Amino acid dipepetide frequency for Prevotella sp. oral taxon 317 str. F0108

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.396AlaAla: 6.396 ± 0.097	1.087AlaCys: 1.087 ± 0.03	4.757AlaAsp: 4.757 ± 0.077	4.833AlaGlu: 4.833 ± 0.076	3.678AlaPhe: 3.678 ± 0.07	4.833AlaGly: 4.833 ± 0.075	1.499AlaHis: 1.499 ± 0.039	4.551AlaIle: 4.551 ± 0.088	4.793AlaLys: 4.793 ± 0.075	7.544AlaLeu: 7.544 ± 0.094	2.13AlaMet: 2.13 ± 0.05	4.164AlaAsn: 4.164 ± 0.071	2.556AlaPro: 2.556 ± 0.054	3.576AlaGln: 3.576 ± 0.064	3.5AlaArg: 3.5 ± 0.071	4.119AlaSer: 4.119 ± 0.065	4.597AlaThr: 4.597 ± 0.079	4.922AlaVal: 4.922 ± 0.075	0.905AlaTrp: 0.905 ± 0.032	3.353AlaTyr: 3.353 ± 0.064	0.0AlaXaa: 0.0 ± 0.0
Cys	0.934CysAla: 0.934 ± 0.031	0.197CysCys: 0.197 ± 0.014	0.641CysAsp: 0.641 ± 0.025	0.629CysGlu: 0.629 ± 0.026	0.598CysPhe: 0.598 ± 0.027	0.987CysGly: 0.987 ± 0.038	0.299CysHis: 0.299 ± 0.018	0.789CysIle: 0.789 ± 0.024	0.728CysLys: 0.728 ± 0.027	1.167CysLeu: 1.167 ± 0.039	0.31CysMet: 0.31 ± 0.018	0.628CysAsn: 0.628 ± 0.026	0.491CysPro: 0.491 ± 0.024	0.372CysGln: 0.372 ± 0.02	0.6CysArg: 0.6 ± 0.027	0.651CysSer: 0.651 ± 0.025	0.64CysThr: 0.64 ± 0.025	0.791CysVal: 0.791 ± 0.027	0.166CysTrp: 0.166 ± 0.012	0.502CysTyr: 0.502 ± 0.022	0.0CysXaa: 0.0 ± 0.0
Asp	4.461AspAla: 4.461 ± 0.062	0.627AspCys: 0.627 ± 0.026	2.898AspAsp: 2.898 ± 0.058	3.904AspGlu: 3.904 ± 0.072	2.937AspPhe: 2.937 ± 0.055	4.268AspGly: 4.268 ± 0.086	0.845AspHis: 0.845 ± 0.027	3.616AspIle: 3.616 ± 0.065	4.012AspLys: 4.012 ± 0.064	4.695AspLeu: 4.695 ± 0.076	1.509AspMet: 1.509 ± 0.039	3.126AspAsn: 3.126 ± 0.067	1.818AspPro: 1.818 ± 0.05	1.221AspGln: 1.221 ± 0.036	2.423AspArg: 2.423 ± 0.052	2.907AspSer: 2.907 ± 0.068	2.836AspThr: 2.836 ± 0.059	4.011AspVal: 4.011 ± 0.063	0.824AspTrp: 0.824 ± 0.029	2.648AspTyr: 2.648 ± 0.052	0.0AspXaa: 0.0 ± 0.0
Glu	4.081GluAla: 4.081 ± 0.085	0.584GluCys: 0.584 ± 0.026	2.889GluAsp: 2.889 ± 0.06	4.252GluGlu: 4.252 ± 0.086	2.007GluPhe: 2.007 ± 0.047	3.866GluGly: 3.866 ± 0.066	1.287GluHis: 1.287 ± 0.037	3.439GluIle: 3.439 ± 0.064	4.259GluLys: 4.259 ± 0.079	5.519GluLeu: 5.519 ± 0.087	1.916GluMet: 1.916 ± 0.041	3.093GluAsn: 3.093 ± 0.053	1.837GluPro: 1.837 ± 0.044	2.795GluGln: 2.795 ± 0.055	3.669GluArg: 3.669 ± 0.057	2.709GluSer: 2.709 ± 0.06	3.527GluThr: 3.527 ± 0.059	4.098GluVal: 4.098 ± 0.062	0.762GluTrp: 0.762 ± 0.029	2.33GluTyr: 2.33 ± 0.044	0.0GluXaa: 0.0 ± 0.0
