Amino acid dipepetide frequency for Leptidea sinapis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.305AlaAla: 6.305 ± 0.058	1.491AlaCys: 1.491 ± 0.07	3.232AlaAsp: 3.232 ± 0.022	3.965AlaGlu: 3.965 ± 0.029	2.197AlaPhe: 2.197 ± 0.019	3.937AlaGly: 3.937 ± 0.035	1.613AlaHis: 1.613 ± 0.017	3.432AlaIle: 3.432 ± 0.025	3.54AlaLys: 3.54 ± 0.034	6.272AlaLeu: 6.272 ± 0.055	1.464AlaMet: 1.464 ± 0.021	2.603AlaAsn: 2.603 ± 0.02	3.612AlaPro: 3.612 ± 0.036	2.356AlaGln: 2.356 ± 0.021	3.833AlaArg: 3.833 ± 0.026	4.743AlaSer: 4.743 ± 0.038	3.682AlaThr: 3.682 ± 0.032	4.467AlaVal: 4.467 ± 0.025	0.693AlaTrp: 0.693 ± 0.012	1.757AlaTyr: 1.757 ± 0.018	0.001AlaXaa: 0.001 ± 0.0
Cys	1.365CysAla: 1.365 ± 0.027	0.544CysCys: 0.544 ± 0.011	1.253CysAsp: 1.253 ± 0.021	1.346CysGlu: 1.346 ± 0.036	0.771CysPhe: 0.771 ± 0.013	1.703CysGly: 1.703 ± 0.085	0.529CysHis: 0.529 ± 0.012	1.282CysIle: 1.282 ± 0.064	1.265CysLys: 1.265 ± 0.04	1.971CysLeu: 1.971 ± 0.051	0.449CysMet: 0.449 ± 0.011	1.057CysAsn: 1.057 ± 0.028	1.223CysPro: 1.223 ± 0.067	0.819CysGln: 0.819 ± 0.035	1.44CysArg: 1.44 ± 0.089	1.9CysSer: 1.9 ± 0.078	1.266CysThr: 1.266 ± 0.056	1.601CysVal: 1.601 ± 0.065	0.242CysTrp: 0.242 ± 0.006	0.668CysTyr: 0.668 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	3.297AspAla: 3.297 ± 0.023	1.15AspCys: 1.15 ± 0.039	3.79AspAsp: 3.79 ± 0.031	4.223AspGlu: 4.223 ± 0.033	2.115AspPhe: 2.115 ± 0.02	3.105AspGly: 3.105 ± 0.026	1.159AspHis: 1.159 ± 0.013	3.723AspIle: 3.723 ± 0.028	3.517AspLys: 3.517 ± 0.03	4.854AspLeu: 4.854 ± 0.04	1.272AspMet: 1.272 ± 0.014	2.825AspAsn: 2.825 ± 0.021	2.577AspPro: 2.577 ± 0.062	1.601AspGln: 1.601 ± 0.018	2.619AspArg: 2.619 ± 0.027	4.222AspSer: 4.222 ± 0.035	3.016AspThr: 3.016 ± 0.025	3.738AspVal: 3.738 ± 0.025	0.632AspTrp: 0.632 ± 0.011	1.821AspTyr: 1.821 ± 0.02	0.0AspXaa: 0.0 ± 0.0
Glu	4.042GluAla: 4.042 ± 0.031	1.59GluCys: 1.59 ± 0.099	3.887GluAsp: 3.887 ± 0.034	5.514GluGlu: 5.514 ± 0.057	2.094GluPhe: 2.094 ± 0.02	3.05GluGly: 3.05 ± 0.031	1.478GluHis: 1.478 ± 0.016	3.952GluIle: 3.952 ± 0.03	5.056GluLys: 5.056 ± 0.059	5.832GluLeu: 5.832 ± 0.053	1.588GluMet: 1.588 ± 0.016	3.728GluAsn: 3.728 ± 0.029	2.759GluPro: 2.759 ± 0.029	2.61GluGln: 2.61 ± 0.028	3.872GluArg: 3.872 ± 0.035	4.5GluSer: 4.5 ± 0.036	3.617GluThr: 3.617 ± 0.029	3.851GluVal: 3.851 ± 0.028	0.709GluTrp: 0.709 ± 0.012	2.054GluTyr: 2.054 ± 0.018	0.0GluXaa: 0.0 ± 0.0
