 ± 1.624
1.694LysMet: 1.694 ± 0.44
3.106LysAsn: 3.106 ± 0.39
3.106LysPro: 3.106 ± 0.39
3.106LysGln: 3.106 ± 0.955
2.823LysArg: 2.823 ± 0.827
3.106LysSer: 3.106 ± 0.39
1.976LysThr: 1.976 ± 1.123
5.082LysVal: 5.082 ± 0.659
1.129LysTrp: 1.129 ± 0.275
1.129LysTyr: 1.129 ± 0.67
0.0LysXaa: 0.0 ± 0.0
Leu
4.517LeuAla: 4.517 ± 0.755
0.282LeuCys: 0.282 ± 0.284
4.235LeuAsp: 4.235 ± 1.021
7.058LeuGlu: 7.058 ± 1.863
4.517LeuPhe: 4.517 ± 0.569
5.082LeuGly: 5.082 ± 2.478
1.694LeuHis: 1.694 ± 0.232
4.8LeuIle: 4.8 ± 1.17
5.364LeuLys: 5.364 ± 1.08
8.47LeuLeu: 8.47 ± 2.043
1.129LeuMet: 1.129 ± 0.253
4.235LeuAsn: 4.235 ± 0.142
6.776LeuPro: 6.776 ± 1.177
3.388LeuGln: 3.388 ± 1.518
5.929LeuArg: 5.929 ± 0.626
7.905LeuSer: 7.905 ± 2.83
3.953LeuThr: 3.953 ± 0.728
7.905LeuVal: 7.905 ± 0.51
0.565LeuTrp: 0.565 ± 0.137
3.953LeuTyr: 3.953 ± 0.624
0.0LeuXaa: 0.0 ± 0.0
Met
1.694MetAla: 1.694 ± 1.005
0.0MetCys: 0.0 ± 0.0
1.694MetAsp: 1.694 ± 0.578
3.106MetGlu: 3.106 ± 0.39
1.412MetPhe: 1.412 ± 0.978
2.259MetGly: 2.259 ± 0.959
0.565MetHis: 0.565 ± 0.335
0.565MetIle: 0.565 ± 0.567
0.847MetLys: 0.847 ± 0.413
2.823MetLeu: 2.823 ± 0.827
1.412MetMet: 1.412 ± 0.191
1.412MetAsn: 1.412 ± 0.546
0.847MetPro: 0.847 ± 0.116
0.565MetGln: 0.565 ± 0.567
0.847MetArg: 0.847 ± 0.116
3.388MetSer: 3.388 ± 1.424
1.412MetThr: 1.412 ± 0.413
1.412MetVal: 1.412 ± 0.413
0.0MetTrp: 0.0 ± 0.0
1.129MetTyr: 1.129 ± 0.253
0.0MetXaa: 0.0 ± 0.0
Asn
3.106AsnAla: 3.106 ± 0.39
1.129AsnCys: 1.129 ± 0.253
1.412AsnAsp: 1.412 ± 0.51
2.823AsnGlu: 2.823 ± 0.465
1.976AsnPhe: 1.976 ± 1.173
2.541AsnGly: 2.541 ± 1.077
0.282AsnHis: 0.282 ± 0.284
3.953AsnIle: 3.953 ± 1.784
2.259AsnLys: 2.259 ± 0.284
3.388AsnLeu: 3.388 ± 1.652
1.412AsnMet: 1.412 ± 0.308
1.129AsnAsn: 1.129 ± 0.719
2.823AsnPro: 2.823 ± 0.827
0.847AsnGln: 0.847 ± 0.602
1.129AsnArg: 1.129 ± 0.275
1.976AsnSer: 1.976 ± 1.114
1.976AsnThr: 1.976 ± 0.424
3.106AsnVal: 3.106 ± 0.39
1.694AsnTrp: 1.694 ± 1.261
1.129AsnTyr: 1.129 ± 0.275
0.0AsnXaa: 0.0 ± 0.0
Pro
4.8ProAla: 4.8 ± 1.17
1.412ProCys: 1.412 ± 0.546
2.823ProAsp: 2.823 ± 0.465
0.847ProGlu: 0.847 ± 0.413
3.106ProPhe: 3.106 ± 0.576
2.541ProGly: 2.541 ± 0.854
2.259ProHis: 2.259 ± 0.284
1.694ProIle: 1.694 ± 0.541
1.694ProLys: 1.694 ± 1.203