Phe	3.627PheAla: 3.627 ± 0.067	0.682PheCys: 0.682 ± 0.031	2.827PheAsp: 2.827 ± 0.058	2.399PheGlu: 2.399 ± 0.052	2.187PhePhe: 2.187 ± 0.055	3.245PheGly: 3.245 ± 0.063	0.835PheHis: 0.835 ± 0.028	2.574PheIle: 2.574 ± 0.052	2.699PheLys: 2.699 ± 0.054	3.47PheLeu: 3.47 ± 0.071	1.213PheMet: 1.213 ± 0.029	2.642PheAsn: 2.642 ± 0.047	1.566PhePro: 1.566 ± 0.042	1.085PheGln: 1.085 ± 0.036	2.032PheArg: 2.032 ± 0.047	3.129PheSer: 3.129 ± 0.06	2.763PheThr: 2.763 ± 0.054	3.372PheVal: 3.372 ± 0.069	0.551PheTrp: 0.551 ± 0.026	1.933PheTyr: 1.933 ± 0.046	0.0PheXaa: 0.0 ± 0.0
Gly	4.593GlyAla: 4.593 ± 0.08	0.945GlyCys: 0.945 ± 0.031	3.582GlyAsp: 3.582 ± 0.064	4.084GlyGlu: 4.084 ± 0.062	3.151GlyPhe: 3.151 ± 0.061	4.857GlyGly: 4.857 ± 0.092	1.404GlyHis: 1.404 ± 0.035	4.426GlyIle: 4.426 ± 0.066	5.573GlyLys: 5.573 ± 0.08	5.868GlyLeu: 5.868 ± 0.084	2.176GlyMet: 2.176 ± 0.055	3.736GlyAsn: 3.736 ± 0.073	1.287GlyPro: 1.287 ± 0.033	2.422GlyGln: 2.422 ± 0.049	3.329GlyArg: 3.329 ± 0.064	3.849GlySer: 3.849 ± 0.076	4.135GlyThr: 4.135 ± 0.077	5.068GlyVal: 5.068 ± 0.081	0.985GlyTrp: 0.985 ± 0.034	3.264GlyTyr: 3.264 ± 0.064	0.0GlyXaa: 0.0 ± 0.0
His	1.555HisAla: 1.555 ± 0.039	0.302HisCys: 0.302 ± 0.018	0.986HisAsp: 0.986 ± 0.03	1.029HisGlu: 1.029 ± 0.031	1.187HisPhe: 1.187 ± 0.034	1.377HisGly: 1.377 ± 0.042	0.524HisHis: 0.524 ± 0.023	1.397HisIle: 1.397 ± 0.04	1.073HisLys: 1.073 ± 0.034	1.883HisLeu: 1.883 ± 0.049	0.345HisMet: 0.345 ± 0.019	1.128HisAsn: 1.128 ± 0.034	1.021HisPro: 1.021 ± 0.03	0.706HisGln: 0.706 ± 0.026	1.054HisArg: 1.054 ± 0.032	1.078HisSer: 1.078 ± 0.038	1.106HisThr: 1.106 ± 0.034	1.297HisVal: 1.297 ± 0.038	0.273HisTrp: 0.273 ± 0.015	1.015HisTyr: 1.015 ± 0.032	0.0HisXaa: 0.0 ± 0.0
Ile	4.851IleAla: 4.851 ± 0.088	0.724IleCys: 0.724 ± 0.028	4.066IleAsp: 4.066 ± 0.059	3.764IleGlu: 3.764 ± 0.067	2.134IlePhe: 2.134 ± 0.054	3.902IleGly: 3.902 ± 0.071	1.004IleHis: 1.004 ± 0.029	3.378IleIle: 3.378 ± 0.077	3.754IleLys: 3.754 ± 0.07	4.497IleLeu: 4.497 ± 0.078	1.345IleMet: 1.345 ± 0.032	3.199IleAsn: 3.199 ± 0.061	2.449IlePro: 2.449 ± 0.049	1.655IleGln: 1.655 ± 0.04	2.897IleArg: 2.897 ± 0.051	3.672IleSer: 3.672 ± 0.062	3.746IleThr: 3.746 ± 0.06	4.256IleVal: 4.256 ± 0.066	0.559IleTrp: 0.559 ± 0.026	2.322IleTyr: 2.322 ± 0.043	0.0IleXaa: 0.0 ± 0.0