Phe	2.129PheAla: 2.129 ± 0.019	0.821PheCys: 0.821 ± 0.014	2.121PheAsp: 2.121 ± 0.018	2.117PheGlu: 2.117 ± 0.019	1.421PhePhe: 1.421 ± 0.02	2.329PheGly: 2.329 ± 0.029	0.892PheHis: 0.892 ± 0.013	2.268PheIle: 2.268 ± 0.021	2.208PheLys: 2.208 ± 0.021	3.343PheLeu: 3.343 ± 0.035	0.862PheMet: 0.862 ± 0.013	1.886PheAsn: 1.886 ± 0.02	1.534PhePro: 1.534 ± 0.018	1.264PheGln: 1.264 ± 0.012	1.816PheArg: 1.816 ± 0.019	2.738PheSer: 2.738 ± 0.025	2.173PheThr: 2.173 ± 0.02	2.416PheVal: 2.416 ± 0.022	0.426PheTrp: 0.426 ± 0.009	1.349PheTyr: 1.349 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	3.918GlyAla: 3.918 ± 0.037	1.111GlyCys: 1.111 ± 0.029	3.123GlyAsp: 3.123 ± 0.037	3.156GlyGlu: 3.156 ± 0.03	2.174GlyPhe: 2.174 ± 0.021	4.163GlyGly: 4.163 ± 0.055	1.406GlyHis: 1.406 ± 0.017	2.903GlyIle: 2.903 ± 0.026	3.174GlyLys: 3.174 ± 0.029	4.537GlyLeu: 4.537 ± 0.034	1.168GlyMet: 1.168 ± 0.018	2.482GlyAsn: 2.482 ± 0.03	2.486GlyPro: 2.486 ± 0.044	1.913GlyGln: 1.913 ± 0.022	3.158GlyArg: 3.158 ± 0.028	4.384GlySer: 4.384 ± 0.044	2.988GlyThr: 2.988 ± 0.026	3.697GlyVal: 3.697 ± 0.027	0.692GlyTrp: 0.692 ± 0.011	2.036GlyTyr: 2.036 ± 0.03	0.0GlyXaa: 0.0 ± 0.0
His	1.471HisAla: 1.471 ± 0.016	0.579HisCys: 0.579 ± 0.012	1.183HisAsp: 1.183 ± 0.015	1.356HisGlu: 1.356 ± 0.015	0.947HisPhe: 0.947 ± 0.013	1.356HisGly: 1.356 ± 0.016	0.868HisHis: 0.868 ± 0.018	1.456HisIle: 1.456 ± 0.016	1.449HisLys: 1.449 ± 0.016	2.368HisLeu: 2.368 ± 0.024	0.617HisMet: 0.617 ± 0.012	1.227HisAsn: 1.227 ± 0.016	1.314HisPro: 1.314 ± 0.014	0.99HisGln: 0.99 ± 0.014	1.432HisArg: 1.432 ± 0.016	1.938HisSer: 1.938 ± 0.018	1.41HisThr: 1.41 ± 0.016	1.521HisVal: 1.521 ± 0.014	0.304HisTrp: 0.304 ± 0.007	0.894HisTyr: 0.894 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	3.47IleAla: 3.47 ± 0.025	1.425IleCys: 1.425 ± 0.049	3.232IleAsp: 3.232 ± 0.027	3.773IleGlu: 3.773 ± 0.033	2.218IlePhe: 2.218 ± 0.028	2.811IleGly: 2.811 ± 0.03	1.313IleHis: 1.313 ± 0.015	3.606IleIle: 3.606 ± 0.028	3.895IleLys: 3.895 ± 0.033	5.156IleLeu: 5.156 ± 0.041	1.24IleMet: 1.24 ± 0.014	3.241IleAsn: 3.241 ± 0.044	2.84IlePro: 2.84 ± 0.02	2.216IleGln: 2.216 ± 0.021	2.726IleArg: 2.726 ± 0.022	4.545IleSer: 4.545 ± 0.031	3.378IleThr: 3.378 ± 0.029	3.654IleVal: 3.654 ± 0.024	0.573IleTrp: 0.573 ± 0.011	1.8IleTyr: 1.8 ± 0.019	0.0IleXaa: 0.0 ± 0.0
Lys	3.477LysAla: 3.477 ± 0.032	1.467LysCys: 1.467 ± 0.056	3.514LysAsp: 3.514 ± 0.031	4.775LysGlu: 4.775 ± 0.047	2.158LysPhe: 2.158 ± 0.022	2.628LysGly: 2.628 ± 0.024	1.58LysHis: 1.58 ± 0.017	3.984LysIle: 3.984 ± 0.036	5.409LysLys: 5.409 ± 0.051	5.872LysLeu: 5.872 ± 0.051	1.557LysMet: 1.557 ± 0.016	3.427LysAsn: 3.427 ± 0.028	3.217LysPro: 3.217 ± 0.041	2.653LysGln: 2.653 ± 0.03	3.697LysArg: 3.697 ± 0.03	4.803LysSer: 4.803 ± 0.046	3.617LysThr: 3.617 ± 0.033	3.704LysVal: 3.704 ± 0.03	0.664LysTrp: 0.664 ± 0.014	2.382LysTyr: 2.382 ± 0.024	0.001LysXaa: 0.001 ± 0.0
Leu	6.196LeuAla: 6.196 ± 0.041	1.949LeuCys: 1.949 ± 0.025	4.835LeuAsp: 4.835 ± 0.038	5.932LeuGlu: 5.932 ± 0.053	3.246LeuPhe: 3.246 ± 0.032	4.42LeuGly: 4.42 ± 0.037	2.295LeuHis: 2.295 ± 0.024	4.487LeuIle: 4.487 ± 0.041	6.135LeuLys: 6.135 ± 0.055	8.685LeuLeu: 8.685 ± 0.078	1.984LeuMet: 1.984 ± 0.022	4.469LeuAsn: 4.469 ± 0.032	4.745LeuPro: 4.745 ± 0.03	4.218LeuGln: 4.218 ± 0.035	5.395LeuArg: 5.395 ± 0.045	7.081LeuSer: 7.081 ± 0.037	4.901LeuThr: 4.901 ± 0.035	5.431LeuVal: 5.431 ± 0.044	0.96LeuTrp: 0.96 ± 0.015	2.766LeuTyr: 2.766 ± 0.029	0.001LeuXaa: 0.001 ± 0.0
Met	1.609MetAla: 1.609 ± 0.016	0.485MetCys: 0.485 ± 0.012	1.243MetAsp: 1.243 ± 0.014	1.549MetGlu: 1.549 ± 0.017	0.949MetPhe: 0.949 ± 0.014	1.164MetGly: 1.164 ± 0.019	0.495MetHis: 0.495 ± 0.01	1.133MetIle: 1.133 ± 0.014	1.571MetLys: 1.571 ± 0.017	2.022MetLeu: 2.022 ± 0.022	0.654MetMet: 0.654 ± 0.011	1.122MetAsn: 1.122 ± 0.015	1.084MetPro: 1.084 ± 0.013	0.905MetGln: 0.905 ± 0.013	1.217MetArg: 1.217 ± 0.015	1.907MetSer: 1.907 ± 0.017	1.268MetThr: 1.268 ± 0.014	1.247MetVal: 1.247 ± 0.014	0.279MetTrp: 0.279 ± 0.007	0.734MetTyr: 0.734 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	2.793AsnAla: 2.793 ± 0.046	1.012AsnCys: 1.012 ± 0.025	2.761AsnAsp: 2.761 ± 0.021	3.33AsnGlu: 3.33 ± 0.025	1.887AsnPhe: 1.887 ± 0.019	2.803AsnGly: 2.803 ± 0.028	1.16AsnHis: 1.16 ± 0.028	3.775AsnIle: 3.775 ± 0.029	3.597AsnLys: 3.597 ± 0.032	4.364AsnLeu: 4.364 ± 0.034	1.246AsnMet: 1.246 ± 0.017	3.259AsnAsn: 3.259 ± 0.032	2.373AsnPro: 2.373 ± 0.068	1.827AsnGln: 1.827 ± 0.022	2.251AsnArg: 2.251 ± 0.02	3.934AsnSer: 3.934 ± 0.034	2.95AsnThr: 2.95 ± 0.023	3.299AsnVal: 3.299 ± 0.021	0.499AsnTrp: 0.499 ± 0.009	1.799AsnTyr: 1.799 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	3.657ProAla: 3.657 ± 0.034	1.183ProCys: 1.183 ± 0.117	2.745ProAsp: 2.745 ± 0.021	3.529ProGlu: 3.529 ± 0.051	1.719ProPhe: 1.719 ± 0.022	2.901ProGly: 2.901 ± 0.048	1.336ProHis: 1.336 ± 0.017	2.634ProIle: 2.634 ± 0.024	2.944ProLys: 2.944 ± 0.03	4.229ProLeu: 4.229 ± 0.034	0.999ProMet: 0.999 ± 0.015	2.444ProAsn: 2.444 ± 0.051	4.391ProPro: 4.391 ± 0.058	2.154ProGln: 2.154 ± 0.026	2.817ProArg: 2.817 ± 0.028	4.233ProSer: 4.233 ± 0.045	3.054ProThr: 3.054 ± 0.026	3.402ProVal: 3.402 ± 0.028	0.502ProTrp: 0.502 ± 0.01	1.628ProTyr: 1.628 ± 0.024	0.001ProXaa: 0.001 ± 0.0
Gln	2.38GlnAla: 2.38 ± 0.022	0.925GlnCys: 0.925 ± 0.037	1.809GlnAsp: 1.809 ± 0.017	2.554GlnGlu: 2.554 ± 0.023	1.328GlnPhe: 1.328 ± 0.015	1.755GlnGly: 1.755 ± 0.022	1.118GlnHis: 1.118 ± 0.017	2.181GlnIle: 2.181 ± 0.021	2.518GlnLys: 2.518 ± 0.025	3.74GlnLeu: 3.74 ± 0.038	0.993GlnMet: 0.993 ± 0.015	2.242GlnAsn: 2.242 ± 0.024	2.057GlnPro: 2.057 ± 0.026	2.172GlnGln: 2.172 ± 0.048	2.346GlnArg: 2.346 ± 0.024	2.76GlnSer: 2.76 ± 0.026	2.132GlnThr: 2.132 ± 0.02	2.197GlnVal: 2.197 ± 0.019	0.462GlnTrp: 0.462 ± 0.01	1.397GlnTyr: 1.397 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	3.875ArgAla: 3.875 ± 0.032	1.249ArgCys: 1.249 ± 0.027	3.053ArgAsp: 3.053 ± 0.025	3.477ArgGlu: 3.477 ± 0.029	1.843ArgPhe: 1.843 ± 0.018	3.095ArgGly: 3.095 ± 0.03	1.558ArgHis: 1.558 ± 0.017	2.806ArgIle: 2.806 ± 0.025	3.645ArgLys: 3.645 ± 0.029	5.025ArgLeu: 5.025 ± 0.038	1.183ArgMet: 1.183 ± 0.014	2.746ArgAsn: 2.746 ± 0.022	2.952ArgPro: 2.952 ± 0.034	2.219ArgGln: 2.219 ± 0.021	4.551ArgArg: 4.551 ± 0.042	4.329ArgSer: 4.329 ± 0.044	2.876ArgThr: 2.876 ± 0.022	3.326ArgVal: 3.326 ± 0.024	0.68ArgTrp: 0.68 ± 0.011	1.726ArgTyr: 1.726 ± 0.019	0.0ArgXaa: 0.0 ± 0.0
Ser	4.764SerAla: 4.764 ± 0.034	1.797SerCys: 1.797 ± 0.085	4.602SerAsp: 4.602 ± 0.031	4.922SerGlu: 4.922 ± 0.031	2.724SerPhe: 2.724 ± 0.026	4.619SerGly: 4.619 ± 0.038	1.857SerHis: 1.857 ± 0.019	4.134SerIle: 4.134 ± 0.03	4.656SerLys: 4.656 ± 0.037	6.856SerLeu: 6.856 ± 0.045	1.623SerMet: 1.623 ± 0.016	3.966SerAsn: 3.966 ± 0.031	4.672SerPro: 4.672 ± 0.066	2.93SerGln: 2.93 ± 0.025	4.23SerArg: 4.23 ± 0.04	7.483SerSer: 7.483 ± 0.065	4.695SerThr: 4.695 ± 0.037	4.78SerVal: 4.78 ± 0.032	0.84SerTrp: 0.84 ± 0.013	2.313SerTyr: 2.313 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	3.75ThrAla: 3.75 ± 0.032	1.305ThrCys: 1.305 ± 0.041	3.0ThrAsp: 3.0 ± 0.02	3.643ThrGlu: 3.643 ± 0.028	2.094ThrPhe: 2.094 ± 0.022	3.132ThrGly: 3.132 ± 0.03	1.353ThrHis: 1.353 ± 0.015	3.239ThrIle: 3.239 ± 0.025	3.396ThrLys: 3.396 ± 0.03	5.088ThrLeu: 5.088 ± 0.035	1.259ThrMet: 1.259 ± 0.015	2.802ThrAsn: 2.802 ± 0.024	3.507ThrPro: 3.507 ± 0.033	2.09ThrGln: 2.09 ± 0.02	2.808ThrArg: 2.808 ± 0.021	4.843ThrSer: 4.843 ± 0.038	3.801ThrThr: 3.801 ± 0.046	3.755ThrVal: 3.755 ± 0.028	0.63ThrTrp: 0.63 ± 0.011	1.712ThrTyr: 1.712 ± 0.019	0.001ThrXaa: 0.001 ± 0.0
Val	4.326ValAla: 4.326 ± 0.026	1.576ValCys: 1.576 ± 0.047	3.437ValAsp: 3.437 ± 0.025	4.014ValGlu: 4.014 ± 0.032	2.377ValPhe: 2.377 ± 0.024	3.222ValGly: 3.222 ± 0.026	1.537ValHis: 1.537 ± 0.017	3.581ValIle: 3.581 ± 0.024	3.872ValLys: 3.872 ± 0.038	5.826ValLeu: 5.826 ± 0.04	1.4ValMet: 1.4 ± 0.014	3.028ValAsn: 3.028 ± 0.036	3.268ValPro: 3.268 ± 0.027	2.445ValGln: 2.445 ± 0.018	3.377ValArg: 3.377 ± 0.026	4.803ValSer: 4.803 ± 0.025	3.922ValThr: 3.922 ± 0.029	4.343ValVal: 4.343 ± 0.029	0.715ValTrp: 0.715 ± 0.011	1.986ValTyr: 1.986 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	0.621TrpAla: 0.621 ± 0.012	0.255TrpCys: 0.255 ± 0.006	0.602TrpAsp: 0.602 ± 0.011	0.612TrpGlu: 0.612 ± 0.009	0.441TrpPhe: 0.441 ± 0.01	0.591TrpGly: 0.591 ± 0.014	0.267TrpHis: 0.267 ± 0.006	0.635TrpIle: 0.635 ± 0.011	0.692TrpLys: 0.692 ± 0.011	1.141TrpLeu: 1.141 ± 0.015	0.313TrpMet: 0.313 ± 0.007	0.532TrpAsn: 0.532 ± 0.01	0.451TrpPro: 0.451 ± 0.01	0.436TrpGln: 0.436 ± 0.009	0.828TrpArg: 0.828 ± 0.012	0.87TrpSer: 0.87 ± 0.013	0.608TrpThr: 0.608 ± 0.011	0.631TrpVal: 0.631 ± 0.01	0.213TrpTrp: 0.213 ± 0.007	0.371TrpTyr: 0.371 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.749TyrAla: 1.749 ± 0.019	0.78TyrCys: 0.78 ± 0.015	1.833TyrAsp: 1.833 ± 0.02	2.0TyrGlu: 2.0 ± 0.02	1.413TyrPhe: 1.413 ± 0.017	1.885TyrGly: 1.885 ± 0.023	0.865TyrHis: 0.865 ± 0.012	1.902TyrIle: 1.902 ± 0.021	2.047TyrLys: 2.047 ± 0.02	2.95TyrLeu: 2.95 ± 0.028	0.764TyrMet: 0.764 ± 0.011	1.832TyrAsn: 1.832 ± 0.02	1.438TyrPro: 1.438 ± 0.018	1.247TyrGln: 1.247 ± 0.014	1.8TyrArg: 1.8 ± 0.02	2.45TyrSer: 2.45 ± 0.022	1.853TyrThr: 1.853 ± 0.018	1.992TyrVal: 1.992 ± 0.016	0.391TyrTrp: 0.391 ± 0.009	1.327TyrTyr: 1.327 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.001XaaAla: 0.001 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.001XaaLys: 0.001 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.001XaaMet: 0.001 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.001XaaArg: 0.001 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.001XaaTyr: 0.001 ± 0.0	0.075XaaXaa: 0.075 ± 0.021

Statistics based on 19862 proteins (7582099 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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