3.388ProLeu: 3.388 ± 0.499
1.694ProMet: 1.694 ± 0.235
1.412ProAsn: 1.412 ± 0.191
1.129ProPro: 1.129 ± 0.275
1.976ProGln: 1.976 ± 1.295
1.694ProArg: 1.694 ± 0.826
4.517ProSer: 4.517 ± 0.753
3.106ProThr: 3.106 ± 0.364
3.106ProVal: 3.106 ± 0.991
0.282ProTrp: 0.282 ± 0.284
1.694ProTyr: 1.694 ± 0.578
0.0ProXaa: 0.0 ± 0.0
Gln
4.8GlnAla: 4.8 ± 0.315
1.412GlnCys: 1.412 ± 0.413
3.106GlnAsp: 3.106 ± 0.991
2.823GlnGlu: 2.823 ± 1.759
1.129GlnPhe: 1.129 ± 0.695
2.823GlnGly: 2.823 ± 0.827
0.847GlnHis: 0.847 ± 0.503
1.129GlnIle: 1.129 ± 0.275
1.412GlnLys: 1.412 ± 0.413
4.517GlnLeu: 4.517 ± 2.207
1.129GlnMet: 1.129 ± 0.253
1.412GlnAsn: 1.412 ± 0.753
2.259GlnPro: 2.259 ± 0.82
1.694GlnGln: 1.694 ± 0.486
3.106GlnArg: 3.106 ± 0.732
1.412GlnSer: 1.412 ± 0.191
1.694GlnThr: 1.694 ± 0.826
3.388GlnVal: 3.388 ± 1.194
1.129GlnTrp: 1.129 ± 0.667
1.694GlnTyr: 1.694 ± 0.232
0.0GlnXaa: 0.0 ± 0.0
Arg
2.823ArgAla: 2.823 ± 0.382
0.847ArgCys: 0.847 ± 0.116
3.67ArgAsp: 3.67 ± 0.47
1.694ArgGlu: 1.694 ± 1.005
1.694ArgPhe: 1.694 ± 0.826
1.976ArgGly: 1.976 ± 0.744
1.694ArgHis: 1.694 ± 0.578
1.129ArgIle: 1.129 ± 0.532
4.8ArgLys: 4.8 ± 0.588
6.211ArgLeu: 6.211 ± 1.944
0.847ArgMet: 0.847 ± 0.116
0.565ArgAsn: 0.565 ± 0.137
2.259ArgPro: 2.259 ± 0.284
1.694ArgGln: 1.694 ± 0.412
1.694ArgArg: 1.694 ± 0.578
2.823ArgSer: 2.823 ± 1.181
1.412ArgThr: 1.412 ± 0.413
3.106ArgVal: 3.106 ± 0.576
0.565ArgTrp: 0.565 ± 0.335
1.976ArgTyr: 1.976 ± 0.312
0.0ArgXaa: 0.0 ± 0.0
Ser
6.211SerAla: 6.211 ± 0.259
0.565SerCys: 0.565 ± 0.335
2.541SerAsp: 2.541 ± 0.371
3.953SerGlu: 3.953 ± 0.654
5.647SerPhe: 5.647 ± 0.099
6.494SerGly: 6.494 ± 2.522
1.976SerHis: 1.976 ± 0.356
4.517SerIle: 4.517 ± 0.598
5.364SerLys: 5.364 ± 0.635
6.494SerLeu: 6.494 ± 1.389
3.388SerMet: 3.388 ± 0.499
4.235SerAsn: 4.235 ± 0.831
1.976SerPro: 1.976 ± 0.424
3.953SerGln: 3.953 ± 1.237
3.106SerArg: 3.106 ± 0.355
10.446SerSer: 10.446 ± 1.949
4.235SerThr: 4.235 ± 0.573
5.647SerVal: 5.647 ± 3.288
1.129SerTrp: 1.129 ± 0.532
1.412SerTyr: 1.412 ± 0.191
0.0SerXaa: 0.0 ± 0.0
Thr
4.235ThrAla: 4.235 ± 1.654
1.129ThrCys: 1.129 ± 0.275
1.694ThrAsp: 1.694 ± 0.578
2.259ThrGlu: 2.259 ± 0.82
2.259ThrPhe: 2.259 ± 0.506
3.953ThrGly: 3.953 ± 1.533
2.259ThrHis: 2.259 ± 0.284
2.259ThrIle: 2.259 ± 0.284