Lys	5.495LysAla: 5.495 ± 0.094	0.528LysCys: 0.528 ± 0.023	3.918LysAsp: 3.918 ± 0.073	4.523LysGlu: 4.523 ± 0.081	2.141LysPhe: 2.141 ± 0.048	4.742LysGly: 4.742 ± 0.077	1.347LysHis: 1.347 ± 0.035	3.222LysIle: 3.222 ± 0.06	4.434LysLys: 4.434 ± 0.085	5.562LysLeu: 5.562 ± 0.077	2.057LysMet: 2.057 ± 0.044	3.157LysAsn: 3.157 ± 0.065	2.446LysPro: 2.446 ± 0.047	2.815LysGln: 2.815 ± 0.056	3.703LysArg: 3.703 ± 0.058	3.324LysSer: 3.324 ± 0.063	3.729LysThr: 3.729 ± 0.071	4.305LysVal: 4.305 ± 0.06	0.848LysTrp: 0.848 ± 0.029	2.632LysTyr: 2.632 ± 0.053	0.0LysXaa: 0.0 ± 0.0
Leu	7.227LeuAla: 7.227 ± 0.09	1.329LeuCys: 1.329 ± 0.039	4.667LeuAsp: 4.667 ± 0.072	4.371LeuGlu: 4.371 ± 0.069	4.329LeuPhe: 4.329 ± 0.088	5.981LeuGly: 5.981 ± 0.091	1.949LeuHis: 1.949 ± 0.043	4.488LeuIle: 4.488 ± 0.079	5.613LeuLys: 5.613 ± 0.087	8.666LeuLeu: 8.666 ± 0.142	2.444LeuMet: 2.444 ± 0.05	5.022LeuAsn: 5.022 ± 0.093	4.236LeuPro: 4.236 ± 0.072	3.597LeuGln: 3.597 ± 0.065	4.889LeuArg: 4.889 ± 0.074	6.586LeuSer: 6.586 ± 0.103	5.461LeuThr: 5.461 ± 0.075	5.711LeuVal: 5.711 ± 0.087	1.093LeuTrp: 1.093 ± 0.039	3.573LeuTyr: 3.573 ± 0.06	0.0LeuXaa: 0.0 ± 0.0
Met	2.475MetAla: 2.475 ± 0.059	0.238MetCys: 0.238 ± 0.015	1.342MetAsp: 1.342 ± 0.039	1.54MetGlu: 1.54 ± 0.045	1.035MetPhe: 1.035 ± 0.034	1.952MetGly: 1.952 ± 0.043	0.55MetHis: 0.55 ± 0.023	1.232MetIle: 1.232 ± 0.035	2.214MetLys: 2.214 ± 0.042	2.653MetLeu: 2.653 ± 0.049	0.873MetMet: 0.873 ± 0.031	1.499MetAsn: 1.499 ± 0.036	1.462MetPro: 1.462 ± 0.048	1.313MetGln: 1.313 ± 0.038	1.564MetArg: 1.564 ± 0.042	1.483MetSer: 1.483 ± 0.038	1.262MetThr: 1.262 ± 0.033	1.79MetVal: 1.79 ± 0.04	0.234MetTrp: 0.234 ± 0.017	0.802MetTyr: 0.802 ± 0.029	0.0MetXaa: 0.0 ± 0.0
Asn	4.32AsnAla: 4.32 ± 0.067	0.476AsnCys: 0.476 ± 0.026	3.064AsnAsp: 3.064 ± 0.064	3.155AsnGlu: 3.155 ± 0.056	2.201AsnPhe: 2.201 ± 0.048	4.172AsnGly: 4.172 ± 0.082	0.992AsnHis: 0.992 ± 0.032	3.518AsnIle: 3.518 ± 0.058	3.488AsnLys: 3.488 ± 0.065	4.451AsnLeu: 4.451 ± 0.071	1.32AsnMet: 1.32 ± 0.038	3.004AsnAsn: 3.004 ± 0.061	2.485AsnPro: 2.485 ± 0.056	1.628AsnGln: 1.628 ± 0.043	2.619AsnArg: 2.619 ± 0.055	2.726AsnSer: 2.726 ± 0.056	3.047AsnThr: 3.047 ± 0.058	3.719AsnVal: 3.719 ± 0.065	0.632AsnTrp: 0.632 ± 0.024	2.333AsnTyr: 2.333 ± 0.053	0.0AsnXaa: 0.0 ± 0.0
Pro	2.705ProAla: 2.705 ± 0.055	0.353ProCys: 0.353 ± 0.021	2.314ProAsp: 2.314 ± 0.047	2.601ProGlu: 2.601 ± 0.057	1.926ProPhe: 1.926 ± 0.044	2.153ProGly: 2.153 ± 0.05	0.854ProHis: 0.854 ± 0.03	2.328ProIle: 2.328 ± 0.053	2.226ProLys: 2.226 ± 0.046	3.507ProLeu: 3.507 ± 0.061	0.984ProMet: 0.984 ± 0.032	2.138ProAsn: 2.138 ± 0.045	0.9ProPro: 0.9 ± 0.028	1.805ProGln: 1.805 ± 0.045	1.516ProArg: 1.516 ± 0.043	2.303ProSer: 2.303 ± 0.054	2.681ProThr: 2.681 ± 0.053	2.459ProVal: 2.459 ± 0.052	0.453ProTrp: 0.453 ± 0.023	1.758ProTyr: 1.758 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	2.994GlnAla: 2.994 ± 0.061	0.397GlnCys: 0.397 ± 0.02	1.482GlnAsp: 1.482 ± 0.039	2.001GlnGlu: 2.001 ± 0.043	1.48GlnPhe: 1.48 ± 0.037	2.51GlnGly: 2.51 ± 0.055	0.855GlnHis: 0.855 ± 0.036	1.944GlnIle: 1.944 ± 0.05	2.358GlnLys: 2.358 ± 0.054	3.966GlnLeu: 3.966 ± 0.073	1.183GlnMet: 1.183 ± 0.033	1.766GlnAsn: 1.766 ± 0.05	1.561GlnPro: 1.561 ± 0.041	2.035GlnGln: 2.035 ± 0.061	2.349GlnArg: 2.349 ± 0.052	2.04GlnSer: 2.04 ± 0.043	2.423GlnThr: 2.423 ± 0.049	2.243GlnVal: 2.243 ± 0.055	0.633GlnTrp: 0.633 ± 0.024	1.517GlnTyr: 1.517 ± 0.039	0.0GlnXaa: 0.0 ± 0.0
Arg	3.309ArgAla: 3.309 ± 0.065	0.555ArgCys: 0.555 ± 0.025	2.343ArgAsp: 2.343 ± 0.054	2.859ArgGlu: 2.859 ± 0.064	2.418ArgPhe: 2.418 ± 0.05	2.971ArgGly: 2.971 ± 0.055	1.263ArgHis: 1.263 ± 0.042	3.376ArgIle: 3.376 ± 0.054	3.334ArgLys: 3.334 ± 0.063	5.123ArgLeu: 5.123 ± 0.087	1.679ArgMet: 1.679 ± 0.038	2.794ArgAsn: 2.794 ± 0.052	1.793ArgPro: 1.793 ± 0.043	2.231ArgGln: 2.231 ± 0.049	2.703ArgArg: 2.703 ± 0.054	2.46ArgSer: 2.46 ± 0.047	3.039ArgThr: 3.039 ± 0.049	3.081ArgVal: 3.081 ± 0.054	0.826ArgTrp: 0.826 ± 0.031	2.566ArgTyr: 2.566 ± 0.05	0.0ArgXaa: 0.0 ± 0.0
Ser	4.418SerAla: 4.418 ± 0.073	0.739SerCys: 0.739 ± 0.03	2.893SerAsp: 2.893 ± 0.059	2.948SerGlu: 2.948 ± 0.061	2.97SerPhe: 2.97 ± 0.064	4.005SerGly: 4.005 ± 0.073	1.178SerHis: 1.178 ± 0.031	3.607SerIle: 3.607 ± 0.066	3.486SerLys: 3.486 ± 0.067	5.743SerLeu: 5.743 ± 0.083	1.498SerMet: 1.498 ± 0.039	2.724SerAsn: 2.724 ± 0.055	2.391SerPro: 2.391 ± 0.046	1.96SerGln: 1.96 ± 0.049	2.716SerArg: 2.716 ± 0.05	3.5SerSer: 3.5 ± 0.077	3.295SerThr: 3.295 ± 0.06	4.204SerVal: 4.204 ± 0.07	0.76SerTrp: 0.76 ± 0.03	2.588SerTyr: 2.588 ± 0.064	0.0SerXaa: 0.0 ± 0.0
Thr	4.746ThrAla: 4.746 ± 0.067	0.623ThrCys: 0.623 ± 0.027	3.504ThrAsp: 3.504 ± 0.064	2.97ThrGlu: 2.97 ± 0.052	2.923ThrPhe: 2.923 ± 0.058	4.07ThrGly: 4.07 ± 0.074	1.186ThrHis: 1.186 ± 0.036	3.757ThrIle: 3.757 ± 0.063	3.23ThrLys: 3.23 ± 0.063	6.006ThrLeu: 6.006 ± 0.081	1.361ThrMet: 1.361 ± 0.042	2.853ThrAsn: 2.853 ± 0.055	2.967ThrPro: 2.967 ± 0.065	2.029ThrGln: 2.029 ± 0.048	2.636ThrArg: 2.636 ± 0.05	3.407ThrSer: 3.407 ± 0.062	3.782ThrThr: 3.782 ± 0.074	3.545ThrVal: 3.545 ± 0.069	0.749ThrTrp: 0.749 ± 0.03	2.589ThrTyr: 2.589 ± 0.057	0.0ThrXaa: 0.0 ± 0.0
Val	5.36ValAla: 5.36 ± 0.077	1.007ValCys: 1.007 ± 0.036	4.032ValAsp: 4.032 ± 0.062	4.045ValGlu: 4.045 ± 0.071	3.01ValPhe: 3.01 ± 0.06	4.789ValGly: 4.789 ± 0.084	1.188ValHis: 1.188 ± 0.036	3.513ValIle: 3.513 ± 0.054	4.26ValLys: 4.26 ± 0.071	5.925ValLeu: 5.925 ± 0.091	1.749ValMet: 1.749 ± 0.04	3.343ValAsn: 3.343 ± 0.06	2.762ValPro: 2.762 ± 0.055	2.286ValGln: 2.286 ± 0.045	3.464ValArg: 3.464 ± 0.064	4.559ValSer: 4.559 ± 0.07	3.632ValThr: 3.632 ± 0.06	5.366ValVal: 5.366 ± 0.09	0.785ValTrp: 0.785 ± 0.029	2.702ValTyr: 2.702 ± 0.048	0.0ValXaa: 0.0 ± 0.0
Trp	0.912TrpAla: 0.912 ± 0.032	0.173TrpCys: 0.173 ± 0.014	0.7TrpAsp: 0.7 ± 0.028	0.677TrpGlu: 0.677 ± 0.022	0.549TrpPhe: 0.549 ± 0.023	0.987TrpGly: 0.987 ± 0.034	0.325TrpHis: 0.325 ± 0.018	0.654TrpIle: 0.654 ± 0.029	0.85TrpLys: 0.85 ± 0.034	1.323TrpLeu: 1.323 ± 0.046	0.398TrpMet: 0.398 ± 0.022	0.775TrpAsn: 0.775 ± 0.03	0.288TrpPro: 0.288 ± 0.019	0.689TrpGln: 0.689 ± 0.029	0.73TrpArg: 0.73 ± 0.027	0.611TrpSer: 0.611 ± 0.021	0.669TrpThr: 0.669 ± 0.03	0.754TrpVal: 0.754 ± 0.027	0.188TrpTrp: 0.188 ± 0.014	0.488TrpTyr: 0.488 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	3.337TyrAla: 3.337 ± 0.056	0.551TyrCys: 0.551 ± 0.026	2.679TyrAsp: 2.679 ± 0.06	2.334TyrGlu: 2.334 ± 0.052	1.972TyrPhe: 1.972 ± 0.048	3.063TyrGly: 3.063 ± 0.062	0.949TyrHis: 0.949 ± 0.029	2.368TyrIle: 2.368 ± 0.05	2.545TyrLys: 2.545 ± 0.046	3.663TyrLeu: 3.663 ± 0.06	1.022TyrMet: 1.022 ± 0.034	2.558TyrAsn: 2.558 ± 0.051	1.648TyrPro: 1.648 ± 0.042	1.518TyrGln: 1.518 ± 0.042	2.33TyrArg: 2.33 ± 0.051	2.51TyrSer: 2.51 ± 0.058	2.564TyrThr: 2.564 ± 0.053	2.787TyrVal: 2.787 ± 0.054	0.516TyrTrp: 0.516 ± 0.024	2.073TyrTyr: 2.073 ± 0.065	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2926 proteins (1017484 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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