2.823ThrLys: 2.823 ± 0.382
6.776ThrLeu: 6.776 ± 0.512
1.129ThrMet: 1.129 ± 0.275
1.694ThrAsn: 1.694 ± 1.261
1.694ThrPro: 1.694 ± 0.412
1.694ThrGln: 1.694 ± 0.541
2.259ThrArg: 2.259 ± 1.064
5.647ThrSer: 5.647 ± 0.983
3.953ThrThr: 3.953 ± 0.728
3.953ThrVal: 3.953 ± 0.5
1.412ThrTrp: 1.412 ± 0.753
1.976ThrTyr: 1.976 ± 0.312
0.0ThrXaa: 0.0 ± 0.0
Val
7.905ValAla: 7.905 ± 0.458
2.541ValCys: 2.541 ± 0.854
4.517ValAsp: 4.517 ± 1.039
3.953ValGlu: 3.953 ± 0.5
3.388ValPhe: 3.388 ± 0.452
3.67ValGly: 3.67 ± 0.917
1.976ValHis: 1.976 ± 0.982
2.823ValIle: 2.823 ± 0.687
2.259ValLys: 2.259 ± 1.658
9.599ValLeu: 9.599 ± 0.71
1.694ValMet: 1.694 ± 0.412
1.129ValAsn: 1.129 ± 0.253
3.67ValPro: 3.67 ± 0.821
4.8ValGln: 4.8 ± 0.612
3.388ValArg: 3.388 ± 0.463
4.8ValSer: 4.8 ± 0.838
5.082ValThr: 5.082 ± 1.807
5.364ValVal: 5.364 ± 1.899
0.565ValTrp: 0.565 ± 0.567
1.129ValTyr: 1.129 ± 0.253
0.0ValXaa: 0.0 ± 0.0
Trp
0.847TrpAla: 0.847 ± 0.413
0.565TrpCys: 0.565 ± 0.137
1.129TrpAsp: 1.129 ± 0.695
0.282TrpGlu: 0.282 ± 0.168
0.282TrpPhe: 0.282 ± 0.168
0.565TrpGly: 0.565 ± 0.137
0.0TrpHis: 0.0 ± 0.0
0.282TrpIle: 0.282 ± 0.168
0.847TrpLys: 0.847 ± 0.851
1.129TrpLeu: 1.129 ± 0.67
0.282TrpMet: 0.282 ± 0.168
0.282TrpAsn: 0.282 ± 0.284
0.565TrpPro: 0.565 ± 0.606
0.565TrpGln: 0.565 ± 0.606
0.282TrpArg: 0.282 ± 0.168
1.412TrpSer: 1.412 ± 0.546
1.129TrpThr: 1.129 ± 0.719
2.259TrpVal: 2.259 ± 1.128
0.282TrpTrp: 0.282 ± 0.284
1.129TrpTyr: 1.129 ± 0.253
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.259TyrAla: 2.259 ± 0.91
0.565TyrCys: 0.565 ± 0.335
1.694TyrAsp: 1.694 ± 0.412
1.129TyrGlu: 1.129 ± 0.275
3.106TyrPhe: 3.106 ± 0.39
3.67TyrGly: 3.67 ± 1.089
0.565TyrHis: 0.565 ± 0.335
2.259TyrIle: 2.259 ± 0.506
1.412TyrLys: 1.412 ± 0.191
2.259TyrLeu: 2.259 ± 0.424
0.282TyrMet: 0.282 ± 0.168
1.976TyrAsn: 1.976 ± 0.356
1.412TyrPro: 1.412 ± 0.191
1.694TyrGln: 1.694 ± 0.578
0.565TyrArg: 0.565 ± 0.335
2.259TyrSer: 2.259 ± 0.284
2.259TyrThr: 2.259 ± 0.284
1.694TyrVal: 1.694 ± 0.578
1.129TyrTrp: 1.129 ± 0.253
0.847TyrTyr: 0.847 ± 0.413
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.282XaaHis: 0.282 ± 0.168
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (3543 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski